Functionally active duplications of the CYP2D6 gene are more prevalent among larynx and lung cancer patients

Oncology

Volumn 61, Issue 1, 2001, Pages 59-63

  Agúndez, José A G ^a   Gallardo, Lourdes ^a   Ledesma, María C ^a   Lozano, Luis ^a   Rodriguez Lescure, Alvaro ^b   Pontes, José C ^c   Iglesias Moreno, María C ^c   Poch, Joaquin ^c   Ladero, José M ^c   Benítez, Julio ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO DE ELCHE   (Spain)

^c HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

CYP2D6; Larynx, cancer; Lung, cancer; Polymorphism

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOCHROME P450 2D6; DRUG METABOLIZING ENZYME; OPIATE DERIVATIVE; XENOBIOTIC AGENT;

ADULT; AGED; ARTICLE; CANCER PAIN; CANCER RISK; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; GENE DUPLICATION; GENE FREQUENCY; GENE FUNCTION; GENETIC ANALYSIS; HUMAN; KINETICS; LARYNX CARCINOMA; LUNG CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; XENOBIOTIC METABOLISM;

ADULT; AGED; ALLELES; ANALGESICS, OPIOID; ANTINEOPLASTIC AGENTS; CASE-CONTROL STUDIES; CYTOCHROME P-450 CYP2D6; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENES, DUPLICATE; HETEROZYGOTE; HUMANS; LARYNGEAL NEOPLASMS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PAIN; POLYMORPHISM, GENETIC; PREVALENCE; SMOKING;

EID: 17844400295     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000055354     Document Type: Article

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