Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Shahabi, Vafa ^a   Berman, David ^a   Chasalow, Scott D ^a   Wang, Lisu ^a   Tsuchihashi, Zenta ^a   Hu, Beihong ^a   Panting, Lisa ^a   Jure Kunkel, Maria ^a   Ji, Rui Ru ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Adverse events; Biomarkers; Colitis; Diarrhea; Gastrointestinal; Gene expression; Gene expression profiling; GI irAE; Ipilimumab; Metastatic melanoma

Indexed keywords

BIOLOGICAL MARKER; BUDESONIDE; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CD37 ANTIGEN; CD4 ANTIGEN; CELLUBREVIN; DEFENSIN; GLYCOSYLPHOSPHATIDYLINOSITOL; IPILIMUMAB; LACTOFERRIN; MYELOPEROXIDASE; RAC2 PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; ALLOANTIGEN; CD177 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; TUMOR MARKER;

ADVANCED CANCER; ANTIGEN EXPRESSION; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CELL CYCLE; CELL MIGRATION; COLITIS; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG ERUPTION; DRUG SAFETY; GASTROINTESTINAL SYMPTOM; GENE EXPRESSION PROFILING; HUMAN; MAJOR CLINICAL STUDY; MELANOMA; MULTICENTER STUDY; NEUTROPHIL; NEUTROPHIL COUNT; PHASE 2 CLINICAL TRIAL; PROTEIN EXPRESSION; PROTEIN FOLDING; BLOOD; CLINICAL TRIAL; DRUG EFFECTS; GASTROINTESTINAL TRACT; GENE EXPRESSION REGULATION; GENETICS; IMMUNE SYSTEM; LEUKOCYTE COUNT; METABOLISM; PATHOLOGY; RANDOMIZED CONTROLLED TRIAL; RECEIVER OPERATING CHARACTERISTIC; REPRODUCIBILITY; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; GASTROINTESTINAL TRACT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GPI-LINKED PROTEINS; HUMANS; IMMUNE SYSTEM; IMMUNOGLOBULINS; ISOANTIGENS; LEUKOCYTE COUNT; MELANOMA; NEUTROPHILS; RECEPTORS, CELL SURFACE; REPRODUCIBILITY OF RESULTS; ROC CURVE; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 84875132942     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-75     Document Type: Article

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