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Volumn 55, Issue 8, 2014, Pages 4944-4951

MicroRNA-146 inhibits thrombin-induced NF-κB activation and subsequent inflammatory responses in human retinal endothelial cells

Author keywords

Diabetic retinopathy; MicroRNA; NF b activation; Retinal endothelial cells; Thrombin

Indexed keywords

DIABETIC RETINOPATHY; MICRORNA; NF-KB ACTIVATION; RETINAL ENDOTHELIAL CELLS; THROMBIN;

EID: 84905693954     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-13631     Document Type: Article
Times cited : (82)

References (51)
  • 1
    • 1842530296 scopus 로고    scopus 로고
    • Causes and prevalence of visual impairment among adults in the United States
    • Congdon N, O'Colmain B, Klaver CC, et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol. 2004;122:477-485.
    • (2004) Arch Ophthalmol , vol.122 , pp. 477-485
    • Congdon, N.1    O'Colmain, B.2    Klaver, C.C.3
  • 2
    • 0021136256 scopus 로고
    • The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years
    • Klein R, Klein BE, Moss SE, Davis MD, DeMets DL. The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol. 1984;102: 520-526.
    • (1984) Arch Ophthalmol , vol.102 , pp. 520-526
    • Klein, R.1    Klein, B.E.2    Moss, S.E.3    Davis, M.D.4    Demets, D.L.5
  • 3
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 4
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature. 2004; 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 5
    • 80052333875 scopus 로고    scopus 로고
    • MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats
    • Kovacs B, Lumayag S, Cowan C, Xu S. MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats. Invest Ophthalmol Vis Sci. 2011;52:4402-4409.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 4402-4409
    • Kovacs, B.1    Lumayag, S.2    Cowan, C.3    Xu, S.4
  • 6
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A. 2006;103:12481-12486.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 7
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
    • Sen R, Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism. Cell. 1986;47:921-928.
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 8
    • 77953496625 scopus 로고    scopus 로고
    • The NF-kappaB family of transcription factors and its regulation
    • Oeckinghaus A, Ghosh S. The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol. 2009;1:a000034.
    • (2009) Cold Spring Harb Perspect Biol , pp. 1
    • Oeckinghaus, A.1    Ghosh, S.2
  • 9
    • 84858718448 scopus 로고    scopus 로고
    • NF-kappaB and the link between inflammation and cancer
    • DiDonato JA, Mercurio F, Karin M. NF-kappaB and the link between inflammation and cancer. Immunol Rev. 2012;246: 379-400.
    • (2012) Immunol Rev , vol.246 , pp. 379-400
    • Didonato, J.A.1    Mercurio, F.2    Karin, M.3
  • 10
    • 0142180047 scopus 로고    scopus 로고
    • Diabetesinduced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants
    • Kowluru RA, Koppolu P, Chakrabarti S, Chen S. Diabetesinduced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants. Free Radic Res. 2003; 37:1169-1180.
    • (2003) Free Radic Res , vol.37 , pp. 1169-1180
    • Kowluru, R.A.1    Koppolu, P.2    Chakrabarti, S.3    Chen, S.4
  • 11
    • 0035216928 scopus 로고    scopus 로고
    • Regulation of nuclear factor kappaB activation by Gprotein- coupled receptors
    • Ye RD. Regulation of nuclear factor kappaB activation by Gprotein- coupled receptors. J Leukoc Biol. 2001;70:839-848.
    • (2001) J Leukoc Biol , vol.70 , pp. 839-848
    • Ye, R.D.1
  • 12
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman AG. G proteins: transducers of receptor-generated signals. Annu Rev Biochem. 1987;56:615-649.
    • (1987) Annu Rev Biochem , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 13
    • 0033136318 scopus 로고    scopus 로고
    • Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion
    • Rahman A, Anwar KN, True AL, Malik AB. Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion. J Immunol. 1999;162:5466-5476.
    • (1999) J Immunol , vol.162 , pp. 5466-5476
    • Rahman, A.1    Anwar, K.N.2    True, A.L.3    Malik, A.B.4
  • 14
    • 0033524913 scopus 로고    scopus 로고
    • Lysophosphatidic acid activates NF-kappaB in fibroblasts. A requirement for multiple inputs
    • Shahrestanifar M, Fan X, Manning DR. Lysophosphatidic acid activates NF-kappaB in fibroblasts. A requirement for multiple inputs. J Biol Chem. 1999;274:3828-3833.
    • (1999) J Biol Chem , vol.274 , pp. 3828-3833
    • Shahrestanifar, M.1    Fan, X.2    Manning, D.R.3
  • 15
    • 0030950540 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme inhibition prevents arterial nuclear factorkappa B activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis
    • Hernandez-Presa M, Bustos C, Ortego M, et al. Angiotensinconverting enzyme inhibition prevents arterial nuclear factorkappa B activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis. Circulation. 1997;95:1532-1541.
    • (1997) Circulation , vol.95 , pp. 1532-1541
    • Hernandez-Presa, M.1    Bustos, C.2    Ortego, M.3
  • 16
    • 0032483171 scopus 로고    scopus 로고
    • Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2
    • Gallois C, Habib A, Tao J, et al. Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2. J Biol Chem. 1998;273:23183-23190.
    • (1998) J Biol Chem , vol.273 , pp. 23183-23190
    • Gallois, C.1    Habib, A.2    Tao, J.3
  • 17
    • 0032525398 scopus 로고    scopus 로고
    • Intestinal NF-kappaB is activated, mainly as p50 homodimers, by platelet-activating factor
    • De Plaen IG, Tan XD, Chang H, Qu XW, Liu QP, Hsueh W. Intestinal NF-kappaB is activated, mainly as p50 homodimers, by platelet-activating factor. Biochim Biophys Acta. 1998; 1392:185-192.
    • (1998) Biochim Biophys Acta , vol.1392 , pp. 185-192
    • de Plaen, I.G.1    Tan, X.D.2    Chang, H.3    Qu, X.W.4    Liu, Q.P.5    Hsueh, W.6
  • 18
    • 65249179023 scopus 로고    scopus 로고
    • CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex
    • Martin D, Galisteo R, Gutkind JS. CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex. J Biol Chem. 2009;284:6038-6042.
    • (2009) J Biol Chem , vol.284 , pp. 6038-6042
    • Martin, D.1    Galisteo, R.2    Gutkind, J.S.3
  • 19
    • 50649083968 scopus 로고    scopus 로고
    • SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NF-kappaB
    • Rehman AO, Wang CY. SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NF-kappaB. J Biol Chem. 2008;283:19888-19894.
    • (2008) J Biol Chem , vol.283 , pp. 19888-19894
    • Rehman, A.O.1    Wang, C.Y.2
  • 20
    • 35148898712 scopus 로고    scopus 로고
    • Suppression of diabetesinduced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway
    • Nagai N, Izumi-Nagai K, Oike Y, et al. Suppression of diabetesinduced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway. Invest Ophthalmol Vis Sci. 2007;48:4342-4350.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 4342-4350
    • Nagai, N.1    Izumi-Nagai, K.2    Oike, Y.3
  • 21
    • 0028051291 scopus 로고
    • Role of neutrophils in breakdown of the blood-retinal barrier following intravitreal injection of platelet-activating factor
    • Smith D, Lee EK, Saloupis P, Davis JK, Hatchell DL. Role of neutrophils in breakdown of the blood-retinal barrier following intravitreal injection of platelet-activating factor. Exp Eye Res. 1994;59:425-432.
    • (1994) Exp Eye Res , vol.59 , pp. 425-432
    • Smith, D.1    Lee, E.K.2    Saloupis, P.3    Davis, J.K.4    Hatchell, D.L.5
  • 22
    • 84879246903 scopus 로고    scopus 로고
    • Expression of lysophosphatidic acid, autotaxin and acylglycerol kinase as biomarkers in diabetic retinopathy
    • Abu El-Asrar AM, Mohammad G, Nawaz MI, Siddiquei MM, Kangave D, Opdenakker G. Expression of lysophosphatidic acid, autotaxin and acylglycerol kinase as biomarkers in diabetic retinopathy. Acta Diabetol. 2013;50:363-371.
    • (2013) Acta Diabetol , vol.50 , pp. 363-371
    • Abu El-Asrar, A.M.1    Mohammad, G.2    Nawaz, M.I.3    Siddiquei, M.M.4    Kangave, D.5    Opdenakker, G.6
  • 24
    • 84871250502 scopus 로고    scopus 로고
    • High vitreous concentration of IL-6 and IL-8, but not of adhesion molecules in relation to plasma concentrations in proliferative diabetic retinopathy
    • Koskela UE, Kuusisto SM, Nissinen AE, Savolainen MJ, Liinamaa MJ. High vitreous concentration of IL-6 and IL-8, but not of adhesion molecules in relation to plasma concentrations in proliferative diabetic retinopathy. Ophthalmic Res. 2013;49: 108-114.
    • (2013) Ophthalmic Res , vol.49 , pp. 108-114
    • Koskela, U.E.1    Kuusisto, S.M.2    Nissinen, A.E.3    Savolainen, M.J.4    Liinamaa, M.J.5
  • 25
    • 85047690920 scopus 로고    scopus 로고
    • SDF-1 is both necessary and sufficient to promote proliferative retinopathy
    • Butler JM, Guthrie SM, Koc M, et al. SDF-1 is both necessary and sufficient to promote proliferative retinopathy. J Clin Invest. 2005;115:86-93.
    • (2005) J Clin Invest , vol.115 , pp. 86-93
    • Butler, J.M.1    Guthrie, S.M.2    Koc, M.3
  • 26
    • 34250681374 scopus 로고    scopus 로고
    • CARD-Bcl10-Malt1 signalosomes: Missing link to NF-kappaB
    • Wegener E, Krappmann D. CARD-Bcl10-Malt1 signalosomes: missing link to NF-kappaB. Sci STKE. 2007:pe21.
    • (2007) Sci STKE
    • Wegener, E.1    Krappmann, D.2
  • 27
    • 34247240413 scopus 로고    scopus 로고
    • CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation
    • Grabiner BC, Blonska M, Lin PC, et al. CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation. Genes Dev. 2007;21:984-996.
    • (2007) Genes Dev , vol.21 , pp. 984-996
    • Grabiner, B.C.1    Blonska, M.2    Lin, P.C.3
  • 28
    • 0036187467 scopus 로고    scopus 로고
    • In vitro characterization of a spontaneously immortalized human M̈uller cell line (MIO-M1)
    • Limb GA, Salt TE, Munro PM, Moss SE, Khaw PT. In vitro characterization of a spontaneously immortalized human M̈uller cell line (MIO-M1). Invest Ophthalmol Vis Sci. 2002; 43:864-869.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 864-869
    • Limb, G.A.1    Salt, T.E.2    Munro, P.M.3    Moss, S.E.4    Khaw, P.T.5
  • 29
    • 34548329963 scopus 로고    scopus 로고
    • MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster
    • Xu S, Witmer PD, Lumayag S, Kovacs B, Valle D. MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster. J Biol Chem. 2007;282: 25053-25066.
    • (2007) J Biol Chem , vol.282 , pp. 25053-25066
    • Xu, S.1    Witmer, P.D.2    Lumayag, S.3    Kovacs, B.4    Valle, D.5
  • 30
    • 34249849671 scopus 로고    scopus 로고
    • A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration
    • Huang F, Mehta D, Predescu S, Kim KS, Lum H. A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration. Endothelium. 2007;14:25-34.
    • (2007) Endothelium , vol.14 , pp. 25-34
    • Huang, F.1    Mehta, D.2    Predescu, S.3    Kim, K.S.4    Lum, H.5
  • 31
    • 79960907123 scopus 로고    scopus 로고
    • Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells
    • O'Donnell JJ III, Zhuge Y, Holian O, et al. Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvasc Res. 2011;82: 105-112.
    • (2011) Microvasc Res , vol.82 , pp. 105-112
    • O'Donnell III, J.J.1    Zhuge, Y.2    Holian, O.3
  • 33
    • 0141565322 scopus 로고    scopus 로고
    • Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells
    • Lum H, Qiao J, Walter RJ, et al. Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells. Am J Physiol Heart Circ Physiol. 2003;285: H1786-H1789.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Lum, H.1    Qiao, J.2    Walter, R.J.3
  • 34
    • 0038172667 scopus 로고    scopus 로고
    • PKA inhibits RhoA activation: A protection mechanism against endothelial barrier dysfunction
    • Qiao J, Huang F, Lum H. PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol. 2003;284:L972-L980.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284
    • Qiao, J.1    Huang, F.2    Lum, H.3
  • 36
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu TK, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 1991;64:1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 37
    • 0037031487 scopus 로고    scopus 로고
    • Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells
    • Rahman A, True AL, Anwar KN, Ye RD, Voyno-Yasenetskaya TA, Malik AB. Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells. Circ Res. 2002;91: 398-405.
    • (2002) Circ Res , vol.91 , pp. 398-405
    • Rahman, A.1    True, A.L.2    Anwar, K.N.3    Ye, R.D.4    Voyno-Yasenetskaya, T.A.5    Malik, A.B.6
  • 38
    • 0025784847 scopus 로고
    • cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2{thorn} mobilization
    • Rasmussen UB, Vouret-Craviari V, Jallat S, et al. cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2{thorn} mobilization. FEBS Lett. 1991;288:123-128.
    • (1991) FEBS Lett , vol.288 , pp. 123-128
    • Rasmussen, U.B.1    Vouret-Craviari, V.2    Jallat, S.3
  • 39
    • 0037470077 scopus 로고    scopus 로고
    • Thrombin stimulation of vascular adhesion molecule-1 in endothelial cells is mediated by protein kinase C (PKC)-delta- NF-kappa B and PKC-zeta-GATA signaling pathways
    • Minami T, Abid MR, Zhang J, King G, Kodama T, Aird WC. Thrombin stimulation of vascular adhesion molecule-1 in endothelial cells is mediated by protein kinase C (PKC)-delta- NF-kappa B and PKC-zeta-GATA signaling pathways. J Biol Chem. 2003;278:6976-6984.
    • (2003) J Biol Chem , vol.278 , pp. 6976-6984
    • Minami, T.1    Abid, M.R.2    Zhang, J.3    King, G.4    Kodama, T.5    Aird, W.C.6
  • 40
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce JW, Schoenleber R, Jesmok G, et al. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem. 1997;272:21096-21103.
    • (1997) J Biol Chem , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3
  • 41
    • 84858722006 scopus 로고    scopus 로고
    • MicroRNAs, new effectors and regulators of NF-kappaB
    • Boldin MP, Baltimore D. MicroRNAs, new effectors and regulators of NF-kappaB. Immunol Rev. 2012;246:205-220.
    • (2012) Immunol Rev , vol.246 , pp. 205-220
    • Boldin, M.P.1    Baltimore, D.2
  • 42
    • 79551565924 scopus 로고    scopus 로고
    • MicroRNAs profiling in murine models of acute and chronic asthma: A relationship with mRNAs targets
    • Garbacki N, Di Valentin E, Huynh-Thu VA, et al. MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets. PLoS One. 2011;6:e16509.
    • (2011) PLoS One , vol.6
    • Garbacki, N.1    Di Valentin, E.2    Huynh-Thu, V.A.3
  • 44
    • 0029921450 scopus 로고    scopus 로고
    • Platelet-dependent thrombin generation in patients with diabetes mellitus: Effects of glycemic control on coagulability in diabetes
    • Aoki I, Shimoyama K, Aoki N, et al. Platelet-dependent thrombin generation in patients with diabetes mellitus: effects of glycemic control on coagulability in diabetes. J Am Coll Cardiol. 1996;27:560-566.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 560-566
    • Aoki, I.1    Shimoyama, K.2    Aoki, N.3
  • 46
    • 34249002721 scopus 로고    scopus 로고
    • Balancing focused combinatorial libraries based on multiple GPCR ligands
    • Soltanshahi F, Mansley TE, Choi S, Clark RD. Balancing focused combinatorial libraries based on multiple GPCR ligands. J Comput Aided Mol Des. 2006;20:529-538.
    • (2006) J Comput Aided Mol Des , vol.20 , pp. 529-538
    • Soltanshahi, F.1    Mansley, T.E.2    Choi, S.3    Clark, R.D.4
  • 47
    • 79952761245 scopus 로고    scopus 로고
    • CARMA3 is crucial for EGFRInduced activation of NF-kappaB and tumor progression
    • Jiang T, Grabiner B, Zhu Y, et al. CARMA3 is crucial for EGFRInduced activation of NF-kappaB and tumor progression. Cancer Res. 2011;71:2183-2192.
    • (2011) Cancer Res , vol.71 , pp. 2183-2192
    • Jiang, T.1    Grabiner, B.2    Zhu, Y.3
  • 48
    • 77953896432 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 2010;141:1117-1134.
    • (2010) Cell , vol.141 , pp. 1117-1134
    • Lemmon, M.A.1    Schlessinger, J.2
  • 49
    • 0025916059 scopus 로고
    • Micromotion of mammalian cells measured electrically
    • Giaever I, Keese CR. Micromotion of mammalian cells measured electrically. Proc Natl Acad Sci U S A. 1991;88: 7896-7900.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 7896-7900
    • Giaever, I.1    Keese, C.R.2
  • 50
    • 70549093110 scopus 로고    scopus 로고
    • Role of NF-kappaB in the pathogenesis of diabetes and its associated complications
    • Patel S, Santani D. Role of NF-kappaB in the pathogenesis of diabetes and its associated complications. Pharmacol Rep. 2009;61:595-603.
    • (2009) Pharmacol Rep , vol.61 , pp. 595-603
    • Patel, S.1    Santani, D.2
  • 51
    • 0025896795 scopus 로고
    • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis
    • Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991;251:788-791.
    • (1991) Science , vol.251 , pp. 788-791
    • Cybulsky, M.I.1    Gimbrone Jr., M.A.2


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