Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

Autophagy

Volumn 11, Issue 2, 2015, Pages 271-284

  Liu, Kun ^a   Zhao, Enpeng ^a   Ilyas, Ghulam ^a   Lalazar, Gadi ^a   Lin, Yu ^a   Haseeb, Muhammad ^a   Tanaka, Kathryn E ^b   Czaja, Mark J ^a,b  

^a MARION BESSIN LIVER RESEARCH CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Autophagy; Innate immunity; Kupffer cells; Lipopolysaccharide; Macrophage; Obesity; Polarization; Steatohepatitis

Indexed keywords

AUTOPHAGY PROTEIN 5; LIPOPOLYSACCHARIDE;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; BONE MARROW CELL; CELL POLARITY; CONTROLLED STUDY; EXPERIMENTAL STEATOHEPATITIS; IMMUNE RESPONSE; INFLAMMATION; KNOCKOUT MOUSE; KUPFFER CELL; LIPID DIET; LIVER INJURY; MALE; MOUSE; NONHUMAN; OBESITY; PERITONEUM MACROPHAGE; PHENOTYPE; ANIMAL; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; LIVER; MACROPHAGE; METABOLISM; MOUSE MUTANT; SIGNAL TRANSDUCTION;

ADIPOSE TISSUE; ANIMALS; AUTOPHAGY; CELL POLARITY; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; INFLAMMATION; LIVER; MACROPHAGES; MICE, KNOCKOUT; MICE, OBESE; OBESITY; SIGNAL TRANSDUCTION;

EID: 84927641793     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1009787     Document Type: Article

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