Systemic dissemination of Clostridium difficile toxins A and B is associated with severe, fatal disease in animal models

Journal of Infectious Diseases

Volumn 205, Issue 3, 2012, Pages 384-391

  Steele, Jennifer ^a   Chen, Kevin ^a   Sun, Xingmin ^a   Zhang, Yongrong ^a,b   Wang, Haiying ^a,c   Tzipori, Saul ^a   Feng, Hanping ^a  

^a TUFTS UNIVERSITY   (United States)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; CXCL1 CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; NEUTRALIZING ANTIBODY; RAC1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FLUID; CELL INDEX; CELL ROUNDING; CELLULAR PARAMETERS; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; CYTOTOXICITY TEST; DISEASE ASSOCIATION; DISEASE SEVERITY; GLYCOSYLATION; MOUSE; NONHUMAN; PIGLET; PRIORITY JOURNAL; TOXEMIA;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTITOXINS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BODY FLUIDS; CELL SURVIVAL; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; CYTOKINES; CYTOLOGICAL TECHNIQUES; DISEASE MODELS, ANIMAL; ENTEROTOXINS; MICE; MICE, INBRED C57BL; SWINE; TOXEMIA;

EID: 84862907897     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir748     Document Type: Article

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