Human umbilical cord-derived mesenchymal stem cells improve learning and memory function in hypoxic-ischemic brain-damaged rats via an IL-8-mediated secretion mechanism rather than differentiation pattern induction

Cellular Physiology and Biochemistry

Volumn 35, Issue 6, 2015, Pages 2383-2401

  Zhou, Xiaoqin ^a   Gu, Jialu ^a   Gu, Yan ^a   He, Mulan ^a   Bi, Yang ^a   Chen, Jie ^a   Li, Tingyu ^a  

^a CHILDREN S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Differentiation; Human umbilical cord derived mesenchymal stem cells; Hypoxic ischemic brain damage; IL 8; Learning memory function

Indexed keywords

BETA TUBULIN; BETA1 INTEGRIN; ENDOGLIN; HERMES ANTIGEN; HLA ANTIGEN; INTERLEUKIN 8; STRESS ACTIVATED PROTEIN KINASE; THY 1 ANTIGEN; BIOLOGICAL MARKER;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CELLULAR SECRETION; CHROMOSOME ABERRATION; CHROMOSOME STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VIVO STUDY; LATENT PERIOD; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; METAPHASE; MORRIS WATER MAZE TEST; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPATIAL LEARNING; SPATIAL MEMORY; THERAPY EFFECT; UMBILICAL CORD DERIVED MESENCHYMAL STEM CELL; ANIMAL; CELL CULTURE; LEARNING; MEMORY; MESENCHYMAL STROMA CELL; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; UMBILICAL CORD;

RATTUS;

ANIMALS; BIOMARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; HIPPOCAMPUS; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; INTERLEUKIN-8; LEARNING; MEMORY; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; NEOVASCULARIZATION, PATHOLOGIC; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; UMBILICAL CORD;

EID: 84928138738     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000374040     Document Type: Article

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