Dissociative increase of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia

Neuroscience Letters

Volumn 335, Issue 3, 2003, Pages 159-162

  Ohta, Kentaro ^a   Iwai, Masanori ^a   Sato, Keiko ^a   Omori, Nobuhiko ^a   Nagano, Isao ^a   Shoji, Mikio ^a   Abe, Koji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Aging; Brain infarction; Neuron glial antigen 2 (NG2); Oligodendrocyte progenitor cell; Remyelination; Transient ischemia

Indexed keywords

PROTEOCHONDROITIN SULFATE;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL PROLIFERATION; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; REPERFUSION; STEM CELL;

AGING; ANIMALS; ANTIGENS; BRAIN ISCHEMIA; FLUORESCENT ANTIBODY TECHNIQUE; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MITOSIS; OLIGODENDROGLIA; PROTEOGLYCANS; RATS; RATS, WISTAR; STEM CELLS; TIME FACTORS;

EID: 0037413659     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)01177-1     Document Type: Article

References (21)

1. Abe K. Therapeutic potential of neurotrophic factors and neural stem cells against ischemic brain injury. J. Cereb. Blood Flow Metab. 20:2000;1393-1408.
2. Abe K., Aoki M., Kawagoe J., Yoshida T., Hattori A., Kogure K., Itoyama Y. Ischemic delayed neuronal death: a mitochondrial hypothesis. Stroke. 26:1995;1478-1489.
3. Abe K., Kogure K. Selective gene expression after brain ischemia. Prog. Brain Res. 96:1993;221-236.
4. Abe K., Tanzi R.E., Kogure K. Mechanism of arachidonic acid liberation during ischemia in gerbil cerebral cortex. J. Neurochem. 48:1987;503-509.
5. Abe K., Tanzi R.E., Kogure K. Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex. Neurosci. Lett. 125:1991;172-174.
6. Chang A., Nishiyama A., Peterson J., Prineas J., Trapp B.D. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J. Neurosci. 20:2000;6404-6412.
7. Chang A., Touretellotte W.W., Rudick R., Trapp B.D. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N. Engl. J. Med. 346:2002;165-173.
8. Fok-Seang J., Mathews G.A., ffrench-Constant C., Trotter J., Fawcett J.W. Migration of oligodendrocyte precursors on astrocytes and meningeal cells. Dev. Biol. 171:1995;1-15.
9. Hoyer S. Ischemia in aged brain. Gerontology. 33:1987;203-206.
10. Kitagawa H., Sasaki C., Sakai K., Mori A., Mitsumoto Y., Mori T., Fukuchi Y., Abe K. Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents ischemic brain injury after transient middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. 19:1999;1336-1344.
11. Kondo T., Raff M. Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science. 289:2000;1754-1757.
12. Levine J.M. Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury. J. Neurosci. 14:1994;4716-4730.
13. Levine J.M., Reynolds R., Fawcett J.W. The oligodendrocyte precursor cell in health and disease. Trends Neurosci. 24:2001;39-47.
14. Levine J.M., Stincone F., Lee Y.S. Development and differentiation of glial precursor cells in the rat cerebellum. Glia. 7:1993;307-321.
15. Litten L., Raff M. Differentiation signals in the CNS: Type-2 astrocyte development in vitro as a model system. Neuron. 5:1990;111-119.
16. Nishiyama A., Yu M., Drazba J.A., Vincent K.T. Normal and reactive NG2+glial cells are distinct from resting and activated microglia. J. Neurosci. Res. 48:1997;299-321.
17. Ong W.Y., Levine J.M. A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus. Neuroscience. 92:1999;83-95.
18. Sasaki C., Hayashi T., Zhang W.R., Warita H., Manabe Y., Sakai K., Abe K. Different effect of glycogen synthase kinase-3β between young and old rat brain after transient middle cerebral artery occlusion. Neurol. Res. 23:2001;588-592.
19. Tanaka K., Nogawa S., Ito D., Suzuki S., Dembo T., Kosakai A., Fukuuchi Y. Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain. NeuroReport. 12:2001;2169-2174.
20. Wang G.X., Li G.R., Wang Y.D., Yang T.S., Ouyang Y.B. Characterization of neuronal cell death in normal and diabetic rats following experimental focal cerebral ischemia. Life Sciences. 69:2001;2801-2810.
21. Yagita Y., Kitagawa K., Ohtsuki T., Takasawa K., Miyata T., Okano H., Hori M., Matsumoto M. Neurogenesis by progenitor cells in the ischemic adult rat hippocampus. Stroke. 32:2001;1890-1896.