메뉴 건너뛰기




Volumn 34, Issue , 2017, Pages 39-50

Stem cell therapies in age-related neurodegenerative diseases and stroke

Author keywords

Aging; Neurodegenerative diseases; Plasticity; Self renew; Stem cell; Stroke

Indexed keywords

ADIPOSE DERIVED STEM CELL; AGING; ALZHEIMER DISEASE; BASIC RESEARCH; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL LOSS; CELL REGENERATION; CEREBROVASCULAR ACCIDENT; COGNITIVE DEFECT; DEGENERATIVE DISEASE; EMBRYONIC STEM CELL; ENDOTHELIAL PROGENITOR CELL; GRAY MATTER; HEMATOPOIETIC STEM CELL; HUMAN; INDUCED PLURIPOTENT STEM CELL; MOTOR DYSFUNCTION; NERVE CELL; NERVE CELL PLASTICITY; NEURAL STEM CELL; NONHUMAN; NUCLEAR REPROGRAMMING; OXIDATIVE STRESS; PARKINSON DISEASE; PROTEIN MISFOLDING; REVIEW; STEM CELL SELF-RENEWAL; STEM CELL TRANSPLANTATION; STROKE PATIENT; SYNAPSE; UMBILICAL CORD BLOOD CELL; WHITE MATTER; ANIMAL; BRAIN; METABOLISM; NEURODEGENERATIVE DISEASES; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; STROKE;

EID: 85007200900     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2016.11.002     Document Type: Review
Times cited : (49)

References (197)
  • 1
    • 84858225391 scopus 로고    scopus 로고
    • Alzheimer's disease facts and figures
    • Alzheimer's Associationnon, Alzheimer's disease facts and figures. Alzheimers Dement 8 (2012), 131–168.
    • (2012) Alzheimers Dement , vol.8 , pp. 131-168
    • Alzheimer's Associationnon1
  • 2
    • 84925880097 scopus 로고    scopus 로고
    • Alzheimer's disease facts and figures
    • Alzheimer's Associationnon, Alzheimer's disease facts and figures. Alzheimers Dement 11 (2015), 332–384.
    • (2015) Alzheimers Dement , vol.11 , pp. 332-384
    • Alzheimer's Associationnon1
  • 4
    • 84896316400 scopus 로고    scopus 로고
    • Aging, neurogenesis, and caloric restriction in different model organisms
    • Arslan-Ergul, A., Ozdemir, A.T., Adams, M.M., Aging, neurogenesis, and caloric restriction in different model organisms. Aging Dis. 4 (2013), 221–232.
    • (2013) Aging Dis. , vol.4 , pp. 221-232
    • Arslan-Ergul, A.1    Ozdemir, A.T.2    Adams, M.M.3
  • 5
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson, A., Collin, T., Kirik, D., Kokaia, Z., Lindvall, O., Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat. Med. 8 (2002), 963–970.
    • (2002) Nat. Med. , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 9
    • 34247583987 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration
    • Bae, J.S., Han, H.S., Youn, D.H., Carter, J.E., Modo, M., Schuchman, E.H., Jin, H.K., Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration. Stem Cells (Dayton Ohio) 25 (2007), 1307–1316.
    • (2007) Stem Cells (Dayton Ohio) , vol.25 , pp. 1307-1316
    • Bae, J.S.1    Han, H.S.2    Youn, D.H.3    Carter, J.E.4    Modo, M.5    Schuchman, E.H.6    Jin, H.K.7
  • 12
    • 78650517407 scopus 로고    scopus 로고
    • Transplantation of human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and endogenous neurogenesis after cerebral ischemia in rats
    • Bao, X., Wei, J., Feng, M., Lu, S., Li, G., Dou, W., Ma, W., Ma, S., An, Y., Qin, C., Zhao, R.C., Wang, R., Transplantation of human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and endogenous neurogenesis after cerebral ischemia in rats. Brain Res. 1367 (2011), 103–113.
    • (2011) Brain Res. , vol.1367 , pp. 103-113
    • Bao, X.1    Wei, J.2    Feng, M.3    Lu, S.4    Li, G.5    Dou, W.6    Ma, W.7    Ma, S.8    An, Y.9    Qin, C.10    Zhao, R.C.11    Wang, R.12
  • 13
    • 80052908054 scopus 로고    scopus 로고
    • Cell based therapies in Parkinson's disease
    • Behari, M., Singhal, K.K., Cell based therapies in Parkinson's disease. Ann. Neurosci. 18 (2011), 76–83.
    • (2011) Ann. Neurosci. , vol.18 , pp. 76-83
    • Behari, M.1    Singhal, K.K.2
  • 15
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
    • Bell, R.D., Zlokovic, B.V., Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol. 118 (2009), 103–113.
    • (2009) Acta Neuropathol. , vol.118 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 16
    • 34547890677 scopus 로고    scopus 로고
    • Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia
    • Berninger, B., Costa, M.R., Koch, U., Schroeder, T., Sutor, B., Grothe, B., Gotz, M., Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia. J. Neurosci. 27 (2007), 8654–8664.
    • (2007) J. Neurosci. , vol.27 , pp. 8654-8664
    • Berninger, B.1    Costa, M.R.2    Koch, U.3    Schroeder, T.4    Sutor, B.5    Grothe, B.6    Gotz, M.7
  • 18
    • 11144305796 scopus 로고    scopus 로고
    • Autologous haematopoietic-stem-cell transplantation for multiple sclerosis
    • Blanco, Y., Saiz, A., Carreras, E., Graus, F., Autologous haematopoietic-stem-cell transplantation for multiple sclerosis. Lancet Neurol. 4 (2005), 54–63.
    • (2005) Lancet Neurol. , vol.4 , pp. 54-63
    • Blanco, Y.1    Saiz, A.2    Carreras, E.3    Graus, F.4
  • 19
    • 72749121996 scopus 로고    scopus 로고
    • Optimizing the success of cell transplantation therapy for stroke
    • Bliss, T.M., Andres, R.H., Steinberg, G.K., Optimizing the success of cell transplantation therapy for stroke. Neurobiol. Dis. 37 (2010), 275–283.
    • (2010) Neurobiol. Dis. , vol.37 , pp. 275-283
    • Bliss, T.M.1    Andres, R.H.2    Steinberg, G.K.3
  • 22
    • 84950138219 scopus 로고    scopus 로고
    • Adult mammalian neural stem cells and neurogenesis: five decades later
    • Bond, A.M., Ming, G.L., Song, H., Adult mammalian neural stem cells and neurogenesis: five decades later. Cell Stem Cell 17 (2015), 385–395.
    • (2015) Cell Stem Cell , vol.17 , pp. 385-395
    • Bond, A.M.1    Ming, G.L.2    Song, H.3
  • 23
    • 84877577935 scopus 로고    scopus 로고
    • Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT)
    • Bourin, P., Bunnell, B.A., Casteilla, L., Dominici, M., Katz, A.J., March, K.L., Redl, H., Rubin, J.P., Yoshimura, K., Gimble, J.M., Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). Cytotherapy 15 (2013), 641–648.
    • (2013) Cytotherapy , vol.15 , pp. 641-648
    • Bourin, P.1    Bunnell, B.A.2    Casteilla, L.3    Dominici, M.4    Katz, A.J.5    March, K.L.6    Redl, H.7    Rubin, J.P.8    Yoshimura, K.9    Gimble, J.M.10
  • 25
    • 33750292972 scopus 로고    scopus 로고
    • Cell death in the nervous system
    • Bredesen, D.E., Rao, R.V., Mehlen, P., Cell death in the nervous system. Nature 443 (2006), 796–802.
    • (2006) Nature , vol.443 , pp. 796-802
    • Bredesen, D.E.1    Rao, R.V.2    Mehlen, P.3
  • 30
    • 33750728409 scopus 로고    scopus 로고
    • Stem cells: the good, bad and barely in control
    • Carson, C.T., Aigner, S., Gage, F.H., Stem cells: the good, bad and barely in control. Nat. Med. 12 (2006), 1237–1238.
    • (2006) Nat. Med. , vol.12 , pp. 1237-1238
    • Carson, C.T.1    Aigner, S.2    Gage, F.H.3
  • 31
    • 70349783914 scopus 로고    scopus 로고
    • Dopamine systems in the forebrain
    • Cave, J.W., Baker, H., Dopamine systems in the forebrain. Adv. Exp. Med. Biol. 651 (2009), 15–35.
    • (2009) Adv. Exp. Med. Biol. , vol.651 , pp. 15-35
    • Cave, J.W.1    Baker, H.2
  • 32
    • 84898034558 scopus 로고    scopus 로고
    • Adult subventricular zone neural stem cells as a potential source of dopaminergic replacement neurons
    • Cave, J.W., Wang, M., Baker, H., Adult subventricular zone neural stem cells as a potential source of dopaminergic replacement neurons. Front. Neurosci., 8, 2014, 16.
    • (2014) Front. Neurosci. , vol.8 , pp. 16
    • Cave, J.W.1    Wang, M.2    Baker, H.3
  • 35
    • 84871844339 scopus 로고    scopus 로고
    • Umbilical cord-derived mesenchymal stem cells for hematopoietic stem cell transplantation
    • Chao, Y.H., Wu, H.P., Chan, C.K., Tsai, C., Peng, C.T., Wu, K.H., Umbilical cord-derived mesenchymal stem cells for hematopoietic stem cell transplantation. J. Biomed. Biotechnol., 2012, 2012, 759503.
    • (2012) J. Biomed. Biotechnol. , vol.2012 , pp. 759503
    • Chao, Y.H.1    Wu, H.P.2    Chan, C.K.3    Tsai, C.4    Peng, C.T.5    Wu, K.H.6
  • 38
    • 34548033977 scopus 로고    scopus 로고
    • Age-related decrease of striatal neurogenesis is associated with apoptosis of neural precursors and newborn neurons in rat brain after ischemia
    • Chen, Y., Sun, F.Y., Age-related decrease of striatal neurogenesis is associated with apoptosis of neural precursors and newborn neurons in rat brain after ischemia. Brain Res. 1166 (2007), 9–19.
    • (2007) Brain Res. , vol.1166 , pp. 9-19
    • Chen, Y.1    Sun, F.Y.2
  • 39
    • 84890344147 scopus 로고    scopus 로고
    • Multiple cell transplantation based on an intraparenchymal approach for patients with chronic phase stroke
    • Chen, L., Xi, H., Huang, H., Zhang, F., Liu, Y., Chen, D., Xiao, J., Multiple cell transplantation based on an intraparenchymal approach for patients with chronic phase stroke. Cell Transplant. 22:Suppl. 1 (2013), S83–91.
    • (2013) Cell Transplant. , vol.22 , pp. S83-91
    • Chen, L.1    Xi, H.2    Huang, H.3    Zhang, F.4    Liu, Y.5    Chen, D.6    Xiao, J.7
  • 42
    • 84898959114 scopus 로고    scopus 로고
    • Neural stem cell transplantation improves spatial learning and memory via neuronal regeneration in amyloid-beta precursor protein/presenilin 1/tau triple transgenic mice
    • Chen, S.Q., Cai, Q., Shen, Y.Y., Wang, P.Y., Li, M.H., Teng, G.Y., Neural stem cell transplantation improves spatial learning and memory via neuronal regeneration in amyloid-beta precursor protein/presenilin 1/tau triple transgenic mice. Am. J. Alzheimers Dis. Other Demen. 29 (2014), 142–149.
    • (2014) Am. J. Alzheimers Dis. Other Demen. , vol.29 , pp. 142-149
    • Chen, S.Q.1    Cai, Q.2    Shen, Y.Y.3    Wang, P.Y.4    Li, M.H.5    Teng, G.Y.6
  • 43
    • 77952926102 scopus 로고    scopus 로고
    • Clinical progression in Parkinson disease and the neurobiology of axons
    • Cheng, H.C., Ulane, C.M., Burke, R.E., Clinical progression in Parkinson disease and the neurobiology of axons. Ann. Neurol. 67 (2010), 715–725.
    • (2010) Ann. Neurol. , vol.67 , pp. 715-725
    • Cheng, H.C.1    Ulane, C.M.2    Burke, R.E.3
  • 44
    • 84919663103 scopus 로고    scopus 로고
    • Human umbilical cord mesenchymal stem cells protect against ischemic brain injury in mouse by regulating peripheral immunoinflammation
    • Cheng, Q., Zhang, Z., Zhang, S., Yang, H., Zhang, X., Pan, J., Weng, L., Sha, D., Zhu, M., Hu, X., Xu, Y., Human umbilical cord mesenchymal stem cells protect against ischemic brain injury in mouse by regulating peripheral immunoinflammation. Brain Res. 1594 (2015), 293–304.
    • (2015) Brain Res. , vol.1594 , pp. 293-304
    • Cheng, Q.1    Zhang, Z.2    Zhang, S.3    Yang, H.4    Zhang, X.5    Pan, J.6    Weng, L.7    Sha, D.8    Zhu, M.9    Hu, X.10    Xu, Y.11
  • 45
    • 33745775733 scopus 로고    scopus 로고
    • Stem cell research: the California experience
    • Chiu, A.Y., Hall, Z.W., Stem cell research: the California experience. J. Neurosci. 26 (2006), 6661–6663.
    • (2006) J. Neurosci. , vol.26 , pp. 6661-6663
    • Chiu, A.Y.1    Hall, Z.W.2
  • 46
    • 80955143473 scopus 로고    scopus 로고
    • Cell-based therapy for neural disorders–anticipating challenges
    • Chiu, A.Y., Rao, M.S., Cell-based therapy for neural disorders–anticipating challenges. Neurotherapeutics 8 (2011), 744–752.
    • (2011) Neurotherapeutics , vol.8 , pp. 744-752
    • Chiu, A.Y.1    Rao, M.S.2
  • 48
    • 84880933248 scopus 로고    scopus 로고
    • A comparison of neurosphere differentiation potential of canine bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells
    • Chung, C.S., Fujita, N., Kawahara, N., Yui, S., Nam, E., Nishimura, R., A comparison of neurosphere differentiation potential of canine bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells. J. Vet. Med. Sci. 75 (2013), 879–886.
    • (2013) J. Vet. Med. Sci. , vol.75 , pp. 879-886
    • Chung, C.S.1    Fujita, N.2    Kawahara, N.3    Yui, S.4    Nam, E.5    Nishimura, R.6
  • 49
    • 84911489185 scopus 로고    scopus 로고
    • How can you mend a broken brain? Neurorestorative approaches to stroke recovery
    • Corbett, D., Nguemeni, C., Gomez-Smith, M., How can you mend a broken brain? Neurorestorative approaches to stroke recovery. Cerebrovasc. Dis. 38 (2014), 233–239.
    • (2014) Cerebrovasc. Dis. , vol.38 , pp. 233-239
    • Corbett, D.1    Nguemeni, C.2    Gomez-Smith, M.3
  • 50
    • 84864122244 scopus 로고    scopus 로고
    • Transplantation of umbilical cord-derived mesenchymal stem cells as a novel strategy to protect the central nervous system: technical aspects, preclinical studies, and clinical perspectives
    • Dalous, J., Larghero, J., Baud, O., Transplantation of umbilical cord-derived mesenchymal stem cells as a novel strategy to protect the central nervous system: technical aspects, preclinical studies, and clinical perspectives. Pediatr. Res. 71 (2012), 482–490.
    • (2012) Pediatr. Res. , vol.71 , pp. 482-490
    • Dalous, J.1    Larghero, J.2    Baud, O.3
  • 52
    • 84903521029 scopus 로고    scopus 로고
    • Aging causes exacerbated ischemic brain injury and failure of sevoflurane post-conditioning: role of B-cell lymphoma-2
    • Dong, P., Zhao, J., Zhang, Y., Dong, J., Zhang, L., Li, D., Li, L., Zhang, X., Yang, B., Lei, W., Aging causes exacerbated ischemic brain injury and failure of sevoflurane post-conditioning: role of B-cell lymphoma-2. Neuroscience 275 (2014), 2–11.
    • (2014) Neuroscience , vol.275 , pp. 2-11
    • Dong, P.1    Zhao, J.2    Zhang, Y.3    Dong, J.4    Zhang, L.5    Li, D.6    Li, L.7    Zhang, X.8    Yang, B.9    Lei, W.10
  • 54
    • 84908702702 scopus 로고    scopus 로고
    • Stem cell therapies for Parkinson's disease: are trials just around the corner?
    • Drouin-Ouellet, J., Barker, R.A., Stem cell therapies for Parkinson's disease: are trials just around the corner?. Regen. Med. 9 (2014), 553–555.
    • (2014) Regen. Med. , vol.9 , pp. 553-555
    • Drouin-Ouellet, J.1    Barker, R.A.2
  • 55
    • 84906056329 scopus 로고    scopus 로고
    • Comparison of administration routes for adipose-derived stem cells in the treatment of middle cerebral artery occlusion in rats
    • Du, G., Liu, Y., Dang, M., Zhu, G., Su, R., Fan, Y., Tan, Z., Wang, L.X., Fang, J., Comparison of administration routes for adipose-derived stem cells in the treatment of middle cerebral artery occlusion in rats. Acta Histochem. 116 (2014), 1075–1084.
    • (2014) Acta Histochem. , vol.116 , pp. 1075-1084
    • Du, G.1    Liu, Y.2    Dang, M.3    Zhu, G.4    Su, R.5    Fan, Y.6    Tan, Z.7    Wang, L.X.8    Fang, J.9
  • 58
    • 84898035954 scopus 로고    scopus 로고
    • Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease
    • Garcia, K.O., Ornellas, F.L., Martin, P.K., Patti, C.L., Mello, L.E., Frussa-Filho, R., Han, S.W., Longo, B.M., Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease. Front. Aging Neurosci., 6, 2014, 30.
    • (2014) Front. Aging Neurosci. , vol.6 , pp. 30
    • Garcia, K.O.1    Ornellas, F.L.2    Martin, P.K.3    Patti, C.L.4    Mello, L.E.5    Frussa-Filho, R.6    Han, S.W.7    Longo, B.M.8
  • 59
    • 84877316680 scopus 로고    scopus 로고
    • Cell and gene therapy in Alzheimer's disease
    • Glat, M.J., Offen, D., Cell and gene therapy in Alzheimer's disease. Stem Cells Dev. 22 (2013), 1490–1496.
    • (2013) Stem Cells Dev. , vol.22 , pp. 1490-1496
    • Glat, M.J.1    Offen, D.2
  • 60
    • 0035409575 scopus 로고    scopus 로고
    • Alpha-synuclein and neurodegenerative diseases
    • Goedert, M., Alpha-synuclein and neurodegenerative diseases. Nat. Rev. Neurosci. 2 (2001), 492–501.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 492-501
    • Goedert, M.1
  • 63
    • 84893761684 scopus 로고    scopus 로고
    • In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease model
    • Guo, Z., Zhang, L., Wu, Z., Chen, Y., Wang, F., Chen, G., In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease model. Cell Stem Cell 14 (2014), 188–202.
    • (2014) Cell Stem Cell , vol.14 , pp. 188-202
    • Guo, Z.1    Zhang, L.2    Wu, Z.3    Chen, Y.4    Wang, F.5    Chen, G.6
  • 64
    • 84873353375 scopus 로고    scopus 로고
    • Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke
    • Gutierrez-Fernandez, M., Rodriguez-Frutos, B., Ramos-Cejudo, J., Teresa Vallejo-Cremades, M., Fuentes, B., Cerdan, S., Diez-Tejedor, E., Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke. Stem Cell Res. Ther., 4, 2013, 11.
    • (2013) Stem Cell Res. Ther. , vol.4 , pp. 11
    • Gutierrez-Fernandez, M.1    Rodriguez-Frutos, B.2    Ramos-Cejudo, J.3    Teresa Vallejo-Cremades, M.4    Fuentes, B.5    Cerdan, S.6    Diez-Tejedor, E.7
  • 66
    • 77949897463 scopus 로고    scopus 로고
    • The progression of pathology in Parkinson's disease
    • Halliday, G.M., McCann, H., The progression of pathology in Parkinson's disease. Ann. N. Y. Acad. Sci. 1184 (2010), 188–195.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1184 , pp. 188-195
    • Halliday, G.M.1    McCann, H.2
  • 68
    • 77956846111 scopus 로고    scopus 로고
    • An introduction to induced pluripotent stem cells
    • Hanley, J., Rastegarlari, G., Nathwani, A.C., An introduction to induced pluripotent stem cells. Br. J. Haematol. 151 (2010), 16–24.
    • (2010) Br. J. Haematol. , vol.151 , pp. 16-24
    • Hanley, J.1    Rastegarlari, G.2    Nathwani, A.C.3
  • 69
    • 84962897498 scopus 로고    scopus 로고
    • Insights into the biology and therapeutic applications of neural stem cells
    • Harris, L., Zalucki, O., Piper, M., Heng, J.I., Insights into the biology and therapeutic applications of neural stem cells. Stem Cells Int., 2016, 2016, 9745315.
    • (2016) Stem Cells Int. , vol.2016 , pp. 9745315
    • Harris, L.1    Zalucki, O.2    Piper, M.3    Heng, J.I.4
  • 70
    • 84877610273 scopus 로고    scopus 로고
    • Autophagy in aging and aging-associated diseases
    • He, L.Q., Lu, J.H., Yue, Z.Y., Autophagy in aging and aging-associated diseases. Acta Pharmacol. Sin. 34 (2013), 605–611.
    • (2013) Acta Pharmacol. Sin. , vol.34 , pp. 605-611
    • He, L.Q.1    Lu, J.H.2    Yue, Z.Y.3
  • 71
    • 84879077265 scopus 로고    scopus 로고
    • Alzheimer disease in the United States (2010–2050) estimated using the 2010 census
    • Hebert, L.E., Weuve, J., Scherr, P.A., Evans, D.A., Alzheimer disease in the United States (2010–2050) estimated using the 2010 census. Neurology 80 (2013), 1778–1783.
    • (2013) Neurology , vol.80 , pp. 1778-1783
    • Hebert, L.E.1    Weuve, J.2    Scherr, P.A.3    Evans, D.A.4
  • 74
    • 79956188417 scopus 로고    scopus 로고
    • Mesenchymal stem cells and progenitor cells in connective tissue engineering and regenerative medicine: is there a future for transplantation?
    • Hilfiker, A., Kasper, C., Hass, R., Haverich, A., Mesenchymal stem cells and progenitor cells in connective tissue engineering and regenerative medicine: is there a future for transplantation?. Langenbecks Arch. Surg. 396 (2011), 489–497.
    • (2011) Langenbecks Arch. Surg. , vol.396 , pp. 489-497
    • Hilfiker, A.1    Kasper, C.2    Hass, R.3    Haverich, A.4
  • 75
    • 77949407188 scopus 로고    scopus 로고
    • Ageing, neurodegeneration and Parkinson's disease
    • Hindle, J.V., Ageing, neurodegeneration and Parkinson's disease. Age Ageing 39 (2010), 156–161.
    • (2010) Age Ageing , vol.39 , pp. 156-161
    • Hindle, J.V.1
  • 76
    • 3042706276 scopus 로고    scopus 로고
    • Lost in translation: taking neuroprotection from animal models to clinical trials
    • Hoyte, L., Kaur, J., Buchan, A.M., Lost in translation: taking neuroprotection from animal models to clinical trials. Exp. Neurol. 188 (2004), 200–204.
    • (2004) Exp. Neurol. , vol.188 , pp. 200-204
    • Hoyte, L.1    Kaur, J.2    Buchan, A.M.3
  • 77
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • Huang, Y., Mucke, L., Alzheimer mechanisms and therapeutic strategies. Cell 148 (2012), 1204–1222.
    • (2012) Cell , vol.148 , pp. 1204-1222
    • Huang, Y.1    Mucke, L.2
  • 78
    • 34748845732 scopus 로고    scopus 로고
    • Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis
    • Hung, S.C., Pochampally, R.R., Chen, S.C., Hsu, S.C., Prockop, D.J., Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis. Stem Cells 25 (2007), 2363–2370.
    • (2007) Stem Cells , vol.25 , pp. 2363-2370
    • Hung, S.C.1    Pochampally, R.R.2    Chen, S.C.3    Hsu, S.C.4    Prockop, D.J.5
  • 83
    • 34848848202 scopus 로고    scopus 로고
    • Erythropoietin promotes neuronal replacement through revascularization and neurogenesis after neonatal hypoxia/ischemia in rats
    • Iwai, M., Cao, G., Yin, W., Stetler, R.A., Liu, J., Chen, J., Erythropoietin promotes neuronal replacement through revascularization and neurogenesis after neonatal hypoxia/ischemia in rats. Stroke 38 (2007), 2795–2803.
    • (2007) Stroke , vol.38 , pp. 2795-2803
    • Iwai, M.1    Cao, G.2    Yin, W.3    Stetler, R.A.4    Liu, J.5    Chen, J.6
  • 85
    • 84890424686 scopus 로고    scopus 로고
    • Feasibility of delivering mesenchymal stem cells via catheter to the proximal end of the lesion artery in patients with stroke in the territory of the middle cerebral artery
    • Jiang, Y., Zhu, W., Zhu, J., Wu, L., Xu, G., Liu, X., Feasibility of delivering mesenchymal stem cells via catheter to the proximal end of the lesion artery in patients with stroke in the territory of the middle cerebral artery. Cell Transplant. 22 (2013), 2291–2298.
    • (2013) Cell Transplant. , vol.22 , pp. 2291-2298
    • Jiang, Y.1    Zhu, W.2    Zhu, J.3    Wu, L.4    Xu, G.5    Liu, X.6
  • 86
    • 84991025400 scopus 로고    scopus 로고
    • Aging affects new cell production in the adult hippocampus: a quantitative anatomic review
    • Jinno, S., Aging affects new cell production in the adult hippocampus: a quantitative anatomic review. J. Chem. Neuroanat., 2015.
    • (2015) J. Chem. Neuroanat.
    • Jinno, S.1
  • 87
    • 34547607603 scopus 로고    scopus 로고
    • Autotransplantation of bone marrow-derived stem cells as a therapy for neurodegenerative diseases
    • Kan, I., Melamed, E., Offen, D., Autotransplantation of bone marrow-derived stem cells as a therapy for neurodegenerative diseases. Handb. Exp. Pharmacol., 2007, 219–242.
    • (2007) Handb. Exp. Pharmacol. , pp. 219-242
    • Kan, I.1    Melamed, E.2    Offen, D.3
  • 88
    • 79954999836 scopus 로고    scopus 로고
    • Mesenchymal stem cells stimulate endogenous neurogenesis in the subventricular zone of adult mice
    • Kan, I., Barhum, Y., Melamed, E., Offen, D., Mesenchymal stem cells stimulate endogenous neurogenesis in the subventricular zone of adult mice. Stem Cell Rev. 7 (2011), 404–412.
    • (2011) Stem Cell Rev. , vol.7 , pp. 404-412
    • Kan, I.1    Barhum, Y.2    Melamed, E.3    Offen, D.4
  • 89
    • 84870892437 scopus 로고    scopus 로고
    • Clinical experience with stem cells and other cell therapies in neurological diseases
    • Karussis, D., Petrou, P., Kassis, I., Clinical experience with stem cells and other cell therapies in neurological diseases. J. Neurol. Sci. 324 (2013), 1–9.
    • (2013) J. Neurol. Sci. , vol.324 , pp. 1-9
    • Karussis, D.1    Petrou, P.2    Kassis, I.3
  • 90
    • 84883807360 scopus 로고    scopus 로고
    • Can we teach old dogs new tricks? Neuroprotective cell therapy in Alzheimer's and Parkinson's disease
    • Kazmerova, Z., Zilka, N., Cente, M., Neradil, P., Zilkova, M., Novak, M., Can we teach old dogs new tricks? Neuroprotective cell therapy in Alzheimer's and Parkinson's disease. J. Alzheimers Dis. 37 (2013), 251–272.
    • (2013) J. Alzheimers Dis. , vol.37 , pp. 251-272
    • Kazmerova, Z.1    Zilka, N.2    Cente, M.3    Neradil, P.4    Zilkova, M.5    Novak, M.6
  • 91
    • 34249666071 scopus 로고    scopus 로고
    • Effect of human embryonic stem cell-derived neuronal precursor cell transplantation into the cerebral infarct model of rat with exercise
    • Kim, D.Y., Park, S.H., Lee, S.U., Choi, D.H., Park, H.W., Paek, S.H., Shin, H.Y., Kim, E.Y., Park, S.P., Lim, J.H., Effect of human embryonic stem cell-derived neuronal precursor cell transplantation into the cerebral infarct model of rat with exercise. Neurosci. Res. 58 (2007), 164–175.
    • (2007) Neurosci. Res. , vol.58 , pp. 164-175
    • Kim, D.Y.1    Park, S.H.2    Lee, S.U.3    Choi, D.H.4    Park, H.W.5    Paek, S.H.6    Shin, H.Y.7    Kim, E.Y.8    Park, S.P.9    Lim, J.H.10
  • 92
    • 84866862490 scopus 로고    scopus 로고
    • The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice
    • Kim, S., Chang, K.A., Kim, J., Park, H.G., Ra, J.C., Kim, H.S., Suh, Y.H., The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice. PLoS One, 7, 2012, e45757.
    • (2012) PLoS One , vol.7 , pp. e45757
    • Kim, S.1    Chang, K.A.2    Kim, J.3    Park, H.G.4    Ra, J.C.5    Kim, H.S.6    Suh, Y.H.7
  • 93
    • 84884788312 scopus 로고    scopus 로고
    • Intravenous transplantation of mesenchymal stem cells preconditioned with early phase stroke serum: current evidence and study protocol for a randomized trial
    • Kim, S.J., Moon, G.J., Chang, W.H., Kim, Y.H., Bang, O.Y., Intravenous transplantation of mesenchymal stem cells preconditioned with early phase stroke serum: current evidence and study protocol for a randomized trial. Trials, 14, 2013, 317.
    • (2013) Trials , vol.14 , pp. 317
    • Kim, S.J.1    Moon, G.J.2    Chang, W.H.3    Kim, Y.H.4    Bang, O.Y.5
  • 94
    • 84948398738 scopus 로고    scopus 로고
    • Transcriptome sequencing of hematopoietic stem cells and chronic myelgenous leukemia stem cells
    • Kim, J., Kim, S.J., Naka, K., Transcriptome sequencing of hematopoietic stem cells and chronic myelgenous leukemia stem cells. Genomics Data 7 (2016), 57–59.
    • (2016) Genomics Data , vol.7 , pp. 57-59
    • Kim, J.1    Kim, S.J.2    Naka, K.3
  • 95
    • 1842486565 scopus 로고    scopus 로고
    • Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms
    • Kinnaird, T., Stabile, E., Burnett, M.S., Shou, M., Lee, C.W., Barr, S., Fuchs, S., Epstein, S.E., Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 109 (2004), 1543–1549.
    • (2004) Circulation , vol.109 , pp. 1543-1549
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Shou, M.4    Lee, C.W.5    Barr, S.6    Fuchs, S.7    Epstein, S.E.8
  • 97
    • 84897569242 scopus 로고    scopus 로고
    • Adipose stem cells: biology and clinical applications for tissue repair and regeneration
    • Kokai, L.E., Marra, K., Rubin, J.P., Adipose stem cells: biology and clinical applications for tissue repair and regeneration. Transl. Res. 163 (2014), 399–408.
    • (2014) Transl. Res. , vol.163 , pp. 399-408
    • Kokai, L.E.1    Marra, K.2    Rubin, J.P.3
  • 101
    • 77950256736 scopus 로고    scopus 로고
    • The expanding universe of neurotrophic factors: therapeutic potential in aging and age-associated disorders
    • Lanni, C., Stanga, S., Racchi, M., Govoni, S., The expanding universe of neurotrophic factors: therapeutic potential in aging and age-associated disorders. Curr. Pharm. Des. 16 (2010), 698–717.
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 698-717
    • Lanni, C.1    Stanga, S.2    Racchi, M.3    Govoni, S.4
  • 102
    • 84891765078 scopus 로고    scopus 로고
    • From apoplexy to stroke: historical perspectives and new research frontiers
    • Leak, R.K., Zheng, P., Ji, X., Zhang, J.H., Chen, J., From apoplexy to stroke: historical perspectives and new research frontiers. Prog. Neurobiol. 115 (2014), 1–5.
    • (2014) Prog. Neurobiol. , vol.115 , pp. 1-5
    • Leak, R.K.1    Zheng, P.2    Ji, X.3    Zhang, J.H.4    Chen, J.5
  • 103
    • 58149333136 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model
    • Lee, J.K., Jin, H.K., Bae, J.S., Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model. Neurosci. Lett. 450 (2009), 136–141.
    • (2009) Neurosci. Lett. , vol.450 , pp. 136-141
    • Lee, J.K.1    Jin, H.K.2    Bae, J.S.3
  • 104
    • 77955087538 scopus 로고    scopus 로고
    • The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease
    • Lee, H.J., Lee, J.K., Lee, H., Shin, J.W., Carter, J.E., Sakamoto, T., Jin, H.K., Bae, J.S., The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease. Neurosci. Lett. 481 (2010), 30–35.
    • (2010) Neurosci. Lett. , vol.481 , pp. 30-35
    • Lee, H.J.1    Lee, J.K.2    Lee, H.3    Shin, J.W.4    Carter, J.E.5    Sakamoto, T.6    Jin, H.K.7    Bae, J.S.8
  • 105
    • 77149146814 scopus 로고    scopus 로고
    • Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease mice by modulation of immune responses
    • Lee, J.K., Jin, H.K., Endo, S., Schuchman, E.H., Carter, J.E., Bae, J.S., Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease mice by modulation of immune responses. Stem Cells 28 (2010), 329–343.
    • (2010) Stem Cells , vol.28 , pp. 329-343
    • Lee, J.K.1    Jin, H.K.2    Endo, S.3    Schuchman, E.H.4    Carter, J.E.5    Bae, J.S.6
  • 106
    • 84862842013 scopus 로고    scopus 로고
    • Soluble CCL5 derived from bone marrow-derived mesenchymal stem cells and activated by amyloid beta ameliorates Alzheimer's disease in mice by recruiting bone marrow-induced microglia immune responses
    • Lee, J.K., Schuchman, E.H., Jin, H.K., Bae, J.S., Soluble CCL5 derived from bone marrow-derived mesenchymal stem cells and activated by amyloid beta ameliorates Alzheimer's disease in mice by recruiting bone marrow-induced microglia immune responses. Stem Cells 30 (2012), 1544–1555.
    • (2012) Stem Cells , vol.30 , pp. 1544-1555
    • Lee, J.K.1    Schuchman, E.H.2    Jin, H.K.3    Bae, J.S.4
  • 107
    • 77649271334 scopus 로고    scopus 로고
    • Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study
    • Li, L., Jiang, Q., Ding, G., Zhang, L., Zhang, Z.G., Li, Q., Panda, S., Lu, M., Ewing, J.R., Chopp, M., Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study. J. Cereb. Blood Flow Metab. 30 (2010), 653–662.
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 653-662
    • Li, L.1    Jiang, Q.2    Ding, G.3    Zhang, L.4    Zhang, Z.G.5    Li, Q.6    Panda, S.7    Lu, M.8    Ewing, J.R.9    Chopp, M.10
  • 108
    • 84924407140 scopus 로고    scopus 로고
    • Intranasal delivery of stem cells as therapy for central nervous system disease
    • Li, Y.H., Feng, L., Zhang, G.X., Ma, C.G., Intranasal delivery of stem cells as therapy for central nervous system disease. Exp. Mol. Pathol. 98 (2015), 145–151.
    • (2015) Exp. Mol. Pathol. , vol.98 , pp. 145-151
    • Li, Y.H.1    Feng, L.2    Zhang, G.X.3    Ma, C.G.4
  • 110
    • 68349160764 scopus 로고    scopus 로고
    • Therapeutic benefit of human umbilical cord derived mesenchymal stromal cells in intracerebral hemorrhage rat: implications of anti-inflammation and angiogenesis
    • Liao, W., Zhong, J., Yu, J., Xie, J., Liu, Y., Du, L., Yang, S., Liu, P., Xu, J., Wang, J., Han, Z., Han, Z.C., Therapeutic benefit of human umbilical cord derived mesenchymal stromal cells in intracerebral hemorrhage rat: implications of anti-inflammation and angiogenesis. Cell. Physiol. Biochem. 24 (2009), 307–316.
    • (2009) Cell. Physiol. Biochem. , vol.24 , pp. 307-316
    • Liao, W.1    Zhong, J.2    Yu, J.3    Xie, J.4    Liu, Y.5    Du, L.6    Yang, S.7    Liu, P.8    Xu, J.9    Wang, J.10    Han, Z.11    Han, Z.C.12
  • 111
    • 79955038911 scopus 로고    scopus 로고
    • The potential of adipose stem cells in regenerative medicine
    • Lindroos, B., Suuronen, R., Miettinen, S., The potential of adipose stem cells in regenerative medicine. Stem Cell Rev. 7 (2011), 269–291.
    • (2011) Stem Cell Rev. , vol.7 , pp. 269-291
    • Lindroos, B.1    Suuronen, R.2    Miettinen, S.3
  • 113
    • 84860193946 scopus 로고    scopus 로고
    • Intranasal delivery of biologics to the central nervous system
    • Lochhead, J.J., Thorne, R.G., Intranasal delivery of biologics to the central nervous system. Adv. Drug Deliv. Rev. 64 (2012), 614–628.
    • (2012) Adv. Drug Deliv. Rev. , vol.64 , pp. 614-628
    • Lochhead, J.J.1    Thorne, R.G.2
  • 114
    • 84890377367 scopus 로고    scopus 로고
    • Intracerebral transplantation of adipose-derived mesenchymal stem cells alternatively activates microglia and ameliorates neuropathological deficits in Alzheimer's disease mice
    • Ma, T., Gong, K., Ao, Q., Yan, Y., Song, B., Huang, H., Zhang, X., Gong, Y., Intracerebral transplantation of adipose-derived mesenchymal stem cells alternatively activates microglia and ameliorates neuropathological deficits in Alzheimer's disease mice. Cell Transplant. 22:Suppl. 1 (2013), S113–126.
    • (2013) Cell Transplant. , vol.22 , pp. S113-126
    • Ma, T.1    Gong, K.2    Ao, Q.3    Yan, Y.4    Song, B.5    Huang, H.6    Zhang, X.7    Gong, Y.8
  • 115
    • 0038467307 scopus 로고    scopus 로고
    • Marked loss of myelinated nerve fibers in the human brain with age
    • Marner, L., Nyengaard, J.R., Tang, Y., Pakkenberg, B., Marked loss of myelinated nerve fibers in the human brain with age. J. Comp. Neurol. 462 (2003), 144–152.
    • (2003) J. Comp. Neurol. , vol.462 , pp. 144-152
    • Marner, L.1    Nyengaard, J.R.2    Tang, Y.3    Pakkenberg, B.4
  • 118
    • 84856073417 scopus 로고    scopus 로고
    • The effect of two- and three-dimensional cell culture on the chondrogenic potential of human adipose-derived mesenchymal stem cells after subcutaneous transplantation with an injectable hydrogel
    • Merceron, C., Portron, S., Masson, M., Lesoeur, J., Fellah, B.H., Gauthier, O., Geffroy, O., Weiss, P., Guicheux, J., Vinatier, C., The effect of two- and three-dimensional cell culture on the chondrogenic potential of human adipose-derived mesenchymal stem cells after subcutaneous transplantation with an injectable hydrogel. Cell Transplant. 20 (2011), 1575–1588.
    • (2011) Cell Transplant. , vol.20 , pp. 1575-1588
    • Merceron, C.1    Portron, S.2    Masson, M.3    Lesoeur, J.4    Fellah, B.H.5    Gauthier, O.6    Geffroy, O.7    Weiss, P.8    Guicheux, J.9    Vinatier, C.10
  • 119
    • 79956209852 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian brain: significant answers and significant questions
    • Ming, G.L., Song, H., Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70 (2011), 687–702.
    • (2011) Neuron , vol.70 , pp. 687-702
    • Ming, G.L.1    Song, H.2
  • 120
    • 84867545489 scopus 로고    scopus 로고
    • Stem cell therapy in ischemic stroke: role of IV and intra-arterial therapy
    • Misra, V., Ritchie, M.M., Stone, L.L., Low, W.C., Janardhan, V., Stem cell therapy in ischemic stroke: role of IV and intra-arterial therapy. Neurology 79 (2012), S207–212.
    • (2012) Neurology , vol.79 , pp. S207-212
    • Misra, V.1    Ritchie, M.M.2    Stone, L.L.3    Low, W.C.4    Janardhan, V.5
  • 124
    • 84937159590 scopus 로고    scopus 로고
    • Adult human neural stem cell therapeutics: current developmental status and prospect
    • Nam, H., Lee, K.H., Nam, D.H., Joo, K.M., Adult human neural stem cell therapeutics: current developmental status and prospect. World J. Stem Cells 7 (2015), 126–136.
    • (2015) World J. Stem Cells , vol.7 , pp. 126-136
    • Nam, H.1    Lee, K.H.2    Nam, D.H.3    Joo, K.M.4
  • 125
    • 84885174320 scopus 로고    scopus 로고
    • In vivo reprogramming of astrocytes to neuroblasts in the adult brain
    • Niu, W., Zang, T., Zou, Y., Fang, S., Smith, D.K., Bachoo, R., Zhang, C.L., In vivo reprogramming of astrocytes to neuroblasts in the adult brain. Nat. Cell Biol. 15 (2013), 1164–1175.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 1164-1175
    • Niu, W.1    Zang, T.2    Zou, Y.3    Fang, S.4    Smith, D.K.5    Bachoo, R.6    Zhang, C.L.7
  • 126
    • 33845656103 scopus 로고    scopus 로고
    • A neurovascular niche for neurogenesis after stroke
    • Ohab, J.J., Fleming, S., Blesch, A., Carmichael, S.T., A neurovascular niche for neurogenesis after stroke. J. Neurosci. 26 (2006), 13007–13016.
    • (2006) J. Neurosci. , vol.26 , pp. 13007-13016
    • Ohab, J.J.1    Fleming, S.2    Blesch, A.3    Carmichael, S.T.4
  • 127
    • 0037413659 scopus 로고    scopus 로고
    • Dissociative increase of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia
    • Ohta, K., Iwai, M., Sato, K., Omori, N., Nagano, I., Shoji, M., Abe, K., Dissociative increase of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia. Neurosci. Lett. 335 (2003), 159–162.
    • (2003) Neurosci. Lett. , vol.335 , pp. 159-162
    • Ohta, K.1    Iwai, M.2    Sato, K.3    Omori, N.4    Nagano, I.5    Shoji, M.6    Abe, K.7
  • 128
    • 84876464760 scopus 로고    scopus 로고
    • Adipose-derived stem cells: fatty potentials for therapy
    • Ong, W.K., Sugii, S., Adipose-derived stem cells: fatty potentials for therapy. Int. J. Biochem. Cell Biol. 45 (2013), 1083–1086.
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , pp. 1083-1086
    • Ong, W.K.1    Sugii, S.2
  • 131
    • 84955559166 scopus 로고    scopus 로고
    • Cartilage regeneration in human with adipose tissue-derived stem cells: current status in clinical implications
    • Pak, J., Lee, J.H., Kartolo, W.A., Lee, S.H., Cartilage regeneration in human with adipose tissue-derived stem cells: current status in clinical implications. BioMed Res. Int., 2016, 2016, 4702674.
    • (2016) BioMed Res. Int. , vol.2016 , pp. 4702674
    • Pak, J.1    Lee, J.H.2    Kartolo, W.A.3    Lee, S.H.4
  • 133
    • 20344398223 scopus 로고    scopus 로고
    • Astrocyte activation and reactive gliosis
    • Pekny, M., Nilsson, M., Astrocyte activation and reactive gliosis. Glia 50 (2005), 427–434.
    • (2005) Glia , vol.50 , pp. 427-434
    • Pekny, M.1    Nilsson, M.2
  • 134
    • 33645874503 scopus 로고    scopus 로고
    • Accelerated delimitation of the infarct zone by capillary-derived nestin-positive cells in aged rats
    • Popa-Wagner, A., Dinca, I., Yalikun, S., Walker, L., Kroemer, H., Kessler, C., Accelerated delimitation of the infarct zone by capillary-derived nestin-positive cells in aged rats. Curr. Neurovasc. Res. 3 (2006), 3–13.
    • (2006) Curr. Neurovasc. Res. , vol.3 , pp. 3-13
    • Popa-Wagner, A.1    Dinca, I.2    Yalikun, S.3    Walker, L.4    Kroemer, H.5    Kessler, C.6
  • 135
    • 33947410259 scopus 로고    scopus 로고
    • Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats
    • Popa-Wagner, A., Badan, I., Walker, L., Groppa, S., Patrana, N., Kessler, C., Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats. Acta Neuropathol. 113 (2007), 277–293.
    • (2007) Acta Neuropathol. , vol.113 , pp. 277-293
    • Popa-Wagner, A.1    Badan, I.2    Walker, L.3    Groppa, S.4    Patrana, N.5    Kessler, C.6
  • 138
    • 84939494398 scopus 로고    scopus 로고
    • A two-year follow-up study of cotransplantation with neural stem/progenitor cells and mesenchymal stromal cells in ischemic stroke patients
    • Qiao, L.Y., Huang, F.J., Zhao, M., Xie, J.H., Shi, J., Wang, J., Lin, X.Z., Zuo, H., Wang, Y.L., Geng, T.C., A two-year follow-up study of cotransplantation with neural stem/progenitor cells and mesenchymal stromal cells in ischemic stroke patients. Cell Transplant. 23:Suppl. 1 (2014), S65–72.
    • (2014) Cell Transplant. , vol.23 , pp. S65-72
    • Qiao, L.Y.1    Huang, F.J.2    Zhao, M.3    Xie, J.H.4    Shi, J.5    Wang, J.6    Lin, X.Z.7    Zuo, H.8    Wang, Y.L.9    Geng, T.C.10
  • 140
    • 78650589408 scopus 로고    scopus 로고
    • Energy metabolism in adult neural stem cell fate
    • Rafalski, V.A., Brunet, A., Energy metabolism in adult neural stem cell fate. Prog. Neurobiol. 93 (2011), 182–203.
    • (2011) Prog. Neurobiol. , vol.93 , pp. 182-203
    • Rafalski, V.A.1    Brunet, A.2
  • 141
    • 84881617975 scopus 로고    scopus 로고
    • Comparing brain-derived neurotrophic factor and ciliary neurotrophic factor secretion of induced neurotrophic factor secreting cells from human adipose and bone marrow-derived stem cells
    • Razavi, S., Razavi, M.R., Zarkesh Esfahani, H., Kazemi, M., Mostafavi, F.S., Comparing brain-derived neurotrophic factor and ciliary neurotrophic factor secretion of induced neurotrophic factor secreting cells from human adipose and bone marrow-derived stem cells. Dev. Growth Differ. 55 (2013), 648–655.
    • (2013) Dev. Growth Differ. , vol.55 , pp. 648-655
    • Razavi, S.1    Razavi, M.R.2    Zarkesh Esfahani, H.3    Kazemi, M.4    Mostafavi, F.S.5
  • 143
    • 78751677843 scopus 로고    scopus 로고
    • The stem cell potential of glia: lessons from reactive gliosis
    • Robel, S., Berninger, B., Gotz, M., The stem cell potential of glia: lessons from reactive gliosis. Nat. Rev. Neurosci. 12 (2011), 88–104.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 88-104
    • Robel, S.1    Berninger, B.2    Gotz, M.3
  • 145
    • 84928236049 scopus 로고    scopus 로고
    • Age-associated changes on axonal regeneration and functional outcome after spinal cord injury in rats
    • Roozbehi, A., Joghataei, M.T., Bakhtiyari, M., Mohammadi, J., Rad, P., Delaviz, H., Age-associated changes on axonal regeneration and functional outcome after spinal cord injury in rats. Acta Med. Iran. 53 (2015), 281–286.
    • (2015) Acta Med. Iran. , vol.53 , pp. 281-286
    • Roozbehi, A.1    Joghataei, M.T.2    Bakhtiyari, M.3    Mohammadi, J.4    Rad, P.5    Delaviz, H.6
  • 146
    • 70450191228 scopus 로고    scopus 로고
    • Bone-marrow-derived mesenchymal stem cell therapy for neurodegenerative diseases
    • Sadan, O., Melamed, E., Offen, D., Bone-marrow-derived mesenchymal stem cell therapy for neurodegenerative diseases. Expert Opin. Biol. Ther. 9 (2009), 1487–1497.
    • (2009) Expert Opin. Biol. Ther. , vol.9 , pp. 1487-1497
    • Sadan, O.1    Melamed, E.2    Offen, D.3
  • 147
    • 67549138948 scopus 로고    scopus 로고
    • Adult neurotrophic factor-secreting stem cells: a potential novel therapy for neurodegenerative diseases
    • Sadan, O., Shemesh, N., Cohen, Y., Melamed, E., Offen, D., Adult neurotrophic factor-secreting stem cells: a potential novel therapy for neurodegenerative diseases. Isr. Med. Assoc. J. 11 (2009), 201–204.
    • (2009) Isr. Med. Assoc. J. , vol.11 , pp. 201-204
    • Sadan, O.1    Shemesh, N.2    Cohen, Y.3    Melamed, E.4    Offen, D.5
  • 148
    • 77950265945 scopus 로고    scopus 로고
    • Linking functional decline of telomeres, mitochondria and stem cells during aging
    • Sahin, E., Depinho, R.A., Linking functional decline of telomeres, mitochondria and stem cells during aging. Nature 464 (2010), 520–528.
    • (2010) Nature , vol.464 , pp. 520-528
    • Sahin, E.1    Depinho, R.A.2
  • 149
    • 84911421913 scopus 로고    scopus 로고
    • Potential of bone marrow mesenchymal stem cells in management of Alzheimer's disease in female rats
    • Salem, A.M., Ahmed, H.H., Atta, H.M., Ghazy, M.A., Aglan, H.A., Potential of bone marrow mesenchymal stem cells in management of Alzheimer's disease in female rats. Cell Biol. Int. 38 (2014), 1367–1383.
    • (2014) Cell Biol. Int. , vol.38 , pp. 1367-1383
    • Salem, A.M.1    Ahmed, H.H.2    Atta, H.M.3    Ghazy, M.A.4    Aglan, H.A.5
  • 150
    • 0037106213 scopus 로고    scopus 로고
    • Neural cells derived from adult bone marrow and umbilical cord blood
    • Sanchez-Ramos, J.R., Neural cells derived from adult bone marrow and umbilical cord blood. J. Neurosci. Res. 69 (2002), 880–893.
    • (2002) J. Neurosci. Res. , vol.69 , pp. 880-893
    • Sanchez-Ramos, J.R.1
  • 152
    • 23844487540 scopus 로고    scopus 로고
    • Neurotransplantation of fetal porcine cells in patients with basal ganglia infarcts: a preliminary safety and feasibility study
    • Savitz, S.I., Dinsmore, J., Wu, J., Henderson, G.V., Stieg, P., Caplan, L.R., Neurotransplantation of fetal porcine cells in patients with basal ganglia infarcts: a preliminary safety and feasibility study. Cerebrovasc. Dis. (Basel Switzerland) 20 (2005), 101–107.
    • (2005) Cerebrovasc. Dis. (Basel Switzerland) , vol.20 , pp. 101-107
    • Savitz, S.I.1    Dinsmore, J.2    Wu, J.3    Henderson, G.V.4    Stieg, P.5    Caplan, L.R.6
  • 154
    • 84941114061 scopus 로고    scopus 로고
    • Clinical and pathological features of Parkinson's disease
    • Schneider, S.A., Obeso, J.A., Clinical and pathological features of Parkinson's disease. Curr. Top. Behav. Neurosci. 22 (2015), 205–220.
    • (2015) Curr. Top. Behav. Neurosci. , vol.22 , pp. 205-220
    • Schneider, S.A.1    Obeso, J.A.2
  • 155
    • 62149098424 scopus 로고    scopus 로고
    • Down-regulation of neurocan expression in reactive astrocytes promotes axonal regeneration and facilitates the neurorestorative effects of bone marrow stromal cells in the ischemic rat brain
    • Shen, L.H., Li, Y., Gao, Q., Savant-Bhonsale, S., Chopp, M., Down-regulation of neurocan expression in reactive astrocytes promotes axonal regeneration and facilitates the neurorestorative effects of bone marrow stromal cells in the ischemic rat brain. Glia 56 (2008), 1747–1754.
    • (2008) Glia , vol.56 , pp. 1747-1754
    • Shen, L.H.1    Li, Y.2    Gao, Q.3    Savant-Bhonsale, S.4    Chopp, M.5
  • 156
    • 84874740862 scopus 로고    scopus 로고
    • Dopaminergic cells, derived from a high efficiency differentiation protocol from umbilical cord derived mesenchymal stem cells, alleviate symptoms in a Parkinson's disease rodent model
    • Shetty, P., Thakur, A.M., Viswanathan, C., Dopaminergic cells, derived from a high efficiency differentiation protocol from umbilical cord derived mesenchymal stem cells, alleviate symptoms in a Parkinson's disease rodent model. Cell Biol. Int. 37 (2013), 167–180.
    • (2013) Cell Biol. Int. , vol.37 , pp. 167-180
    • Shetty, P.1    Thakur, A.M.2    Viswanathan, C.3
  • 157
    • 79960075722 scopus 로고    scopus 로고
    • Combined effects of hematopoietic progenitor cell mobilization from bone marrow by granulocyte colony stimulating factor and AMD3100 and chemotaxis into the brain using stromal cell-derived factor-1alpha in an Alzheimer's disease mouse model
    • Shin, J.W., Lee, J.K., Lee, J.E., Min, W.K., Schuchman, E.H., Jin, H.K., Bae, J.S., Combined effects of hematopoietic progenitor cell mobilization from bone marrow by granulocyte colony stimulating factor and AMD3100 and chemotaxis into the brain using stromal cell-derived factor-1alpha in an Alzheimer's disease mouse model. Stem Cells (Dayton Ohio) 29 (2011), 1075–1089.
    • (2011) Stem Cells (Dayton Ohio) , vol.29 , pp. 1075-1089
    • Shin, J.W.1    Lee, J.K.2    Lee, J.E.3    Min, W.K.4    Schuchman, E.H.5    Jin, H.K.6    Bae, J.S.7
  • 159
    • 33847105184 scopus 로고    scopus 로고
    • Advances in the treatment of Parkinson's disease
    • Singh, N., Pillay, V., Choonara, Y.E., Advances in the treatment of Parkinson's disease. Prog. Neurobiol. 81 (2007), 29–44.
    • (2007) Prog. Neurobiol. , vol.81 , pp. 29-44
    • Singh, N.1    Pillay, V.2    Choonara, Y.E.3
  • 160
    • 79955601033 scopus 로고    scopus 로고
    • Cd34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans
    • Sobrino, T., Arias, S., Perez-Mato, M., Agulla, J., Brea, D., Rodriguez-Yanez, M., Castillo, J., Cd34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans. J. Neurosci. Res. 89 (2011), 979–985.
    • (2011) J. Neurosci. Res. , vol.89 , pp. 979-985
    • Sobrino, T.1    Arias, S.2    Perez-Mato, M.3    Agulla, J.4    Brea, D.5    Rodriguez-Yanez, M.6    Castillo, J.7
  • 162
    • 84943361972 scopus 로고    scopus 로고
    • Being human: the role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer's disease models
    • Sproul, A.A., Being human: the role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer's disease models. Mol. Aspects Med. 43–44 (2015), 54–65.
    • (2015) Mol. Aspects Med. , vol.43-44 , pp. 54-65
    • Sproul, A.A.1
  • 163
    • 22144469750 scopus 로고    scopus 로고
    • Possible use of autologous stem cell therapies for Alzheimer's disease
    • Sugaya, K., Possible use of autologous stem cell therapies for Alzheimer's disease. Curr. Alzheimer Res. 2 (2005), 367–376.
    • (2005) Curr. Alzheimer Res. , vol.2 , pp. 367-376
    • Sugaya, K.1
  • 164
    • 79952423223 scopus 로고    scopus 로고
    • Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells
    • Sugii, S., Kida, Y., Berggren, W.T., Evans, R.M., Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells. Nat. Protoc. 6 (2011), 346–358.
    • (2011) Nat. Protoc. , vol.6 , pp. 346-358
    • Sugii, S.1    Kida, Y.2    Berggren, W.T.3    Evans, R.M.4
  • 165
    • 33746705523 scopus 로고    scopus 로고
    • Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease
    • Suon, S., Yang, M., Iacovitti, L., Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease. Brain Res. 1106 (2006), 46–51.
    • (2006) Brain Res. , vol.1106 , pp. 46-51
    • Suon, S.1    Yang, M.2    Iacovitti, L.3
  • 167
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K., Yamanaka, S., Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006), 663–676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 169
    • 84925348811 scopus 로고    scopus 로고
    • Opportunities and challenges: stem cell-based therapy for the treatment of ischemic stroke
    • Tang, Y.H., Ma, Y.Y., Zhang, Z.J., Wang, Y.T., Yang, G.Y., Opportunities and challenges: stem cell-based therapy for the treatment of ischemic stroke. CNS Neurosci. Ther. 21 (2015), 337–347.
    • (2015) CNS Neurosci. Ther. , vol.21 , pp. 337-347
    • Tang, Y.H.1    Ma, Y.Y.2    Zhang, Z.J.3    Wang, Y.T.4    Yang, G.Y.5
  • 170
    • 34248177735 scopus 로고    scopus 로고
    • Current advances in the treatment of Parkinson's disease with stem cells
    • Trzaska, K.A., Rameshwar, P., Current advances in the treatment of Parkinson's disease with stem cells. Curr. Neurovasc. Res. 4 (2007), 99–109.
    • (2007) Curr. Neurovasc. Res. , vol.4 , pp. 99-109
    • Trzaska, K.A.1    Rameshwar, P.2
  • 174
    • 84906789750 scopus 로고    scopus 로고
    • White matter plasticity in adulthood
    • Wang, S., Young, K.M., White matter plasticity in adulthood. Neuroscience 276 (2014), 148–160.
    • (2014) Neuroscience , vol.276 , pp. 148-160
    • Wang, S.1    Young, K.M.2
  • 175
    • 84877154299 scopus 로고    scopus 로고
    • PET demonstrates functional recovery after transplantation of induced pluripotent stem cells in a rat model of cerebral ischemic injury
    • Wang, J., Chao, F., Han, F., Zhang, G., Xi, Q., Li, J., Jiang, H., Wang, J., Yu, G., Tian, M., Zhang, H., PET demonstrates functional recovery after transplantation of induced pluripotent stem cells in a rat model of cerebral ischemic injury. J. Nucl. Med. 54 (2013), 785–792.
    • (2013) J. Nucl. Med. , vol.54 , pp. 785-792
    • Wang, J.1    Chao, F.2    Han, F.3    Zhang, G.4    Xi, Q.5    Li, J.6    Jiang, H.7    Wang, J.8    Yu, G.9    Tian, M.10    Zhang, H.11
  • 176
    • 84937901189 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells ameliorate neurological deficits and blood-brain barrier dysfunction after intracerebral hemorrhage in spontaneously hypertensive rats
    • Wang, C., Fei, Y., Xu, C., Zhao, Y., Pan, Y., Bone marrow mesenchymal stem cells ameliorate neurological deficits and blood-brain barrier dysfunction after intracerebral hemorrhage in spontaneously hypertensive rats. Int. J. Clin. Exp. Pathol. 8 (2015), 4715–4724.
    • (2015) Int. J. Clin. Exp. Pathol. , vol.8 , pp. 4715-4724
    • Wang, C.1    Fei, Y.2    Xu, C.3    Zhao, Y.4    Pan, Y.5
  • 177
    • 84927647671 scopus 로고    scopus 로고
    • Galectin-1-secreting neural stem cells elicit long-term neuroprotection against ischemic brain injury
    • Wang, J., Xia, J., Zhang, F., Shi, Y., Wu, Y., Pu, H., Liou, A.K., Leak, R.K., Yu, X., Chen, L., Chen, J., Galectin-1-secreting neural stem cells elicit long-term neuroprotection against ischemic brain injury. Sci. Rep., 5, 2015, 9621.
    • (2015) Sci. Rep. , vol.5 , pp. 9621
    • Wang, J.1    Xia, J.2    Zhang, F.3    Shi, Y.4    Wu, Y.5    Pu, H.6    Liou, A.K.7    Leak, R.K.8    Yu, X.9    Chen, L.10    Chen, J.11
  • 178
    • 84959137932 scopus 로고    scopus 로고
    • Advances in adipose-derived stem cells isolation, characterization, and application in regenerative tissue engineering
    • Wankhade, U.D., Shen, M., Kolhe, R., Fulzele, S., Advances in adipose-derived stem cells isolation, characterization, and application in regenerative tissue engineering. Stem Cells Int., 2016, 2016, 3206807.
    • (2016) Stem Cells Int. , vol.2016 , pp. 3206807
    • Wankhade, U.D.1    Shen, M.2    Kolhe, R.3    Fulzele, S.4
  • 179
    • 84877709953 scopus 로고    scopus 로고
    • Delayed intranasal delivery of hypoxic-preconditioned bone marrow mesenchymal stem cells enhanced cell homing and therapeutic benefits after ischemic stroke in mice
    • Wei, N., Yu, S.P., Gu, X., Taylor, T.M., Song, D., Liu, X.F., Wei, L., Delayed intranasal delivery of hypoxic-preconditioned bone marrow mesenchymal stem cells enhanced cell homing and therapeutic benefits after ischemic stroke in mice. Cell Transplant. 22 (2013), 977–991.
    • (2013) Cell Transplant. , vol.22 , pp. 977-991
    • Wei, N.1    Yu, S.P.2    Gu, X.3    Taylor, T.M.4    Song, D.5    Liu, X.F.6    Wei, L.7
  • 181
    • 15544383394 scopus 로고    scopus 로고
    • Embryonic stem cells: prospects for developmental biology and cell therapy
    • Wobus, A.M., Boheler, K.R., Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol. Rev. 85 (2005), 635–678.
    • (2005) Physiol. Rev. , vol.85 , pp. 635-678
    • Wobus, A.M.1    Boheler, K.R.2
  • 184
    • 84876667774 scopus 로고    scopus 로고
    • Comparison of the neural differentiation potential of human mesenchymal stem cells from amniotic fluid and adult bone marrow
    • Yan, Z.J., Hu, Y.Q., Zhang, H.T., Zhang, P., Xiao, Z.Y., Sun, X.L., Cai, Y.Q., Hu, C.C., Xu, R.X., Comparison of the neural differentiation potential of human mesenchymal stem cells from amniotic fluid and adult bone marrow. Cell. Mol. Neurobiol. 33 (2013), 465–475.
    • (2013) Cell. Mol. Neurobiol. , vol.33 , pp. 465-475
    • Yan, Z.J.1    Hu, Y.Q.2    Zhang, H.T.3    Zhang, P.4    Xiao, Z.Y.5    Sun, X.L.6    Cai, Y.Q.7    Hu, C.C.8    Xu, R.X.9
  • 185
    • 79954436506 scopus 로고    scopus 로고
    • Human umbilical cord-derived Schwann-like cell transplantation combined with neurotrophin-3 administration in dyskinesia of rats with spinal cord injury
    • Yan-Wu, G., Yi-Quan, K., Ming, L., Ying-Qian, C., Xiao-Dan, J., Shi-Zhong, Z., Wang-Ming, Z., Chuan-Zhi, D., Human umbilical cord-derived Schwann-like cell transplantation combined with neurotrophin-3 administration in dyskinesia of rats with spinal cord injury. Neurochem. Res. 36 (2011), 783–792.
    • (2011) Neurochem. Res. , vol.36 , pp. 783-792
    • Yan-Wu, G.1    Yi-Quan, K.2    Ming, L.3    Ying-Qian, C.4    Xiao-Dan, J.5    Shi-Zhong, Z.6    Wang-Ming, Z.7    Chuan-Zhi, D.8
  • 187
    • 84865299284 scopus 로고    scopus 로고
    • Enriched environment and white matter in aging brain
    • Yang, S., Lu, W., Zhou, D.S., Tang, Y., Enriched environment and white matter in aging brain. Anat. Rec. (Hoboken) 295 (2012), 1406–1414.
    • (2012) Anat. Rec. (Hoboken) , vol.295 , pp. 1406-1414
    • Yang, S.1    Lu, W.2    Zhou, D.S.3    Tang, Y.4
  • 188
    • 84889245910 scopus 로고    scopus 로고
    • Intra-arterial delivery is not superior to intravenous delivery of autologous bone marrow mononuclear cells in acute ischemic stroke
    • Yang, B., Migliati, E., Parsha, K., Schaar, K., Xi, X., Aronowski, J., Savitz, S.I., Intra-arterial delivery is not superior to intravenous delivery of autologous bone marrow mononuclear cells in acute ischemic stroke. Stroke 44 (2013), 3463–3472.
    • (2013) Stroke , vol.44 , pp. 3463-3472
    • Yang, B.1    Migliati, E.2    Parsha, K.3    Schaar, K.4    Xi, X.5    Aronowski, J.6    Savitz, S.I.7
  • 189
    • 33947127571 scopus 로고    scopus 로고
    • Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease
    • Ye, M., Wang, X.J., Zhang, Y.H., Lu, G.Q., Liang, L., Xu, J.Y., Chen, S.D., Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease. Brain Res. 1142 (2007), 206–216.
    • (2007) Brain Res. , vol.1142 , pp. 206-216
    • Ye, M.1    Wang, X.J.2    Zhang, Y.H.3    Lu, G.Q.4    Liang, L.5    Xu, J.Y.6    Chen, S.D.7
  • 191
    • 84870469486 scopus 로고    scopus 로고
    • Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease
    • Yin, F., Tian, Z.M., Liu, S., Zhao, Q.J., Wang, R.M., Shen, L., Wieman, J., Yan, Y., Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease. CNS Neurosci. Ther. 18 (2012), 1012–1020.
    • (2012) CNS Neurosci. Ther. , vol.18 , pp. 1012-1020
    • Yin, F.1    Tian, Z.M.2    Liu, S.3    Zhao, Q.J.4    Wang, R.M.5    Shen, L.6    Wieman, J.7    Yan, Y.8
  • 192
    • 84878895614 scopus 로고    scopus 로고
    • Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery occlusion
    • Yuan, T., Liao, W., Feng, N.H., Lou, Y.L., Niu, X., Zhang, A.J., Wang, Y., Deng, Z.F., Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery occlusion. Stem Cell Res. Ther., 4, 2013, 73.
    • (2013) Stem Cell Res. Ther. , vol.4 , pp. 73
    • Yuan, T.1    Liao, W.2    Feng, N.H.3    Lou, Y.L.4    Niu, X.5    Zhang, A.J.6    Wang, Y.7    Deng, Z.F.8
  • 193
    • 84911007828 scopus 로고    scopus 로고
    • Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer's disease
    • Zhang, W., Wang, P.J., Sha, H.Y., Ni, J., Li, M.H., Gu, G.J., Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer's disease. Mol. Neurobiol. 50 (2014), 423–437.
    • (2014) Mol. Neurobiol. , vol.50 , pp. 423-437
    • Zhang, W.1    Wang, P.J.2    Sha, H.Y.3    Ni, J.4    Li, M.H.5    Gu, G.J.6
  • 194
    • 84875714090 scopus 로고    scopus 로고
    • Recovery of behavioral symptoms in hemi-parkinsonian rhesus monkeys through combined gene and stem cell therapy
    • Zhou, Y., Sun, M., Li, H., Yan, M., He, Z., Wang, W., Wang, W., Lu, S., Recovery of behavioral symptoms in hemi-parkinsonian rhesus monkeys through combined gene and stem cell therapy. Cytotherapy 15 (2013), 467–480.
    • (2013) Cytotherapy , vol.15 , pp. 467-480
    • Zhou, Y.1    Sun, M.2    Li, H.3    Yan, M.4    He, Z.5    Wang, W.6    Wang, W.7    Lu, S.8
  • 195
    • 84928138738 scopus 로고    scopus 로고
    • Human umbilical cord-derived mesenchymal stem cells improve learning and memory function in hypoxic-ischemic brain-damaged rats via an IL-8-mediated secretion mechanism rather than differentiation pattern induction
    • Zhou, X., Gu, J., Gu, Y., He, M., Bi, Y., Chen, J., Li, T., Human umbilical cord-derived mesenchymal stem cells improve learning and memory function in hypoxic-ischemic brain-damaged rats via an IL-8-mediated secretion mechanism rather than differentiation pattern induction. Cell. Physiol. Biochem. 35 (2015), 2383–2401.
    • (2015) Cell. Physiol. Biochem. , vol.35 , pp. 2383-2401
    • Zhou, X.1    Gu, J.2    Gu, Y.3    He, M.4    Bi, Y.5    Chen, J.6    Li, T.7
  • 196
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic, B.V., Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat. Rev. Neurosci. 12 (2011), 723–738.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 197
    • 84900453177 scopus 로고    scopus 로고
    • Induced pluripotent stem (iPS) cells: a new source for cell-based therapeutics
    • de Lazaro, I., Yilmazer, A., Kostarelos, K., Induced pluripotent stem (iPS) cells: a new source for cell-based therapeutics. J. Control. Release 185 (2014), 37–44.
    • (2014) J. Control. Release , vol.185 , pp. 37-44
    • de Lazaro, I.1    Yilmazer, A.2    Kostarelos, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.