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Volumn 16, Issue , 2016, Pages

Overview of medicinally important diterpenoids derived from plastids

Author keywords

Diterpenoid; Ginkgolide; Oridonin; Paclitaxel; Plastid; Tanshinone; Triptolide

Indexed keywords

BACCATIN III; DITERPENOID; GINKGOLIDE; ORIDONIN; PACLITAXEL; SESQUITERPENE DERIVATIVE; TANSHINONE; TRIPTOLIDE; ABIETANE DERIVATIVE; DITERPENE; EPOXIDE; KAURANE DERIVATIVE; PHENANTHRENE DERIVATIVE;

EID: 85007310567     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/1389557516666160614005244     Document Type: Review
Times cited : (20)

References (188)
  • 1
    • 34250785114 scopus 로고    scopus 로고
    • The function of terpene natural products in the natural world
    • Gershenzon, J.; Dudareva, N. The function of terpene natural products in the natural world. Nat. Chem. Biol., 2007, 3, 408-414.
    • (2007) Nat. Chem. Biol , vol.3 , pp. 408-414
    • Gershenzon, J.1    Dudareva, N.2
  • 4
    • 84938901085 scopus 로고    scopus 로고
    • Secondary metabolites in fungus-plant interactions
    • Pusztahelyi, T.; Holb, I.J.; Pócsi, I. Secondary metabolites in fungus-plant interactions. Front. Plant Sci., 2015, 6, 573.
    • (2015) Front. Plant Sci. , vol.6 , pp. 573
    • Pusztahelyi, T.1    Holb, I.J.2    Pócsi, I.3
  • 5
    • 67651146398 scopus 로고    scopus 로고
    • Nature: A vital source of leads for anticancer drug development
    • Cragg, G.M.; Newman, D.J. Nature: a vital source of leads for anticancer drug development. Phytochem. Rev., 2009, 8, 313-331.
    • (2009) Phytochem. Rev. , vol.8 , pp. 313-331
    • Cragg, G.M.1    Newman, D.J.2
  • 6
    • 34147178365 scopus 로고    scopus 로고
    • Chimeras of two isoprenoid synthases catalyze all four coupling reactions in isoprenoid biosynthesis
    • Thulasiram, H.V.; Erickson, H.K.; Poulter, C.D. Chimeras of two isoprenoid synthases catalyze all four coupling reactions in isoprenoid biosynthesis. Science, 2007, 316, 73-76.
    • (2007) Science , vol.316 , pp. 73-76
    • Thulasiram, H.V.1    Erickson, H.K.2    Poulter, C.D.3
  • 7
    • 84933676921 scopus 로고    scopus 로고
    • Effects of monoterpenes on ion channels of excitable cells
    • Oz, M.; Lozon, Y.; Sultan, A.; Yang, K.H.; Galadari, S. Effects of monoterpenes on ion channels of excitable cells. Pharmacol. Ther., 2015, 152, 83-97.
    • (2015) Pharmacol. Ther. , vol.152 , pp. 83-97
    • Oz, M.1    Lozon, Y.2    Sultan, A.3    Yang, K.H.4    Galadari, S.5
  • 8
    • 85015334139 scopus 로고    scopus 로고
    • Plant terpenes: Defense responses, phylogenetic analysis, regulation and clinical applications
    • Singh, B.; Sharma, R.A. Plant terpenes: defense responses, phylogenetic analysis, regulation and clinical applications. 3 Biotech., 2015, 5(2), 129-151.
    • (2015) 3 Biotech. , vol.5 , Issue.2 , pp. 129-151
    • Singh, B.1    Sharma, R.A.2
  • 9
    • 0030077655 scopus 로고    scopus 로고
    • Carotenoids 2: Genetics and molecular biology of carotenoid pigment biosynthesis
    • Armstrong, G.A.; Hearst, J.E. Carotenoids 2: Genetics and molecular biology of carotenoid pigment biosynthesis. FASEB J., 1996, 10, 228-237.
    • (1996) FASEB J. , vol.10 , pp. 228-237
    • Armstrong, G.A.1    Hearst, J.E.2
  • 10
    • 0002708926 scopus 로고
    • Terpenoid metabolism in plastids: Localization of alpha-tocopherol synthesis in Capsicum chromoplasts
    • Camara, B.; Bardat, F.; Seye, A.; D’Harlingue, A.; Monéger, R. Terpenoid metabolism in plastids: localization of alpha-tocopherol synthesis in Capsicum chromoplasts. Plant Physiol., 1982, 70, 1562-1563.
    • (1982) Plant Physiol. , vol.70 , pp. 1562-1563
    • Camara, B.1    Bardat, F.2    Seye, A.3    D’Harlingue, A.4    Monéger, R.5
  • 12
    • 84883054025 scopus 로고    scopus 로고
    • Bioengineering of plant (Tri)terpenoids: From metabolic engineering of plants to synthetic biology in vivo and in vitro
    • Moses, T.; Pollier J.; Thevelein, J.M.; Goossens, A. Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro. New Phytol., 2013, 200, 27-43.
    • (2013) New Phytol. , vol.200 , pp. 27-43
    • Moses, T.1    Pollier, J.2    Thevelein, J.M.3    Goossens, A.4
  • 13
    • 84861060144 scopus 로고    scopus 로고
    • Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza
    • Ma, Y.; Yuan, L.; Wu, B.; Li, X.; Chen, S.; Lu, S. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. J. Exp. Bot., 2012, 63, 2809-2823.
    • (2012) J. Exp. Bot. , vol.63 , pp. 2809-2823
    • Ma, Y.1    Yuan, L.2    Wu, B.3    Li, X.4    Chen, S.5    Lu, S.6
  • 15
    • 67650915528 scopus 로고    scopus 로고
    • Unravelling the regulatory mechanisms that modulate the MEP pathway in higher plants
    • Cordoba, E.; Salmi, M.; León, P. Unravelling the regulatory mechanisms that modulate the MEP pathway in higher plants. J. Exp. Bot., 2009, 60, 2933-2943.
    • (2009) J. Exp. Bot. , vol.60 , pp. 2933-2943
    • Cordoba, E.1    Salmi, M.2    León, P.3
  • 16
    • 33646157726 scopus 로고    scopus 로고
    • Terpene synthases and the regulation, diversity and biological roles of terpene metabolism
    • Tholl, D. Terpene synthases and the regulation, diversity and biological roles of terpene metabolism. Curr. Opin. Plant Biol., 2006, 9, 297-304.
    • (2006) Curr. Opin. Plant Biol. , vol.9 , pp. 297-304
    • Tholl, D.1
  • 17
    • 77950001453 scopus 로고    scopus 로고
    • Distribution of tanshinones in the genus Salvia (Family Lamiaceae) from China and its systematic significance
    • Li, M.H.; Peng, Y.; Xiao, P.G. Distribution of tanshinones in the genus Salvia (family Lamiaceae) from China and its systematic significance. J. Syst. Evol., 2010, 48, 118-122.
    • (2010) J. Syst. Evol. , vol.48 , pp. 118-122
    • Li, M.H.1    Peng, Y.2    Xiao, P.G.3
  • 18
    • 0033764459 scopus 로고    scopus 로고
    • An introduction to the biosynthesis of chemicals used in plant-microbe communication
    • Paiva, N.L. An introduction to the biosynthesis of chemicals used in plant-microbe communication. J. Plant Growth Regul., 2000, 19, 131-143.
    • (2000) J. Plant Growth Regul. , vol.19 , pp. 131-143
    • Paiva, N.L.1
  • 19
    • 0028814372 scopus 로고
    • Monoterpene and sesquiterpene biosynthesis in glandular trichomes of peppermint (Mentha x piperita) rely exclusively on plastid-derived isopentenyl diphosphate
    • McCaskill, D.; Croteau, R. Monoterpene and sesquiterpene biosynthesis in glandular trichomes of peppermint (Mentha x piperita) rely exclusively on plastid-derived isopentenyl diphosphate. Planta, 1995, 197, 49-56.
    • (1995) Planta , vol.197 , pp. 49-56
    • McCaskill, D.1    Croteau, R.2
  • 20
    • 84871677371 scopus 로고    scopus 로고
    • Terpenoid biosynthesis in trichomes-current status and future opportunities
    • Lange, B.M.; Turner, G.W. Terpenoid biosynthesis in trichomes-current status and future opportunities. Plant Biotechnol. J., 2013, 11, 2-22.
    • (2013) Plant Biotechnol. J. , vol.11 , pp. 2-22
    • Lange, B.M.1    Turner, G.W.2
  • 21
    • 79960807863 scopus 로고    scopus 로고
    • The biosynthesis of isoprenoids and the mechanisms regulating it in plants
    • Okada, K. The biosynthesis of isoprenoids and the mechanisms regulating it in plants. Biosci. Biotechnol. Biochem., 2011, 75, 1219-1225.
    • (2011) Biosci. Biotechnol. Biochem. , vol.75 , pp. 1219-1225
    • Okada, K.1
  • 22
    • 84997512905 scopus 로고    scopus 로고
    • Biosynthesis and regulation of secondary terpenoid metabolism in plants
    • Wang, L.J.; Fang, X.; Yang, C.Q.; Li, J.; Chen, X.Y. Biosynthesis and regulation of secondary terpenoid metabolism in plants. Sci. Sin. Vitae, 2013, 43, 1030-1046.
    • (2013) Sci. Sin. Vitae , vol.43 , pp. 1030-1046
    • Wang, L.J.1    Fang, X.2    Yang, C.Q.3    Li, J.4    Chen, X.Y.5
  • 23
    • 0038723724 scopus 로고    scopus 로고
    • Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: Unidirectional transport of intermediates across the chloroplast envelope membrane
    • Bick, J.A.; Lange, B.M. Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: unidirectional transport of intermediates across the chloroplast envelope membrane. Arch. Biochem. Biophys., 2003, 415, 146-154.
    • (2003) Arch. Biochem. Biophys. , vol.415 , pp. 146-154
    • Bick, J.A.1    Lange, B.M.2
  • 24
    • 0034002980 scopus 로고    scopus 로고
    • Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis
    • Okada, K.; Saito, T.; Nakagawa, T.; Kamiya Y. Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis. Plant Physiol., 2000, 122, 1045-1056.
    • (2000) Plant Physiol , vol.122 , pp. 1045-1056
    • Okada, K.1    Saito, T.2    Nakagawa, T.3    Kamiya, Y.4
  • 25
    • 0030919438 scopus 로고    scopus 로고
    • The Arabidopsis thaliana FPS1 gene generates a novel mRNA that encodes a mitochondrial farnesyl-diphosphate synthase isoform
    • Cunillera, N.; Boronat, A.; Ferrer, A. The Arabidopsis thaliana FPS1 gene generates a novel mRNA that encodes a mitochondrial farnesyl-diphosphate synthase isoform. J. Biol. Chem., 1997, 272, 15381-15388.
    • (1997) J. Biol. Chem. , vol.272 , pp. 15381-15388
    • Cunillera, N.1    Boronat, A.2    Ferrer, A.3
  • 26
    • 0028216631 scopus 로고
    • Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins
    • Grunler, J.; Ericsson, J.; Dallner, G. Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins. Biochim. Biophys. Acta, 1994, 1212, 259-277.
    • (1994) Biochim. Biophys. Acta , vol.1212 , pp. 259-277
    • Grunler, J.1    Ericsson, J.2    Dallner, G.3
  • 27
    • 0033103646 scopus 로고    scopus 로고
    • Localization of farnesyl diphosphate synthase in chloroplasts
    • Sanmiya, K.; Ueno, O.; Matsuoka, M.; Yamamoto, N. Localization of farnesyl diphosphate synthase in chloroplasts. Plant Cell Physiol., 1999, 40, 348-354.
    • (1999) Plant Cell Physiol. , vol.40 , pp. 348-354
    • Sanmiya, K.1    Ueno, O.2    Matsuoka, M.3    Yamamoto, N.4
  • 28
    • 33747215629 scopus 로고    scopus 로고
    • Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves
    • Bartram, S.; Jux, A.; Gleixner, G.; Boland, W. Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves. Phytochemistry, 2006, 67, 1661-1672.
    • (2006) Phytochemistry , vol.67 , pp. 1661-1672
    • Bartram, S.1    Jux, A.2    Gleixner, G.3    Boland, W.4
  • 30
    • 0015211527 scopus 로고
    • Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
    • Wani, M.C.; Taylor, H.L.; Wall, M.E.; Coggon, P.; McPhail, A.T. Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Chem. Soc., 1971, 93, 2325-2333.
    • (1971) J. Am. Chem. Soc. , vol.93 , pp. 2325-2333
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3    Coggon, P.4    McPhail, A.T.5
  • 31
    • 84872288933 scopus 로고    scopus 로고
    • Update on taxane development: New analogs and new formulations
    • Yared, J.A.; Tkaczuk, K.H. Update on taxane development: new analogs and new formulations. Drug Des. Devel. Ther., 2012, 6, 371-384.
    • (2012) Drug Des. Devel. Ther , vol.6 , pp. 371-384
    • Yared, J.A.1    Tkaczuk, K.H.2
  • 33
    • 84925541901 scopus 로고    scopus 로고
    • Stabilization of microtubules by taxane diterpenoids: Insight from docking and MD simulations
    • Yadava, U.; Gupta, H.; Roychoudhury, M. Stabilization of microtubules by taxane diterpenoids: insight from docking and MD simulations. J. Biol. Phys., 2015, 41(2), 117-133.
    • (2015) J. Biol. Phys. , vol.41 , Issue.2 , pp. 117-133
    • Yadava, U.1    Gupta, H.2    Roychoudhury, M.3
  • 34
    • 0000052734 scopus 로고
    • Taxol and taxotere: Discovery, chemistry and structure-activity relationships
    • Guenard, D.; Gueritte-Voegelein, F.; Potier, P. Taxol and taxotere: discovery, chemistry and structure-activity relationships. Accounts Chem. Res., 1993, 26, 160-167.
    • (1993) Accounts Chem. Res. , vol.26 , pp. 160-167
    • Guenard, D.1    Gueritte-Voegelein, F.2    Potier, P.3
  • 37
    • 0035838940 scopus 로고    scopus 로고
    • Taxol biosynthetic genes
    • Walker, K.; Croteau, R. Taxol biosynthetic genes. Phytochemistry, 2001, 58, 1-7.
    • (2001) Phytochemistry , vol.58 , pp. 1-7
    • Walker, K.1    Croteau, R.2
  • 38
    • 84861303184 scopus 로고    scopus 로고
    • The early stages of taxol biosynthesis: An interim report on the synthesis and identification of early pathway metabolites
    • Guerra-Bubb, J.; Croteau, R.; Williams, R.M. The early stages of taxol biosynthesis: an interim report on the synthesis and identification of early pathway metabolites. Nat. Prod. Rep., 2012, 29, 683-669.
    • (2012) Nat. Prod. Rep. , vol.29 , pp. 669-683
    • Guerra-Bubb, J.1    Croteau, R.2    Williams, R.M.3
  • 39
    • 0030003383 scopus 로고    scopus 로고
    • Studies on the biosynthesis of taxol: The taxane carbon skeleton is not of mevalonoid origin
    • Eisenreich, W.; Menhard, B.; Hylands, P.J.; Zenk, M.H.; Bacher, A. Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin. Proc. Natl. Acad. Sci. USA, 1996, 93, 6431-6436.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6431-6436
    • Eisenreich, W.1    Menhard, B.2    Hylands, P.J.3    Zenk, M.H.4    Bacher, A.5
  • 40
    • 0343614184 scopus 로고    scopus 로고
    • A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway
    • Lange, B.M.; Wildung, M.R.; McCaskill, D.; Croteau, R. A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. Proc. Natl. Acad. Sci. USA, 1998, 95, 2100-2104.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2100-2104
    • Lange, B.M.1    Wildung, M.R.2    McCaskill, D.3    Croteau, R.4
  • 41
    • 0026801417 scopus 로고
    • Biosynthetic building blocks of Taxus canadensis taxanes
    • Zamir, L.O.; Nedea, M.E.; Gameau, F.X. Biosynthetic building blocks of Taxus canadensis taxanes. Tetrahedron Lett., 1992, 33, 5235-5236.
    • (1992) Tetrahedron Lett. , vol.33 , pp. 5235-5236
    • Zamir, L.O.1    Nedea, M.E.2    Gameau, F.X.3
  • 43
    • 78649854044 scopus 로고    scopus 로고
    • New insights into the shikimate and aromatic amino acids biosynthesis pathways in plants
    • Tzin, V.; Galili, G. New insights into the shikimate and aromatic amino acids biosynthesis pathways in plants. Mol. Plant., 2010, 3, 956-972.
    • (2010) Mol. Plant. , vol.3 , pp. 956-972
    • Tzin, V.1    Galili, G.2
  • 44
    • 84869808716 scopus 로고    scopus 로고
    • The shikimate pathway and aromatic amino acid biosynthesis in plants
    • Maeda, H.; Dudareva, N. The shikimate pathway and aromatic amino acid biosynthesis in plants. Annu. Rev. Plant Biol., 2012, 63, 73-105.
    • (2012) Annu. Rev. Plant Biol. , vol.63 , pp. 73-105
    • Maeda, H.1    Dudareva, N.2
  • 46
    • 0027518386 scopus 로고
    • Biosynthesis of taxoids-Mode of formation of the taxol side chain
    • Fleming, P.E.; Mocek, U.; Floss, H.G. Biosynthesis of taxoids-Mode of formation of the taxol side chain. J. Am. Chem. Soc., 1993, 115, 805-807.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 805-807
    • Fleming, P.E.1    Mocek, U.2    Floss, H.G.3
  • 49
    • 0034838359 scopus 로고    scopus 로고
    • Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol
    • Huang, Q.; Roessner, C.A.; Croteau, R.; Scott, A.I. Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol. Bioorg. Med. Chem., 2001, 9, 2237-2242.
    • (2001) Bioorg. Med. Chem , vol.9 , pp. 2237-2242
    • Huang, Q.1    Roessner, C.A.2    Croteau, R.3    Scott, A.I.4
  • 50
    • 44749083814 scopus 로고    scopus 로고
    • Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards taxol (Paclitaxel) production
    • Engels, B.; Dahm, P.; Jennewein, S. Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards taxol (paclitaxel) production. Metab. Eng., 2008, 10, 201-206.
    • (2008) Metab. Eng , vol.10 , pp. 201-206
    • Engels, B.1    Dahm, P.2    Jennewein, S.3
  • 51
    • 33645573250 scopus 로고    scopus 로고
    • Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae. Biotechnol
    • Dejong, J.M.; Liu, Y.; Bollon, A.P.; Long, R.M.; Jennewein, S.; Williams, D.; Croteau, R.B. Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae. Biotechnol. Bioeng., 2006, 93, 212-224.
    • (2006) Bioeng. , vol.93 , pp. 212-224
    • Dejong, J.M.1    Liu, Y.2    Bollon, A.P.3    Long, R.M.4    Jennewein, S.5    Williams, D.6    Croteau, R.B.7
  • 52
    • 84926646130 scopus 로고    scopus 로고
    • Distributing a metabolic pathway among a microbial consortium enhances production of natural products
    • Zhou, K.; Qiao, K.; Edgar, S.; Stephanopoulos, G. Distributing a metabolic pathway among a microbial consortium enhances production of natural products. Nat. Biotechnol., 2015, 33(4), 377-383.
    • (2015) Nat. Biotechnol. , vol.33 , Issue.4 , pp. 377-383
    • Zhou, K.1    Qiao, K.2    Edgar, S.3    Stephanopoulos, G.4
  • 53
    • 6444235290 scopus 로고    scopus 로고
    • Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of taxol
    • Besumbes, O.; Sauret-Güeto, S.; Phillips, M.A.; Imperial, S.; Rodríguez-Concepción, M.; Boronat, A. Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of taxol. Biotechnol. Bioeng., 2004, 88, 168-175.
    • (2004) Biotechnol. Bioeng. , vol.88 , pp. 168-175
    • Besumbes, O.1    Sauret-Güeto, S.2    Phillips, M.A.3    Imperial, S.4    Rodríguez-Concepción, M.5    Boronat, A.6
  • 54
    • 69449084289 scopus 로고    scopus 로고
    • Production of taxa-4(5), 11(12)-diene by transgenic Physcomitrella patens
    • Anterola, A.; Shanle, E.; Perroud, P.F.; Quatrano, R. Production of taxa-4(5), 11(12)-diene by transgenic Physcomitrella patens. Transgenic Res., 2009, 18, 655-660.
    • (2009) Transgenic Res. , vol.18 , pp. 655-660
    • Anterola, A.1    Shanle, E.2    Perroud, P.F.3    Quatrano, R.4
  • 55
    • 84871446061 scopus 로고    scopus 로고
    • Production of taxadiene from cultured ginseng roots transformed with taxadiene synthase gene
    • Cha, M.; Shim, S.H.; Kim S.H.; Kim, O.T.; Lee, S.W.; Kwon, S.Y.; Baek, K.H. Production of taxadiene from cultured ginseng roots transformed with taxadiene synthase gene. BMB Rep., 2012, 45, 589-594.
    • (2012) BMB Rep. , vol.45 , pp. 589-594
    • Cha, M.1    Shim, S.H.2    Kim, S.H.3    Kim, O.T.4    Lee, S.W.5    Kwon, S.Y.6    Baek, K.H.7
  • 57
    • 0019783912 scopus 로고
    • Structural analysis and biochemical study of isolated products of the yew: Taxus baccata L. (Taxaceae)
    • Chauviere, G.; Guenard, D.; Picot, F.; Senilh, V.; Potier, P. Structural analysis and biochemical study of isolated products of the yew: Taxus baccata L. (Taxaceae). C. R. Seances Acad. Sci., Ser. 2, 1981, 293, 501-503.
    • (1981) C. R. Seances Acad. Sci., Ser. , vol.2 , Issue.293 , pp. 501-503
    • Chauviere, G.1    Guenard, D.2    Picot, F.3    Senilh, V.4    Potier, P.5
  • 58
    • 34249778118 scopus 로고    scopus 로고
    • Paclitaxel from primary taxanes: A perspective on creative invention in organozirconium chemistry
    • Ganem, B.; Franke, R.R. Paclitaxel from primary taxanes: a perspective on creative invention in organozirconium chemistry. J. Org. Chem., 2007, 72, 3981-3987.
    • (2007) J. Org. Chem. , vol.72 , pp. 3981-3987
    • Ganem, B.1    Franke, R.R.2
  • 65
    • 0032396955 scopus 로고    scopus 로고
    • Total asymmetric synthesis of taxol by dehydration condensation between 7-TES baccatin III and protected N-benzoylphenylisoserines prepared by enantioselective aldol reaction
    • Shiina, I.; Saitoh, K.; Fréchard-Ortuno, I.; Mukaiyama, T. Total asymmetric synthesis of taxol by dehydration condensation between 7-TES baccatin III and protected N-benzoylphenylisoserines prepared by enantioselective aldol reaction. Chem. Lett., 1998, 27, 3-4.
    • (1998) Chem. Lett , vol.27 , pp. 3-4
    • Shiina, I.1    Saitoh, K.2    Fréchard-Ortuno, I.3    Mukaiyama, T.4
  • 70
    • 83655183058 scopus 로고    scopus 로고
    • Scalable enantioselective total synthesis of taxanes
    • Mendoza, A.; Ishihara, Y.; Baran, P.S. Scalable enantioselective total synthesis of taxanes. Nat. Chem., 2012, 4, 21-25.
    • (2012) Nat. Chem. , vol.4 , pp. 21-25
    • Mendoza, A.1    Ishihara, Y.2    Baran, P.S.3
  • 71
    • 0031689562 scopus 로고    scopus 로고
    • Prospecting for potentially new pharmaceuticals from natural sources
    • Pandey, R.C. Prospecting for potentially new pharmaceuticals from natural sources. Med. Res. Rev., 1998, 18, 333-346.
    • (1998) Med. Res. Rev. , vol.18 , pp. 333-346
    • Pandey, R.C.1
  • 72
    • 45749147239 scopus 로고    scopus 로고
    • Cell culture of Taxus and paclitaxel production
    • Sun, B.X.; Zhang, G.Y.; Liu D.; Hu Z.B. Cell culture of Taxus and paclitaxel production. Plant Physiol. Commun., 1999, 35(2), 135-140.
    • (1999) Plant Physiol. Commun , vol.35 , Issue.2 , pp. 135-140
    • Sun, B.X.1    Zhang, G.Y.2    Liu, D.3    Hu, Z.B.4
  • 73
    • 34047224262 scopus 로고    scopus 로고
    • Technology progress on extraction and purification of taxol
    • Zhu, S.Q.; Tan, F.; Tang, K.X. Technology progress on extraction and purification of taxol. Chin. J. Biochem. Pharm., 2004, 25, 59-62.
    • (2004) Chin. J. Biochem. Pharm. , vol.25 , pp. 59-62
    • Zhu, S.Q.1    Tan, F.2    Tang, K.X.3
  • 74
    • 0028124322 scopus 로고
    • Extraction, purification by solidphase extraction and HPLC analysis of taxanes from ornamental Taxus needles
    • Mathina, M.J.; MacEachem G.J. Extraction, purification by solidphase extraction and HPLC analysis of taxanes from ornamental Taxus needles. J. Chromatogr. A, 1994, 679, 269-275.
    • (1994) J. Chromatogr. A , vol.679 , pp. 269-275
    • Mathina, M.J.1    Maceachem, G.J.2
  • 75
    • 0026516528 scopus 로고
    • High-speed countercurrent chromatography separation of taxol and related diterpenoids from Taxus baccata
    • Vanhaelen-Fastre, R.; Diallo, B.; Jaziri, M. High-speed countercurrent chromatography separation of taxol and related diterpenoids from Taxus baccata. J. Liq. Chromatogr., 1992, 15, 697-706.
    • (1992) J. Liq. Chromatogr. , vol.15 , pp. 697-706
    • Vanhaelen-Fastre, R.1    Diallo, B.2    Jaziri, M.3
  • 76
    • 85010678215 scopus 로고    scopus 로고
    • The establishment of extraction method of taxol from Taxus brevifolia
    • Wang, X.J.; Zhang, W.; Wang, J. The establishment of extraction method of taxol from Taxus brevifolia. Lett. Biotechnol., 2007, 18, 2789-2791.
    • (2007) Lett. Biotechnol. , vol.18 , pp. 2789-2791
    • Wang, X.J.1    Zhang, W.2    Wang, J.3
  • 77
    • 0001651240 scopus 로고
    • Highperformance liquid chromatographic assay of taxol
    • Richheimer, S.L.; Tinnermeier, D.M.; Timmons, D.W. Highperformance liquid chromatographic assay of taxol. Anal. Chem., 1992, 64, 2323-2326.
    • (1992) Anal. Chem. , vol.64 , pp. 2323-2326
    • Richheimer, S.L.1    Tinnermeier, D.M.2    Timmons, D.W.3
  • 78
    • 79955085861 scopus 로고    scopus 로고
    • Efficient purification of paclitaxel from yews using high-performance displacement chromatography technique
    • Watchueng, J.; Kamnaing, P.; Gao, J.M.; Kiyota, T.; Yeboah, F.; Konishi, Y. Efficient purification of paclitaxel from yews using high-performance displacement chromatography technique. J. Chromatogr. A, 2011, 20, 2929-2935.
    • (2011) J. Chromatogr. A , vol.20 , pp. 2929-2935
    • Watchueng, J.1    Kamnaing, P.2    Gao, J.M.3    Kiyota, T.4    Yeboah, F.5    Konishi, Y.6
  • 79
    • 0027258058 scopus 로고
    • Rapid isocratic reversed phase HPLC of taxanes on new columns developed specifically for taxol analysis
    • Ketchum, R.E.B.; Bibson, D.M. Rapid isocratic reversed phase HPLC of taxanes on new columns developed specifically for taxol analysis. J. Liq. Chromatogr., 1993, 16, 2519-2530.
    • (1993) J. Liq. Chromatogr. , vol.16 , pp. 2519-2530
    • Ketchum, R.E.B.1    Bibson, D.M.2
  • 80
    • 0026592986 scopus 로고
    • Determination of taxol by liquid chromatography-thermospray mass spectrometry
    • Auriola, S.O.K.; Lepistö, A.M.; Naaranlahti, T.; Lapinjoki, S.P. Determination of taxol by liquid chromatography-thermospray mass spectrometry. J. Chromatogr. A, 1992, 594, 153-158.
    • (1992) J. Chromatogr. A , vol.594 , pp. 153-158
    • Auriola, S.O.K.1    Lepistö, A.M.2    Naaranlahti, T.3    Lapinjoki, S.P.4
  • 81
    • 0027258316 scopus 로고
    • Analysis of taxol and related diterpenoids from cell cultures by liquid chromatography-electrospray mass spectrometry
    • Bitsch, F.; Ma, W.; Macdonald, F.; Nieder, M.; Shackleton, C.H. Analysis of taxol and related diterpenoids from cell cultures by liquid chromatography-electrospray mass spectrometry. J. Chromatogr. A, 1993, 615, 272-280.
    • (1993) J. Chromatogr. A , vol.615 , pp. 272-280
    • Bitsch, F.1    Ma, W.2    Macdonald, F.3    Nieder, M.4    Shackleton, C.H.5
  • 82
    • 84908667971 scopus 로고    scopus 로고
    • Extraction and RP-HPLC determination of taxol in rat plasma, cell culture and quality control samples
    • Tekade, R.K.; D'Emanuele, A.; Elhissi, A.; Agrawal, A.; Jain, A.; Arafat, B.T.; Jain, N.K. Extraction and RP-HPLC determination of taxol in rat plasma, cell culture and quality control samples. J. Biomed. Res., 2013, 27, 394-405.
    • (2013) J. Biomed. Res. , vol.27 , pp. 394-405
    • Tekade, R.K.1    D'emanuele, A.2    Elhissi, A.3    Agrawal, A.4    Jain, A.5    Arafat, B.T.6    Jain, N.K.7
  • 83
    • 84920410433 scopus 로고    scopus 로고
    • Pharmacokinetic profile of paclitaxel in the plasma, lung, and diaphragm following intravenous or intrapleural administration in rats
    • Li, J.; Tang, J.; Li, Y.; Yu, J.; Zhang, B.; Yu, C. Pharmacokinetic profile of paclitaxel in the plasma, lung, and diaphragm following intravenous or intrapleural administration in rats. Thorac. Cancer, 2015, 6, 43-48.
    • (2015) Thorac. Cancer , vol.6 , pp. 43-48
    • Li, J.1    Tang, J.2    Li, Y.3    Yu, J.4    Zhang, B.5    Yu, C.6
  • 84
    • 84938844316 scopus 로고    scopus 로고
    • An ultrasensitive LC-MS/MS method with liquid phase extraction to determine paclitaxel in both cell culture medium and lysate promising quantification of drug nanocarriers release in vitro
    • Baati, T.; Schembri, T.; Villard, C.; Correard, F.; Braguer, D.; Estève, M.A. An ultrasensitive LC-MS/MS method with liquid phase extraction to determine paclitaxel in both cell culture medium and lysate promising quantification of drug nanocarriers release in vitro. J. Pharm. Biomed. Anal., 2015, 115, 300-306.
    • (2015) J. Pharm. Biomed. Anal. , vol.115 , pp. 300-306
    • Baati, T.1    Schembri, T.2    Villard, C.3    Correard, F.4    Braguer, D.5    Estève, M.A.6
  • 85
    • 84901452335 scopus 로고    scopus 로고
    • Rapid and sensitive liquid chromatography coupled with electrospray ionization tandem mass spectrometry method for the analysis of paclitaxel, docetaxel, vinblastine, and vinorelbine in human plasma
    • Gao, S.; Zhou, J.; Zhang, F.; Miao, H. ;Yun, Y.; Feng, J.; Tao, X.; Chen, W. Rapid and sensitive liquid chromatography coupled with electrospray ionization tandem mass spectrometry method for the analysis of paclitaxel, docetaxel, vinblastine, and vinorelbine in human plasma. Ther. Drug Monit., 2014, 36, 394-400.
    • (2014) Ther. Drug Monit. , vol.36 , pp. 394-400
    • Gao, S.1    Zhou, J.2    Zhang, F.3    Miao, H.4    Yun, Y.5    Feng, J.6    Tao, X.7    Chen, W.8
  • 86
    • 84982142298 scopus 로고    scopus 로고
    • A smear method for measuring anti-cancer drugs residues in hospitals
    • Takano, T.; Suzuki, S.; Tsukiyama, I.; Saito, H. A smear method for measuring anti-cancer drugs residues in hospitals. Sangyo Eiseigaku Zasshi., 2015, doi: 10.1539/sangyoeisei.B15004.
    • (2015) Sangyo Eiseigaku Zasshi.
    • Takano, T.1    Suzuki, S.2    Tsukiyama, I.3    Saito, H.4
  • 88
    • 0028861177 scopus 로고
    • Characterization of the taxol binding site on the microtubule. 2-(m-azidobenzoyl) taxol photolabels a peptide (amino acids 217-231) of beta-tubulin
    • Rao, S.; Orr, G.A.; Chaudhary, A.G.; Kingston, D.G.I.; Horwitz, S.B. Characterization of the taxol binding site on the microtubule. 2-(m-azidobenzoyl) taxol photolabels a peptide (amino acids 217-231) of beta-tubulin. J. Biol. Chem., 1995, 270, 20235-20238.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20235-20238
    • Rao, S.1    Orr, G.A.2    Chaudhary, A.G.3    Kingston, D.G.I.4    Horwitz, S.B.5
  • 89
    • 1842486792 scopus 로고    scopus 로고
    • The spindle checkpoint, aneuploidy, and cancer
    • Bharadwaj, R.; Yu, H. The spindle checkpoint, aneuploidy, and cancer. Oncogene, 2004, 23, 2016-2027.
    • (2004) Oncogene , vol.23 , pp. 2016-2027
    • Bharadwaj, R.1    Yu, H.2
  • 90
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan, M.A.; Wilson, L. Microtubules as a target for anticancer drugs. Nat. Rev. Cancer, 2004, 4, 253-265.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 91
    • 50249090443 scopus 로고    scopus 로고
    • Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied
    • Brito, D.A.; Yang, Z.; Rieder, C.L. Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied. J. Cell. Biol., 2008, 182, 623-629.
    • (2008) J. Cell. Biol. , vol.182 , pp. 623-629
    • Brito, D.A.1    Yang, Z.2    Rieder, C.L.3
  • 92
    • 77953533803 scopus 로고    scopus 로고
    • Targeting apoptosis pathway with natural terpenoids: Implications for treatment of breast and prostate cancer
    • Yang, H.; Dou, Q.P. Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer. Curr. Drug Targets, 2010, 11, 733-744.
    • (2010) Curr. Drug Targets , vol.11 , pp. 733-744
    • Yang, H.1    Dou, Q.P.2
  • 93
    • 33645402536 scopus 로고    scopus 로고
    • Danshen: A popular Chinese cardiac herbal drug
    • Cheng, T.O. Danshen: a popular Chinese cardiac herbal drug. J. Am. Coll. Cardiol., 2006, 47(7), 1498.
    • (2006) J. Am. Coll. Cardiol. , vol.47 , Issue.7 , pp. 1498
    • Cheng, T.O.1
  • 95
    • 79953121603 scopus 로고    scopus 로고
    • Diterpenoid tanshinones and phenolic acids from cultured hairy roots of Salvia miltiorrhiza Bunge and their antimicrobial activities
    • Zhao, J.; Lou, J.; Mou, Y.; Li, P.; Wu, J.; Zhou, L. Diterpenoid tanshinones and phenolic acids from cultured hairy roots of Salvia miltiorrhiza Bunge and their antimicrobial activities. Molecules, 2011, 16, 2259-2267.
    • (2011) Molecules , vol.16 , pp. 2259-2267
    • Zhao, J.1    Lou, J.2    Mou, Y.3    Li, P.4    Wu, J.5    Zhou, L.6
  • 96
    • 85018214919 scopus 로고    scopus 로고
    • Establishment of an interleukin-1β-induced inflammation-activated endothelial cell smooth muscle cell-mononuclear cell co-culture model and evaluation of the anti-inflammatory effects of tanshinone IIA on atherosclerosis
    • Li, Y.; Guo, Y.; Chen, Y.; Wang, Y.; You, Y.; Yang, Q.; Weng, X.; Li, Q.; Zhu, X.; Zhou, B.; Liu, X.; Gong, Z.; Zhang, R. Establishment of an interleukin-1β-induced inflammation-activated endothelial cell smooth muscle cell-mononuclear cell co-culture model and evaluation of the anti-inflammatory effects of tanshinone IIA on atherosclerosis. Mol. Med. Rep., 2015, 12, 1665-1676.
    • (2015) Mol. Med. Rep. , vol.12 , pp. 1665-1676
    • Li, Y.1    Guo, Y.2    Chen, Y.3    Wang, Y.4    You, Y.5    Yang, Q.6    Weng, X.7    Li, Q.8    Zhu, X.9    Zhou, B.10    Liu, X.11    Gong, Z.12    Zhang, R.13
  • 97
    • 85010643439 scopus 로고    scopus 로고
    • Protective effects of tanshinone IIA on myocardial ischemia reperfusion injury by reducing oxidative stress, HMGB1 expression, and inflammatory reaction
    • Hu, H.; Zhai, C.; Qian, G.; Gu, A.; Liu, J.; Ying, F.; Xu, W.; Jin, D.; Wang, H.; Hu, H.; Zhang, Y.; Tang, G. Protective effects of tanshinone IIA on myocardial ischemia reperfusion injury by reducing oxidative stress, HMGB1 expression, and inflammatory reaction. Pharm. Biol., 2015, 13, 1-7.
    • (2015) Pharm. Biol. , vol.13 , pp. 1-7
    • Hu, H.1    Zhai, C.2    Qian, G.3    Gu, A.4    Liu, J.5    Ying, F.6    Xu, W.7    Jin, D.8    Wang, H.9    Hu, H.10    Zhang, Y.11    Tang, G.12
  • 98
    • 45349100259 scopus 로고    scopus 로고
    • Effects of tanshinone IIA on proliferation, migration and adhesion of endothelial progenitor cells from peripheral blood. Chin
    • Chen, X.F.; Tang, L.J.; Zhu, M.; Gu, Z.L.; Jiang, J.J.; Du, Y.X. Effects of tanshinone IIA on proliferation, migration and adhesion of endothelial progenitor cells from peripheral blood. Chin. Pharmacol. Bull., 2007, 23, 274-275.
    • (2007) Pharmacol. Bull. , vol.23 , pp. 274-275
    • Chen, X.F.1    Tang, L.J.2    Zhu, M.3    Gu, Z.L.4    Jiang, J.J.5    Du, Y.X.6
  • 99
    • 27844511101 scopus 로고    scopus 로고
    • Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
    • Zhou, L.; Zuo, Z.; Chow, M.S. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J. Clin. Pharmacol., 2005, 45, 1345-1359.
    • (2005) J. Clin. Pharmacol. , vol.45 , pp. 1345-1359
    • Zhou, L.1    Zuo, Z.2    Chow, M.S.3
  • 100
    • 0034729274 scopus 로고    scopus 로고
    • Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HePG2 cells
    • Liu, J.; Shen, H.M.; Ong, C.N. Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HePG2 cells. Cancer Lett., 2000, 153, 85-93.
    • (2000) Cancer Lett. , vol.153 , pp. 85-93
    • Liu, J.1    Shen, H.M.2    Ong, C.N.3
  • 101
    • 1842687272 scopus 로고    scopus 로고
    • Protective effect of tanshinone IIA for liver injury in mice
    • Liu, Y.G.; Chen, H.C.; Jiang, Y.P.; Li, F.Z. Protective effect of tanshinone IIA for liver injury in mice. Chin. Med. Mater., 2001, 24, 588-589.
    • (2001) Chin. Med. Mater. , vol.24 , pp. 588-589
    • Liu, Y.G.1    Chen, H.C.2    Jiang, Y.P.3    Li, F.Z.4
  • 103
    • 2442482979 scopus 로고    scopus 로고
    • Ketosalvia miltiorrhiza preventing postmenopausal osteoporosis
    • Li, L.; Zhou, Y.; Shao, X.; Liu, Y.; Wang, L.; Wang, D. Ketosalvia miltiorrhiza preventing postmenopausal osteoporosis. Chin. J. Osteoporos., 1996, 2, 78-80.
    • (1996) Chin. J. Osteoporos. , vol.2 , pp. 78-80
    • Li, L.1    Zhou, Y.2    Shao, X.3    Liu, Y.4    Wang, L.5    Wang, D.6
  • 104
    • 70749152711 scopus 로고    scopus 로고
    • A functional genomics approach to tanshinone biosynthesis provides stereochemical insights
    • Gao, W.; Hillwig, M.L.; Huang, L.; Cui, G.; Wang, X.; Kong, J.; Yang, B.; Peters, R.J. A functional genomics approach to tanshinone biosynthesis provides stereochemical insights. Org. Lett., 2009, 11, 5170-5173.
    • (2009) Org. Lett , vol.11 , pp. 5170-5173
    • Gao, W.1    Hillwig, M.L.2    Huang, L.3    Cui, G.4    Wang, X.5    Kong, J.6    Yang, B.7    Peters, R.J.8
  • 106
    • 79960936837 scopus 로고    scopus 로고
    • Candidate genes involved in tanshinone biosynthesis in hairy roots of Salvia miltiorrhiza revealed by cDNA microarray
    • Cui, G.; Huang, L.; Tang, X.; Zhao J. Candidate genes involved in tanshinone biosynthesis in hairy roots of Salvia miltiorrhiza revealed by cDNA microarray. Mol. Biol. Rep., 2011, 38, 2471-2478.
    • (2011) Mol. Biol. Rep. , vol.38 , pp. 2471-2478
    • Cui, G.1    Huang, L.2    Tang, X.3    Zhao, J.4
  • 107
    • 84894207903 scopus 로고    scopus 로고
    • Transcriptome analysis of medicinal plant Salvia miltiorrhiza and identification of genes related to tanshinone biosynthesis
    • Yang, L.; Ding, G.; Lin, H.; Cheng, H.; Kong, Y.; Wei, Y.; Fang, X.; Liu, R.; Wang, L.; Chen, X.; Yang, C. Transcriptome analysis of medicinal plant Salvia miltiorrhiza and identification of genes related to tanshinone biosynthesis. PLoS One, 2013, 8: e80464.
    • (2013) Plos One , vol.8
    • Yang, L.1    Ding, G.2    Lin, H.3    Cheng, H.4    Kong, Y.5    Wei, Y.6    Fang, X.7    Liu, R.8    Wang, L.9    Chen, X.10    Yang, C.11
  • 109
    • 84908205786 scopus 로고    scopus 로고
    • Transcriptional data mining of Salvia miltiorrhiza in response to methyl jasmonate to examine the mechanism of bioactive compound biosynthesis and regulation
    • Luo, H.; Zhu, Y.; Song, J.; Xu, L.; Sun, C.; Zhang, X.; Xu, Y.; He, L.; Sun, W.; Xu, H.; Wang, B.; Li, X.; Li, C.; Liu, J.; Chen, S. Transcriptional data mining of Salvia miltiorrhiza in response to methyl jasmonate to examine the mechanism of bioactive compound biosynthesis and regulation. Physiol. Plant., 2014, 152, 241-255.
    • (2014) Physiol. Plant. , vol.152 , pp. 241-255
    • Luo, H.1    Zhu, Y.2    Song, J.3    Xu, L.4    Sun, C.5    Zhang, X.6    Xu, Y.7    He, L.8    Sun, W.9    Xu, H.10    Wang, B.11    Li, X.12    Li, C.13    Liu, J.14    Chen, S.15
  • 110
    • 84930872190 scopus 로고    scopus 로고
    • Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis
    • Xu, Z.; Peters, R.J.; Weirather, J.; Luo, H.; Liao, B.; Zhang, X.; Zhu, Y.; Ji, A.; Zhang, B.; Hu, S.; Au, K.F.; Song, J.; Chen, S. Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis. Plant J., 2015, 82, 951-961.
    • (2015) Plant J. , vol.82 , pp. 951-961
    • Xu, Z.1    Peters, R.J.2    Weirather, J.3    Luo, H.4    Liao, B.5    Zhang, X.6    Zhu, Y.7    Ji, A.8    Zhang, B.9    Hu, S.10    Au, K.F.11    Song, J.12    Chen, S.13
  • 112
    • 84925341689 scopus 로고    scopus 로고
    • Molecular cloning and expression analysis of WRKY transcription factor genes in Salvia miltiorrhiza
    • Li, C.; Li, D.; Shao, F.; Lu, S. Molecular cloning and expression analysis of WRKY transcription factor genes in Salvia miltiorrhiza. BMC Genomics, 2015, 16, 200.
    • (2015) BMC Genomics , vol.16 , pp. 200
    • Li, C.1    Li, D.2    Shao, F.3    Lu, S.4
  • 113
    • 84899478214 scopus 로고    scopus 로고
    • Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors shows the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza
    • Li, C.; Lu, S. Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors shows the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza. BMC Genomics, 2014, 15, 277.
    • (2014) BMC Genomics , vol.15 , pp. 277
    • Li, C.1    Lu, S.2
  • 114
    • 84892485758 scopus 로고    scopus 로고
    • Genome-wide analysis and molecular dissection of the SPL gene family in Salvia miltiorrhiza
    • Zhang, L.; Wu, B.; Zhao, D.; Li, C.; Shao, F.; Lu, S. Genome-wide analysis and molecular dissection of the SPL gene family in Salvia miltiorrhiza. J. Integr. Plant Biol., 2014, 56, 38-50.
    • (2014) J. Integr. Plant Biol. , vol.56 , pp. 38-50
    • Zhang, L.1    Wu, B.2    Zhao, D.3    Li, C.4    Shao, F.5    Lu, S.6
  • 115
    • 84929330004 scopus 로고    scopus 로고
    • Comparative analysis of the Dicer-like gene family reveals loss of miR162 target site in SmDCL1 from Salvia miltiorrhiza
    • Shao, F.; Qiu, D.; Lu, S. Comparative analysis of the Dicer-like gene family reveals loss of miR162 target site in SmDCL1 from Salvia miltiorrhiza. Sci. Rep., 2015, 5, 9891.
    • (2015) Sci. Rep. , vol.5 , pp. 9891
    • Shao, F.1    Qiu, D.2    Lu, S.3
  • 116
    • 84939961211 scopus 로고    scopus 로고
    • Identification and characterization of mRNA-like noncoding RNAs in Salvia miltiorrhiza
    • Li, D.; Shao, F.; Lu, S. Identification and characterization of mRNA-like noncoding RNAs in Salvia miltiorrhiza. Planta, 2015, 241, 1131-1143.
    • (2015) Planta , vol.241 , pp. 1131-1143
    • Li, D.1    Shao, F.2    Lu, S.3
  • 117
    • 84899635010 scopus 로고    scopus 로고
    • Identification, molecular cloning and expression analysis of five RNA-dependent RNA polymerase genes in Salvia miltiorrhiza
    • Shao, F.; Lu, S. Identification, molecular cloning and expression analysis of five RNA-dependent RNA polymerase genes in Salvia miltiorrhiza. PLoS One, 2014, 9, e95117.
    • (2014) Plos One , vol.9
    • Shao, F.1    Lu, S.2
  • 118
    • 84880883780 scopus 로고    scopus 로고
    • Genome-wide identification, molecular cloning, expression profiling and posttranscriptional regulation analysis of the Argonaute gene family in Salvia miltiorrhiza, an emerging model medicinal plant
    • Shao, F.; Lu, S. Genome-wide identification, molecular cloning, expression profiling and posttranscriptional regulation analysis of the Argonaute gene family in Salvia miltiorrhiza, an emerging model medicinal plant. BMC Genomics, 2013, 14, 512.
    • (2013) BMC Genomics , vol.14 , pp. 512
    • Shao, F.1    Lu, S.2
  • 119
    • 84937043187 scopus 로고    scopus 로고
    • Genome-wide characterisation and analysis of bHLH transcription factors related to tanshinone biosynthesis in Salvia miltiorrhiza
    • Zhang, X.; Luo, H.; Xu, Z.; Zhu, Y.; Ji, A.; Song, J.; Chen, S. Genome-wide characterisation and analysis of bHLH transcription factors related to tanshinone biosynthesis in Salvia miltiorrhiza. Sci. Rep., 2015, 5, 11244.
    • (2015) Sci. Rep. , vol.5
    • Zhang, X.1    Luo, H.2    Xu, Z.3    Zhu, Y.4    Ji, A.5    Song, J.6    Chen, S.7
  • 120
    • 0013189859 scopus 로고
    • On the the chemical composition of Salvia miltiorrhiza (Chinese drug Tan-shen)
    • Nakao, M.; Fukushima, T. On the the chemical composition of Salvia miltiorrhiza (Chinese drug Tan-shen). Yakugaku Zasshi, 1934, 54, 844-858.
    • (1934) Yakugaku Zasshi , vol.54 , pp. 844-858
    • Nakao, M.1    Fukushima, T.2
  • 121
    • 33745783431 scopus 로고    scopus 로고
    • Determination of danshensu, tanshinone IIA, dihydrotanshinone I and cryptotanshinone in Salvia miltiorrhiza Bge. By HPLC
    • Zheng, X.; Dong, S.; Feng, W. Determination of danshensu, tanshinone IIA, dihydrotanshinone I and cryptotanshinone in Salvia miltiorrhiza Bge. by HPLC. Chin. J. Exp. Tradit. Med. Formulae, 2003, 9(6), 12-15.
    • (2003) Chin. J. Exp. Tradit. Med. Formulae , vol.9 , Issue.6 , pp. 12-15
    • Zheng, X.1    Dong, S.2    Feng, W.3
  • 123
    • 33646490711 scopus 로고    scopus 로고
    • Fingerprinting of Salvia miltiorrhiza Bunge by thin-layer chromatography scan compared with high speed countercurrent chromatography
    • Gu, M.; Su, Z.; Ouyang, F. Fingerprinting of Salvia miltiorrhiza Bunge by thin-layer chromatography scan compared with high speed countercurrent chromatography. J. Liq. Chromatogr. Relat. Technol., 2006, 29, 1503-1514.
    • (2006) J. Liq. Chromatogr. Relat. Technol. , vol.29 , pp. 1503-1514
    • Gu, M.1    Su, Z.2    Ouyang, F.3
  • 124
    • 84880778224 scopus 로고    scopus 로고
    • Effects of combined elicitors on tanshinone metabolic profiling and SmCPS expression in Salvia miltiorrhiza hairy root cultures
    • Cheng, Q.; He, Y.; Li, G.; Liu, Y.; Gao, W.; Huang, L. Effects of combined elicitors on tanshinone metabolic profiling and SmCPS expression in Salvia miltiorrhiza hairy root cultures. Molecules, 2013, 18, 7473-7485.
    • (2013) Molecules , vol.18 , pp. 7473-7485
    • Cheng, Q.1    He, Y.2    Li, G.3    Liu, Y.4    Gao, W.5    Huang, L.6
  • 125
    • 33645840150 scopus 로고    scopus 로고
    • Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry
    • Yang, M.; Liu, A.; Guan, S.; Sun, J.; Xu, M.; Guo, D. Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2006, 20, 1266-1280
    • (2006) Rapid Commun. Mass Spectrom. , vol.20 , pp. 1266-1280
    • Yang, M.1    Liu, A.2    Guan, S.3    Sun, J.4    Xu, M.5    Guo, D.6
  • 126
    • 34250786764 scopus 로고    scopus 로고
    • Rapid separation and identification of phenolic and diterpenoid constituents from Radix Salvia miltiorrhizae by high-performance liquid chromatography diode-array detection, electrospray ionization time-of-flight mass spectrometry and electrospray ionization quadrupole ion trap mass spectrometry
    • Zhu, Z.; Zhang, H.; Zhao, L.; Dong, X.; Li, X.; Chai, Y.; Zhang, G. Rapid separation and identification of phenolic and diterpenoid constituents from Radix Salvia miltiorrhizae by high-performance liquid chromatography diode-array detection, electrospray ionization time-of-flight mass spectrometry and electrospray ionization quadrupole ion trap mass spectrometry. Rapid Commun. Mass Spectrom., 2007, 21, 1855-1865.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , pp. 1855-1865
    • Zhu, Z.1    Zhang, H.2    Zhao, L.3    Dong, X.4    Li, X.5    Chai, Y.6    Zhang, G.7
  • 127
    • 80955181057 scopus 로고    scopus 로고
    • Extraction and preparative purification of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography
    • Sun, A.; Zhang, Y.; Li, A.; Meng, Z.; Liu, R. Extraction and preparative purification of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography. J. Chromatogr. B, 2011, 879, 1899-1904.
    • (2011) J. Chromatogr. B , vol.879 , pp. 1899-1904
    • Sun, A.1    Zhang, Y.2    Li, A.3    Meng, Z.4    Liu, R.5
  • 128
    • 84861166372 scopus 로고    scopus 로고
    • Modeling gradient elution in countercurrent chromatography: Efficient separation of tanshinones from Salvia miltiorrhiza Bunge
    • Wu, S.; Wu, D.; Liang, J.; Berthod, A. Modeling gradient elution in countercurrent chromatography: Efficient separation of tanshinones from Salvia miltiorrhiza Bunge. J. Sep. Sci., 2012, 35, 964-976.
    • (2012) J. Sep. Sci. , vol.35 , pp. 964-976
    • Wu, S.1    Wu, D.2    Liang, J.3    Berthod, A.4
  • 129
    • 4544376366 scopus 로고    scopus 로고
    • Chemistry and biology of terpene trilactones from Ginkgo biloba
    • Strømgaard, K.; Nakanishi, K. Chemistry and biology of terpene trilactones from Ginkgo biloba. Angew. Chem. Int. Ed., 2004, 43, 1640-1658.
    • (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 1640-1658
    • Strømgaard, K.1    Nakanishi, K.2
  • 130
    • 0000716790 scopus 로고
    • BN 52021 and related compounds: A new series of highly specific PAF-acether antagonists isolated from Ginkgo biloba
    • Braquet, P.; Spinnewyn, B.; Braquet, M.; Bourgain, R.H.; Taylor, J.E.; Etienne, A.; Drieu, K. BN 52021 and related compounds: a new series of highly specific PAF-acether antagonists isolated from Ginkgo biloba. Blood Vessels, 1985, 16, 559-572.
    • (1985) Blood Vessels , vol.16 , pp. 559-572
    • Braquet, P.1    Spinnewyn, B.2    Braquet, M.3    Bourgain, R.H.4    Taylor, J.E.5    Etienne, A.6    Drieu, K.7
  • 131
    • 0023212249 scopus 로고
    • The ginkgolides: Potent platelet-activating factor antagonists isolated from Ginkgo biloba leaves: Chemistry, pharmacology and clinical applications
    • Braquet, P. The ginkgolides: potent platelet-activating factor antagonists isolated from Ginkgo biloba leaves: chemistry, pharmacology and clinical applications. Drugs Fut., 1987, 12, 643-699.
    • (1987) Drugs Fut. , vol.12 , pp. 643-699
    • Braquet, P.1
  • 132
    • 0036524316 scopus 로고    scopus 로고
    • Effects of Ginkgo biloba extract constituents on glycine-activated strychnine-sensitive receptors in hippocampal pyramidal neurons of the rat
    • Kondratskaya E.L., Krishtal O.A. Effects of Ginkgo biloba extract constituents on glycine-activated strychnine-sensitive receptors in hippocampal pyramidal neurons of the rat. Neurophysiology, 2002, 34, 155-157.
    • (2002) Neurophysiology , vol.34 , pp. 155-157
    • Kondratskaya, E.L.1    Krishtal, O.A.2
  • 133
    • 0030458395 scopus 로고    scopus 로고
    • In vivo regulation of peripheral-type benzodiazepine receptor and glucocorticoid synthesis by Ginkgo biloba extract EGb 761 and isolated ginkgolides
    • Amri, H.; Ogwuegbu, S.O.; Boujrad, N.; Drieu, K.; Papadopoulos, V. In vivo regulation of peripheral-type benzodiazepine receptor and glucocorticoid synthesis by Ginkgo biloba extract EGb 761 and isolated ginkgolides. Endocrinology, 1996, 137, 5707-5718.
    • (1996) Endocrinology , vol.137 , pp. 5707-5718
    • Amri, H.1    Ogwuegbu, S.O.2    Boujrad, N.3    Drieu, K.4    Papadopoulos, V.5
  • 134
    • 2242436971 scopus 로고    scopus 로고
    • Use of ginkgolide B and a ginkgolide-activated response element to control gene transcription: Example of the adrenocortical peripheral-type benzodiazepine receptor
    • Amri, H.; Drieu, K.; Papadopoulos, V. Use of ginkgolide B and a ginkgolide-activated response element to control gene transcription: example of the adrenocortical peripheral-type benzodiazepine receptor. Cell. Mol. Biol., 2002, 48, 633-639.
    • (2002) Cell. Mol. Biol. , vol.48 , pp. 633-639
    • Amri, H.1    Drieu, K.2    Papadopoulos, V.3
  • 135
    • 20044384736 scopus 로고    scopus 로고
    • Inhibitory effect of ginkgolide B on angiogenesis in chronic inflammation
    • Ou-Yang, X.Y.; Wang, W.J.; Liao, W.H.; Chen, X.H. Inhibitory effect of ginkgolide B on angiogenesis in chronic inflammation. Yao Xue Xue Bao, 2005, 40, 311-315.
    • (2005) Yao Xue Xue Bao , vol.40 , pp. 311-315
    • Ou-Yang, X.Y.1    Wang, W.J.2    Liao, W.H.3    Chen, X.H.4
  • 136
    • 80053224180 scopus 로고    scopus 로고
    • A novel anti-inflammatory role for ginkgolide B in asthma via inhibition of ERK/MAPK signaling pathway
    • Chu, X.; Ci, X.; He, J. A novel anti-inflammatory role for ginkgolide B in asthma via inhibition of ERK/MAPK signaling pathway. Molecules, 2011, 16, 7634-7648.
    • (2011) Molecules , vol.16 , pp. 7634-7648
    • Chu, X.1    Ci, X.2    He, J.3
  • 137
    • 84900427464 scopus 로고    scopus 로고
    • Phytochemical and medicinal importance of Ginkgo biloba L
    • Mohantaa, T.K.; Tambolib, Y.; Zubaidhab, P.K. Phytochemical and medicinal importance of Ginkgo biloba L. Nat. Prod. Res., 2014, 28, 746-752.
    • (2014) Nat. Prod. Res. , vol.28 , pp. 746-752
    • Mohantaa, T.K.1    Tambolib, Y.2    Zubaidhab, P.K.3
  • 138
    • 0141749421 scopus 로고    scopus 로고
    • Neuroprotective effects of Ginkgo biloba extract
    • Ahlemeyer, B.; Krieglstein, J. Neuroprotective effects of Ginkgo biloba extract. Cell. Mol. Life Sci., 2003, 60, 1779-1792.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 1779-1792
    • Ahlemeyer, B.1    Krieglstein, J.2
  • 139
    • 84856237050 scopus 로고    scopus 로고
    • Different neuroprotective responses of ginkgolide B and bilobalide, the two Ginkgo components, in ischemic rats with hyperglycemia
    • Huang, M.; Qian, Y.; Guan, T.; Huang, L.; Tang, X.; Li, Y. Different neuroprotective responses of ginkgolide B and bilobalide, the two Ginkgo components, in ischemic rats with hyperglycemia. Eur. J. Pharmacol., 2012, 677, 71-76.
    • (2012) Eur. J. Pharmacol. , vol.677 , pp. 71-76
    • Huang, M.1    Qian, Y.2    Guan, T.3    Huang, L.4    Tang, X.5    Li, Y.6
  • 140
    • 0032076142 scopus 로고    scopus 로고
    • Distribution of ginkgolides and terpenoid biosynthetic activity in Ginkgo biloba
    • Carrier, D.J.; Van Beek, T.; Van Der Heijden, R.; Verpoorte, R. Distribution of ginkgolides and terpenoid biosynthetic activity in Ginkgo biloba. Phytochemistry, 1998, 48, 89-92.
    • (1998) Phytochemistry , vol.48 , pp. 89-92
    • Carrier, D.J.1    Van Beek, T.2    Van Der Heijden, R.3    Verpoorte, R.4
  • 141
    • 0030838208 scopus 로고    scopus 로고
    • Ginkgolide and bilobalide biosynthesis in Ginkgo biloba. I. Sites of synthesis, translocation and accumulation of ginkolides and bilobalide
    • Cartayrade, A.; Neau, E.; Sohier, C.; Balz, J.P.; Carde, J.P.; Walter, J. Ginkgolide and bilobalide biosynthesis in Ginkgo biloba. I. Sites of synthesis, translocation and accumulation of ginkolides and bilobalide. Plant Physiol. Biochem., 1997, 35, 859-868.
    • (1997) Plant Physiol. Biochem , vol.35 , pp. 859-868
    • Cartayrade, A.1    Neau, E.2    Sohier, C.3    Balz, J.P.4    Carde, J.P.5    Walter, J.6
  • 142
    • 0004646216 scopus 로고
    • Biosynthesis of ginkgolide B, its diterpenoid nature, and origin of the tert-butyl group
    • Nakanishi, K.; Habaguchi, K. Biosynthesis of ginkgolide B, its diterpenoid nature, and origin of the tert-butyl group. J. Am. Chem. Soc., 1971, 93, 3546-3547.
    • (1971) J. Am. Chem. Soc. , vol.93 , pp. 3546-3547
    • Nakanishi, K.1    Habaguchi, K.2
  • 143
    • 0035881523 scopus 로고    scopus 로고
    • Cloning and characterization of Ginkgo biloba levopimaradiene synthase which catalyzes the first committed step in ginkgolide biosynthesis.
    • Schepmann, H.G.; Pang, J.; Matsuda, S.P. Cloning and characterization of Ginkgo biloba levopimaradiene synthase which catalyzes the first committed step in ginkgolide biosynthesis. Arch. Biochem. Biophys., 2001, 392, 263-269.
    • (2001) Arch. Biochem. Biophys. , vol.392 , pp. 263-269
    • Schepmann, H.G.1    Pang, J.2    Matsuda, S.P.3
  • 144
    • 84906221942 scopus 로고    scopus 로고
    • Advances in Ginkgo biloba research: Genomics and metabolomics perspectives
    • Mohanta, T.K. Advances in Ginkgo biloba research: Genomics and metabolomics perspectives. Afr. J. Biotechnol., 2012, 11, 15936-15944.
    • (2012) Afr. J. Biotechnol. , vol.11 , pp. 15936-15944
    • Mohanta, T.K.1
  • 145
    • 84879630202 scopus 로고    scopus 로고
    • Biosynthesis pathways of ginkgolides.
    • Zeng, Z.; Zhu, J.; Chen, L.; Wen, W.; Yu, R. Biosynthesis pathways of ginkgolides. Pharmacogn. Rev., 2013, 7(13), 47-52.
    • (2013) Pharmacogn. Rev. , vol.7 , Issue.13 , pp. 47-52
    • Zeng, Z.1    Zhu, J.2    Chen, L.3    Wen, W.4    Yu, R.5
  • 146
    • 14344257095 scopus 로고    scopus 로고
    • van Beek, T.A. Ed. Harwood Academic Publishers: Amsterdam
    • Oreilly, J. In: Ginkgo biloba; van Beek, T.A. Ed. Harwood Academic Publishers: Amsterdam, 2000; Vol. 12, pp. 99-108.
    • (2000) Ginkgo Biloba , vol.12 , pp. 99-108
    • Oreilly, J.1
  • 147
    • 14344256045 scopus 로고    scopus 로고
    • Isolation of ginkgolides A, B, C, J and bilobalide from G. Biloba extracts
    • Jaracz, S.; Malik, S.; Nakanishi, K. Isolation of ginkgolides A, B, C, J and bilobalide from G. biloba extracts. Phytochemistry, 2004, 65, 2897-2902.
    • (2004) Phytochemistry , vol.65 , pp. 2897-2902
    • Jaracz, S.1    Malik, S.2    Nakanishi, K.3
  • 148
    • 85010697195 scopus 로고    scopus 로고
    • HPLC-RI determination of four ginkgolides in Ginkgo biloba extracts
    • Yuan, C.; Pan, J.; Hu, X.; Kai, G. HPLC-RI determination of four ginkgolides in Ginkgo biloba extracts. Chin. J. Pharm. Anal., 2008, 28, 739-741.
    • (2008) Chin. J. Pharm. Anal. , vol.28 , pp. 739-741
    • Yuan, C.1    Pan, J.2    Hu, X.3    Kai, G.4
  • 149
    • 84877866473 scopus 로고    scopus 로고
    • Fingerprint analysis of Ginkgo biloba extract and Ginkgo semen in preparations by LC-Q-TOF/MS
    • Luo, J.L.; Lu, F.L.; Liu, Y.C.; Shin, Y.C.; Lo, C.F. Fingerprint analysis of Ginkgo biloba extract and Ginkgo semen in preparations by LC-Q-TOF/MS. J. Food Drug Anal., 2013, 21, 27-39.
    • (2013) J. Food Drug Anal , vol.21 , pp. 27-39
    • Luo, J.L.1    Lu, F.L.2    Liu, Y.C.3    Shin, Y.C.4    Lo, C.F.5
  • 150
    • 77349104616 scopus 로고    scopus 로고
    • Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. Preparations in humans
    • Woelkart, K.; Feizlmayr, E.; Dittrich, P.; Beubler, E.; Pinl, F.; Suter, A.; Bauer, R. Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans. Phytother. Res., 2010, 24, 445-450.
    • (2010) Phytother. Res. , vol.24 , pp. 445-450
    • Woelkart, K.1    Feizlmayr, E.2    Dittrich, P.3    Beubler, E.4    Pinl, F.5    Suter, A.6    Bauer, R.7
  • 152
    • 84938360335 scopus 로고    scopus 로고
    • Semi-quantitative determination of monocarboxylate forms of ginkgolide B in plasma by UPLC-MS
    • Li, X.J.; Wang, Y.Q.; Yang, J.; Fan, X.; Wang, L.; Yang, K.; Lan, K. Semi-quantitative determination of monocarboxylate forms of ginkgolide B in plasma by UPLC-MS. Anal. Bioanal. Chem., 2015, 407, 4121-4129.
    • (2015) Anal. Bioanal. Chem. , vol.407 , pp. 4121-4129
    • Li, X.J.1    Wang, Y.Q.2    Yang, J.3    Fan, X.4    Wang, L.5    Yang, K.6    Lan, K.7
  • 153
    • 77951932747 scopus 로고    scopus 로고
    • RNA polymerase-An important molecular target of triptolide in cancer cells
    • Pan, J. RNA polymerase-An important molecular target of triptolide in cancer cells. Cancer Lett., 2010, 292, 149-152.
    • (2010) Cancer Lett. , vol.292 , pp. 149-152
    • Pan, J.1
  • 154
    • 84946474228 scopus 로고    scopus 로고
    • Triptolide inhibits lung cancer cell migration, invasion, and metastasis
    • Reno, T.A.; Kim, J.Y.; Raz, D.J. Triptolide inhibits lung cancer cell migration, invasion, and metastasis. Ann. Thorac. Surg., 2015, 100(5), 1817-1824.
    • (2015) Ann. Thorac. Surg. , vol.100 , Issue.5 , pp. 1817-1824
    • Reno, T.A.1    Kim, J.Y.2    Raz, D.J.3
  • 156
    • 84935485863 scopus 로고    scopus 로고
    • Triptolide suppresses proliferation, hypoxia-inducible
    • Ding, X.; Zhou, X.; Jiang, B.; Zhao, Q.; Zhou, G. Triptolide suppresses proliferation, hypoxia-inducible factor-1α and c-Myc expression in pancreatic cancer cells. Mol. Med. Rep., 2015, 12, 4508-4513.
    • (2015) Mol. Med. Rep. , vol.12 , pp. 4508-4513
    • Ding, X.1    Zhou, X.2    Jiang, B.3    Zhao, Q.4    Zhou, G.5
  • 159
    • 85010667496 scopus 로고    scopus 로고
    • Studies on the semi-synthesis of triptolide
    • Guo, S.; Xia Z.; Qi, Y.; Deng F. Studies on the semi-synthesis of triptolide. J. Chin. Pharm. Uni., 1999, 30, 13-15.
    • (1999) J. Chin. Pharm. Uni. , vol.30 , pp. 13-15
    • Guo, S.1    Xia, Z.2    Qi, Y.3    Deng, F.4
  • 161
    • 84910011379 scopus 로고    scopus 로고
    • Divergent total synthesis of triptolide, triptonide, tripdiolide, 16-hydroxytriptolide, and their analogues
    • Xu, H.; Tang, H.; Feng, H.; Li, Y. Divergent total synthesis of triptolide, triptonide, tripdiolide, 16-hydroxytriptolide, and their analogues. J. Org. Chem., 2014, 79, 10110-10122.
    • (2014) J. Org. Chem. , vol.79 , pp. 10110-10122
    • Xu, H.1    Tang, H.2    Feng, H.3    Li, Y.4
  • 162
    • 85010655599 scopus 로고    scopus 로고
    • A technique for extracting triptolide from Tripterygium wilfordii
    • Cheng, J.L.; Zhu, L.; Zhu, G.N.; Xu, Z.Y. A technique for extracting triptolide from Tripterygium wilfordii. Chin. J. Pesticides, 2005, 44, 316-318.
    • (2005) Chin. J. Pesticides , vol.44 , pp. 316-318
    • Cheng, J.L.1    Zhu, L.2    Zhu, G.N.3    Xu, Z.Y.4
  • 165
    • 14544268961 scopus 로고    scopus 로고
    • Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography
    • Wang, Z.; Wen, J.; Xing, J.; Guo, D. Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography. Biomed. Chromatogr., 2005, 19, 60-62.
    • (2005) Biomed. Chromatogr. , vol.19 , pp. 60-62
    • Wang, Z.1    Wen, J.2    Xing, J.3    Guo, D.4
  • 166
    • 19044370212 scopus 로고    scopus 로고
    • Fingerprint chromatogram analysis of extracts from the leaves of Tripterygium wilfordii Hook. F. By high performance liquid chromatography
    • Li, K.; Wang, S. Fingerprint chromatogram analysis of extracts from the leaves of Tripterygium wilfordii Hook. F. By high performance liquid chromatography. J. Sep. Sci., 2005, 28, 653-657.
    • (2005) J. Sep. Sci. , vol.28 , pp. 653-657
    • Li, K.1    Wang, S.2
  • 167
    • 84934766116 scopus 로고    scopus 로고
    • Renal targeted delivery of triptolide by conjugation to the fragment peptide of human serum albumin
    • Yuan, Z.X.; Wu, X.J.; Mo, J.; Wang, Y.L.; Xu, C.Q.; Lim, L.Y. Renal targeted delivery of triptolide by conjugation to the fragment peptide of human serum albumin. Eur. J. Pharm. Biopharm., 2015, 94, 363-371.
    • (2015) Eur. J. Pharm. Biopharm. , vol.94 , pp. 363-371
    • Yuan, Z.X.1    Wu, X.J.2    Mo, J.3    Wang, Y.L.4    Xu, C.Q.5    Lim, L.Y.6
  • 169
    • 84885574287 scopus 로고    scopus 로고
    • Recent advances in the molecular basis of anti-neoplastic mechanisms of oridonin
    • Tian, W.; Chen, S.Y. Recent advances in the molecular basis of anti-neoplastic mechanisms of oridonin. Chin. J. Integr. Med., 2013, 19, 315-320.
    • (2013) Chin. J. Integr. Med. , vol.19 , pp. 315-320
    • Tian, W.1    Chen, S.Y.2
  • 170
    • 0037260455 scopus 로고    scopus 로고
    • Two novel ent-kaurene diterpenoids from Isodon rubescens
    • Han, Q.B.; Jiang, B.; Zhang, J.X.; Niu, X.M.; Sun, H.D. Two novel ent-kaurene diterpenoids from Isodon rubescens. Helv. Chim. Acta, 2003, 86, 773-777.
    • (2003) Helv. Chim. Acta , vol.86 , pp. 773-777
    • Han, Q.B.1    Jiang, B.2    Zhang, J.X.3    Niu, X.M.4    Sun, H.D.5
  • 173
    • 84898780357 scopus 로고    scopus 로고
    • Preparation of freezedried long-circulation oridonin liposomes and their pharmacokinetics in rats
    • Lin, H.; Qu, C.; Yu, Y.; Tang, Y.; Sun, X. Preparation of freezedried long-circulation oridonin liposomes and their pharmacokinetics in rats. Zhejiang Da Xue Xue Bao Yi Xue Ban., 2013, 42, 638-643.
    • (2013) Zhejiang Da Xue Xue Bao Yi Xue Ban. , vol.42 , pp. 638-643
    • Lin, H.1    Qu, C.2    Yu, Y.3    Tang, Y.4    Sun, X.5
  • 174
    • 84921328529 scopus 로고    scopus 로고
    • Nanostructured lipid carriers used for oral delivery of oridonin: An effect of ligand modification on absorption
    • Zhou, X.; Zhang, X.; Ye, Y.; Zhang, T.; Wang, H.; Ma, Z.; Wu, B. Nanostructured lipid carriers used for oral delivery of oridonin: an effect of ligand modification on absorption. Int. J. Pharm., 2015, 479, 391-398.
    • (2015) Int. J. Pharm. , vol.479 , pp. 391-398
    • Zhou, X.1    Zhang, X.2    Ye, Y.3    Zhang, T.4    Wang, H.5    Ma, Z.6    Wu, B.7
  • 175
    • 84906551672 scopus 로고    scopus 로고
    • Galactosylated bovine serum albumin nanoparticles for parenteral delivery of oridonin: Tissue distribution and pharmacokinetic studies
    • Li, C.; Zhang, D.; Guo, Y.; Guo, H.; Li, T.; Hao, L.; Zheng, D.; Liu, G.; Zhang, Q. Galactosylated bovine serum albumin nanoparticles for parenteral delivery of oridonin: tissue distribution and pharmacokinetic studies. J. Microencapsul., 2014, 31, 573-578.
    • (2014) J. Microencapsul. , vol.31 , pp. 573-578
    • Li, C.1    Zhang, D.2    Guo, Y.3    Guo, H.4    Li, T.5    Hao, L.6    Zheng, D.7    Liu, G.8    Zhang, Q.9
  • 176
    • 84861468033 scopus 로고    scopus 로고
    • Biodegradable self-assembled MPEG-PCL micelles for hydrophobic oridonin delivery in vitro
    • Xue, B.; Wang, Y.; Tang, X.; Xie, P.; Wang, Y.; Luo, F.; Wu, C.; Qian, Z. Biodegradable self-assembled MPEG-PCL micelles for hydrophobic oridonin delivery in vitro. J. Biomed. Nanotechnol., 2012, 8, 80-89.
    • (2012) J. Biomed. Nanotechnol. , vol.8 , pp. 80-89
    • Xue, B.1    Wang, Y.2    Tang, X.3    Xie, P.4    Wang, Y.5    Luo, F.6    Wu, C.7    Qian, Z.8
  • 177
    • 76849089864 scopus 로고    scopus 로고
    • Increasing diterpene yield with a modular metabolic engineering system in E. Coli: Comparison of MEV and MEP isoprenoid precursor pathway engineering
    • Morrone, D.; Lowry, L.; Determan, M.K.; Hershey, D.M.; Xu, M.; Peters, R.J. Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. Appl. Microbiol. Biotechnol., 2010, 85, 1893-1906.
    • (2010) Appl. Microbiol. Biotechnol. , vol.85 , pp. 1893-1906
    • Morrone, D.1    Lowry, L.2    Determan, M.K.3    Hershey, D.M.4    Xu, M.5    Peters, R.J.6
  • 178
    • 20544472358 scopus 로고    scopus 로고
    • Current and emerging approaches for natural product biosynthesis in microbial cells
    • Watts, K.T.; Mijts, B.N.; Schmidt-Dannert, C. Current and emerging approaches for natural product biosynthesis in microbial cells. Adv. Synth. Catal., 2005, 347, 927-940.
    • (2005) Adv. Synth. Catal. , vol.347 , pp. 927-940
    • Watts, K.T.1    Mijts, B.N.2    Schmidt-Dannert, C.3
  • 180
    • 0034664686 scopus 로고    scopus 로고
    • Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L
    • Mercke, P.; Bengtsson, M.; Bouwmeester, H.J.; Posthumus, M.A.; Brodelius, P.E. Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L. Arch. Biochem. Biophys., 2000, 381, 173-180.
    • (2000) Arch. Biochem. Biophys. , vol.381 , pp. 173-180
    • Mercke, P.1    Bengtsson, M.2    Bouwmeester, H.J.3    Posthumus, M.A.4    Brodelius, P.E.5
  • 181
    • 0029087870 scopus 로고
    • Purification and characterization of taxa-4(5), 11(12)-diene synthase from Pacific yew (Taxus brevifolia) that catalyzes the first committed step of taxol biosynthesis
    • Hezari, M.; Lewis, N.G.; Croteau, R. Purification and characterization of taxa-4(5), 11(12)-diene synthase from Pacific yew (Taxus brevifolia) that catalyzes the first committed step of taxol biosynthesis. Arch. Biochem. Biophys., 1995, 322, 437-444.
    • (1995) Arch. Biochem. Biophys. , vol.322 , pp. 437-444
    • Hezari, M.1    Lewis, N.G.2    Croteau, R.3
  • 182
    • 79953729355 scopus 로고    scopus 로고
    • Plastid biotechnology: Food, fuel, and medicine for the 21st century
    • Maliga, P.; Bock, R. Plastid biotechnology: food, fuel, and medicine for the 21st century. Plant Physiol., 2011, 155, 1501-1510.
    • (2011) Plant Physiol. , vol.155 , pp. 1501-1510
    • Maliga, P.1    Bock, R.2
  • 183
    • 33846050084 scopus 로고    scopus 로고
    • Contained metabolic engineering in tomatoes by expression of carotenoid biosynthesis genes from the plastid genome
    • Wurbs, D.; Ruf, S.; Bock, R. Contained metabolic engineering in tomatoes by expression of carotenoid biosynthesis genes from the plastid genome. Plant J., 2007, 49, 276-288.
    • (2007) Plant J. , vol.49 , pp. 276-288
    • Wurbs, D.1    Ruf, S.2    Bock, R.3
  • 185
    • 70349196806 scopus 로고    scopus 로고
    • Enhancement of carotenoid biosynthesis in transplastomic tomatoes by induced lycopene-to-provitamin A conversion
    • Apel, W.; Bock, R. Enhancement of carotenoid biosynthesis in transplastomic tomatoes by induced lycopene-to-provitamin A conversion. Plant Physiol., 2009, 151, 59-66.
    • (2009) Plant Physiol. , vol.151 , pp. 59-66
    • Apel, W.1    Bock, R.2
  • 186
    • 1542368230 scopus 로고    scopus 로고
    • Plastid transformation in higher plants
    • Maliga, P. Plastid transformation in higher plants. Annu. Rev. Plant Biol., 2004, 55, 289-313.
    • (2004) Annu. Rev. Plant Biol. , vol.55 , pp. 289-313
    • Maliga, P.1
  • 187
    • 34147158443 scopus 로고    scopus 로고
    • Plastid biotechnology: Prospects for herbicide and insect resistance, metabolic engineering and molecular farming
    • Bock, R. Plastid biotechnology: prospects for herbicide and insect resistance, metabolic engineering and molecular farming. Curr. Opin. Biotechnol., 2007, 18, 100-106.
    • (2007) Curr. Opin. Biotechnol. , vol.18 , pp. 100-106
    • Bock, R.1


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