Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis

FASEB Journal

Volumn 30, Issue 12, 2016, Pages 3997-4006

  Kalbitz, Miriam ^a,b   Fattahi, Fatemeh ^a   Grailer, Jamison J ^a   Jajou, Lawrence ^a   Malan, Elizabeth A ^a   Zetoune, Firas S ^a   Huber Lang, Markus ^b   Russell, Mark W ^a   Ward, Peter A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

C5a; C5a receptors; CLP; IL 1

Indexed keywords

COMPLEMENT COMPONENT C5A RECEPTOR; CRYOPYRIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; NIGERICIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; COMPLEMENT COMPONENT C5A; NLRP3 PROTEIN, MOUSE; NLRP3 PROTEIN, RAT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CARDIOMYOPATHY; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; DOPPLER ECHO; ECHOCARDIOGRAPHY; FLOW CYTOMETRY; FLUID RESUSCITATION; HEART; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; ANIMAL; METABOLISM; RAT; SEPSIS;

ANIMALS; COMPLEMENT C5A; INFLAMMASOMES; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICE; MITOCHONDRIA; MYOCYTES, CARDIAC; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RATS; REACTIVE OXYGEN SPECIES; SEPSIS;

EID: 85001967738     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201600728R     Document Type: Article

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