-
1
-
-
45549092607
-
Cancer immunology
-
COI: 1:CAS:528:DC%2BD1cXns1ajt7k%3D, PID: 18565863
-
Finn, O. J. (2008). Cancer immunology. The New England Journal of Medicine, 358(25), 2704–2715. doi:10.1056/NEJMra072739.
-
(2008)
The New England Journal of Medicine
, vol.358
, Issue.25
, pp. 2704-2715
-
-
Finn, O.J.1
-
2
-
-
78649430306
-
Trends in cancer immunotherapy
-
COI: 1:CAS:528:DC%2BC3cXpt1GlsL8%3D, PID: 20703326
-
Murphy, J. F. (2010). Trends in cancer immunotherapy. Clin Med Insights Oncol, 4, 67–80.
-
(2010)
Clin Med Insights Oncol
, vol.4
, pp. 67-80
-
-
Murphy, J.F.1
-
3
-
-
0033847587
-
Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma
-
PID: 10685660
-
Fisher, R. I., Rosenberg, S. A., & Fyfe, G. (2000). Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma. The Cancer Journal from Scientific American, 6(Suppl 1), S55–S57.
-
(2000)
The Cancer Journal from Scientific American
, vol.6
, pp. S55-S57
-
-
Fisher, R.I.1
Rosenberg, S.A.2
Fyfe, G.3
-
4
-
-
46749103710
-
Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
-
COI: 1:CAS:528:DC%2BD1cXosVynurk%3D, PID: 18620949
-
Eggermont, A. M., Suciu, S., Santinami, M., Testori, A., Kruit, W. H., Marsden, J., et al. (2008). Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet, 372(9633), 117–126. doi:10.1016/S0140-6736(08)61033-8.
-
(2008)
Lancet
, vol.372
, Issue.9633
, pp. 117-126
-
-
Eggermont, A.M.1
Suciu, S.2
Santinami, M.3
Testori, A.4
Kruit, W.H.5
Marsden, J.6
-
5
-
-
0028929682
-
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
-
COI: 1:STN:280:DyaK2M7ptVGiuw%3D%3D, PID: 7884429
-
Fyfe, G., Fisher, R. I., Rosenberg, S. A., Sznol, M., Parkinson, D. R., & Louie, A. C. (1995). Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. Journal of Clinical Oncology, 13(3), 688–696.
-
(1995)
Journal of Clinical Oncology
, vol.13
, Issue.3
, pp. 688-696
-
-
Fyfe, G.1
Fisher, R.I.2
Rosenberg, S.A.3
Sznol, M.4
Parkinson, D.R.5
Louie, A.C.6
-
6
-
-
65549091573
-
Cell death mechanisms induced by cytotoxic lymphocytes
-
COI: 1:CAS:528:DC%2BD1MXktFGksrs%3D
-
Chavez-Galan, L., Arenas-Del Angel, M. C., Zenteno, E., Chavez, R., & Lascurain, R. (2009). Cell death mechanisms induced by cytotoxic lymphocytes. Cellular & Molecular Immunology, 6(1), 15–25. doi:10.1038/cmi.2009.3.
-
(2009)
Cellular & Molecular Immunology
, vol.6
, Issue.1
, pp. 15-25
-
-
Chavez-Galan, L.1
Arenas-Del Angel, M.C.2
Zenteno, E.3
Chavez, R.4
Lascurain, R.5
-
7
-
-
37549036732
-
Fcgamma receptors as regulators of immune responses
-
COI: 1:CAS:528:DC%2BD2sXhsVKrsLnK, PID: 18064051
-
Nimmerjahn, F., & Ravetch, J. V. (2008). Fcgamma receptors as regulators of immune responses. Nature Reviews. Immunology, 8(1), 34–47. doi:10.1038/nri2206.
-
(2008)
Nature Reviews. Immunology
, vol.8
, Issue.1
, pp. 34-47
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
8
-
-
84958523290
-
Fc receptor-dependent mechanisms of monoclonal antibody therapy of cancer
-
COI: 1:CAS:528:DC%2BC2MXnt1Cqt7o%3D, PID: 25116109
-
Bakema, J. E., & van Egmond, M. (2014). Fc receptor-dependent mechanisms of monoclonal antibody therapy of cancer. Current Topics in Microbiology and Immunology, 382, 373–392. doi:10.1007/978-3-319-07911-0_17.
-
(2014)
Current Topics in Microbiology and Immunology
, vol.382
, pp. 373-392
-
-
Bakema, J.E.1
van Egmond, M.2
-
9
-
-
84901463516
-
Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies - impact of effector cells
-
COI: 1:CAS:528:DC%2BC2cXmsVChtL8%3D, PID: 24704820
-
Chung, S., Lin, Y. L., Reed, C., Ng, C., Cheng, Z. J., Malavasi, F., et al. (2014). Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies - impact of effector cells. Journal of Immunological Methods, 407, 63–75. doi:10.1016/j.jim.2014.03.021.
-
(2014)
Journal of Immunological Methods
, vol.407
, pp. 63-75
-
-
Chung, S.1
Lin, Y.L.2
Reed, C.3
Ng, C.4
Cheng, Z.J.5
Malavasi, F.6
-
10
-
-
65349119978
-
CD28 and CTLA-4 coreceptor expression and signal transduction
-
COI: 1:CAS:528:DC%2BD1MXhsFGls7jN, PID: 19426212
-
Rudd, C. E., Taylor, A., & Schneider, H. (2009). CD28 and CTLA-4 coreceptor expression and signal transduction. Immunological Reviews, 229(1), 12–26. doi:10.1111/j.1600-065X.2009.00770.x.
-
(2009)
Immunological Reviews
, vol.229
, Issue.1
, pp. 12-26
-
-
Rudd, C.E.1
Taylor, A.2
Schneider, H.3
-
11
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
COI: 1:CAS:528:DC%2BC38XksVegtrw%3D, PID: 22437870
-
Pardoll, D. M. (2012). The blockade of immune checkpoints in cancer immunotherapy. Nature Reviews. Cancer, 12(4), 252–264. doi:10.1038/nrc3239.
-
(2012)
Nature Reviews. Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
12
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
COI: 1:CAS:528:DC%2BD1cXht1Slu7%2FJ, PID: 18845758
-
Wing, K., Onishi, Y., Prieto-Martin, P., Yamaguchi, T., Miyara, M., Fehervari, Z., et al. (2008). CTLA-4 control over Foxp3+ regulatory T cell function. Science, 322(5899), 271–275. doi:10.1126/science.1160062.
-
(2008)
Science
, vol.322
, Issue.5899
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
-
13
-
-
68149155982
-
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
-
COI: 1:CAS:528:DC%2BD1MXps1enu7w%3D, PID: 19581407
-
Peggs, K. S., Quezada, S. A., Chambers, C. A., Korman, A. J., & Allison, J. P. (2009). Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. The Journal of Experimental Medicine, 206(8), 1717–1725. doi:10.1084/jem.20082492.
-
(2009)
The Journal of Experimental Medicine
, vol.206
, Issue.8
, pp. 1717-1725
-
-
Peggs, K.S.1
Quezada, S.A.2
Chambers, C.A.3
Korman, A.J.4
Allison, J.P.5
-
14
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
COI: 1:CAS:528:DC%2BC3cXhtVCrtrbN, PID: 20525992
-
Hodi, F. S., O'Day, S. J., McDermott, D. F., Weber, R. W., Sosman, J. A., Haanen, J. B., et al. (2010). Improved survival with ipilimumab in patients with metastatic melanoma. The New England Journal of Medicine, 363(8), 711–723. doi:10.1056/NEJMoa1003466.
-
(2010)
The New England Journal of Medicine
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
15
-
-
84884271914
-
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma
-
COI: 1:CAS:528:DC%2BC3sXhsVSgsbrL, PID: 23897981
-
Simpson, T. R., Li, F., Montalvo-Ortiz, W., Sepulveda, M. A., Bergerhoff, K., Arce, F., et al. (2013). Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma. The Journal of Experimental Medicine, 210(9), 1695–1710. doi:10.1084/jem.20130579.
-
(2013)
The Journal of Experimental Medicine
, vol.210
, Issue.9
, pp. 1695-1710
-
-
Simpson, T.R.1
Li, F.2
Montalvo-Ortiz, W.3
Sepulveda, M.A.4
Bergerhoff, K.5
Arce, F.6
-
16
-
-
84884229186
-
Activating Fc gamma receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies
-
COI: 1:CAS:528:DC%2BC3sXhsVSgsbrJ, PID: 23897982
-
Bulliard, Y., Jolicoeur, R., Windman, M., Rue, S. M., Ettenberg, S., Knee, D. A., et al. (2013). Activating Fc gamma receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies. The Journal of Experimental Medicine, 210(9), 1685–1693. doi:10.1084/jem.20130573.
-
(2013)
The Journal of Experimental Medicine
, vol.210
, Issue.9
, pp. 1685-1693
-
-
Bulliard, Y.1
Jolicoeur, R.2
Windman, M.3
Rue, S.M.4
Ettenberg, S.5
Knee, D.A.6
-
17
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
COI: 1:CAS:528:DC%2BC3sXjvVart74%3D, PID: 23295794
-
Ribas, A., Kefford, R., Marshall, M. A., Punt, C. J., Haanen, J. B., Marmol, M., et al. (2013). Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. Journal of Clinical Oncology, 31(5), 616–622. doi:10.1200/JCO.2012.44.6112.
-
(2013)
Journal of Clinical Oncology
, vol.31
, Issue.5
, pp. 616-622
-
-
Ribas, A.1
Kefford, R.2
Marshall, M.A.3
Punt, C.J.4
Haanen, J.B.5
Marmol, M.6
-
18
-
-
77954230122
-
Tremelimumab in combination with exemestane in patients with advanced breast cancer and treatment-associated modulation of inducible costimulator expression on patient T cells
-
COI: 1:CAS:528:DC%2BC3cXot1WltrY%3D, PID: 20479064
-
Vonderheide, R. H., LoRusso, P. M., Khalil, M., Gartner, E. M., Khaira, D., Soulieres, D., et al. (2010). Tremelimumab in combination with exemestane in patients with advanced breast cancer and treatment-associated modulation of inducible costimulator expression on patient T cells. Clinical Cancer Research, 16(13), 3485–3494. doi:10.1158/1078-0432.CCR-10-0505.
-
(2010)
Clinical Cancer Research
, vol.16
, Issue.13
, pp. 3485-3494
-
-
Vonderheide, R.H.1
LoRusso, P.M.2
Khalil, M.3
Gartner, E.M.4
Khaira, D.5
Soulieres, D.6
-
19
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
COI: 1:CAS:528:DC%2BD1cXltlWktrY%3D, PID: 18173375
-
Keir, M. E., Butte, M. J., Freeman, G. J., & Sharpe, A. H. (2008). PD-1 and its ligands in tolerance and immunity. Annual Review of Immunology, 26, 677–704. doi:10.1146/annurev.immunol.26.021607.090331.
-
(2008)
Annual Review of Immunology
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
20
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
COI: 1:CAS:528:DC%2BD1MXhtFygsLjL, PID: 19783989
-
Fife, B. T., Pauken, K. E., Eagar, T. N., Obu, T., Wu, J., Tang, Q., et al. (2009). Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nature Immunology, 10(11), 1185–1192. doi:10.1038/ni.1790.
-
(2009)
Nature Immunology
, vol.10
, Issue.11
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
Obu, T.4
Wu, J.5
Tang, Q.6
-
21
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
COI: 1:CAS:528:DC%2BD28XhtFyktL0%3D, PID: 16382236
-
Barber, D. L., Wherry, E. J., Masopust, D., Zhu, B., Allison, J. P., Sharpe, A. H., et al. (2006). Restoring function in exhausted CD8 T cells during chronic viral infection. Nature, 439(7077), 682–687. doi:10.1038/nature04444.
-
(2006)
Nature
, vol.439
, Issue.7077
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
-
22
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
COI: 1:CAS:528:DC%2BD3cXntFSlt7o%3D, PID: 11015443
-
Freeman, G. J., Long, A. J., Iwai, Y., Bourque, K., Chernova, T., Nishimura, H., et al. (2000). Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. The Journal of Experimental Medicine, 192(7), 1027–1034.
-
(2000)
The Journal of Experimental Medicine
, vol.192
, Issue.7
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
-
23
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
COI: 1:CAS:528:DC%2BD1MXhtVyiur3K, PID: 19423728
-
Ahmadzadeh, M., Johnson, L. A., Heemskerk, B., Wunderlich, J. R., Dudley, M. E., White, D. E., et al. (2009). Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood, 114(8), 1537–1544. doi:10.1182/blood-2008-12-195792.
-
(2009)
Blood
, vol.114
, Issue.8
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
Johnson, L.A.2
Heemskerk, B.3
Wunderlich, J.R.4
Dudley, M.E.5
White, D.E.6
-
24
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
-
COI: 1:CAS:528:DC%2BD38Xls12msLo%3D, PID: 12091876
-
Dong, H., Strome, S. E., Salomao, D. R., Tamura, H., Hirano, F., Flies, D. B., et al. (2002). Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nature Medicine, 8(8), 793–800. doi:10.1038/nm730.
-
(2002)
Nature Medicine
, vol.8
, Issue.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
-
25
-
-
84859128199
-
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
-
Taube, J. M., Anders, R. A., Young, G. D., Xu, H., Sharma, R., McMiller, T. L., et al. (2012). Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Science Translational Medicine, 4(127), 127ra137. doi:10.1126/scitranslmed.3003689.
-
(2012)
Science Translational Medicine
, vol.4
, Issue.127
, pp. 127ra137
-
-
Taube, J.M.1
Anders, R.A.2
Young, G.D.3
Xu, H.4
Sharma, R.5
McMiller, T.L.6
-
26
-
-
84879795618
-
The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer
-
COI: 1:CAS:528:DC%2BC3sXhtVGksbvJ, PID: 23756627
-
Muenst, S., Soysal, S. D., Gao, F., Obermann, E. C., Oertli, D., & Gillanders, W. E. (2013). The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer. Breast Cancer Research and Treatment, 139(3), 667–676. doi:10.1007/s10549-013-2581-3.
-
(2013)
Breast Cancer Research and Treatment
, vol.139
, Issue.3
, pp. 667-676
-
-
Muenst, S.1
Soysal, S.D.2
Gao, F.3
Obermann, E.C.4
Oertli, D.5
Gillanders, W.E.6
-
27
-
-
33646367200
-
The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors
-
COI: 1:CAS:528:DC%2BD28XovVKlurs%3D, PID: 16611412
-
Ghebeh, H., Mohammed, S., Al-Omair, A., Qattan, A., Lehe, C., Al-Qudaihi, G., et al. (2006). The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors. Neoplasia, 8(3), 190–198. doi:10.1593/neo.05733.
-
(2006)
Neoplasia
, vol.8
, Issue.3
, pp. 190-198
-
-
Ghebeh, H.1
Mohammed, S.2
Al-Omair, A.3
Qattan, A.4
Lehe, C.5
Al-Qudaihi, G.6
-
28
-
-
84925002847
-
Prognostic and predictive value of PDL1 expression in breast cancer
-
PID: 25669979
-
Sabatier, R., Finetti, P., Mamessier, E., Adelaide, J., Chaffanet, M., Ali, H. R., et al. (2015). Prognostic and predictive value of PDL1 expression in breast cancer. Oncotarget, 6(7), 5449–5464.
-
(2015)
Oncotarget
, vol.6
, Issue.7
, pp. 5449-5464
-
-
Sabatier, R.1
Finetti, P.2
Mamessier, E.3
Adelaide, J.4
Chaffanet, M.5
Ali, H.R.6
-
29
-
-
84902582266
-
PD-L1 expression in triple-negative breast cancer
-
COI: 1:CAS:528:DC%2BC2cXlvFWgsb4%3D, PID: 24764583
-
Mittendorf, E. A., Philips, A. V., Meric-Bernstam, F., Qiao, N., Wu, Y., Harrington, S., et al. (2014). PD-L1 expression in triple-negative breast cancer. Cancer Immunology Research, 2(4), 361–370. doi:10.1158/2326-6066.CIR-13-0127.
-
(2014)
Cancer Immunology Research
, vol.2
, Issue.4
, pp. 361-370
-
-
Mittendorf, E.A.1
Philips, A.V.2
Meric-Bernstam, F.3
Qiao, N.4
Wu, Y.5
Harrington, S.6
-
30
-
-
84919385463
-
Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type
-
COI: 1:CAS:528:DC%2BC2cXitVGrsrrN
-
Gatalica, Z., Snyder, C., Maney, T., Ghazalpour, A., Holterman, D. A., Xiao, N., et al. (2014). Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type. Cancer Epidemiology, Biomarkers & Prevention, 23(12), 2965–2970. doi:10.1158/1055-9965.EPI-14-0654.
-
(2014)
Cancer Epidemiology, Biomarkers & Prevention
, vol.23
, Issue.12
, pp. 2965-2970
-
-
Gatalica, Z.1
Snyder, C.2
Maney, T.3
Ghazalpour, A.4
Holterman, D.A.5
Xiao, N.6
-
31
-
-
37349014037
-
Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis
-
COI: 1:CAS:528:DC%2BD1cXhtF2ltg%3D%3D, PID: 17920123
-
Zhang, P., Su, D. M., Liang, M., & Fu, J. (2008). Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis. Molecular Immunology, 45(5), 1470–1476. doi:10.1016/j.molimm.2007.08.013.
-
(2008)
Molecular Immunology
, vol.45
, Issue.5
, pp. 1470-1476
-
-
Zhang, P.1
Su, D.M.2
Liang, M.3
Fu, J.4
-
32
-
-
84983370835
-
PD-L1 expression correlates with tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy in breast cancer
-
COI: 1:CAS:528:DC%2BC2MXlvFemtLo%3D, PID: 25527356
-
Wimberly, H., Brown, J. R., Schalper, K., Haack, H., Silver, M. R., Nixon, C., et al. (2015). PD-L1 expression correlates with tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy in breast cancer. Cancer Immunology Research, 3(4), 326–332. doi:10.1158/2326-6066.CIR-14-0133.
-
(2015)
Cancer Immunology Research
, vol.3
, Issue.4
, pp. 326-332
-
-
Wimberly, H.1
Brown, J.R.2
Schalper, K.3
Haack, H.4
Silver, M.R.5
Nixon, C.6
-
33
-
-
84863602592
-
Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies
-
COI: 1:CAS:528:DC%2BC38XpsFKktL0%3D, PID: 22570253
-
Verbrugge, I., Hagekyriakou, J., Sharp, L. L., Galli, M., West, A., McLaughlin, N. M., et al. (2012). Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies. Cancer Research, 72(13), 3163–3174. doi:10.1158/0008-5472.CAN-12-0210.
-
(2012)
Cancer Research
, vol.72
, Issue.13
, pp. 3163-3174
-
-
Verbrugge, I.1
Hagekyriakou, J.2
Sharp, L.L.3
Galli, M.4
West, A.5
McLaughlin, N.M.6
-
34
-
-
84879783148
-
Blockade of PD-1/PD-L1 immune checkpoint during DC vaccination induces potent protective immunity against breast cancer in hu-SCID mice
-
COI: 1:CAS:528:DC%2BC3sXlsFCgt74%3D, PID: 23523609
-
Ge, Y., Xi, H., Ju, S., & Zhang, X. (2013). Blockade of PD-1/PD-L1 immune checkpoint during DC vaccination induces potent protective immunity against breast cancer in hu-SCID mice. Cancer Letters, 336(2), 253–259. doi:10.1016/j.canlet.2013.03.010.
-
(2013)
Cancer Letters
, vol.336
, Issue.2
, pp. 253-259
-
-
Ge, Y.1
Xi, H.2
Ju, S.3
Zhang, X.4
-
35
-
-
79955570584
-
Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
-
COI: 1:CAS:528:DC%2BC3MXlslyqt7w%3D, PID: 21482773
-
Stagg, J., Loi, S., Divisekera, U., Ngiow, S. F., Duret, H., Yagita, H., et al. (2011). Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy. Proceedings of the National Academy of Sciences of the United States of America, 108(17), 7142–7147. doi:10.1073/pnas.1016569108.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.17
, pp. 7142-7147
-
-
Stagg, J.1
Loi, S.2
Divisekera, U.3
Ngiow, S.F.4
Duret, H.5
Yagita, H.6
-
36
-
-
84895904745
-
Mitigating the toxic effects of anticancer immunotherapy
-
COI: 1:CAS:528:DC%2BC2cXhtVOrurg%3D, PID: 24445516
-
Gangadhar, T. C., & Vonderheide, R. H. (2014). Mitigating the toxic effects of anticancer immunotherapy. Nature Reviews. Clinical Oncology, 11(2), 91–99. doi:10.1038/nrclinonc.2013.245.
-
(2014)
Nature Reviews. Clinical Oncology
, vol.11
, Issue.2
, pp. 91-99
-
-
Gangadhar, T.C.1
Vonderheide, R.H.2
-
37
-
-
84902659459
-
Breast cancer immunotherapy: monoclonal antibodies and peptide-based vaccines
-
COI: 1:CAS:528:DC%2BC2cXpslyntb8%3D, PID: 24867051
-
Mohit, E., Hashemi, A., & Allahyari, M. (2014). Breast cancer immunotherapy: monoclonal antibodies and peptide-based vaccines. Expert Review of Clinical Immunology, 10(7), 927–961. doi:10.1586/1744666X.2014.916211.
-
(2014)
Expert Review of Clinical Immunology
, vol.10
, Issue.7
, pp. 927-961
-
-
Mohit, E.1
Hashemi, A.2
Allahyari, M.3
-
38
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
-
COI: 1:CAS:528:DC%2BC2MXkvVWgsLk%3D, PID: 25795410
-
Weber, J. S., D'Angelo, S. P., Minor, D., Hodi, F. S., Gutzmer, R., Neyns, B., et al. (2015). Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. The Lancet Oncology, 16(4), 375–384. doi:10.1016/S1470-2045(15)70076-8.
-
(2015)
The Lancet Oncology
, vol.16
, Issue.4
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
Hodi, F.S.4
Gutzmer, R.5
Neyns, B.6
-
39
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
COI: 1:CAS:528:DC%2BC2MXht12qu7%2FJ, PID: 26028407
-
Brahmer, J., Reckamp, K. L., Baas, P., Crino, L., Eberhardt, W. E., Poddubskaya, E., et al. (2015). Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. The New England Journal of Medicine, 373(2), 123–135. doi:10.1056/NEJMoa1504627.
-
(2015)
The New England Journal of Medicine
, vol.373
, Issue.2
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crino, L.4
Eberhardt, W.E.5
Poddubskaya, E.6
-
40
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
COI: 1:CAS:528:DC%2BC28XjsFyhsrg%3D, PID: 26406148
-
Motzer, R. J., Escudier, B., McDermott, D. F., George, S., Hammers, H. J., Srinivas, S., et al. (2015). Nivolumab versus everolimus in advanced renal-cell carcinoma. The New England Journal of Medicine, 373(19), 1803–1813. doi:10.1056/NEJMoa1510665.
-
(2015)
The New England Journal of Medicine
, vol.373
, Issue.19
, pp. 1803-1813
-
-
Motzer, R.J.1
Escudier, B.2
McDermott, D.F.3
George, S.4
Hammers, H.J.5
Srinivas, S.6
-
41
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
COI: 1:CAS:528:DC%2BC2cXhtFGlsb%2FN, PID: 25034862
-
Robert, C., Ribas, A., Wolchok, J. D., Hodi, F. S., Hamid, O., Kefford, R., et al. (2014). Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet, 384(9948), 1109–1117. doi:10.1016/S0140-6736(14)60958-2.
-
(2014)
Lancet
, vol.384
, Issue.9948
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
Hodi, F.S.4
Hamid, O.5
Kefford, R.6
-
42
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
PID: 25891174
-
Garon, E. B., Rizvi, N. A., Hui, R., Leighl, N., Balmanoukian, A. S., Eder, J. P., et al. (2015). Pembrolizumab for the treatment of non-small-cell lung cancer. The New England Journal of Medicine, 372(21), 2018–2028. doi:10.1056/NEJMoa1501824.
-
(2015)
The New England Journal of Medicine
, vol.372
, Issue.21
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
Leighl, N.4
Balmanoukian, A.S.5
Eder, J.P.6
-
43
-
-
85008364745
-
Abstract S1-09: A phase Ib study of pembrolizumab (MK-3475) in patients with advanced triple-negative breast cancer. Cancer Res, 75(9 Supplement)
-
Nanda, R., Chow, L. Q., Dees, E. C., Berger, R., Gupta, S., Geva, R., et al. (2015). Abstract S1-09: A phase Ib study of pembrolizumab (MK-3475) in patients with advanced triple-negative breast cancer. Cancer Res, 75(9 Supplement), S1-09-S01-09.
-
(2015)
S1-09-S01-09
-
-
Nanda, R.1
Chow, L.Q.2
Dees, E.C.3
Berger, R.4
Gupta, S.5
Geva, R.6
-
44
-
-
85008368863
-
Abstract S5-07: Preliminary efficacy and safety of pembrolizumab (MK-3475) in patients with PD-L1–positive, estrogen receptor-positive (ER+)/HER2-negative advanced breast cancer enrolled in KEYNOTE-028. Cancer Res, 76(4 Supplement)
-
Rugo, H., Delord, J., Im, S., Ott, P., Piha-Paul, S., Bedard, P., et al. (2016). Abstract S5-07: Preliminary efficacy and safety of pembrolizumab (MK-3475) in patients with PD-L1–positive, estrogen receptor-positive (ER+)/HER2-negative advanced breast cancer enrolled in KEYNOTE-028. Cancer Res, 76(4 Supplement), S5-07-S05-07.
-
(2016)
S5-07-S05-07
-
-
Rugo, H.1
Delord, J.2
Im, S.3
Ott, P.4
Piha-Paul, S.5
Bedard, P.6
-
45
-
-
84929378787
-
Immune targeting in breast cancer
-
Cimino-Mathews, A., Foote, J. B., & Emens, L. A. (2015). Immune targeting in breast cancer. Oncology (Williston Park), 29(5), 375–385.
-
(2015)
Oncology (Williston Park)
, vol.29
, Issue.5
, pp. 375-385
-
-
Cimino-Mathews, A.1
Foote, J.B.2
Emens, L.A.3
-
46
-
-
85008332949
-
Abstract PD1-6: Inhibition of PD-L1 by MPDL3280A leads to clinical activity in patients with metastatic triple-negative breast cancer. Cancer Res, 75(9 Supplement)
-
Emens, L. A., Braiteh, F. S., Cassier, P., DeLord, J.-P., Eder, J. P., Shen, X., et al. (2015). Abstract PD1-6: Inhibition of PD-L1 by MPDL3280A leads to clinical activity in patients with metastatic triple-negative breast cancer. Cancer Res, 75(9 Supplement), PD1-6-PD1-6.
-
(2015)
PD1-6-PD1-6
-
-
Emens, L.A.1
Braiteh, F.S.2
Cassier, P.3
DeLord, J.-P.4
Eder, J.P.5
Shen, X.6
-
47
-
-
85008399308
-
-
Adams S, D. J., Hamilton E, et al. (December 8–12, 2015). Safety and clinical activity of atezolizumab (anti-PDL1) in combination with nab-paclitaxel in patients with metastatic triple-negative breast cancer. Presented at: San Antonio Breast Cancer Symposium; San Antonio, TX.
-
Adams S, D. J., Hamilton E, et al. (December 8–12, 2015). Safety and clinical activity of atezolizumab (anti-PDL1) in combination with nab-paclitaxel in patients with metastatic triple-negative breast cancer. Presented at: San Antonio Breast Cancer Symposium; San Antonio, TX.
-
-
-
-
48
-
-
85008348850
-
Abstract S1-04: Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: A phase Ib JAVELIN solid tumor trial. Cancer Res, 76(4 Supplement)
-
Dirix, L., Takacs, I., Nikolinakos, P., Jerusalem, G., Arkenau, H., Hamilton, E., et al. (2016). Abstract S1-04: Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: A phase Ib JAVELIN solid tumor trial. Cancer Res, 76(4 Supplement), S1-04-S01-04.
-
(2016)
S1-04-S01-04
-
-
Dirix, L.1
Takacs, I.2
Nikolinakos, P.3
Jerusalem, G.4
Arkenau, H.5
Hamilton, E.6
-
49
-
-
84871483917
-
Breast cancer immunobiology driving immunotherapy: vaccines and immune checkpoint blockade
-
COI: 1:CAS:528:DC%2BC38XhvVGmtb%2FN, PID: 23253225
-
Emens, L. A. (2012). Breast cancer immunobiology driving immunotherapy: vaccines and immune checkpoint blockade. Expert Review of Anticancer Therapy, 12(12), 1597–1611. doi:10.1586/era.12.147.
-
(2012)
Expert Review of Anticancer Therapy
, vol.12
, Issue.12
, pp. 1597-1611
-
-
Emens, L.A.1
-
50
-
-
73949092850
-
Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
-
COI: 1:CAS:528:DC%2BC3cXhtF2rsro%3D, PID: 19917869
-
Denkert, C., Loibl, S., Noske, A., Roller, M., Muller, B. M., Komor, M., et al. (2010). Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. Journal of Clinical Oncology, 28(1), 105–113. doi:10.1200/JCO.2009.23.7370.
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.1
, pp. 105-113
-
-
Denkert, C.1
Loibl, S.2
Noske, A.3
Roller, M.4
Muller, B.M.5
Komor, M.6
-
51
-
-
82955217260
-
Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
-
COI: 1:CAS:528:DC%2BC38XhvVykt70%3D, PID: 22151962
-
West, N. R., Milne, K., Truong, P. T., Macpherson, N., Nelson, B. H., & Watson, P. H. (2011). Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer. Breast Cancer Research, 13(6), R126. doi:10.1186/bcr3072.
-
(2011)
Breast Cancer Research
, vol.13
, Issue.6
, pp. R126
-
-
West, N.R.1
Milne, K.2
Truong, P.T.3
Macpherson, N.4
Nelson, B.H.5
Watson, P.H.6
-
52
-
-
79958189573
-
In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival
-
COI: 1:CAS:528:DC%2BC3MXntVGmsbw%3D, PID: 21437909
-
Ladoire, S., Mignot, G., Dabakuyo, S., Arnould, L., Apetoh, L., Rebe, C., et al. (2011). In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival. The Journal of Pathology, 224(3), 389–400. doi:10.1002/path.2866.
-
(2011)
The Journal of Pathology
, vol.224
, Issue.3
, pp. 389-400
-
-
Ladoire, S.1
Mignot, G.2
Dabakuyo, S.3
Arnould, L.4
Apetoh, L.5
Rebe, C.6
-
53
-
-
82155171374
-
Biological functions of regulatory T cells
-
PID: 22118408
-
Shevach, E. M. (2011). Biological functions of regulatory T cells. Advances in Immunology, 112, 137–176. doi:10.1016/B978-0-12-387827-4.00004-8.
-
(2011)
Advances in Immunology
, vol.112
, pp. 137-176
-
-
Shevach, E.M.1
-
54
-
-
84893065836
-
Harnessing the immune system for the treatment of breast cancer
-
COI: 1:CAS:528:DC%2BC2cXisVCrtb0%3D, PID: 24390741
-
Jiang, X. (2014). Harnessing the immune system for the treatment of breast cancer. Journal of Zhejiang University. Science. B, 15(1), 1–15. doi:10.1631/jzus.B1300264.
-
(2014)
Journal of Zhejiang University. Science. B
, vol.15
, Issue.1
, pp. 1-15
-
-
Jiang, X.1
-
55
-
-
34247261531
-
Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
-
PID: 17135638
-
Bates, G. J., Fox, S. B., Han, C., Leek, R. D., Garcia, J. F., Harris, A. L., et al. (2006). Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. Journal of Clinical Oncology, 24(34), 5373–5380. doi:10.1200/JCO.2006.05.9584.
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.34
, pp. 5373-5380
-
-
Bates, G.J.1
Fox, S.B.2
Han, C.3
Leek, R.D.4
Garcia, J.F.5
Harris, A.L.6
-
56
-
-
56649102194
-
Immunosuppressive regulatory T cells are associated with aggressive breast cancer phenotypes: a potential therapeutic target
-
COI: 1:CAS:528:DC%2BD1cXhsVSjsbzE, PID: 18820666
-
Bohling, S. D., & Allison, K. H. (2008). Immunosuppressive regulatory T cells are associated with aggressive breast cancer phenotypes: a potential therapeutic target. Modern Pathology, 21(12), 1527–1532. doi:10.1038/modpathol.2008.160.
-
(2008)
Modern Pathology
, vol.21
, Issue.12
, pp. 1527-1532
-
-
Bohling, S.D.1
Allison, K.H.2
-
57
-
-
62449250053
-
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome
-
COI: 1:CAS:528:DC%2BD1MXisFSrtbg%3D, PID: 19244125
-
Gobert, M., Treilleux, I., Bendriss-Vermare, N., Bachelot, T., Goddard-Leon, S., Arfi, V., et al. (2009). Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Research, 69(5), 2000–2009. doi:10.1158/0008-5472.CAN-08-2360.
-
(2009)
Cancer Research
, vol.69
, Issue.5
, pp. 2000-2009
-
-
Gobert, M.1
Treilleux, I.2
Bendriss-Vermare, N.3
Bachelot, T.4
Goddard-Leon, S.5
Arfi, V.6
-
58
-
-
79956131523
-
Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4(+) T cells to T-regulatory cells
-
COI: 1:CAS:528:DC%2BC3MXmtVGlt7w%3D, PID: 21444674
-
Olkhanud, P. B., Damdinsuren, B., Bodogai, M., Gress, R. E., Sen, R., Wejksza, K., et al. (2011). Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4(+) T cells to T-regulatory cells. Cancer Research, 71(10), 3505–3515. doi:10.1158/0008-5472.CAN-10-4316.
-
(2011)
Cancer Research
, vol.71
, Issue.10
, pp. 3505-3515
-
-
Olkhanud, P.B.1
Damdinsuren, B.2
Bodogai, M.3
Gress, R.E.4
Sen, R.5
Wejksza, K.6
-
59
-
-
76749135760
-
Antiestrogens induce transforming growth factor beta-mediated immunosuppression in breast cancer
-
COI: 1:CAS:528:DC%2BC3cXhvFaks74%3D, PID: 20145137
-
Joffroy, C. M., Buck, M. B., Stope, M. B., Popp, S. L., Pfizenmaier, K., & Knabbe, C. (2010). Antiestrogens induce transforming growth factor beta-mediated immunosuppression in breast cancer. Cancer Research, 70(4), 1314–1322. doi:10.1158/0008-5472.CAN-09-3292.
-
(2010)
Cancer Research
, vol.70
, Issue.4
, pp. 1314-1322
-
-
Joffroy, C.M.1
Buck, M.B.2
Stope, M.B.3
Popp, S.L.4
Pfizenmaier, K.5
Knabbe, C.6
-
60
-
-
84861175955
-
CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients
-
Rech, A. J., Mick, R., Martin, S., Recio, A., Aqui, N. A., Powell Jr., D. J., et al. (2012). CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients. Science Translational Medicine, 4(134), 134ra162. doi:10.1126/scitranslmed.3003330.
-
(2012)
Science Translational Medicine
, vol.4
, Issue.134
, pp. 134ra162
-
-
Rech, A.J.1
Mick, R.2
Martin, S.3
Recio, A.4
Aqui, N.A.5
Powell, D.J.6
-
61
-
-
84863154124
-
Trafficking of high avidity HER-2/neu-specific T cells into HER-2/neu-expressing tumors after depletion of effector/memory-like regulatory T cells
-
COI: 1:CAS:528:DC%2BC38XjtFWjtL8%3D, PID: 22359647
-
Weiss, V. L., Lee, T. H., Song, H., Kouo, T. S., Black, C. M., Sgouros, G., et al. (2012). Trafficking of high avidity HER-2/neu-specific T cells into HER-2/neu-expressing tumors after depletion of effector/memory-like regulatory T cells. PloS One, 7(2), e31962. doi:10.1371/journal.pone.0031962.
-
(2012)
PloS One
, vol.7
, Issue.2
-
-
Weiss, V.L.1
Lee, T.H.2
Song, H.3
Kouo, T.S.4
Black, C.M.5
Sgouros, G.6
-
62
-
-
84944454410
-
Depletion of regulatory T cells by targeting CC chemokine receptor type 4 with mogamulizumab
-
PID: 26140234
-
Ni, X., Langridge, T., & Duvic, M. (2015). Depletion of regulatory T cells by targeting CC chemokine receptor type 4 with mogamulizumab. Oncoimmunology, 4(7), e1011524. doi:10.1080/2162402X.2015.1011524.
-
(2015)
Oncoimmunology
, vol.4
, Issue.7
-
-
Ni, X.1
Langridge, T.2
Duvic, M.3
-
63
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
COI: 1:CAS:528:DC%2BD1MXhsFeqsbw%3D, PID: 19197294
-
Gabrilovich, D. I., & Nagaraj, S. (2009). Myeloid-derived suppressor cells as regulators of the immune system. Nature Reviews. Immunology, 9(3), 162–174. doi:10.1038/nri2506.
-
(2009)
Nature Reviews. Immunology
, vol.9
, Issue.3
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
64
-
-
84880264249
-
Myeloid-derived suppressor cells in breast cancer
-
COI: 1:CAS:528:DC%2BC3sXhtFajur3K, PID: 23828498
-
Markowitz, J., Wesolowski, R., Papenfuss, T., Brooks, T. R., & Carson 3rd, W. E. (2013). Myeloid-derived suppressor cells in breast cancer. Breast Cancer Research and Treatment, 140(1), 13–21. doi:10.1007/s10549-013-2618-7.
-
(2013)
Breast Cancer Research and Treatment
, vol.140
, Issue.1
, pp. 13-21
-
-
Markowitz, J.1
Wesolowski, R.2
Papenfuss, T.3
Brooks, T.R.4
Carson, W.E.5
-
65
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
COI: 1:CAS:528:DC%2BD1cXht1yqs7bN, PID: 18446337
-
Diaz-Montero, C. M., Salem, M. L., Nishimura, M. I., Garrett-Mayer, E., Cole, D. J., & Montero, A. J. (2009). Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunology, Immunotherapy, 58(1), 49–59. doi:10.1007/s00262-008-0523-4.
-
(2009)
Cancer Immunology, Immunotherapy
, vol.58
, Issue.1
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
Garrett-Mayer, E.4
Cole, D.J.5
Montero, A.J.6
-
66
-
-
11844277698
-
Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
-
COI: 1:CAS:528:DC%2BD2MXotFSg
-
Sinha, P., Clements, V. K., & Ostrand-Rosenberg, S. (2005). Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. Journal of Immunology, 174(2), 636–645.
-
(2005)
Journal of Immunology
, vol.174
, Issue.2
, pp. 636-645
-
-
Sinha, P.1
Clements, V.K.2
Ostrand-Rosenberg, S.3
-
67
-
-
63949088142
-
Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells
-
COI: 1:CAS:528:DC%2BD1MXjvFOitb4%3D, PID: 18979098
-
Morales, J. K., Kmieciak, M., Graham, L., Feldmesser, M., Bear, H. D., & Manjili, M. H. (2009). Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells. Cancer Immunology, Immunotherapy, 58(6), 941–953. doi:10.1007/s00262-008-0609-z.
-
(2009)
Cancer Immunology, Immunotherapy
, vol.58
, Issue.6
, pp. 941-953
-
-
Morales, J.K.1
Kmieciak, M.2
Graham, L.3
Feldmesser, M.4
Bear, H.D.5
Manjili, M.H.6
-
68
-
-
79954987520
-
The role of interleukin-12 on modulating myeloid-derived suppressor cells, increasing overall survival and reducing metastasis
-
COI: 1:CAS:528:DC%2BC3MXlvFyrt7Y%3D, PID: 21453419
-
Steding, C. E., Wu, S. T., Zhang, Y., Jeng, M. H., Elzey, B. D., & Kao, C. (2011). The role of interleukin-12 on modulating myeloid-derived suppressor cells, increasing overall survival and reducing metastasis. Immunology, 133(2), 221–238. doi:10.1111/j.1365-2567.2011.03429.x.
-
(2011)
Immunology
, vol.133
, Issue.2
, pp. 221-238
-
-
Steding, C.E.1
Wu, S.T.2
Zhang, Y.3
Jeng, M.H.4
Elzey, B.D.5
Kao, C.6
-
69
-
-
84862500053
-
A Th1 cytokine-enriched microenvironment enhances tumor killing by activated T cells armed with bispecific antibodies and inhibits the development of myeloid-derived suppressor cells
-
COI: 1:CAS:528:DC%2BC38XksFaku78%3D, PID: 21971587
-
Thakur, A., Schalk, D., Sarkar, S. H., Al-Khadimi, Z., Sarkar, F. H., & Lum, L. G. (2012). A Th1 cytokine-enriched microenvironment enhances tumor killing by activated T cells armed with bispecific antibodies and inhibits the development of myeloid-derived suppressor cells. Cancer Immunology, Immunotherapy, 61(4), 497–509. doi:10.1007/s00262-011-1116-1.
-
(2012)
Cancer Immunology, Immunotherapy
, vol.61
, Issue.4
, pp. 497-509
-
-
Thakur, A.1
Schalk, D.2
Sarkar, S.H.3
Al-Khadimi, Z.4
Sarkar, F.H.5
Lum, L.G.6
-
70
-
-
84857916510
-
Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer
-
COI: 1:CAS:528:DC%2BC38XitVSkuro%3D, PID: 22138748
-
Montero, A. J., Diaz-Montero, C. M., Deutsch, Y. E., Hurley, J., Koniaris, L. G., Rumboldt, T., et al. (2012). Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer. Breast Cancer Research and Treatment, 132(1), 215–223. doi:10.1007/s10549-011-1889-0.
-
(2012)
Breast Cancer Research and Treatment
, vol.132
, Issue.1
, pp. 215-223
-
-
Montero, A.J.1
Diaz-Montero, C.M.2
Deutsch, Y.E.3
Hurley, J.4
Koniaris, L.G.5
Rumboldt, T.6
-
71
-
-
81255138408
-
Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectives
-
COI: 1:CAS:528:DC%2BC3MXhsVKht7rO, PID: 22068654
-
Godin-Ethier, J., Hanafi, L. A., Piccirillo, C. A., & Lapointe, R. (2011). Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectives. Clinical Cancer Research, 17(22), 6985–6991. doi:10.1158/1078-0432.CCR-11-1331.
-
(2011)
Clinical Cancer Research
, vol.17
, Issue.22
, pp. 6985-6991
-
-
Godin-Ethier, J.1
Hanafi, L.A.2
Piccirillo, C.A.3
Lapointe, R.4
-
72
-
-
70350055199
-
Arginase: an emerging key player in the mammalian immune system
-
COI: 1:CAS:528:DC%2BD1MXhsVSks7rI, PID: 19764983
-
Munder, M. (2009). Arginase: an emerging key player in the mammalian immune system. British Journal of Pharmacology, 158(3), 638–651. doi:10.1111/j.1476-5381.2009.00291.x.
-
(2009)
British Journal of Pharmacology
, vol.158
, Issue.3
, pp. 638-651
-
-
Munder, M.1
-
73
-
-
84904999099
-
IDO is highly expressed in breast cancer and breast cancer-derived circulating microvesicles and associated to aggressive types of tumors by in silico analysis
-
COI: 1:CAS:528:DC%2BC2cXht1egurbF, PID: 24687552
-
Isla Larrain, M. T., Rabassa, M. E., Lacunza, E., Barbera, A., Creton, A., Segal-Eiras, A., et al. (2014). IDO is highly expressed in breast cancer and breast cancer-derived circulating microvesicles and associated to aggressive types of tumors by in silico analysis. Tumour Biology, 35(7), 6511–6519. doi:10.1007/s13277-014-1859-3.
-
(2014)
Tumour Biology
, vol.35
, Issue.7
, pp. 6511-6519
-
-
Isla Larrain, M.T.1
Rabassa, M.E.2
Lacunza, E.3
Barbera, A.4
Creton, A.5
Segal-Eiras, A.6
-
74
-
-
76249111086
-
IDO inhibits T-cell function through suppressing Vav1 expression and activation
-
COI: 1:CAS:528:DC%2BC3cXisFKrsrk%3D
-
Li, R., Wei, F., Yu, J., Li, H., Ren, X., & Hao, X. (2009). IDO inhibits T-cell function through suppressing Vav1 expression and activation. Cancer Biology & Therapy, 8(14), 1402–1408.
-
(2009)
Cancer Biology & Therapy
, vol.8
, Issue.14
, pp. 1402-1408
-
-
Li, R.1
Wei, F.2
Yu, J.3
Li, H.4
Ren, X.5
Hao, X.6
-
75
-
-
80052833629
-
Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells
-
COI: 1:CAS:528:DC%2BC3MXht1yqsLjE
-
Sun, J., Yu, J., Li, H., Yang, L., Wei, F., Yu, W., et al. (2011). Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells. Journal of Experimental & Clinical Cancer Research, 30, 82. doi:10.1186/1756-9966-30-82.
-
(2011)
Journal of Experimental & Clinical Cancer Research
, vol.30
, pp. 82
-
-
Sun, J.1
Yu, J.2
Li, H.3
Yang, L.4
Wei, F.5
Yu, W.6
-
76
-
-
34248173331
-
Indoleamine 2,3-dioxygenase and tumor-induced tolerance
-
COI: 1:CAS:528:DC%2BD2sXlt1Omtro%3D, PID: 17476344
-
Munn, D. H., & Mellor, A. L. (2007). Indoleamine 2,3-dioxygenase and tumor-induced tolerance. The Journal of Clinical Investigation, 117(5), 1147–1154. doi:10.1172/JCI31178.
-
(2007)
The Journal of Clinical Investigation
, vol.117
, Issue.5
, pp. 1147-1154
-
-
Munn, D.H.1
Mellor, A.L.2
-
77
-
-
84875462761
-
Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer
-
COI: 1:CAS:528:DC%2BC3sXksVynsr8%3D
-
Yu, J., Du, W., Yan, F., Wang, Y., Li, H., Cao, S., et al. (2013). Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer. Journal of Immunology, 190(7), 3783–3797. doi:10.4049/jimmunol.1201449.
-
(2013)
Journal of Immunology
, vol.190
, Issue.7
, pp. 3783-3797
-
-
Yu, J.1
Du, W.2
Yan, F.3
Wang, Y.4
Li, H.5
Cao, S.6
-
78
-
-
16244408626
-
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
-
COI: 1:CAS:528:DC%2BD2MXhvVSru7c%3D, PID: 15711557
-
Muller, A. J., DuHadaway, J. B., Donover, P. S., Sutanto-Ward, E., & Prendergast, G. C. (2005). Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nature Medicine, 11(3), 312–319. doi:10.1038/nm1196.
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 312-319
-
-
Muller, A.J.1
DuHadaway, J.B.2
Donover, P.S.3
Sutanto-Ward, E.4
Prendergast, G.C.5
-
79
-
-
84908005764
-
A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors
-
PID: 25327557
-
Soliman, H. H., Jackson, E., Neuger, T., Dees, E. C., Harvey, R. D., Han, H., et al. (2014). A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors. Oncotarget, 5(18), 8136–8146.
-
(2014)
Oncotarget
, vol.5
, Issue.18
, pp. 8136-8146
-
-
Soliman, H.H.1
Jackson, E.2
Neuger, T.3
Dees, E.C.4
Harvey, R.D.5
Han, H.6
-
80
-
-
85008413348
-
Abstract P2-11-09: A phase 2 randomized trial of the IDO pathway inhibitor indoximod in combination with taxane based chemotherapy for metastatic breast cancer: Preliminary data. Cancer Res, 76(4 Supplement)
-
Tang, S., Montero, A., Munn, D., Link, C., Vahanian, N., Kennedy, E., et al. (2016). Abstract P2-11-09: A phase 2 randomized trial of the IDO pathway inhibitor indoximod in combination with taxane based chemotherapy for metastatic breast cancer: Preliminary data. Cancer Res, 76(4 Supplement), P2-11-09-P12-11-09.
-
(2016)
P2-11-09-P12-11-09
-
-
Tang, S.1
Montero, A.2
Munn, D.3
Link, C.4
Vahanian, N.5
Kennedy, E.6
-
81
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
COI: 1:CAS:528:DC%2BC3cXlsVSgtLc%3D, PID: 20371344
-
Qian, B. Z., & Pollard, J. W. (2010). Macrophage diversity enhances tumor progression and metastasis. Cell, 141(1), 39–51. doi:10.1016/j.cell.2010.03.014.
-
(2010)
Cell
, vol.141
, Issue.1
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
82
-
-
82555181278
-
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions
-
PID: 22161841
-
Laoui, D., Movahedi, K., Van Overmeire, E., Van den Bossche, J., Schouppe, E., Mommer, C., et al. (2011). Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions. The International Journal of Developmental Biology, 55(7–9), 861–867. doi:10.1387/ijdb.113371dl.
-
(2011)
The International Journal of Developmental Biology
, vol.55
, Issue.7-9
, pp. 861-867
-
-
Laoui, D.1
Movahedi, K.2
Van Overmeire, E.3
Van den Bossche, J.4
Schouppe, E.5
Mommer, C.6
-
83
-
-
84879654727
-
The role of tumor-associated macrophages in breast cancer progression (review)
-
COI: 1:CAS:528:DC%2BC3sXhtFOltL%2FL, PID: 23673510
-
Obeid, E., Nanda, R., Fu, Y. X., & Olopade, O. I. (2013). The role of tumor-associated macrophages in breast cancer progression (review). International Journal of Oncology, 43(1), 5–12. doi:10.3892/ijo.2013.1938.
-
(2013)
International Journal of Oncology
, vol.43
, Issue.1
, pp. 5-12
-
-
Obeid, E.1
Nanda, R.2
Fu, Y.X.3
Olopade, O.I.4
-
84
-
-
84875253893
-
Tumor-associated macrophages as potential diagnostic and prognostic biomarkers in breast cancer
-
COI: 1:CAS:528:DC%2BC3sXit1ylurk%3D, PID: 23348699
-
Tang, X. (2013). Tumor-associated macrophages as potential diagnostic and prognostic biomarkers in breast cancer. Cancer Letters, 332(1), 3–10. doi:10.1016/j.canlet.2013.01.024.
-
(2013)
Cancer Letters
, vol.332
, Issue.1
, pp. 3-10
-
-
Tang, X.1
-
85
-
-
0029816609
-
Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
-
COI: 1:CAS:528:DyaK28XmsV2isbk%3D, PID: 8840975
-
Leek, R. D., Lewis, C. E., Whitehouse, R., Greenall, M., Clarke, J., & Harris, A. L. (1996). Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Research, 56(20), 4625–4629.
-
(1996)
Cancer Research
, vol.56
, Issue.20
, pp. 4625-4629
-
-
Leek, R.D.1
Lewis, C.E.2
Whitehouse, R.3
Greenall, M.4
Clarke, J.5
Harris, A.L.6
-
86
-
-
24744454660
-
Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density
-
COI: 1:CAS:528:DC%2BD2MXnslyqu70%3D, PID: 16012726
-
Tsutsui, S., Yasuda, K., Suzuki, K., Tahara, K., Higashi, H., & Era, S. (2005). Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density. Oncology Reports, 14(2), 425–431.
-
(2005)
Oncology Reports
, vol.14
, Issue.2
, pp. 425-431
-
-
Tsutsui, S.1
Yasuda, K.2
Suzuki, K.3
Tahara, K.4
Higashi, H.5
Era, S.6
-
87
-
-
84856104725
-
Tumour-infiltrating macrophages and clinical outcome in breast cancer
-
COI: 1:STN:280:DC%2BC387mtVynsA%3D%3D, PID: 22049225
-
Mahmoud, S. M., Lee, A. H., Paish, E. C., Macmillan, R. D., Ellis, I. O., & Green, A. R. (2012). Tumour-infiltrating macrophages and clinical outcome in breast cancer. Journal of Clinical Pathology, 65(2), 159–163. doi:10.1136/jclinpath-2011-200355.
-
(2012)
Journal of Clinical Pathology
, vol.65
, Issue.2
, pp. 159-163
-
-
Mahmoud, S.M.1
Lee, A.H.2
Paish, E.C.3
Macmillan, R.D.4
Ellis, I.O.5
Green, A.R.6
-
88
-
-
79960833961
-
Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome
-
PID: 20842526
-
Campbell, M. J., Tonlaar, N. Y., Garwood, E. R., Huo, D., Moore, D. H., Khramtsov, A. I., et al. (2011). Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome. Breast Cancer Research and Treatment, 128(3), 703–711. doi:10.1007/s10549-010-1154-y.
-
(2011)
Breast Cancer Research and Treatment
, vol.128
, Issue.3
, pp. 703-711
-
-
Campbell, M.J.1
Tonlaar, N.Y.2
Garwood, E.R.3
Huo, D.4
Moore, D.H.5
Khramtsov, A.I.6
-
89
-
-
47949096781
-
Cancer-related inflammation
-
COI: 1:CAS:528:DC%2BD1cXovV2mtbg%3D, PID: 18650914
-
Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008). Cancer-related inflammation. Nature, 454(7203), 436–444. doi:10.1038/nature07205.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
90
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
COI: 1:CAS:528:DC%2BC3cXhtFyhtrrL, PID: 20856220
-
Biswas, S. K., & Mantovani, A. (2010). Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nature Immunology, 11(10), 889–896. doi:10.1038/ni.1937.
-
(2010)
Nature Immunology
, vol.11
, Issue.10
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
91
-
-
84857692141
-
Differential macrophage programming in the tumor microenvironment
-
COI: 1:CAS:528:DC%2BC38Xjt1Orsbk%3D, PID: 22277903
-
Ruffell, B., Affara, N. I., & Coussens, L. M. (2012). Differential macrophage programming in the tumor microenvironment. Trends in Immunology, 33(3), 119–126. doi:10.1016/j.it.2011.12.001.
-
(2012)
Trends in Immunology
, vol.33
, Issue.3
, pp. 119-126
-
-
Ruffell, B.1
Affara, N.I.2
Coussens, L.M.3
-
92
-
-
84867902940
-
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
-
COI: 1:CAS:528:DC%2BC38XhvVSltLjK, PID: 23045683
-
Huang, Y., Yuan, J., Righi, E., Kamoun, W. S., Ancukiewicz, M., Nezivar, J., et al. (2012). Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proceedings of the National Academy of Sciences of the United States of America, 109(43), 17561–17566. doi:10.1073/pnas.1215397109.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, Issue.43
, pp. 17561-17566
-
-
Huang, Y.1
Yuan, J.2
Righi, E.3
Kamoun, W.S.4
Ancukiewicz, M.5
Nezivar, J.6
-
93
-
-
84879371298
-
Hydrazinocurcumin Encapsuled nanoparticles "re-educate" tumor-associated macrophages and exhibit anti-tumor effects on breast cancer following STAT3 suppression
-
COI: 1:CAS:528:DC%2BC3sXhtFWisbzL, PID: 23825527
-
Zhang, X., Tian, W., Cai, X., Wang, X., Dang, W., Tang, H., et al. (2013). Hydrazinocurcumin Encapsuled nanoparticles "re-educate" tumor-associated macrophages and exhibit anti-tumor effects on breast cancer following STAT3 suppression. PloS One, 8(6), e65896. doi:10.1371/journal.pone.0065896.
-
(2013)
PloS One
, vol.8
, Issue.6
-
-
Zhang, X.1
Tian, W.2
Cai, X.3
Wang, X.4
Dang, W.5
Tang, H.6
-
94
-
-
84866784798
-
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
-
COI: 1:CAS:528:DC%2BC3MXpsVylsbo%3D, PID: 22039576
-
DeNardo, D. G., Brennan, D. J., Rexhepaj, E., Ruffell, B., Shiao, S. L., Madden, S. F., et al. (2011). Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discovery, 1(1), 54–67. doi:10.1158/2159-8274.CD-10-0028.
-
(2011)
Cancer Discovery
, vol.1
, Issue.1
, pp. 54-67
-
-
DeNardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
Ruffell, B.4
Shiao, S.L.5
Madden, S.F.6
-
95
-
-
0034021278
-
Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
-
COI: 1:CAS:528:DC%2BD3cXisF2rtr0%3D, PID: 10699991
-
Leek, R. D., Hunt, N. C., Landers, R. J., Lewis, C. E., Royds, J. A., & Harris, A. L. (2000). Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. The Journal of Pathology, 190(4), 430–436. doi:10.1002/(SICI)1096-9896(200003)190:4<430::AID-PATH538>3.0.CO;2-6.
-
(2000)
The Journal of Pathology
, vol.190
, Issue.4
, pp. 430-436
-
-
Leek, R.D.1
Hunt, N.C.2
Landers, R.J.3
Lewis, C.E.4
Royds, J.A.5
Harris, A.L.6
-
96
-
-
0033780453
-
Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas
-
COI: 1:CAS:528:DC%2BD3cXnslert7k%3D, PID: 11004690
-
Lewis, J. S., Landers, R. J., Underwood, J. C., Harris, A. L., & Lewis, C. E. (2000). Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas. The Journal of Pathology, 192(2), 150–158. doi:10.1002/1096-9896(2000)9999:9999<::AID-PATH687>3.0.CO;2-G.
-
(2000)
The Journal of Pathology
, vol.192
, Issue.2
, pp. 150-158
-
-
Lewis, J.S.1
Landers, R.J.2
Underwood, J.C.3
Harris, A.L.4
Lewis, C.E.5
-
97
-
-
33845466231
-
Monocyte/macrophage infiltration in tumors: modulators of angiogenesis
-
COI: 1:CAS:528:DC%2BD28XhtlSisLjN, PID: 16997855
-
Dirkx, A. E., Oude Egbrink, M. G., Wagstaff, J., & Griffioen, A. W. (2006). Monocyte/macrophage infiltration in tumors: modulators of angiogenesis. Journal of Leukocyte Biology, 80(6), 1183–1196. doi:10.1189/jlb.0905495.
-
(2006)
Journal of Leukocyte Biology
, vol.80
, Issue.6
, pp. 1183-1196
-
-
Dirkx, A.E.1
Oude Egbrink, M.G.2
Wagstaff, J.3
Griffioen, A.W.4
-
98
-
-
45549103691
-
Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy
-
PID: 18539959
-
Kakarala, M., & Wicha, M. S. (2008). Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy. Journal of Clinical Oncology, 26(17), 2813–2820. doi:10.1200/JCO.2008.16.3931.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.17
, pp. 2813-2820
-
-
Kakarala, M.1
Wicha, M.S.2
-
99
-
-
80053401068
-
Breast cancer stem cells, cytokine networks, and the tumor microenvironment
-
COI: 1:CAS:528:DC%2BC3MXht12ht7vK, PID: 21965337
-
Korkaya, H., Liu, S., & Wicha, M. S. (2011). Breast cancer stem cells, cytokine networks, and the tumor microenvironment. The Journal of Clinical Investigation, 121(10), 3804–3809. doi:10.1172/JCI57099.
-
(2011)
The Journal of Clinical Investigation
, vol.121
, Issue.10
, pp. 3804-3809
-
-
Korkaya, H.1
Liu, S.2
Wicha, M.S.3
-
100
-
-
84874291853
-
Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway
-
COI: 1:CAS:528:DC%2BC3sXjvFOiu74%3D, PID: 23169551
-
Yang, J., Liao, D., Chen, C., Liu, Y., Chuang, T. H., Xiang, R., et al. (2013). Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway. Stem Cells, 31(2), 248–258. doi:10.1002/stem.1281.
-
(2013)
Stem Cells
, vol.31
, Issue.2
, pp. 248-258
-
-
Yang, J.1
Liao, D.2
Chen, C.3
Liu, Y.4
Chuang, T.H.5
Xiang, R.6
-
101
-
-
84864359517
-
Tumor associated macrophage x cancer cell hybrids may acquire cancer stem cell properties in breast cancer
-
COI: 1:CAS:528:DC%2BC38XhtFWlsbfE, PID: 22848668
-
Ding, J., Jin, W., Chen, C., Shao, Z., & Wu, J. (2012). Tumor associated macrophage x cancer cell hybrids may acquire cancer stem cell properties in breast cancer. PloS One, 7(7), e41942. doi:10.1371/journal.pone.0041942.
-
(2012)
PloS One
, vol.7
, Issue.7
-
-
Ding, J.1
Jin, W.2
Chen, C.3
Shao, Z.4
Wu, J.5
-
102
-
-
70350778443
-
An epigenetic switch involving NF-kappaB, Lin28, let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
COI: 1:CAS:528:DC%2BD1MXhsFylsbbM, PID: 19878981
-
Iliopoulos, D., Hirsch, H. A., & Struhl, K. (2009). An epigenetic switch involving NF-kappaB, Lin28, let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell, 139(4), 693–706. doi:10.1016/j.cell.2009.10.014.
-
(2009)
Cell
, vol.139
, Issue.4
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
103
-
-
0037455841
-
Circulating interleukin-6 predicts survival in patients with metastatic breast cancer
-
COI: 1:CAS:528:DC%2BD3sXmtFKnsw%3D%3D, PID: 12494472
-
Salgado, R., Junius, S., Benoy, I., Van Dam, P., Vermeulen, P., Van Marck, E., et al. (2003). Circulating interleukin-6 predicts survival in patients with metastatic breast cancer. International Journal of Cancer, 103(5), 642–646. doi:10.1002/ijc.10833.
-
(2003)
International Journal of Cancer
, vol.103
, Issue.5
, pp. 642-646
-
-
Salgado, R.1
Junius, S.2
Benoy, I.3
Van Dam, P.4
Vermeulen, P.5
Van Marck, E.6
-
104
-
-
84877826703
-
The role of intratumoral and systemic IL-6 in breast cancer
-
COI: 1:CAS:528:DC%2BC3sXmsFekurY%3D, PID: 23532539
-
Dethlefsen, C., Hojfeldt, G., & Hojman, P. (2013). The role of intratumoral and systemic IL-6 in breast cancer. Breast Cancer Research and Treatment, 138(3), 657–664. doi:10.1007/s10549-013-2488-z.
-
(2013)
Breast Cancer Research and Treatment
, vol.138
, Issue.3
, pp. 657-664
-
-
Dethlefsen, C.1
Hojfeldt, G.2
Hojman, P.3
-
105
-
-
84885659220
-
Interleukin-8 in breast cancer progression
-
COI: 1:CAS:528:DC%2BC3sXhsFOis7zO
-
Todorovic-Rakovic, N., & Milovanovic, J. (2013). Interleukin-8 in breast cancer progression. Journal of Interferon & Cytokine Research, 33(10), 563–570. doi:10.1089/jir.2013.0023.
-
(2013)
Journal of Interferon & Cytokine Research
, vol.33
, Issue.10
, pp. 563-570
-
-
Todorovic-Rakovic, N.1
Milovanovic, J.2
-
106
-
-
79959956046
-
The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(−) stem cell-like breast cancer cells in human tumors
-
COI: 1:CAS:528:DC%2BC3MXovVKgurc%3D, PID: 21633165
-
Marotta, L. L., Almendro, V., Marusyk, A., Shipitsin, M., Schemme, J., Walker, S. R., et al. (2011). The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(−) stem cell-like breast cancer cells in human tumors. The Journal of Clinical Investigation, 121(7), 2723–2735. doi:10.1172/JCI44745.
-
(2011)
The Journal of Clinical Investigation
, vol.121
, Issue.7
, pp. 2723-2735
-
-
Marotta, L.L.1
Almendro, V.2
Marusyk, A.3
Shipitsin, M.4
Schemme, J.5
Walker, S.R.6
-
107
-
-
60549111070
-
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
-
COI: 1:CAS:528:DC%2BD1MXhslynsrw%3D, PID: 19190339
-
Charafe-Jauffret, E., Ginestier, C., Iovino, F., Wicinski, J., Cervera, N., Finetti, P., et al. (2009). Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Research, 69(4), 1302–1313. doi:10.1158/0008-5472.CAN-08-2741.
-
(2009)
Cancer Research
, vol.69
, Issue.4
, pp. 1302-1313
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Iovino, F.3
Wicinski, J.4
Cervera, N.5
Finetti, P.6
-
108
-
-
84878552107
-
Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8
-
COI: 1:CAS:528:DC%2BC3sXosFSqt7Y%3D, PID: 23633491
-
Hartman, Z. C., Poage, G. M., den Hollander, P., Tsimelzon, A., Hill, J., Panupinthu, N., et al. (2013). Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8. Cancer Research, 73(11), 3470–3480. doi:10.1158/0008-5472.CAN-12-4524-T.
-
(2013)
Cancer Research
, vol.73
, Issue.11
, pp. 3470-3480
-
-
Hartman, Z.C.1
Poage, G.M.2
den Hollander, P.3
Tsimelzon, A.4
Hill, J.5
Panupinthu, N.6
-
109
-
-
84863349461
-
IL-6-induced epithelial-mesenchymal transition promotes the generation of breast cancer stem-like cells analogous to mammosphere cultures
-
COI: 1:CAS:528:DC%2BC38XlslKhsLk%3D, PID: 22134360
-
Xie, G., Yao, Q., Liu, Y., Du, S., Liu, A., Guo, Z., et al. (2012). IL-6-induced epithelial-mesenchymal transition promotes the generation of breast cancer stem-like cells analogous to mammosphere cultures. International Journal of Oncology, 40(4), 1171–1179. doi:10.3892/ijo.2011.1275.
-
(2012)
International Journal of Oncology
, vol.40
, Issue.4
, pp. 1171-1179
-
-
Xie, G.1
Yao, Q.2
Liu, Y.3
Du, S.4
Liu, A.5
Guo, Z.6
-
110
-
-
84878881786
-
-
Hwang, M. S., Yu, N., Stinson, S. Y., Yue, P., Newman, R. J., Allan, B. B., et al. (2013). miR-221/222 targets adiponectin receptor 1 to promote the epithelial-to-mesenchymal transition in breast cancer. PLoS One, 8(6), e66502, doi:10.1371/journal.pone.0066502
-
Hwang, M. S., Yu, N., Stinson, S. Y., Yue, P., Newman, R. J., Allan, B. B., et al. (2013). miR-221/222 targets adiponectin receptor 1 to promote the epithelial-to-mesenchymal transition in breast cancer. PLoS One, 8(6), e66502, doi:10.1371/journal.pone.0066502.
-
-
-
-
111
-
-
84870825008
-
JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer
-
COI: 1:CAS:528:DC%2BC38XhvVWgt7rM, PID: 23238015
-
Britschgi, A., Andraos, R., Brinkhaus, H., Klebba, I., Romanet, V., Muller, U., et al. (2012). JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer. Cancer Cell, 22(6), 796–811. doi:10.1016/j.ccr.2012.10.023.
-
(2012)
Cancer Cell
, vol.22
, Issue.6
, pp. 796-811
-
-
Britschgi, A.1
Andraos, R.2
Brinkhaus, H.3
Klebba, I.4
Romanet, V.5
Muller, U.6
-
112
-
-
84856223809
-
Dual HER2-targeted approaches in HER2-positive breast cancer
-
PID: 21956210
-
Ahn, E. R., & Vogel, C. L. (2012). Dual HER2-targeted approaches in HER2-positive breast cancer. Breast Cancer Research and Treatment, 131(2), 371–383. doi:10.1007/s10549-011-1781-y.
-
(2012)
Breast Cancer Research and Treatment
, vol.131
, Issue.2
, pp. 371-383
-
-
Ahn, E.R.1
Vogel, C.L.2
-
113
-
-
20544460650
-
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer
-
COI: 1:CAS:528:DC%2BD2MXlslWntr8%3D, PID: 15738535
-
Buzdar, A. U., Ibrahim, N. K., Francis, D., Booser, D. J., Thomas, E. S., Theriault, R. L., et al. (2005). Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer. Journal of Clinical Oncology, 23(16), 3676–3685. doi:10.1200/JCO.2005.07.032.
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.16
, pp. 3676-3685
-
-
Buzdar, A.U.1
Ibrahim, N.K.2
Francis, D.3
Booser, D.J.4
Thomas, E.S.5
Theriault, R.L.6
-
114
-
-
75149145066
-
Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort
-
COI: 1:CAS:528:DC%2BC3cXht12ltLk%3D, PID: 20113825
-
Gianni, L., Eiermann, W., Semiglazov, V., Manikhas, A., Lluch, A., Tjulandin, S., et al. (2010). Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort. Lancet, 375(9712), 377–384. doi:10.1016/S0140-6736(09)61964-4.
-
(2010)
Lancet
, vol.375
, Issue.9712
, pp. 377-384
-
-
Gianni, L.1
Eiermann, W.2
Semiglazov, V.3
Manikhas, A.4
Lluch, A.5
Tjulandin, S.6
-
115
-
-
79958296638
-
Trastuzumab in the adjuvant treatment of HER2-positive early breast cancer patients: a meta-analysis of published randomized controlled trials
-
COI: 1:CAS:528:DC%2BC3MXnslCmtrs%3D, PID: 21695277
-
Yin, W., Jiang, Y., Shen, Z., Shao, Z., & Lu, J. (2011). Trastuzumab in the adjuvant treatment of HER2-positive early breast cancer patients: a meta-analysis of published randomized controlled trials. PloS One, 6(6), e21030. doi:10.1371/journal.pone.0021030.
-
(2011)
PloS One
, vol.6
, Issue.6
-
-
Yin, W.1
Jiang, Y.2
Shen, Z.3
Shao, Z.4
Lu, J.5
-
116
-
-
79952041937
-
Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial
-
COI: 1:CAS:528:DC%2BC3MXjs1Cgur4%3D, PID: 21354370
-
Gianni, L., Dafni, U., Gelber, R. D., Azambuja, E., Muehlbauer, S., Goldhirsch, A., et al. (2011). Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial. The Lancet Oncology, 12(3), 236–244. doi:10.1016/S1470-2045(11)70033-X.
-
(2011)
The Lancet Oncology
, vol.12
, Issue.3
, pp. 236-244
-
-
Gianni, L.1
Dafni, U.2
Gelber, R.D.3
Azambuja, E.4
Muehlbauer, S.5
Goldhirsch, A.6
-
117
-
-
79960255931
-
Targeted therapy in breast cancer: what's new?
-
PID: 21706452
-
Fang, L., Barekati, Z., Zhang, B., Liu, Z., & Zhong, X. (2011). Targeted therapy in breast cancer: what's new? Swiss Medical Weekly, 141, w13231. doi:10.4414/smw.2011.13231.
-
(2011)
Swiss Medical Weekly
, vol.141
, pp. w13231
-
-
Fang, L.1
Barekati, Z.2
Zhang, B.3
Liu, Z.4
Zhong, X.5
-
118
-
-
84881325579
-
Novel targeted therapies to overcome trastuzumab resistance in HER2-overexpressing metastatic breast cancer
-
COI: 1:CAS:528:DC%2BC3sXht1WnsrbE, PID: 23531110
-
Huang, Y., Fu, P., & Fan, W. (2013). Novel targeted therapies to overcome trastuzumab resistance in HER2-overexpressing metastatic breast cancer. Current Drug Targets, 14(8), 889–898.
-
(2013)
Current Drug Targets
, vol.14
, Issue.8
, pp. 889-898
-
-
Huang, Y.1
Fu, P.2
Fan, W.3
-
119
-
-
1942474587
-
The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
-
COI: 1:CAS:528:DC%2BD2cXis1yjt7k%3D, PID: 15059883
-
Nahta, R., Hung, M. C., & Esteva, F. J. (2004). The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Research, 64(7), 2343–2346.
-
(2004)
Cancer Research
, vol.64
, Issue.7
, pp. 2343-2346
-
-
Nahta, R.1
Hung, M.C.2
Esteva, F.J.3
-
120
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
-
COI: 1:CAS:528:DC%2BD38XmslSksL4%3D, PID: 12204533
-
Agus, D. B., Akita, R. W., Fox, W. D., Lewis, G. D., Higgins, B., Pisacane, P. I., et al. (2002). Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell, 2(2), 127–137.
-
(2002)
Cancer Cell
, vol.2
, Issue.2
, pp. 127-137
-
-
Agus, D.B.1
Akita, R.W.2
Fox, W.D.3
Lewis, G.D.4
Higgins, B.5
Pisacane, P.I.6
-
121
-
-
1842605531
-
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
-
COI: 1:CAS:528:DC%2BD2cXjvVaqtLc%3D, PID: 15093539
-
Franklin, M. C., Carey, K. D., Vajdos, F. F., Leahy, D. J., de Vos, A. M., & Sliwkowski, M. X. (2004). Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. Cancer Cell, 5(4), 317–328.
-
(2004)
Cancer Cell
, vol.5
, Issue.4
, pp. 317-328
-
-
Franklin, M.C.1
Carey, K.D.2
Vajdos, F.F.3
Leahy, D.J.4
de Vos, A.M.5
Sliwkowski, M.X.6
-
122
-
-
73649149433
-
Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models
-
COI: 1:CAS:528:DC%2BD1MXhsFGrtbnM, PID: 19934333
-
Scheuer, W., Friess, T., Burtscher, H., Bossenmaier, B., Endl, J., & Hasmann, M. (2009). Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models. Cancer Research, 69(24), 9330–9336. doi:10.1158/0008-5472.CAN-08-4597.
-
(2009)
Cancer Research
, vol.69
, Issue.24
, pp. 9330-9336
-
-
Scheuer, W.1
Friess, T.2
Burtscher, H.3
Bossenmaier, B.4
Endl, J.5
Hasmann, M.6
-
123
-
-
84873804270
-
Pertuzumab: new hope for patients with HER2-positive breast cancer
-
COI: 1:STN:280:DC%2BC38bgtFChsw%3D%3D, PID: 22910839
-
Capelan, M., Pugliano, L., De Azambuja, E., Bozovic, I., Saini, K. S., Sotiriou, C., et al. (2013). Pertuzumab: new hope for patients with HER2-positive breast cancer. Annals of Oncology, 24(2), 273–282. doi:10.1093/annonc/mds328.
-
(2013)
Annals of Oncology
, vol.24
, Issue.2
, pp. 273-282
-
-
Capelan, M.1
Pugliano, L.2
De Azambuja, E.3
Bozovic, I.4
Saini, K.S.5
Sotiriou, C.6
-
124
-
-
84876970810
-
Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study
-
COI: 1:CAS:528:DC%2BC3sXmt1OksLg%3D, PID: 23602601
-
Swain, S. M., Kim, S. B., Cortes, J., Ro, J., Semiglazov, V., Campone, M., et al. (2013). Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study. The Lancet Oncology, 14(6), 461–471. doi:10.1016/S1470-2045(13)70130-X.
-
(2013)
The Lancet Oncology
, vol.14
, Issue.6
, pp. 461-471
-
-
Swain, S.M.1
Kim, S.B.2
Cortes, J.3
Ro, J.4
Semiglazov, V.5
Campone, M.6
-
125
-
-
84855297353
-
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
-
COI: 1:CAS:528:DC%2BC38XkslSmsQ%3D%3D, PID: 22153890
-
Gianni, L., Pienkowski, T., Im, Y. H., Roman, L., Tseng, L. M., Liu, M. C., et al. (2012). Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. The Lancet Oncology, 13(1), 25–32. doi:10.1016/S1470-2045(11)70336-9.
-
(2012)
The Lancet Oncology
, vol.13
, Issue.1
, pp. 25-32
-
-
Gianni, L.1
Pienkowski, T.2
Im, Y.H.3
Roman, L.4
Tseng, L.M.5
Liu, M.C.6
-
126
-
-
84858785688
-
Antibody therapy of cancer
-
COI: 1:CAS:528:DC%2BC38XksVegsbs%3D, PID: 22437872
-
Scott, A. M., Wolchok, J. D., & Old, L. J. (2012). Antibody therapy of cancer. Nature Reviews. Cancer, 12(4), 278–287. doi:10.1038/nrc3236.
-
(2012)
Nature Reviews. Cancer
, vol.12
, Issue.4
, pp. 278-287
-
-
Scott, A.M.1
Wolchok, J.D.2
Old, L.J.3
-
127
-
-
42949157368
-
Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
-
COI: 1:CAS:528:DC%2BD1cXmsFemsLg%3D, PID: 18347005
-
Musolino, A., Naldi, N., Bortesi, B., Pezzuolo, D., Capelletti, M., Missale, G., et al. (2008). Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. Journal of Clinical Oncology, 26(11), 1789–1796. doi:10.1200/JCO.2007.14.8957.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.11
, pp. 1789-1796
-
-
Musolino, A.1
Naldi, N.2
Bortesi, B.3
Pezzuolo, D.4
Capelletti, M.5
Missale, G.6
-
128
-
-
84871770952
-
A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer
-
COI: 1:CAS:528:DC%2BC3sXitlSmsr0%3D
-
Mellor, J. D., Brown, M. P., Irving, H. R., Zalcberg, J. R., & Dobrovic, A. (2013). A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer. Journal of Hematology & Oncology, 6, 1. doi:10.1186/1756-8722-6-1.
-
(2013)
Journal of Hematology & Oncology
, vol.6
, pp. 1
-
-
Mellor, J.D.1
Brown, M.P.2
Irving, H.R.3
Zalcberg, J.R.4
Dobrovic, A.5
-
129
-
-
84912138759
-
Bispecific antibody platforms for cancer immunotherapy
-
PID: 25195094
-
Lameris, R., de Bruin, R. C., Schneiders, F. L., van Bergen en Henegouwen, P. M., Verheul, H. M., de Gruijl, T. D., et al. (2014). Bispecific antibody platforms for cancer immunotherapy. Critical Reviews in Oncology/Hematology, 92(3), 153–165. doi:10.1016/j.critrevonc.2014.08.003.
-
(2014)
Critical Reviews in Oncology/Hematology
, vol.92
, Issue.3
, pp. 153-165
-
-
Lameris, R.1
de Bruin, R.C.2
Schneiders, F.L.3
van Bergen en Henegouwen, P.M.4
Verheul, H.M.5
de Gruijl, T.D.6
-
130
-
-
27144432842
-
Engineered antibody fragments and the rise of single domains
-
COI: 1:CAS:528:DC%2BD2MXpvVyrtrc%3D, PID: 16151406
-
Holliger, P., & Hudson, P. J. (2005). Engineered antibody fragments and the rise of single domains. Nature Biotechnology, 23(9), 1126–1136. doi:10.1038/nbt1142.
-
(2005)
Nature Biotechnology
, vol.23
, Issue.9
, pp. 1126-1136
-
-
Holliger, P.1
Hudson, P.J.2
-
131
-
-
62149129236
-
Therapeutic antibodies: successes, limitations and hopes for the future
-
COI: 1:CAS:528:DC%2BD1MXmsFWju7c%3D, PID: 19459844
-
Chames, P., Van Regenmortel, M., Weiss, E., & Baty, D. (2009). Therapeutic antibodies: successes, limitations and hopes for the future. British Journal of Pharmacology, 157(2), 220–233. doi:10.1111/j.1476-5381.2009.00190.x.
-
(2009)
British Journal of Pharmacology
, vol.157
, Issue.2
, pp. 220-233
-
-
Chames, P.1
Van Regenmortel, M.2
Weiss, E.3
Baty, D.4
-
132
-
-
84894078151
-
Inhibitory FcgammaRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity
-
COI: 1:CAS:528:DC%2BC2cXisVGqtLs%3D, PID: 24227819
-
Vaughan, A. T., Iriyama, C., Beers, S. A., Chan, C. H., Lim, S. H., Williams, E. L., et al. (2014). Inhibitory FcgammaRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity. Blood, 123(5), 669–677. doi:10.1182/blood-2013-04-490821.
-
(2014)
Blood
, vol.123
, Issue.5
, pp. 669-677
-
-
Vaughan, A.T.1
Iriyama, C.2
Beers, S.A.3
Chan, C.H.4
Lim, S.H.5
Williams, E.L.6
-
133
-
-
80054765331
-
A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies
-
COI: 1:CAS:528:DC%2BC3MXhtlKrtrbK, PID: 22014573
-
Schaefer, G., Haber, L., Crocker, L. M., Shia, S., Shao, L., Dowbenko, D., et al. (2011). A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. Cancer Cell, 20(4), 472–486. doi:10.1016/j.ccr.2011.09.003.
-
(2011)
Cancer Cell
, vol.20
, Issue.4
, pp. 472-486
-
-
Schaefer, G.1
Haber, L.2
Crocker, L.M.3
Shia, S.4
Shao, L.5
Dowbenko, D.6
-
134
-
-
62849095162
-
Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site
-
COI: 1:CAS:528:DC%2BD1MXjt1Cqurw%3D, PID: 19299620
-
Bostrom, J., Yu, S. F., Kan, D., Appleton, B. A., Lee, C. V., Billeci, K., et al. (2009). Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site. Science, 323(5921), 1610–1614. doi:10.1126/science.1165480.
-
(2009)
Science
, vol.323
, Issue.5921
, pp. 1610-1614
-
-
Bostrom, J.1
Yu, S.F.2
Kan, D.3
Appleton, B.A.4
Lee, C.V.5
Billeci, K.6
-
135
-
-
55249104916
-
Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro
-
COI: 1:CAS:528:DC%2BD1cXhtlSktb7F, PID: 18841159
-
Robinson, M. K., Hodge, K. M., Horak, E., Sundberg, A. L., Russeva, M., Shaller, C. C., et al. (2008). Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro. British Journal of Cancer, 99(9), 1415–1425. doi:10.1038/sj.bjc.6604700.
-
(2008)
British Journal of Cancer
, vol.99
, Issue.9
, pp. 1415-1425
-
-
Robinson, M.K.1
Hodge, K.M.2
Horak, E.3
Sundberg, A.L.4
Russeva, M.5
Shaller, C.C.6
-
136
-
-
84859409756
-
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3
-
COI: 1:CAS:528:DC%2BC38XjtlKjurY%3D, PID: 22248472
-
McDonagh, C. F., Huhalov, A., Harms, B. D., Adams, S., Paragas, V., Oyama, S., et al. (2012). Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3. Molecular Cancer Therapeutics, 11(3), 582–593. doi:10.1158/1535-7163.MCT-11-0820.
-
(2012)
Molecular Cancer Therapeutics
, vol.11
, Issue.3
, pp. 582-593
-
-
McDonagh, C.F.1
Huhalov, A.2
Harms, B.D.3
Adams, S.4
Paragas, V.5
Oyama, S.6
-
137
-
-
85008349727
-
MM-111, an ErbB2/ErbB3 bispecific antibody, effectively combines with lapatinib to inhibit growth of ErbB2-overexpressing tumor cells
-
Oyama, S. K., Paragas, V., Adams, S., Luus, L., Huhalov, A., Kudla, A. J., et al. (2011). MM-111, an ErbB2/ErbB3 bispecific antibody, effectively combines with lapatinib to inhibit growth of ErbB2-overexpressing tumor cells. Cancer Research, 71(8 Supplement), 654.
-
(2011)
Cancer Research
, vol.71
, pp. 654
-
-
Oyama, S.K.1
Paragas, V.2
Adams, S.3
Luus, L.4
Huhalov, A.5
Kudla, A.J.6
-
138
-
-
84866596013
-
Advances in bispecific biotherapeutics for the treatment of cancer
-
COI: 1:CAS:528:DC%2BC38XhtF2rtbvM, PID: 22858161
-
May, C., Sapra, P., & Gerber, H. P. (2012). Advances in bispecific biotherapeutics for the treatment of cancer. Biochemical Pharmacology, 84(9), 1105–1112. doi:10.1016/j.bcp.2012.07.011.
-
(2012)
Biochemical Pharmacology
, vol.84
, Issue.9
, pp. 1105-1112
-
-
May, C.1
Sapra, P.2
Gerber, H.P.3
-
139
-
-
77954676136
-
The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: results of a prospective randomized phase II/III trial
-
COI: 1:CAS:528:DC%2BC3cXhtFSisrbO, PID: 20473913
-
Heiss, M. M., Murawa, P., Koralewski, P., Kutarska, E., Kolesnik, O. O., Ivanchenko, V. V., et al. (2010). The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: results of a prospective randomized phase II/III trial. International Journal of Cancer, 127(9), 2209–2221. doi:10.1002/ijc.25423.
-
(2010)
International Journal of Cancer
, vol.127
, Issue.9
, pp. 2209-2221
-
-
Heiss, M.M.1
Murawa, P.2
Koralewski, P.3
Kutarska, E.4
Kolesnik, O.O.5
Ivanchenko, V.V.6
-
140
-
-
66249126868
-
The trifunctional antibody ertumaxomab destroys tumor cells that express low levels of human epidermal growth factor receptor 2
-
PID: 19435924
-
Jager, M., Schoberth, A., Ruf, P., Hess, J., & Lindhofer, H. (2009). The trifunctional antibody ertumaxomab destroys tumor cells that express low levels of human epidermal growth factor receptor 2. Cancer Research, 69(10), 4270–4276. doi:10.1158/0008-5472.CAN-08-2861.
-
(2009)
Cancer Research
, vol.69
, Issue.10
, pp. 4270-4276
-
-
Jager, M.1
Schoberth, A.2
Ruf, P.3
Hess, J.4
Lindhofer, H.5
-
141
-
-
84926099033
-
Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study
-
COI: 1:CAS:528:DC%2BC2MXht1yhsb0%3D, PID: 25524800
-
Topp, M. S., Gokbuget, N., Stein, A. S., Zugmaier, G., O'Brien, S., Bargou, R. C., et al. (2015). Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study. The Lancet Oncology, 16(1), 57–66. doi:10.1016/S1470-2045(14)71170-2.
-
(2015)
The Lancet Oncology
, vol.16
, Issue.1
, pp. 57-66
-
-
Topp, M.S.1
Gokbuget, N.2
Stein, A.S.3
Zugmaier, G.4
O'Brien, S.5
Bargou, R.C.6
-
142
-
-
84907494587
-
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells
-
COI: 1:CAS:528:DC%2BC2cXhs1Gntr7O, PID: 25228655
-
Junttila, T. T., Li, J., Johnston, J., Hristopoulos, M., Clark, R., Ellerman, D., et al. (2014). Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells. Cancer Research, 74(19), 5561–5571. doi:10.1158/0008-5472.CAN-13-3622-T.
-
(2014)
Cancer Research
, vol.74
, Issue.19
, pp. 5561-5571
-
-
Junttila, T.T.1
Li, J.2
Johnston, J.3
Hristopoulos, M.4
Clark, R.5
Ellerman, D.6
-
143
-
-
84655162706
-
Treatment of HER2-positive breast cancer: current status and future perspectives
-
COI: 1:CAS:528:DC%2BC3MXhs1CqtbbI
-
Arteaga, C. L., Sliwkowski, M. X., Osborne, C. K., Perez, E. A., Puglisi, F., & Gianni, L. (2012). Treatment of HER2-positive breast cancer: current status and future perspectives. Nature Reviews. Clinical Oncology, 9(1), 16–32. doi:10.1038/nrclinonc.2011.177.
-
(2012)
Nature Reviews. Clinical Oncology
, vol.9
, Issue.1
, pp. 16-32
-
-
Arteaga, C.L.1
Sliwkowski, M.X.2
Osborne, C.K.3
Perez, E.A.4
Puglisi, F.5
Gianni, L.6
-
144
-
-
84855406013
-
Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer
-
COI: 1:CAS:528:DC%2BC38XktFCmtg%3D%3D, PID: 22215104
-
Tsang, R. Y., & Finn, R. S. (2012). Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer. British Journal of Cancer, 106(1), 6–13. doi:10.1038/bjc.2011.516.
-
(2012)
British Journal of Cancer
, vol.106
, Issue.1
, pp. 6-13
-
-
Tsang, R.Y.1
Finn, R.S.2
-
145
-
-
84868520609
-
Trastuzumab emtansine for HER2-positive advanced breast cancer
-
COI: 1:CAS:528:DC%2BC38Xhs1ekt73M, PID: 23020162
-
Verma, S., Miles, D., Gianni, L., Krop, I. E., Welslau, M., Baselga, J., et al. (2012). Trastuzumab emtansine for HER2-positive advanced breast cancer. The New England Journal of Medicine, 367(19), 1783–1791. doi:10.1056/NEJMoa1209124.
-
(2012)
The New England Journal of Medicine
, vol.367
, Issue.19
, pp. 1783-1791
-
-
Verma, S.1
Miles, D.2
Gianni, L.3
Krop, I.E.4
Welslau, M.5
Baselga, J.6
-
146
-
-
77954031486
-
Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer
-
COI: 1:CAS:528:DC%2BC3cXoslykt7c%3D, PID: 20421541
-
Krop, I. E., Beeram, M., Modi, S., Jones, S. F., Holden, S. N., Yu, W., et al. (2010). Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer. Journal of Clinical Oncology, 28(16), 2698–2704. doi:10.1200/JCO.2009.26.2071.
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.16
, pp. 2698-2704
-
-
Krop, I.E.1
Beeram, M.2
Modi, S.3
Jones, S.F.4
Holden, S.N.5
Yu, W.6
-
147
-
-
84863688392
-
A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine
-
COI: 1:CAS:528:DC%2BC38XhsVKrsL%2FJ, PID: 22649126
-
Krop, I. E., LoRusso, P., Miller, K. D., Modi, S., Yardley, D., Rodriguez, G., et al. (2012). A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine. Journal of Clinical Oncology, 30(26), 3234–3241. doi:10.1200/JCO.2011.40.5902.
-
(2012)
Journal of Clinical Oncology
, vol.30
, Issue.26
, pp. 3234-3241
-
-
Krop, I.E.1
LoRusso, P.2
Miller, K.D.3
Modi, S.4
Yardley, D.5
Rodriguez, G.6
-
148
-
-
79952092706
-
Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy
-
COI: 1:CAS:528:DC%2BC3MXivFWmsrc%3D, PID: 21172893
-
Burris 3rd, H. A., Rugo, H. S., Vukelja, S. J., Vogel, C. L., Borson, R. A., Limentani, S., et al. (2011). Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy. Journal of Clinical Oncology, 29(4), 398–405. doi:10.1200/JCO.2010.29.5865.
-
(2011)
Journal of Clinical Oncology
, vol.29
, Issue.4
, pp. 398-405
-
-
Burris, H.A.1
Rugo, H.S.2
Vukelja, S.J.3
Vogel, C.L.4
Borson, R.A.5
Limentani, S.6
-
149
-
-
84875204170
-
Trastuzumab emtansine (T-DM1) for HER2-positive breast cancer
-
COI: 1:CAS:528:DC%2BC3sXktFOgtbs%3D, PID: 23402224
-
Boyraz, B., Sendur, M. A., Aksoy, S., Babacan, T., Roach, E. C., Kizilarslanoglu, M. C., et al. (2013). Trastuzumab emtansine (T-DM1) for HER2-positive breast cancer. Current Medical Research and Opinion, 29(4), 405–414. doi:10.1185/03007995.2013.775113.
-
(2013)
Current Medical Research and Opinion
, vol.29
, Issue.4
, pp. 405-414
-
-
Boyraz, B.1
Sendur, M.A.2
Aksoy, S.3
Babacan, T.4
Roach, E.C.5
Kizilarslanoglu, M.C.6
-
150
-
-
84901639476
-
Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial
-
COI: 1:CAS:528:DC%2BC2cXntl2gs7o%3D, PID: 24793816
-
Krop, I. E., Kim, S. B., Gonzalez-Martin, A., LoRusso, P. M., Ferrero, J. M., Smitt, M., et al. (2014). Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial. The Lancet Oncology, 15(7), 689–699. doi:10.1016/S1470-2045(14)70178-0.
-
(2014)
The Lancet Oncology
, vol.15
, Issue.7
, pp. 689-699
-
-
Krop, I.E.1
Kim, S.B.2
Gonzalez-Martin, A.3
LoRusso, P.M.4
Ferrero, J.M.5
Smitt, M.6
-
151
-
-
85008364795
-
-
Ellis, P. A., Barrios, C. H., Eiermann, W., Toi, M., Im, Y.-H., Conte, P. F., et al. Phase III, randomized study of trastuzumab emtansine (T-DM1){+/−} pertuzumab (P) vs trastuzumab+ taxane (HT) for first-line treatment of HER2-positive MBC: Primary results from the MARIANNE study. In ASCO Annual Meeting Proceedings, 2015 (Vol. 33, pp. 507, Vol. 15_suppl)
-
Ellis, P. A., Barrios, C. H., Eiermann, W., Toi, M., Im, Y.-H., Conte, P. F., et al. Phase III, randomized study of trastuzumab emtansine (T-DM1){+/−} pertuzumab (P) vs trastuzumab+ taxane (HT) for first-line treatment of HER2-positive MBC: Primary results from the MARIANNE study. In ASCO Annual Meeting Proceedings, 2015 (Vol. 33, pp. 507, Vol. 15_suppl)
-
-
-
-
152
-
-
85008343007
-
MM-302 shows clinical activity
-
LoRusso, P. (2015). MM-302 shows clinical activity, tolerability in heavily-pretreated HER2+ breast cancer http://www.onclive.com/conference-coverage/aacr-2015/MM-302-Shows-Clinical-Activity-Tolerability-in-Heavily-Pretreated-HER2-Breast-Cancer#sthash.4vGDpDX1.dpuf.
-
(2015)
tolerability in heavily-pretreated HER2+ breast cancer
-
-
LoRusso, P.1
-
153
-
-
84872473737
-
Vaccination for the prevention and treatment of breast cancer with special focus on Her-2/neu peptide vaccines
-
COI: 1:CAS:528:DC%2BC3sXjsFOhtLo%3D, PID: 23340862
-
Wiedermann, U., Davis, A. B., & Zielinski, C. C. (2013). Vaccination for the prevention and treatment of breast cancer with special focus on Her-2/neu peptide vaccines. Breast Cancer Research and Treatment, 138(1), 1–12. doi:10.1007/s10549-013-2410-8.
-
(2013)
Breast Cancer Research and Treatment
, vol.138
, Issue.1
, pp. 1-12
-
-
Wiedermann, U.1
Davis, A.B.2
Zielinski, C.C.3
-
154
-
-
0020594551
-
Multiple tumour-specific antigens expressed on a single tumour cell
-
COI: 1:STN:280:DyaL3s3ksFShsA%3D%3D, PID: 6602947
-
Wortzel, R. D., Philipps, C., & Schreiber, H. (1983). Multiple tumour-specific antigens expressed on a single tumour cell. Nature, 304(5922), 165–167.
-
(1983)
Nature
, vol.304
, Issue.5922
, pp. 165-167
-
-
Wortzel, R.D.1
Philipps, C.2
Schreiber, H.3
-
155
-
-
32944457941
-
Tumor antigen expression in melanoma varies according to antigen and stage
-
COI: 1:CAS:528:DC%2BD28XhtFeitbc%3D, PID: 16467087
-
Barrow, C., Browning, J., MacGregor, D., Davis, I. D., Sturrock, S., Jungbluth, A. A., et al. (2006). Tumor antigen expression in melanoma varies according to antigen and stage. Clinical Cancer Research, 12(3 Pt 1), 764–771. doi:10.1158/1078-0432.CCR-05-1544.
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.3
, pp. 764-771
-
-
Barrow, C.1
Browning, J.2
MacGregor, D.3
Davis, I.D.4
Sturrock, S.5
Jungbluth, A.A.6
-
156
-
-
54049092448
-
Optimal dose and schedule of an HER-2/neu (E75) peptide vaccine to prevent breast cancer recurrence: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
COI: 1:CAS:528:DC%2BD1cXht1Ggu7bK, PID: 18726994
-
Holmes, J. P., Gates, J. D., Benavides, L. C., Hueman, M. T., Carmichael, M. G., Patil, R., et al. (2008). Optimal dose and schedule of an HER-2/neu (E75) peptide vaccine to prevent breast cancer recurrence: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer, 113(7), 1666–1675. doi:10.1002/cncr.23772.
-
(2008)
Cancer
, vol.113
, Issue.7
, pp. 1666-1675
-
-
Holmes, J.P.1
Gates, J.D.2
Benavides, L.C.3
Hueman, M.T.4
Carmichael, M.G.5
Patil, R.6
-
157
-
-
38949139497
-
Combined clinical trial results of a HER2/neu (E75) vaccine for the prevention of recurrence in high-risk breast cancer patients: U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
COI: 1:CAS:528:DC%2BD1cXhsFykt7o%3D, PID: 18245541
-
Peoples, G. E., Holmes, J. P., Hueman, M. T., Mittendorf, E. A., Amin, A., Khoo, S., et al. (2008). Combined clinical trial results of a HER2/neu (E75) vaccine for the prevention of recurrence in high-risk breast cancer patients: U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Clinical Cancer Research, 14(3), 797–803. doi:10.1158/1078-0432.CCR-07-1448.
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.3
, pp. 797-803
-
-
Peoples, G.E.1
Holmes, J.P.2
Hueman, M.T.3
Mittendorf, E.A.4
Amin, A.5
Khoo, S.6
-
158
-
-
77956070565
-
Anti-HER2 vaccines: new prospects for breast cancer therapy
-
COI: 1:CAS:528:DC%2BC3cXotVOlurk%3D, PID: 20532501
-
Ladjemi, M. Z., Jacot, W., Chardes, T., Pelegrin, A., & Navarro-Teulon, I. (2010). Anti-HER2 vaccines: new prospects for breast cancer therapy. Cancer Immunology, Immunotherapy, 59(9), 1295–1312. doi:10.1007/s00262-010-0869-2.
-
(2010)
Cancer Immunology, Immunotherapy
, vol.59
, Issue.9
, pp. 1295-1312
-
-
Ladjemi, M.Z.1
Jacot, W.2
Chardes, T.3
Pelegrin, A.4
Navarro-Teulon, I.5
-
159
-
-
33745914659
-
Levels of circulating regulatory CD4+CD25+ T cells are decreased in breast cancer patients after vaccination with a HER2/neu peptide (E75) and GM-CSF vaccine
-
COI: 1:CAS:528:DC%2BD28XmvVaqsbY%3D, PID: 16758122
-
Hueman, M. T., Stojadinovic, A., Storrer, C. E., Foley, R. J., Gurney, J. M., Shriver, C. D., et al. (2006). Levels of circulating regulatory CD4+CD25+ T cells are decreased in breast cancer patients after vaccination with a HER2/neu peptide (E75) and GM-CSF vaccine. Breast Cancer Research and Treatment, 98(1), 17–29. doi:10.1007/s10549-005-9108-5.
-
(2006)
Breast Cancer Research and Treatment
, vol.98
, Issue.1
, pp. 17-29
-
-
Hueman, M.T.1
Stojadinovic, A.2
Storrer, C.E.3
Foley, R.J.4
Gurney, J.M.5
Shriver, C.D.6
-
160
-
-
33751503550
-
Analysis of naive and memory CD4 and CD8 T cell populations in breast cancer patients receiving a HER2/neu peptide (E75) and GM-CSF vaccine
-
COI: 1:CAS:528:DC%2BD28Xht1Gnu7vF, PID: 16783576
-
Hueman, M. T., Stojadinovic, A., Storrer, C. E., Dehqanzada, Z. A., Gurney, J. M., Shriver, C. D., et al. (2007). Analysis of naive and memory CD4 and CD8 T cell populations in breast cancer patients receiving a HER2/neu peptide (E75) and GM-CSF vaccine. Cancer Immunology, Immunotherapy, 56(2), 135–146. doi:10.1007/s00262-006-0188-9.
-
(2007)
Cancer Immunology, Immunotherapy
, vol.56
, Issue.2
, pp. 135-146
-
-
Hueman, M.T.1
Stojadinovic, A.2
Storrer, C.E.3
Dehqanzada, Z.A.4
Gurney, J.M.5
Shriver, C.D.6
-
161
-
-
79251503953
-
Use of booster inoculations to sustain the clinical effect of an adjuvant breast cancer vaccine: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
COI: 1:CAS:528:DC%2BC3MXitFKit7k%3D, PID: 20845479
-
Holmes, J. P., Clifton, G. T., Patil, R., Benavides, L. C., Gates, J. D., Stojadinovic, A., et al. (2011). Use of booster inoculations to sustain the clinical effect of an adjuvant breast cancer vaccine: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer, 117(3), 463–471. doi:10.1002/cncr.25586.
-
(2011)
Cancer
, vol.117
, Issue.3
, pp. 463-471
-
-
Holmes, J.P.1
Clifton, G.T.2
Patil, R.3
Benavides, L.C.4
Gates, J.D.5
Stojadinovic, A.6
-
162
-
-
84860700518
-
Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
COI: 1:CAS:528:DC%2BC38XmsVWnur0%3D, PID: 21989902
-
Mittendorf, E. A., Clifton, G. T., Holmes, J. P., Clive, K. S., Patil, R., Benavides, L. C., et al. (2012). Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer, 118(10), 2594–2602. doi:10.1002/cncr.26574.
-
(2012)
Cancer
, vol.118
, Issue.10
, pp. 2594-2602
-
-
Mittendorf, E.A.1
Clifton, G.T.2
Holmes, J.P.3
Clive, K.S.4
Patil, R.5
Benavides, L.C.6
-
163
-
-
85008332339
-
Abstract P5-16-02: Final results of the phase I/II trials of the E75 adjuvant breast cancer vaccine. Cancer Res, 72(24 Supplement)
-
Vreeland, T. J., Clifton, G. T., Hale, D. F., Sears, A., Patil, R., Holmes, J., et al. (2012). Abstract P5-16-02: Final results of the phase I/II trials of the E75 adjuvant breast cancer vaccine. Cancer Res, 72(24 Supplement), P5-16-02-P15-16-02.
-
(2012)
P5-16-02-P15-16-02
-
-
Vreeland, T.J.1
Clifton, G.T.2
Hale, D.F.3
Sears, A.4
Patil, R.5
Holmes, J.6
-
164
-
-
84906847366
-
Final report of the phase I/II clinical trial of the E75 (nelipepimut-S) vaccine with booster inoculations to prevent disease recurrence in high-risk breast cancer patients
-
COI: 1:STN:280:DC%2BC2cfgtFyhuw%3D%3D, PID: 24907636
-
Mittendorf, E. A., Clifton, G. T., Holmes, J. P., Schneble, E., van Echo, D., Ponniah, S., et al. (2014). Final report of the phase I/II clinical trial of the E75 (nelipepimut-S) vaccine with booster inoculations to prevent disease recurrence in high-risk breast cancer patients. Annals of Oncology, 25(9), 1735–1742. doi:10.1093/annonc/mdu211.
-
(2014)
Annals of Oncology
, vol.25
, Issue.9
, pp. 1735-1742
-
-
Mittendorf, E.A.1
Clifton, G.T.2
Holmes, J.P.3
Schneble, E.4
van Echo, D.5
Ponniah, S.6
-
165
-
-
75649136936
-
Results of the first phase 1 clinical trial of the HER-2/neu peptide (GP2) vaccine in disease-free breast cancer patients: United States Military Cancer Institute Clinical Trials Group Study I-04
-
COI: 1:CAS:528:DC%2BC3cXitFGit78%3D, PID: 19924797
-
Carmichael, M. G., Benavides, L. C., Holmes, J. P., Gates, J. D., Mittendorf, E. A., Ponniah, S., et al. (2010). Results of the first phase 1 clinical trial of the HER-2/neu peptide (GP2) vaccine in disease-free breast cancer patients: United States Military Cancer Institute Clinical Trials Group Study I-04. Cancer, 116(2), 292–301. doi:10.1002/cncr.24756.
-
(2010)
Cancer
, vol.116
, Issue.2
, pp. 292-301
-
-
Carmichael, M.G.1
Benavides, L.C.2
Holmes, J.P.3
Gates, J.D.4
Mittendorf, E.A.5
Ponniah, S.6
-
166
-
-
85008343024
-
-
Trappey, F., Berry, J. S., Vreeland, T. J., Hale, D. F., Sears, A. K., Ponniah, S., et al. 2013 Randomized phase II clinical trial of the anti-HER2 (GP2) vaccine to prevent recurrence in high-risk breast cancer patients: a planned interim analysis. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
Trappey, F., Berry, J. S., Vreeland, T. J., Hale, D. F., Sears, A. K., Ponniah, S., et al. 2013 Randomized phase II clinical trial of the anti-HER2 (GP2) vaccine to prevent recurrence in high-risk breast cancer patients: a planned interim analysis. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
-
-
-
167
-
-
84859018209
-
The GP2 peptide: a HER2/neu-based breast cancer vaccine
-
COI: 1:CAS:528:DC%2BC38Xkt1Oltb4%3D, PID: 22441896
-
Clive, K. S., Tyler, J. A., Clifton, G. T., Holmes, J. P., Ponniah, S., Peoples, G. E., et al. (2012). The GP2 peptide: a HER2/neu-based breast cancer vaccine. Journal of Surgical Oncology, 105(5), 452–458. doi:10.1002/jso.21723.
-
(2012)
Journal of Surgical Oncology
, vol.105
, Issue.5
, pp. 452-458
-
-
Clive, K.S.1
Tyler, J.A.2
Clifton, G.T.3
Holmes, J.P.4
Ponniah, S.5
Peoples, G.E.6
-
168
-
-
33847405324
-
Ii-Key/HER-2/neu(776-790) hybrid peptides induce more effective immunological responses over the native peptide in lymphocyte cultures from patients with HER-2/neu+ tumors
-
COI: 1:CAS:528:DC%2BD2sXisVaqtbs%3D, PID: 16960693
-
Sotiriadou, N. N., Kallinteris, N. L., Gritzapis, A. D., Voutsas, I. F., Papamichail, M., von Hofe, E., et al. (2007). Ii-Key/HER-2/neu(776-790) hybrid peptides induce more effective immunological responses over the native peptide in lymphocyte cultures from patients with HER-2/neu+ tumors. Cancer Immunology, Immunotherapy, 56(5), 601–613. doi:10.1007/s00262-006-0213-z.
-
(2007)
Cancer Immunology, Immunotherapy
, vol.56
, Issue.5
, pp. 601-613
-
-
Sotiriadou, N.N.1
Kallinteris, N.L.2
Gritzapis, A.D.3
Voutsas, I.F.4
Papamichail, M.5
von Hofe, E.6
-
169
-
-
49149117772
-
Results of the first phase I clinical trial of the novel II-key hybrid preventive HER-2/neu peptide (AE37) vaccine
-
COI: 1:CAS:528:DC%2BD1cXpvVWitrk%3D, PID: 18612158
-
Holmes, J. P., Benavides, L. C., Gates, J. D., Carmichael, M. G., Hueman, M. T., Mittendorf, E. A., et al. (2008). Results of the first phase I clinical trial of the novel II-key hybrid preventive HER-2/neu peptide (AE37) vaccine. Journal of Clinical Oncology, 26(20), 3426–3433. doi:10.1200/JCO.2007.15.7842.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.20
, pp. 3426-3433
-
-
Holmes, J.P.1
Benavides, L.C.2
Gates, J.D.3
Carmichael, M.G.4
Hueman, M.T.5
Mittendorf, E.A.6
-
170
-
-
77958196145
-
Circulating regulatory T cells (CD4+CD25+FOXP3+) decrease in breast cancer patients after vaccination with a modified MHC class II HER2/neu (AE37) peptide
-
COI: 1:CAS:528:DC%2BC3cXhtlenu7zN, PID: 20858449
-
Gates, J. D., Clifton, G. T., Benavides, L. C., Sears, A. K., Carmichael, M. G., Hueman, M. T., et al. (2010). Circulating regulatory T cells (CD4+CD25+FOXP3+) decrease in breast cancer patients after vaccination with a modified MHC class II HER2/neu (AE37) peptide. Vaccine, 28(47), 7476–7482. doi:10.1016/j.vaccine.2010.09.029.
-
(2010)
Vaccine
, vol.28
, Issue.47
, pp. 7476-7482
-
-
Gates, J.D.1
Clifton, G.T.2
Benavides, L.C.3
Sears, A.K.4
Carmichael, M.G.5
Hueman, M.T.6
-
171
-
-
80053643169
-
AE37: a novel T-cell-eliciting vaccine for breast cancer
-
COI: 1:CAS:528:DC%2BC3MXht1ylsrnK, PID: 21895539
-
Sears, A. K., Perez, S. A., Clifton, G. T., Benavides, L. C., Gates, J. D., Clive, K. S., et al. (2011). AE37: a novel T-cell-eliciting vaccine for breast cancer. Expert Opinion on Biological Therapy, 11(11), 1543–1550. doi:10.1517/14712598.2011.616889.
-
(2011)
Expert Opinion on Biological Therapy
, vol.11
, Issue.11
, pp. 1543-1550
-
-
Sears, A.K.1
Perez, S.A.2
Clifton, G.T.3
Benavides, L.C.4
Gates, J.D.5
Clive, K.S.6
-
172
-
-
85008382705
-
P1-13-01: an update of a phase II trial of the HER2 peptide AE37 vaccine in breast cancer patients to prevent recurrence
-
Hale, D., Perez, S., Sears, A., Clifton, G., Vreeland, T., Holmes, J., et al. (2011). P1-13-01: an update of a phase II trial of the HER2 peptide AE37 vaccine in breast cancer patients to prevent recurrence. Cancer Research, 71(24 Supplement), P1-13-01-P11-13-01.
-
(2011)
Cancer Research
, vol.71
-
-
Hale, D.1
Perez, S.2
Sears, A.3
Clifton, G.4
Vreeland, T.5
Holmes, J.6
-
173
-
-
84923105968
-
Primary analysis of the prospective, randomized, single-blinded phase II trial of AE37 vaccine versus GM-CSF alone administered in the adjuvant setting to high-risk breast cancer patients
-
Mittendorf, E. A., Schneble, E. J., Perez, S. A., Symanowski, R. P., Vreeland, T. J., Berry, J. S., et al. (2014). Primary analysis of the prospective, randomized, single-blinded phase II trial of AE37 vaccine versus GM-CSF alone administered in the adjuvant setting to high-risk breast cancer patients. Journal of Clinical Oncology, 32, 5s.
-
(2014)
Journal of Clinical Oncology
, vol.32
, pp. 5s
-
-
Mittendorf, E.A.1
Schneble, E.J.2
Perez, S.A.3
Symanowski, R.P.4
Vreeland, T.J.5
Berry, J.S.6
-
174
-
-
84902687147
-
Vaccine-specific T-cell proliferation in response to a dual peptide cancer vaccine in breast and ovarian cancer patients
-
Schneble, E. J., Berry, J. S., Trappey, A. F., Vreeland, T. J., Hale, D. F., Sears, A. K., et al. (2013). Vaccine-specific T-cell proliferation in response to a dual peptide cancer vaccine in breast and ovarian cancer patients. Journal for immunotherapy of cancer, 1(1), 1–1.
-
(2013)
Journal for immunotherapy of cancer
, vol.1
, Issue.1
, pp. 1
-
-
Schneble, E.J.1
Berry, J.S.2
Trappey, A.F.3
Vreeland, T.J.4
Hale, D.F.5
Sears, A.K.6
-
175
-
-
80054766687
-
Antitumor effect of new HER2 peptide vaccination based on B cell epitope
-
COI: 1:CAS:528:DC%2BC3MXhtl2rs7fF, PID: 21965747
-
Miyako, H., Kametani, Y., Katano, I., Ito, R., Tsuda, B., Furukawa, A., et al. (2011). Antitumor effect of new HER2 peptide vaccination based on B cell epitope. Anticancer Research, 31(10), 3361–3368.
-
(2011)
Anticancer Research
, vol.31
, Issue.10
, pp. 3361-3368
-
-
Miyako, H.1
Kametani, Y.2
Katano, I.3
Ito, R.4
Tsuda, B.5
Furukawa, A.6
-
176
-
-
0034660850
-
Prevention of mammary tumors with a chimeric HER-2 B-cell epitope peptide vaccine
-
COI: 1:CAS:528:DC%2BD3cXlt1Gkt7w%3D, PID: 10919651
-
Dakappagari, N. K., Douglas, D. B., Triozzi, P. L., Stevens, V. C., & Kaumaya, P. T. (2000). Prevention of mammary tumors with a chimeric HER-2 B-cell epitope peptide vaccine. Cancer Research, 60(14), 3782–3789.
-
(2000)
Cancer Research
, vol.60
, Issue.14
, pp. 3782-3789
-
-
Dakappagari, N.K.1
Douglas, D.B.2
Triozzi, P.L.3
Stevens, V.C.4
Kaumaya, P.T.5
-
177
-
-
0037446525
-
A chimeric multi-human epidermal growth factor receptor-2 B cell epitope peptide vaccine mediates superior antitumor responses
-
COI: 1:CAS:528:DC%2BD3sXislers7s%3D
-
Dakappagari, N. K., Pyles, J., Parihar, R., Carson, W. E., Young, D. C., & Kaumaya, P. T. (2003). A chimeric multi-human epidermal growth factor receptor-2 B cell epitope peptide vaccine mediates superior antitumor responses. Journal of Immunology, 170(8), 4242–4253.
-
(2003)
Journal of Immunology
, vol.170
, Issue.8
, pp. 4242-4253
-
-
Dakappagari, N.K.1
Pyles, J.2
Parihar, R.3
Carson, W.E.4
Young, D.C.5
Kaumaya, P.T.6
-
178
-
-
70449727895
-
Phase I active immunotherapy with combination of two chimeric, human epidermal growth factor receptor 2, B-cell epitopes fused to a promiscuous T-cell epitope in patients with metastatic and/or recurrent solid tumors
-
COI: 1:CAS:528:DC%2BD1MXhsFahsLnN, PID: 19752336
-
Kaumaya, P. T., Foy, K. C., Garrett, J., Rawale, S. V., Vicari, D., Thurmond, J. M., et al. (2009). Phase I active immunotherapy with combination of two chimeric, human epidermal growth factor receptor 2, B-cell epitopes fused to a promiscuous T-cell epitope in patients with metastatic and/or recurrent solid tumors. Journal of Clinical Oncology, 27(31), 5270–5277. doi:10.1200/JCO.2009.22.3883.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.31
, pp. 5270-5277
-
-
Kaumaya, P.T.1
Foy, K.C.2
Garrett, J.3
Rawale, S.V.4
Vicari, D.5
Thurmond, J.M.6
-
179
-
-
74849113525
-
A virosomal formulated Her-2/neu multi-peptide vaccine induces Her-2/neu-specific immune responses in patients with metastatic breast cancer: a phase I study
-
COI: 1:CAS:528:DC%2BC3cXlslWruw%3D%3D, PID: 20092022
-
Wiedermann, U., Wiltschke, C., Jasinska, J., Kundi, M., Zurbriggen, R., Garner-Spitzer, E., et al. (2010). A virosomal formulated Her-2/neu multi-peptide vaccine induces Her-2/neu-specific immune responses in patients with metastatic breast cancer: a phase I study. Breast Cancer Research and Treatment, 119(3), 673–683.
-
(2010)
Breast Cancer Research and Treatment
, vol.119
, Issue.3
, pp. 673-683
-
-
Wiedermann, U.1
Wiltschke, C.2
Jasinska, J.3
Kundi, M.4
Zurbriggen, R.5
Garner-Spitzer, E.6
-
180
-
-
84860188105
-
Therapeutic cancer vaccines: current status and moving forward
-
COI: 1:CAS:528:DC%2BC38Xmt1Shur8%3D, PID: 22395641
-
Schlom, J. (2012). Therapeutic cancer vaccines: current status and moving forward. Journal of the National Cancer Institute, 104(8), 599–613. doi:10.1093/jnci/djs033.
-
(2012)
Journal of the National Cancer Institute
, vol.104
, Issue.8
, pp. 599-613
-
-
Schlom, J.1
-
181
-
-
65349097929
-
The impact of HER2/neu expression level on response to the E75 vaccine: from U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
COI: 1:CAS:528:DC%2BD1MXksV2nt70%3D, PID: 19351776
-
Benavides, L. C., Gates, J. D., Carmichael, M. G., Patil, R., Holmes, J. P., Hueman, M. T., et al. (2009). The impact of HER2/neu expression level on response to the E75 vaccine: from U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Clinical Cancer Research, 15(8), 2895–2904. doi:10.1158/1078-0432.CCR-08-1126.
-
(2009)
Clinical Cancer Research
, vol.15
, Issue.8
, pp. 2895-2904
-
-
Benavides, L.C.1
Gates, J.D.2
Carmichael, M.G.3
Patil, R.4
Holmes, J.P.5
Hueman, M.T.6
-
182
-
-
70350435441
-
Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer
-
COI: 1:CAS:528:DC%2BD1MXhtlGgtbnK, PID: 19720923
-
Disis, M. L., Wallace, D. R., Gooley, T. A., Dang, Y., Slota, M., Lu, H., et al. (2009). Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer. Journal of Clinical Oncology, 27(28), 4685–4692. doi:10.1200/JCO.2008.20.6789.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.28
, pp. 4685-4692
-
-
Disis, M.L.1
Wallace, D.R.2
Gooley, T.A.3
Dang, Y.4
Slota, M.5
Lu, H.6
-
183
-
-
85008340772
-
-
Patil, R., Clifton, G. T., Litton, J. K., Shumway, N. M., Vreeland, T. J., Berry, J. S., et al. 2013 Safety and efficacy of the HER2-derived GP2 peptide vaccine in combination with trastuzumab for breast cancer patients in the adjuvant setting. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
Patil, R., Clifton, G. T., Litton, J. K., Shumway, N. M., Vreeland, T. J., Berry, J. S., et al. 2013 Safety and efficacy of the HER2-derived GP2 peptide vaccine in combination with trastuzumab for breast cancer patients in the adjuvant setting. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
-
-
-
184
-
-
80052420081
-
Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus
-
COI: 1:CAS:528:DC%2BC3MXnsVajtL4%3D, PID: 21673660
-
Cerullo, V., Diaconu, I., Kangasniemi, L., Rajecki, M., Escutenaire, S., Koski, A., et al. (2011). Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus. Molecular Therapy, 19(9), 1737–1746. doi:10.1038/mt.2011.113.
-
(2011)
Molecular Therapy
, vol.19
, Issue.9
, pp. 1737-1746
-
-
Cerullo, V.1
Diaconu, I.2
Kangasniemi, L.3
Rajecki, M.4
Escutenaire, S.5
Koski, A.6
-
185
-
-
0034796870
-
Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy
-
COI: 1:CAS:528:DC%2BD3MXnvF2kuro%3D, PID: 11595690
-
Demaria, S., Volm, M. D., Shapiro, R. L., Yee, H. T., Oratz, R., Formenti, S. C., et al. (2001). Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy. Clinical Cancer Research, 7(10), 3025–3030.
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.10
, pp. 3025-3030
-
-
Demaria, S.1
Volm, M.D.2
Shapiro, R.L.3
Yee, H.T.4
Oratz, R.5
Formenti, S.C.6
-
186
-
-
73349084990
-
Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation
-
COI: 1:CAS:528:DC%2BC3cXhtVWis7Y%3D, PID: 19805669
-
Emens, L. A., Asquith, J. M., Leatherman, J. M., Kobrin, B. J., Petrik, S., Laiko, M., et al. (2009). Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation. Journal of Clinical Oncology, 27(35), 5911–5918. doi:10.1200/JCO.2009.23.3494.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.35
, pp. 5911-5918
-
-
Emens, L.A.1
Asquith, J.M.2
Leatherman, J.M.3
Kobrin, B.J.4
Petrik, S.5
Laiko, M.6
-
187
-
-
84964315493
-
A feasibility study of cyclophosphamide, trastuzumab, and an allogeneic GM-CSF-secreting breast tumor vaccine for HER2+ metastatic breast cancer
-
COI: 1:CAS:528:DC%2BC2cXhslajsrrM, PID: 25116755
-
Chen, G., Gupta, R., Petrik, S., Laiko, M., Leatherman, J. M., Asquith, J. M., et al. (2014). A feasibility study of cyclophosphamide, trastuzumab, and an allogeneic GM-CSF-secreting breast tumor vaccine for HER2+ metastatic breast cancer. Cancer Immunology Research, 2(10), 949–961. doi:10.1158/2326-6066.CIR-14-0058.
-
(2014)
Cancer Immunology Research
, vol.2
, Issue.10
, pp. 949-961
-
-
Chen, G.1
Gupta, R.2
Petrik, S.3
Laiko, M.4
Leatherman, J.M.5
Asquith, J.M.6
-
188
-
-
82255181369
-
Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells
-
COI: 1:CAS:528:DC%2BC3MXhtlKhtrjN, PID: 22028176
-
Pruitt, S. K., Boczkowski, D., de Rosa, N., Haley, N. R., Morse, M. A., Tyler, D. S., et al. (2011). Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells. European Journal of Immunology, 41(12), 3553–3563. doi:10.1002/eji.201141383.
-
(2011)
European Journal of Immunology
, vol.41
, Issue.12
, pp. 3553-3563
-
-
Pruitt, S.K.1
Boczkowski, D.2
de Rosa, N.3
Haley, N.R.4
Morse, M.A.5
Tyler, D.S.6
-
189
-
-
85008348419
-
Abstract P2-15-04: A phase 1/2 study of Ad. p53 DC vaccine with indoximod immunotherapy in metastatic breast cancer. Cancer Res, 75(9 Supplement)
-
Soliman, H. H., Minton, S. E., Ismail-Khan, R., Han, H. S., Vahanian, N. N., Link, C. J., et al. (2015). Abstract P2-15-04: A phase 1/2 study of Ad. p53 DC vaccine with indoximod immunotherapy in metastatic breast cancer. Cancer Res, 75(9 Supplement), P2-15-04-P12-15-04.
-
(2015)
P2-15-04-P12-15-04
-
-
Soliman, H.H.1
Minton, S.E.2
Ismail-Khan, R.3
Han, H.S.4
Vahanian, N.N.5
Link, C.J.6
-
190
-
-
82155168544
-
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
-
COI: 1:CAS:528:DC%2BC38Xms1Cquw%3D%3D, PID: 22123319
-
Hamid, O., Schmidt, H., Nissan, A., Ridolfi, L., Aamdal, S., Hansson, J., et al. (2011). A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma. Journal of Translational Medicine, 9, 204. doi:10.1186/1479-5876-9-204.
-
(2011)
Journal of Translational Medicine
, vol.9
, pp. 204
-
-
Hamid, O.1
Schmidt, H.2
Nissan, A.3
Ridolfi, L.4
Aamdal, S.5
Hansson, J.6
-
191
-
-
84893965118
-
Immune modulation in cancer with antibodies
-
COI: 1:CAS:528:DC%2BC2cXktFeltbo%3D, PID: 24188664
-
Page, D. B., Postow, M. A., Callahan, M. K., Allison, J. P., & Wolchok, J. D. (2014). Immune modulation in cancer with antibodies. Annual Review of Medicine, 65, 185–202. doi:10.1146/annurev-med-092012-112807.
-
(2014)
Annual Review of Medicine
, vol.65
, pp. 185-202
-
-
Page, D.B.1
Postow, M.A.2
Callahan, M.K.3
Allison, J.P.4
Wolchok, J.D.5
-
192
-
-
84902668786
-
Blood mRNA expression profiling predicts survival in patients treated with tremelimumab
-
COI: 1:CAS:528:DC%2BC2cXps1Cmtr4%3D, PID: 24721645
-
Saenger, Y., Magidson, J., Liaw, B., de Moll, E., Harcharik, S., Fu, Y., et al. (2014). Blood mRNA expression profiling predicts survival in patients treated with tremelimumab. Clinical Cancer Research, 20(12), 3310–3318. doi:10.1158/1078-0432.CCR-13-2906.
-
(2014)
Clinical Cancer Research
, vol.20
, Issue.12
, pp. 3310-3318
-
-
Saenger, Y.1
Magidson, J.2
Liaw, B.3
de Moll, E.4
Harcharik, S.5
Fu, Y.6
-
193
-
-
84875132942
-
Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events
-
COI: 1:CAS:528:DC%2BC3sXnvVyju7s%3D, PID: 23521917
-
Shahabi, V., Berman, D., Chasalow, S. D., Wang, L., Tsuchihashi, Z., Hu, B., et al. (2013). Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events. Journal of Translational Medicine, 11, 75. doi:10.1186/1479-5876-11-75.
-
(2013)
Journal of Translational Medicine
, vol.11
, pp. 75
-
-
Shahabi, V.1
Berman, D.2
Chasalow, S.D.3
Wang, L.4
Tsuchihashi, Z.5
Hu, B.6
-
194
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
COI: 1:CAS:528:DC%2BC38XhtV2rs7fN, PID: 22658127
-
Topalian, S. L., Hodi, F. S., Brahmer, J. R., Gettinger, S. N., Smith, D. C., McDermott, D. F., et al. (2012). Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. The New England Journal of Medicine, 366(26), 2443–2454. doi:10.1056/NEJMoa1200690.
-
(2012)
The New England Journal of Medicine
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
195
-
-
85008314033
-
-
Grosso, J., Horak, C. E., Inzunza, D., Cardona, D. M., Simon, J. S., Gupta, A. K., et al. 2013 Association of tumor PD-L1 expression and immune biomarkers with clinical activity in patients (pts) with advanced solid tumors treated with nivolumab (anti-PD-1; BMS-936558; ONO-4538). In Journal of Clinical Oncology, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
Grosso, J., Horak, C. E., Inzunza, D., Cardona, D. M., Simon, J. S., Gupta, A. K., et al. 2013 Association of tumor PD-L1 expression and immune biomarkers with clinical activity in patients (pts) with advanced solid tumors treated with nivolumab (anti-PD-1; BMS-936558; ONO-4538). In Journal of Clinical Oncology, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
-
-
-
196
-
-
85008348422
-
-
Callahan, M. K., Horak, C. E., Curran, M. A., Hollman, T., Schaer, D. A., Yuan, J., et al. 2013 Peripheral and tumor immune correlates in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
Callahan, M. K., Horak, C. E., Curran, M. A., Hollman, T., Schaer, D. A., Yuan, J., et al. 2013 Peripheral and tumor immune correlates in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
-
-
-
197
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
COI: 1:CAS:528:DC%2BC3sXht1ektbrF, PID: 23724867
-
Wolchok, J. D., Kluger, H., Callahan, M. K., Postow, M. A., Rizvi, N. A., Lesokhin, A. M., et al. (2013). Nivolumab plus ipilimumab in advanced melanoma. The New England Journal of Medicine, 369(2), 122–133. doi:10.1056/NEJMoa1302369.
-
(2013)
The New England Journal of Medicine
, vol.369
, Issue.2
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
-
198
-
-
84928342005
-
Peripheral and tumor immune correlates in patients with advanced melanoma treated with nivolumab (anti-PD-1, BMS-936558, ONO-4538) monotherapy or in combination with ipilimumab
-
Postow, M. A., Cardona, D. M., Taube, J. M., Anders, R. A., Taylor, C. R., Wolchok, J. D., et al. (2014). Peripheral and tumor immune correlates in patients with advanced melanoma treated with nivolumab (anti-PD-1, BMS-936558, ONO-4538) monotherapy or in combination with ipilimumab. Journal of Translational Medicine, 12(Suppl 1), O8.
-
(2014)
Journal of Translational Medicine
, vol.12
, pp. O8
-
-
Postow, M.A.1
Cardona, D.M.2
Taube, J.M.3
Anders, R.A.4
Taylor, C.R.5
Wolchok, J.D.6
-
199
-
-
77950258677
-
Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting
-
COI: 1:CAS:528:DC%2BC3cXkvFOns7g%3D, PID: 20143434
-
Ku, G. Y., Yuan, J., Page, D. B., Schroeder, S. E., Panageas, K. S., Carvajal, R. D., et al. (2010). Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting. Cancer, 116(7), 1767–1775.
-
(2010)
Cancer
, vol.116
, Issue.7
, pp. 1767-1775
-
-
Ku, G.Y.1
Yuan, J.2
Page, D.B.3
Schroeder, S.E.4
Panageas, K.S.5
Carvajal, R.D.6
-
200
-
-
85008346168
-
-
Postow, M. A., Yuan, J., Panageas, K., Bogatch, K., Callahan, M., Cheng, M., et al. 2012 Evaluation of the absolute lymphocyte count as a biomarker for melanoma patients treated with the commercially available dose of ipilimumab (3mg/kg). In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 30, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
Postow, M. A., Yuan, J., Panageas, K., Bogatch, K., Callahan, M., Cheng, M., et al. 2012 Evaluation of the absolute lymphocyte count as a biomarker for melanoma patients treated with the commercially available dose of ipilimumab (3mg/kg). In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 30, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
-
-
-
201
-
-
85008355308
-
-
Postow, M. A., Chasalow, S. D., Yuan, J., Kuk, D., Panageas, K. S., Cheng, M., et al. 2013 Pharmacodynamic effect of ipilimumab on absolute lymphocyte count (ALC) and association with overall survival in patients with advanced melanoma. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
Postow, M. A., Chasalow, S. D., Yuan, J., Kuk, D., Panageas, K. S., Cheng, M., et al. 2013 Pharmacodynamic effect of ipilimumab on absolute lymphocyte count (ALC) and association with overall survival in patients with advanced melanoma. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
-
-
-
202
-
-
85008381980
-
-
Schindler, K., Harmankaya, K., Postow, M. A., Frantal, S., Bello, D., Ariyan, C. E., et al. 2013 Pretreatment levels of absolute and relative eosinophil count to improve overall survival (OS) in patients with metastatic melanoma under treatment with ipilimumab, an anti CTLA-4 antibody. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
Schindler, K., Harmankaya, K., Postow, M. A., Frantal, S., Bello, D., Ariyan, C. E., et al. 2013 Pretreatment levels of absolute and relative eosinophil count to improve overall survival (OS) in patients with metastatic melanoma under treatment with ipilimumab, an anti CTLA-4 antibody. In JOURNAL OF CLINICAL ONCOLOGY, (Vol. 31, Vol. 15): AMER SOC CLINICAL ONCOLOGY 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
-
-
-
-
203
-
-
85008327866
-
-
Schindler, K., Harmankaya, K., Kuk, D., Mangana, J., Michielin, O., Hoeller, C., et al. Correlation of absolute and relative eosinophil counts with immune-related adverse events in melanoma patients treated with ipilimumab. In ASCO Annual Meeting Proceedings, 2014 (Vol. 32, pp. 9096, Vol. 15_suppl)
-
Schindler, K., Harmankaya, K., Kuk, D., Mangana, J., Michielin, O., Hoeller, C., et al. Correlation of absolute and relative eosinophil counts with immune-related adverse events in melanoma patients treated with ipilimumab. In ASCO Annual Meeting Proceedings, 2014 (Vol. 32, pp. 9096, Vol. 15_suppl)
-
-
-
-
204
-
-
84907198355
-
Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199
-
PID: 25071121
-
Adams, S., Gray, R. J., Demaria, S., Goldstein, L., Perez, E. A., Shulman, L. N., et al. (2014). Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199. Journal of Clinical Oncology, 32(27), 2959–2966. doi:10.1200/JCO.2013.55.0491.
-
(2014)
Journal of Clinical Oncology
, vol.32
, Issue.27
, pp. 2959-2966
-
-
Adams, S.1
Gray, R.J.2
Demaria, S.3
Goldstein, L.4
Perez, E.A.5
Shulman, L.N.6
-
205
-
-
84875722651
-
Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98
-
COI: 1:CAS:528:DC%2BC3sXltVagtLc%3D, PID: 23341518
-
Loi, S., Sirtaine, N., Piette, F., Salgado, R., Viale, G., Van Eenoo, F., et al. (2013). Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98. Journal of Clinical Oncology, 31(7), 860–867. doi:10.1200/JCO.2011.41.0902.
-
(2013)
Journal of Clinical Oncology
, vol.31
, Issue.7
, pp. 860-867
-
-
Loi, S.1
Sirtaine, N.2
Piette, F.3
Salgado, R.4
Viale, G.5
Van Eenoo, F.6
-
206
-
-
79956329617
-
Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer
-
PID: 21483002
-
Mahmoud, S. M., Paish, E. C., Powe, D. G., Macmillan, R. D., Grainge, M. J., Lee, A. H., et al. (2011). Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer. Journal of Clinical Oncology, 29(15), 1949–1955. doi:10.1200/JCO.2010.30.5037.
-
(2011)
Journal of Clinical Oncology
, vol.29
, Issue.15
, pp. 1949-1955
-
-
Mahmoud, S.M.1
Paish, E.C.2
Powe, D.G.3
Macmillan, R.D.4
Grainge, M.J.5
Lee, A.H.6
|