Ii-Key/HER-2/neu(776-790) hybrid peptides induce more effective immunological responses over the native peptide in lymphocyte cultures from patients with HER-2/neu+ tumors

Cancer Immunology, Immunotherapy

Volumn 56, Issue 5, 2007, Pages 601-613

  Sotiriadou, Nectaria N ^a   Kallinteris, Nikoletta L ^b   Gritzapis, Angelos D ^a   Voutsas, Ioannis F ^a   Papamichail, Michael ^a   Von Hofe, Eric ^b   Humphreys, Robert E ^b   Pavlis, Theodoros ^c   Perez, Sonia A ^a   Baxevanis, Constantin N ^a  

^a SAINT SAVVAS HOSPITAL   (Greece)

^b Antigen Express Inc   (United States)

^c Surgical Clinic Mitera Hospital   (Greece)

Author keywords

Cancer vaccines; CTL; HER 2 neu peptides; Ii Key hybrid peptides; T helper cells

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITOPE; GAMMA INTERFERON; HYBRID PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER IMMUNIZATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG EFFICACY; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOGENICITY; LUNG CANCER; LYMPHOCYTE CULTURE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; OVARY CANCER; PANCREAS CANCER; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROSTATE CANCER; SCID MOUSE; STATISTICAL SIGNIFICANCE; TUMOR CELL; TUMOR MODEL; XENOGRAFT;

ANTIGEN PRESENTATION; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; CANCER VACCINES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES, T-LYMPHOCYTE; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LYMPHOCYTE ACTIVATION; PEPTIDE FRAGMENTS; RECEPTOR, ERBB-2; RECOMBINANT PROTEINS; T-LYMPHOCYTE SUBSETS;

EID: 33847405324     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-006-0213-z     Document Type: Article

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