메뉴 건너뛰기




Volumn 47, Issue 1, 1996, Pages 225-230

CYP2D6 allelic frequencies in young-onset Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE CLASSIFICATION; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; ONSET AGE; PARKINSON DISEASE; PRIORITY JOURNAL; RISK FACTOR;

EID: 0030056697     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.47.1.225     Document Type: Article
Times cited : (41)

References (51)
  • 1
    • 0021323696 scopus 로고
    • Etiology of Parkinson's disease: A research strategy
    • Barbeau A, Roy M. Etiology of Parkinson's disease: a research strategy. Can J Neurol Sci 1984;11:24-28.
    • (1984) Can J Neurol Sci , vol.11 , pp. 24-28
    • Barbeau, A.1    Roy, M.2
  • 2
    • 0022408175 scopus 로고
    • Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
    • Barbeau A, Cloutier T, Roy M, Plasse L, Paris S, Poirier J. Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine. Lancet 1985;2:1213-1216.
    • (1985) Lancet , vol.2 , pp. 1213-1216
    • Barbeau, A.1    Cloutier, T.2    Roy, M.3    Plasse, L.4    Paris, S.5    Poirier, J.6
  • 3
    • 0018278763 scopus 로고
    • Genetically determined defects of oxidation at carbon centres of drugs
    • Smith RL, Idle JR, Mahgoub AA, Sloan TP, Lancaster R. Genetically determined defects of oxidation at carbon centres of drugs [letter]. Lancet 1978;1:943-944.
    • (1978) Lancet , vol.1 , pp. 943-944
    • Smith, R.L.1    Idle, J.R.2    Mahgoub, A.A.3    Sloan, T.P.4    Lancaster, R.5
  • 4
    • 0022742309 scopus 로고
    • Smoking, cancer, and Parkinson's disease
    • Barbeau A, Roy M, Cloutier RT. Smoking, cancer, and Parkinson's disease [letter]. Ann Neurol 1986;20:105-106.
    • (1986) Ann Neurol , vol.20 , pp. 105-106
    • Barbeau, A.1    Roy, M.2    Cloutier, R.T.3
  • 5
    • 0023279624 scopus 로고
    • Debrisoquine metabolism in parkinsonian patients treated with antihistamine drugs
    • Poirier J, Roy M, Campanella G, Cloutier T, Paris S. Debrisoquine metabolism in parkinsonian patients treated with antihistamine drugs [letter]. Lancet 1987;2:386.
    • (1987) Lancet , vol.2 , pp. 386
    • Poirier, J.1    Roy, M.2    Campanella, G.3    Cloutier, T.4    Paris, S.5
  • 9
    • 0025307264 scopus 로고
    • Poor hydroxylator phenotypes of debrisoquine and S-mephenytoin are not overrepresented in a group of Parkinson's disease patients
    • Gudjonsson O, Sanz E, Alvan G, Aquilonius S-M, Reviriego J. Poor hydroxylator phenotypes of debrisoquine and S-mephenytoin are not overrepresented in a group of Parkinson's disease patients [letter]. Br J Clin Pharmacol 1990;30:301-302.
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 301-302
    • Gudjonsson, O.1    Sanz, E.2    Alvan, G.3    Aquilonius, S.-M.4    Reviriego, J.5
  • 14
    • 0025080352 scopus 로고
    • Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
    • Heim M, Meyer UA. Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet 1990; 336:529-532.
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.1    Meyer, U.A.2
  • 15
    • 0026240125 scopus 로고
    • Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes
    • Daly AK, Armstrong M, Monkman SC, Idle ME, Idle JR. Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes. Pharmacogenetics 1991;1:33-41.
    • (1991) Pharmacogenetics , vol.1 , pp. 33-41
    • Daly, A.K.1    Armstrong, M.2    Monkman, S.C.3    Idle, M.E.4    Idle, J.R.5
  • 16
    • 0022178173 scopus 로고
    • Interethnic differences in genetic polymorphism of debrisoquin hydroxylation between Japanese and Caucasian populations
    • Nakamura K, Goto F, Ray WA, et al. Interethnic differences in genetic polymorphism of debrisoquin hydroxylation between Japanese and Caucasian populations. Clin Pharmacol Ther 1985;38:402-408.
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 402-408
    • Nakamura, K.1    Goto, F.2    Ray, W.A.3
  • 17
    • 0022496369 scopus 로고
    • Metoprolol and debrisoquin metabolism in Nigerians: Lack of evidence for polymorphic oxidation
    • Iyun AO, Lennard MS, Tucker GT, et al. Metoprolol and debrisoquin metabolism in Nigerians: lack of evidence for polymorphic oxidation. Clin Pharmacol Ther 1986;40:387-394.
    • (1986) Clin Pharmacol Ther , vol.40 , pp. 387-394
    • Iyun, A.O.1    Lennard, M.S.2    Tucker, G.T.3
  • 18
    • 84920227522 scopus 로고
    • Low frequency of slow debrisoquine hydroxylation in a native Chinese population
    • Lou YC, Ying L, Bertilsson L, Sjoqvist F. Low frequency of slow debrisoquine hydroxylation in a native Chinese population [letter]. Lancet 1987;2:852-853.
    • (1987) Lancet , vol.2 , pp. 852-853
    • Lou, Y.C.1    Ying, L.2    Bertilsson, L.3    Sjoqvist, F.4
  • 20
    • 0025291440 scopus 로고
    • Lung cancer and the debrisoquine metabolic phenotype
    • Caporaso NE, Tucker MA, Hoover RN, et al. Lung cancer and the debrisoquine metabolic phenotype. J Natl Cancer Inst 1990;82:1264-1272.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1264-1272
    • Caporaso, N.E.1    Tucker, M.A.2    Hoover, R.N.3
  • 21
    • 0025572192 scopus 로고
    • Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations
    • Alvan G, Bechtel P, Iselius L, Gundert-Remy U. Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations. Eur J Clin Pharmacol 1990;39:533-537.
    • (1990) Eur J Clin Pharmacol , vol.39 , pp. 533-537
    • Alvan, G.1    Bechtel, P.2    Iselius, L.3    Gundert-Remy, U.4
  • 23
    • 0026747176 scopus 로고
    • Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease
    • Smith CAD, Gough AC, Leigh PN, et al. Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease. Lancet 1992;339:1375-1377.
    • (1992) Lancet , vol.339 , pp. 1375-1377
    • Smith, C.A.D.1    Gough, A.C.2    Leigh, P.N.3
  • 24
    • 0027330416 scopus 로고
    • Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease
    • Kurth MC, Kurth JH. Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease. Am J Med Genet 1993;48:166-168.
    • (1993) Am J Med Genet , vol.48 , pp. 166-168
    • Kurth, M.C.1    Kurth, J.H.2
  • 25
    • 0013642531 scopus 로고
    • Lack of association of CYP2D6 and Mao-B alleles with Parkinson's disease in a Kansas cohort
    • Kurth JH, Hubble JP, Eggers EA, Kurth MC, Koller WC, Lieberman AN. Lack of association of CYP2D6 and Mao-B alleles with Parkinson's disease in a Kansas cohort [abstract]. Neurology 1995;45(suppl 14):A429.
    • (1995) Neurology , vol.45 , Issue.14 SUPPL.
    • Kurth, J.H.1    Hubble, J.P.2    Eggers, E.A.3    Kurth, M.C.4    Koller, W.C.5    Lieberman, A.N.6
  • 26
    • 0028964602 scopus 로고
    • Association between the oxidative polymorphism and early onset of Parkinson's disease
    • Agundez JA, Jimenez-Jimenez FJ, Luengo A, et al. Association between the oxidative polymorphism and early onset of Parkinson's disease. Clin Pharmacol Ther 1995;57:291-298.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 291-298
    • Agundez, J.A.1    Jimenez-Jimenez, F.J.2    Luengo, A.3
  • 27
    • 0001723185 scopus 로고
    • Parkinson's disease
    • Gorelick PB, Alter M, eds. New York: Marcel Dekker
    • Tanner CM. Parkinson's disease. In: Gorelick PB, Alter M, eds. Handbook of neuroepidemiology. New York: Marcel Dekker, 1994:253-280.
    • (1994) Handbook of Neuroepidemiology , pp. 253-280
    • Tanner, C.M.1
  • 28
    • 0026515731 scopus 로고
    • Core assessment program for intracerebral transplantations (CAPIT)
    • Langsten JW, Widner H, Goetz CG, et al. Core assessment program for intracerebral transplantations (CAPIT). Mov Disord 1992;7:2-13.
    • (1992) Mov Disord , vol.7 , pp. 2-13
    • Langsten, J.W.1    Widner, H.2    Goetz, C.G.3
  • 29
    • 0017148259 scopus 로고
    • A general method for isolation of high molecular DNA from eukaryotes
    • Blin N, Stafford DW. A general method for isolation of high molecular DNA from eukaryotes. Nucleic Acids Res 1976;3: 2303-2308.
    • (1976) Nucleic Acids Res , vol.3 , pp. 2303-2308
    • Blin, N.1    Stafford, D.W.2
  • 31
    • 0023854270 scopus 로고
    • Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
    • Gonzalez FJ, Skoda RC, Kimura A, et al. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature 1988;331:442-446.
    • (1988) Nature , vol.331 , pp. 442-446
    • Gonzalez, F.J.1    Skoda, R.C.2    Kimura, A.3
  • 32
    • 0024796958 scopus 로고
    • The human debrisoquine 4-hydroxylase (CYP2D6) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene and a pseudogene
    • Kimura S, Umeno M, Skoda RC, Meyer UA, Gonzalez FJ. The human debrisoquine 4-hydroxylase (CYP2D6) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene and a pseudogene. Am J Hum Genet 1989;45:889-905.
    • (1989) Am J Hum Genet , vol.45 , pp. 889-905
    • Kimura, S.1    Umeno, M.2    Skoda, R.C.3    Meyer, U.A.4    Gonzalez, F.J.5
  • 34
    • 84950756067 scopus 로고
    • Computing an exact confidence interval for the common odds ratio in several 2 × 2 contingency tables
    • Mehta CR, Patel NR, Gray R. Computing an exact confidence interval for the common odds ratio in several 2 × 2 contingency tables. J Am Stat Assoc 1985;78:969-973.
    • (1985) J Am Stat Assoc , vol.78 , pp. 969-973
    • Mehta, C.R.1    Patel, N.R.2    Gray, R.3
  • 35
    • 0029102348 scopus 로고
    • Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
    • Steen VM, Andreassen OA, Daly AK, et al. Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology. Pharmacogenetics 1995;5:215-223.
    • (1995) Pharmacogenetics , vol.5 , pp. 215-223
    • Steen, V.M.1    Andreassen, O.A.2    Daly, A.K.3
  • 36
    • 0026608742 scopus 로고
    • Epidemiology of Parkinson's disease
    • Tanner CM. Epidemiology of Parkinson's disease. Neurol Clin 1992;10:317-328.
    • (1992) Neurol Clin , vol.10 , pp. 317-328
    • Tanner, C.M.1
  • 37
    • 0023568113 scopus 로고
    • MPTP, the neurotoxin inducing Parkinson's disease is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450 bufl, P450 db1) catalyzing debrisoquine 4-hydroxylation
    • Fonne-Pfister R, Bargetzi MJ, Meyer UA. MPTP, the neurotoxin inducing Parkinson's disease is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450 bufl, P450 db1) catalyzing debrisoquine 4-hydroxylation. Biochem Biophys Res Commun 1987;148:1144-1150.
    • (1987) Biochem Biophys Res Commun , vol.148 , pp. 1144-1150
    • Fonne-Pfister, R.1    Bargetzi, M.J.2    Meyer, U.A.3
  • 39
    • 0028929652 scopus 로고
    • An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution
    • Daly AK, Leathart JB, London SJ, Idle JR. An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution. Hum Genet 1995;95:337-341.
    • (1995) Hum Genet , vol.95 , pp. 337-341
    • Daly, A.K.1    Leathart, J.B.2    London, S.J.3    Idle, J.R.4
  • 40
    • 0028109283 scopus 로고
    • A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine
    • Evert B, Griese EU, Eichelbaum M. A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine. Naunyn Schmiedebergs Arch Pharmacol 1994;350:434-439.
    • (1994) Naunyn Schmiedebergs Arch Pharmacol , vol.350 , pp. 434-439
    • Evert, B.1    Griese, E.U.2    Eichelbaum, M.3
  • 41
    • 0028305240 scopus 로고
    • Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype
    • Saxena R, Shaw GL, Relling MV, et al. Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype. Hum Mol Genet 1994;3:923-926.
    • (1994) Hum Mol Genet , vol.3 , pp. 923-926
    • Saxena, R.1    Shaw, G.L.2    Relling, M.V.3
  • 43
    • 0028124654 scopus 로고
    • Genetic linkage studies in autosomal dominant parkinsonism: Evaluation of seven candidate genes
    • Gasser T, Wszolek ZK, Trofatter J, et al. Genetic linkage studies in autosomal dominant parkinsonism: evaluation of seven candidate genes. Ann Neurol 1994;36:387-396.
    • (1994) Ann Neurol , vol.36 , pp. 387-396
    • Gasser, T.1    Wszolek, Z.K.2    Trofatter, J.3
  • 45
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994;265:2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 46
    • 0025938214 scopus 로고
    • Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose
    • Nakachi K, Imai K, Hayashi S, Watanabe J, Kawajiri K. Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res 1991;51:5177-5180.
    • (1991) Cancer Res , vol.51 , pp. 5177-5180
    • Nakachi, K.1    Imai, K.2    Hayashi, S.3    Watanabe, J.4    Kawajiri, K.5
  • 47
    • 0027200680 scopus 로고
    • A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease
    • Tsuneoka Y, Matsuo Y, Iwahashi K, Takeuchi H, Ichikawa Y. A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease. J Biochem 1993;114:263-266.
    • (1993) J Biochem , vol.114 , pp. 263-266
    • Tsuneoka, Y.1    Matsuo, Y.2    Iwahashi, K.3    Takeuchi, H.4    Ichikawa, Y.5
  • 48
    • 0027172453 scopus 로고
    • A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by polymerase chain reaction
    • Armstrong M, Idle JR, Daly AK. A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by polymerase chain reaction. Hum Genet 1993;91:616-617.
    • (1993) Hum Genet , vol.91 , pp. 616-617
    • Armstrong, M.1    Idle, J.R.2    Daly, A.K.3
  • 50
    • 0027968799 scopus 로고
    • DNA haplotype-dependent differences in the amino acid sequence of debrisoquine 4-hydroxylase (CYP2D6): Evidence for two major allozymes in extensive metabolisers
    • Panserat S, Mura C, Gérard N, et al. DNA haplotype-dependent differences in the amino acid sequence of debrisoquine 4-hydroxylase (CYP2D6): evidence for two major allozymes in extensive metabolisers. Hum Genet 1994;94:401-406.
    • (1994) Hum Genet , vol.94 , pp. 401-406
    • Panserat, S.1    Mura, C.2    Gérard, N.3
  • 51
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I, Lundqvist E, Bertilsson L, Dahl M-L, Sjöqvist F, Ingelman-Sundberg M. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 1993;90:11825-11829.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.-L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.