Enteric glial cells are susceptible to Clostridium difficile toxin B

Cellular and Molecular Life Sciences

Volumn 74, Issue 8, 2017, Pages 1527-1551

  Fettucciari, Katia ^a   Ponsini, Pamela ^a   Gioè, Davide ^a   Macchioni, Lara ^a   Palumbo, Camilla ^b   Antonelli, Elisabetta ^c   Coaccioli, Stefano ^a   Villanacci, Vincenzo ^d   Corazzi, Lanfranco ^a   Marconi, Pierfrancesco ^a   Bassotti, Gabrio ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c Perugia General Hospital   (Italy)

^d SPEDALI CIVILI   (Italy)

Author keywords

Apoptosis; Cell cycle arrest; Clostridium difficile toxin B (TcdB); Enteric glial cells (EGCs); Glial cell derived neurotrophic factor (GDNF); Proinflammatory cytokines; Rac1 glucosylation

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; CASPASE INHIBITOR; CLOSTRIDIUM DIFFICILE TOXIN B; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; GAMMA INTERFERON; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GUANOSINE TRIPHOSPHATASE; P21 ACTIVATED KINASE 1; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN CDC42; PROTEIN P27; RAC1 PROTEIN; RHO FACTOR; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR; BACTERIAL PROTEIN; BACTERIAL TOXIN; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE;

ACTIN FILAMENT; ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOREGULATION; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL STRUCTURE; CLOSTRIDIUM DIFFICILE INFECTION; COLON CELL; CONTROLLED STUDY; CYTOTOXICITY; DISEASE PREDISPOSITION; DOWN REGULATION; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GLIA CELL; GLYCOSYLATION; HOMEOSTASIS; IMMUNE RESPONSE; IN VITRO STUDY; INFLAMMATION; INTESTINE CELL; M PHASE CELL CYCLE CHECKPOINT; NERVE CELL; NONHUMAN; PATHOGENESIS; PEPTOCLOSTRIDIUM DIFFICILE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION; ANIMAL; CELL CYCLE CHECKPOINT; CELL LINE; GASTROINTESTINAL TRACT; GLIA; INNERVATION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; PSEUDOMEMBRANOUS COLITIS;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CELL CYCLE CHECKPOINTS; CELL LINE; CLOSTRIDIUM DIFFICILE; ENTEROCOLITIS, PSEUDOMEMBRANOUS; GASTROINTESTINAL TRACT; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; NEUROGLIA; RATS;

EID: 84997503278     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-016-2426-4     Document Type: Article

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