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Volumn 6, Issue , 2012, Pages 371-384

Update on taxane development: New analogs and new formulations

Author keywords

New antimicrotubule agents; New taxane formulations; Novel taxanes; Taxane analogs; Taxane(s)

Indexed keywords

7 METHYLTHIOMETHYLPACLITAXEL; ALBUMIN; ANTIEMETIC AGENT; BEVACIZUMAB; CABAZITAXEL; CARBOPLATIN; CISPLATIN; CORTICOSTEROID; CREMOPHOR; DOCETAXEL; DOXORUBICIN; EPOTHILONE DERIVATIVE; ERIBULIN; GAMMA GLUTAMYLTRANSFERASE; GEMCITABINE; GLUTAMIC ACID; IXABEPILONE; LAROTAXEL; LIPOSOME; MITOXANTRONE; NANOPARTICLE; PACLITAXEL; PACLITAXEL POLIGLUMEX; POLYMER; SOLVENT; TAXANE DERIVATIVE; TAXOID; TESETAXEL; UNINDEXED DRUG; VINFLUNINE;

EID: 84872288933     PISSN: 11778881     EISSN: None     Source Type: Journal    
DOI: 10.2147/DDDT.S28997     Document Type: Review
Times cited : (252)

References (75)
  • 1
    • 0015211527 scopus 로고
    • Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
    • Wani MC, Taylor HL, Wall ME, Coggon P, McPhail AT. Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc. 1971;93:2325-2327.
    • (1971) J Am Chem Soc , vol.93 , pp. 2325-2327
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3    Coggon, P.4    McPhail, A.T.5
  • 2
    • 0034880214 scopus 로고    scopus 로고
    • Cremophor EL: The drawbacks and advantages of vehicle selection for drug formulation
    • Gelderblom H, Verweij J, Nooter K, Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer. 2001;37:1590-1598.
    • (2001) Eur J Cancer , vol.37 , pp. 1590-1598
    • Gelderblom, H.1    Verweij, J.2    Nooter, K.3    Sparreboom, A.4
  • 3
    • 0041703019 scopus 로고    scopus 로고
    • Pharmacological effects of formulation vehicles: Implications for cancer chemotherapy
    • ten Tije AJ, Verweij J, Loos WJ, Sparreboom A. Pharmacological effects of formulation vehicles: implications for cancer chemotherapy. Clin Pharmacokinet. 2003;42:665-685.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 665-685
    • ten Tije, A.J.1    Verweij, J.2    Loos, W.J.3    Sparreboom, A.4
  • 4
    • 0036096946 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel
    • Ibrahim NK, Desai N, Legha S, et al. Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. Clin Cancer Res. 2002;8: 1038-1044.
    • (2002) Clin Cancer Res , vol.8 , pp. 1038-1044
    • Ibrahim, N.K.1    Desai, N.2    Legha, S.3
  • 5
    • 84872282063 scopus 로고    scopus 로고
    • Evidence of greater antitumor activity of cremophor-free nanoparticle albumin-bound (nab) paclitaxel (Abraxane) compared to Taxol: Role of novel albumin transporter mechanism
    • Desai N, Trieu V, Yao R. Evidence of greater antitumor activity of cremophor-free nanoparticle albumin-bound (nab) paclitaxel (Abraxane) compared to Taxol: role of novel albumin transporter mechanism. Breast Cancer Res Treat. 2003;8:1038-1044.
    • (2003) Breast Cancer Res Treat , vol.8 , pp. 1038-1044
    • Desai, N.1    Trieu, V.2    Yao, R.3
  • 6
    • 32944482677 scopus 로고    scopus 로고
    • Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
    • Gradishar WJ, Tjulandin S, Davidson N, et al. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol. 2005;23:7794-7803.
    • (2005) J Clin Oncol , vol.23 , pp. 7794-7803
    • Gradishar, W.J.1    Tjulandin, S.2    Davidson, N.3
  • 7
    • 68949114599 scopus 로고    scopus 로고
    • Signifcantly longer progression-free survival with nab-paclitaxel compared with docetaxel as first-line therapy for metastatic breast cancer
    • Gradishar WJ, Krasnojon D, Cheporov S, et al. Signifcantly longer progression-free survival with nab-paclitaxel compared with docetaxel as first-line therapy for metastatic breast cancer. J Clin Oncol. 2009;27:3611-3619.
    • (2009) J Clin Oncol , vol.27 , pp. 3611-3619
    • Gradishar, W.J.1    Krasnojon, D.2    Cheporov, S.3
  • 8
    • 84867573551 scopus 로고    scopus 로고
    • CALGB 40502/NCCTG N063H: Randomized phase III trial of weekly paclitaxel (P) compared to weekly nanoparticle albumin bound nab-paclitaxel (NP) or ixabepilone (Ix) with or without bevacizumab (B) as first-line therapy for locally recurrent or metastatic breast cancer (MBC)
    • CRA1002
    • Rugo HS, Barry WT, Moreno-Aspitia A, et al. CALGB 40502/NCCTG N063H: Randomized phase III trial of weekly paclitaxel (P) compared to weekly nanoparticle albumin bound nab-paclitaxel (NP) or ixabepilone (Ix) with or without bevacizumab (B) as first-line therapy for locally recurrent or metastatic breast cancer (MBC). ASCO Meeting Abstracts. 2012;30:CRA1002.
    • (2012) ASCO Meeting Abstracts , vol.30
    • Rugo, H.S.1    Barry, W.T.2    Moreno-Aspitia, A.3
  • 9
    • 59449102526 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors
    • Mita AC, Denis LJ, Rowinsky EK, et al. Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors. Clin Cancer Res. 2009;15:723-730.
    • (2009) Clin Cancer Res , vol.15 , pp. 723-730
    • Mita, A.C.1    Denis, L.J.2    Rowinsky, E.K.3
  • 10
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
    • de Bono JS, Oudard S, Ozguroglu M, et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010;376:1147-1154.
    • (2010) Lancet , vol.376 , pp. 1147-1154
    • de Bono, J.S.1    Oudard, S.2    Ozguroglu, M.3
  • 11
    • 79952638007 scopus 로고    scopus 로고
    • Critical appraisal of cabazitaxel in the management of advanced prostate cancer
    • Pal SK, Twardowski P, Sartor O. Critical appraisal of cabazitaxel in the management of advanced prostate cancer. Clin Interv Aging. 2010;5:395-402.
    • (2010) Clin Interv Aging , vol.5 , pp. 395-402
    • Pal, S.K.1    Twardowski, P.2    Sartor, O.3
  • 12
    • 0038419962 scopus 로고    scopus 로고
    • DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo
    • Shionoya M, Jimbo T, Kitagawa M, Soga T, Tohgo A. DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo. Cancer Sci. 2003;94:459-466.
    • (2003) Cancer Sci , vol.94 , pp. 459-466
    • Shionoya, M.1    Jimbo, T.2    Kitagawa, M.3    Soga, T.4    Tohgo, A.5
  • 13
    • 50349093533 scopus 로고    scopus 로고
    • Phase I/II study of a 3 weekly oral taxane (DJ-927) in patients with recurrent, advanced non-small cell lung cancer
    • Baas P, Szczesna A, Albert I, et al. Phase I/II study of a 3 weekly oral taxane (DJ-927) in patients with recurrent, advanced non-small cell lung cancer. J Thorac Oncol. 2008;3:745-750.
    • (2008) J Thorac Oncol , vol.3 , pp. 745-750
    • Baas, P.1    Szczesna, A.2    Albert, I.3
  • 14
    • 82455162574 scopus 로고    scopus 로고
    • Tesetaxel, a new oral taxane, in combination with capecitabine: A phase I, dose-escalation study in patients with advanced solid tumors
    • Saif M W, Sarantopoulos J, Patnaik A, Tolcher AW, Takimoto C, Beeram M. Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I, dose-escalation study in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011;68: 1565-1573.
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 1565-1573
    • Saif, M.W.1    Sarantopoulos, J.2    Patnaik, A.3    Tolcher, A.W.4    Takimoto, C.5    Beeram, M.6
  • 15
    • 0037619168 scopus 로고    scopus 로고
    • Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: Characterization, preclinical pharmacology, and preliminary clinical data
    • Singer JW, Baker B, De Vries P, et al. Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data. Adv Exp Med Biol. 2003;519:81-99.
    • (2003) Adv Exp Med Biol , vol.519 , pp. 81-99
    • Singer, J.W.1    Baker, B.2    de Vries, P.3
  • 16
    • 0032101105 scopus 로고    scopus 로고
    • Complete regression of well-established tumors using a novel water-soluble poly(L-glutamic acid)-paclitaxel conjugate
    • Li C, Yu DF, Newman RA, et al. Complete regression of well-established tumors using a novel water-soluble poly(L-glutamic acid)-paclitaxel conjugate. Cancer Res. 1998;58:2404-2409.
    • (1998) Cancer Res , vol.58 , pp. 2404-2409
    • Li, C.1    Yu, D.F.2    Newman, R.A.3
  • 17
    • 0032962184 scopus 로고    scopus 로고
    • Antitumor activity of poly(L-glutamic acid)-paclitaxel on syngeneic and xenografted tumors
    • Li C, Price JE, Milas L, et al. Antitumor activity of poly(L-glutamic acid)-paclitaxel on syngeneic and xenografted tumors. Clin Cancer Res. 1999;5:891-897.
    • (1999) Clin Cancer Res , vol.5 , pp. 891-897
    • Li, C.1    Price, J.E.2    Milas, L.3
  • 18
    • 67349223892 scopus 로고    scopus 로고
    • Phase I study of paclitaxel poliglumex administered weekly for patients with advanced solid malignancies
    • Mita M, Mita A, Sarantopoulos J, et al. Phase I study of paclitaxel poliglumex administered weekly for patients with advanced solid malignancies. Cancer Chemother Pharmacol. 2009;64:287-295.
    • (2009) Cancer Chemother Pharmacol , vol.64 , pp. 287-295
    • Mita, M.1    Mita, A.2    Sarantopoulos, J.3
  • 19
    • 50349101826 scopus 로고    scopus 로고
    • Randomized phase III trial comparing single-agent paclitaxel Poliglumex (CT-2103, PPX) with single-agent gemcitabine or vinorelbine for the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer
    • O'Brien ME, Socinski MA, Popovich AY, et al. Randomized phase III trial comparing single-agent paclitaxel Poliglumex (CT-2103, PPX) with single-agent gemcitabine or vinorelbine for the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer. J Thorac Oncol. 2008;3:728-734.
    • (2008) J Thorac Oncol , vol.3 , pp. 728-734
    • O'Brien, M.E.1    Socinski, M.A.2    Popovich, A.Y.3
  • 20
    • 44649193032 scopus 로고    scopus 로고
    • Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer
    • Langer CJ, O'Byrne KJ, Socinski MA, et al. Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer. J Thorac Oncol. 2008;3:623-630.
    • (2008) J Thorac Oncol , vol.3 , pp. 623-630
    • Langer, C.J.1    O'Byrne, K.J.2    Socinski, M.A.3
  • 21
    • 43649092756 scopus 로고    scopus 로고
    • Phase III trial comparing paclitaxel poliglumex vs docetaxel in the second-line treatment of non-small-cell lung cancer
    • Paz-Ares L, Ross H, O'Brien M, et al. Phase III trial comparing paclitaxel poliglumex vs docetaxel in the second-line treatment of non-small-cell lung cancer. Br J Cancer. 2008;98:1608-1613.
    • (2008) Br J Cancer , vol.98 , pp. 1608-1613
    • Paz-Ares, L.1    Ross, H.2    O'Brien, M.3
  • 22
    • 56749178680 scopus 로고    scopus 로고
    • A phase II trial of paclitaxel poliglumex in recurrent or persistent ovarian or primary peritoneal cancer (EOC): A Gynecologic Oncology Group Study
    • Gynecologic Oncology Group Study
    • Sabbatini P, Sill M W, O'Malley D, Adler L, Secord AA, Gynecologic Oncology Group Study. A phase II trial of paclitaxel poliglumex in recurrent or persistent ovarian or primary peritoneal cancer (EOC): a Gynecologic Oncology Group Study. Gynecol Oncol. 2008;111:455-460.
    • (2008) Gynecol Oncol , vol.111 , pp. 455-460
    • Sabbatini, P.1    Sill, M.W.2    O'Malley, D.3    Adler, L.4    Secord, A.A.5
  • 24
    • 84872293493 scopus 로고    scopus 로고
    • A phase II study of paclitaxel poliglumex (PPX), temozolamide (TMZ), and radiation (RT) for newly diagnosed high-grade gliomas
    • Jeyapalan SA, Goldmann M, Donahue J, et al. A phase II study of paclitaxel poliglumex (PPX), temozolamide (TMZ), and radiation (RT) for newly diagnosed high-grade gliomas. ASCO Meeting Abstracts. 2011;29:2036.
    • (2036) ASCO Meeting Abstracts , vol.2011 , pp. 29
    • Jeyapalan, S.A.1    Goldmann, M.2    Donahue, J.3
  • 26
    • 84856236634 scopus 로고    scopus 로고
    • Neoadjuvant paclitaxel poliglumex, cisplatin, and radiation for esophageal cancer: A phase 2 trial
    • Dipetrillo T, Suntharalingam M, Ng T, et al. Neoadjuvant paclitaxel poliglumex, cisplatin, and radiation for esophageal cancer: a phase 2 trial. Am J Clin Oncol. 2012;35:64-67.
    • (2012) Am J Clin Oncol , vol.35 , pp. 64-67
    • Dipetrillo, T.1    Suntharalingam, M.2    Ng, T.3
  • 27
    • 34250612643 scopus 로고    scopus 로고
    • Phase II study of CT-2103 as firstor second-line chemotherapy in patients with metastatic breast cancer: Unexpected incidence of hypersensitivity reactions
    • Lin NU, Parker LM, Come SE, et al. Phase II study of CT-2103 as firstor second-line chemotherapy in patients with metastatic breast cancer: unexpected incidence of hypersensitivity reactions. Invest New Drugs. 2007;25:369-375.
    • (2007) Invest New Drugs , vol.25 , pp. 369-375
    • Lin, N.U.1    Parker, L.M.2    Come, S.E.3
  • 28
    • 0000172793 scopus 로고    scopus 로고
    • Cationic liposomes target angiogenic endothelial cells in tumors and chronic infammation in mice
    • Thurston G, McLean J W, Rizen M, et al. Cationic liposomes target angiogenic endothelial cells in tumors and chronic infammation in mice. J Clin Invest. 1998;101:1401-1413.
    • (1998) J Clin Invest , vol.101 , pp. 1401-1413
    • Thurston, G.1    McLean, J.W.2    Rizen, M.3
  • 29
    • 1942484476 scopus 로고    scopus 로고
    • Neovascular targeting chemotherapy: Encapsulation of paclitaxel in cationic liposomes impairs functional tumor microvasculature
    • Strieth S, Eichhorn ME, Sauer B, et al. Neovascular targeting chemotherapy: encapsulation of paclitaxel in cationic liposomes impairs functional tumor microvasculature. Int J Cancer. 2004;110:117-124.
    • (2004) Int J Cancer , vol.110 , pp. 117-124
    • Strieth, S.1    Eichhorn, M.E.2    Sauer, B.3
  • 30
    • 36849081545 scopus 로고    scopus 로고
    • Tumor-selective vessel occlusions by platelets after vascular targeting chemotherapy using paclitaxel encapsulated in cationic liposomes
    • Strieth S, Nussbaum C F, Eichhorn ME, et al. Tumor-selective vessel occlusions by platelets after vascular targeting chemotherapy using paclitaxel encapsulated in cationic liposomes. Int J Cancer. 2008;122:452-460.
    • (2008) Int J Cancer , vol.122 , pp. 452-460
    • Strieth, S.1    Nussbaum, C.F.2    Eichhorn, M.E.3
  • 31
    • 51649088789 scopus 로고    scopus 로고
    • Paclitaxel encapsulated in cationic liposomes increases tumor microvessel leakiness and improves therapeutic effcacy in combination with Cisplatin
    • Strieth S, Eichhorn ME, Werner A, et al. Paclitaxel encapsulated in cationic liposomes increases tumor microvessel leakiness and improves therapeutic effcacy in combination with Cisplatin. Clin Cancer Res. 2008;14:4603-4611.
    • (2008) Clin Cancer Res , vol.14 , pp. 4603-4611
    • Strieth, S.1    Eichhorn, M.E.2    Werner, A.3
  • 32
    • 22844439645 scopus 로고    scopus 로고
    • Recent advances in the new generation taxane anticancer agents
    • Geney R, Chen J, Ojima I. Recent advances in the new generation taxane anticancer agents. Med Chem. 2005;1:125-139.
    • (2005) Med Chem , vol.1 , pp. 125-139
    • Geney, R.1    Chen, J.2    Ojima, I.3
  • 33
    • 68349121331 scopus 로고    scopus 로고
    • Paclitaxel encapsulated in cationic liposomes: A new option for neovascular targeting for the treatment of prostate cancer
    • Bode C, Trojan L, Weiss C, et al. Paclitaxel encapsulated in cationic liposomes: a new option for neovascular targeting for the treatment of prostate cancer. Oncol Rep. 2009;22:321-326.
    • (2009) Oncol Rep , vol.22 , pp. 321-326
    • Bode, C.1    Trojan, L.2    Weiss, C.3
  • 34
    • 74049087050 scopus 로고    scopus 로고
    • Vascular targeting by EndoTAG-1 enhances therapeutic effcacy of conventional chemotherapy in lung and pancreatic cancer
    • Eichhorn ME, Ischenko I, Luedemann S, et al. Vascular targeting by EndoTAG-1 enhances therapeutic effcacy of conventional chemotherapy in lung and pancreatic cancer. Int J Cancer. 2010;126:1235-1245.
    • (2010) Int J Cancer , vol.126 , pp. 1235-1245
    • Eichhorn, M.E.1    Ischenko, I.2    Luedemann, S.3
  • 35
    • 84860463458 scopus 로고    scopus 로고
    • Cationic liposomal paclitaxel plus gemcitabine or gemcitabine alone in patients with advanced pancreatic cancer: A randomized controlled phase II trial
    • Löhr JM, Haas SL, Bechstein WO, et al. Cationic liposomal paclitaxel plus gemcitabine or gemcitabine alone in patients with advanced pancreatic cancer: a randomized controlled phase II trial. Ann Oncol. 2012;23:1214-1222.
    • (2012) Ann Oncol , vol.23 , pp. 1214-1222
    • Löhr, J.M.1    Haas, S.L.2    Bechstein, W.O.3
  • 36
    • 78650477511 scopus 로고    scopus 로고
    • Results of the first randomized phase II study of cationic liposomal paclitaxel (EndoTAG-1) targeting tumor endothelial cells in advanced triple-negative breast cancer (TNBC)
    • Abstr LBA12
    • Awada A, Bondarenko I, Tarasova O, et al. Results of the first randomized phase II study of cationic liposomal paclitaxel (EndoTAG-1) targeting tumor endothelial cells in advanced triple-negative breast cancer (TNBC). Ann. Oncol. 2010;21(8); 85 (Abstr LBA12).
    • (2010) Ann. Oncol , vol.21 , Issue.8 , pp. 85
    • Awada, A.1    Bondarenko, I.2    Tarasova, O.3
  • 37
  • 38
    • 0034857136 scopus 로고    scopus 로고
    • Preclinical evaluation of new taxoids
    • Bissery MC. Preclinical evaluation of new taxoids. Curr Pharm Des. 2001;7:1251-1257.
    • (2001) Curr Pharm Des , vol.7 , pp. 1251-1257
    • Bissery, M.C.1
  • 39
    • 58149140537 scopus 로고    scopus 로고
    • Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIIB or stage IV non-small cell lung cancer
    • Zatloukal P, Gervais R, Vansteenkiste J, et al. Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIIB or stage IV non-small cell lung cancer. J Thorac Oncol. 2008;3:894-901.
    • (2008) J Thorac Oncol , vol.3 , pp. 894-901
    • Zatloukal, P.1    Gervais, R.2    Vansteenkiste, J.3
  • 40
    • 46249085475 scopus 로고    scopus 로고
    • Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy
    • Dieras V, Limentani S, Romieu G, et al. Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy. Ann Oncol. 2008;19:1255-1260.
    • (2008) Ann Oncol , vol.19 , pp. 1255-1260
    • Dieras, V.1    Limentani, S.2    Romieu, G.3
  • 41
    • 0035858296 scopus 로고    scopus 로고
    • In vivo evaluation of polymeric micellar paclitaxel formulation: Toxicity and effcacy
    • Kim SC, Kim DW, Shim YH, et al. In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and effcacy. J Control Release. 2001;72:191-202.
    • (2001) J Control Release , vol.72 , pp. 191-202
    • Kim, S.C.1    Kim, D.W.2    Shim, Y.H.3
  • 42
    • 0030827821 scopus 로고    scopus 로고
    • Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel
    • Zhang X, Burt HM, Mangold G, et al. Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel. Anticancer Drugs. 1997;8:696-701.
    • (1997) Anticancer Drugs , vol.8 , pp. 696-701
    • Zhang, X.1    Burt, H.M.2    Mangold, G.3
  • 43
    • 0030965632 scopus 로고    scopus 로고
    • An investigation of the antitumour activity and biodistribution of polymeric micellar paclitaxel
    • Zhang X, Burt HM, Von Hoff D, et al. An investigation of the antitumour activity and biodistribution of polymeric micellar paclitaxel. Cancer Chemother Pharmacol. 1997;40:81-86.
    • (1997) Cancer Chemother Pharmacol , vol.40 , pp. 81-86
    • Zhang, X.1    Burt, H.M.2    von Hoff, D.3
  • 44
    • 37349080672 scopus 로고    scopus 로고
    • Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer
    • Kim DW, Kim SY, Kim HK, et al. Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer. Ann Oncol. 2007;18:2009-2014.
    • (2007) Ann Oncol , vol.18 , pp. 2009-2014
    • Kim, D.W.1    Kim, S.Y.2    Kim, H.K.3
  • 45
    • 39749178252 scopus 로고    scopus 로고
    • Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer
    • Lee KS, Chung HC, Im SA, et al. Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer. Breast Cancer Res Treat. 2008;108:241-250.
    • (2008) Breast Cancer Res Treat , vol.108 , pp. 241-250
    • Lee, K.S.1    Chung, H.C.2    Im, S.A.3
  • 46
    • 16544373481 scopus 로고    scopus 로고
    • A multi-center, late phase II clinical trial of Genexol (paclitaxel) and cisplatin for patients with advanced gastric cancer
    • Park SR, Oh DY, Kim DW, et al. A multi-center, late phase II clinical trial of Genexol (paclitaxel) and cisplatin for patients with advanced gastric cancer. Oncol Rep. 2004;12:1059-1064.
    • (2004) Oncol Rep , vol.12 , pp. 1059-1064
    • Park, S.R.1    Oh, D.Y.2    Kim, D.W.3
  • 47
  • 48
    • 0034787765 scopus 로고    scopus 로고
    • Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel
    • Bradley MO, Webb NL, Anthony FH, et al. Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel. Clin Cancer Res. 2001;7:3229-3238.
    • (2001) Clin Cancer Res , vol.7 , pp. 3229-3238
    • Bradley, M.O.1    Webb, N.L.2    Anthony, F.H.3
  • 49
    • 12244263487 scopus 로고    scopus 로고
    • Disposition of docosahexaenoic acid-paclitaxel, a novel taxane, in blood: In vitro and clinical pharmacokinetic studies
    • Sparreboom A, Wolff AC, Verweij J, et al. Disposition of docosahexaenoic acid-paclitaxel, a novel taxane, in blood: in vitro and clinical pharmacokinetic studies. Clin Cancer Res. 2003;9:151-159.
    • (2003) Clin Cancer Res , vol.9 , pp. 151-159
    • Sparreboom, A.1    Wolff, A.C.2    Verweij, J.3
  • 50
    • 58249142582 scopus 로고    scopus 로고
    • Phase 1 and pharmacokinetic study of weekly docosahexaenoic acid-paclitaxel, Taxoprexin, in resistant solid tumor malignancies
    • Fracasso PM, Picus J, Wildi JD, et al. Phase 1 and pharmacokinetic study of weekly docosahexaenoic acid-paclitaxel, Taxoprexin, in resistant solid tumor malignancies. Cancer Chemother Pharmacol. 2009;63:451-458.
    • (2009) Cancer Chemother Pharmacol , vol.63 , pp. 451-458
    • Fracasso, P.M.1    Picus, J.2    Wildi, J.D.3
  • 51
    • 68949136812 scopus 로고    scopus 로고
    • Phase 2 open-label study of weekly docosahexaenoic acid-paclitaxel in cutaneous and mucosal metastatic melanoma patients
    • Homsi J, Bedikian AY, Kim KB, et al. Phase 2 open-label study of weekly docosahexaenoic acid-paclitaxel in cutaneous and mucosal metastatic melanoma patients. Melanoma Res. 2009;19:238-242.
    • (2009) Melanoma Res , vol.19 , pp. 238-242
    • Homsi, J.1    Bedikian, A.Y.2    Kim, K.B.3
  • 52
    • 79953324540 scopus 로고    scopus 로고
    • Phase 3 study of docosahexaenoic acid-paclitaxel versus dacarbazine in patients with metastatic malignant melanoma
    • Bedikian AY, DeConti RC, Conry R, et al. Phase 3 study of docosahexaenoic acid-paclitaxel versus dacarbazine in patients with metastatic malignant melanoma. Ann Oncol. 2011;22:787-793.
    • (2011) Ann Oncol , vol.22 , pp. 787-793
    • Bedikian, A.Y.1    Deconti, R.C.2    Conry, R.3
  • 53
    • 37249036585 scopus 로고    scopus 로고
    • A phase II open-label study of DHA-paclitaxel (Taxoprexin) by 2-h intravenous infusion in previously untreated patients with locally advanced or metastatic gastric or oesophageal adenocarcinoma
    • Jones RJ, Hawkins RE, Eatock MM, et al. A phase II open-label study of DHA-paclitaxel (Taxoprexin) by 2-h intravenous infusion in previously untreated patients with locally advanced or metastatic gastric or oesophageal adenocarcinoma. Cancer Chemother Pharmacol. 2008;61:435-441.
    • (2008) Cancer Chemother Pharmacol , vol.61 , pp. 435-441
    • Jones, R.J.1    Hawkins, R.E.2    Eatock, M.M.3
  • 54
    • 0035340984 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of BMS-184476, a taxane with greater potency and solubility than paclitaxel
    • Hidalgo M, Aylesworth C, Hammond LA, et al. Phase I and pharmacokinetic study of BMS-184476, a taxane with greater potency and solubility than paclitaxel. J Clin Oncol. 2001;19:2493-2503.
    • (2001) J Clin Oncol , vol.19 , pp. 2493-2503
    • Hidalgo, M.1    Aylesworth, C.2    Hammond, L.A.3
  • 55
    • 0035479085 scopus 로고    scopus 로고
    • The novel taxane analogs, BMS-184476 and BMS-188797, potentiate the effects of radiation therapy in vitro and in vivo against human lung cancer cells
    • Kim JS, Amorino G P, Pyo H, Cao Q, Price JO, Choy H. The novel taxane analogs, BMS-184476 and BMS-188797, potentiate the effects of radiation therapy in vitro and in vivo against human lung cancer cells. Int J Radiat Oncol Biol Phys. 2001;51:525-534.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 525-534
    • Kim, J.S.1    Amorino, G.P.2    Pyo, H.3    Cao, Q.4    Price, J.O.5    Choy, H.6
  • 56
    • 3843068912 scopus 로고    scopus 로고
    • Phase I trial of the novel taxane BMS-184476 administered in combination with carboplatin every 21 days
    • Bilenker JH, Stevenson J P, Gallagher ML, Vaughn D, Cohen MB, O'Dwyer PJ. Phase I trial of the novel taxane BMS-184476 administered in combination with carboplatin every 21 days. Br J Cancer. 2004;91:213-218.
    • (2004) Br J Cancer , vol.91 , pp. 213-218
    • Bilenker, J.H.1    Stevenson, J.P.2    Gallagher, M.L.3    Vaughn, D.4    Cohen, M.B.5    O'Dwyer, P.J.6
  • 57
    • 0036719791 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of the new taxane analog BMS-184476 given weekly in patients with advanced malignancies
    • Plummer R, Ghielmini M, Calvert P, et al. Phase I and pharmacokinetic study of the new taxane analog BMS-184476 given weekly in patients with advanced malignancies. Clin Cancer Res. 2002;8:2788-2797.
    • (2002) Clin Cancer Res , vol.8 , pp. 2788-2797
    • Plummer, R.1    Ghielmini, M.2    Calvert, P.3
  • 58
    • 20944441476 scopus 로고    scopus 로고
    • Phase II trial of the novel taxane BMS-184476 as second-line in non-small-cell lung cancer
    • Camps C, Felip E, Sanchez JM, et al. Phase II trial of the novel taxane BMS-184476 as second-line in non-small-cell lung cancer. Ann Oncol. 2005;16:597-601.
    • (2005) Ann Oncol , vol.16 , pp. 597-601
    • Camps, C.1    Felip, E.2    Sanchez, J.M.3
  • 59
    • 10744229319 scopus 로고    scopus 로고
    • Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin
    • Sessa C, Perotti A, Salvatorelli E, et al. Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin. Eur J Cancer. 2004;40:563-570.
    • (2004) Eur J Cancer , vol.40 , pp. 563-570
    • Sessa, C.1    Perotti, A.2    Salvatorelli, E.3
  • 60
    • 79953713649 scopus 로고    scopus 로고
    • A multicentre doseescalating study of cabazitaxel (XRP6258) in combination with capecitabine in patients with metastatic breast cancer progressing after anthracycline and taxane treatment: A phase I/II study
    • Villanueva C, Awada A, Campone M, et al. A multicentre doseescalating study of cabazitaxel (XRP6258) in combination with capecitabine in patients with metastatic breast cancer progressing after anthracycline and taxane treatment: a phase I/II study. Eur J Cancer. 2011;47:1037-1045.
    • (2011) Eur J Cancer , vol.47 , pp. 1037-1045
    • Villanueva, C.1    Awada, A.2    Campone, M.3
  • 61
    • 33747887418 scopus 로고    scopus 로고
    • Abraxane, a novel Cremophor-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer
    • Green MR, Manikhas GM, Orlov S, et al. Abraxane, a novel Cremophor-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer. Ann Oncol. 2006;17:1263-1268.
    • (2006) Ann Oncol , vol.17 , pp. 1263-1268
    • Green, M.R.1    Manikhas, G.M.2    Orlov, S.3
  • 62
    • 39149105016 scopus 로고    scopus 로고
    • Phase I/II trial of weekly intravenous 130-nm albumin-bound paclitaxel as initial chemotherapy in patients with stage IV non-small-cell lung cancer
    • Rizvi NA, Riely GJ, Azzoli CG, et al. Phase I/II trial of weekly intravenous 130-nm albumin-bound paclitaxel as initial chemotherapy in patients with stage IV non-small-cell lung cancer. J Clin Oncol. 2008;26:639-643.
    • (2008) J Clin Oncol , vol.26 , pp. 639-643
    • Rizvi, N.A.1    Riely, G.J.2    Azzoli, C.G.3
  • 63
    • 83355169753 scopus 로고    scopus 로고
    • Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: A phase I/II Trial
    • von Hoff DD, Ramanathan RK, Borad MJ, et al. Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II Trial. J Clin Oncol. 2011;29:4548-4554.
    • (2011) J Clin Oncol , vol.29 , pp. 4548-4554
    • von Hoff, D.D.1    Ramanathan, R.K.2    Borad, M.J.3
  • 64
    • 84876140632 scopus 로고    scopus 로고
    • A Phase II trial of nab-paclitaxel as second-line therapy in patients with advanced pancreatic cancer
    • Epub February
    • Hosein PJ, de Lima Lopes G, Jr, Pastorini VH, et al. A Phase II trial of nab-paclitaxel as second-line therapy in patients with advanced pancreatic cancer. Am J Clin Oncol. Epub February 2, 2012.
    • (2012) Am J Clin Oncol , pp. 2
    • Hosein, P.J.1    de Lima Lopes Jr., G.2    Pastorini, V.H.3
  • 65
    • 79957759352 scopus 로고    scopus 로고
    • A phase II evaluation of nanoparticle, albumin-bound (nab) paclitaxel in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer: A Gynecologic Oncology Group study
    • Coleman RL, Brady WE, McMeekin DS, et al. A phase II evaluation of nanoparticle, albumin-bound (nab) paclitaxel in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer: a Gynecologic Oncology Group study. Gynecol Oncol. 2011;122:111-115.
    • (2011) Gynecol Oncol , vol.122 , pp. 111-115
    • Coleman, R.L.1    Brady, W.E.2    McMeekin, D.S.3
  • 66
    • 84872345038 scopus 로고    scopus 로고
    • Tesetaxel, a novel oral taxane, as second-line therapy for advanced gastroesophageal cancer: Activity in a dose-ranging study
    • Ajani JA, Sun W, Rha SY, Baker JS, Mulcahy MF. Tesetaxel, a novel oral taxane, as second-line therapy for advanced gastroesophageal cancer: Activity in a dose-ranging study. ASCO Meeting Abstracts. 2012;30:47.
    • (2012) ASCO Meeting Abstracts , vol.30 , pp. 47
    • Ajani, J.A.1    Sun, W.2    Rha, S.Y.3    Baker, J.S.4    Mulcahy, M.F.5
  • 67
    • 33845628267 scopus 로고    scopus 로고
    • Phase II trial of DJ-927, an oral tubulin depolymerization inhibitor, in the treatment of metastatic colorectal cancer
    • Moore MR, Jones C, Harker G, et al. Phase II trial of DJ-927, an oral tubulin depolymerization inhibitor, in the treatment of metastatic colorectal cancer. ASCO Meeting Abstracts. 2006;24:3591.
    • (2006) ASCO Meeting Abstracts , vol.24 , pp. 3591
    • Moore, M.R.1    Jones, C.2    Harker, G.3
  • 68
    • 84857441780 scopus 로고    scopus 로고
    • Phase II clinical trial of Genexol(R) (paclitaxel) and carboplatin for patients with advanced non-small cell lung cancer
    • Kim HJ, Kim KH, Yun J, et al. Phase II clinical trial of Genexol(R) (paclitaxel) and carboplatin for patients with advanced non-small cell lung cancer. Cancer Res Treat. 2011;43:19-23.
    • (2011) Cancer Res Treat , vol.43 , pp. 19-23
    • Kim, H.J.1    Kim, K.H.2    Yun, J.3
  • 69
    • 34247880421 scopus 로고    scopus 로고
    • DHA-paclitaxel (Taxoprexin) as first-line treatment in patients with stage IIIB or IV non-small cell lung cancer: Report of a phase II open-label multicenter trial
    • Payne M, Ellis P, Dunlop D, et al. DHA-paclitaxel (Taxoprexin) as first-line treatment in patients with stage IIIB or IV non-small cell lung cancer: report of a phase II open-label multicenter trial. J Thorac Oncol. 2006;1:984-990.
    • (2006) J Thorac Oncol , vol.1 , pp. 984-990
    • Payne, M.1    Ellis, P.2    Dunlop, D.3
  • 70
    • 10744222643 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic trial of the novel taxane BMS-184476 administered as a 1-hour intravenous infusion in combination with cisplatin every 21 days
    • Sun W, Stevenson J P, Gallagher ML, et al. Phase I and pharmacokinetic trial of the novel taxane BMS-184476 administered as a 1-hour intravenous infusion in combination with cisplatin every 21 days. Clin Cancer Res. 2003;9:5221-5227.
    • (2003) Clin Cancer Res , vol.9 , pp. 5221-5227
    • Sun, W.1    Stevenson, J.P.2    Gallagher, M.L.3
  • 71
    • 79952487463 scopus 로고    scopus 로고
    • Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): A phase 3 open-label randomised study
    • Cortes J, O'Shaughnessy J, Loesch D, et al. Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study. Lancet. 2011;377:914-923.
    • (2011) Lancet , vol.377 , pp. 914-923
    • Cortes, J.1    O'Shaughnessy, J.2    Loesch, D.3
  • 72
    • 36849071808 scopus 로고    scopus 로고
    • Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
    • Thomas ES, Gomez HL, Li RK, et al. Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment. J Clin Oncol. 2007;25:5210-5217.
    • (2007) J Clin Oncol , vol.25 , pp. 5210-5217
    • Thomas, E.S.1    Gomez, H.L.2    Li, R.K.3
  • 73
    • 77954752064 scopus 로고    scopus 로고
    • Randomized Phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
    • Sparano JA, Vrdoljak E, Rixe O, et al. Randomized Phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol. 2010;28:3256-3263.
    • (2010) J Clin Oncol , vol.28 , pp. 3256-3263
    • Sparano, J.A.1    Vrdoljak, E.2    Rixe, O.3
  • 74
    • 75149128685 scopus 로고    scopus 로고
    • Phase III trial of vinfunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract
    • Bellmunt J, Théodore C, Demkov T, et al. Phase III trial of vinfunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract. J Clin Oncol. 2009;27:4454-4461.
    • (2009) J Clin Oncol , vol.27 , pp. 4454-4461
    • Bellmunt, J.1    Théodore, C.2    Demkov, T.3
  • 75
    • 77952316743 scopus 로고    scopus 로고
    • Phase III trial comparing vinfunine with docetaxel in second-line advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy
    • Krzakowski M, Ramlau R, Jassem J, et al. Phase III trial comparing vinfunine with docetaxel in second-line advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy. J Clin Oncol. 2010;28:2167-2173.
    • (2010) J Clin Oncol , vol.28 , pp. 2167-2173
    • Krzakowski, M.1    Ramlau, R.2    Jassem, J.3


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