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Volumn 57, Issue 15, 2016, Pages 6669-6682

Diabetic retinopathy: Battling the global epidemic

Author keywords

Blood retinal barrier; Diabetes mellitus; Diabetic retinopathy; Endothelial cells; Pericytes; Retina

Indexed keywords

AFLIBERCEPT; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; DNA METHYLTRANSFERASE; HEMOGLOBIN A1C; KALLIKREIN INHIBITOR; MICRORNA; PEGAPTANIB; RANIBIZUMAB; REACTIVE OXYGEN METABOLITE; SIRTUIN; STREPTOZOCIN; TRANSCRIPTION FACTOR NRF2; VASCULOTROPIN;

EID: 85006416156     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.16-21031     Document Type: Article
Times cited : (47)

References (86)
  • 1
    • 84978359538 scopus 로고    scopus 로고
    • International Diabetes Federation, 7th ed. Brussels, Belgium: International Diabetes Federation
    • International Diabetes Federation. IDF Diabetes Atlas. 7th ed. Brussels, Belgium: International Diabetes Federation; 2015.
    • (2015) IDF Diabetes Atlas
  • 2
    • 84859030420 scopus 로고    scopus 로고
    • Meta-Analysis for Eye Disease (META-EYE) Study Group. Global prevalence and risk factors of diabetic retinopathy
    • Yau JW, Rogers SL, Kawasaki R, et al.; Meta-Analysis for Eye Disease (META-EYE) Study Group. Global prevalence and risk factors of diabetic retinopathy. Diabetes Care. 2012;35:556-564.
    • (2012) Diabetes Care , vol.35 , pp. 556-564
    • Yau, J.W.1    Rogers, S.L.2    Kawasaki, R.3
  • 3
    • 76149134353 scopus 로고    scopus 로고
    • Lack of awareness amongst community patients with diabetes and diabetic retinopathy: The Singapore Malay Eye Study
    • Huang OS, Tay WT, Tai ES, et al. Lack of awareness amongst community patients with diabetes and diabetic retinopathy: the Singapore Malay Eye Study. Ann Acad Med Singapore. 2009;38:1048-1055.
    • (2009) Ann Acad Med Singapore , vol.38 , pp. 1048-1055
    • Huang, O.S.1    Tay, W.T.2    Tai, E.S.3
  • 4
    • 84962467336 scopus 로고    scopus 로고
    • Incidence of diabetes and prediabetes and predictors of progression among Asian Indians: 10-year follow-up of the Chennai Urban Rural Epidemiology Study (CURES)
    • Anjana RM, Shanthi Rani CS, Deepa M, et al. Incidence of diabetes and prediabetes and predictors of progression among Asian Indians: 10-year follow-up of the Chennai Urban Rural Epidemiology Study (CURES). Diabetes Care. 2015;38: 1441-1448.
    • (2015) Diabetes Care , vol.38 , pp. 1441-1448
    • Anjana, R.M.1    Shanthi Rani, C.S.2    Deepa, M.3
  • 5
    • 77955663714 scopus 로고    scopus 로고
    • Association of obesity with diabetic retinopathy: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study (SN-DREAMS Report no. 8)
    • Raman R, Rani PK, Gnanamoorthy P, et al. Association of obesity with diabetic retinopathy: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study (SN-DREAMS Report no. 8). Acta Diabetol. 2010;47:209-215.
    • (2010) Acta Diabetol , vol.47 , pp. 209-215
    • Raman, R.1    Rani, P.K.2    Gnanamoorthy, P.3
  • 6
    • 42449121829 scopus 로고    scopus 로고
    • DCCT/EDIC Research Group. Effect of glycemic exposure on the risk of microvascular complications in the Diabetes Control and Complications Trial-revisited
    • Lachin JM, Genuth S, Nathan DM, et al. DCCT/EDIC Research Group. Effect of glycemic exposure on the risk of microvascular complications in the Diabetes Control and Complications Trial-revisited. Diabetes. 2008;57:995-1001.
    • (2008) Diabetes , vol.57 , pp. 995-1001
    • Lachin, J.M.1    Genuth, S.2    Nathan, D.M.3
  • 7
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • El-Osta A, Brasacchio D, Yao D, et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med. 2008;205:2409-2417.
    • (2008) J Exp Med , vol.205 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3
  • 8
    • 84960144959 scopus 로고    scopus 로고
    • Carrat´u A, et al. GLP-1 Cleavage product reverses persistent ROS generation after transient hyperglycemia by disrupting an ROS-generating feedback loop
    • Giacco F, Du X, Carrat´u A, et al. GLP-1 Cleavage product reverses persistent ROS generation after transient hyperglycemia by disrupting an ROS-generating feedback loop. Diabetes. 2015;64:3273-3284.
    • (2015) Diabetes , vol.64 , pp. 3273-3284
    • Giacco, F.1    Du, X.2
  • 9
    • 84055204963 scopus 로고    scopus 로고
    • Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid
    • Santos JM, Kowluru RA. Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid. Invest Ophthalmol Vis Sci. 2011;52:8791-8798.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 8791-8798
    • Santos, J.M.1    Kowluru, R.A.2
  • 10
    • 84939260083 scopus 로고    scopus 로고
    • Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy
    • Kowluru RA, Kowluru A, Mishra M, Kumar B. Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res. 2015;48:40-61.
    • (2015) Prog Retin Eye Res , vol.48 , pp. 40-61
    • Kowluru, R.A.1    Kowluru, A.2    Mishra, M.3    Kumar, B.4
  • 13
    • 84905693954 scopus 로고    scopus 로고
    • Micro-RNA-146 inhibits thrombin-induced NF-kappaB activation and subsequent inflammatory responses in human retinal endothelial cells
    • Cowan C, Muraleedharan CK, O’Donnell JJ III, et al. Micro-RNA-146 inhibits thrombin-induced NF-kappaB activation and subsequent inflammatory responses in human retinal endothelial cells. Invest Ophthalmol Vis Sci. 2014;55:4944-4951.
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 4944-4951
    • Cowan, C.1    Muraleedharan, C.K.2    O’Donnell, J.3
  • 14
    • 84907558266 scopus 로고    scopus 로고
    • MiRNA-dependent cross-talk between VEGF and Ang-2 in hypoxia-induced microvascular dysfunction
    • Zhao R, Qian L, Jiang L. miRNA-dependent cross-talk between VEGF and Ang-2 in hypoxia-induced microvascular dysfunction. Biochem Biophys Res Commun. 2014;452:428-435.
    • (2014) Biochem Biophys Res Commun , vol.452 , pp. 428-435
    • Zhao, R.1    Qian, L.2    Jiang, L.3
  • 15
    • 0036517850 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression
    • Joussen AM, Poulaki V, Mitsiades N, et al. Nonsteroidal antiinflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression. FASEB J. 2002;16:438-440.
    • (2002) FASEB J , vol.16 , pp. 438-440
    • Joussen, A.M.1    Poulaki, V.2    Mitsiades, N.3
  • 16
    • 33847048626 scopus 로고    scopus 로고
    • Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia
    • Vincent JA, Mohr S. Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia. Diabetes. 2007;56:224-230.
    • (2007) Diabetes , vol.56 , pp. 224-230
    • Vincent, J.A.1    Mohr, S.2
  • 18
    • 84856404530 scopus 로고    scopus 로고
    • Role of inflammation in the pathogenesis of diabetic retinopathy
    • El-Asrar AM. Role of inflammation in the pathogenesis of diabetic retinopathy. Middle East Afr J Ophthalmol. 2012;19: 70-74.
    • (2012) Middle East Afr J Ophthalmol , vol.19 , pp. 70-74
    • El-Asrar, A.M.1
  • 19
    • 33845546564 scopus 로고    scopus 로고
    • Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy
    • Demircan N, Safran BG, Soylu M, Ozcan AA, Sizmaz S. Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy. Eye. 2006;20:1366-1369.
    • (2006) Eye , vol.20 , pp. 1366-1369
    • Demircan, N.1    Safran, B.G.2    Soylu, M.3    Ozcan, A.A.4    Sizmaz, S.5
  • 20
    • 79960072567 scopus 로고    scopus 로고
    • Expression profiles of cytokines and chemokines in vitreous fluid in diabetic retinopathy and central retinal vein occlusion
    • Suzuki Y, Nakazawa M, Suzuki K, et al. Expression profiles of cytokines and chemokines in vitreous fluid in diabetic retinopathy and central retinal vein occlusion. Jpn J Ophthalmol. 2011;55:256-263.
    • (2011) Jpn J Ophthalmol , vol.55 , pp. 256-263
    • Suzuki, Y.1    Nakazawa, M.2    Suzuki, K.3
  • 21
    • 7044228789 scopus 로고    scopus 로고
    • A central role for inflammation in the pathogenesis of diabetic retinopathy
    • Joussen AM, Poulaki V, Le ML, et al. A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J. 2004;18:1450-1452.
    • (2004) FASEB J , vol.18 , pp. 1450-1452
    • Joussen, A.M.1    Poulaki, V.2    Le, M.L.3
  • 22
    • 33847037432 scopus 로고    scopus 로고
    • Salicylate-based antiinflammatory drugs inhibit the early lesion of diabetic retinopathy
    • Zheng L, Howell SJ, Hatala DA, et al. Salicylate-based antiinflammatory drugs inhibit the early lesion of diabetic retinopathy. Diabetes. 2007;56:337-345.
    • (2007) Diabetes , vol.56 , pp. 337-345
    • Zheng, L.1    Howell, S.J.2    Hatala, D.A.3
  • 23
    • 77954264059 scopus 로고    scopus 로고
    • Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy
    • Schwartzman ML, Iserovich P, Gotlinger K, et al. Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy. Diabetes. 2010;59: 1780-1788.
    • (2010) Diabetes , vol.59 , pp. 1780-1788
    • Schwartzman, M.L.1    Iserovich, P.2    Gotlinger, K.3
  • 24
    • 84962191237 scopus 로고    scopus 로고
    • Intravitreal AAV2.COMPAng1 prevents neurovascular degeneration in a murine model of diabetic retinopathy
    • Cahoon JM, Rai RR, Carroll LS, et al. Intravitreal AAV2.COMPAng1 prevents neurovascular degeneration in a murine model of diabetic retinopathy. Diabetes. 2015;64:4247-4259.
    • (2015) Diabetes , vol.64 , pp. 4247-4259
    • Cahoon, J.M.1    Rai, R.R.2    Carroll, L.S.3
  • 25
    • 84885357617 scopus 로고    scopus 로고
    • Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina
    • Du Y, Veenstra A, Palczewski K, Kern TS. Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina. Proc Natl Acad Sci U S A. 2013;110:16586-16591.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 16586-16591
    • Du, Y.1    Veenstra, A.2    Palczewski, K.3    Kern, T.S.4
  • 26
    • 84885105118 scopus 로고    scopus 로고
    • Neuron-derived semaphorin 3A is an early inducer of vascular permeability in diabetic retinopathy via neuropilin-1
    • Cerani A, Tetreault N, Menard C, et al. Neuron-derived semaphorin 3A is an early inducer of vascular permeability in diabetic retinopathy via neuropilin-1. Cell Metab. 2013;18: 505-518.
    • (2013) Cell Metab , vol.18 , pp. 505-518
    • Cerani, A.1    Tetreault, N.2    Menard, C.3
  • 27
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
    • Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Ann Rev Pharmacol Toxicol. 2007;47:89-116.
    • (2007) Ann Rev Pharmacol Toxicol , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 28
    • 84890982027 scopus 로고    scopus 로고
    • NRF2 plays a protective role in diabetic retinopathy in mice
    • Xu Z, Wei Y, Gong J, et al. NRF2 plays a protective role in diabetic retinopathy in mice. Diabetologia. 2014;57:204-213.
    • (2014) Diabetologia , vol.57 , pp. 204-213
    • Xu, Z.1    Wei, Y.2    Gong, J.3
  • 29
    • 84926675634 scopus 로고    scopus 로고
    • Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion
    • Xu Z, Cho H, Hartsock MJ, et al. Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion. J Neurochem. 2015;133:233-241.
    • (2015) J Neurochem , vol.133 , pp. 233-241
    • Xu, Z.1    Cho, H.2    Hartsock, M.J.3
  • 30
    • 84878804327 scopus 로고    scopus 로고
    • Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy
    • Zhong Q, Mishra M, Kowluru RA. Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2013;54: 3941-3948.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 3941-3948
    • Zhong, Q.1    Mishra, M.2    Kowluru, R.A.3
  • 31
    • 84921889428 scopus 로고    scopus 로고
    • Epigenetic modifications of Keap1 regulate its interaction with the protective factor Nrf2 in the development of diabetic retinopathy
    • Mishra M, Zhong Q, Kowluru RA. Epigenetic modifications of Keap1 regulate its interaction with the protective factor Nrf2 in the development of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2014;55:7256-7265.
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 7256-7265
    • Mishra, M.1    Zhong, Q.2    Kowluru, R.A.3
  • 32
    • 84906331499 scopus 로고    scopus 로고
    • Epigenetic modifications of Nrf2-mediated glutamate-cysteine ligase: Implications for the development of diabetic retinopathy and the metabolic memory phenomenon associated with its continued progression
    • Mishra M, Zhong Q, Kowluru RA. Epigenetic modifications of Nrf2-mediated glutamate-cysteine ligase: implications for the development of diabetic retinopathy and the metabolic memory phenomenon associated with its continued progression. Free Radic Biol Med. 2014;75:129-139.
    • (2014) Free Radic Biol Med , vol.75 , pp. 129-139
    • Mishra, M.1    Zhong, Q.2    Kowluru, R.A.3
  • 33
    • 79956213781 scopus 로고    scopus 로고
    • Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: The joslin 50-year medalist study
    • Sun JK, Keenan HA, Cavallerano JD. Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study. Diabetes Care. 2011;34:968-974.
    • (2011) Diabetes Care , vol.34 , pp. 968-974
    • Sun, J.K.1    Keenan, H.A.2    Cavallerano, J.D.3
  • 34
    • 0025319722 scopus 로고
    • Ultrastructural localization of extracellular matrix components in human retinal vessels and Bruch’s membrane
    • Das A, Frank RN, Zhang NL, Turczyn TJ. Ultrastructural localization of extracellular matrix components in human retinal vessels and Bruch’s membrane. Arch Ophthalmol. 1990;108:421-429.
    • (1990) Arch Ophthalmol , vol.108 , pp. 421-429
    • Das, A.1    Frank, R.N.2    Zhang, N.L.3    Turczyn, T.J.4
  • 35
    • 0001505189 scopus 로고
    • An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes
    • Antonelli-Orlidge A, Saunders KB, Smith SR, D’Amore PA. An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. Proc Natl Acad Sci U S A. 1989;86:4544-4548.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 4544-4548
    • Antonelli-Orlidge, A.1    Saunders, K.B.2    Smith, S.R.3    D’Amore, P.A.4
  • 36
    • 0031737671 scopus 로고    scopus 로고
    • Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: Vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group
    • Antonetti DA, Barber AJ, Khin S, et al. Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group. Diabetes. 1998;47:1953-1959.
    • (1998) Diabetes , vol.47 , pp. 1953-1959
    • Antonetti, D.A.1    Barber, A.J.2    Khin, S.3
  • 37
    • 84907008498 scopus 로고    scopus 로고
    • Canonical WNT signaling components in vascular development and barrier function
    • Zhou Y, Wang Y, Tischfield M, et al. Canonical WNT signaling components in vascular development and barrier function. J Clin Invest. 2014;124:3825-3846.
    • (2014) J Clin Invest , vol.124 , pp. 3825-3846
    • Zhou, Y.1    Wang, Y.2    Tischfield, M.3
  • 38
    • 84919372584 scopus 로고    scopus 로고
    • Retinal microangiopathy in a mouse model of inducible mural cell loss
    • Valdez CN, Arboleda-Velasquez JF, Amarnani DS, et al. Retinal microangiopathy in a mouse model of inducible mural cell loss. Am J Pathol. 2014;184:2618-2626.
    • (2014) Am J Pathol , vol.184 , pp. 2618-2626
    • Valdez, C.N.1    Arboleda-Velasquez, J.F.2    Amarnani, D.S.3
  • 39
    • 79960731769 scopus 로고    scopus 로고
    • High glucoseinduced altered basement membrane composition and structure increases trans-endothelial permeability: Implications for diabetic retinopathy
    • Chronopoulos A, Trudeau K, Roy S, et al. High glucoseinduced altered basement membrane composition and structure increases trans-endothelial permeability: implications for diabetic retinopathy. Curr Eye Res. 2011;36:747-753.
    • (2011) Curr Eye Res , vol.36 , pp. 747-753
    • Chronopoulos, A.1    Trudeau, K.2    Roy, S.3
  • 40
    • 78650073594 scopus 로고    scopus 로고
    • High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: Mechanism for compromised extracellular matrix barrier function
    • Chronopoulos A, Tang A, Beglova E, et al. High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function. Diabetes. 2010;59:3159-3166.
    • (2010) Diabetes , vol.59 , pp. 3159-3166
    • Chronopoulos, A.1    Tang, A.2    Beglova, E.3
  • 41
    • 0035086992 scopus 로고    scopus 로고
    • The absence of diabetic retinopathy in patients with retinitis pigmentosa: Implications for pathophysiology and possible treatment
    • Arden GB. The absence of diabetic retinopathy in patients with retinitis pigmentosa: implications for pathophysiology and possible treatment. Br J Ophthalmol. 2001;85:366-370.
    • (2001) Br J Ophthalmol , vol.85 , pp. 366-370
    • Arden, G.B.1
  • 42
    • 84940479597 scopus 로고    scopus 로고
    • Retinylamine benefits early diabetic retinopathy in mice
    • Liu H, Tang J, Du Y, et al. Retinylamine benefits early diabetic retinopathy in mice. J Biol Chem. 2015;290:21568-21579.
    • (2015) J Biol Chem , vol.290 , pp. 21568-21579
    • Liu, H.1    Tang, J.2    Du, Y.3
  • 43
    • 84976285388 scopus 로고    scopus 로고
    • CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes
    • Beli E, Dominguez JM II, Hu P, et al. CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes. J Mol Med (Berl). 2016;94:1255-1265.
    • (2016) J Mol Med (Berl) , vol.94 , pp. 1255-1265
    • Beli, E.1    Dominguez, J.2    Hu, P.3
  • 44
    • 84867241267 scopus 로고    scopus 로고
    • The use of forward scatter to improve retinal vascular imaging with an adaptive optics scanning laser ophthalmoscope
    • Chui TYP, Vannasdale DA, Burns SA. The use of forward scatter to improve retinal vascular imaging with an adaptive optics scanning laser ophthalmoscope. Biomed Opt Express. 2012;3:2537-2549.
    • (2012) Biomed Opt Express , vol.3 , pp. 2537-2549
    • Chui, T.1    Vannasdale, D.A.2    Burns, S.A.3
  • 45
    • 84895756335 scopus 로고    scopus 로고
    • In vivo adaptive optics microvascular imaging in diabetic patients without clinically severe diabetic retinopathy
    • Burns SA, Elsner AE, Chui TY, et al. In vivo adaptive optics microvascular imaging in diabetic patients without clinically severe diabetic retinopathy. Biomed Opt Express. 2014;5: 961-974.
    • (2014) Biomed Opt Express , vol.5 , pp. 961-974
    • Burns, S.A.1    Elsner, A.E.2    Chui, T.Y.3
  • 46
    • 84917690753 scopus 로고    scopus 로고
    • Assessment of perfused foveal microvascular density and identification of nonperfused capillaries in healthy and vasculopathic eyes
    • Pinhas A, Razeen M, Dubow M, et al. Assessment of perfused foveal microvascular density and identification of nonperfused capillaries in healthy and vasculopathic eyes. Invest Ophthalmol Vis Sci. 2014;55:8056-8066.
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 8056-8066
    • Pinhas, A.1    Razeen, M.2    Dubow, M.3
  • 47
    • 84982085630 scopus 로고    scopus 로고
    • Plasma kallikreinkinin system as a VEGF-independent mediator of diabetic macular edema
    • Kita T, Clermont AC, Murugesan N, et al. Plasma kallikreinkinin system as a VEGF-independent mediator of diabetic macular edema. Diabetes. 2015;64:3588-3599.
    • (2015) Diabetes , vol.64 , pp. 3588-3599
    • Kita, T.1    Clermont, A.C.2    Murugesan, N.3
  • 49
    • 77954654472 scopus 로고    scopus 로고
    • Effects of medical therapies on retinopathy progression in type 2 diabetes
    • The ACCORD Study group, ACCORD Eye Study Group
    • The ACCORD Study group, ACCORD Eye Study Group. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med. 2010;363:233044.
    • (2010) N Engl J Med , vol.363
  • 50
    • 0000559926 scopus 로고
    • A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes
    • University Group Diabetes Program (UGDP)
    • University Group Diabetes Program (UGDP). A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. Diabetes. 1970;19(suppl 2):747-830.
    • (1970) Diabetes , vol.19 , pp. 747-830
  • 51
    • 0003680197 scopus 로고
    • Photocoagulation for diabetic macular edema. ETDRS Report No. 1
    • Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group. Photocoagulation for diabetic macular edema. ETDRS Report No. 1. Arch Ophthalmol. 1985;10:1796-1806.
    • (1985) Arch Ophthalmol , vol.10 , pp. 1796-1806
  • 52
    • 84876248391 scopus 로고    scopus 로고
    • Restoration of retinal structure and function after selective photocoagulation
    • Sher A, Jones BW, Huie P, et al. Restoration of retinal structure and function after selective photocoagulation. J Neurosci. 2013;33:6800-6808.
    • (2013) J Neurosci , vol.33 , pp. 6800-6808
    • Sher, A.1    Jones, B.W.2    Huie, P.3
  • 53
    • 84878460514 scopus 로고    scopus 로고
    • Restoration of retinal morphology and residual scarring after photocoagulation
    • Lavinsky D, Cardillo JA, Mandel Y, et al. Restoration of retinal morphology and residual scarring after photocoagulation. Acta Ophthalmol. 2013;91:e315-e323.
    • (2013) Acta Ophthalmol , vol.91 , pp. e315-e323
    • Lavinsky, D.1    Cardillo, J.A.2    Mandel, Y.3
  • 54
    • 84891886148 scopus 로고    scopus 로고
    • Subvisible retinal laser therapy: Titration algorithm and tissue response
    • Lavinsky D, Sramek C, Wang J, et al. Subvisible retinal laser therapy: titration algorithm and tissue response. Retina. 2014;34:87-97.
    • (2014) Retina , vol.34 , pp. 87-97
    • Lavinsky, D.1    Sramek, C.2    Wang, J.3
  • 55
    • 0023236957 scopus 로고
    • Changing indications and techniques for vitrectomy in management of complications of diabetic retinopathy
    • Aaberg TM, Abrams GW. Changing indications and techniques for vitrectomy in management of complications of diabetic retinopathy. Ophthalmology. 1987;94:775-779.
    • (1987) Ophthalmology , vol.94 , pp. 775-779
    • Aaberg, T.M.1    Abrams, G.W.2
  • 56
    • 84921555945 scopus 로고    scopus 로고
    • Diabetic Retinopathy Clinical Research Network. Intravitreal ranibizumab for diabetic macular edema with prompt versus deferred laser treatment: 5-year randomized trial results
    • Elman MJ, Ayala A, Bressler NM, et al. Diabetic Retinopathy Clinical Research Network. Intravitreal ranibizumab for diabetic macular edema with prompt versus deferred laser treatment: 5-year randomized trial results. Ophthalmology. 2015;122:375-381.
    • (2015) Ophthalmology , vol.122 , pp. 375-381
    • Elman, M.J.1    Ayala, A.2    Bressler, N.M.3
  • 57
    • 84975698767 scopus 로고    scopus 로고
    • Diabetic Retinopathy Clinical Research Network. Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema
    • Wells JA, Glassman AR, Ayala AR, et al.; Diabetic Retinopathy Clinical Research Network. Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. Ophthalmology. 2016;123:1351-1359.
    • (2016) Ophthalmology , vol.123 , pp. 1351-1359
    • Wells, J.A.1    Glassman, A.R.2    Ayala, A.R.3
  • 58
    • 84937739093 scopus 로고    scopus 로고
    • Diabetic macular edema: Pathophysiology and novel therapeutic targets
    • Das A, McGuire PG, Rangasamy S. Diabetic macular edema: pathophysiology and novel therapeutic targets. Ophthalmology. 2015;122:1375-1394.
    • (2015) Ophthalmology , vol.122 , pp. 1375-1394
    • Das, A.1    McGuire, P.G.2    Rangasamy, S.3
  • 59
    • 79955953053 scopus 로고    scopus 로고
    • A potential role of angiopoietin-2 in the regulation of the blood-retinal barrier in diabetic retinopathy
    • Rangasamy S, Srinivasan R, Maestas J, et al. A potential role of angiopoietin-2 in the regulation of the blood-retinal barrier in diabetic retinopathy. Invest Ophthalmol Vis Sci. 2011;52: 3784-3791.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 3784-3791
    • Rangasamy, S.1    Srinivasan, R.2    Maestas, J.3
  • 60
    • 84908200342 scopus 로고    scopus 로고
    • Chemokine mediated monocyte trafficking into the retina: Role of inflammation in alteration of the blood-retinal barrier in diabetic retinopathy
    • Rangasamy S, McGuire PG, Franco Nitta C, et al. Chemokine mediated monocyte trafficking into the retina: role of inflammation in alteration of the blood-retinal barrier in diabetic retinopathy. PLoS One. 2014;9:e108508.
    • (2014) Plos One , vol.9
    • Rangasamy, S.1    McGuire, P.G.2    Franco Nitta, C.3
  • 61
    • 84907494958 scopus 로고    scopus 로고
    • Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature
    • Shen J, Frye M, Lee BL, et al. Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature. J Clin Invest. 2014;124: 4564-4576.
    • (2014) J Clin Invest , vol.124 , pp. 4564-4576
    • Shen, J.1    Frye, M.2    Lee, B.L.3
  • 62
    • 84924082631 scopus 로고    scopus 로고
    • Treatment of diabetic macular edema with an inhibitor of vascular endothelial-protein tyrosine phosphatase that activates Tie2
    • Campochiaro PA, Sophie R, Tolentino M, et al. Treatment of diabetic macular edema with an inhibitor of vascular endothelial-protein tyrosine phosphatase that activates Tie2. Ophthalmology. 2015;122:545-554.
    • (2015) Ophthalmology , vol.122 , pp. 545-554
    • Campochiaro, P.A.1    Sophie, R.2    Tolentino, M.3
  • 63
    • 84892377740 scopus 로고    scopus 로고
    • Potential efficiency benefits of nonmydriatic ultrawide field retinal imaging in an ocular telehealth diabetic retinopathy program
    • Silva PS, Cavallerano JD, Tolls D, et al. Potential efficiency benefits of nonmydriatic ultrawide field retinal imaging in an ocular telehealth diabetic retinopathy program. Diabetes Care. 2014;37:50-55.
    • (2014) Diabetes Care , vol.37 , pp. 50-55
    • Silva, P.S.1    Cavallerano, J.D.2    Tolls, D.3
  • 64
    • 75749107533 scopus 로고    scopus 로고
    • Oscillation of angiogenesis with vascular dropout in diabetic retinopathy by VESsel GENeration analysis (VESGEN)
    • Parsons-Wingerter P, Radhakrishnan K, Vickerman MB, Kaiser PK. Oscillation of angiogenesis with vascular dropout in diabetic retinopathy by VESsel GENeration analysis (VESGEN). Invest Ophthalmol Vis Sci. 2010;51:498-507.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 498-507
    • Parsons-Wingerter, P.1    Radhakrishnan, K.2    Vickerman, M.B.3    Kaiser, P.K.4
  • 65
    • 33847348148 scopus 로고    scopus 로고
    • Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/ progenitor cell principals
    • Yoder MC, Mead LE, Prater D, et al. Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/ progenitor cell principals. Blood. 2007;109:1801-1809.
    • (2007) Blood , vol.109 , pp. 1801-1809
    • Yoder, M.C.1    Mead, L.E.2    Prater, D.3
  • 66
    • 33748969496 scopus 로고    scopus 로고
    • Effects of treatment for diabetes mellitus on circulating vascular progenitor cells
    • Kusuyama T, Omura T, Nishiya D, et al. Effects of treatment for diabetes mellitus on circulating vascular progenitor cells. J Pharmacol Sci. 2006;102:96-102.
    • (2006) J Pharmacol Sci , vol.102 , pp. 96-102
    • Kusuyama, T.1    Omura, T.2    Nishiya, D.3
  • 67
    • 44749087657 scopus 로고    scopus 로고
    • Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes
    • Dotta F, Sorrentino V. Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes. Diabetologia. 2008;51:1296-1305.
    • (2008) Diabetologia , vol.51 , pp. 1296-1305
    • Dotta, F.1    Sorrentino, V.2
  • 68
    • 16444377000 scopus 로고    scopus 로고
    • Obese diabetic mouse environment differentially affects primitive and monocytic endothelial cell progenitors
    • Awad O, Jiao C, Ma N, Dunnwald M, Schatteman GC. Obese diabetic mouse environment differentially affects primitive and monocytic endothelial cell progenitors. Stem Cells. 2005; 23:575-583.
    • (2005) Stem Cells , vol.23 , pp. 575-583
    • Awad, O.1    Jiao, C.2    Ma, N.3    Dunnwald, M.4    Schatteman, G.C.5
  • 69
    • 77950883548 scopus 로고    scopus 로고
    • The promise of cell-based therapies for diabetic complications: Challenges and solutions
    • Jarajapu YP, Grant MB. The promise of cell-based therapies for diabetic complications: challenges and solutions. Circ Res. 2010;106:854-869.
    • (2010) Circ Res , vol.106 , pp. 854-869
    • Jarajapu, Y.P.1    Grant, M.B.2
  • 70
    • 9144271032 scopus 로고    scopus 로고
    • Endothelial progenitor cell dysfunction: A novel concept in the pathogenesis of vascular complications of type 1 diabetes
    • Loomans CJ, de Koning EJ, Staal FJ, et al. Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes. 2004;53:195-199.
    • (2004) Diabetes , vol.53 , pp. 195-199
    • Loomans, C.J.1    De Koning, E.J.2    Staal, F.J.3
  • 71
    • 73949157202 scopus 로고    scopus 로고
    • Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock
    • Busik JV, Tikhonenko M, Bhatwadekar A, et al. Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock. J ExpMed. 2009;206:2897-2906.
    • (2009) J Expmed , vol.206 , pp. 2897-2906
    • Busik, J.V.1    Tikhonenko, M.2    Bhatwadekar, A.3
  • 72
    • 84886684378 scopus 로고    scopus 로고
    • CNS inflammation and bone marrow neuropathy in type 1 diabetes
    • Hu P, Thinschmidt JS, Yan Y, et al. CNS inflammation and bone marrow neuropathy in type 1 diabetes. Am J Pathol. 2013; 183:1608-1620.
    • (2013) Am J Pathol , vol.183 , pp. 1608-1620
    • Hu, P.1    Thinschmidt, J.S.2    Yan, Y.3
  • 73
    • 84929625899 scopus 로고    scopus 로고
    • Loss of survival factors and activation of inflammatory cascades in brain sympathetic centers in type 1 diabetic mice
    • Hu P, Thinschmidt JS, Caballero S, et al. Loss of survival factors and activation of inflammatory cascades in brain sympathetic centers in type 1 diabetic mice. Am J Physiol Endocrinol Metab. 2015;308:E688-E698.
    • (2015) Am J Physiol Endocrinol Metab , vol.308 , pp. E688-E698
    • Hu, P.1    Thinschmidt, J.S.2    Caballero, S.3
  • 74
    • 84863832833 scopus 로고    scopus 로고
    • Bone marrow-CNS connections: Implications in the pathogenesis of diabetic retinopathy
    • Yellowlees DJ, Bhatwadekar AD, Li Calzi S, et al. Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res. 2012;31:481-494.
    • (2012) Prog Retin Eye Res , vol.31 , pp. 481-494
    • Yellowlees, D.J.1    Bhatwadekar, A.D.2    Li Calzi, S.3
  • 75
    • 84928050463 scopus 로고    scopus 로고
    • Vision from next generation sequencing: Multi-dimensional genomewide analysis for producing gene regulatory networks underlying retinal development, aging and disease
    • Yang HJ, Ratnapriya R, Cogliati T, Kim JW, Swaroop A. Vision from next generation sequencing: multi-dimensional genomewide analysis for producing gene regulatory networks underlying retinal development, aging and disease. Prog Retin Eye Res. 2015;46:1-30.
    • (2015) Prog Retin Eye Res , vol.46 , pp. 1-30
    • Yang, H.J.1    Ratnapriya, R.2    Cogliati, T.3    Kim, J.W.4    Swaroop, A.5
  • 76
    • 84889255994 scopus 로고    scopus 로고
    • Nanoparticles in porous microparticles prepared by supercritical infusion and pressure quench technology for sustained delivery of bevacizumab
    • Yandrapu SK, Upadhyay AK, Petrash JM, Kompella UB. Nanoparticles in porous microparticles prepared by supercritical infusion and pressure quench technology for sustained delivery of bevacizumab. Mol Pharmaceutics. 2013; 10:4676-4686.
    • (2013) Mol Pharmaceutics , vol.10 , pp. 4676-4686
    • Yandrapu, S.K.1    Upadhyay, A.K.2    Petrash, J.M.3    Kompella, U.B.4
  • 77
    • 84939493345 scopus 로고    scopus 로고
    • Injectable chemically crosslinked hydrogel for the controlled release of bevacizumab in vitreous: A 6-month in vivo study
    • Yu Y, Lau LC, Lo AC, Chau Y. Injectable chemically crosslinked hydrogel for the controlled release of bevacizumab in vitreous: a 6-month in vivo study. Trans Vis Sci Tech. 2015; 4(2):5.
    • (2015) Trans Vis Sci Tech , vol.4 , Issue.2 , pp. 5
    • Yu, Y.1    Lau, L.C.2    Lo, A.C.3    Chau, Y.4
  • 78
    • 68049142424 scopus 로고    scopus 로고
    • Nanoparticle-mediated expression of an angiogenic inhibitor ameliorates ischemia-induced retinal neovascularization and diabetes-induced retinal vascular leakage
    • Park K, Chen Y, Hu Y, et al. Nanoparticle-mediated expression of an angiogenic inhibitor ameliorates ischemia-induced retinal neovascularization and diabetes-induced retinal vascular leakage. Diabetes. 2009;58:1902-1913.
    • (2009) Diabetes , vol.58 , pp. 1902-1913
    • Park, K.1    Chen, Y.2    Hu, Y.3
  • 79
    • 80051513044 scopus 로고    scopus 로고
    • Anti-inflammatory and antiangiogenic effects of nanoparticle-mediated delivery of a natural angiogenic inhibitor
    • Jin J, Zhou KK, Park K, et al. Anti-inflammatory and antiangiogenic effects of nanoparticle-mediated delivery of a natural angiogenic inhibitor. Invest Ophthalmol Vis Sci. 2011; 52:6230-6237.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 6230-6237
    • Jin, J.1    Zhou, K.K.2    Park, K.3
  • 80
    • 84860129964 scopus 로고    scopus 로고
    • Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model
    • Kannan S, Dai H, Navath RS, et al. Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model. Sci Transl Med. 2012;4:130.
    • (2012) Sci Transl Med , vol.4 , pp. 130
    • Kannan, S.1    Dai, H.2    Navath, R.S.3
  • 81
    • 84913542999 scopus 로고    scopus 로고
    • Molecular probes for imaging of hypoxia in the retina
    • Evans SM, Kim K, Moore CE, et al. Molecular probes for imaging of hypoxia in the retina. Bioconjug Chem. 2014;25: 2030-2037.
    • (2014) Bioconjug Chem , vol.25 , pp. 2030-2037
    • Evans, S.M.1    Kim, K.2    Moore, C.E.3
  • 83
    • 84916898421 scopus 로고    scopus 로고
    • ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease
    • Poole KM, Nelson CE, Joshi RV, et al. ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease. Biomaterials. 2015;41: 166-175.
    • (2015) Biomaterials , vol.41 , pp. 166-175
    • Poole, K.M.1    Nelson, C.E.2    Joshi, R.V.3
  • 85
    • 84879233407 scopus 로고    scopus 로고
    • Matrix metalloproteinase responsive, proximity-activated polymeric nanoparticles for siRNA delivery
    • Li H, Yu SS, Miteva M, et al. Matrix metalloproteinase responsive, proximity-activated polymeric nanoparticles for siRNA delivery. Adv Funct Mater. 2013;23:3040-3052.
    • (2013) Adv Funct Mater , vol.23 , pp. 3040-3052
    • Li, H.1    Yu, S.S.2    Miteva, M.3
  • 86
    • 84884685295 scopus 로고    scopus 로고
    • Inhibition of GluN2A-containing Nmethyl-D-aspartate receptors by 2-naphthoic acid
    • Yu H, Popescu GK. Inhibition of GluN2A-containing Nmethyl-D-aspartate receptors by 2-naphthoic acid. Mol Pharmacol. 2013;84:541-550.
    • (2013) Mol Pharmacol , vol.84 , pp. 541-550
    • Yu, H.1    Popescu, G.K.2


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