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Volumn 66, Issue 2, 1999, Pages 185-192

Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

EID: 0032772078     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1053/cp.1999.v66.100072001     Document Type: Article
Times cited : (141)

References (41)
  • 1
    • 0030904031 scopus 로고    scopus 로고
    • Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations
    • 1. Goldstein JA, Ishizaki T, Chiba K, de Morais SM, Bell D, Krahn PM, et al. Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations. Pharmacogenetics 1997;7:59-64.
    • (1997) Pharmacogenetics , vol.7 , pp. 59-64
    • Goldstein, J.A.1    Ishizaki, T.2    Chiba, K.3    De Morais, S.M.4    Bell, D.5    Krahn, P.M.6
  • 3
    • 0030860004 scopus 로고    scopus 로고
    • Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution
    • 3. Marez D, Legrand M, Sabbagh N, Guidice JM, Spire C, Lafitte JJ, et al. Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics 1997;7:193-202.
    • (1997) Pharmacogenetics , vol.7 , pp. 193-202
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Guidice, J.M.4    Spire, C.5    Lafitte, J.J.6
  • 5
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • 5. Bertz RJ, Granneman GR. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 1997;32:210-58.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 6
    • 0021237993 scopus 로고
    • Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man
    • 6. Küpfer A, Preisig R. Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man. Eur J Clin Pharmacol 1984;26:753-9.
    • (1984) Eur J Clin Pharmacol , vol.26 , pp. 753-759
    • Küpfer, A.1    Preisig, R.2
  • 7
    • 0027445449 scopus 로고
    • Isolation and characterization of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylation
    • 7. Wrighton SA, Stevens JC, Becker GW, VandenBranden M. Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4′-hydroxylation. Arch Biochem Biophys 1993;306:240-5.
    • (1993) Arch Biochem Biophys , vol.306 , pp. 240-245
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, G.W.3    VandenBranden, M.4
  • 10
    • 0028044085 scopus 로고
    • Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese
    • 10. De Morais SM, Wilkinson GR, Blaisdell J, Meyer UA, Nakamura K, Goldstein JA. Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese. Mol Pharmacol 1994;46:594-8.
    • (1994) Mol Pharmacol , vol.46 , pp. 594-598
    • De Morais, S.M.1    Wilkinson, G.R.2    Blaisdell, J.3    Meyer, U.A.4    Nakamura, K.5    Goldstein, J.A.6
  • 11
    • 15444340367 scopus 로고    scopus 로고
    • A new genetic defect in human CYP2C19: Mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin
    • 11. Ferguson RJ, De Morais SM, Benhamou S, Bouchardy C, Blaisdell J, Ibeanu G, et al. A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin. J Pharmacol Exp Ther 1998;284:356-61.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 356-361
    • Ferguson, R.J.1    De Morais, S.M.2    Benhamou, S.3    Bouchardy, C.4    Blaisdell, J.5    Ibeanu, G.6
  • 12
    • 8244249473 scopus 로고    scopus 로고
    • Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele
    • 12. Xiao ZS, Goldstein JA, Xie HG, Blaisdell J, Wang W, Jiang CH, et al. Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele. J Pharmacol Exp Ther 1997;281:604-9.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 604-609
    • Xiao, Z.S.1    Goldstein, J.A.2    Xie, H.G.3    Blaisdell, J.4    Wang, W.5    Jiang, C.H.6
  • 13
    • 0022178173 scopus 로고
    • Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations
    • 13. Nakamura K, Goto F, Ray WA, McAllister CB, Jacqz E, Wilkinson GR, et al. Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations. Clin Pharmacol Ther 1985;38:402-8.
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 402-408
    • Nakamura, K.1    Goto, F.2    Ray, W.A.3    McAllister, C.B.4    Jacqz, E.5    Wilkinson, G.R.6
  • 14
    • 0024442372 scopus 로고
    • Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese
    • 14. Horai Y, Nakano M, Ishizaki T, Ishikawa K, Zhou HH, Zhou BI, et al. Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese. Clin Pharmacol Ther 1989; 46:198-207.
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 198-207
    • Horai, Y.1    Nakano, M.2    Ishizaki, T.3    Ishikawa, K.4    Zhou, H.H.5    Zhou, B.I.6
  • 15
    • 0026506140 scopus 로고
    • Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
    • 15. Bertilsson L, Lou YQ, Du YL, Liu Y, Kuang TY, Liao XM, et al. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin. Clin Pharmacol Ther 1992;51:388-97.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 388-397
    • Bertilsson, L.1    Lou, Y.Q.2    Du, Y.L.3    Liu, Y.4    Kuang, T.Y.5    Liao, X.M.6
  • 16
    • 0026705708 scopus 로고
    • Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics
    • 16. Sohn DR, Kusaka M, Ishizaki T, Shin SG, Jang IJ, Shin JG, et al. Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics. Clin Pharmacol Ther 1992;52:160-9.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 160-169
    • Sohn, D.R.1    Kusaka, M.2    Ishizaki, T.3    Shin, S.G.4    Jang, I.J.5    Shin, J.G.6
  • 17
    • 0029042294 scopus 로고
    • The mephenytoin (cytochrome P450 2C19) and dextromethorphan (cytochrome P450 2D6) polymorphisms in Saudi Arabians and Filipinos
    • 17. Evans DA, Krahn P, Narayanan N. The mephenytoin (cytochrome P450 2C19) and dextromethorphan (cytochrome P450 2D6) polymorphisms in Saudi Arabians and Filipinos. Pharmacogenetics 1995;5:64-71.
    • (1995) Pharmacogenetics , vol.5 , pp. 64-71
    • Evans, D.A.1    Krahn, P.2    Narayanan, N.3
  • 18
    • 0028114838 scopus 로고
    • S-mephenytoin, sparteine and debrisoquine oxidation: Genetic polymorphisms in a Turkish population
    • 18. Basci NE, Brøsen K, Bozkurt A, Isimer A, Sayal A, Kayaalp SO. S-mephenytoin, sparteine and debrisoquine oxidation: genetic polymorphisms in a Turkish population. Br J Clin Pharmacol 1994;38:463-5.
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 463-465
    • Basci, N.E.1    Brøsen, K.2    Bozkurt, A.3    Isimer, A.4    Sayal, A.5    Kayaalp, S.O.6
  • 19
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
    • 19. Sachse C, Brockmöller J, Bauer S, Roots I. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet 1997;60:284-95.
    • (1997) Am J Hum Genet , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmöller, J.2    Bauer, S.3    Roots, I.4
  • 20
    • 0031960093 scopus 로고    scopus 로고
    • Correctness of prediction of the CYP2D6 phenotype confirmed by genotyping 47 intermediate and poor metabolizers of debrisoquine
    • 20. Sachse C, Brockmöller J, Hildebrand M, Müller K, Roots I. Correctness of prediction of the CYP2D6 phenotype confirmed by genotyping 47 intermediate and poor metabolizers of debrisoquine. Pharmacogenetics 1998;8:181-5.
    • (1998) Pharmacogenetics , vol.8 , pp. 181-185
    • Sachse, C.1    Brockmöller, J.2    Hildebrand, M.3    Müller, K.4    Roots, I.5
  • 22
    • 0024796958 scopus 로고
    • The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene
    • 22. Kimura S, Umeno M, Skoda RC, Meyer UA, Gonzalez FJ. The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. Am J Hum Genet 1989;45:889-904.
    • (1989) Am J Hum Genet , vol.45 , pp. 889-904
    • Kimura, S.1    Umeno, M.2    Skoda, R.C.3    Meyer, U.A.4    Gonzalez, F.J.5
  • 25
    • 13144258722 scopus 로고    scopus 로고
    • Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype
    • 25. Herrlin K, Massele AY, Jande M, Alm C, Tybring G, Abdi YA, et al. Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype. Clin Pharmacol Ther 1998;64:391-401.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 391-401
    • Herrlin, K.1    Massele, A.Y.2    Jande, M.3    Alm, C.4    Tybring, G.5    Abdi, Y.A.6
  • 27
    • 0027965620 scopus 로고
    • Genetic analysis of the Chinese cytochrome P4502D locus: Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation
    • 27. Johansson I, Oscarson M, Yue QY, Bertilsson L, Sjöqvist F, Ingelman-Sundberg M. Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation. Mol Pharmacol 1994;46:452-9.
    • (1994) Mol Pharmacol , vol.46 , pp. 452-459
    • Johansson, I.1    Oscarson, M.2    Yue, Q.Y.3    Bertilsson, L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 28
    • 0029064096 scopus 로고
    • Ultrarapid hydroxylation of debrisoquine in a Swedish population: Analysis of the molecular genetic basis
    • 28. Dahl ML, Johansson I, Bertilsson L, Ingelman-Sundberg M, Sjöqvist F. Ultrarapid hydroxylation of debrisoquine in a Swedish population: analysis of the molecular genetic basis. J Pharmacol Exp Ther 1995;274:516-20.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 516-520
    • Dahl, M.L.1    Johansson, I.2    Bertilsson, L.3    Ingelman-Sundberg, M.4    Sjöqvist, F.5
  • 29
    • 0031884233 scopus 로고    scopus 로고
    • Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population
    • 29. Griese EU, Zanger UM, Brudermanns U, Gaedigk A, Mikus G, Mörike K, et al. Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population. Pharmacogenetics 1998;8:15-26.
    • (1998) Pharmacogenetics , vol.8 , pp. 15-26
    • Griese, E.U.1    Zanger, U.M.2    Brudermanns, U.3    Gaedigk, A.4    Mikus, G.5    Mörike, K.6
  • 31
    • 0031408418 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County
    • 31. London SJ, Daly AK, Leathart JB, Navidi WC, Carpenter CC, Idle JR. Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County. Carcinogenesis 1997;18:1203-14.
    • (1997) Carcinogenesis , vol.18 , pp. 1203-1214
    • London, S.J.1    Daly, A.K.2    Leathart, J.B.3    Navidi, W.C.4    Carpenter, C.C.5    Idle, J.R.6
  • 32
    • 0030795692 scopus 로고    scopus 로고
    • Molecular heterogeneity at the CYP2D gene locus in Nicaraguans: Impact of gene-flow from Europe
    • 32. Agundez JA, Ramirez R, Hernandez M, Llerena A, Benitez J. Molecular heterogeneity at the CYP2D gene locus in Nicaraguans: impact of gene-flow from Europe. Pharmacogenetics 1997;7:337-40.
    • (1997) Pharmacogenetics , vol.7 , pp. 337-340
    • Agundez, J.A.1    Ramirez, R.2    Hernandez, M.3    Llerena, A.4    Benitez, J.5
  • 34
    • 0028942981 scopus 로고
    • Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
    • 34. Agundez JA, Ledesma MC, Ladero JM, Benitez J. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995;57:265-9.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 265-269
    • Agundez, J.A.1    Ledesma, M.C.2    Ladero, J.M.3    Benitez, J.4
  • 36
    • 0030432585 scopus 로고    scopus 로고
    • Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles
    • 36. Aklillu E, Persson I, Bertilsson L, Johansson I, Rodrigues F, Ingelman-Sundberg M. Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles. J Pharmacol Exp Ther 1996;278:441-6.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 441-446
    • Aklillu, E.1    Persson, I.2    Bertilsson, L.3    Johansson, I.4    Rodrigues, F.5    Ingelman-Sundberg, M.6
  • 37
    • 0031438162 scopus 로고    scopus 로고
    • A combination of mutations in the CYP2D6*17 (CYP2D6Z) allele causes alterations in enzyme function
    • 37. Oscarson M, Hidestrand M, Johansson I, Ingelman-Sundberg M. A combination of mutations in the CYP2D6*17 (CYP2D6Z) allele causes alterations in enzyme function. Mol Pharmacol 1997;52:1034-40.
    • (1997) Mol Pharmacol , vol.52 , pp. 1034-1040
    • Oscarson, M.1    Hidestrand, M.2    Johansson, I.3    Ingelman-Sundberg, M.4
  • 38
    • 0029853664 scopus 로고    scopus 로고
    • A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: Association with diminished debrisoquine hydroxylase activity
    • 38. Masimirembwa C, Persson I, Bertilsson L, Hasler J, Ingelman-Sundberg M. A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity. Br J Clin Pharmacol 1996; 42:713-9.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 713-719
    • Masimirembwa, C.1    Persson, I.2    Bertilsson, L.3    Hasler, J.4    Ingelman-Sundberg, M.5
  • 40
    • 0031456155 scopus 로고    scopus 로고
    • Characterization of a human glutathione S-transferase mu cluster containing a duplicated GSTM1 gene that causes ultrarapid enzyme activity
    • 40. McLellan RA, Oscarson M, Alexandrie AK, Seidegård J, Evans DA, Rannug A, et al. Characterization of a human glutathione S-transferase mu cluster containing a duplicated GSTM1 gene that causes ultrarapid enzyme activity. Mol Pharmacol 1997;52:958-65.
    • (1997) Mol Pharmacol , vol.52 , pp. 958-965
    • McLellan, R.A.1    Oscarson, M.2    Alexandrie, A.K.3    Seidegård, J.4    Evans, D.A.5    Rannug, A.6


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