Altered L-type Ca2+ channel activity contributes to exacerbated hypoperfusion and mortality in smooth muscle cell BK channel-deficient septic mice

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 307, Issue 2, 2014, Pages

  Xu, Hui ^a   Garver, Hannah ^a   Fernandes, Roxanne ^a   Galligan, James J ^a,b   Fink, Gregory D ^a,b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

BK 1 subunit knockout; Blood flow and tissue perfusion; Cytokines; Polymicrobial septic shock; Polymorphonuclear neutrophil infiltration and tissue injury

Indexed keywords

ANIMALS; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; DISEASE MODELS, ANIMAL; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BETA SUBUNITS; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; SEPSIS;

EID: 84904322404     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00117.2014     Document Type: Article

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