메뉴 건너뛰기




Volumn 65, Issue 5, 1999, Pages 570-575

Analysis of the CΥP2D6 gene in relation to dextromethorphan O- demethylation capacity in a Japanese population

Author keywords

[No Author keywords available]

Indexed keywords

DEBRISOQUINE 4 HYDROXYLASE; DEXTROMETHORPHAN; LEVALLORPHAN; O DEMETHYLASE; CYTOCHROME P450; CYTOCHROME P450 2D6; DEXTROMETHORPHAN O DEMETHYLASE; DEXTROMETHORPHAN O-DEMETHYLASE;

EID: 0032586732     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(99)70077-9     Document Type: Article
Times cited : (124)

References (24)
  • 1
    • 0026031652 scopus 로고
    • Interethnic variation of drug metabolism
    • 1. Werner K. Interethnic variation of drug metabolism. Trends Pharmacol Sci 1991;12:102-7.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 102-107
    • Werner, K.1
  • 2
    • 0029028932 scopus 로고
    • Geographical/interracial differences in polymorphic oxidation: Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19
    • 2. Bertilsson L. Geographical/interracial differences in polymorphic oxidation: current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet 1995;29:192-209.
    • (1995) Clin Pharmacokinet , vol.29 , pp. 192-209
    • Bertilsson, L.1
  • 3
    • 0002888510 scopus 로고
    • Human cytochrome P450 enzymes
    • Oritiz de Montellano PR, editor. New York: Plenum Press
    • 3. Guengerich FP. Human cytochrome P450 enzymes. In: Oritiz de Montellano PR, editor. Cytochrome P450. New York: Plenum Press; 1995. p. 473-535.
    • (1995) Cytochrome P450 , pp. 473-535
    • Guengerich, F.P.1
  • 4
    • 0025940815 scopus 로고
    • Molecular genetics of the debrisoquin-sparteine polymorphism
    • 4. Gonzalez FJ, Meyer UA. Molecular genetics of the debrisoquin-sparteine polymorphism. Clin Pharmacol Ther 1991;50:233-8.
    • (1991) Clin Pharmacol Ther , vol.50 , pp. 233-238
    • Gonzalez, F.J.1    Meyer, U.A.2
  • 6
    • 0025950370 scopus 로고
    • Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in a European population
    • 6. Broly F, Gaedik A, Helm M, Eichelbaum M, Morike K, Meyer UA. Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population. DNA Cell Biol 1991;10:545-8.
    • (1991) DNA Cell Biol , vol.10 , pp. 545-548
    • Broly, F.1    Gaedik, A.2    Helm, M.3    Eichelbaum, M.4    Morike, K.5    Meyer, U.A.6
  • 7
    • 0027276869 scopus 로고
    • Genetic basis for a lower prevalence of deficient CYP2D6 oxidative drug metabolism phenotypes in black Americans
    • 7. Evans WE, Relling MW, Rahman A, McLeod H, Scott E, Lin JS. Genetic basis for a lower prevalence of deficient CYP2D6 oxidative drug metabolism phenotypes in black Americans. J Clin Invest 1993;91:2150-4.
    • (1993) J Clin Invest , vol.91 , pp. 2150-2154
    • Evans, W.E.1    Relling, M.W.2    Rahman, A.3    McLeod, H.4    Scott, E.5    Lin, J.S.6
  • 8
    • 84920227522 scopus 로고
    • Low frequency of slow debrisoquine hydroxylation in a native Chinese population
    • 8. Lou YC, Ying L, Bertilsson L, Sjöqvist F. Low frequency of slow debrisoquine hydroxylation in a native Chinese population. Lancet 1987;2:852-3.
    • (1987) Lancet , vol.2 , pp. 852-853
    • Lou, Y.C.1    Ying, L.2    Bertilsson, L.3    Sjöqvist, F.4
  • 9
    • 0024262667 scopus 로고
    • Metoprolol oxidation in a japanese population: Evidence for only one poor metabolizer among 262 subjects
    • 9. Horai Y, Ishizaki T, Ishikawa K. Metoprolol oxidation in a Japanese population: evidence for only one poor metabolizer among 262 subjects. Br J Clin Pharmacol 1988; 26:807-8.
    • (1988) Br J Clin Pharmacol , vol.26 , pp. 807-808
    • Horai, Y.1    Ishizaki, T.2    Ishikawa, K.3
  • 10
    • 0029053644 scopus 로고
    • Genetic analysis of the CYP2D locus in relation to debrisoquine hydroxylation capacity in Korean, Japanese and Chinese subjects
    • 10. Dahl ML, Yue QY, Roh HK, Johansson I, Säwe J, Sjöqvist F, et al. Genetic analysis of the CYP2D locus in relation to debrisoquine hydroxylation capacity in Korean, Japanese and Chinese subjects. Pharmacogenetics 1995;5:159-64.
    • (1995) Pharmacogenetics , vol.5 , pp. 159-164
    • Dahl, M.L.1    Yue, Q.Y.2    Roh, H.K.3    Johansson, I.4    Säwe, J.5    Sjöqvist, F.6
  • 11
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 2D-locus as a cause of ultrarapid metabolism of debrisoquine
    • 11. Johansson I, Lundqvist E, Bertilsson L, Dahl ML, Sjöqvist F, Ingelman-Sundberg M. Inherited amplification of an active gene in the cytochrome P450 2D-locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 1993;90:11825-9.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 12
    • 0029064096 scopus 로고
    • Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis
    • 12. Dahl ML, Johansson L, Bertilsson L, Ingelman-Sundberg M, Sjöqvist F. Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis. J Pharmacol Exp Ther 1995;274:516-20.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 516-520
    • Dahl, M.L.1    Johansson, L.2    Bertilsson, L.3    Ingelman-Sundberg, M.4    Sjöqvist, F.5
  • 13
    • 0028942981 scopus 로고
    • Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
    • 13. Agúndez JAG, Ledesma MC, Ladero JM, Benitez J. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995;57:265-9.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 265-269
    • Agúndez, J.A.G.1    Ledesma, M.C.2    Ladero, J.M.3    Benitez, J.4
  • 14
    • 0030432585 scopus 로고    scopus 로고
    • Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiplicated functional CYP2D6 alleles
    • 14. Aklillu E, Persson I, Bertilsson L, Johansson I, Rodrigues F, Ingelman-Sundberg M. Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiplicated functional CYP2D6 alleles. J Pharmacol Exp Ther 1996;278:441-6.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 441-446
    • Aklillu, E.1    Persson, I.2    Bertilsson, L.3    Johansson, I.4    Rodrigues, F.5    Ingelman-Sundberg, M.6
  • 15
    • 0024442372 scopus 로고
    • Metoprolol and mephenytoin oxidation polymorphism in Far Eastern Oriental subjects: Japanese versus mainland Chinese
    • 15. Horai Y, Nakano M, Ishizaki T, Ishikawa K, Zhou HH, Zhou B J, et al. Metoprolol and mephenytoin oxidation polymorphism in Far Eastern Oriental subjects: Japanese versus mainland Chinese. Clin Pharmacol Ther 1989;46: 198-207.
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 198-207
    • Horai, Y.1    Nakano, M.2    Ishizaki, T.3    Ishikawa, K.4    Zhou, H.H.5    Zhou, B.J.6
  • 16
    • 0027418152 scopus 로고
    • Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6
    • 16. Wang SL, Huang JD, Lai MD, Liu BH, Lai ML. Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6. Clin Pharmacol Ther 1993;53:410-8.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 410-418
    • Wang, S.L.1    Huang, J.D.2    Lai, M.D.3    Liu, B.H.4    Lai, M.L.5
  • 17
    • 0022338958 scopus 로고
    • Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquine hydroxylation
    • 17. Schmid B, Bircher J, Preisig R, Küpfer A. Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquine hydroxylation. Clin Pharmacol Ther 1985;38:618-24.
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 618-624
    • Schmid, B.1    Bircher, J.2    Preisig, R.3    Küpfer, A.4
  • 18
    • 0030176243 scopus 로고    scopus 로고
    • High performance liquid chromatography determination of dextromethorphan and its metabolites in urine using solid-phase extraction
    • 18. Bartoletti RA, Belpaire FM, Rosseel MT. High performance liquid chromatography determination of dextromethorphan and its metabolites in urine using solid-phase extraction. J Pharm Biomed Anal 1996;14:1281-6.
    • (1996) J Pharm Biomed Anal , vol.14 , pp. 1281-1286
    • Bartoletti, R.A.1    Belpaire, F.M.2    Rosseel, M.T.3
  • 19
    • 10344266435 scopus 로고    scopus 로고
    • A new CYP2D6 allele with a nine base insertion in exon 9 in a Japanese population associated with poor metabolizer phenotype
    • 19. Yokoi T, Kosaka Y, Chida M, Chiba K, Nakamura H, Ishizaki T, et al. A new CYP2D6 allele with a nine base insertion in exon 9 in a Japanese population associated with poor metabolizer phenotype. Pharmacogenetics 1996;6:395-401.
    • (1996) Pharmacogenetics , vol.6 , pp. 395-401
    • Yokoi, T.1    Kosaka, Y.2    Chida, M.3    Chiba, K.4    Nakamura, H.5    Ishizaki, T.6
  • 20
    • 0025080352 scopus 로고
    • Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification
    • 20. Heim M, Meyer UA. Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification. Lancet 1990;336:529-32.
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.1    Meyer, U.A.2
  • 22
    • 0027965620 scopus 로고
    • Genetic analysis of the Chinese cytochrome P4502D locus: Characterization of variant CYP2D6 gene present in subjects with diminished capacity for debrisoquine hydroxylation
    • 22. Johansson I, Oscarson M, Yue QY, Bertilsson L, Sjöqvist F, Ingelman-Sundberg M. Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 gene present in subjects with diminished capacity for debrisoquine hydroxylation. Mol Pharmacol 1994;46:452-9.
    • (1994) Mol Pharmacol , vol.46 , pp. 452-459
    • Johansson, I.1    Oscarson, M.2    Yue, Q.Y.3    Bertilsson, L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 24
    • 0028358565 scopus 로고
    • The cytochrome P450 CYP2D6 allelic variant CYP2D6J and related polymorphism in a European population
    • 24. Armstrong M, Fairbrother K, Idle JR, Daly AK. The cytochrome P450 CYP2D6 allelic variant CYP2D6J and related polymorphism in a European population. Pharmacogenetics 1994;4:73-81.
    • (1994) Pharmacogenetics , vol.4 , pp. 73-81
    • Armstrong, M.1    Fairbrother, K.2    Idle, J.R.3    Daly, A.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.