NRF2 plays a protective role in diabetic retinopathy in mice

Diabetologia

Volumn 57, Issue 1, 2014, Pages 204-213

  Xu, Zhenhua ^a   Wei, Yanhong ^a   Gong, Junsong ^a   Cho, Hongkwan ^a   Park, James K ^a   Sung, Ee Rah ^b   Huang, Hu ^a   Wu, Lijuan ^a   Eberhart, Charles ^a   Handa, James T ^a   Du, Yunpeng ^c   Kern, Timothy S ^c,d   Thimmulappa, Rajesh ^e   Barber, Alistair J ^b   Biswal, Shyam ^e   Duh, Elia J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^e JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Diabetic retinopathy; Inflammation; M ller glial cells; Neuronal dysfunction; NF E2 related factor 2; Reactive oxygen species; Transcription factor; Vascular permeability

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; GLUTATHIONE; HYDROGEN PEROXIDE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STREPTOZOCIN; SUPEROXIDE; TERT BUTYL HYDROPEROXIDE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD RETINA BARRIER; BLOOD VESSEL PERMEABILITY; BODY WEIGHT; CELL LINE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DISEASE EXACERBATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLIA CELL; GLIAL CELL CULTURE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KNOCKOUT MOUSE; MICROGLIA; MOUSE; NERVE FIBER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RETINA; STREPTOZOTOCIN-INDUCED DIABETIC NEUROPATHY; UBIQUITINATION; VISION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; CELL LINE; DIABETIC RETINOPATHY; HUMANS; MALE; MICE; MICE, MUTANT STRAINS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RETINA;

EID: 84890982027     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3093-8     Document Type: Article

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