-
2
-
-
77952779304
-
Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
-
e1035
-
Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, et al. (2010) Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 117: 1064-1077.e1035.
-
(2010)
Ophthalmology
, vol.117
, pp. 1064-1077
-
-
Elman, M.J.1
Aiello, L.P.2
Beck, R.W.3
Bressler, N.M.4
Bressler, S.B.5
-
3
-
-
0036216417
-
Is diabetic retinopathy an inflammatory disease?
-
Adamis AP (2002) Is diabetic retinopathy an inflammatory disease? Br J Ophthalmol 86: 363-365.
-
(2002)
Br J Ophthalmol
, vol.86
, pp. 363-365
-
-
Adamis, A.P.1
-
4
-
-
42449135678
-
Immunological mechanisms in the pathogenesis of diabetic retinopathy
-
Adamis AP, Berman AJ (2008) Immunological mechanisms in the pathogenesis of diabetic retinopathy. Semin Immunopathol 30: 65-84.
-
(2008)
Semin Immunopathol
, vol.30
, pp. 65-84
-
-
Adamis, A.P.1
Berman, A.J.2
-
5
-
-
41149099068
-
Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy
-
Kern TS (2007) Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Exp Diabetes Res 2007: 95103.
-
(2007)
Exp Diabetes Res
, vol.2007
-
-
Kern, T.S.1
-
6
-
-
0030923371
-
Relationship of polymorphonuclear leukocytes to capillary dropout in the human diabetic choroid
-
Lutty GA, Cao J, McLeod DS (1997) Relationship of polymorphonuclear leukocytes to capillary dropout in the human diabetic choroid. Am J Pathol 151: 707-714.
-
(1997)
Am J Pathol
, vol.151
, pp. 707-714
-
-
Lutty, G.A.1
Cao, J.2
McLeod, D.S.3
-
7
-
-
0035139461
-
Leukocyte-mediated endothelial cell injury and death in the diabetic retina
-
Joussen AM, Murata T, Tsujikawa A, Kirchhof B, Bursell SE, et al. (2001) Leukocyte-mediated endothelial cell injury and death in the diabetic retina. Am J Pathol 158: 147-152.
-
(2001)
Am J Pathol
, vol.158
, pp. 147-152
-
-
Joussen, A.M.1
Murata, T.2
Tsujikawa, A.3
Kirchhof, B.4
Bursell, S.E.5
-
8
-
-
0025769620
-
Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy
-
Schröder S, Palinski W, Schmid-Schönbein GW (1991) Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy. Am J Pathol 139: 81-100.
-
(1991)
Am J Pathol
, vol.139
, pp. 81-100
-
-
Schröder, S.1
Palinski, W.2
Schmid-Schönbein, G.W.3
-
9
-
-
0029162588
-
Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid
-
McLeod DS, Lefer DJ, Merges C, Lutty GA (1995) Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid. Am J Pathol 147: 642-653.
-
(1995)
Am J Pathol
, vol.147
, pp. 642-653
-
-
McLeod, D.S.1
Lefer, D.J.2
Merges, C.3
Lutty, G.A.4
-
10
-
-
17844381920
-
Neutrophils are associated with capillary closure in spontaneously diabetic monkey retinas
-
Kim SY, Johnson MA, McLeod DS, Alexander T, Hansen BC, et al. (2005) Neutrophils are associated with capillary closure in spontaneously diabetic monkey retinas. Diabetes 54: 1534-1542.
-
(2005)
Diabetes
, vol.54
, pp. 1534-1542
-
-
Kim, S.Y.1
Johnson, M.A.2
McLeod, D.S.3
Alexander, T.4
Hansen, B.C.5
-
11
-
-
0031897387
-
Hyperglycemia-induced circulating ICAM-1 increase in diabetes mellitus: The possible role of oxidative stress
-
Ceriello A, Falleti E, Motz E, Taboga C, Tonutti L, et al. (1998) Hyperglycemia-induced circulating ICAM-1 increase in diabetes mellitus: the possible role of oxidative stress. Horm Metab Res 30: 146-149.
-
(1998)
Horm Metab Res
, vol.30
, pp. 146-149
-
-
Ceriello, A.1
Falleti, E.2
Motz, E.3
Taboga, C.4
Tonutti, L.5
-
12
-
-
7044228789
-
A Central role for inflammation in the pathogenesis of diabetic retinopathy
-
Joussen AM, Poulaki V, Le ML, Koizumi K, Esser C, et al. (2004) A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J 18: 1450-1452.
-
(2004)
FASEB J
, vol.18
, pp. 1450-1452
-
-
Joussen, A.M.1
Poulaki, V.2
Le, M.L.3
Koizumi, K.4
Esser, C.5
-
13
-
-
0025141464
-
Human monocyte chemoattractant protein-1 (MCP-1)
-
Leonard EJ, Yoshimura T (1990) Human monocyte chemoattractant protein-1 (MCP-1). Immunol Today 11: 97-101.
-
(1990)
Immunol Today
, vol.11
, pp. 97-101
-
-
Leonard, E.J.1
Yoshimura, T.2
-
14
-
-
0032472005
-
C-C chemokines in the vitreous of patients with proliferative vitreoretinopathy and proliferative diabetic retinopathy
-
Capeans C, De Rojas MV, Lojo S, Salorio MS (1998) C-C chemokines in the vitreous of patients with proliferative vitreoretinopathy and proliferative diabetic retinopathy. Retina 18: 546-550.
-
(1998)
Retina
, vol.18
, pp. 546-550
-
-
Capeans, C.1
De Rojas, M.V.2
Lojo, S.3
Salorio, M.S.4
-
15
-
-
10244241784
-
Aqueous levels of macrophage migration inhibitory factor and monocyte chemotactic protein-1 in patients with diabetic retinopathy
-
Tashimo A, Mitamura Y, Nagai S, Nakamura Y, Ohtsuka K, et al. (2004) Aqueous levels of macrophage migration inhibitory factor and monocyte chemotactic protein-1 in patients with diabetic retinopathy. Diabet Med 21: 1292-1297.
-
(2004)
Diabet Med
, vol.21
, pp. 1292-1297
-
-
Tashimo, A.1
Mitamura, Y.2
Nagai, S.3
Nakamura, Y.4
Ohtsuka, K.5
-
16
-
-
78049283701
-
Angiogenic and inflammatory markers in the intraocular fluid of eyes with diabetic macular edema and influence of therapy with bevacizumab
-
Funk M, Schmidinger G, Maar N, Bolz M, Benesch T, et al. (2010) Angiogenic and inflammatory markers in the intraocular fluid of eyes with diabetic macular edema and influence of therapy with bevacizumab. Retina 30: 1412-1419.
-
(2010)
Retina
, vol.30
, pp. 1412-1419
-
-
Funk, M.1
Schmidinger, G.2
Maar, N.3
Bolz, M.4
Benesch, T.5
-
17
-
-
34250160902
-
Multiplex bead analysis of vitreous humor of patients with vitreoretinal disorders
-
Banerjee S, Savant V, Scott RA, Curnow SJ, Wallace GR, et al. (2007) Multiplex bead analysis of vitreous humor of patients with vitreoretinal disorders. Invest Ophthalmol Vis Sci 48: 2203-2207.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 2203-2207
-
-
Banerjee, S.1
Savant, V.2
Scott, R.A.3
Curnow, S.J.4
Wallace, G.R.5
-
18
-
-
77953811798
-
Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism as a potential risk factor for diabetic retinopathy in Japanese patients with type 2 diabetes
-
Katakami N, Matsuhisa M, Kaneto H, Matsuoka TA, Imamura K, et al. (2010) Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism as a potential risk factor for diabetic retinopathy in Japanese patients with type 2 diabetes. Diabetes Res Clin Pract 89: e9-12.
-
(2010)
Diabetes Res Clin Pract
, vol.89
, pp. e9-12
-
-
Katakami, N.1
Matsuhisa, M.2
Kaneto, H.3
Matsuoka, T.A.4
Imamura, K.5
-
19
-
-
79955953053
-
A potential role for angiopoietin 2 in the regulation of the blood-retinal barrier in diabetic retinopathy
-
Rangasamy S, Srinivasan R, Maestas J, McGuire PG, Das A (2011) A potential role for angiopoietin 2 in the regulation of the blood-retinal barrier in diabetic retinopathy. Invest Ophthalmol Vis Sci 52: 3784-3791.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 3784-3791
-
-
Rangasamy, S.1
Srinivasan, R.2
Maestas, J.3
McGuire, P.G.4
Das, A.5
-
20
-
-
0031660311
-
In vivo demonstration of increased leukocyte entrapment in retinal microcirculation of diabetic rats
-
Miyamoto K, Hiroshiba N, Tsujikawa A, Ogura Y (1998) In vivo demonstration of increased leukocyte entrapment in retinal microcirculation of diabetic rats. Invest Ophthalmol Vis Sci 39: 2190-2194.
-
(1998)
Invest Ophthalmol Vis Sci
, vol.39
, pp. 2190-2194
-
-
Miyamoto, K.1
Hiroshiba, N.2
Tsujikawa, A.3
Ogura, Y.4
-
21
-
-
0032863021
-
Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition
-
Miyamoto K, Khosrof S, Bursell SE, Rohan R, Murata T, et al. (1999) Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition. Proc Natl Acad Sci U S A 96: 10836-10841.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10836-10841
-
-
Miyamoto, K.1
Khosrof, S.2
Bursell, S.E.3
Rohan, R.4
Murata, T.5
-
22
-
-
0034028817
-
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
-
Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, et al. (2000) Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 20: 4106-4114.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4106-4114
-
-
Jung, S.1
Aliberti, J.2
Graemmel, P.3
Sunshine, M.J.4
Kreutzberg, G.W.5
-
23
-
-
0025786684
-
Glial changes following an excitotoxic lesion in the CNS-I. Microglia/macrophages
-
Marty S, Dusart I, Peschanski M (1991) Glial changes following an excitotoxic lesion in the CNS-I. Microglia/macrophages. Neuroscience 45: 529-539.
-
(1991)
Neuroscience
, vol.45
, pp. 529-539
-
-
Marty, S.1
Dusart, I.2
Peschanski, M.3
-
24
-
-
0042320662
-
Increased morphological diversity of microglia in the activated hypothalamic supraoptic nucleus
-
Ayoub AE, Salm AK (2003) Increased morphological diversity of microglia in the activated hypothalamic supraoptic nucleus. J Neurosci 23: 7759-7766.
-
(2003)
J Neurosci
, vol.23
, pp. 7759-7766
-
-
Ayoub, A.E.1
Salm, A.K.2
-
25
-
-
0035101188
-
Dynamics of microglial activation: A confocal time-lapse analysis in hippocampal slices
-
Stence N, Waite M, Dailey ME (2001) Dynamics of microglial activation: a confocal time-lapse analysis in hippocampal slices. Glia 33: 256-266.
-
(2001)
Glia
, vol.33
, pp. 256-266
-
-
Stence, N.1
Waite, M.2
Dailey, M.E.3
-
27
-
-
33646823302
-
Protein kinase calpha-rhoa cross-talk in CCL2-induced alterations in brain endothelial permeability
-
Stamatovic SM, Dimitrijevic OB, Keep RF, Andjelkovic AV (2006) Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. J Biol Chem 281: 8379-8388.
-
(2006)
J Biol Chem
, vol.281
, pp. 8379-8388
-
-
Stamatovic, S.M.1
Dimitrijevic, O.B.2
Keep, R.F.3
Andjelkovic, A.V.4
-
28
-
-
58149178530
-
Chemokine receptor antagonists: Overcoming developmental hurdles
-
Horuk R (2009) Chemokine receptor antagonists: overcoming developmental hurdles. Nat Rev Drug Discov 8: 23-33.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 23-33
-
-
Horuk, R.1
-
29
-
-
75949126309
-
Therapeutic targeting of chemokine interactions in atherosclerosis
-
Koenen RR, Weber C (2010) Therapeutic targeting of chemokine interactions in atherosclerosis. Nat Rev Drug Discov 9: 141-153.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 141-153
-
-
Koenen, R.R.1
Weber, C.2
-
30
-
-
67650457597
-
CCR3 is a target for age-related macular degeneration diagnosis and therapy
-
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, et al. (2009) CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature 460: 225-230.
-
(2009)
Nature
, vol.460
, pp. 225-230
-
-
Takeda, A.1
Baffi, J.Z.2
Kleinman, M.E.3
Cho, W.G.4
Nozaki, M.5
-
31
-
-
53149121027
-
MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy
-
Davies MH, Stempel AJ, Powers MR (2008) MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy. Invest Ophthalmol Vis Sci 49: 4195-4202.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 4195-4202
-
-
Davies, M.H.1
Stempel, A.J.2
Powers, M.R.3
-
32
-
-
33847386310
-
Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis
-
Nakazawa T, Hisatomi T, Nakazawa C, Noda K, Maruyama K, et al. (2007) Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis. Proc Natl Acad Sci U S A 104: 2425-2430.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2425-2430
-
-
Nakazawa, T.1
Hisatomi, T.2
Nakazawa, C.3
Noda, K.4
Maruyama, K.5
-
33
-
-
33644693852
-
Serum inflammatory markers in diabetic retinopathy
-
Meleth AD, Agrón E, Chan CC, Reed GF, Arora K, et al. (2005) Serum inflammatory markers in diabetic retinopathy. Invest Ophthalmol Vis Sci 46: 4295-4301.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 4295-4301
-
-
Meleth, A.D.1
Agrón, E.2
Chan, C.C.3
Reed, G.F.4
Arora, K.5
-
34
-
-
84870383668
-
Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice
-
Li G, Veenstra AA, Talahalli RR, Wang X, Gubitosi-Klug RA, et al. (2012) Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice. Diabetes 61: 3294-3303.
-
(2012)
Diabetes
, vol.61
, pp. 3294-3303
-
-
Li, G.1
Veenstra, A.A.2
Talahalli, R.R.3
Wang, X.4
Gubitosi-Klug, R.A.5
-
35
-
-
84864124140
-
CD11b+ bone marrow-derived monocytes are the major leukocyte subset responsible for retinal capillary leukostasis in experimental diabetes in mouse and express high levels of CCR5 in the circulation
-
Serra AM, Waddell J, Manivannan A, Xu H, Cotter M, et al. (2012) CD11b+ bone marrow-derived monocytes are the major leukocyte subset responsible for retinal capillary leukostasis in experimental diabetes in mouse and express high levels of CCR5 in the circulation. Am J Pathol 181: 719-727.
-
(2012)
Am J Pathol
, vol.181
, pp. 719-727
-
-
Serra, A.M.1
Waddell, J.2
Manivannan, A.3
Xu, H.4
Cotter, M.5
-
36
-
-
0031737671
-
Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: Vascular endothelial growth factor decreases occludin in retinal endothelial cells
-
Penn State Retina Research Group
-
Antonetti DA, Barber AJ, Khin S, Lieth E, Tarbell JM, et al. (1998) Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group. Diabetes 47: 1953-1959.
-
(1998)
Diabetes
, vol.47
, pp. 1953-1959
-
-
Antonetti, D.A.1
Barber, A.J.2
Khin, S.3
Lieth, E.4
Tarbell, J.M.5
-
37
-
-
33947313405
-
VEGF activation of protein kinase C stimulates occludin phosphorylation and contributes to endothelial permeability
-
Harhaj NS, Felinski EA, Wolpert EB, Sundstrom JM, Gardner TW, et al. (2006) VEGF activation of protein kinase C stimulates occludin phosphorylation and contributes to endothelial permeability. Invest Ophthalmol Vis Sci 47: 5106-5115.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 5106-5115
-
-
Harhaj, N.S.1
Felinski, E.A.2
Wolpert, E.B.3
Sundstrom, J.M.4
Gardner, T.W.5
-
38
-
-
84877347685
-
Monocytes conditioned media stimulate fibronectin expression and spreading of inflammatory breast cancer cells in three-dimensional culture: A mechanism mediated by IL-8 signaling pathway
-
Mohamed MM (2012) Monocytes conditioned media stimulate fibronectin expression and spreading of inflammatory breast cancer cells in three-dimensional culture: A mechanism mediated by IL-8 signaling pathway. Cell Commun Signal 10: 3.
-
(2012)
Cell Commun Signal
, vol.10
, pp. 3
-
-
Mohamed, M.M.1
-
39
-
-
34548397756
-
Proteolytic degradation of VE-cadherin alters the blood-retinal barrier in diabetes
-
Navaratna D, McGuire PG, Menicucci G, Das A (2007) Proteolytic degradation of VE-cadherin alters the blood-retinal barrier in diabetes. Diabetes 56: 2380-2387.
-
(2007)
Diabetes
, vol.56
, pp. 2380-2387
-
-
Navaratna, D.1
McGuire, P.G.2
Menicucci, G.3
Das, A.4
-
40
-
-
53149116704
-
Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy
-
Lee JE, Liang KJ, Fariss RN, Wong WT (2008) Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy. Invest Ophthalmol Vis Sci 49: 4169-4176.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 4169-4176
-
-
Lee, J.E.1
Liang, K.J.2
Fariss, R.N.3
Wong, W.T.4
-
41
-
-
79956028114
-
Early focal expression of the chemokine ccl2 by müller cells during exposure to damage-inducing bright continuous light
-
Rutar M, Natoli R, Valter K, Provis JM (2011) Early focal expression of the chemokine Ccl2 by Müller cells during exposure to damage-inducing bright continuous light. Invest Ophthalmol Vis Sci 52: 2379-2388.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 2379-2388
-
-
Rutar, M.1
Natoli, R.2
Valter, K.3
Provis, J.M.4
-
42
-
-
66849118559
-
NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation
-
Zhang W, Rojas M, Lilly B, Tsai NT, Lemtalsi T, et al. (2009) NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation. Invest Ophthalmol Vis Sci 50: 3033-3040.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 3033-3040
-
-
Zhang, W.1
Rojas, M.2
Lilly, B.3
Tsai, N.T.4
Lemtalsi, T.5
-
43
-
-
84885031592
-
Effects of high glucose-induced cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells
-
Tien T, Barrette KF, Chronopoulos A, Roy S (2013) Effects of high glucose-induced Cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells. Invest Ophthalmol Vis Sci 54: 6518-6525.
-
(2013)
Invest Ophthalmol Vis Sci
, vol.54
, pp. 6518-6525
-
-
Tien, T.1
Barrette, K.F.2
Chronopoulos, A.3
Roy, S.4
-
44
-
-
44949130856
-
MCP-1/CCL2: A new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy
-
Tesch GH (2008) MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy. Am J Physiol Renal Physiol 294: F697-701.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F697-701
-
-
Tesch, G.H.1
|