메뉴 건너뛰기




Volumn 280, Issue 2 43-2, 2001, Pages

Microbes and microbial toxins: Paradigms for microbial-mucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins

Author keywords

Intestinal inflammation; Mast cells; Neuropeptides; Neutrophils; Rho proteins

Indexed keywords

ACTIN; BACTERIAL TOXIN; CLOSTRIDIUM DIFFICILE TOXIN; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROPEPTIDE; PROTEIN CDC42; RAC PROTEIN; REACTIVE OXYGEN METABOLITE; RHO A PROTEIN; RHO FACTOR; UNCLASSIFIED DRUG;

EID: 0034999642     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2001.280.2.g178     Document Type: Review
Times cited : (179)

References (25)
  • 1
    • 0028790399 scopus 로고
    • Monoglucosylation of low-molecular-mass GTP-binding Rho proteins by clostridial cytotoxin
    • Aktories K and Just I. Monoglucosylation of low-molecular-mass GTP-binding Rho proteins by clostridial cytotoxin. Trends Cell Biol 5: 441-443, 1995.
    • (1995) Trends Cell Biol , vol.5 , pp. 441-443
    • Aktories, K.1    Just, I.2
  • 3
    • 0030896270 scopus 로고    scopus 로고
    • Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats
    • Castagliuolo I, Keates AC, Qiu BS, Kelly CP, Nikulasson ST, Leeman SE, and Pothoulakis C. Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proc Natl Acad Sci USA 94: 4788-4793, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4788-4793
    • Castagliuolo, I.1    Keates, A.C.2    Qiu, B.S.3    Kelly, C.P.4    Nikulasson, S.T.5    Leeman, S.E.6    Pothoulakis, C.7
  • 9
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science 279: 509-514, 1998.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 11
    • 0031887901 scopus 로고    scopus 로고
    • Chimeric clostridial cytotoxins: Identification of the N-terminal region involved in protein substrate recognition
    • Hofmann F, Busch C, and Aktories K. Chimeric clostridial cytotoxins: identification of the N-terminal region involved in protein substrate recognition. Infect Immun 66: 1076-1081, 1998.
    • (1998) Infect Immun , vol.66 , pp. 1076-1081
    • Hofmann, F.1    Busch, C.2    Aktories, K.3
  • 12
    • 0030891386 scopus 로고    scopus 로고
    • Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin
    • Hofmann F, Busch C, Prepens U, Just I, and Aktories K. Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin. J Biol Chem 272: 11074-11078, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 11074-11078
    • Hofmann, F.1    Busch, C.2    Prepens, U.3    Just, I.4    Aktories, K.5
  • 15
    • 0022525082 scopus 로고
    • Cell surface binding site for Clostridium difficile enterotoxin: Evidence for a glycoconjugate containing the sequence Galα1-3Galβ1-4 GlcNAc
    • Krivan HC, Clark GF, Smith DF, and Wilkins TD. Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Galα1-3Galβ1-4 GlcNAc. Infect Immun 53: 573-581, 1986.
    • (1986) Infect Immun , vol.53 , pp. 573-581
    • Krivan, H.C.1    Clark, G.F.2    Smith, D.F.3    Wilkins, T.D.4
  • 17
    • 0033911836 scopus 로고    scopus 로고
    • Genetics of Clostridium difficile toxin
    • edited by Aktories K and Wilkins TC. Berlin: Springer
    • Moncrief JS and Wilkins TD. Genetics of Clostridium difficile toxin. In: Clostridium difficile, edited by Aktories K and Wilkins TC. Berlin: Springer, 2000, p. 35-54.
    • (2000) Clostridium Difficile , pp. 35-54
    • Moncrief, J.S.1    Wilkins, T.D.2
  • 18
    • 0028013431 scopus 로고
    • CP-96,345, a specific substance P receptor antagonist inhibits rat intestinal responses to Clostridium difficile toxin A, but not cholera toxin
    • Pothoulakis C, Castagliuolo I, LaMont JT, Jaffer A, O'Keane JC, Snider M, and Leeman SE. CP-96,345, a specific substance P receptor antagonist inhibits rat intestinal responses to Clostridium difficile toxin A, but not cholera toxin. Proc Natl Acad Sci USA 91: 947-951, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 947-951
    • Pothoulakis, C.1    Castagliuolo, I.2    LaMont, J.T.3    Jaffer, A.4    O'Keane, J.C.5    Snider, M.6    Leeman, S.E.7
  • 22
    • 0024428291 scopus 로고
    • Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum. Role of prostaglandins and leukotrienes
    • Triadafilopoulos G, Pothoulakis C, Weiss R, Giampaolo C, and LaMont JT. Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum. Role of prostaglandins and leukotrienes. Gastroenterology 97: 1186-1192, 1989.
    • (1989) Gastroenterology , vol.97 , pp. 1186-1192
    • Triadafilopoulos, G.1    Pothoulakis, C.2    Weiss, R.3    Giampaolo, C.4    LaMont, J.T.5
  • 23
    • 0030271882 scopus 로고    scopus 로고
    • Large clostridial cytotoxins - A family of glucosyltransferases modifying small GTP-binding proteins
    • Von Eichel-Streiber CV, Boquet P, and Sauerborn M. Large clostridial cytotoxins - a family of glucosyltransferases modifying small GTP-binding proteins. Trends Microbiol 4: 375-382, 1996.
    • (1996) Trends Microbiol , vol.4 , pp. 375-382
    • Von Eichel-Streiber, C.V.1    Boquet, P.2    Sauerborn, M.3
  • 25
    • 0031967123 scopus 로고    scopus 로고
    • Mast cell involvement in Clostridium difficile toxin A-induced intestinal fluid secretion and neutrophil recruitment in mice
    • Wershil B, Castagliuolo I, and Pothoulakis C. Mast cell involvement in Clostridium difficile toxin A-induced intestinal fluid secretion and neutrophil recruitment in mice. Gastroenterology 114: 956-964, 1998.
    • (1998) Gastroenterology , vol.114 , pp. 956-964
    • Wershil, B.1    Castagliuolo, I.2    Pothoulakis, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.