Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice

Autophagy

Volumn 12, Issue 12, 2016, Pages 2326-2343

  Han, Jihye ^a   Bae, Joonbeom ^a   Choi, Chang Yong ^a   Choi, Sang Pil ^a   Kang, Hyung Sik ^b   Jo, Eun Kyeong ^c   Park, Jongsun ^c   Lee, Young Sik ^a   Moon, Hyun Seuk ^a   Park, Chung Gyu ^d   Lee, Myung Shik ^e   Chun, Taehoon ^a  

^a Korea University   (South Korea)

^b Chonnam National University   (South Korea)

^c Chungnam National University   (South Korea)

^d Seoul National University College of Medicine   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

Author keywords

autophagy; AXL receptor tyrosine kinase; hepatic inflammation; macrophage; NLRP3 inflammasome

Indexed keywords

AUTOPHAGY RELATED PROTEIN 5; AXL RECEPTOR TYROSINE KINASE; BECLIN 1; CARBON TETRACHLORIDE; CRYOPYRIN; GROWTH ARREST SPECIFIC 6; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN; PROTEIN MAP1LC3B; PROTEIN TYROSINE KINASE; TYROSINE; UNCLASSIFIED DRUG; BECN1 PROTEIN, MOUSE; GROWTH ARREST-SPECIFIC PROTEIN 6; INFLAMMASOME; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NLRP3 PROTEIN, MOUSE; ONCOPROTEIN; PROTEIN BINDING; SIGNAL PEPTIDE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; AUTOPHOSPHORYLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GENE EXPRESSION; LIVER INJURY; LUNG ALVEOLUS MACROPHAGE; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CHEMISTRY; DEFICIENCY; ENZYMOLOGY; GENETICS; INJURIES; KUPFFER CELL; LIVER; MACROPHAGE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN DOMAIN;

ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; BECLIN-1; INFLAMMASOMES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-18; INTERLEUKIN-1BETA; KUPFFER CELLS; LIVER; MACROPHAGES; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 14; MODELS, BIOLOGICAL; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN DOMAINS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 85002823570     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1235124     Document Type: Article

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