-
1
-
-
0021237993
-
Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man
-
Küpfer, A. and Preisig, R.: Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man. Eur. J. Clin. Pharmacol., 26: 753-759 (1984).
-
(1984)
Eur. J. Clin. Pharmacol.
, vol.26
, pp. 753-759
-
-
Küpfer, A.1
Preisig, R.2
-
2
-
-
0017695082
-
Polymorphic hydroxylation of debrisoquine in man
-
Mahgoub, A., Idle, J. R., Dring, L. G. and Lancaster, R.: Polymorphic hydroxylation of debrisoquine in man. Lancet, 17: 584-586 (1977).
-
(1977)
Lancet
, vol.17
, pp. 584-586
-
-
Mahgoub, A.1
Idle, J.R.2
Dring, L.G.3
Lancaster, R.4
-
3
-
-
0018615011
-
Defective N-oxidation of sparteine in man: A new pharmacogenetic defect
-
Eichelbaum, M., Spannbrucker, N., Steincke, B. and Dengler, H. J.: Defective N-oxidation of sparteine in man: A new pharmacogenetic defect. Eur. J. Clin. Pharmacol., 16: 183-187 (1979).
-
(1979)
Eur. J. Clin. Pharmacol.
, vol.16
, pp. 183-187
-
-
Eichelbaum, M.1
Spannbrucker, N.2
Steincke, B.3
Dengler, H.J.4
-
4
-
-
0022337949
-
Extremely rapid hydroxylation of debrisoquine: A case report with implication for treatment with nortriptyline and other tricyclic antidepressants
-
Bertilsson, L., Åberg-Wistedt, A., Gustafsson, L. L. and Nordin, C.: Extremely rapid hydroxylation of debrisoquine: A case report with implication for treatment with nortriptyline and other tricyclic antidepressants. Ther. Drug Monit., 7: 478-480 (1985).
-
(1985)
Ther. Drug Monit.
, vol.7
, pp. 478-480
-
-
Bertilsson, L.1
Åberg-Wistedt, A.2
Gustafsson, L.L.3
Nordin, C.4
-
5
-
-
0034894010
-
CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages
-
Kirchheiner, J., Brøsen, K., Dahl, M. L., Gram, L. F., Kasper, S., Roots, I., Sjoqvist, F., Spina, E. and Brockmoller, J.: CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages. Acta. Psychiatr. Scand., 104: 173-192 (2001).
-
(2001)
Acta. Psychiatr. Scand.
, vol.104
, pp. 173-192
-
-
Kirchheiner, J.1
Brøsen, K.2
Dahl, M.L.3
Gram, L.F.4
Kasper, S.5
Roots, I.6
Sjoqvist, F.7
Spina, E.8
Brockmoller, J.9
-
6
-
-
0036561590
-
Genetic polymorphism of drug metabolizing enzymes
-
Fujieda, M., Yamazaki, H. and Kamataki, T.: Genetic polymorphism of drug metabolizing enzymes. Jpn. J. Cancer Chemother., 29(5): 663-668 (2002).
-
(2002)
Jpn. J. Cancer Chemother.
, vol.29
, pp. 663-668
-
-
Fujieda, M.1
Yamazaki, H.2
Kamataki, T.3
-
7
-
-
0036357709
-
Genetic polymorphisms in drug-metabolizing enzymes
-
Saruwatari, T., Nakagawa K. and Ishizaki, T.: Genetic polymorphisms in drug-metabolizing enzymes. Nippon Rinsho, 60: 58-63 (2002).
-
(2002)
Nippon Rinsho
, vol.60
, pp. 58-63
-
-
Saruwatari, T.1
Nakagawa, K.2
Ishizaki, T.3
-
8
-
-
0033929925
-
Pharmacogenetics and psychopharmacotherapy
-
Poolsup, N., Po, A. L. W. and Knight, T. L.: Pharmacogenetics and psychopharmacotherapy. J. Clin. Pharm. Ther., 25: 197-220 (2000).
-
(2000)
J. Clin. Pharm. Ther.
, vol.25
, pp. 197-220
-
-
Poolsup, N.1
Po, A.L.W.2
Knight, T.L.3
-
9
-
-
0032793249
-
Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment
-
Ingelman-sundberg, M., Oscarson, M. and McLellan, R. A.: Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. Trends Pharmacol. Sci., 20: 342-349 (1999).
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 342-349
-
-
Ingelman-sundberg, M.1
Oscarson, M.2
McLellan, R.A.3
-
10
-
-
0035028479
-
Molecular basis of ethnic differences in drug disposition and response
-
Xie, H.-G., Kim, R. B., Wood, A. J. J. and Stein, C. M.: Molecular basis of ethnic differences in drug disposition and response. Annu. Rev. Pharmacol. Toxicol., 41: 815-850 (2001).
-
(2001)
Annu. Rev. Pharmacol. Toxicol.
, vol.41
, pp. 815-850
-
-
Xie, H.-G.1
Kim, R.B.2
Wood, A.J.J.3
Stein, C.M.4
-
11
-
-
0024796958
-
The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene
-
Kimura, S., Umeno, M., Skoda, R. C., Meyer, U. A. and Gonzalez, F. J.: The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. Am. J. Hum. Genet., 45: 889-904 (1989).
-
(1989)
Am. J. Hum. Genet.
, vol.45
, pp. 889-904
-
-
Kimura, S.1
Umeno, M.2
Skoda, R.C.3
Meyer, U.A.4
Gonzalez, F.J.5
-
12
-
-
0033821139
-
CYP2D6 genotypes in a Japanese population: low frequencies of CYP2D6 gene duplication but high frequency of CYP2D6*10
-
Nishida, Y., Fukuda, T., Yamamoto, I. and Azuma, J.: CYP2D6 genotypes in a Japanese population: low frequencies of CYP2D6 gene duplication but high frequency of CYP2D6*10. Pharmacogenetics, 10: 567-570 (2000).
-
(2000)
Pharmacogenetics
, vol.10
, pp. 567-570
-
-
Nishida, Y.1
Fukuda, T.2
Yamamoto, I.3
Azuma, J.4
-
13
-
-
0029053644
-
Genetic analysis of the CYP2D6 locus in relation to debrisoquine hydroxylation capacity in Korean, Japanese and Chinese subjects
-
Dahl, M.-L., Yue, Q.-Y., Roh, H.-K., Johasson, I., Sawe, J., Sjoqvist, F. and Bertilsson, J.: Genetic analysis of the CYP2D6 locus in relation to debrisoquine hydroxylation capacity in Korean, Japanese and Chinese subjects. Pharmacogenetics, 5: 159-164 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 159-164
-
-
Dahl, M.-L.1
Yue, Q.-Y.2
Roh, H.-K.3
Johasson, I.4
Sawe, J.5
Sjoqvist, F.6
Bertilsson, J.7
-
14
-
-
0032586732
-
Analysis of the CYP2D6 gene in relation to dextromethorphan O-demethylation capacity in a Japanese population
-
Tateishi, T., Chida, M., Ariyoshi, N., Mizorogi, Y., Kamataki, T. and Kobayashi, S.: Analysis of the CYP2D6 gene in relation to dextromethorphan O-demethylation capacity in a Japanese population. Clin. Pharmacol. Ther., 65: 570-575 (1999).
-
(1999)
Clin. Pharmacol. Ther.
, vol.65
, pp. 570-575
-
-
Tateishi, T.1
Chida, M.2
Ariyoshi, N.3
Mizorogi, Y.4
Kamataki, T.5
Kobayashi, S.6
-
15
-
-
85024460148
-
-
Setou, K., Ieiri, I., Fujii, K., Higuchi, S., Kimura, M., Urae, A., Irie, S. and Ohtsubo, K.: Jpn. J. Clin. Pharmacol. Ther., 30: 79-80 (1999).
-
(1999)
Jpn. J. Clin. Pharmacol. Ther.
, vol.30
, pp. 79-80
-
-
Setou, K.1
Ieiri, I.2
Fujii, K.3
Higuchi, S.4
Kimura, M.5
Urae, A.6
Irie, S.7
Ohtsubo, K.8
-
16
-
-
0027965620
-
Genetic analysis of the Chinese cytochrome P4502D locus. Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation
-
Johansson, I., Oscarson, M., Yue, Q.-Y., Bertilsson, L., Sjöqvist, F. and Ingelman-Sundberg, M.: Genetic analysis of the Chinese cytochrome P4502D locus. Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation. Mol. Pharmacol., 46: 452-459 (1994).
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 452-459
-
-
Johansson, I.1
Oscarson, M.2
Yue, Q.-Y.3
Bertilsson, L.4
Sjöqvist, F.5
Ingelman-Sundberg, M.6
-
17
-
-
0034094251
-
Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes
-
Kubota, T., Yamaura, Y., Ohkawa, N., Hara, H. and Chiba, K.: Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes. Br. J. Clin. Pharmacol., 50: 31-34 (2000).
-
(2000)
Br. J. Clin. Pharmacol.
, vol.50
, pp. 31-34
-
-
Kubota, T.1
Yamaura, Y.2
Ohkawa, N.3
Hara, H.4
Chiba, K.5
-
18
-
-
0034948852
-
Heterogeneity of the CYP2D6 gene among Malays in Malaysia
-
Teh, L. K., Ismail, R., Yusoff, R., Hussein, A., Isa, M. N. and Rahman, A. R. A.: Heterogeneity of the CYP2D6 gene among Malays in Malaysia. J. Clin. Pharm. Ther., 26: 205-211 (2001).
-
(2001)
J. Clin. Pharm. Ther.
, vol.26
, pp. 205-211
-
-
Teh, L.K.1
Ismail, R.2
Yusoff, R.3
Hussein, A.4
Isa, M.N.5
Rahman, A.R.A.6
-
19
-
-
0031828554
-
Comparison of three CYP2D6 probe substrates and genotype in Ghanaians, Chinese and Caucasians
-
Droll, K., Brouce-Mensah, K., Otton, S. V., Gaedigk, A., Sellers, E. M. and Tyndale, R. F.: Comparison of three CYP2D6 probe substrates and genotype in Ghanaians, Chinese and Caucasians. Pharmacogenetics, 8: 325-333 (1998).
-
(1998)
Pharmacogenetics
, vol.8
, pp. 325-333
-
-
Droll, K.1
Brouce-Mensah, K.2
Otton, S.V.3
Gaedigk, A.4
Sellers, E.M.5
Tyndale, R.F.6
-
20
-
-
0032505437
-
Association between the debrisoquine hydroxylase gene polymorphism and the genetic susceptibility of Parkinson's disease
-
Tao, E., Liu, Z., Chen, B., Pan, X. and Shao, M.: Association between the debrisoquine hydroxylase gene polymorphism and the genetic susceptibility of Parkinson's disease. Chin. J. Med. Genet., 15: 281-283 (1998).
-
(1998)
Chin. J. Med. Genet.
, vol.15
, pp. 281-283
-
-
Tao, E.1
Liu, Z.2
Chen, B.3
Pan, X.4
Shao, M.5
-
21
-
-
0031946127
-
Rarity of debrisoquine hydroxylase gene polymorphism in Chinese patients with Parkinson's disease
-
Pang, C. P., Zhang, J., Woo, J., Chan, D., Law, L. K., Tong, S. F., Kwok, T. and Kay, R.: Rarity of debrisoquine hydroxylase gene polymorphism in Chinese patients with Parkinson's disease. Mov. Disord., 13: 529-532 (1998).
-
(1998)
Mov. Disord.
, vol.13
, pp. 529-532
-
-
Pang, C.P.1
Zhang, J.2
Woo, J.3
Chan, D.4
Law, L.K.5
Tong, S.F.6
Kwok, T.7
Kay, R.8
-
22
-
-
0032585361
-
Mutation analysis of CYP2D6 locus in the Korean population: identification of rare poor metabolizer alleles at the nucleotide level
-
Ryu, S.-W., Kim, Y.-J. and Kim, E.: Mutation analysis of CYP2D6 locus in the Korean population: identification of rare poor metabolizer alleles at the nucleotide level. Mol. Cells, 8: 758-763 (1998).
-
(1998)
Mol. Cells
, vol.8
, pp. 758-763
-
-
Ryu, S.-W.1
Kim, Y.-J.2
Kim, E.3
-
23
-
-
0034756617
-
Genetic polymorphism of CYP2D6: Malaysian indians have the highest frequency for CYP2D6*4 in Asia
-
Ismail, R. and Teh, L. K.: Genetic polymorphism of CYP2D6: Malaysian indians have the highest frequency for CYP2D6*4 in Asia. Eur. J. Clin. Pharmacol., 57: 617-618 (2001).
-
(2001)
Eur. J. Clin. Pharmacol.
, vol.57
, pp. 617-618
-
-
Ismail, R.1
Teh, L.K.2
-
24
-
-
0028028050
-
Debrisoquine and mephenytoin oxidation in Sinhalese a population study
-
Weerasuriya, K., Jayakody, R. L., Smith, C. A. D., Wolf, C. R., Tucker, G. T. and Lennard, M. S. Debrisoquine and mephenytoin oxidation in Sinhalese a population study. Br. J. Clin. Pharmacol., 38 466-470 (1994).
-
(1994)
Br. J. Clin. Pharmacol.
, vol.38
, pp. 466-470
-
-
Weerasuriya, K.1
Jayakody, R.L.2
Smith, C.A.D.3
Wolf, C.R.4
Tucker, G.T.5
Lennard, M.S.6
-
25
-
-
0029817869
-
ApoE and CYP2D6 polymorphism with and without parkinsonism-dementia complex in the people of Chamorro, Guam
-
Chen, X., Xia, Y., Gresham, L. S., Molgaard, C. A., Thomas, R. G., Galasko, D., Wiederholt, W. C. and Saitoh, T.: ApoE and CYP2D6 polymorphism with and without parkinsonism-dementia complex in the people of Chamorro, Guam. Neurology, 47: 779-784 (1996).
-
(1996)
Neurology
, vol.47
, pp. 779-784
-
-
Chen, X.1
Xia, Y.2
Gresham, L.S.3
Molgaard, C.A.4
Thomas, R.G.5
Galasko, D.6
Wiederholt, W.C.7
Saitoh, T.8
-
26
-
-
0034815333
-
Polymorphisms at CYP and GST gene loci
-
Buch, S., Kotekar, A., Kawle, D. and Bhisey, R.: Polymorphisms at CYP and GST gene loci. Eur. J. Clin. Pharmacol., 57: 553-555 (2001).
-
(2001)
Eur. J. Clin. Pharmacol.
, vol.57
, pp. 553-555
-
-
Buch, S.1
Kotekar, A.2
Kawle, D.3
Bhisey, R.4
-
27
-
-
0027418152
-
Molecular basis of genetic variation in debrisoquine hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6
-
Wang, S.-L., Huang, J., Lai, M.-D., Liu, B.-H. and Lai, M.-L.: Molecular basis of genetic variation in debrisoquine hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6. Clin. Pharmacol. Ther., 53: 410-418 (1993).
-
(1993)
Clin. Pharmacol. Ther.
, vol.53
, pp. 410-418
-
-
Wang, S.-L.1
Huang, J.2
Lai, M.-D.3
Liu, B.-H.4
Lai, M.-L.5
-
28
-
-
0028182215
-
Frequency of human CYP2D6 mutant alleles in a normal Chinese population
-
Lee, E. J. D. and Jeyaseelan, K.: Frequency of human CYP2D6 mutant alleles in a normal Chinese population. Br. J. Clin. Pharmacol., 37: 605-607 (1994).
-
(1994)
Br. J. Clin. Pharmacol.
, vol.37
, pp. 605-607
-
-
Lee, E.J.D.1
Jeyaseelan, K.2
-
29
-
-
0029824252
-
Debrisoquine and S-mephenytoin hydroxylation phenotypes and genotypes in a Korean population
-
Roh, H. K., Dahl, M. L., Johansson, I., Ingelman-Sundberg, M., Cha, Y. N. and Bertilsson, L.: Debrisoquine and S-mephenytoin hydroxylation phenotypes and genotypes in a Korean population. Pharmacogenetics, 6: 441-447 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 441-447
-
-
Roh, H.K.1
Dahl, M.L.2
Johansson, I.3
Ingelman-Sundberg, M.4
Cha, Y.N.5
Bertilsson, L.6
-
30
-
-
0033934317
-
Correlation of genetic polymorphism of cytochrome P4502D6 with dextromethorphan oxidative metabolism in Chinese
-
Cai, W., Chen, B., Tao, X., Ling, S. and Zhang, Y.: Correlation of genetic polymorphism of cytochrome P4502D6 with dextromethorphan oxidative metabolism in Chinese. Chin. J. Med. Genet., 17: 181-184 (2000).
-
(2000)
Chin. J. Med. Genet.
, vol.17
, pp. 181-184
-
-
Cai, W.1
Chen, B.2
Tao, X.3
Ling, S.4
Zhang, Y.5
-
31
-
-
0032963135
-
G169R mutation diminishes the metabolic activity of CYP2D6 in Chinese
-
Wang, S. L., Lai, M.-D. and Huang, J.-D.: G169R mutation diminishes the metabolic activity of CYP2D6 in Chinese. Drug Metab. Dispos., 27: 385-388 (1999).
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 385-388
-
-
Wang, S.L.1
Lai, M.-D.2
Huang, J.-D.3
-
32
-
-
10344266435
-
A new CYP2D6 allele with a nine base insertion in exon 9 in a Japanese population associated with poor metabolizer phenotype
-
Yokoi, T., Kosaka, Y., Chiba, M., Nakamura, H., Ishizaki, T., Kinoshita, M., Sato, K., Gonzalez, F. J. and Kamataki, T.: A new CYP2D6 allele with a nine base insertion in exon 9 in a Japanese population associated with poor metabolizer phenotype. Pharmacogenetics, 6: 395-401 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 395-401
-
-
Yokoi, T.1
Kosaka, Y.2
Chiba, M.3
Nakamura, H.4
Ishizaki, T.5
Kinoshita, M.6
Sato, K.7
Gonzalez, F.J.8
Kamataki, T.9
-
33
-
-
0032525742
-
Linkage of mutant allele of CYP2C18 and CYP2C19 in a Japanese population
-
Kubota, T., Hibi, N. and Chiba, K.: Linkage of mutant allele of CYP2C18 and CYP2C19 in a Japanese population. Biochem. Pharmacol., 55: 2039-2042 (1998).
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 2039-2042
-
-
Kubota, T.1
Hibi, N.2
Chiba, K.3
-
34
-
-
0030580125
-
Genotype analysis of the CYP2C19 gene in the Japanese population
-
Tsuneoka, Y., Fukushima, K., Matsuo, Y., Ichikawa, Y. and Watanabe, Y.: Genotype analysis of the CYP2C19 gene in the Japanese population. Life Sci., 59: 1711-1715 (1996).
-
(1996)
Life Sci.
, vol.59
, pp. 1711-1715
-
-
Tsuneoka, Y.1
Fukushima, K.2
Matsuo, Y.3
Ichikawa, Y.4
Watanabe, Y.5
-
35
-
-
0030473384
-
CYP2C19 genotype and phenotype determined by omeprazole in a Korean population
-
Roh, H.-K., Dahl, M.-L., Tybring, G., Yamada, H., Cha, Y.-N. and Bertilsson, L.: CYP2C19 genotype and phenotype determined by omeprazole in a Korean population. Pharmacogenetics, 6: 547-551 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 547-551
-
-
Roh, H.-K.1
Dahl, M.-L.2
Tybring, G.3
Yamada, H.4
Cha, Y.-N.5
Bertilsson, L.6
-
36
-
-
0032995228
-
A rapid and simple detection of genetic defects responsible for the phenotypic polymorphism of cytochrome P450 2C19
-
Itoh, K., Inoue, K., Yanagawa, S., Kyoya, H. and Suzuki, T.: A rapid and simple detection of genetic defects responsible for the phenotypic polymorphism of cytochrome P450 2C19. Biol. Pharm. Bull., 22: 77-79 (1999).
-
(1999)
Biol. Pharm. Bull.
, vol.22
, pp. 77-79
-
-
Itoh, K.1
Inoue, K.2
Yanagawa, S.3
Kyoya, H.4
Suzuki, T.5
-
37
-
-
0029994586
-
Evidence that poor metabolizers of (S)-mephenytoin could be identified by haplotypes of CYP2C19 in Japanese
-
Takakubo, F., Kuwano, A. and Kondo, I.: Evidence that poor metabolizers of (S)-mephenytoin could be identified by haplotypes of CYP2C19 in Japanese. Pharmacogenetics, 6: 265-267 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 265-267
-
-
Takakubo, F.1
Kuwano, A.2
Kondo, I.3
-
38
-
-
0031840217
-
Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population
-
Kimura, M., Ieiri, I., Mamiya, K., Urae, A. and Higuchi, S.: Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population. Ther. Drug Monit., 20: 243-247 (1998).
-
(1998)
Ther. Drug Monit.
, vol.20
, pp. 243-247
-
-
Kimura, M.1
Ieiri, I.2
Mamiya, K.3
Urae, A.4
Higuchi, S.5
-
39
-
-
0035111438
-
Phenotype analysis of cytochrome P450 2C19 in Chinese subjects with mephenytoin S/R enantiomeric ratio in urine measured by chiral GC
-
Yao, T. W., Zeng, S., Wang, T. W. and Chen, W. Q.: Phenotype analysis of cytochrome P450 2C19 in Chinese subjects with mephenytoin S/R enantiomeric ratio in urine measured by chiral GC. Biomed. Chromatogr., 15: 9-13 (2001).
-
(2001)
Biomed. Chromatogr.
, vol.15
, pp. 9-13
-
-
Yao, T.W.1
Zeng, S.2
Wang, T.W.3
Chen, W.Q.4
-
40
-
-
33748957565
-
The incidence of genetic polymorphisms of CYP 2C in a Korean population
-
Ko, J.-W., Macpherson, A. S., Jang, I.-J., Shin, S.-G. and Flochart, D. A.: The incidence of genetic polymorphisms of CYP 2C in a Korean population. Clin. Pharmacol. Ther., 61: 226 (1997).
-
(1997)
Clin. Pharmacol. Ther.
, vol.61
, pp. 226
-
-
Ko, J.-W.1
Macpherson, A.S.2
Jang, I.-J.3
Shin, S.-G.4
Flochart, D.A.5
-
41
-
-
0031714780
-
Canadian Native Indians exhibit unique CYP2A6 and CYP2C19 mutant allele frequencies
-
Nowak, M. P., Sellers, E. M. and Tyndale, R. F.: Canadian Native Indians exhibit unique CYP2A6 and CYP2C19 mutant allele frequencies. Clin. Pharmacol. Ther., 64: 378-383 (1998).
-
(1998)
Clin. Pharmacol. Ther.
, vol.64
, pp. 378-383
-
-
Nowak, M.P.1
Sellers, E.M.2
Tyndale, R.F.3
-
42
-
-
8244249473
-
Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele
-
Xiao, Z.-S., Goldstein, J. A., Xie, H.-G., Blaidell, J., Wang, W., Jiang, C.-H., Yan, F.-X., He, N., Huang, S.-L., Xu, Z.-H. and Zhou, H.-H.: Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele. J. Pharmacol. Exp. Ther., 281: 604-609 (1997).
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 604-609
-
-
Xiao, Z.-S.1
Goldstein, J.A.2
Xie, H.-G.3
Blaidell, J.4
Wang, W.5
Jiang, C.-H.6
Yan, F.-X.7
He, N.8
Huang, S.-L.9
Xu, Z.-H.10
Zhou, H.-H.11
-
43
-
-
0030904031
-
Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian an American black populations
-
Goldstein, J. A., Ishizaki, T., Chiba, K., de Morais, S. M. F., Bell, D., Krahn, P. M. and Evans, A. P.: Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian an American black populations. Pharmacogenetics, 7: 59-64 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 59-64
-
-
Goldstein, J.A.1
Ishizaki, T.2
Chiba, K.3
de Morais, S.M.F.4
Bell, D.5
Krahn, P.M.6
Evans, A.P.7
-
44
-
-
0034896764
-
Identification of N-acetyltransferase 2 and CYP2C19 genotypes for hair, buccal cell swabs, or fingernails compared with blood
-
Tanigawara, Y., Kita, T., Hirono, M., Sakaeda, T., Komada, F. and Okumura, K.: Identification of N-acetyltransferase 2 and CYP2C19 genotypes for hair, buccal cell swabs, or fingernails compared with blood. Ther. Drug Monit., 23: 341-346 (2001).
-
(2001)
Ther. Drug Monit.
, vol.23
, pp. 341-346
-
-
Tanigawara, Y.1
Kita, T.2
Hirono, M.3
Sakaeda, T.4
Komada, F.5
Okumura, K.6
-
45
-
-
0030444707
-
Genotyping of S-mephenytoin 4'-hydroxylation in an extended Japanese population
-
Kubota, T., Chiba, K. and Ishizaki, T.: Genotyping of S-mephenytoin 4'-hydroxylation in an extended Japanese population. Clin. Pharmacol. Ther., 60: 661-666 (1996).
-
(1996)
Clin. Pharmacol. Ther.
, vol.60
, pp. 661-666
-
-
Kubota, T.1
Chiba, K.2
Ishizaki, T.3
-
46
-
-
0031884233
-
Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population
-
Griese, E.-U., Zanger, U.M., Brudermanns, U., Gaedigk, A., Mikus, G., Mdrike, K., Stiiven, T. and Eichelbaum, M.: Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population. Pharmacogenetics, 8: 15-26 (1998).
-
(1998)
Pharmacogenetics
, vol.8
, pp. 15-26
-
-
Griese, E.-U.1
Zanger, U.M.2
Brudermanns, U.3
Gaedigk, A.4
Mikus, G.5
Mdrike, K.6
Stiiven, T.7
Eichelbaum, M.8
-
47
-
-
0030692086
-
Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease
-
Bandmann, O., Vaughan, J., Holmans, P., Marsden, C. D. and Wood, N. W.: Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease. Lancet, 350: 1136-1139 (1997).
-
(1997)
Lancet
, vol.350
, pp. 1136-1139
-
-
Bandmann, O.1
Vaughan, J.2
Holmans, P.3
Marsden, C.D.4
Wood, N.W.5
-
48
-
-
0030481307
-
Increased risk for hepatocellular carcinoma in NAT2-slow acetylators and CYP2D6-rapid metabolizer
-
Agilndez, J. A. G., Olivera, M., Ladero, J. M., Rodriguez-Lescure, A., Ledesma, M. C., Diaz-Rubio, M., Meyer, U. A. and Benitez, J.: Increased risk for hepatocellular carcinoma in NAT2-slow acetylators and CYP2D6-rapid metabolizer. Pharmacogenetics, 6: 501-512 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 501-512
-
-
Agilndez, J.A.G.1
Olivera, M.2
Ladero, J.M.3
Rodriguez-Lescure, A.4
Ledesma, M.C.5
Diaz-Rubio, M.6
Meyer, U.A.7
Benitez, J.8
-
49
-
-
0034891594
-
Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-American in Southern California
-
Wan, Y.-J.Y., Poland, R. E., Han, G., Konishi, T., Zheng, Y.-P., Berman, N. and Lin, K.-M.: Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-American in Southern California. Pharmacogenetics, 11: 489-499 (2001).
-
(2001)
Pharmacogenetics
, vol.11
, pp. 489-499
-
-
Wan, Y.-J.Y.1
Poland, R.E.2
Han, G.3
Konishi, T.4
Zheng, Y.-P.5
Berman, N.6
Lin, K.-M.7
-
50
-
-
0033461165
-
Optimization of cytochrome P4502D6 (CYP2Dphenotype assignment using a genotyping algorithm based on allele frequency data
-
Gaedigk, A., Gotschall, R. R., Forbes, N. S., Simon, S. D., Kearns, G. L. and Leeder J. S.: Optimization of cytochrome P4502D6 (CYP2Dphenotype assignment using a genotyping algorithm based on allele frequency data. Pharmacogenetics, 9: 669-682 (1999).
-
(1999)
Pharmacogenetics
, vol.9
, pp. 669-682
-
-
Gaedigk, A.1
Gotschall, R.R.2
Forbes, N.S.3
Simon, S.D.4
Kearns, G.L.5
Leeder, J.S.6
-
51
-
-
0035011225
-
Pharmacogenetic profile of xenobiotic enzyme metabolism in survivors of the Spanish toxic oil syndrome
-
Ladona, M. G., Izquierdo-Martinez, M., Posada de la Paz, M., De la Torre, R., Ampurdanes, C., Segura, J. and Sanz, E. J.: Pharmacogenetic profile of xenobiotic enzyme metabolism in survivors of the Spanish toxic oil syndrome. Environ. Health Perspect., 109: 369-375 (2001).
-
(2001)
Environ. Health Perspect.
, vol.109
, pp. 369-375
-
-
Ladona, M.G.1
Izquierdo-Martinez, M.2
Posada de la Paz, M.3
De la Torre, R.4
Ampurdanes, C.5
Segura, J.6
Sanz, E.J.7
-
52
-
-
0032421471
-
CYP2D6 phenotype-genotype relationships in African-Americans and Caucasians in Los Angeles
-
Leathart, J. B. J., London, S. J., Steward, A., Adams, J. D., Idle, J. R. and Daly, A. K.: CYP2D6 phenotype-genotype relationships in African-Americans and Caucasians in Los Angeles. Pharmacogenetics, 8: 529-541 (1998).
-
(1998)
Pharmacogenetics
, vol.8
, pp. 529-541
-
-
Leathart, J.B.J.1
London, S.J.2
Steward, A.3
Adams, J.D.4
Idle, J.R.5
Daly, A.K.6
-
53
-
-
17844400295
-
Functionally active duplications of the CYP2D6 gene are more prevalent among larynx and lung cancer patients
-
Agilndez, J. A. G., Gallardo, L., Ledesma, M. C., Lozano, L., Rodriguez-Lescure, A., Pontes, J. C., Iglesias-Moreno, M. C., Poch, J., Ladero, J. M. and Benitez, J.: Functionally active duplications of the CYP2D6 gene are more prevalent among larynx and lung cancer patients. Oncology, 61: 59-63 (2001).
-
(2001)
Oncology
, vol.61
, pp. 59-63
-
-
Agilndez, J.A.G.1
Gallardo, L.2
Ledesma, M.C.3
Lozano, L.4
Rodriguez-Lescure, A.5
Pontes, J.C.6
Iglesias-Moreno, M.C.7
Poch, J.8
Ladero, J.M.9
Benitez, J.10
-
54
-
-
0032865809
-
CYP2D6 mutations and therapeutic outcome in schizophrenic patients
-
Hamelin, B. A., Dorson, P. G., Pabos, D., Still, D., Bouchard, R.-H., Pourcher, E., Rail, J., Turgeon, J. and Crismon, M. L.: CYP2D6 mutations and therapeutic outcome in schizophrenic patients. Pharmacotherapy, 19: 1057-1063 (1999).
-
(1999)
Pharmacotherapy
, vol.19
, pp. 1057-1063
-
-
Hamelin, B.A.1
Dorson, P.G.2
Pabos, D.3
Still, D.4
Bouchard, R.-H.5
Pourcher, E.6
Rail, J.7
Turgeon, J.8
Crismon, M.L.9
-
55
-
-
0030765119
-
Genetically deficient CYP2D6 metabolism provides protection against oral opiate dependence
-
Tyndale, R. F., Droll, K. P. and Sellers, E. M.: Genetically deficient CYP2D6 metabolism provides protection against oral opiate dependence. Pharmacogenetics, 7: 375-379 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 375-379
-
-
Tyndale, R.F.1
Droll, K.P.2
Sellers, E.M.3
-
56
-
-
0031445496
-
Debrisoquine and S-mephenytoin hydroxylation polymorphisms in a Russian population living in Estonia
-
Marandi, T., Dahl, M. L., Rägo, L., Kiivet, R. and Sjoqvist, F.: Debrisoquine and S-mephenytoin hydroxylation polymorphisms in a Russian population living in Estonia. Eur. J. Clin. Pharmacol., 53: 257-260 (1997).
-
(1997)
Eur. J. Clin. Pharmacol.
, vol.53
, pp. 257-260
-
-
Marandi, T.1
Dahl, M.L.2
Rägo, L.3
Kiivet, R.4
Sjoqvist, F.5
-
57
-
-
0033871198
-
Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR
-
Hersberger, M., Marti-Jaun, J., Rentsch, K. and Hänseler, E.: Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR. Clin. Chem., 46: 1072-1077 (2000).
-
(2000)
Clin. Chem.
, vol.46
, pp. 1072-1077
-
-
Hersberger, M.1
Marti-Jaun, J.2
Rentsch, K.3
Hänseler, E.4
-
58
-
-
0030217818
-
Brief Communication CYP2D6 genotyping in a Russian population using a novel approach for identification of the CYP2D6A mutation
-
Akhmedova, S. N., Pushnova, E. A., Anisimov, S., Bogdanova, L. A., Bova, K. L. and Schwarts, E. I.: Brief Communication CYP2D6 genotyping in a Russian population using a novel approach for identification of the CYP2D6A mutation. Biochem. Mol. Med., 58: 234-236 (1996).
-
(1996)
Biochem. Mol. Med.
, vol.58
, pp. 234-236
-
-
Akhmedova, S.N.1
Pushnova, E.A.2
Anisimov, S.3
Bogdanova, L.A.4
Bova, K.L.5
Schwarts, E.I.6
-
59
-
-
0026670643
-
Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers
-
Graf, T., Broly, F., Hoffmann, F., Probst, M., Meyer, U. A. and Howald, H.: Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers. Eur. J. Clin. Pharmacol., 43: 399-403 (1992).
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.43
, pp. 399-403
-
-
Graf, T.1
Broly, F.2
Hoffmann, F.3
Probst, M.4
Meyer, U.A.5
Howald, H.6
-
60
-
-
0026747176
-
Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease
-
Smith, C. A. D., Gough, A. C., Leigh, P. N., Summers, B. A., Harding, A. E., Maranganore, D. M., Sturman, S. G., Schapira, A. H. V., Williams, A. C., Spurr, N. K. and Wolf, D. R.: Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease. Lancet, 339: 1375-1377 (1992).
-
(1992)
Lancet
, vol.339
, pp. 1375-1377
-
-
Smith, C.A.D.1
Gough, A.C.2
Leigh, P.N.3
Summers, B.A.4
Harding, A.E.5
Maranganore, D.M.6
Sturman, S.G.7
Schapira, A.H.V.8
Williams, A.C.9
Spurr, N.K.10
Wolf, D.R.11
-
61
-
-
0028174586
-
Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls
-
Terfe, T., Daly, A. K., Armstrong, M., Leathart, J. B. S., Idle, J. R., Brøgger, A. and Borresen, A.-L.: Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls. Pharmacogenetics, 4: 47-57 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 47-57
-
-
Terfe, T.1
Daly, A.K.2
Armstrong, M.3
Leathart, J.B.S.4
Idle, J.R.5
Brøgger, A.6
Borresen, A.-L.7
-
62
-
-
0034052291
-
Cytochrome P450 2D6 and glutathione S-transferase M1genotypes and migraine
-
Mattsson, P., Bjelfman, C., Lundberg, P. O. and Rane, A.: Cytochrome P450 2D6 and glutathione S-transferase M1genotypes and migraine. Eur. J. Clin. Invest., 30: 367-371 (2000).
-
(2000)
Eur. J. Clin. Invest.
, vol.30
, pp. 367-371
-
-
Mattsson, P.1
Bjelfman, C.2
Lundberg, P.O.3
Rane, A.4
-
63
-
-
0031682185
-
CYP2D6 and CYP2C19 genotypes in an elderly Swedish population
-
Yamada, H., Dahl, M.-L., Lannfelt, L., Viitanen, M., Winblad, B. and Sjöqvist, F.: CYP2D6 and CYP2C19 genotypes in an elderly Swedish population. Eur. J. Clin. Pharmacol., 54: 479-481 (1998).
-
(1998)
Eur. J. Clin. Pharmacol.
, vol.54
, pp. 479-481
-
-
Yamada, H.1
Dahl, M.-L.2
Lannfelt, L.3
Viitanen, M.4
Winblad, B.5
Sjöqvist, F.6
-
64
-
-
0027457052
-
PCR-based CYP2D6 genotyping for Finnish lung cancer patients
-
Hirvonen, A., Husgafvel-Pursiainen, K., Anttila, S., Karjalainen, A., Pelkonen, O. and Vainio H.: PCR-based CYP2D6 genotyping for Finnish lung cancer patients. Pharmacogenetics, 3: 19-27 (1993).
-
(1993)
Pharmacogenetics
, vol.3
, pp. 19-27
-
-
Hirvonen, A.1
Husgafvel-Pursiainen, K.2
Anttila, S.3
Karjalainen, A.4
Pelkonen, O.5
Vainio, H.6
-
65
-
-
0032911172
-
Study of the association between cytochromes P450 2D6 and 2E1 genotypes and the risk of drug and chemical induced idiosyncratic aplastic anaemia
-
Marsh, J. C., Chowdry, J., Parry-Jones, N., Ellis, S. W., Muir, K. R., Gordon-Smith, E. C. and Tucker, G. T.: Study of the association between cytochromes P450 2D6 and 2E1 genotypes and the risk of drug and chemical induced idiosyncratic aplastic anaemia. Br. J. Haematol., 104: 266-270 (1999).
-
(1999)
Br. J. Haematol.
, vol.104
, pp. 266-270
-
-
Marsh, J.C.1
Chowdry, J.2
Parry-Jones, N.3
Ellis, S.W.4
Muir, K.R.5
Gordon-Smith, E.C.6
Tucker, G.T.7
-
66
-
-
0033790667
-
Poor metabolizers at the cytochrome P450 2D6 and 2C19 loci are at increased risk of developing adult acute leukaemia
-
Roddam, P. L., Rollinson, S., Kane, E., Roman, E., Moorman, A., Cartwright, R. and Morgan, G. J.: Poor metabolizers at the cytochrome P450 2D6 and 2C19 loci are at increased risk of developing adult acute leukaemia. Pharmacogenetics, 10: 605-615 (2000).
-
(2000)
Pharmacogenetics
, vol.10
, pp. 605-615
-
-
Roddam, P.L.1
Rollinson, S.2
Kane, E.3
Roman, E.4
Moorman, A.5
Cartwright, R.6
Morgan, G.J.7
-
67
-
-
0033230795
-
Rapid detection of CYP1A1, CYP2D6, and NAT variants by multiplex polymerase chain reaction and allele-specific oligonucleotide assay
-
Labuda, D., Krajinovic, M., Richer, C., Skoll, A., Sinnett, H., Yotavo, V. and Sinnett, D.: Rapid detection of CYP1A1, CYP2D6, and NAT variants by multiplex polymerase chain reaction and allele-specific oligonucleotide assay. Anal. Biochem., 275: 84-92 (1999).
-
(1999)
Anal. Biochem.
, vol.275
, pp. 84-92
-
-
Labuda, D.1
Krajinovic, M.2
Richer, C.3
Skoll, A.4
Sinnett, H.5
Yotavo, V.6
Sinnett, D.7
-
68
-
-
0030576157
-
Letter to the Editor Lack of association between schizophrenia and the CYP2D6 gene polymorphisms
-
(Neuropsychiatric Genetics)
-
Pirmohamed, M., Wild, M. J., Kitteringham, N. R., O'Brien, K., Buchan, I. E., Back, D. J. and Park, B. K.: Letter to the Editor Lack of association between schizophrenia and the CYP2D6 gene polymorphisms. Am. J. Med. Genet. (Neuropsychiatric Genetics), 67: 236-237 (1996).
-
(1996)
Am. J. Med. Genet.
, vol.67
, pp. 236-237
-
-
Pirmohamed, M.1
Wild, M.J.2
Kitteringham, N.R.3
O'Brien, K.4
Buchan, I.E.5
Back, D.J.6
Park, B.K.7
-
69
-
-
0030030519
-
Relationship between genotype for the cytochrome P450 CYP2D6 and susceptibility to ankylosing spondylitis and rheumatoid arthritis
-
Beyler, C., Armstrong, M., Bird, H. A., Idle, J. R. and Daly, A. K.: Relationship between genotype for the cytochrome P450 CYP2D6 and susceptibility to ankylosing spondylitis and rheumatoid arthritis. Ann. Rheum. Dis., 55: 66-68 (1996).
-
(1996)
Ann. Rheum. Dis.
, vol.55
, pp. 66-68
-
-
Beyler, C.1
Armstrong, M.2
Bird, H.A.3
Idle, J.R.4
Daly, A.K.5
-
70
-
-
0028596610
-
An association study of debrisoquine hydroxylase (CYP2Dpolymorphisms in schizophrenia
-
Dawson, E., Powell, J. F., Nöthen, M. M., Crocq, M.-A., Lanczik, M., Körner, J., Rietschel, M., van Os, J., Wright, P. and Gill, M.: An association study of debrisoquine hydroxylase (CYP2Dpolymorphisms in schizophrenia. Psychiatr. Genet., 4: 215-218 (1994).
-
(1994)
Psychiatr. Genet.
, vol.4
, pp. 215-218
-
-
Dawson, E.1
Powell, J.F.2
Nöthen, M.M.3
Crocq, M.-A.4
Lanczik, M.5
Körner, J.6
Rietschel, M.7
van Os, J.8
Wright, P.9
Gill, M.10
-
71
-
-
0028947973
-
No association between schizopherenia and polymorphisms within the genes for debrisoquine 4-hydoxylase (CYP2Dand the dopamine transporter (DAT)
-
(Neuropsychiatric Genetics)
-
Daniels, J., Williams, J., Asherson, P., McGuffin, P. and Owen, M.: No association between schizopherenia and polymorphisms within the genes for debrisoquine 4-hydoxylase (CYP2Dand the dopamine transporter (DAT). Am. J. Med. Genet. (Neuropsychiatric Genetics), 60: 85-87 (1995).
-
(1995)
Am. J. Med. Genet.
, vol.60
, pp. 85-87
-
-
Daniels, J.1
Williams, J.2
Asherson, P.3
McGuffin, P.4
Owen, M.5
-
72
-
-
0032718495
-
Ten percent of North Spanish individuals carry duplicated or triplicated CYP2D6 genes associated with ultrarapid metabolism of debrisoquine
-
Bernal, M. L., Sinues, B., Johansson, I., McLellan, R. A., Wennerholm, A., Dahl, M.-L., Ingelman-Sundberg, M. and Bertilsson, L.: Ten percent of North Spanish individuals carry duplicated or triplicated CYP2D6 genes associated with ultrarapid metabolism of debrisoquine. Pharmacogenetics, 9: 657-660 (1999).
-
(1999)
Pharmacogenetics
, vol.9
, pp. 657-660
-
-
Bernal, M.L.1
Sinues, B.2
Johansson, I.3
McLellan, R.A.4
Wennerholm, A.5
Dahl, M.-L.6
Ingelman-Sundberg, M.7
Bertilsson, L.8
-
73
-
-
0033532119
-
Neurogenetic correlates of Parkinson's disease: apolipoprotein-E and cytochrome P450 2D6 genetic polymorphism
-
Bon, M. A. M., Steur, E.N.H.J., de Vos, R. A. I. and Vermes, I.: Neurogenetic correlates of Parkinson's disease: apolipoprotein-E and cytochrome P450 2D6 genetic polymorphism. Neurosci. Lett., 266: 149-151 (1999).
-
(1999)
Neurosci. Lett.
, vol.266
, pp. 149-151
-
-
Bon, M.A.M.1
Steur, E.N.H.J.2
de Vos, R.A.I.3
Vermes, I.4
-
74
-
-
0002656419
-
Analysis of the CYP2D6 and 2C19 genotype in large African-American (AA) and Caucasian (C) populations
-
Martin, D. E., Tran, J. Q., Flockhart, D. A. and Jorkasky, D. K.: Analysis of the CYP2D6 and 2C19 genotype in large African-American (AA) and Caucasian (C) populations. Clin. Pharmacol. Ther., 63: 206 (1998).
-
(1998)
Clin. Pharmacol. Ther.
, vol.63
, pp. 206
-
-
Martin, D.E.1
Tran, J.Q.2
Flockhart, D.A.3
Jorkasky, D.K.4
-
75
-
-
0029150871
-
Prediction of phenotype for dextromethorphan O-demethylation by using polymerase chain reaction in healthy volunteers
-
Zimmermann, T., Schlenk, R., Pfaff, G., Lach, P. and Wildfeuer, A.: Prediction of phenotype for dextromethorphan O-demethylation by using polymerase chain reaction in healthy volunteers. Drug Res., 45: 41-43 (1995).
-
(1995)
Drug Res.
, vol.45
, pp. 41-43
-
-
Zimmermann, T.1
Schlenk, R.2
Pfaff, G.3
Lach, P.4
Wildfeuer, A.5
-
76
-
-
0344780903
-
Candidate genetic modifiers of individual susceptibility to renal cell carcinoma: a study of polymorphic human xenobiotic-metabolizing enzymes
-
Longuemaux, S., Deloménie, C., Gallou, C., Méjean, A., Vincent-Viry, M., Bouvier, R., Droz, D., Krishnamoorthy, R., Galteau, M.-M., Junien, C., Beroud, C. and Dupret, J.-M.: Candidate genetic modifiers of individual susceptibility to renal cell carcinoma: a study of polymorphic human xenobiotic-metabolizing enzymes. Cancer Res., 59: 2903-2908 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 2903-2908
-
-
Longuemaux, S.1
Deloménie, C.2
Gallou, C.3
Méjean, A.4
Vincent-Viry, M.5
Bouvier, R.6
Droz, D.7
Krishnamoorthy, R.8
Galteau, M.-M.9
Junien, C.10
Beroud, C.11
Dupret, J.-M.12
-
77
-
-
0031799019
-
Lack of association between human longevity and genetic polymorphisms in drug-metabolizing enzymes at the NAT2, GSTM1 and CYP2D6 loci
-
Muiras, M.-L., Verasdonck, P., Cottet, F. and Schachter, F.: Lack of association between human longevity and genetic polymorphisms in drug-metabolizing enzymes at the NAT2, GSTM1 and CYP2D6 loci. Hum. Genet., 102: 526-532 (1998).
-
(1998)
Hum. Genet.
, vol.102
, pp. 526-532
-
-
Muiras, M.-L.1
Verasdonck, P.2
Cottet, F.3
Schachter, F.4
-
78
-
-
0029846366
-
Mutation frequencies of the cytochrome CYP2D6 gene in Parkinson disease patients and in families
-
Neuropsychiatric Genetics)
-
Lucotte, G., Turpin, J.-C., Gérard, N., Panserat, S. and Krishnamoorthy, R.: Mutation frequencies of the cytochrome CYP2D6 gene in Parkinson disease patients and in families. Am. J. Med. Genet. (Neuropsychiatric Genetics), 67: 361-365 (1996).
-
(1996)
Am. J. Med. Genet.
, vol.67
, pp. 361-365
-
-
Lucotte, G.1
Turpin, J.-C.2
Gérard, N.3
Panserat, S.4
Krishnamoorthy, R.5
-
79
-
-
0029876756
-
Lack of relation between genetic polymorphism of cytochrome P-450IID6 and sporadic idiopathic Parkinson's disease
-
Bordet, R., Broly, F., Destée, A., Libersa, C. and Lafitte, J. J.: Lack of relation between genetic polymorphism of cytochrome P-450IID6 and sporadic idiopathic Parkinson's disease. Clin. Neurophar-macol., 19: 213-221 (1996).
-
(1996)
Clin. Neurophar-macol.
, vol.19
, pp. 213-221
-
-
Bordet, R.1
Broly, F.2
Destée, A.3
Libersa, C.4
Lafitte, J.J.5
-
80
-
-
0035297113
-
CYP2D6 polymorphism in Parkinson's disease: The Rotterdam study
-
Harhangi, B. S., Oostra, B. A., Heutink, P., van Duijn, C. M., Hofman, A. and Breteker, M. M. B.: CYP2D6 polymorphism in Parkinson's disease: The Rotterdam study. Mov. Disord., 16: 290-293 (2001).
-
(2001)
Mov. Disord.
, vol.16
, pp. 290-293
-
-
Harhangi, B.S.1
Oostra, B.A.2
Heutink, P.3
van Duijn, C.M.4
Hofman, A.5
Breteker, M.M.B.6
-
81
-
-
0028969436
-
Imipra-mine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms a population study
-
Madsen, H., Nielsen, K. K. and Brøsen, K.: Imipra-mine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms a population study. Br. J. Clin. Pharmacol., 39: 433-439 (1995).
-
(1995)
Br. J. Clin. Pharmacol.
, vol.39
, pp. 433-439
-
-
Madsen, H.1
Nielsen, K.K.2
Brøsen, K.3
-
82
-
-
0029895951
-
Debrisoquin and S-mephenytoin hydroxylation phenotypes and CYP2D6 genotypes in an Estonian population
-
Marandi, T., Dahl, M. L., Kiivet, R. A., Rägo, L. and Sj÷qvist, F.: Debrisoquin and S-mephenytoin hydroxylation phenotypes and CYP2D6 genotypes in an Estonian population. Pharmacol. Toxicol., 78: 303-307 (1996).
-
(1996)
Pharmacol. Toxicol.
, vol.78
, pp. 303-307
-
-
Marandi, T.1
Dahl, M.L.2
Kiivet, R.A.3
Rägo, L.4
Sj÷qvist, F.5
-
83
-
-
0033734942
-
Genotyping of CYP2D6 in Parkinson's disease
-
Štefanović, M., Topić, E., Ivaniěvić, A.-M., Relji, M. and Korĭć, M.: Genotyping of CYP2D6 in Parkinson's disease. Clin. Chem. Lab. Med., 38: 929-934 (2000).
-
(2000)
Clin. Chem. Lab. Med.
, vol.38
, pp. 929-934
-
-
Štefanović, M.1
Topić, E.2
Ivaniěvić, A.-M.3
Relji, M.4
Korĭć, M.5
-
84
-
-
0028829818
-
Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls
-
Dolžan, V., Rudolf, Z. and Breskvar, K.: Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls. Carcinogenesis, 16: 2675-2678 (1995).
-
(1995)
Carcinogenesis
, vol.16
, pp. 2675-2678
-
-
Dolžan, V.1
Rudolf, Z.2
Breskvar, K.3
-
85
-
-
0032839303
-
CYP2D6 and GSTM1 genotypes in a Polish population
-
Gawrońska-Szklaz, B., Wójcicki, M., Kuprianowicz, A., Kedzierska, K., Kedzierski, M., Górnik, W. and Pawlik, A.: CYP2D6 and GSTM1 genotypes in a Polish population. Eur. J. Clin. Pharmacol., 55: 389-392 (1999).
-
(1999)
Eur. J. Clin. Pharmacol.
, vol.55
, pp. 389-392
-
-
Gawrońska-Szklaz, B.1
Wójcicki, M.2
Kuprianowicz, A.3
Kedzierska, K.4
Kedzierski, M.5
Górnik, W.6
Pawlik, A.7
-
86
-
-
0034114171
-
Development and characterization of a rapid and comprehensive genotyping assay to detect the most common variants in cytochrome P450 2D6
-
Scarlett, L. A., Madani, S., Shen, D. D. and Ho, R. J. Y.: Development and characterization of a rapid and comprehensive genotyping assay to detect the most common variants in cytochrome P450 2D6. Pharm. Res., 17: 242-246 (2000).
-
(2000)
Pharm. Res.
, vol.17
, pp. 242-246
-
-
Scarlett, L.A.1
Madani, S.2
Shen, D.D.3
Ho, R.J.Y.4
-
87
-
-
0030056697
-
CYP2D6 allelic frequencies in young-onset Parkinson's disease
-
Sandy, M. S., Armstrong, M., Tanner, C. M., Daly, A. K., Monte, D. A., Langston, J. W. and Idle, J. R.: CYP2D6 allelic frequencies in young-onset Parkinson's disease. Neurology, 47: 225-230 (1996).
-
(1996)
Neurology
, vol.47
, pp. 225-230
-
-
Sandy, M.S.1
Armstrong, M.2
Tanner, C.M.3
Daly, A.K.4
Monte, D.A.5
Langston, J.W.6
Idle, J.R.7
-
88
-
-
0031472072
-
The association between polymorphisms in the cytochrome P-450 2D6 gene and Parkinson's disease: a case-control study and meta-analysis
-
McCann, S. J., Pond, S. M., James, S. M. and Le Couteur, D. G.: The association between polymorphisms in the cytochrome P-450 2D6 gene and Parkinson's disease: a case-control study and meta-analysis. J. Neurol. Sci., 153: 50-53 (1997).
-
(1997)
J. Neurol. Sci.
, vol.153
, pp. 50-53
-
-
McCann, S.J.1
Pond, S.M.2
James, S.M.3
Le Couteur, D.G.4
-
89
-
-
0032248612
-
Genetic polymorphism of CYP1A1 and CYP2D6 in the Tundra Nentsi population of Siberia
-
Lyakhovich, V. V., Mitrofanov, D. V., Gutkina, N. I., Duzhak, T. G., Posukh, O. L. and Osipova, L. P.: Genetic polymorphism of CYP1A1 and CYP2D6 in the Tundra Nentsi population of Siberia. Int. J. Circumpo-lar Health, 57: 725-729 (1998).
-
(1998)
Int. J. Circumpo-lar Health
, vol.57
, pp. 725-729
-
-
Lyakhovich, V.V.1
Mitrofanov, D.V.2
Gutkina, N.I.3
Duzhak, T.G.4
Posukh, O.L.5
Osipova, L.P.6
-
90
-
-
0035719119
-
Metabolic genotypes and risk for colorectal cancer
-
Butler, W. J., Ryan, P. and Roberts-Thomson, I. C.: Metabolic genotypes and risk for colorectal cancer. J. Gastroenterol. Hepatol., 16: 631-635 (2001).
-
(2001)
J. Gastroenterol. Hepatol.
, vol.16
, pp. 631-635
-
-
Butler, W.J.1
Ryan, P.2
Roberts-Thomson, I.C.3
-
91
-
-
0029851872
-
The CYP2D6B allele is not overrepresented in a population of German patients with idiopathic Parkinson's disease
-
Gasser, T., Müller-Myhsok, B., Supala, A., Zimmer,E., Wieditz, G., Wszolek, Z. K., Vieregge, P. Bonafati, V. and Oertel, W. H.: The CYP2D6B allele is not overrepresented in a population of German patients with idiopathic Parkinson's disease. J. Neurol. Neurosurg. Psychiatry, 61: 518-520 (1996).
-
(1996)
J. Neurol. Neurosurg. Psychiatry
, vol.61
, pp. 518-520
-
-
Gasser, T.1
Müller-Myhsok, B.2
Supala, A.3
Zimmer, E.4
Wieditz, G.5
Wszolek, Z.K.6
Vieregge, P.7
Bonafati, V.8
Oertel, W.H.9
-
92
-
-
0027054926
-
Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility
-
Smith, C. A. D., Moss, J. E., Gough, A. C., Spurr, N. K. and Wolf, C. R.: Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility. Environ. Health Perspect., 98: 107-112 (1992).
-
(1992)
Environ. Health Perspect.
, vol.98
, pp. 107-112
-
-
Smith, C.A.D.1
Moss, J.E.2
Gough, A.C.3
Spurr, N.K.4
Wolf, C.R.5
-
93
-
-
0032811583
-
Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias
-
Lemos, M. C., Carbrita, F. J., Silva, H. A., Vinvan, M., Placido, F. and Regateiro, F. J.: Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias. Carcinogenesis, 20: 1225-1229 (1999).
-
(1999)
Carcinogenesis
, vol.20
, pp. 1225-1229
-
-
Lemos, M.C.1
Carbrita, F.J.2
Silva, H.A.3
Vinvan, M.4
Placido, F.5
Regateiro, F.J.6
-
94
-
-
0031843052
-
Genetic polymorphism of N-acetyltransferase-2, glutathione S-transferase-M1, and cytochromes P450IIE1 and P450IID6 in the susceptibility to head and neck cancer
-
González, M. V., Alvarez, V., Pello, M. F., Menendez, M. J., Suarez, C. and Coto, E.: Genetic polymorphism of N-acetyltransferase-2, glutathione S-transferase-M1, and cytochromes P450IIE1 and P450IID6 in the susceptibility to head and neck cancer. J. Clin. Pathol., 51: 294-298 (1998).
-
(1998)
J. Clin. Pathol.
, vol.51
, pp. 294-298
-
-
González, M.V.1
Alvarez, V.2
Pello, M.F.3
Menendez, M.J.4
Suarez, C.5
Coto, E.6
-
95
-
-
0032879511
-
Genetic polymorphisms influence variability in benzene metabolism in humans
-
Rossi, A. M., Guarnieri, C., Rovesti, S., Gobba, F., Ghittori, S., Vivoli, G. and Barale, R.: Genetic polymorphisms influence variability in benzene metabolism in humans. Pharmacogenetics, 9: 445-451 (1999).
-
(1999)
Pharmacogenetics
, vol.9
, pp. 445-451
-
-
Rossi, A.M.1
Guarnieri, C.2
Rovesti, S.3
Gobba, F.4
Ghittori, S.5
Vivoli, G.6
Barale, R.7
-
96
-
-
26744449964
-
Genetic evidence of differences in Parkinson's disease susceptibility by CYP2D6 and MAOB genotypes
-
Kurth, M. C., Kurth, J. H., Hubble, J. P., Sliger, L., Eggers, B., Lieberman, A. N. and Koller, W. C.: Genetic evidence of differences in Parkinson's disease susceptibility by CYP2D6 and MAOB genotypes. Am. J. Hum. Genet., 57SS: 1964 (1995).
-
(1964)
Am. J. Hum. Genet.
, vol.57SS
-
-
Kurth, M.C.1
Kurth, J.H.2
Hubble, J.P.3
Sliger, L.4
Eggers, B.5
Lieberman, A.N.6
Koller, W.C.7
-
97
-
-
0028929652
-
An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution
-
Daly, A. K., Leathart, J. B. S., London, S. J. and Idle, J. R.: An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution. Hum. Genet., 95: 337-341 (1995).
-
(1995)
Hum. Genet.
, vol.95
, pp. 337-341
-
-
Daly, A.K.1
Leathart, J.B.S.2
London, S.J.3
Idle, J.R.4
-
98
-
-
0028305240
-
Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype
-
Saxena, R., Shaw, G. L., Relling, M. V., Frame, J. N., Moir, D. T., Evans, W. E. and Caporaso, B. W.: Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype. Hum. Mol. Genet., 3: 923-926 (1994).
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 923-926
-
-
Saxena, R.1
Shaw, G.L.2
Relling, M.V.3
Frame, J.N.4
Moir, D.T.5
Evans, W.E.6
Caporaso, B.W.7
-
99
-
-
0028806579
-
A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency
-
Broly, F., Marez, D., Lo Guidice, J.-M., Sabbagh, N., Legrand, M., Boone, P. and Meyer, U. A.: A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency. Hum. Genet., 96: 601-603 (1995).
-
(1995)
Hum. Genet.
, vol.96
, pp. 601-603
-
-
Broly, F.1
Marez, D.2
Lo Guidice, J.-M.3
Sabbagh, N.4
Legrand, M.5
Boone, P.6
Meyer, U.A.7
-
100
-
-
0028826569
-
A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype
-
Marez, D., Sabbagh, N., Legrand, M., Lo-Guidice, P. and Broly, F.: A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype. Pharmacogenetics, 5: 305-311 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 305-311
-
-
Marez, D.1
Sabbagh, N.2
Legrand, M.3
Lo-Guidice, P.4
Broly, F.5
-
101
-
-
0029937877
-
An additional allelic variant of CYP2D6 gene causing impaired metabolism of sparteine
-
Marez, D., Legrand, M., Sabbagh, N., Lo-Guidice, J. M., Boone, P. and Broly, F.: An additional allelic variant of CYP2D6 gene causing impaired metabolism of sparteine. Hum. Genet., 97: 668-670 (1996).
-
(1996)
Hum. Genet.
, vol.97
, pp. 668-670
-
-
Marez, D.1
Legrand, M.2
Sabbagh, N.3
Lo-Guidice, J.M.4
Boone, P.5
Broly, F.6
-
102
-
-
0031858351
-
Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevity Role of CYP2D6 and CYP2C19 in longevity
-
Bathum, L., Andersen-Ranberg, K., Boldsen, J., Brosen, K. and Jeune, B.: Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevity Role of CYP2D6 and CYP2C19 in longevity. Eur. J. Clin. Pharmacol., 54: 427-430 (1998).
-
(1998)
Eur. J. Clin. Pharmacol.
, vol.54
, pp. 427-430
-
-
Bathum, L.1
Andersen-Ranberg, K.2
Boldsen, J.3
Brosen, K.4
Jeune, B.5
-
103
-
-
0012887670
-
Allele frequency of CYP2C19 in a Portuguese population
-
Ruas, J. L. and Lechner, M. C.: Allele frequency of CYP2C19 in a Portuguese population. Pharmacogenetics, 7: 333-335 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 333-335
-
-
Ruas, J.L.1
Lechner, M.C.2
-
104
-
-
0031787036
-
Relationship between proguanil metabolic ratio and CYP2C19 genotype in a Caucasian population
-
Hoskins, J. M., Shenfield, G. M. and Gross, A. S.: Relationship between proguanil metabolic ratio and CYP2C19 genotype in a Caucasian population. Br. J. Clin. Pharmacol., 46: 499-504 (1998).
-
(1998)
Br. J. Clin. Pharmacol.
, vol.46
, pp. 499-504
-
-
Hoskins, J.M.1
Shenfield, G.M.2
Gross, A.S.3
-
105
-
-
0032772078
-
Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population
-
Aynacioglu, A. S., Sachse, C., Bozkurt, A., Kortunay, S., Nacak, M., Schroder, T., Kayaalp, S. O., Roots, I. and Brockmoller, J.: Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population. Clin. Pharmacol. Ther., 66: 185-192 (1999).
-
(1999)
Clin. Pharmacol. Ther.
, vol.66
, pp. 185-192
-
-
Aynacioglu, A.S.1
Sachse, C.2
Bozkurt, A.3
Kortunay, S.4
Nacak, M.5
Schroder, T.6
Kayaalp, S.O.7
Roots, I.8
Brockmoller, J.9
-
106
-
-
0034743396
-
Characterization of the CYP2D6*29 allele commonly present in a black Tanzanian population causing reduced catalytic activity
-
Wennerholm, A., Johansson, I., Hidestrand, M., Bertilsson, L., Gustafsson, L.L. and Ingelman-Sundberg, M.: Characterization of the CYP2D6*29 allele commonly present in a black Tanzanian population causing reduced catalytic activity. Pharmacogenetics, 11: 417-427 (2001).
-
(2001)
Pharmacogenetics
, vol.11
, pp. 417-427
-
-
Wennerholm, A.1
Johansson, I.2
Hidestrand, M.3
Bertilsson, L.4
Gustafsson, L.L.5
Ingelman-Sundberg, M.6
-
107
-
-
0035039209
-
Genetic polymorphism of CYP2D6 and CYP2C19 in East-and Southern African populations including psychiatric patients
-
Dandara, C., Masimirembwa, C. M., Magimba, A., Sayi, J., Kaaya, S., Sommers, D. K., Snyman, J. R. and Hasler, J. A.: Genetic polymorphism of CYP2D6 and CYP2C19 in East-and Southern African populations including psychiatric patients. Eur. J. Clin. Pharmacol., 57: 11-17 (2001).
-
(2001)
Eur. J. Clin. Pharmacol.
, vol.57
, pp. 11-17
-
-
Dandara, C.1
Masimirembwa, C.M.2
Magimba, A.3
Sayi, J.4
Kaaya, S.5
Sommers, D.K.6
Snyman, J.R.7
Hasler, J.A.8
-
108
-
-
0032299995
-
High frequency of CYP2D6 poor and “intermediate” metabolizers in black populations: a review and preliminary data
-
Bradford, L. D., Gaedigk, A. and Leeder, J. S.: High frequency of CYP2D6 poor and “intermediate” metabolizers in black populations: a review and preliminary data. Psychopharmacol. Bull., 34: 797-804 (1998).
-
(1998)
Psychopharmacol. Bull.
, vol.34
, pp. 797-804
-
-
Bradford, L.D.1
Gaedigk, A.2
Leeder, J.S.3
-
109
-
-
4244171500
-
CYP2D6 allele frequencies in African Americans: phenotype concordance with dextromethorphan
-
Forbes, N. S., Bradford, L. D., Gotschall, R. R., Leeder, J. S. and Gaedigk, A.: CYP2D6 allele frequencies in African Americans: phenotype concordance with dextromethorphan. Clin. Pharmacol. Ther., 65: 170 (1999).
-
(1999)
Clin. Pharmacol. Ther.
, vol.65
, pp. 170
-
-
Forbes, N.S.1
Bradford, L.D.2
Gotschall, R.R.3
Leeder, J.S.4
Gaedigk, A.5
-
110
-
-
0033408498
-
Analysis of the CYP2D6 gene mutation and their consequences for enzyme function in a West African population
-
Griese, E. U., Asante-Poku, S., Ofori-Adjei, D., Mikus, G. and Eichelbaum, M.: Analysis of the CYP2D6 gene mutation and their consequences for enzyme function in a West African population. Pharmacogenetics, 9: 715-723 (1999).
-
(1999)
Pharmacogenetics
, vol.9
, pp. 715-723
-
-
Griese, E.U.1
Asante-Poku, S.2
Ofori-Adjei, D.3
Mikus, G.4
Eichelbaum, M.5
-
111
-
-
0029850096
-
Phenotype and genotype analysis of debrisoquine hydroxylase (CYP2Din a black zimbabwean population. Reduced enzyme activity and evaluation of metabolic correlation of CYP2D6 probe drugs
-
Masimirembwa, C., Hasler, J., Bertilssons, L., Johansson, I., Ekberg, O. and Ingelman-Sundberg, M.: Phenotype and genotype analysis of debrisoquine hydroxylase (CYP2Din a black zimbabwean population. Reduced enzyme activity and evaluation of metabolic correlation of CYP2D6 probe drugs. Eur. J. Clin. Pharmacol., 51: 117-122 (1996).
-
(1996)
Eur. J. Clin. Pharmacol.
, vol.51
, pp. 117-122
-
-
Masimirembwa, C.1
Hasler, J.2
Bertilssons, L.3
Johansson, I.4
Ekberg, O.5
Ingelman-Sundberg, M.6
-
112
-
-
0030432585
-
Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles
-
Akillu, E., Persson, I., Bertilsson, L., Johansson, I., Rodrigues, F. and Ingelman-Sundberg, M.: Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles. J. Pharmacol. Exp. Ther., 278: 441-446 (1996).
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.278
, pp. 441-446
-
-
Akillu, E.1
Persson, I.2
Bertilsson, L.3
Johansson, I.4
Rodrigues, F.5
Ingelman-Sundberg, M.6
-
113
-
-
0032868321
-
Phenotypes and genotypes for CYP2D6 and CYP2C19 in a black Tanzanian population
-
Bathum, L., Skjelbo, E., Matabingwa, T. K., Madsen, H., Horder, M. and Brosen, K.: Phenotypes and genotypes for CYP2D6 and CYP2C19 in a black Tanzanian population. Br. J. Clin. Pharmacol., 48: 395-401 (1999).
-
(1999)
Br. J. Clin. Pharmacol.
, vol.48
, pp. 395-401
-
-
Bathum, L.1
Skjelbo, E.2
Matabingwa, T.K.3
Madsen, H.4
Horder, M.5
Brosen, K.6
-
114
-
-
0029853664
-
A novel mutant variant of the CYP2D6 gene (CYP2D6*common in a black African population: association with diminished debrisoquine hydroxylase activity
-
Masimirembwa, C., Persson, I., Bertilsson, L., Hasler, J. and Ingelman-Sundberg, M.: A novel mutant variant of the CYP2D6 gene (CYP2D6*common in a black African population: association with diminished debrisoquine hydroxylase activity. Br. J. Clin. Pharmacol., 42: 713-719 (1996).
-
(1996)
Br. J. Clin. Pharmacol.
, vol.42
, pp. 713-719
-
-
Masimirembwa, C.1
Persson, I.2
Bertilsson, L.3
Hasler, J.4
Ingelman-Sundberg, M.5
-
115
-
-
0030462277
-
S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians
-
Persson, I., Aklillu, E., Rodrigues, F., Bertilsson, L. and Ingelman-Sundberg, M.: S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians. Pharmacogenetics, 6: 521-526 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 521-526
-
-
Persson, I.1
Aklillu, E.2
Rodrigues, F.3
Bertilsson, L.4
Ingelman-Sundberg, M.5
-
116
-
-
13144258722
-
Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype
-
Herrlin, K., Massele, A. Y., Jande, M., Alm, C., Tybring, G., Abdi, Y. A., Wennerholm, A., Johansson, I., Dahl, M.-L., Bertilsson, L. and Gustafsson, L. L.: Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype. Clin. Pharmacol. Ther., 64: 391-401 (1998).
-
(1998)
Clin. Pharmacol. Ther.
, vol.64
, pp. 391-401
-
-
Herrlin, K.1
Massele, A.Y.2
Jande, M.3
Alm, C.4
Tybring, G.5
Abdi, Y.A.6
Wennerholm, A.7
Johansson, I.8
Dahl, M.-L.9
Bertilsson, L.10
Gustafsson, L.L.11
-
117
-
-
0029055448
-
Phenotyping and genotyping of S-mephenytoin hydroxylase (cytochrome P450 2Cin a Shona population of Zimbabwe
-
Masimirembwa, C., Bertilsson, L., Johansson, I., Hasler, J. A. and Ingelman-sundberg, M.: Phenotyping and genotyping of S-mephenytoin hydroxylase (cytochrome P450 2Cin a Shona population of Zimbabwe. Clin. Pharmacol. Ther., 57: 656-661 (1995).
-
(1995)
Clin. Pharmacol. Ther.
, vol.57
, pp. 656-661
-
-
Masimirembwa, C.1
Bertilsson, L.2
Johansson, I.3
Hasler, J.A.4
Ingelman-sundberg, M.5
-
118
-
-
0029775045
-
Genetic polymorphism of S-mephenytoin 4?-hydroxylation in African-Americans
-
Edeki, T. I., Goldstein, J. A., de Morais, S. M. F., Hajiloo, L., Butler, M., Chapdelaine, P. and Wilkinson, G. R.: Genetic polymorphism of S-mephenytoin 4?-hydroxylation in African-Americans. Pharmacogenetics, 6: 357-360 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 357-360
-
-
Edeki, T.I.1
Goldstein, J.A.2
de Morais, S.M.F.3
Hajiloo, L.4
Butler, M.5
Chapdelaine, P.6
Wilkinson, G.R.7
-
119
-
-
0030811291
-
Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians
-
McLellan, R. A., Oscarson, M., Seidegard, J., Evans, D. A. and Ingelman-Sundberg, M.: Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians. Pharmacogenetics, 7: 187-191 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 187-191
-
-
McLellan, R.A.1
Oscarson, M.2
Seidegard, J.3
Evans, D.A.4
Ingelman-Sundberg, M.5
-
120
-
-
0033063954
-
CYP2D6 polymorphism in systemic lupus erythematosus patients
-
Kortunay, S., Bozkurt, A., Bathum, L., Basci, N. E., Calguneri, M., Brosen, K. and Kayaalp,S. O.: CYP2D6 polymorphism in systemic lupus erythematosus patients. Eur. J. Clin. Pharmacol., 55: 21-25 (1999).
-
(1999)
Eur. J. Clin. Pharmacol.
, vol.55
, pp. 21-25
-
-
Kortunay, S.1
Bozkurt, A.2
Bathum, L.3
Basci, N.E.4
Calguneri, M.5
Brosen, K.6
Kayaalp, S.O.7
-
121
-
-
0028355765
-
Debrisoquine 4-hydroxylation (CYP2Dpolymorphism in Jordanians
-
Hadidi, H. F., Cholerton, S., Monkman, S. C., Armstrong, M., Irshåid, Y. M., Rawashdeh, N. M., Daly, A. K. and Idle, J. R.: Debrisoquine 4-hydroxylation (CYP2Dpolymorphism in Jordanians. Pharmacogenetics, 4: 159-161 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 159-161
-
-
Hadidi, H.F.1
Cholerton, S.2
Monkman, S.C.3
Armstrong, M.4
Irshåid, Y.M.5
Rawashdeh, N.M.6
Daly, A.K.7
Idle, J.R.8
-
122
-
-
0032908379
-
CYP2C19 genotype does not represent a genetic predisposition in idiopathic systemic lupus erythematosus
-
Kortunay, S., Bozkurt, A., Bathum, L., Basci, N. E., Calgüneri, M., Brosen, K. and Kayaap, S. O.: CYP2C19 genotype does not represent a genetic predisposition in idiopathic systemic lupus erythematosus. Ann. Rheum. Dis., 58: 182-185 (1999).
-
(1999)
Ann. Rheum. Dis.
, vol.58
, pp. 182-185
-
-
Kortunay, S.1
Bozkurt, A.2
Bathum, L.3
Basci, N.E.4
Calgüneri, M.5
Brosen, K.6
Kayaap, S.O.7
-
123
-
-
2042431033
-
Phenotypic-genotypic analysis of CYP2C19 in the Jewish Israeli population
-
Sviri, S., Shpizen, S., Leitersdorf, E., Levy, M. and Caraco, Y.: Phenotypic-genotypic analysis of CYP2C19 in the Jewish Israeli population. Clin. Pharmacol. Ther., 65: 275-282 (1999).
-
(1999)
Clin. Pharmacol. Ther.
, vol.65
, pp. 275-282
-
-
Sviri, S.1
Shpizen, S.2
Leitersdorf, E.3
Levy, M.4
Caraco, Y.5
-
124
-
-
0018947130
-
Ethnic difference in drug metabolism: debrisoquine 4-hydroxylation in Caucasians and Orientals
-
Kalow, W., Otton, S. V., Kadar, D., Endrenyi, L. and Inaba, T.: Ethnic difference in drug metabolism: debrisoquine 4-hydroxylation in Caucasians and Orientals. Can. J. Physiol. Pharmacol., 58: 1142-1144 (1980).
-
(1980)
Can. J. Physiol. Pharmacol.
, vol.58
, pp. 1142-1144
-
-
Kalow, W.1
Otton, S.V.2
Kadar, D.3
Endrenyi, L.4
Inaba, T.5
-
125
-
-
0025004458
-
Debrisoquine hydroxylation and sulfamethazine acetylation in a Chinese population
-
Xu, X.-M. and Jiang, W.-D.: Debrisoquine hydroxylation and sulfamethazine acetylation in a Chinese population. Acta. Pharmacol. Sinica., 11: 385-388 (1990).
-
(1990)
Acta. Pharmacol. Sinica.
, vol.11
, pp. 385-388
-
-
Xu, X.-M.1
Jiang, W.-D.2
-
126
-
-
0025794009
-
Pharmacogenetics and drug metabolism: An Irish perspective
-
Holland, P., Barry, M. and Feely, J.: Pharmacogenetics and drug metabolism: An Irish perspective. Ir. J. Med. Sci., 160: 54-56 (1991).
-
(1991)
Ir. J. Med. Sci.
, vol.160
, pp. 54-56
-
-
Holland, P.1
Barry, M.2
Feely, J.3
-
127
-
-
0019515321
-
Debrisoquine hydroxylation capacity: Problems of assessment in two populations
-
Inaba, T., Otton, S. V., Sc, M. and Kalow, W.: Debrisoquine hydroxylation capacity: Problems of assessment in two populations. Clin. Pharmacol. Ther., 29: 218-223 (1981).
-
(1981)
Clin. Pharmacol. Ther.
, vol.29
, pp. 218-223
-
-
Inaba, T.1
Otton, S.V.2
Sc, M.3
Kalow, W.4
-
128
-
-
0025308115
-
Evidence for the polymorphic oxidation of debrisoquine in the Thai population
-
Wanwimolruk, S., Patamasucon, P. and Lee, E. J. D.: Evidence for the polymorphic oxidation of debrisoquine in the Thai population. Br. J. Clin. Pharmacol., 29: 244-247 (1990).
-
(1990)
Br. J. Clin. Pharmacol.
, vol.29
, pp. 244-247
-
-
Wanwimolruk, S.1
Patamasucon, P.2
Lee, E.J.D.3
-
129
-
-
0024212165
-
Oxidation phenotyping in Chinese and Malay populations
-
Lee, E. J. D., Nam, Y. P. and Hee, G. N.: Oxidation phenotyping in Chinese and Malay populations. Clin. Exp. Pharmacol. Psysiol., 15: 889-891 (1988).
-
(1988)
Clin. Exp. Pharmacol. Psysiol.
, vol.15
, pp. 889-891
-
-
Lee, E.J.D.1
Nam, Y.P.2
Hee, G.N.3
-
130
-
-
0034536960
-
CYP2D6 phenotypes among Malays in Malaysia
-
Ismail, R., Hussein, A., The, L. K. and Isa, M. N.: CYP2D6 phenotypes among Malays in Malaysia. J. Clin. Pharm. Ther., 25: 379-383 (2000).
-
(2000)
J. Clin. Pharm. Ther.
, vol.25
, pp. 379-383
-
-
Ismail, R.1
Hussein, A.2
The, L.K.3
Isa, M.N.4
-
131
-
-
0025890423
-
Genetic analysis of the interethnic difference between Chinese and Caucasians in the polymorphic metabolism of debrisoquine and codeine
-
Johansson, I., Yue, Q. Y., Dahl, M.-L., Heim, M., Säwe, J., Bertilsson, L., Meyer, U. A., Sjæqvist, F. and Ingelman-Sundberg, M.: Genetic analysis of the interethnic difference between Chinese and Caucasians in the polymorphic metabolism of debrisoquine and codeine. Eur. J. Clin. Pharmacol., 40: 553-556 (1991).
-
(1991)
Eur. J. Clin. Pharmacol.
, vol.40
, pp. 553-556
-
-
Johansson, I.1
Yue, Q.Y.2
Dahl, M.-L.3
Heim, M.4
Säwe, J.5
Bertilsson, L.6
Meyer, U.A.7
Sjæqvist, F.8
Ingelman-Sundberg, M.9
-
132
-
-
0029146759
-
Evidence for the polymorphic oxidation of debrisoquine and proguanil in a Khmer (Cambodian) population
-
Wanwimolruk, S., Thou, M. R. and Woods, D. J.: Evidence for the polymorphic oxidation of debrisoquine and proguanil in a Khmer (Cambodian) population. Br. J. Clin. Pharmacol., 40: 166-169 (1995).
-
(1995)
Br. J. Clin. Pharmacol.
, vol.40
, pp. 166-169
-
-
Wanwimolruk, S.1
Thou, M.R.2
Woods, D.J.3
-
133
-
-
0022178173
-
Interethnic differences in genetic polymorphism of debrisoquine and mephenytoin hydroxylation between Japanese and Caucasian populations
-
Nakamura, K., Goto, F., Ray, W. A., McAllister, C. B., Jacqz, M. D., Wilkinson, G. R. and Branch, R. A.: Interethnic differences in genetic polymorphism of debrisoquine and mephenytoin hydroxylation between Japanese and Caucasian populations. Clin. Pharmacol. Ther., 38: 402-408 (1985).
-
(1985)
Clin. Pharmacol. Ther.
, vol.38
, pp. 402-408
-
-
Nakamura, K.1
Goto, F.2
Ray, W.A.3
McAllister, C.B.4
Jacqz, M.D.5
Wilkinson, G.R.6
Branch, R.A.7
-
134
-
-
0032767990
-
A new variant CYP2D6 allele (CYP2D6*with a single base insertion in exon 5 in a Japanese population associated with a poor metabolizer phenotype
-
Chiba, M., Yokoi, T., Nemoto, N., Inaba, M., Kinoshita, M. and Kamataki, T.: A new variant CYP2D6 allele (CYP2D6*with a single base insertion in exon 5 in a Japanese population associated with a poor metabolizer phenotype. Pharmacogenetics, 9: 287-293 (1999).
-
(1999)
Pharmacogenetics
, vol.9
, pp. 287-293
-
-
Chiba, M.1
Yokoi, T.2
Nemoto, N.3
Inaba, M.4
Kinoshita, M.5
Kamataki, T.6
-
135
-
-
0026506140
-
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
-
Bertilsson, L., Lou, Y.-Q., Du, Y.-L., Liu, Y., Kuang, T.-Y., Liao, X.-M., Wang, K.-Y., Reviriego, J., Iselius, L. and Sjoqvist, F.: Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin. Clin. Pharmacol. Ther., 51: 388-397 (1992).
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 388-397
-
-
Bertilsson, L.1
Lou, Y.-Q.2
Du, Y.-L.3
Liu, Y.4
Kuang, T.-Y.5
Liao, X.-M.6
Wang, K.-Y.7
Reviriego, J.8
Iselius, L.9
Sjoqvist, F.10
-
136
-
-
0027272518
-
Proguanil metabolism is determined by the mephenytoin oxidation polymorphism in Vietnamese living in Denmark
-
Brosen, K., Skjelbo, E. and Flachs, H: Proguanil metabolism is determined by the mephenytoin oxidation polymorphism in Vietnamese living in Denmark. Br. J. Clin. Pharmacol., 36: 105-108 (1993).
-
(1993)
Br. J. Clin. Pharmacol.
, vol.36
, pp. 105-108
-
-
Brosen, K.1
Skjelbo, E.2
Flachs, H.3
-
137
-
-
0023196290
-
Evidence for polymorphic oxidation of sparteine in Japanese subjects
-
Ishizaki, T., Eichelbaum, M., Horai, Y., Hashimoto, K., Chiba, K. and Dengler, H. J.: Evidence for polymorphic oxidation of sparteine in Japanese subjects. Br. J. Clin. Pharmacol., 23: 482-485 (1987).
-
(1987)
Br. J. Clin. Pharmacol.
, vol.23
, pp. 482-485
-
-
Ishizaki, T.1
Eichelbaum, M.2
Horai, Y.3
Hashimoto, K.4
Chiba, K.5
Dengler, H.J.6
-
138
-
-
0034061621
-
Genetic polymorphism of CYP2D6 in a Kera-lite (South India) population
-
Abraham, B. K., Adithan, C., Shashindran, C. H. and Vasu, S.: Genetic polymorphism of CYP2D6 in a Kera-lite (South India) population. Br. J. Clin. Pharmacol., 49: 285-288 (2000).
-
(2000)
Br. J. Clin. Pharmacol.
, vol.49
, pp. 285-288
-
-
Abraham, B.K.1
Adithan, C.2
Shashindran, C.H.3
Vasu, S.4
-
139
-
-
0032771799
-
Polymorphism of dextromethorphan oxidation in South Indian subjects
-
Mamidi, R.N.V.S., Satyavaheeswaran, S., Vakkalanka, S. V. S., Chaluvadi, M. R., Katneni, K., Brahmadevara, N., Damodarram, G. and Subramaniam, S.: Polymorphism of dextromethorphan oxidation in South Indian subjects. Clin. Pharmacol. Ther., 66: 193-200 (1999).
-
(1999)
Clin. Pharmacol. Ther.
, vol.66
, pp. 193-200
-
-
Mamidi, R.N.V.S.1
Satyavaheeswaran, S.2
Vakkalanka, S.V.S.3
Chaluvadi, M.R.4
Katneni, K.5
Brahmadevara, N.6
Damodarram, G.7
Subramaniam, S.8
-
140
-
-
0029682520
-
Pharmacokinetics and polymorphic oxidation of dextromethorphan in a Japanese population
-
Nagai, N., Kawakubo, T., Kaneko, F., Ishii, M., Shinohara, R., Saito, Y., Shimamura, H., Ohnishi, A. and Ogata, H.: Pharmacokinetics and polymorphic oxidation of dextromethorphan in a Japanese population. Biopharm. Drug Dispos., 17: 421-433 (1996).
-
(1996)
Biopharm. Drug Dispos.
, vol.17
, pp. 421-433
-
-
Nagai, N.1
Kawakubo, T.2
Kaneko, F.3
Ishii, M.4
Shinohara, R.5
Saito, Y.6
Shimamura, H.7
Ohnishi, A.8
Ogata, H.9
-
141
-
-
0030985006
-
CYP2D6 phenotype and genotype in a Canadian native Indian population
-
Nowak, M. P., Tyndale, R. F. and Sellers, E. M.: CYP2D6 phenotype and genotype in a Canadian native Indian population. Pharmacogenetics, 7: 145-148 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 145-148
-
-
Nowak, M.P.1
Tyndale, R.F.2
Sellers, E.M.3
-
142
-
-
0030747181
-
Dextromethorphan metabolic phenotyping in a Chinese population
-
Cai, W.-M., Chen, B., Liu, Y.-X. and Chu, X.: Dextromethorphan metabolic phenotyping in a Chinese population. Acta Pharmacol. Sin., 18: 441-444 (1997).
-
(1997)
Acta Pharmacol. Sin.
, vol.18
, pp. 441-444
-
-
Cai, W.-M.1
Chen, B.2
Liu, Y.-X.3
Chu, X.4
-
143
-
-
0029119586
-
Comparison of the prevalence of the poor metabolizer phenotype for CYP2D6 between 203 hmong subjects and 280 white subjects residing in Minnesota
-
Straka, R. J., Hansen, S. R., and Walker, P. F.: Comparison of the prevalence of the poor metabolizer phenotype for CYP2D6 between 203 hmong subjects and 280 white subjects residing in Minnesota. Clin. Pharmacol. Ther., 58: 29-34 (1995).
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 29-34
-
-
Straka, R.J.1
Hansen, S.R.2
Walker, P.F.3
-
144
-
-
0029042294
-
The mephenytoin (cytochrome P450 2Cand dextromethorphan (cytochrome P450 2Dpolymorphisms in Saudi Arabians and Filipinos
-
Evans, D. A., Krahn, P. and Narayanan, N.: The mephenytoin (cytochrome P450 2Cand dextromethorphan (cytochrome P450 2Dpolymorphisms in Saudi Arabians and Filipinos. Pharmacogenetics, 5: 64-71 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 64-71
-
-
Evans, D.A.1
Krahn, P.2
Narayanan, N.3
-
145
-
-
0034088009
-
Genetic polymorphism of CYP2D6 in Karnataka and Andhra Pradesh population in India
-
Abraham, B. K., Adithan, C., Kiran, P.U., Mohammed, A.S.A.D. and Koumaravelou, K.: Genetic polymorphism of CYP2D6 in Karnataka and Andhra Pradesh population in India. Acta. Pharmacol. Sin., 21: 494-498 (2000).
-
(2000)
Acta. Pharmacol. Sin.
, vol.21
, pp. 494-498
-
-
Abraham, B.K.1
Adithan, C.2
Kiran, P.U.3
Mohammed, A.S.A.D.4
Koumaravelou, K.5
-
146
-
-
0032429357
-
Genetic polymorphism of CYP2D6 in North Indian subjects
-
Lamba, V., Lamba, J. K., Dilawari, J. B. and Kohli, K. K.: Genetic polymorphism of CYP2D6 in North Indian subjects. Eur. J. Clin. Pharmacol., 54: 787-791 (1998).
-
(1998)
Eur. J. Clin. Pharmacol.
, vol.54
, pp. 787-791
-
-
Lamba, V.1
Lamba, J.K.2
Dilawari, J.B.3
Kohli, K.K.4
-
147
-
-
0028030327
-
Dapsone N-acetylation, metoprolol a-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: A cocktail and extended phenotyping assessment trial
-
Setiabudy, R., Kusaka, M., Chiba, K., Darmansjah, I. and Ishizaki, T.: Dapsone N-acetylation, metoprolol a-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: A cocktail and extended phenotyping assessment trial. Clin. Pharmacol. Ther., 56: 142-153 (1994).
-
(1994)
Clin. Pharmacol. Ther.
, vol.56
, pp. 142-153
-
-
Setiabudy, R.1
Kusaka, M.2
Chiba, K.3
Darmansjah, I.4
Ishizaki, T.5
-
148
-
-
0034088327
-
Relationship of paroxetine disposition to metoprolol metabolic ratio and CYP2D6*10 genotype of Korean subjects
-
Yoon, Y.-R., Cha, I.-J., Shon, J.-H., Kim, K.-A., Cha, Y.-N., Jang, I.-J., Park, C.-W., Shin, S.-G., Folckhart, D. A. and Shin, J.-G.: Relationship of paroxetine disposition to metoprolol metabolic ratio and CYP2D6*10 genotype of Korean subjects. Clin. Pharmacol. Ther., 67: 567-576 (2000).
-
(2000)
Clin. Pharmacol. Ther.
, vol.67
, pp. 567-576
-
-
Yoon, Y.-R.1
Cha, I.2
Shon, J.-H.3
Kim, K.-A.4
Cha, Y.-N.5
Jang, I.-J.6
Park, C.-W.7
Shin, S.-G.8
Folckhart, D.A.9
Shin, J.-G.10
-
149
-
-
0029052267
-
Metoprolol a-hydroxylation capacity in 96 Chinese Han volunteers
-
Tu, Z.-G. and Zhao, L.-L.: Metoprolol a-hydroxylation capacity in 96 Chinese Han volunteers. Chung Kuo Yao Li Hsueh Pao, 16: 325-329 (1995).
-
(1995)
Chung Kuo Yao Li Hsueh Pao
, vol.16
, pp. 325-329
-
-
Tu, Z.-G.1
Zhao, L.-L.2
-
150
-
-
0024442372
-
Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese
-
Horai, Y., Nakano, M., Ishizaki, T., Ishikawa, K., Zhou, H.-H., Zhou, B.-J., Liao, C.-L. and Zhang, L.-M.: Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese. Clin. Pharmacol. Ther., 46: 198-207 (1989).
-
(1989)
Clin. Pharmacol. Ther.
, vol.46
, pp. 198-207
-
-
Horai, Y.1
Nakano, M.2
Ishizaki, T.3
Ishikawa, K.4
Zhou, H.-H.5
Zhou, B.-J.6
Liao, C.-L.7
Zhang, L.-M.8
-
151
-
-
8244236213
-
Study on metoprolol metabolism in a Chinese population of healthy volunteers
-
Zhang, Y.-Y. and Jiang, W.-D.: Study on metoprolol metabolism in a Chinese population of healthy volunteers. Chin. J. Clin. Pharmacol., 6: 158-164 (1990).
-
(1990)
Chin. J. Clin. Pharmacol.
, vol.6
, pp. 158-164
-
-
Zhang, Y.-Y.1
Jiang, W.-D.2
-
152
-
-
0026091975
-
Metoprolol oxidation polymorphism in a Korean population: comparison with native Japanese and Chinese populations
-
Sohn, D.-R., Shin, S.-G., Park, C.-W., Kusaka, M., Chiba, K. and Ishizaki, T.: Metoprolol oxidation polymorphism in a Korean population: comparison with native Japanese and Chinese populations. Br. J. Clin. Pharmacol., 32: 504-507 (1991).
-
(1991)
Br. J. Clin. Pharmacol.
, vol.32
, pp. 504-507
-
-
Sohn, D.-R.1
Shin, S.-G.2
Park, C.-W.3
Kusaka, M.4
Chiba, K.5
Ishizaki, T.6
-
153
-
-
0022220338
-
Genetic polymorphism of mephenytoin p(4?)-hydroxylation: difference between Orientals and Caucasians
-
Jurima, M., Inaba, T., Kadar, D. and Kalow, W.: Genetic polymorphism of mephenytoin p(4?)-hydroxylation: difference between Orientals and Caucasians. Br. J. Clin. Pharmacol., 19: 483-487 (1985).
-
(1985)
Br. J. Clin. Pharmacol.
, vol.19
, pp. 483-487
-
-
Jurima, M.1
Inaba, T.2
Kadar, D.3
Kalow, W.4
-
154
-
-
0029886472
-
Genetic polymorphism of 4?-hydroxylation of S-mephenytoin in 148 Chinese of Han nationality
-
Ruan, Z.-R., Cheng, Y.-S., Zhou, J.-F., Zhao, Y., Pan, Y.-Z. and Ding, D.-Y.: Genetic polymorphism of 4?-hydroxylation of S-mephenytoin in 148 Chinese of Han nationality. Acta Pharmacol. Sin., 17: 119-121 (1996).
-
(1996)
Acta Pharmacol. Sin.
, vol.17
, pp. 119-121
-
-
Ruan, Z.-R.1
Cheng, Y.-S.2
Zhou, J.-F.3
Zhao, Y.4
Pan, Y.-Z.5
Ding, D.-Y.6
-
155
-
-
0030909951
-
Evidence for the effect of gender on activity of (S)-mephenytoin 4?-hydroxylase (CYP2Cin a Chinese population
-
Xie, H.-G., Huang, S.-L., Xu, Z.-H., Xiao, Z.-S., He, N. and Zhou, H.-H.: Evidence for the effect of gender on activity of (S)-mephenytoin 4?-hydroxylase (CYP2Cin a Chinese population. Pharmacogenetics, 7: 115-119 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 115-119
-
-
Xie, H.-G.1
Huang, S.-L.2
Xu, Z.-H.3
Xiao, Z.-S.4
He, N.5
Zhou, H.-H.6
-
156
-
-
0026705708
-
Incidence of S-mephenytoin hydroxylation deficiency in Korean population and the interphenotypic differences in diazepam pharmacokinetics
-
Sohn, D.-R., Kusaka, M., Ishizaki, T., Shin, S.-G., Jang, I.-J., Shin, J.-G. and Chiba, K.: Incidence of S-mephenytoin hydroxylation deficiency in Korean population and the interphenotypic differences in diazepam pharmacokinetics. Clin. Pharmacol. Ther., 52: 160-169 (1992).
-
(1992)
Clin. Pharmacol. Ther.
, vol.52
, pp. 160-169
-
-
Sohn, D.-R.1
Kusaka, M.2
Ishizaki, T.3
Shin, S.-G.4
Jang, I.-J.5
Shin, J.-G.6
Chiba, K.7
-
157
-
-
0030748504
-
The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin
-
Sarich, T., Kalhorn, T., Magee, S., Al-Sayegh, F., Adams, S., Slattery, J., Goldsstein, J., Nelson, S. and Wright, J.: The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin. Clin. Pharmacol. Ther., 62: 21-28 (1997).
-
(1997)
Clin. Pharmacol. Ther.
, vol.62
, pp. 21-28
-
-
Sarich, T.1
Kalhorn, T.2
Magee, S.3
Al-Sayegh, F.4
Adams, S.5
Slattery, J.6
Goldsstein, J.7
Nelson, S.8
Wright, J.9
-
158
-
-
0025086218
-
Frequency of impaired mephenytoin 4?-hydroxylation in an Indian population
-
Doshi, B. S., Kulkarni, R. D. and Chauhan, B. L.: Frequency of impaired mephenytoin 4?-hydroxylation in an Indian population. Br. J. Clin. Pharmacol., 30: 779-780 (1990).
-
(1990)
Br. J. Clin. Pharmacol.
, vol.30
, pp. 779-780
-
-
Doshi, B.S.1
Kulkarni, R.D.2
Chauhan, B.L.3
-
159
-
-
0026240125
-
Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502Dphenotypes
-
Daly, A. K., Armstrong, M., Monkman, S. C., Idle, M. E. and Idle, J. R.: Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502Dphenotypes. Pharmacogenetics, 1: 33-41 (1991).
-
(1991)
Pharmacogenetics
, vol.1
, pp. 33-41
-
-
Daly, A.K.1
Armstrong, M.2
Monkman, S.C.3
Idle, M.E.4
Idle, J.R.5
-
160
-
-
0025869532
-
Relation between debrisoquine oxidation phenotype and morphological, biological, and pathological variables in a large population
-
Vincent-Viry, M., Muller, J., Fournier, B., Galteau, M. M. and Siest, G.: Relation between debrisoquine oxidation phenotype and morphological, biological, and pathological variables in a large population. Clin. Chem., 37: 327-332 (1991).
-
(1991)
Clin. Chem.
, vol.37
, pp. 327-332
-
-
Vincent-Viry, M.1
Muller, J.2
Fournier, B.3
Galteau, M.M.4
Siest, G.5
-
161
-
-
0023616472
-
Prevalence of drug hydroxylator phenotypes in Belgium
-
Leclercq, V., Desager, J. P., van Nieuwenhuyze, Y. and Harvengt, C.: Prevalence of drug hydroxylator phenotypes in Belgium. Eur. J. Clin. Pharmacol., 33: 439-440 (1987).
-
(1987)
Eur. J. Clin. Pharmacol.
, vol.33
, pp. 439-440
-
-
Leclercq, V.1
Desager, J.P.2
van Nieuwenhuyze, Y.3
Harvengt, C.4
-
162
-
-
0028920832
-
Debrisoquine hydroxylation in a Polish population
-
Kunicki, P. K., Sitkiewicz, D., Pawlik, A., Bielicka-Sulzyc, V., Borowiecka, E., Gawrońska-Szklarz, B., Sterna, R., Matsumoto, H. and Radziwon-Zaleska, M.: Debrisoquine hydroxylation in a Polish population. Eur. J. Clin. Pharmacol., 47: 503-505 (1995).
-
(1995)
Eur. J. Clin. Pharmacol.
, vol.47
, pp. 503-505
-
-
Kunicki, P.K.1
Sitkiewicz, D.2
Pawlik, A.3
Bielicka-Sulzyc, V.4
Borowiecka, E.5
Gawrońska-Szklarz, B.6
Sterna, R.7
Matsumoto, H.8
Radziwon-Zaleska, M.9
-
163
-
-
0023054696
-
A debrisoquine hydroxilacio polimorfizmusanak vizsgala-ta
-
Béla, G., Kálmán, R., ádám, V. and Antal, E. K.: A debrisoquine hydroxilacio polimorfizmusanak vizsgala-ta. Orv. Hetil., 127: 2299-2301 (1986).
-
(1986)
Orv. Hetil.
, vol.127
, pp. 2299-2301
-
-
Béla, G.1
Kálmán, R.2
ádám, V.3
Antal, E.K.4
-
164
-
-
0022408175
-
Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
-
Barbeau, A., Cloutier, T., Roy, M., Plasse, L., Paris, S. and Poirier, J.: Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine. Lancet 30: 1213-1215 (1985).
-
(1985)
Lancet
, vol.30
, pp. 1213-1215
-
-
Barbeau, A.1
Cloutier, T.2
Roy, M.3
Plasse, L.4
Paris, S.5
Poirier, J.6
-
165
-
-
0023024516
-
Debrisoquine oxidation in an Australian population
-
Peart, G. F., Boutagy, J. and Shenfield, G. M.: Debrisoquine oxidation in an Australian population. Br. J. Clin. Pharmacol., 21: 465-471 (1986).
-
(1986)
Br. J. Clin. Pharmacol.
, vol.21
, pp. 465-471
-
-
Peart, G.F.1
Boutagy, J.2
Shenfield, G.M.3
-
166
-
-
0026584955
-
Polymorphism of debrisoquine oxidation in New Zealand Caucasians
-
Wanwimolruk, S., Denton, J. R., Ferry, D. G. and Beasley, M.: Polymorphism of debrisoquine oxidation in New Zealand Caucasians. Eur. J. Clin. Pharmacol., 42: 349-350 (1992).
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.42
, pp. 349-350
-
-
Wanwimolruk, S.1
Denton, J.R.2
Ferry, D.G.3
Beasley, M.4
-
167
-
-
0025857589
-
Lack of relationship between the polymorphism of debrisoquine oxidation and lung cancer
-
Duché, J.-C., Joanne, C., Barré, J., de Cremoux, H., Ddalphine, J. C., Depierre, A., Brochard, P., Tillement, J. P. and Bechtel, P.: Lack of relationship between the polymorphism of debrisoquine oxidation and lung cancer. Br. J. Clin. Pharmacol., 31: 533-536 (1991).
-
(1991)
Br. J. Clin. Pharmacol.
, vol.31
, pp. 533-536
-
-
Duché, J.-C.1
Joanne, C.2
Barré, J.3
de Cremoux, H.4
Ddalphine, J.C.5
Depierre, A.6
Brochard, P.7
Tillement, J.P.8
Bechtel, P.9
-
168
-
-
0024230858
-
Polymorphism of debrisoquine hydroxylation among Finns and Lapps
-
Arvela, P., Kirjarinta, M., Kirjarinta, M., Karki, N. and Pelkonen, O.: Polymorphism of debrisoquine hydroxylation among Finns and Lapps. Br. J. Clin. Pharmacol., 26: 601-603 (1988).
-
(1988)
Br. J. Clin. Pharmacol.
, vol.26
, pp. 601-603
-
-
Arvela, P.1
Kirjarinta, M.2
Kirjarinta, M.3
Karki, N.4
Pelkonen, O.5
-
169
-
-
0024269725
-
Debrisoquine oxidation in a Finnish population: the effect of oral contraceptive on the metabolic ratio
-
Kallio, J., Lindberg, R., Huupponen, R. and Iisalo, E.: Debrisoquine oxidation in a Finnish population: the effect of oral contraceptive on the metabolic ratio. Br. J. Clin. Pharmacol., 26: 791-795 (1988).
-
(1988)
Br. J. Clin. Pharmacol.
, vol.26
, pp. 791-795
-
-
Kallio, J.1
Lindberg, R.2
Huupponen, R.3
Iisalo, E.4
-
170
-
-
0018900001
-
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population
-
Evans, D. A. P., Mahgoub, A., Sloan, T. P. and Idle, J. R.: A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population. J. Med. Genet., 17: 102-105 (1980).
-
(1980)
J. Med. Genet.
, vol.17
, pp. 102-105
-
-
Evans, D.A.P.1
Mahgoub, A.2
Sloan, T.P.3
Idle, J.R.4
-
171
-
-
0026781283
-
Debrisoquine hydroxylation in Parkinson's disease
-
Steiger, M. J., Lledo, P., Quinn, N. P., Marsden, C. D., Turner, P. and Jenner, P. G.: Debrisoquine hydroxylation in Parkinson's disease. Acta. Neurol. Scand., 86: 159-164 (1992).
-
(1992)
Acta. Neurol. Scand.
, vol.86
, pp. 159-164
-
-
Steiger, M.J.1
Lledo, P.2
Quinn, N.P.3
Marsden, C.D.4
Turner, P.5
Jenner, P.G.6
-
172
-
-
0024507618
-
Degenerative neurological disease and debrisoquine-4-hydroxylation capacity
-
Steventon, G. B., Heafield, M. T. E., Sturman, S. G., Waring, R. H., Williams, A. C. and Ellingham, J.: Degenerative neurological disease and debrisoquine-4-hydroxylation capacity. Med. Sci. Res., 17: 163-164 (1989).
-
(1989)
Med. Sci. Res.
, vol.17
, pp. 163-164
-
-
Steventon, G.B.1
Heafield, M.T.E.2
Sturman, S.G.3
Waring, R.H.4
Williams, A.C.5
Ellingham, J.6
-
173
-
-
0023640544
-
Acetylation and oxidation phenotypes in malignant lymphoma
-
Philip, P. A., Rogers, H. J. and Harper, P. G.: Acetylation and oxidation phenotypes in malignant lymphoma. Cancer Chemother. Pharmacol., 20: 235-238 (1987).
-
(1987)
Cancer Chemother. Pharmacol.
, vol.20
, pp. 235-238
-
-
Philip, P.A.1
Rogers, H.J.2
Harper, P.G.3
-
174
-
-
0024336503
-
S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin
-
Sanz, E. J., Villen, T., Alm, C., and Bertilsson, L.: S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin. Clin. Pharmacol. Ther., 45: 495-499 (1989).
-
(1989)
Clin. Pharmacol. Ther.
, vol.45
, pp. 495-499
-
-
Sanz, E.J.1
Villen, T.2
Alm, C.3
Bertilsson, L.4
-
175
-
-
0022918442
-
Polymorphic debrisoquine and mephenytoin hydroxylation in patients with pulmonary hypertension of vascular origin after aminorex fumarate
-
Saner, H., Gurtner, H. P., Preisig, R. and Kupfer, A.: Polymorphic debrisoquine and mephenytoin hydroxylation in patients with pulmonary hypertension of vascular origin after aminorex fumarate. Eur. J. Clin. Pharmacol., 31: 437-442 (1986).
-
(1986)
Eur. J. Clin. Pharmacol.
, vol.31
, pp. 437-442
-
-
Saner, H.1
Gurtner, H.P.2
Preisig, R.3
Kupfer, A.4
-
176
-
-
0027194527
-
Oxidative polymorphism of debrisoquine is not related to the risk of Alzheimer's disease
-
Benitez, J., Barquero, M. S., Coria, F., Molina, J. A., Jiménez-Jiménez, F. J. and Ladero, J. M.: Oxidative polymorphism of debrisoquine is not related to the risk of Alzheimer's disease. J. Neurol. Sci., 117: 8-11 (1993).
-
(1993)
J. Neurol. Sci.
, vol.117
, pp. 8-11
-
-
Benitez, J.1
Barquero, M.S.2
Coria, F.3
Molina, J.A.4
Jiménez-Jiménez, F.J.5
Ladero, J.M.6
-
177
-
-
0026040410
-
N-Acetylation and debrisoquine hydroxylation polymorphisms in patients with Gilbert's syndrome
-
Siegmund, W., Fengler, J. D., Franke, G., Zschiesche, M., Eike, O., Eike, E., Meisel, P. and Wulkkow, R.: N-Acetylation and debrisoquine hydroxylation polymorphisms in patients with Gilbert's syndrome. Br. J. Clin. Pharmacol., 32: 467-472 (1991).
-
(1991)
Br. J. Clin. Pharmacol.
, vol.32
, pp. 467-472
-
-
Siegmund, W.1
Fengler, J.D.2
Franke, G.3
Zschiesche, M.4
Eike, O.5
Eike, E.6
Meisel, P.7
Wulkkow, R.8
-
178
-
-
0025650435
-
N-acetylation and debrisoquine type oxidation polymorphism in Caucasians-with reference to age and sex
-
Siegmund, W., Hanke, W., Zschiesche, M., Franke, G., Biebler, K. E. and Wilke, A.: N-acetylation and debrisoquine type oxidation polymorphism in Caucasians-with reference to age and sex. Int. J. Clin. Pharmacol. Ther. Toxicol., 28: 504-509 (1990).
-
(1990)
Int. J. Clin. Pharmacol. Ther. Toxicol.
, vol.28
, pp. 504-509
-
-
Siegmund, W.1
Hanke, W.2
Zschiesche, M.3
Franke, G.4
Biebler, K.E.5
Wilke, A.6
-
179
-
-
0028018821
-
The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes
-
Bock, K. W., Schrenk, D., Forster, A., Griese, E.-U., Morike, K., Brockmeier, D. and Eichelbaum, M.: The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes. Pharmacogenetics, 4: 209-218 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 209-218
-
-
Bock, K.W.1
Schrenk, D.2
Forster, A.3
Griese, E.-U.4
Morike, K.5
Brockmeier, D.6
Eichelbaum, M.7
-
180
-
-
0020559087
-
The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions
-
Evans, D. A. P., Harmer, D., Downham, D. Y., Whibley, E. J., Idle, J. R., Ritchie, J. and Smith, R. L.: The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions. J. Med. Genet., 20: 321-329 (1983).
-
(1983)
J. Med. Genet.
, vol.20
, pp. 321-329
-
-
Evans, D.A.P.1
Harmer, D.2
Downham, D.Y.3
Whibley, E.J.4
Idle, J.R.5
Ritchie, J.6
Smith, R.L.7
-
181
-
-
0022517927
-
The genetic polymorphism of sparteine metabolism
-
Eichelbaum, M., Reetz, K. P., Schmidt, E. K. and Zekorn, C.: The genetic polymorphism of sparteine metabolism. Xenobiotica, 16: 465-481 (1986).
-
(1986)
Xenobiotica
, vol.16
, pp. 465-481
-
-
Eichelbaum, M.1
Reetz, K.P.2
Schmidt, E.K.3
Zekorn, C.4
-
182
-
-
0000775167
-
Poor metabolizer incidence of sparteine, mephenytoin and nifedipine in a dutch population as assessed by a “Cocktail” approach
-
Breimer, D. D., Danhof, M. and Schellens, J. H. M.: Poor metabolizer incidence of sparteine, mephenytoin and nifedipine in a dutch population as assessed by a “Cocktail” approach. Br. J. Pharmacol., 89: 478 (1986).
-
(1986)
Br. J. Pharmacol.
, vol.89
, pp. 478
-
-
Breimer, D.D.1
Danhof, M.2
Schellens, J.H.M.3
-
183
-
-
0028365855
-
Genetically determined sparteine oxidation polymorphism in a Polish population
-
Orzechowska-Juzwenko, K., Pawlik, J., Niewiński, P., Milejski, P., Dembowski, J., Turek, J., Goździk, A., Swiebodzki, L. and Hora, Z.: Genetically determined sparteine oxidation polymorphism in a Polish population. Eur. J. Clin. Pharmacol., 46: 481-483 (1994).
-
(1994)
Eur. J. Clin. Pharmacol.
, vol.46
, pp. 481-483
-
-
Orzechowska-Juzwenko, K.1
Pawlik, J.2
Niewiński, P.3
Milejski, P.4
Dembowski, J.5
Turek, J.6
Goździk, A.7
Swiebodzki, L.8
Hora, Z.9
-
184
-
-
0020034761
-
Sparteine metabolism in Canadian Caucasians
-
Vink, A., Tnaba, T., Otton, S. V. and Kalow, W.: Sparteine metabolism in Canadian Caucasians. Clin. Pharmacol. Ther., 31: 23-29 (1982).
-
(1982)
Clin. Pharmacol. Ther.
, vol.31
, pp. 23-29
-
-
Vink, A.1
Tnaba, T.2
Otton, S.V.3
Kalow, W.4
-
185
-
-
0035732937
-
Nicotine metabolism and CYP2D6 phenotype in smokers
-
Caporaso, N. E., Lerman, C., Audrain, J., Boyd, N. R., Main, D., Issaq, H. J., Utermahlan, B., Falk, R. T. and Shields, P.: Nicotine metabolism and CYP2D6 phenotype in smokers. Cancer Epidemiol. Biomarkers Prev., 10: 261-263 (2001).
-
(2001)
Cancer Epidemiol. Biomarkers Prev.
, vol.10
, pp. 261-263
-
-
Caporaso, N.E.1
Lerman, C.2
Audrain, J.3
Boyd, N.R.4
Main, D.5
Issaq, H.J.6
Utermahlan, B.7
Falk, R.T.8
Shields, P.9
-
186
-
-
0027234212
-
Dextromethorphan O-demethylation and dextrorphan glucuronidation in a French population
-
Duché, J.-C., Querol-Ferrer, V., Barré, J., Mesangeau, M. and Tillement, J.-P.: Dextromethorphan O-demethylation and dextrorphan glucuronidation in a French population. Int. J. Clin. Pharmacol. Ther. Toxicol., 31: 392-398 (1993).
-
(1993)
Int. J. Clin. Pharmacol. Ther. Toxicol.
, vol.31
, pp. 392-398
-
-
Duché, J.-C.1
Querol-Ferrer, V.2
Barré, J.3
Mesangeau, M.4
Tillement, J.-P.5
-
187
-
-
0032983850
-
CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: indications for oral contraceptive-related gender differences
-
Tamminga, W. J., Wemer, J., Oosterhuis, B., Wieling, J., Wilffert, B., de Leij, L.F.M.H., de Zeeuw, R. A. and Jonkman, J. H. G.: CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: indications for oral contraceptive-related gender differences. Eur. J. Clin. Pharmacol., 55: 177-184 (1999).
-
(1999)
Eur. J. Clin. Pharmacol.
, vol.55
, pp. 177-184
-
-
Tamminga, W.J.1
Wemer, J.2
Oosterhuis, B.3
Wieling, J.4
Wilffert, B.5
de Leij, L.F.M.H.6
de Zeeuw, R.A.7
Jonkman, J.H.G.8
-
188
-
-
0024541838
-
Phenotypic differences in dextromethorphan metabolism
-
Vetticaden, S. J., Cabana, B. E., Prasad, V. K., Purich, E. D., Jonkman, J. H. J., de Zeeuw, R., Ball, L., Leeson, L. J. and Braun, R. L.: Phenotypic differences in dextromethorphan metabolism. Pharm. Res., 6: 13-19 (1989).
-
(1989)
Pharm. Res.
, vol.6
, pp. 13-19
-
-
Vetticaden, S.J.1
Cabana, B.E.2
Prasad, V.K.3
Purich, E.D.4
Jonkman, J.H.J.5
de Zeeuw, R.6
Ball, L.7
Leeson, L.J.8
Braun, R.L.9
-
189
-
-
0028174309
-
CYP2D6-related oxidation polymorphism in Italy
-
Spina, E., Campo, G. M., Avenoso, A., Caputi, A. P. Zuccaro, P., Pacifici, R., Gatti, G., Strada, G., Bartoli, A. and Perucca, E.: CYP2D6-related oxidation polymorphism in Italy. Pharm. Res., 29: 281-289 (1994).
-
(1994)
Pharm. Res.
, vol.29
, pp. 281-289
-
-
Spina, E.1
Campo, G.M.2
Avenoso, A.3
Caputi, A.P.4
Zuccaro, P.5
Pacifici, R.6
Gatti, G.7
Strada, G.8
Bartoli, A.9
Perucca, E.10
-
190
-
-
0027477948
-
Polymorphism of debrisoquine and mephenytoin hydroxylation among Estonians
-
Kiivet, R. A., Svensson, J.-O., Bertilsson, L. and Sjoqvist, F.: Polymorphism of debrisoquine and mephenytoin hydroxylation among Estonians. Pharmacol. Toxicol., 72: 113-115 (1993).
-
(1993)
Pharmacol. Toxicol.
, vol.72
, pp. 113-115
-
-
Kiivet, R.A.1
Svensson, J.-O.2
Bertilsson, L.3
Sjoqvist, F.4
-
191
-
-
0033802124
-
Genetic polymorphism of CYP2D6 and CYP2C19 metabolism determined by phenotyping Israeli ethnic groups
-
Britzi, M., Bialer, M., Arcavi, L., Shachbari, A., Kapitulnik, T. and Soback, S.: Genetic polymorphism of CYP2D6 and CYP2C19 metabolism determined by phenotyping Israeli ethnic groups. Ther. Drug Monit., 22: 510-516 (2000).
-
(2000)
Ther. Drug Monit.
, vol.22
, pp. 510-516
-
-
Britzi, M.1
Bialer, M.2
Arcavi, L.3
Shachbari, A.4
Kapitulnik, T.5
Soback, S.6
-
192
-
-
0022338958
-
Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylation
-
Schmid, B., Bircher, J., Preisig, R. and Kupfer, A.: Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylation. Clin. Pharmacol. Ther., 38: 618-624 (1985).
-
(1985)
Clin. Pharmacol. Ther.
, vol.38
, pp. 618-624
-
-
Schmid, B.1
Bircher, J.2
Preisig, R.3
Kupfer, A.4
-
193
-
-
0024565089
-
Determination of dextromethorphan metabolizer phenotype in healthy volunteers
-
Hildebrand, M., Seifert, W. and Richenberger, A.: Determination of dextromethorphan metabolizer phenotype in healthy volunteers. Eur. J. Clin. Pharmacol., 36: 315-318 (1989).
-
(1989)
Eur. J. Clin. Pharmacol.
, vol.36
, pp. 315-318
-
-
Hildebrand, M.1
Seifert, W.2
Richenberger, A.3
-
194
-
-
0023762605
-
Phenotyping polymorphic drug metabolism in the French Caucasian population
-
Jacqz, E., Dulac, H. and Mathieu, H.: Phenotyping polymorphic drug metabolism in the French Caucasian population. Eur. J. Clin. Pharmacol., 35: 167-171 (1988).
-
(1988)
Eur. J. Clin. Pharmacol.
, vol.35
, pp. 167-171
-
-
Jacqz, E.1
Dulac, H.2
Mathieu, H.3
-
195
-
-
0026878915
-
Dextromethorphan O-demethylation in a large number of French Caucasian families
-
Vincent-Viry, M., Fournier, B., Siest, G. and Galteau, M. M.: Dextromethorphan O-demethylation in a large number of French Caucasian families. Pharmacogenetics, 2: 135-138 (1992).
-
(1992)
Pharmacogenetics
, vol.2
, pp. 135-138
-
-
Vincent-Viry, M.1
Fournier, B.2
Siest, G.3
Galteau, M.M.4
-
196
-
-
0023584439
-
Polymorphism of dextromethorphan oxidation in a French population
-
Larrey, D., Amouyal, G., Tinel, M., Letteron, P., Berson, A., Labbe, G. and Pessayre, D.: Polymorphism of dextromethorphan oxidation in a French population. Br. J. Clin. Pharmacol., 24: 676-679 (1987).
-
(1987)
Br. J. Clin. Pharmacol.
, vol.24
, pp. 676-679
-
-
Larrey, D.1
Amouyal, G.2
Tinel, M.3
Letteron, P.4
Berson, A.5
Labbe, G.6
Pessayre, D.7
-
197
-
-
0027265750
-
CYP2D6-and CYP3A-dependent metabolism of dextromethorphan in humans
-
Jacqz-Aigrain, E., Frunk-Brentano, C. and Cresteil, T.: CYP2D6-and CYP3A-dependent metabolism of dextromethorphan in humans. Pharmacogenetics, 3: 197-204 (1993).
-
(1993)
Pharmacogenetics
, vol.3
, pp. 197-204
-
-
Jacqz-Aigrain, E.1
Frunk-Brentano, C.2
Cresteil, T.3
-
198
-
-
0028998678
-
Phenotyping of CYP2C19 with enan-tiospecific HPLC-quatification of R-and S-mephenytoin and comparison with the intron4/exon5 G to A-splice site mutation
-
Brockmoller, J., Rost, K. L., Gross, D., Schenkel, A. and Roots, I.: Phenotyping of CYP2C19 with enan-tiospecific HPLC-quatification of R-and S-mephenytoin and comparison with the intron4/exon5 G to A-splice site mutation. Pharmacogenetics, 5: 80-88 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 80-88
-
-
Brockmoller, J.1
Rost, K.L.2
Gross, D.3
Schenkel, A.4
Roots, I.5
-
199
-
-
0027253112
-
Frequency of S-mephenytoin hydroxylation deficiency in 373 Spanish subjects compared to other Caucasian populations
-
Reviriego, J., Bertilsson, L., Carrillo, J. A., Llerena, A., Valdivielso, M. J. and Benitez, J.: Frequency of S-mephenytoin hydroxylation deficiency in 373 Spanish subjects compared to other Caucasian populations. Eur. J. Clin. Pharmacol., 44: 593-595 (1993).
-
(1993)
Eur. J. Clin. Pharmacol.
, vol.44
, pp. 593-595
-
-
Reviriego, J.1
Bertilsson, L.2
Carrillo, J.A.3
Llerena, A.4
Valdivielso, M.J.5
Benitez, J.6
-
200
-
-
0029018767
-
The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study
-
Balian, J. D., Sukhova, N., Harris, J. W., Hewett, J., Pickle, R. N. L., Goldstein, J. A., Woosley, R. L. and Flockhart, D. A.: The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study. Clin. Pharmacol. Ther., 57: 662-669 (1995).
-
(1995)
Clin. Pharmacol. Ther.
, vol.57
, pp. 662-669
-
-
Balian, J.D.1
Sukhova, N.2
Harris, J.W.3
Hewett, J.4
Pickle, R.N.L.5
Goldstein, J.A.6
Woosley, R.L.7
Flockhart, D.A.8
-
201
-
-
0019140947
-
A study of the debrisoquine hydroxylation polymorphism in a Nigerian population
-
Mbanefo, C., Bababunmi, E. A., Mahgoub, A., Sloan, T. P., Idle, J. R. and Smith, R. L.: A study of the debrisoquine hydroxylation polymorphism in a Nigerian population. Xenobiotica, 10: 811-888 (1980).
-
(1980)
Xenobiotica
, vol.10
, pp. 811-888
-
-
Mbanefo, C.1
Bababunmi, E.A.2
Mahgoub, A.3
Sloan, T.P.4
Idle, J.R.5
Smith, R.L.6
-
202
-
-
0026849692
-
Evidence for a dissociation in the control of sparteine, debrisoquine and metoprolol metabolism in Nigerians
-
Lennard, M. S., Iyun, A. O., Jackson, P. R., Tucker, G. T. and Woods, H. F.: Evidence for a dissociation in the control of sparteine, debrisoquine and metoprolol metabolism in Nigerians. Pharmacogenetics, 2: 89-92 (1992).
-
(1992)
Pharmacogenetics
, vol.2
, pp. 89-92
-
-
Lennard, M.S.1
Iyun, A.O.2
Jackson, P.R.3
Tucker, G.T.4
Woods, H.F.5
-
203
-
-
84973847615
-
Polymorphism of the 4-hydroxylation of debrisoquine in the San Bushmen of South Africa
-
Sommers, D. K., Moncrieff, J. and Avenant, J. C.: Polymorphism of the 4-hydroxylation of debrisoquine in the San Bushmen of South Africa. Hum. Toxicol., 7: 273-276 (1988).
-
(1988)
Hum. Toxicol.
, vol.7
, pp. 273-276
-
-
Sommers, D.K.1
Moncrieff, J.2
Avenant, J.C.3
-
204
-
-
0018403260
-
A population and familial study of the defective alicyclic hydroxylation of debrisoquine among Egyptians
-
Mahgoub, A., Idle, J. R. and Smith, R. L.: A population and familial study of the defective alicyclic hydroxylation of debrisoquine among Egyptians. Xenobiotica, 9: 51-56 (1979).
-
(1979)
Xenobiotica
, vol.9
, pp. 51-56
-
-
Mahgoub, A.1
Idle, J.R.2
Smith, R.L.3
-
205
-
-
84965949194
-
Non-correlation between debrisoquine and metoprolol polymorphisms in the Venda
-
Sommers, D. K., Moncrieff, J. and Avenant, J. C.: Non-correlation between debrisoquine and metoprolol polymorphisms in the Venda. Hum. Toxicol., 8: 365-368 (1989).
-
(1989)
Hum. Toxicol.
, vol.8
, pp. 365-368
-
-
Sommers, D.K.1
Moncrieff, J.2
Avenant, J.C.3
-
206
-
-
0033429268
-
Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype
-
Wennerholm, A., Johansson, I., Massele, A. Y., Jande, M., Alm, C., Aden-Abdi, Y., Dahl, M.-L., Ingelman-Sundberg, M., Bertilsson, L. and Gustafsson, L. L.: Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype. Pharmacogenetics, 9: 707-714 (1999).
-
(1999)
Pharmacogenetics
, vol.9
, pp. 707-714
-
-
Wennerholm, A.1
Johansson, I.2
Massele, A.Y.3
Jande, M.4
Alm, C.5
Aden-Abdi, Y.6
Dahl, M.-L.7
Ingelman-Sundberg, M.8
Bertilsson, L.9
Gustafsson, L.L.10
-
207
-
-
0027248189
-
Debrisoquine and metoprolol oxidation in Zambians; a population study
-
Simooya, O. O., Njunju, E., Hodjegan, A. R., Lennard, M. S. and Tucker, G. T.: Debrisoquine and metoprolol oxidation in Zambians; a population study.Pharmacogenetics, 3: 205-208 (1993).
-
(1993)
Pharmacogenetics
, vol.3
, pp. 205-208
-
-
Simooya, O.O.1
Njunju, E.2
Hodjegan, A.R.3
Lennard, M.S.4
Tucker, G.T.5
-
208
-
-
3042932565
-
Polymorphism in sparteine oxidation in the Barakwena (Kwengo) of Southern Africa
-
Sommers, D. K., Moncrieff, J. and Avenant, J.: Polymorphism in sparteine oxidation in the Barakwena (Kwengo) of Southern Africa. South African J. Sci., 86: 28-29 (1990).
-
(1990)
South African J. Sci.
, vol.86
, pp. 28-29
-
-
Sommers, D.K.1
Moncrieff, J.2
Avenant, J.3
-
209
-
-
0029757159
-
Sparteine metabolism in a Nigerian population
-
Ritchie, J. C., Mitchell, S. C. and Smith, R. L.: Sparteine metabolism in a Nigerian population. Drug Metabol. Drug Interact., 13: 129-135 (1996).
-
(1996)
Drug Metabol. Drug Interact.
, vol.13
, pp. 129-135
-
-
Ritchie, J.C.1
Mitchell, S.C.2
Smith, R.L.3
-
210
-
-
0025848319
-
Absence of polymorphism of sparteine oxidation in the South African Venda
-
Sommers, D. K., Moncrieff, J. and Avenant, J. C.: Absence of polymorphism of sparteine oxidation in the South African Venda. Hum. Exp. Toxicol., 10: 175-178 (1991).
-
(1991)
Hum. Exp. Toxicol.
, vol.10
, pp. 175-178
-
-
Sommers, D.K.1
Moncrieff, J.2
Avenant, J.C.3
-
211
-
-
0025883603
-
Oxidative polymorphism of dextromethorphan in a Burundi population
-
Nsabiyumva, F., Furet, Y., Autret, E., Jonville, A. P. and Breteau, M.: Oxidative polymorphism of dextromethorphan in a Burundi population. Eur. J. Clin. Pharmacol., 41: 75-77 (1991).
-
(1991)
Eur. J. Clin. Pharmacol.
, vol.41
, pp. 75-77
-
-
Nsabiyumva, F.1
Furet, Y.2
Autret, E.3
Jonville, A.P.4
Breteau, M.5
-
212
-
-
0032922093
-
CYP2D6 polymorphism in a Gabonese population: contribution of the CYP2D6*2 and CYP2D6*17 alleles to the high prevalence of the intermediate metabolic phenotype
-
Panserat, S., Sica, L., Gerard, N., Jacqz-Aigrain, E. and Krishnamoorthy, R.: CYP2D6 polymorphism in a Gabonese population: contribution of the CYP2D6*2 and CYP2D6*17 alleles to the high prevalence of the intermediate metabolic phenotype. Br. J. Clin. Pharmacol., 47: 121-124 (1999).
-
(1999)
Br. J. Clin. Pharmacol.
, vol.47
, pp. 121-124
-
-
Panserat, S.1
Sica, L.2
Gerard, N.3
Jacqz-Aigrain, E.4
Krishnamoorthy, R.5
-
213
-
-
0028934224
-
Dextromethorphan polymorphic hepatic oxidation (CYP2Din healthy black American adult subjects
-
Marinac, J. S., Foxworth, J. W. and Willsie, S. K.: Dextromethorphan polymorphic hepatic oxidation (CYP2Din healthy black American adult subjects. Ther. Drug Monit., 17: 120-124 (1995).
-
(1995)
Ther. Drug Monit.
, vol.17
, pp. 120-124
-
-
Marinac, J.S.1
Foxworth, J.W.2
Willsie, S.K.3
-
214
-
-
84973816037
-
Metoprolol a-hydroxylation polymorphism in the San Bushmen of Southern Africa
-
Sommers, D. K., Moncrieff, J. and Avenant, J. C.: Metoprolol a-hydroxylation polymorphism in the San Bushmen of Southern Africa. Hum. Toxicol., 8: 39-43 (1989).
-
(1989)
Hum. Toxicol.
, vol.8
, pp. 39-43
-
-
Sommers, D.K.1
Moncrieff, J.2
Avenant, J.C.3
-
215
-
-
0029960882
-
Chloroguanide metabolism in relation to the effiency in malaria prophylaxis and the S-mephenytoin oxidation in Tanzanians
-
Skjelbo, E., Mutabingwa, T. K., Bygbjerg, I., Nielsen, K. K., Gram, L. F. and Brosen, K.: Chloroguanide metabolism in relation to the effiency in malaria prophylaxis and the S-mephenytoin oxidation in Tanzanians. Clin. Pharmacol. Ther., 59: 304-311 (1996).
-
(1996)
Clin. Pharmacol. Ther.
, vol.59
, pp. 304-311
-
-
Skjelbo, E.1
Mutabingwa, T.K.2
Bygbjerg, I.3
Nielsen, K.K.4
Gram, L.F.5
Brosen, K.6
-
216
-
-
4243834558
-
The 4-hydroxylation of (S)-mephenytoin in Nigerians: a population study. [(Abstract)]
-
Iyun, A. O., Tucker, G. T., Woods, H. F. and Lennard, M. S.: The 4-hydroxylation of (S)-mephenytoin in Nigerians: a population study. [(Abstract)]. Br. J. Clin. Pharmacol., 30: 312 P (1990).
-
(1990)
Br. J. Clin. Pharmacol.
, vol.30
, pp. 312
-
-
Iyun, A.O.1
Tucker, G.T.2
Woods, H.F.3
Lennard, M.S.4
-
217
-
-
0033909912
-
Similarities and/or dissimilarities of CYP2D6 polymorphism in three Tunisian ethnic groups: Arabs, Berbers, Numides
-
Attitallah, S., Berard, M., Belkahia, C., Bechtel, Y.C. and Bechtel, P.R.: Similarities and/or dissimilarities of CYP2D6 polymorphism in three Tunisian ethnic groups: Arabs, Berbers, Numides. Therapie, 55: 355-360 (2000).
-
(2000)
Therapie
, vol.55
, pp. 355-360
-
-
Attitallah, S.1
Berard, M.2
Belkahia, C.3
Bechtel, Y.C.4
Bechtel, P.R.5
-
218
-
-
0019137788
-
The polymorphic 4-hydroxylation of debrisoquine in a Saudi Arab population
-
Islam, S. I., Idle, J. R. and Smith, R. L.: The polymorphic 4-hydroxylation of debrisoquine in a Saudi Arab population. Xenobiotica, 10: 819-825 (1980).
-
(1980)
Xenobiotica
, vol.10
, pp. 819-825
-
-
Islam, S.I.1
Idle, J.R.2
Smith, R.L.3
-
219
-
-
0026254546
-
Polymorphic 4-hydroxylation of debrisoquine in a Turkish population
-
Sardas, S. Pontin, J. and Idle, J. R.: Polymorphic 4-hydroxylation of debrisoquine in a Turkish population. Pharmacogenetics, 1: 123-124 (1991).
-
(1991)
Pharmacogenetics
, vol.1
, pp. 123-124
-
-
Sardas, S.1
Pontin, J.2
Idle, J.R.3
-
220
-
-
0028238118
-
Polymorphic debrisoquin metabolism in a Turkish population
-
Bozkurt, A., Basci, N. E., Isimer, A., Sayal, A. and Kayaalp, S. O.: Polymorphic debrisoquin metabolism in a Turkish population. Clin. Pharmacol. Ther., 55: 399-401 (1994).
-
(1994)
Clin. Pharmacol. Ther.
, vol.55
, pp. 399-401
-
-
Bozkurt, A.1
Basci, N.E.2
Isimer, A.3
Sayal, A.4
Kayaalp, S.O.5
-
221
-
-
0027364755
-
Dextromethorphan O-demethylation polymorphism in Jordanians
-
Irshaid, Y. M., Al-Hadidi, H. F. and Rawashdeh, N. M.: Dextromethorphan O-demethylation polymorphism in Jordanians. Eur. J. Clin. Pharmacol., 45: 271-273 (1993).
-
(1993)
Eur. J. Clin. Pharmacol.
, vol.45
, pp. 271-273
-
-
Irshaid, Y.M.1
Al-Hadidi, H.F.2
Rawashdeh, N.M.3
-
222
-
-
0028104234
-
Metoprolol a-hydroxylation is a poor probe for debrisoquine oxidation (CYP2Dpolymorphism in Jordanians
-
Al-Hadidi, H. F., Irshaid, Y. M. and Rawashdeh, N. M.: Metoprolol a-hydroxylation is a poor probe for debrisoquine oxidation (CYP2Dpolymorphism in Jordanians. Eur. J. Clin. Pharmacol., 47: 311-314 (1994).
-
(1994)
Eur. J. Clin. Pharmacol.
, vol.47
, pp. 311-314
-
-
Al-Hadidi, H.F.1
Irshaid, Y.M.2
Rawashdeh, N.M.3
-
223
-
-
0028892079
-
S-mephenytoin hydroxylation phenotypes in a Jordanian population
-
Hadidi, H. F., Irshaid, Y. M., Woosey, R. L., Idle, J. R. and Flockhart, D. A.: S-mephenytoin hydroxylation phenotypes in a Jordanian population. Clin. Pharmacol. Ther., 58: 542-547 (1995).
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 542-547
-
-
Hadidi, H.F.1
Irshaid, Y.M.2
Woosey, R.L.3
Idle, J.R.4
Flockhart, D.A.5
-
224
-
-
85045720809
-
Genetic polymorphism of drug metabolizing enzymes: New mutations in CYP2D6 and CYP2A6 genes in Japanese
-
Yokoi, T. and Kamataki, T.: Genetic polymorphism of drug metabolizing enzymes: New mutations in CYP2D6 and CYP2A6 genes in Japanese. Folia Pharmacol. Jpn., 112: 5-14 (1998).
-
(1998)
Folia Pharmacol. Jpn.
, vol.112
, pp. 5-14
-
-
Yokoi, T.1
Kamataki, T.2
|