-
1
-
-
0021323696
-
Etiology of Parkinson's disease: A research strategy
-
Barbeau A, Roy M. Etiology of Parkinson's disease: a research strategy. Can J Neurol Sci 1984;11:24-28.
-
(1984)
Can J Neurol Sci
, vol.11
, pp. 24-28
-
-
Barbeau, A.1
Roy, M.2
-
2
-
-
0022408175
-
Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
-
Barbeau A, Cloutier T, Roy M, Plasse L, Paris S, Poirier J. Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine. Lancet 1985;2:1213-1216.
-
(1985)
Lancet
, vol.2
, pp. 1213-1216
-
-
Barbeau, A.1
Cloutier, T.2
Roy, M.3
Plasse, L.4
Paris, S.5
Poirier, J.6
-
3
-
-
0018278763
-
Genetically determined defects of oxidation at carbon centres of drugs
-
Smith RL, Idle JR, Mahgoub AA, Sloan TP, Lancaster R. Genetically determined defects of oxidation at carbon centres of drugs [letter]. Lancet 1978;1:943-944.
-
(1978)
Lancet
, vol.1
, pp. 943-944
-
-
Smith, R.L.1
Idle, J.R.2
Mahgoub, A.A.3
Sloan, T.P.4
Lancaster, R.5
-
4
-
-
0022742309
-
Smoking, cancer, and Parkinson's disease
-
Barbeau A, Roy M, Cloutier RT. Smoking, cancer, and Parkinson's disease [letter]. Ann Neurol 1986;20:105-106.
-
(1986)
Ann Neurol
, vol.20
, pp. 105-106
-
-
Barbeau, A.1
Roy, M.2
Cloutier, R.T.3
-
5
-
-
0023279624
-
Debrisoquine metabolism in parkinsonian patients treated with antihistamine drugs
-
Poirier J, Roy M, Campanella G, Cloutier T, Paris S. Debrisoquine metabolism in parkinsonian patients treated with antihistamine drugs [letter]. Lancet 1987;2:386.
-
(1987)
Lancet
, vol.2
, pp. 386
-
-
Poirier, J.1
Roy, M.2
Campanella, G.3
Cloutier, T.4
Paris, S.5
-
6
-
-
0010506383
-
Debrisoquine metabolism in Parkinson's disease
-
Comella CL, Tanner CM, Goetz CG, Gans S, Rapp D, Fischer J. Debrisoquine metabolism in Parkinson's disease [abstract]. Neurology 1987;37(suppl 1):261-262.
-
(1987)
Neurology
, vol.37
, Issue.1 SUPPL.
, pp. 261-262
-
-
Comella, C.L.1
Tanner, C.M.2
Goetz, C.G.3
Gans, S.4
Rapp, D.5
Fischer, J.6
-
9
-
-
0025307264
-
Poor hydroxylator phenotypes of debrisoquine and S-mephenytoin are not overrepresented in a group of Parkinson's disease patients
-
Gudjonsson O, Sanz E, Alvan G, Aquilonius S-M, Reviriego J. Poor hydroxylator phenotypes of debrisoquine and S-mephenytoin are not overrepresented in a group of Parkinson's disease patients [letter]. Br J Clin Pharmacol 1990;30:301-302.
-
(1990)
Br J Clin Pharmacol
, vol.30
, pp. 301-302
-
-
Gudjonsson, O.1
Sanz, E.2
Alvan, G.3
Aquilonius, S.-M.4
Reviriego, J.5
-
10
-
-
0025284578
-
Etude de l'hydroxylation de la debrisoquine dans la maladie de Parkinson
-
Meillard MN, Bentue-Ferrer D, Brunet-Bourgin F, Morel G, Allain H. Etude de l'hydroxylation de la debrisoquine dans la maladie de Parkinson. Presse Med 1990;19:947-949.
-
(1990)
Presse Med
, vol.19
, pp. 947-949
-
-
Meillard, M.N.1
Bentue-Ferrer, D.2
Brunet-Bourgin, F.3
Morel, G.4
Allain, H.5
-
11
-
-
0026101719
-
Debrisoquine oxidation in Parkinson's disease
-
Kallio J, Marttila RJ, Rinne UK, Sonninen V, Syvalahti E. Debrisoquine oxidation in Parkinson's disease. Acta Neurol Scand 1991;83:194-197.
-
(1991)
Acta Neurol Scand
, vol.83
, pp. 194-197
-
-
Kallio, J.1
Marttila, R.J.2
Rinne, U.K.3
Sonninen, V.4
Syvalahti, E.5
-
12
-
-
0026781283
-
Debrisoquine hydroxylation in Parkinson's disease
-
Steiger MJ, Lledo P, Quinn NP, Marsden CD, Turner P, Jenner PC. Debrisoquine hydroxylation in Parkinson's disease. Acta Neurol Scand 1992;86:159-164.
-
(1992)
Acta Neurol Scand
, vol.86
, pp. 159-164
-
-
Steiger, M.J.1
Lledo, P.2
Quinn, N.P.3
Marsden, C.D.4
Turner, P.5
Jenner, P.C.6
-
14
-
-
0025080352
-
Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
-
Heim M, Meyer UA. Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet 1990; 336:529-532.
-
(1990)
Lancet
, vol.336
, pp. 529-532
-
-
Heim, M.1
Meyer, U.A.2
-
15
-
-
0026240125
-
Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes
-
Daly AK, Armstrong M, Monkman SC, Idle ME, Idle JR. Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes. Pharmacogenetics 1991;1:33-41.
-
(1991)
Pharmacogenetics
, vol.1
, pp. 33-41
-
-
Daly, A.K.1
Armstrong, M.2
Monkman, S.C.3
Idle, M.E.4
Idle, J.R.5
-
16
-
-
0022178173
-
Interethnic differences in genetic polymorphism of debrisoquin hydroxylation between Japanese and Caucasian populations
-
Nakamura K, Goto F, Ray WA, et al. Interethnic differences in genetic polymorphism of debrisoquin hydroxylation between Japanese and Caucasian populations. Clin Pharmacol Ther 1985;38:402-408.
-
(1985)
Clin Pharmacol Ther
, vol.38
, pp. 402-408
-
-
Nakamura, K.1
Goto, F.2
Ray, W.A.3
-
17
-
-
0022496369
-
Metoprolol and debrisoquin metabolism in Nigerians: Lack of evidence for polymorphic oxidation
-
Iyun AO, Lennard MS, Tucker GT, et al. Metoprolol and debrisoquin metabolism in Nigerians: lack of evidence for polymorphic oxidation. Clin Pharmacol Ther 1986;40:387-394.
-
(1986)
Clin Pharmacol Ther
, vol.40
, pp. 387-394
-
-
Iyun, A.O.1
Lennard, M.S.2
Tucker, G.T.3
-
18
-
-
84920227522
-
Low frequency of slow debrisoquine hydroxylation in a native Chinese population
-
Lou YC, Ying L, Bertilsson L, Sjoqvist F. Low frequency of slow debrisoquine hydroxylation in a native Chinese population [letter]. Lancet 1987;2:852-853.
-
(1987)
Lancet
, vol.2
, pp. 852-853
-
-
Lou, Y.C.1
Ying, L.2
Bertilsson, L.3
Sjoqvist, F.4
-
19
-
-
0023701452
-
Polymorphic debrisoquin hydroxylation in 757 Swedish subjects
-
Steiner E, Bertilsson L, Sawe J, Bertling I, Sjoquist F. Polymorphic debrisoquin hydroxylation in 757 Swedish subjects. Clin Pharmacol Ther 1988;44:431-435.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 431-435
-
-
Steiner, E.1
Bertilsson, L.2
Sawe, J.3
Bertling, I.4
Sjoquist, F.5
-
21
-
-
0025572192
-
Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations
-
Alvan G, Bechtel P, Iselius L, Gundert-Remy U. Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations. Eur J Clin Pharmacol 1990;39:533-537.
-
(1990)
Eur J Clin Pharmacol
, vol.39
, pp. 533-537
-
-
Alvan, G.1
Bechtel, P.2
Iselius, L.3
Gundert-Remy, U.4
-
22
-
-
0026589459
-
Mutant debrisoquine hydroxylase genes in Parkinson's disease
-
Armstrong M, Daly AK, Cholerton S, Bateman DN, Idle JR. Mutant debrisoquine hydroxylase genes in Parkinson's disease. Lancet 1992;339:1017-1018.
-
(1992)
Lancet
, vol.339
, pp. 1017-1018
-
-
Armstrong, M.1
Daly, A.K.2
Cholerton, S.3
Bateman, D.N.4
Idle, J.R.5
-
23
-
-
0026747176
-
Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease
-
Smith CAD, Gough AC, Leigh PN, et al. Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease. Lancet 1992;339:1375-1377.
-
(1992)
Lancet
, vol.339
, pp. 1375-1377
-
-
Smith, C.A.D.1
Gough, A.C.2
Leigh, P.N.3
-
24
-
-
0027330416
-
Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease
-
Kurth MC, Kurth JH. Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease. Am J Med Genet 1993;48:166-168.
-
(1993)
Am J Med Genet
, vol.48
, pp. 166-168
-
-
Kurth, M.C.1
Kurth, J.H.2
-
25
-
-
0013642531
-
Lack of association of CYP2D6 and Mao-B alleles with Parkinson's disease in a Kansas cohort
-
Kurth JH, Hubble JP, Eggers EA, Kurth MC, Koller WC, Lieberman AN. Lack of association of CYP2D6 and Mao-B alleles with Parkinson's disease in a Kansas cohort [abstract]. Neurology 1995;45(suppl 14):A429.
-
(1995)
Neurology
, vol.45
, Issue.14 SUPPL.
-
-
Kurth, J.H.1
Hubble, J.P.2
Eggers, E.A.3
Kurth, M.C.4
Koller, W.C.5
Lieberman, A.N.6
-
26
-
-
0028964602
-
Association between the oxidative polymorphism and early onset of Parkinson's disease
-
Agundez JA, Jimenez-Jimenez FJ, Luengo A, et al. Association between the oxidative polymorphism and early onset of Parkinson's disease. Clin Pharmacol Ther 1995;57:291-298.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 291-298
-
-
Agundez, J.A.1
Jimenez-Jimenez, F.J.2
Luengo, A.3
-
27
-
-
0001723185
-
Parkinson's disease
-
Gorelick PB, Alter M, eds. New York: Marcel Dekker
-
Tanner CM. Parkinson's disease. In: Gorelick PB, Alter M, eds. Handbook of neuroepidemiology. New York: Marcel Dekker, 1994:253-280.
-
(1994)
Handbook of Neuroepidemiology
, pp. 253-280
-
-
Tanner, C.M.1
-
28
-
-
0026515731
-
Core assessment program for intracerebral transplantations (CAPIT)
-
Langsten JW, Widner H, Goetz CG, et al. Core assessment program for intracerebral transplantations (CAPIT). Mov Disord 1992;7:2-13.
-
(1992)
Mov Disord
, vol.7
, pp. 2-13
-
-
Langsten, J.W.1
Widner, H.2
Goetz, C.G.3
-
29
-
-
0017148259
-
A general method for isolation of high molecular DNA from eukaryotes
-
Blin N, Stafford DW. A general method for isolation of high molecular DNA from eukaryotes. Nucleic Acids Res 1976;3: 2303-2308.
-
(1976)
Nucleic Acids Res
, vol.3
, pp. 2303-2308
-
-
Blin, N.1
Stafford, D.W.2
-
31
-
-
0023854270
-
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
-
Gonzalez FJ, Skoda RC, Kimura A, et al. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature 1988;331:442-446.
-
(1988)
Nature
, vol.331
, pp. 442-446
-
-
Gonzalez, F.J.1
Skoda, R.C.2
Kimura, A.3
-
32
-
-
0024796958
-
The human debrisoquine 4-hydroxylase (CYP2D6) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene and a pseudogene
-
Kimura S, Umeno M, Skoda RC, Meyer UA, Gonzalez FJ. The human debrisoquine 4-hydroxylase (CYP2D6) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene and a pseudogene. Am J Hum Genet 1989;45:889-905.
-
(1989)
Am J Hum Genet
, vol.45
, pp. 889-905
-
-
Kimura, S.1
Umeno, M.2
Skoda, R.C.3
Meyer, U.A.4
Gonzalez, F.J.5
-
33
-
-
0003525651
-
-
Centers for Disease Control, Atlanta, GA
-
Dean AG, Dean JA, Burton AH, Dicker RC. Epi Info, Version 6: a word processing, database, and statistics program for epidemiology on microcomputers. Centers for Disease Control, Atlanta, GA, 1990.
-
(1990)
Epi Info, Version 6: A Word Processing, Database, and Statistics Program for Epidemiology on Microcomputers
-
-
Dean, A.G.1
Dean, J.A.2
Burton, A.H.3
Dicker, R.C.4
-
34
-
-
84950756067
-
Computing an exact confidence interval for the common odds ratio in several 2 × 2 contingency tables
-
Mehta CR, Patel NR, Gray R. Computing an exact confidence interval for the common odds ratio in several 2 × 2 contingency tables. J Am Stat Assoc 1985;78:969-973.
-
(1985)
J Am Stat Assoc
, vol.78
, pp. 969-973
-
-
Mehta, C.R.1
Patel, N.R.2
Gray, R.3
-
35
-
-
0029102348
-
Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
-
Steen VM, Andreassen OA, Daly AK, et al. Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology. Pharmacogenetics 1995;5:215-223.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 215-223
-
-
Steen, V.M.1
Andreassen, O.A.2
Daly, A.K.3
-
36
-
-
0026608742
-
Epidemiology of Parkinson's disease
-
Tanner CM. Epidemiology of Parkinson's disease. Neurol Clin 1992;10:317-328.
-
(1992)
Neurol Clin
, vol.10
, pp. 317-328
-
-
Tanner, C.M.1
-
37
-
-
0023568113
-
MPTP, the neurotoxin inducing Parkinson's disease is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450 bufl, P450 db1) catalyzing debrisoquine 4-hydroxylation
-
Fonne-Pfister R, Bargetzi MJ, Meyer UA. MPTP, the neurotoxin inducing Parkinson's disease is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450 bufl, P450 db1) catalyzing debrisoquine 4-hydroxylation. Biochem Biophys Res Commun 1987;148:1144-1150.
-
(1987)
Biochem Biophys Res Commun
, vol.148
, pp. 1144-1150
-
-
Fonne-Pfister, R.1
Bargetzi, M.J.2
Meyer, U.A.3
-
38
-
-
0026515757
-
Contemporary issues in toxicology. Quinone chemistry and toxicology
-
Monks TJ, Hanzlik RP, Cohen GM, Ross D, Graham DG. Contemporary issues in toxicology. Quinone chemistry and toxicology. Toxicol Appl Pharmacol 1992;112:2-16.
-
(1992)
Toxicol Appl Pharmacol
, vol.112
, pp. 2-16
-
-
Monks, T.J.1
Hanzlik, R.P.2
Cohen, G.M.3
Ross, D.4
Graham, D.G.5
-
39
-
-
0028929652
-
An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution
-
Daly AK, Leathart JB, London SJ, Idle JR. An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution. Hum Genet 1995;95:337-341.
-
(1995)
Hum Genet
, vol.95
, pp. 337-341
-
-
Daly, A.K.1
Leathart, J.B.2
London, S.J.3
Idle, J.R.4
-
40
-
-
0028109283
-
A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine
-
Evert B, Griese EU, Eichelbaum M. A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine. Naunyn Schmiedebergs Arch Pharmacol 1994;350:434-439.
-
(1994)
Naunyn Schmiedebergs Arch Pharmacol
, vol.350
, pp. 434-439
-
-
Evert, B.1
Griese, E.U.2
Eichelbaum, M.3
-
41
-
-
0028305240
-
Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype
-
Saxena R, Shaw GL, Relling MV, et al. Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype. Hum Mol Genet 1994;3:923-926.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 923-926
-
-
Saxena, R.1
Shaw, G.L.2
Relling, M.V.3
-
42
-
-
0027989294
-
Debrisoquine hydroxylase gene polymorphism in familial Parkinson's disease
-
Plante-Bordeneuve V, Davis MB, Maraganore DM, Marsden CD, Harding AE. Debrisoquine hydroxylase gene polymorphism in familial Parkinson's disease. J Neurol Neurosurg Psychiatry 1994;57:911-913.
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 911-913
-
-
Plante-Bordeneuve, V.1
Davis, M.B.2
Maraganore, D.M.3
Marsden, C.D.4
Harding, A.E.5
-
43
-
-
0028124654
-
Genetic linkage studies in autosomal dominant parkinsonism: Evaluation of seven candidate genes
-
Gasser T, Wszolek ZK, Trofatter J, et al. Genetic linkage studies in autosomal dominant parkinsonism: evaluation of seven candidate genes. Ann Neurol 1994;36:387-396.
-
(1994)
Ann Neurol
, vol.36
, pp. 387-396
-
-
Gasser, T.1
Wszolek, Z.K.2
Trofatter, J.3
-
44
-
-
0028339524
-
Familial Parkinson's disease and polymorphism at the CYP2D6 locus
-
Mazzetti P, Le Guern E, Bonnet AM, Vidailhet M, Brice A, Agid Y. Familial Parkinson's disease and polymorphism at the CYP2D6 locus [letter]. J Neurol Neurosurg Psychiatry 1994; 57:871-872.
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 871-872
-
-
Mazzetti, P.1
Le Guern, E.2
Bonnet, A.M.3
Vidailhet, M.4
Brice, A.5
Agid, Y.6
-
45
-
-
0028090414
-
Genetic dissection of complex traits
-
Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994;265:2037-2048.
-
(1994)
Science
, vol.265
, pp. 2037-2048
-
-
Lander, E.S.1
Schork, N.J.2
-
46
-
-
0025938214
-
Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose
-
Nakachi K, Imai K, Hayashi S, Watanabe J, Kawajiri K. Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res 1991;51:5177-5180.
-
(1991)
Cancer Res
, vol.51
, pp. 5177-5180
-
-
Nakachi, K.1
Imai, K.2
Hayashi, S.3
Watanabe, J.4
Kawajiri, K.5
-
47
-
-
0027200680
-
A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease
-
Tsuneoka Y, Matsuo Y, Iwahashi K, Takeuchi H, Ichikawa Y. A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease. J Biochem 1993;114:263-266.
-
(1993)
J Biochem
, vol.114
, pp. 263-266
-
-
Tsuneoka, Y.1
Matsuo, Y.2
Iwahashi, K.3
Takeuchi, H.4
Ichikawa, Y.5
-
48
-
-
0027172453
-
A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by polymerase chain reaction
-
Armstrong M, Idle JR, Daly AK. A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by polymerase chain reaction. Hum Genet 1993;91:616-617.
-
(1993)
Hum Genet
, vol.91
, pp. 616-617
-
-
Armstrong, M.1
Idle, J.R.2
Daly, A.K.3
-
49
-
-
0027482068
-
DNA haplotype dependency of debrisoquine 4-hydroxylase (CYP2D6) expression among extensive metabolizers
-
Mura C, Panserat S, Vincent-Viry M, Galteau MM, Jacqz-Aigrain E, Krishnamoorthy R. DNA haplotype dependency of debrisoquine 4-hydroxylase (CYP2D6) expression among extensive metabolizers. Hum Genet 1993;92:367-372.
-
(1993)
Hum Genet
, vol.92
, pp. 367-372
-
-
Mura, C.1
Panserat, S.2
Vincent-Viry, M.3
Galteau, M.M.4
Jacqz-Aigrain, E.5
Krishnamoorthy, R.6
-
50
-
-
0027968799
-
DNA haplotype-dependent differences in the amino acid sequence of debrisoquine 4-hydroxylase (CYP2D6): Evidence for two major allozymes in extensive metabolisers
-
Panserat S, Mura C, Gérard N, et al. DNA haplotype-dependent differences in the amino acid sequence of debrisoquine 4-hydroxylase (CYP2D6): evidence for two major allozymes in extensive metabolisers. Hum Genet 1994;94:401-406.
-
(1994)
Hum Genet
, vol.94
, pp. 401-406
-
-
Panserat, S.1
Mura, C.2
Gérard, N.3
-
51
-
-
0027136288
-
Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
-
Johansson I, Lundqvist E, Bertilsson L, Dahl M-L, Sjöqvist F, Ingelman-Sundberg M. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 1993;90:11825-11829.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11825-11829
-
-
Johansson, I.1
Lundqvist, E.2
Bertilsson, L.3
Dahl, M.-L.4
Sjöqvist, F.5
Ingelman-Sundberg, M.6
|