메뉴 건너뛰기




Volumn 119, Issue 1, 2000, Pages 139-150

Clostridium difficile toxin A causes early damage to mitochondria in cultured cells

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM TOXIN;

EID: 0034234809     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2000.8526     Document Type: Article
Times cited : (102)

References (47)
  • 2
    • 0025649278 scopus 로고
    • The cytotoxic action of diphtheria toxin and its degradation in intact vero cells are inhibited by bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase
    • Umata T, Moriyama Y, Futai M, Mekada E. The cytotoxic action of diphtheria toxin and its degradation in intact vero cells are inhibited by bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase. J Biol Chem 1990;265:21940-21945.
    • (1990) J Biol Chem , vol.265 , pp. 21940-21945
    • Umata, T.1    Moriyama, Y.2    Futai, M.3    Mekada, E.4
  • 6
    • 0022525082 scopus 로고
    • Cell surface binding site for Clostridium difficile enterotoxin: Evidence for a glycoconjugate containing the sequence Gal alpha 1-3Gal beta 1-4GlcNAc
    • Krivan HC, Clark GF, Smith DF, Wilkins TD. Cell surface binding site for Clostridium difficile enterotoxin: Evidence for a glycoconjugate containing the sequence Gal alpha 1-3Gal beta 1-4GlcNAc. Infect Immun 1986;53:573-581.
    • (1986) Infect Immun , vol.53 , pp. 573-581
    • Krivan, H.C.1    Clark, G.F.2    Smith, D.F.3    Wilkins, T.D.4
  • 8
    • 0021108235 scopus 로고
    • Internalization of Clostridium difficile cytotoxin into cultured human lung fibroblasts
    • Florin I, Thelestam M. Internalization of Clostridium difficile cytotoxin into cultured human lung fibroblasts. Biochim Biophys Acta 1983;763:383-392.
    • (1983) Biochim Biophys Acta , vol.763 , pp. 383-392
    • Florin, I.1    Thelestam, M.2
  • 9
    • 0023269823 scopus 로고
    • Cellular internalisation of Clostridium difficile toxin A
    • Henriques B, Florin I, Thelestam M. Cellular internalisation of Clostridium difficile toxin A. Microb Pathog 1987;2:455-463.
    • (1987) Microb Pathog , vol.2 , pp. 455-463
    • Henriques, B.1    Florin, I.2    Thelestam, M.3
  • 10
    • 0024204607 scopus 로고
    • Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers
    • Hecht G, Pothoulakis C, LaMont JT, Madara JL. Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers. J Clin Invest 1988;82:1516-1524.
    • (1988) J Clin Invest , vol.82 , pp. 1516-1524
    • Hecht, G.1    Pothoulakis, C.2    LaMont, J.T.3    Madara, J.L.4
  • 12
    • 0030946064 scopus 로고    scopus 로고
    • Tight junction proteins form large complexes and associate with the cytoskeleton in an ATP depletion model for reversible junction assembly
    • Tsukamoto T, Nigam SK. Tight junction proteins form large complexes and associate with the cytoskeleton in an ATP depletion model for reversible junction assembly. J Biol Chem 1997; 272:16133-16139.
    • (1997) J Biol Chem , vol.272 , pp. 16133-16139
    • Tsukamoto, T.1    Nigam, S.K.2
  • 13
    • 85031592870 scopus 로고    scopus 로고
    • Early internalization and mitochondrial localization of Clostridium difficile toxin A in chinese hamster ovary (CHO) cells
    • LaMont JT, He D, Pothoulakis C, Hagen SJ, Chen M, Medina ND. Early internalization and mitochondrial localization of Clostridium difficile toxin A in chinese hamster ovary (CHO) cells (abstr). Gastroenterology 1999;116:G3286.
    • (1999) Gastroenterology , vol.116
    • LaMont, J.T.1    He, D.2    Pothoulakis, C.3    Hagen, S.J.4    Chen, M.5    Medina, N.D.6
  • 14
    • 0025893128 scopus 로고
    • Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein
    • Pothoulakis C, LaMont JT, Eglow R, Gao N, Rubins JB, Theoharides TC, Dickey BF. Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein. J Clin Invest 1991;88:119-125.
    • (1991) J Clin Invest , vol.88 , pp. 119-125
    • Pothoulakis, C.1    LaMont, J.T.2    Eglow, R.3    Gao, N.4    Rubins, J.B.5    Theoharides, T.C.6    Dickey, B.F.7
  • 16
    • 0030745869 scopus 로고    scopus 로고
    • Correlated flow cytometric analysis of terminal events in apoptosis reveals the absence of some changes in some model systems
    • Frey T. Correlated flow cytometric analysis of terminal events in apoptosis reveals the absence of some changes in some model systems. Cytometry 1997;28:253-263.
    • (1997) Cytometry , vol.28 , pp. 253-263
    • Frey, T.1
  • 17
    • 0027944204 scopus 로고
    • Use of an ATP bioluminescent assay to evaluate viability of Pneumocystis carinii from rats
    • Chen F, Cushion MT. Use of an ATP bioluminescent assay to evaluate viability of Pneumocystis carinii from rats. J Clin Microbiol 1994;32:2791-2800.
    • (1994) J Clin Microbiol , vol.32 , pp. 2791-2800
    • Chen, F.1    Cushion, M.T.2
  • 18
    • 0027499070 scopus 로고
    • The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity
    • Crouch SP, Kozlowski R, Slater KJ, Fletcher J. The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity. J Immunol Methods 1993;160:81-88.
    • (1993) J Immunol Methods , vol.160 , pp. 81-88
    • Crouch, S.P.1    Kozlowski, R.2    Slater, K.J.3    Fletcher, J.4
  • 19
    • 0030917004 scopus 로고    scopus 로고
    • Mitochondrial membrane potential measurement in rat cerebellar neurons by flow cytometry
    • Sureda FX, Escubedo E, Gabriel C, Comas J, Camarasa J, Camins A. Mitochondrial membrane potential measurement in rat cerebellar neurons by flow cytometry. Cytometry 1997;28:74-80.
    • (1997) Cytometry , vol.28 , pp. 74-80
    • Sureda, F.X.1    Escubedo, E.2    Gabriel, C.3    Comas, J.4    Camarasa, J.5    Camins, A.6
  • 20
    • 0029665620 scopus 로고    scopus 로고
    • Limitations on the use of dihydrorhodamine 123 for flow cytometric analysis of the neutrophil respiratory burst
    • van Pelt LJ, van Zwieten R, Weening RS, Roos D, Verhoeven AJ, Bolscher BGJM. Limitations on the use of dihydrorhodamine 123 for flow cytometric analysis of the neutrophil respiratory burst. J Immunol Methods 1996;191:187-196.
    • (1996) J Immunol Methods , vol.191 , pp. 187-196
    • Van Pelt, L.J.1    Van Zwieten, R.2    Weening, R.S.3    Roos, D.4    Verhoeven, A.J.5    Bolscher, B.6
  • 21
    • 0015590118 scopus 로고
    • Mode of mitochondrial formation in HeLa cells
    • Storrie B, Attardi G. Mode of mitochondrial formation in HeLa cells. J Cell Biol 1973;56:833-838.
    • (1973) J Cell Biol , vol.56 , pp. 833-838
    • Storrie, B.1    Attardi, G.2
  • 22
    • 0028902781 scopus 로고
    • Cloning of rat grp75, an hsp70-family member, and its expression in normal and ischemic brain
    • Massa SM. Cloning of rat grp75, an hsp70-family member, and its expression in normal and ischemic brain. J Neurosci Res 1995; 40:807-819.
    • (1995) J Neurosci Res , vol.40 , pp. 807-819
    • Massa, S.M.1
  • 23
    • 0029151366 scopus 로고
    • Purification and assay of recombinant C3 transferase
    • Dillon ST, Feig LA. Purification and assay of recombinant C3 transferase. Methods Enzymol 1995;256:174-184.
    • (1995) Methods Enzymol , vol.256 , pp. 174-184
    • Dillon, S.T.1    Feig, L.A.2
  • 24
    • 0025602433 scopus 로고
    • ADP-ribosylation of the rho/rac gene products by botulinum ADP-ribosyltransferase: Identity of the enzyme and effects on protein and cell functions
    • Narumiya S, Morii N, Sekine A, Kozaki S. ADP-ribosylation of the rho/rac gene products by botulinum ADP-ribosyltransferase: Identity of the enzyme and effects on protein and cell functions. J Physiol Paris 1990;84:267-272.
    • (1990) J Physiol Paris , vol.84 , pp. 267-272
    • Narumiya, S.1    Morii, N.2    Sekine, A.3    Kozaki, S.4
  • 26
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281:1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 27
    • 0029925862 scopus 로고    scopus 로고
    • Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: Role of extracellular adenosine and actin polymerization
    • Bengtsson T, Zalavary S, Stendahl O, Grenegard M. Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: Role of extracellular adenosine and actin polymerization. Blood 1996;87:4411-4423.
    • (1996) Blood , vol.87 , pp. 4411-4423
    • Bengtsson, T.1    Zalavary, S.2    Stendahl, O.3    Grenegard, M.4
  • 30
    • 0032496143 scopus 로고    scopus 로고
    • Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
    • Cai J, Yang J, Jones DP. Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J Biol Chem 1998;273: 11401-11404.
    • (1998) J Biol Chem , vol.273 , pp. 11401-11404
    • Cai, J.1    Yang, J.2    Jones, D.P.3
  • 31
    • 0031695576 scopus 로고    scopus 로고
    • Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion
    • Gopalakrishnan S, Raman N, Atkinson SJ, Marrs JA. Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion. Am J Physiol 1998;275:C798-809.
    • (1998) Am J Physiol , vol.275
    • Gopalakrishnan, S.1    Raman, N.2    Atkinson, S.J.3    Marrs, J.A.4
  • 32
    • 85031589723 scopus 로고    scopus 로고
    • Clostridium difficile toxin a-induced MAP kinase activation mediates IL-8 production and cell necrosis in human moncytes
    • Warny M, Keates AC, Keates S, Qamar A, Castagliuolo I, Pothoulakis C. Clostridium difficile toxin A-induced MAP kinase activation mediates IL-8 production and cell necrosis in human moncytes (abstr). Gastroenterology 1999;116:G3242.
    • (1999) Gastroenterology , vol.116
    • Warny, M.1    Keates, A.C.2    Keates, S.3    Qamar, A.4    Castagliuolo, I.5    Pothoulakis, C.6
  • 33
    • 0033041916 scopus 로고    scopus 로고
    • Reactive oxygen species - Induced molecular damage and its application in pathology
    • Toyokuni S. Reactive oxygen species-induced molecular damage and its application in pathology. Pathol Int 1999;49:91-102.
    • (1999) Pathol Int , vol.49 , pp. 91-102
    • Toyokuni, S.1
  • 35
    • 0027328056 scopus 로고
    • Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF
    • Schulze-Osthoff K, Beyaert R, Vandevoorde V, Haegeman G, Fiers W. Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF. EMBO J 1993;12: 3095-3104.
    • (1993) EMBO J , vol.12 , pp. 3095-3104
    • Schulze-Osthoff, K.1    Beyaert, R.2    Vandevoorde, V.3    Haegeman, G.4    Fiers, W.5
  • 36
    • 0032913592 scopus 로고    scopus 로고
    • Participation of reactive oxygen metabolites in Clostridium difficile town A-induced enteritis in rats
    • Qiu B, Pothoulakis C, Castagliuolo I, Nikulasson S, LaMont JT. Participation of reactive oxygen metabolites in Clostridium difficile town A-induced enteritis in rats. Am J Physiol 1999;276: G485-G490.
    • (1999) Am J Physiol , vol.276
    • Qiu, B.1    Pothoulakis, C.2    Castagliuolo, I.3    Nikulasson, S.4    LaMont, J.T.5
  • 38
    • 0032930160 scopus 로고    scopus 로고
    • Monocytic cell necrosis is mediated by potassium depletion and caspase-like proteases
    • Warny M, Kelly CP. Monocytic cell necrosis is mediated by potassium depletion and caspase-like proteases. Am J Physiol 1999;276:C717-724.
    • (1999) Am J Physiol , vol.276
    • Warny, M.1    Kelly, C.P.2
  • 39
    • 0032425435 scopus 로고    scopus 로고
    • Effect of Clostridium difficile toxin A on human colonic lamina propria cells: Early loss of macrophages followed by T-cell apoptosis
    • Mahida YR, Galvin A, Makh S, Hyde S, Sanfilippo L, Borriello SP, Sewell HF. Effect of Clostridium difficile toxin A on human colonic lamina propria cells: Early loss of macrophages followed by T-cell apoptosis. Infect Immun 1998;66:5462-5469.
    • (1998) Infect Immun , vol.66 , pp. 5462-5469
    • Mahida, Y.R.1    Galvin, A.2    Makh, S.3    Hyde, S.4    Sanfilippo, L.5    Borriello, S.P.6    Sewell, H.F.7
  • 41
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace DC. Mitochondrial diseases in man and mouse. Science 1999;283:1482-1488.
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 42
    • 0031034563 scopus 로고    scopus 로고
    • Controlling cell death
    • Golstein P. Controlling cell death. Science 1997;275:1081-1082.
    • (1997) Science , vol.275 , pp. 1081-1082
    • Golstein, P.1
  • 43
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998;60:619-642.
    • (1998) Annu Rev Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 45
    • 0018917908 scopus 로고
    • Action of bacterial lipopolysaccharide on the respiration of mouse liver mitochondria
    • McGivney A, Bradley SG. Action of bacterial lipopolysaccharide on the respiration of mouse liver mitochondria. Infect Immun 1980; 27:102-106.
    • (1980) Infect Immun , vol.27 , pp. 102-106
    • McGivney, A.1    Bradley, S.G.2
  • 46
    • 0028233630 scopus 로고
    • A novel dodecadepsipeptide, cereulide, isolated from bacillus cereus causes vacuole formation in HEp-2 cells
    • Agata N, Mori M, Ohta M, Suwan S, Ohtani I, Isobe M. A novel dodecadepsipeptide, cereulide, isolated from Bacillus cereus causes vacuole formation in HEp-2 cells. FEMS Microbiol Lett 1994;121:31-34.
    • (1994) FEMS Microbiol Lett , vol.121 , pp. 31-34
    • Agata, N.1    Mori, M.2    Ohta, M.3    Suwan, S.4    Ohtani, I.5    Isobe, M.6
  • 47
    • 0006534562 scopus 로고    scopus 로고
    • Vacuolating cytotoxin purified from Helicobacter pylori causes mitochondrial damage in human gastric cells
    • Kimura M, Goto S, Wada A, Yahiro K, Niidome T, Hatakeyama T, Aoyagi H, Hirayamat, Kondo T. Vacuolating cytotoxin purified from Helicobacter pylori causes mitochondrial damage in human gastric cells. Microb Pathog 1999;26:45-52.
    • (1999) Microb Pathog , vol.26 , pp. 45-52
    • Kimura, M.1    Goto, S.2    Wada, A.3    Yahiro, K.4    Niidome, T.5    Hatakeyama, T.6    Aoyagi, H.7    Kondo, T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.