18α-Glycyrrhetinic acid proteasome activator decelerates aging and Alzheimer's disease progression in caenorhabditis elegans and neuronal cultures

Antioxidants and Redox Signaling

Volumn 25, Issue 16, 2016, Pages 855-869

  Papaevgeniou, Nikoletta ^a,b   Sakellari, Marianthi ^a,c   Jha, Sweta ^d   Tavernarakis, Nektarios ^e,f   Holmberg, Carina I ^d   Gonos, Efstathios S ^a,c   Chondrogianni, Niki ^a  

^a INSTITUTE OF BIOLOGY   (Greece)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c ÖREBRO UNIVERSITY   (Sweden)

^d UNIVERSITY OF HELSINKI   (Finland)

^e INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^f UNIVERSITY OF CRETE   (Greece)

Author keywords

aggregation; aging; Alzheimers disease; lifespan extension; proteasome activation; proteostasis

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; CATALASE; POLYUBIQUITIN; PROTEASOME; SUPEROXIDE; 18ALPHA-GLYCYRRHETINIC ACID; AMYLOID BETA PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; GLYCYRRHETINIC ACID;

ADULT; AGING; ALZHEIMER DISEASE; ARTICLE; CAENORHABDITIS ELEGANS; CELL SPECIFICITY; DISEASE COURSE; ENZYME ACTIVATION; GEL ELECTROPHORESIS; GENETIC MANIPULATION; HUMAN; HUMAN CELL; LIFE EXTENSION; NERVE CELL CULTURE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN HOMEOSTASIS; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA ISOLATION; SURVIVAL RATE; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; CELL DEATH; DRUG EFFECTS; LONGEVITY; METABOLISM; NERVE CELL; OXIDATION REDUCTION REACTION; PATHOLOGY; PHENOTYPE; PROTEINOSIS;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL DEATH; CELLS, CULTURED; DISEASE PROGRESSION; GLYCYRRHETINIC ACID; LONGEVITY; NEURONS; OXIDATION-REDUCTION; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN AGGREGATION, PATHOLOGICAL;

EID: 85002156990     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2015.6494     Document Type: Article

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