Employing alzheimer disease animal models for translational research: Focus on dietary components

Neurodegenerative Diseases

Volumn 13, Issue 2-3, 2014, Pages 131-134

  Grossi, Cristina ^a   Ed Dami, Teresa ^a   Rigacci, Stefania ^b   Stefani, Massimo ^b   Luccarini, Ilaria ^a   Casamenti, Fiorella ^a,b  

^a Department of Neuroscience Psychology Drug Research and Child Health   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Adult hippocampal neurogenesis; Autophagy; Oleuropein aglycone; TgCRND8 mice

Indexed keywords

AMYLOID BETA PROTEIN; OLEUROPEIN; OLEUROPEIN AGLYCONE; OLIVE OIL; POLYPHENOL; UNCLASSIFIED DRUG; VIRGIN OLIVE OIL;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; DIET SUPPLEMENTATION; DIET THERAPY; HIPPOCAMPUS; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSLATIONAL RESEARCH; BRAIN CORTEX; CONFERENCE PAPER; DIET; MEDITERRANEAN DIET;

ALZHEIMER DISEASE; ANIMAL FEED; ANIMALS; BRAIN; DIET, MEDITERRANEAN; DISEASE MODELS, ANIMAL; HUMANS; IRIDOIDS; MICE, TRANSGENIC; NEUROPROTECTIVE AGENTS; PLANT OILS; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84896718900     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000355461     Document Type: Article

References (16)

1. Casamenti F, Di Patre PL, Bartolini L, et al: Unilateral and bilateral nucleus basalis lesions: differences in neurochemical and behavioral recovery. Neuroscience 1988; 24: 209-215.
2. Giovannelli L, Casamenti F, Scali C, et al: Differential effects of amyloid peptides beta-(1-40) and beta-(25-35) injections into the rat nucleus basalis. Neuroscience 1995; 66: 781-792.
3. LaFerla FM, Green KN: Animal models of Alzheimer disease. Cold Spring Harb Perspect Med 2012; 2:a006320.
4. Rockenstein E, Crews L, Masliah E, et al: Transgenic animal models of neurodegenerative diseases and their application to treatment development. Adv Drug Deliv Rev 2007; 59: 1093-1102.
5. Paquet D, Schmid B, Haass C, et al: Transgenic Zebrafish as a novel animal model to study tauopathies and other neurodegenerative disorders in vivo. Neurodegener Dis 2010; 7: 99-102.
6. Cohen RM, Rezai-Zadeh K, Weitz TM, et al: A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric Aβ, and frank neuronal loss. J Neurosci 2013; 33: 6245-6256.
7. Zhang L, Chang RC, Chu LW, et al: Current neuroimaging techniques in Alzheimer's disease and applications in animal models. Am J Nucl Med Mol Imaging 2012; 2: 386-404.
8. Rubinsztein DC, Marino G, Kroemer G, et al: Autophagy and aging. Cell 2011; 146: 682-695.
9. Mizushima N, Komatsu M: Autophagy: renovation of cells and tissues. Cell 2011; 147: 728-741.
10. Ho L, Chen LH, Wang J, et al: Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's Disease-type neuropathology and cognitive deterioration. J Alzheimers Dis 2009; 16: 59-72.
11. Feart C, Samieri C, Rondeau V, et al: Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. JAMA 2009; 302: 638-648.
12. Pitozzi V, Jacomelli M, Zaid M, et al: Effects of dietary extra-virgin olive oil on behaviour and brain biochemical parameters in ageing rats. Br J Nutr 2010; 103: 1674-1683.
13. Karuppagounder SS, Pinto JT, Xu H, et al: Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int 2009; 54: 111-118.
14. Grossi C, Rigacci S, Ambrosini S, et al: The polyphenol oleuropein aglycone protects TgCRND8 mice against Aβ plaque pathology. PLoS One 2013; 8:e71702.
15. Bellucci A, Rosi MC, Grossi C, et al: Abnormal processing of tau in the brain of aged TgCRND8 mice. Neurobiol Dis 2007; 27: 328-338.
16. Fiorentini A, Rosi MC, Grossi C, et al: Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice. PLoS One 2010; 5:e14382.