메뉴 건너뛰기




Volumn 81, Issue 1, 2017, Pages 9-20

The Role of Genes, Stress, and Dopamine in the Development of Schizophrenia

Author keywords

Dopamine; Etiology; Genetics; Neuroimaging; PET; Prodrome; Psychosis; Schizophrenia; Stress

Indexed keywords

DOPAMINE; DOPAMINE 2 RECEPTOR; NEUROTRANSMITTER; DRD2 PROTEIN, HUMAN;

EID: 84997285715     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2016.07.014     Document Type: Review
Times cited : (415)

References (135)
  • 1
    • 0017079279 scopus 로고
    • The dopamine hypothesis of schizophrenia: A review
    • 1 Meltzer, H.Y., Stahl, S.M., The dopamine hypothesis of schizophrenia: A review. Schizophr Bull 2 (1976), 19–76.
    • (1976) Schizophr Bull , vol.2 , pp. 19-76
    • Meltzer, H.Y.1    Stahl, S.M.2
  • 2
    • 0026070134 scopus 로고
    • Dopamine in schizophrenia: A review and reconceptualization
    • 2 Davis, K.L., Kahn, R.S., Ko, G., Davidson, M., Dopamine in schizophrenia: A review and reconceptualization. Am J Psychiatry 148 (1991), 1474–1486.
    • (1991) Am J Psychiatry , vol.148 , pp. 1474-1486
    • Davis, K.L.1    Kahn, R.S.2    Ko, G.3    Davidson, M.4
  • 4
    • 0014770992 scopus 로고
    • The phenomenology of experimentally induced amphetamine psychosis–Preliminary observations
    • 4 Angrist, B.M., Gershon, S., The phenomenology of experimentally induced amphetamine psychosis–Preliminary observations. Biol Psychiatry 2 (1970), 95–107.
    • (1970) Biol Psychiatry , vol.2 , pp. 95-107
    • Angrist, B.M.1    Gershon, S.2
  • 5
    • 84965259735 scopus 로고
    • Amphetamine psychosis
    • 5 Connell, P., Amphetamine psychosis. Br Med J, 1(5018), 1957, 582.
    • (1957) Br Med J , vol.1 , Issue.5018 , pp. 582
    • Connell, P.1
  • 6
    • 78651116398 scopus 로고
    • Effect of chlorpromazine or haloperidol on formation of 3methoxytyramine and normetanephrine in mouse brain
    • 6 Carlsson, A., Lindqvist, M., Effect of chlorpromazine or haloperidol on formation of 3methoxytyramine and normetanephrine in mouse brain. Acta Pharmacol Toxicol (Copenh) 20 (1963), 140–144.
    • (1963) Acta Pharmacol Toxicol (Copenh) , vol.20 , pp. 140-144
    • Carlsson, A.1    Lindqvist, M.2
  • 7
    • 0016592484 scopus 로고
    • Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons
    • 7 Seeman, P., Lee, T., Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 188 (1975), 1217–1219.
    • (1975) Science , vol.188 , pp. 1217-1219
    • Seeman, P.1    Lee, T.2
  • 8
    • 0018841942 scopus 로고
    • Elevation of brain neuroleptic/dopamine receptors in schizophrenia
    • 8 Lee, T., Seeman, P., Elevation of brain neuroleptic/dopamine receptors in schizophrenia. Am J Psychiatry 137 (1980), 191–197.
    • (1980) Am J Psychiatry , vol.137 , pp. 191-197
    • Lee, T.1    Seeman, P.2
  • 9
    • 0034608741 scopus 로고    scopus 로고
    • Schizophrenia: More dopamine, more D2 receptors
    • 9 Seeman, P., Kapur, S., Schizophrenia: More dopamine, more D2 receptors. Proc Natl Acad Sci U S A 97 (2000), 7673–7675.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7673-7675
    • Seeman, P.1    Kapur, S.2
  • 10
    • 84888074554 scopus 로고    scopus 로고
    • Molecular imaging as a guide for the treatment of central nervous system disorders
    • 10 Kim, E., Howes, O.D., Kapur, S., Molecular imaging as a guide for the treatment of central nervous system disorders. Dialogues Clin Neurosci 15 (2013), 315–328.
    • (2013) Dialogues Clin Neurosci , vol.15 , pp. 315-328
    • Kim, E.1    Howes, O.D.2    Kapur, S.3
  • 11
    • 84874509464 scopus 로고    scopus 로고
    • Striatal dopamine transporter availability in drug-naive patients with schizophrenia: A case-control SPECT study with [(99m)Tc]-TRODAT-1 and a meta-analysis
    • 11 Chen, K.C., Yang, Y.K., Howes, O., Lee, I.H., Landau, S., Yeh, T.L., et al. Striatal dopamine transporter availability in drug-naive patients with schizophrenia: A case-control SPECT study with [(99m)Tc]-TRODAT-1 and a meta-analysis. Schizophr Bull 39 (2013), 378–386.
    • (2013) Schizophr Bull , vol.39 , pp. 378-386
    • Chen, K.C.1    Yang, Y.K.2    Howes, O.3    Lee, I.H.4    Landau, S.5    Yeh, T.L.6
  • 13
    • 0035863172 scopus 로고    scopus 로고
    • Vesicular monoamine transporter concentrations in bipolar disorder type I, schizophrenia, and healthy subjects
    • 13 Zubieta, J.K., Taylor, S.F., Huguelet, P., Koeppe, R.A., Kilbourn, M.R., Frey, K.A., Vesicular monoamine transporter concentrations in bipolar disorder type I, schizophrenia, and healthy subjects. Biol Psychiatry 49 (2001), 110–116.
    • (2001) Biol Psychiatry , vol.49 , pp. 110-116
    • Zubieta, J.K.1    Taylor, S.F.2    Huguelet, P.3    Koeppe, R.A.4    Kilbourn, M.R.5    Frey, K.A.6
  • 14
    • 84890525629 scopus 로고    scopus 로고
    • Midbrain dopamine function in schizophrenia and depression: A post-mortem and positron emission tomographic imaging study
    • 14 Howes, O.D., Williams, M., Ibrahim, K., Leung, G., Egerton, A., McGuire, P.K., Turkheimer, F., Midbrain dopamine function in schizophrenia and depression: A post-mortem and positron emission tomographic imaging study. Brain 136 (2013), 3242–3251.
    • (2013) Brain , vol.136 , pp. 3242-3251
    • Howes, O.D.1    Williams, M.2    Ibrahim, K.3    Leung, G.4    Egerton, A.5    McGuire, P.K.6    Turkheimer, F.7
  • 15
    • 84900828695 scopus 로고    scopus 로고
    • Stress-induced dopamine response in subjects at clinical high risk for schizophrenia with and without concurrent cannabis use
    • 15 Mizrahi, R., Kenk, M., Suridjan, I., Boileau, I., George, T.P., McKenzie, K., et al. Stress-induced dopamine response in subjects at clinical high risk for schizophrenia with and without concurrent cannabis use. Neuropsychopharmacology 39 (2013), 1479–1489.
    • (2013) Neuropsychopharmacology , vol.39 , pp. 1479-1489
    • Mizrahi, R.1    Kenk, M.2    Suridjan, I.3    Boileau, I.4    George, T.P.5    McKenzie, K.6
  • 16
    • 84865625024 scopus 로고    scopus 로고
    • Dopaminergic neurotransmission in patients with schizophrenia in relation to positive and negative symptoms
    • 16 Pogarell, O., Koch, W., Karch, S., Dehning, S., Müller, N., Tatsch, K., et al. Dopaminergic neurotransmission in patients with schizophrenia in relation to positive and negative symptoms. Pharmacopsychiatry 45:suppl 1 (2012), S36–S41.
    • (2012) Pharmacopsychiatry , vol.45 , pp. S36-S41
    • Pogarell, O.1    Koch, W.2    Karch, S.3    Dehning, S.4    Müller, N.5    Tatsch, K.6
  • 17
    • 77649197534 scopus 로고    scopus 로고
    • Increased synaptic dopamine function in associative regions of the striatum in schizophrenia
    • 17 Kegeles, L.S., Abi-Dargham, A., Frankle, W.G., Gil, R., Cooper, T.B., Slifstein, M., et al. Increased synaptic dopamine function in associative regions of the striatum in schizophrenia. Arch Gen Psychiatry 67 (2010), 231–239.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 231-239
    • Kegeles, L.S.1    Abi-Dargham, A.2    Frankle, W.G.3    Gil, R.4    Cooper, T.B.5    Slifstein, M.6
  • 19
    • 67349207461 scopus 로고    scopus 로고
    • Baseline and amphetamine-stimulated dopamine activity are related in drug-naïve schizophrenic subjects
    • 19 Abi-Dargham, A., van de Giessen, E., Slifstein, M., Kegeles, L.S., Laruelle, M., Baseline and amphetamine-stimulated dopamine activity are related in drug-naïve schizophrenic subjects. Biol Psychiatry 65 (2009), 1091–1093.
    • (2009) Biol Psychiatry , vol.65 , pp. 1091-1093
    • Abi-Dargham, A.1    van de Giessen, E.2    Slifstein, M.3    Kegeles, L.S.4    Laruelle, M.5
  • 20
    • 0026450196 scopus 로고
    • Mesoprefrontal cortical dopaminergic activity and prefrontal hypofunction in schizophrenia
    • 20 Weinberger, D.R., Berman, K.F., Daniel, D.G., Mesoprefrontal cortical dopaminergic activity and prefrontal hypofunction in schizophrenia. Clin Neuropharmacol 15:suppl 1 (1992), 568A–569A.
    • (1992) Clin Neuropharmacol , vol.15 , pp. 568A-569A
    • Weinberger, D.R.1    Berman, K.F.2    Daniel, D.G.3
  • 21
    • 84925401870 scopus 로고    scopus 로고
    • Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia: A positron emission tomographic functional magnetic resonance imaging study
    • 21 Slifstein, M., van de Giessen, E., Van Snellenberg, J., Thompson, J.L., Narendran, R., Gil, R., et al. Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia: A positron emission tomographic functional magnetic resonance imaging study. JAMA Psychiatry 72 (2015), 316–324.
    • (2015) JAMA Psychiatry , vol.72 , pp. 316-324
    • Slifstein, M.1    van de Giessen, E.2    Van Snellenberg, J.3    Thompson, J.L.4    Narendran, R.5    Gil, R.6
  • 22
    • 84901857589 scopus 로고    scopus 로고
    • Alterations in cortical and extrastriatal subcortical dopamine function in schizophrenia: Systematic review and meta-analysis of imaging studies
    • 22 Kambeitz, J., Abi-Dargham, A., Kapur, S., Howes, O.D., Alterations in cortical and extrastriatal subcortical dopamine function in schizophrenia: Systematic review and meta-analysis of imaging studies. Br J Psychiatry 204 (2014), 420–429.
    • (2014) Br J Psychiatry , vol.204 , pp. 420-429
    • Kambeitz, J.1    Abi-Dargham, A.2    Kapur, S.3    Howes, O.D.4
  • 24
    • 85047695195 scopus 로고    scopus 로고
    • Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis
    • 24 McGlashan, T.H., Zipursky, R.B., Perkins, D., Addington, J., Miller, T., Woods, S.W., et al. Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. Am J Psychiatry 163 (2006), 790–799.
    • (2006) Am J Psychiatry , vol.163 , pp. 790-799
    • McGlashan, T.H.1    Zipursky, R.B.2    Perkins, D.3    Addington, J.4    Miller, T.5    Woods, S.W.6
  • 25
    • 37249022268 scopus 로고    scopus 로고
    • Acute effects of treatment for prodromal symptoms for people putatively in a late initial prodromal state of psychosis
    • 25 Ruhrmann, S., Bechdolf, A., Kühn, K.U., Wagner, M., Schultze-Lutter, F., Janssen, B., et al. Acute effects of treatment for prodromal symptoms for people putatively in a late initial prodromal state of psychosis. Br J Psychiatry Suppl 51 (2007), s88–s96.
    • (2007) Br J Psychiatry Suppl , vol.51 , pp. s88-s96
    • Ruhrmann, S.1    Bechdolf, A.2    Kühn, K.U.3    Wagner, M.4    Schultze-Lutter, F.5    Janssen, B.6
  • 27
    • 84874335378 scopus 로고    scopus 로고
    • Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive task
    • 27 Suridjan, I., Rusjan, P., Addington, J., Wilson, A.A., Houle, S., Mizrahi, R., Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive task. J Psychiatry Neurosci 38 (2013), 98–106.
    • (2013) J Psychiatry Neurosci , vol.38 , pp. 98-106
    • Suridjan, I.1    Rusjan, P.2    Addington, J.3    Wilson, A.A.4    Houle, S.5    Mizrahi, R.6
  • 29
    • 84873526852 scopus 로고    scopus 로고
    • Striatal dopamine D2/3 receptor binding following dopamine depletion in subjects at ultra high risk for psychosis
    • 29 Bloemen, O.J., de Koning, M.B., Gleich, T., Meijer, J., de Haan, L., Linszen, D.H., et al. Striatal dopamine D2/3 receptor binding following dopamine depletion in subjects at ultra high risk for psychosis. Eur Neuropsychopharmacol 23 (2013), 126–132.
    • (2013) Eur Neuropsychopharmacol , vol.23 , pp. 126-132
    • Bloemen, O.J.1    de Koning, M.B.2    Gleich, T.3    Meijer, J.4    de Haan, L.5    Linszen, D.H.6
  • 31
    • 84879507260 scopus 로고    scopus 로고
    • Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: Findings in a second cohort
    • 31 Egerton, A., Chaddock, C.A., Winton-Brown, T.T., Bloomfield, M.A., Bhattacharyya, S., Allen, P., et al. Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: Findings in a second cohort. Biol Psychiatry 74 (2013), 106–112.
    • (2013) Biol Psychiatry , vol.74 , pp. 106-112
    • Egerton, A.1    Chaddock, C.A.2    Winton-Brown, T.T.3    Bloomfield, M.A.4    Bhattacharyya, S.5    Allen, P.6
  • 32
    • 84857099124 scopus 로고    scopus 로고
    • Dopamine synthesis capacity before onset of psychosis: A prospective [18F]-DOPA PET imaging study
    • 32 Howes, O.D., Bose, S.K., Turkheimer, F., Valli, I., Egerton, A., Valmaggia, L.R., et al. Dopamine synthesis capacity before onset of psychosis: A prospective [18F]-DOPA PET imaging study. Am J Psychiatry 168 (2011), 1311–1317.
    • (2011) Am J Psychiatry , vol.168 , pp. 1311-1317
    • Howes, O.D.1    Bose, S.K.2    Turkheimer, F.3    Valli, I.4    Egerton, A.5    Valmaggia, L.R.6
  • 33
    • 80052068381 scopus 로고    scopus 로고
    • Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis : A PET study
    • 33 Howes, O., Bose, S., Turkheimer, F., Valli, I., Egerton, A., Stahl, D., et al. Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis : A PET study. Mol Psychiatry 16 (2011), 885–886.
    • (2011) Mol Psychiatry , vol.16 , pp. 885-886
    • Howes, O.1    Bose, S.2    Turkheimer, F.3    Valli, I.4    Egerton, A.5    Stahl, D.6
  • 34
    • 84866672831 scopus 로고    scopus 로고
    • Abnormal relationship between medial temporal lobe and subcortical dopamine function in people with an ultra high risk for psychosis
    • 34 Allen, P., Chaddock, C.A., Howes, O.D., Egerton, A., Seal, M.L., Fusar-Poli, P., et al. Abnormal relationship between medial temporal lobe and subcortical dopamine function in people with an ultra high risk for psychosis. Schizophr Bull 38 (2012), 1040–1049.
    • (2012) Schizophr Bull , vol.38 , pp. 1040-1049
    • Allen, P.1    Chaddock, C.A.2    Howes, O.D.3    Egerton, A.4    Seal, M.L.5    Fusar-Poli, P.6
  • 35
    • 78650512465 scopus 로고    scopus 로고
    • Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis
    • 35 Fusar-Poli, P., Howes, O.D., Allen, P., Broome, M., Valli, I., Asselin, M.-C., et al. Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis. Mol Psychiatry 16 (2011), 67–75.
    • (2011) Mol Psychiatry , vol.16 , pp. 67-75
    • Fusar-Poli, P.1    Howes, O.D.2    Allen, P.3    Broome, M.4    Valli, I.5    Asselin, M.-C.6
  • 36
    • 0036303358 scopus 로고    scopus 로고
    • Obstetric complications and schizophrenia : Historical and meta-analytic review
    • 36 Cannon, M., Ph, D., Jones, P.B., Murray, R.M., Obstetric complications and schizophrenia : Historical and meta-analytic review. Am J Psychiatry 159 (2002), 1080–1092.
    • (2002) Am J Psychiatry , vol.159 , pp. 1080-1092
    • Cannon, M.1    Ph, D.2    Jones, P.B.3    Murray, R.M.4
  • 37
    • 84923298138 scopus 로고    scopus 로고
    • Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: A case-control study
    • 37 Di Forti, M., Marconi, A., Carra, E., Fraietta, S., Trotta, A., Bonomo, M., et al. Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: A case-control study. Lancet Psychiatry 2 (2015), 233–238.
    • (2015) Lancet Psychiatry , vol.2 , pp. 233-238
    • Di Forti, M.1    Marconi, A.2    Carra, E.3    Fraietta, S.4    Trotta, A.5    Bonomo, M.6
  • 38
    • 84861647648 scopus 로고    scopus 로고
    • Childhood adversities increase the risk of psychosis: A meta-analysis of patient-control, prospective- and cross-sectional cohort studies
    • 38 Varese, F., Smeets, F., Drukker, M., Lieverse, R., Lataster, T., Viechtbauer, W., et al. Childhood adversities increase the risk of psychosis: A meta-analysis of patient-control, prospective- and cross-sectional cohort studies. Schizophr Bull 38 (2012), 661–671.
    • (2012) Schizophr Bull , vol.38 , pp. 661-671
    • Varese, F.1    Smeets, F.2    Drukker, M.3    Lieverse, R.4    Lataster, T.5    Viechtbauer, W.6
  • 39
    • 11844301246 scopus 로고    scopus 로고
    • Schizophrenia and migration : A meta-analysis and review
    • 39 Cantor-Graae, E., Selten, J., Schizophrenia and migration : A meta-analysis and review. Am J Psychiatry 162 (2005), 12–24.
    • (2005) Am J Psychiatry , vol.162 , pp. 12-24
    • Cantor-Graae, E.1    Selten, J.2
  • 40
    • 4243057297 scopus 로고    scopus 로고
    • A systematic review of the incidence of schizophrenia: The distribution of rates and the influence of sex, urbanicity, migrant status and methodology
    • 40 McGrath, J., Saha, S., Welham, J., El Saadi, O., MacCauley, C., Chant, D., A systematic review of the incidence of schizophrenia: The distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med, 2, 2004, 13.
    • (2004) BMC Med , vol.2 , pp. 13
    • McGrath, J.1    Saha, S.2    Welham, J.3    El Saadi, O.4    MacCauley, C.5    Chant, D.6
  • 41
    • 0023357150 scopus 로고
    • Stressful life events preceding the acute onset of schizophrenia: A cross-national study from the World Health Organization
    • 41 Day, R., Nielsen, J.A., Korten, A., Ernberg, G., Dube, K.C., Gebhart, J., et al. Stressful life events preceding the acute onset of schizophrenia: A cross-national study from the World Health Organization. Cult Med Psychiatry 11 (1987), 123–205.
    • (1987) Cult Med Psychiatry , vol.11 , pp. 123-205
    • Day, R.1    Nielsen, J.A.2    Korten, A.3    Ernberg, G.4    Dube, K.C.5    Gebhart, J.6
  • 42
    • 84859818593 scopus 로고    scopus 로고
    • Adversity and psychosis: A 10-year prospective study investigating synergism between early and recent adversity in psychosis
    • 42 Lataster, J., Myin-Germeys, I., Lieb, R., Wittchen, H.U., van Os, J., Adversity and psychosis: A 10-year prospective study investigating synergism between early and recent adversity in psychosis. Acta Psychiatr Scand 125 (2012), 388–399.
    • (2012) Acta Psychiatr Scand , vol.125 , pp. 388-399
    • Lataster, J.1    Myin-Germeys, I.2    Lieb, R.3    Wittchen, H.U.4    van Os, J.5
  • 43
    • 84966339609 scopus 로고    scopus 로고
    • Stress sensitivity, aberrant salience, and threat anticipation in early psychosis: An experience sampling study
    • 43 Reininghaus, U., Kempton, M.J., Valmaggia, L., Craig, T.K.J., Garety, P., Onyejiaka, A., et al. Stress sensitivity, aberrant salience, and threat anticipation in early psychosis: An experience sampling study. Schizophr Bull 42 (2016), 702–722.
    • (2016) Schizophr Bull , vol.42 , pp. 702-722
    • Reininghaus, U.1    Kempton, M.J.2    Valmaggia, L.3    Craig, T.K.J.4    Garety, P.5    Onyejiaka, A.6
  • 44
    • 0019190758 scopus 로고
    • Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in rats
    • 44 Pycock, C.J., Kerwin, R.W., Carter, C.J., Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in rats. Nature 286 (1980), 74–76.
    • (1980) Nature , vol.286 , pp. 74-76
    • Pycock, C.J.1    Kerwin, R.W.2    Carter, C.J.3
  • 45
    • 0033966893 scopus 로고    scopus 로고
    • The role of stress in the pathophysiology of the dopaminergic system
    • 45 Pani, L., Porcella, A., Gessa, G.L., The role of stress in the pathophysiology of the dopaminergic system. Mol Psychiatry 5 (2000), 14–21.
    • (2000) Mol Psychiatry , vol.5 , pp. 14-21
    • Pani, L.1    Porcella, A.2    Gessa, G.L.3
  • 46
    • 44649139791 scopus 로고    scopus 로고
    • Prefrontal cortex-nucleus accumbens interaction: In vivo modulation by dopamine and glutamate in the prefrontal cortex
    • 46 Del Arco, A., Mora, F., Prefrontal cortex-nucleus accumbens interaction: In vivo modulation by dopamine and glutamate in the prefrontal cortex. Pharmacol Biochem Behav 90 (2008), 226–235.
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 226-235
    • Del Arco, A.1    Mora, F.2
  • 47
    • 0028106177 scopus 로고
    • Stress-induced sensitization of dopamine and norepinephrine efflux in medial prefrontal cortex of the rat
    • 47 Gresch, P.J., Sved, A.F., Zigmond, M.J., Finlay, J.M., Stress-induced sensitization of dopamine and norepinephrine efflux in medial prefrontal cortex of the rat. J Neurochem 63 (1994), 575–583.
    • (1994) J Neurochem , vol.63 , pp. 575-583
    • Gresch, P.J.1    Sved, A.F.2    Zigmond, M.J.3    Finlay, J.M.4
  • 48
    • 0034652088 scopus 로고    scopus 로고
    • Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction
    • 48 Mizoguchi, K., Yuzurihara, M., Ishige, A., Sasaki, H., Chui, D.H., Tabira, T., Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. J Neurosci 20 (2000), 1568–1574.
    • (2000) J Neurosci , vol.20 , pp. 1568-1574
    • Mizoguchi, K.1    Yuzurihara, M.2    Ishige, A.3    Sasaki, H.4    Chui, D.H.5    Tabira, T.6
  • 49
    • 0027403696 scopus 로고
    • Repeated stressful experiences differently affect the time-dependent responses of the mesolimbic dopamine system to the stressor
    • 49 Imperato, A., Cabib, S., Puglisi-Alleggra, S., Repeated stressful experiences differently affect the time-dependent responses of the mesolimbic dopamine system to the stressor. Brain Res 601 (1993), 333–336.
    • (1993) Brain Res , vol.601 , pp. 333-336
    • Imperato, A.1    Cabib, S.2    Puglisi-Alleggra, S.3
  • 50
    • 0028216219 scopus 로고
    • Opposite responses of mesolimbic dopamine system to controllable and uncontrollable aversive experiences
    • 50 Cabib, S., Puglisi-Allegra, S., Opposite responses of mesolimbic dopamine system to controllable and uncontrollable aversive experiences. J Neurosci 14 (1994), 3333–3340.
    • (1994) J Neurosci , vol.14 , pp. 3333-3340
    • Cabib, S.1    Puglisi-Allegra, S.2
  • 51
    • 0029902505 scopus 로고    scopus 로고
    • Stress, depression and the mesolimbic dopamine system
    • 51 Cabib, S., Puglisi-Allegra, S., Stress, depression and the mesolimbic dopamine system. Psychopharmacology (Berl) 128 (1996), 331–342.
    • (1996) Psychopharmacology (Berl) , vol.128 , pp. 331-342
    • Cabib, S.1    Puglisi-Allegra, S.2
  • 52
    • 0018874396 scopus 로고
    • Interchangeability of stress and amphetamine in sensitization
    • 52 Antelman, S.M., Eichler, A.J., Black, C.A., Kocan, D., Interchangeability of stress and amphetamine in sensitization. Science 207 (1980), 329–331.
    • (1980) Science , vol.207 , pp. 329-331
    • Antelman, S.M.1    Eichler, A.J.2    Black, C.A.3    Kocan, D.4
  • 53
    • 0036299142 scopus 로고    scopus 로고
    • A single exposure to restraint stress induces behavioral and neurochemical sensitization to stimulating effects of amphetamine: Involvement of NMDA receptors
    • 53 Pacchioni, A.M., Gioino, G., Assis, A., Cancela, L.M., A single exposure to restraint stress induces behavioral and neurochemical sensitization to stimulating effects of amphetamine: Involvement of NMDA receptors. Ann N Y Acad Sci 965 (2002), 233–246.
    • (2002) Ann N Y Acad Sci , vol.965 , pp. 233-246
    • Pacchioni, A.M.1    Gioino, G.2    Assis, A.3    Cancela, L.M.4
  • 54
    • 84859958848 scopus 로고    scopus 로고
    • Different stressors produce excitation or inhibition of mesolimbic dopamine neuron activity: Response alteration by stress pre-exposure
    • 54 Valenti, O., Gill, K.M., Grace, A.A., Different stressors produce excitation or inhibition of mesolimbic dopamine neuron activity: Response alteration by stress pre-exposure. Eur J Neurosci 35 (2012), 1312–1321.
    • (2012) Eur J Neurosci , vol.35 , pp. 1312-1321
    • Valenti, O.1    Gill, K.M.2    Grace, A.A.3
  • 55
    • 40149083573 scopus 로고    scopus 로고
    • Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizophrenia, their unaffected siblings and controls
    • 55 Brunelin, J., d'Amato, T., van Os, J., Cochet, A., Suaud-Chagny, M.F., Saoud, M., Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizophrenia, their unaffected siblings and controls. Schizophr Res 100 (2008), 206–211.
    • (2008) Schizophr Res , vol.100 , pp. 206-211
    • Brunelin, J.1    d'Amato, T.2    van Os, J.3    Cochet, A.4    Suaud-Chagny, M.F.5    Saoud, M.6
  • 56
    • 22444444972 scopus 로고    scopus 로고
    • Subtle fluctuations in psychotic phenomena as functional states of abnormal dopamine reactivity in individuals at risk
    • 56 Myin-Germeys, I., Marcelis, M., Krabbendam, L., Delespaul, P., Van Os, J., Subtle fluctuations in psychotic phenomena as functional states of abnormal dopamine reactivity in individuals at risk. Biol Psychiatry 58 (2005), 105–110.
    • (2005) Biol Psychiatry , vol.58 , pp. 105-110
    • Myin-Germeys, I.1    Marcelis, M.2    Krabbendam, L.3    Delespaul, P.4    Van Os, J.5
  • 57
    • 80052620723 scopus 로고    scopus 로고
    • Psychosocial stress is associated with in vivo dopamine release in human ventromedial prefrontal cortex: A positron emission tomography study using [18F]fallypride
    • 57 Lataster, J., Collip, D., Ceccarini, J., Haas, D., Booij, L., van Os, J., et al. Psychosocial stress is associated with in vivo dopamine release in human ventromedial prefrontal cortex: A positron emission tomography study using [18F]fallypride. Neuroimage 58 (2011), 1081–1089.
    • (2011) Neuroimage , vol.58 , pp. 1081-1089
    • Lataster, J.1    Collip, D.2    Ceccarini, J.3    Haas, D.4    Booij, L.5    van Os, J.6
  • 58
    • 84885862017 scopus 로고    scopus 로고
    • Stress-induced dopamine release in human medial prefrontal cortex–18F-fallypride/PET study in healthy volunteers
    • 58 Nagano-Saito, A., Dagher, A., Booij, L., Gravel, P., Welfeld, K., Casey, K.F., et al. Stress-induced dopamine release in human medial prefrontal cortex–18F-fallypride/PET study in healthy volunteers. Synapse 67 (2013), 821–830.
    • (2013) Synapse , vol.67 , pp. 821-830
    • Nagano-Saito, A.1    Dagher, A.2    Booij, L.3    Gravel, P.4    Welfeld, K.5    Casey, K.F.6
  • 59
    • 84962128089 scopus 로고    scopus 로고
    • Early-life stress affects stress-related prefrontal dopamine activity in healthy adults, but not in individuals with psychotic disorder
    • 59 Kasanova, Z., Hernaus, D., Vaessen, T., van Amelsvoort, T., Winz, O., Heinzel, A., et al. Early-life stress affects stress-related prefrontal dopamine activity in healthy adults, but not in individuals with psychotic disorder. PLoS One, 11, 2016, e0150746.
    • (2016) PLoS One , vol.11 , pp. e0150746
    • Kasanova, Z.1    Hernaus, D.2    Vaessen, T.3    van Amelsvoort, T.4    Winz, O.5    Heinzel, A.6
  • 60
    • 84892658099 scopus 로고    scopus 로고
    • Familial liability to psychosis is associated with attenuated dopamine stress signaling in ventromedial prefrontal cortex
    • 60 Lataster, J., Collip, D., Ceccarini, J., Hernaus, D., Haas, D., Booij, L., et al. Familial liability to psychosis is associated with attenuated dopamine stress signaling in ventromedial prefrontal cortex. Schizophr Bull 40 (2014), 66–77.
    • (2014) Schizophr Bull , vol.40 , pp. 66-77
    • Lataster, J.1    Collip, D.2    Ceccarini, J.3    Hernaus, D.4    Haas, D.5    Booij, L.6
  • 61
    • 84925688203 scopus 로고    scopus 로고
    • Psychotic reactivity to daily life stress and the dopamine system : A study combining experience sampling and [18F]fallypride positron emission tomography
    • 61 Hernaus, D., Collip, D., Lataster, J., Viechtbauer, W., Myin, E., Ceccarini, J., Van Laere, K., van Os, J., Myin-Germeys, I., Psychotic reactivity to daily life stress and the dopamine system : A study combining experience sampling and [18F]fallypride positron emission tomography. J Abnorm Psychol 124 (2015), 27–37.
    • (2015) J Abnorm Psychol , vol.124 , pp. 27-37
    • Hernaus, D.1    Collip, D.2    Lataster, J.3    Viechtbauer, W.4    Myin, E.5    Ceccarini, J.6    Van Laere, K.7    van Os, J.8    Myin-Germeys, I.9
  • 62
    • 84990989642 scopus 로고    scopus 로고
    • No evidence for attenuated stress-induced extrastriatal dopamine signaling in psychotic disorder
    • 62 Hernaus, D., Collip, D., Kasanova, Z., Winz, O., Heinzel, A., van Amelsvoort, T., et al. No evidence for attenuated stress-induced extrastriatal dopamine signaling in psychotic disorder. Transl Psychiatry, 5, 2015, e547.
    • (2015) Transl Psychiatry , vol.5 , pp. e547
    • Hernaus, D.1    Collip, D.2    Kasanova, Z.3    Winz, O.4    Heinzel, A.5    van Amelsvoort, T.6
  • 64
    • 84995544906 scopus 로고    scopus 로고
    • Adversity in childhood linked to elevated striatal dopamine function in adulthood
    • 64 Egerton, A., Valmaggia, L.R., Howes, O.D., Day, F., Chaddock, C.A., Allen, P., et al. Adversity in childhood linked to elevated striatal dopamine function in adulthood. Schizophr Res 176 (2016), 171–176.
    • (2016) Schizophr Res , vol.176 , pp. 171-176
    • Egerton, A.1    Valmaggia, L.R.2    Howes, O.D.3    Day, F.4    Chaddock, C.A.5    Allen, P.6
  • 65
    • 1642315257 scopus 로고    scopus 로고
    • Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: A positron emission tomography study using [11C]raclopride
    • 65 Pruessner, J.C., Champagne, F., Meaney, M.J., Dagher, A., Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: A positron emission tomography study using [11C]raclopride. J Neurosci 24 (2004), 2825–2831.
    • (2004) J Neurosci , vol.24 , pp. 2825-2831
    • Pruessner, J.C.1    Champagne, F.2    Meaney, M.J.3    Dagher, A.4
  • 66
    • 84902152098 scopus 로고    scopus 로고
    • History of childhood adversity is positively associated with ventral striatal dopamine responses to amphetamine
    • 66 Oswald, L.M., Wand, G.S., Kuwabara, H., Wong, D.F., Zhu, S., Brasic, J.R., History of childhood adversity is positively associated with ventral striatal dopamine responses to amphetamine. Psychopharmacology (Berl) 231 (2014), 2417–2433.
    • (2014) Psychopharmacology (Berl) , vol.231 , pp. 2417-2433
    • Oswald, L.M.1    Wand, G.S.2    Kuwabara, H.3    Wong, D.F.4    Zhu, S.5    Brasic, J.R.6
  • 67
    • 84915748817 scopus 로고    scopus 로고
    • Increased release of dopamine in the striata of young adults with hearing impairment and its relevance for the social defeat hypothesis of schizophrenia
    • 67 Gevonden, M., Booij, J., van den Brink, W., Heijtel, D., van Os, J., Selten, J.-P., Increased release of dopamine in the striata of young adults with hearing impairment and its relevance for the social defeat hypothesis of schizophrenia. JAMA Psychiatry 71 (2014), 1364–1372.
    • (2014) JAMA Psychiatry , vol.71 , pp. 1364-1372
    • Gevonden, M.1    Booij, J.2    van den Brink, W.3    Heijtel, D.4    van Os, J.5    Selten, J.-P.6
  • 68
    • 0031255540 scopus 로고    scopus 로고
    • Schizophrenia: A neural diathesis-stress model
    • 68 Walker, E.F., Diforio, D., Schizophrenia: A neural diathesis-stress model. Psychol Rev 104 (1997), 667–685.
    • (1997) Psychol Rev , vol.104 , pp. 667-685
    • Walker, E.F.1    Diforio, D.2
  • 69
    • 16344365442 scopus 로고    scopus 로고
    • Developmental pathology, dopamine, and stress: A model for the age of onset of schizophrenia symptoms
    • 69 Thompson, J.L., Pogue-Geile, M.F., Grace, A.A., Developmental pathology, dopamine, and stress: A model for the age of onset of schizophrenia symptoms. Schizophr Bull 30 (2004), 875–900.
    • (2004) Schizophr Bull , vol.30 , pp. 875-900
    • Thompson, J.L.1    Pogue-Geile, M.F.2    Grace, A.A.3
  • 70
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • 70 Ripke, S., Neale, B.M., Corvin, A., Walters, J.T., Farh, K.H., Holmans, P.A., et al. Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511(7510), 2014, 421.
    • (2014) Nature , vol.511 , Issue.7510 , pp. 421
    • Ripke, S.1    Neale, B.M.2    Corvin, A.3    Walters, J.T.4    Farh, K.H.5    Holmans, P.A.6
  • 72
    • 84995609173 scopus 로고    scopus 로고
    • Evaluating the dopamine hypothesis of schizophrenia in a large-scale genome-wide association study
    • 72 Edwards, A.C., Bacanu, S., Bigdeli, T.B., Moscati, A., Kendler, K.S., Evaluating the dopamine hypothesis of schizophrenia in a large-scale genome-wide association study. Schizophr Res 176 (2016), 136–140.
    • (2016) Schizophr Res , vol.176 , pp. 136-140
    • Edwards, A.C.1    Bacanu, S.2    Bigdeli, T.B.3    Moscati, A.4    Kendler, K.S.5
  • 73
    • 0842310838 scopus 로고    scopus 로고
    • Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia
    • 73 Emamian, E.S., Hall, D., Birnbaum, M.J., Karayiorgou, M., Gogos, J.A., Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat Genet 36 (2004), 131–137.
    • (2004) Nat Genet , vol.36 , pp. 131-137
    • Emamian, E.S.1    Hall, D.2    Birnbaum, M.J.3    Karayiorgou, M.4    Gogos, J.A.5
  • 74
    • 84859348838 scopus 로고    scopus 로고
    • AKT/GSK3 signaling pathway and schizophrenia
    • 74 Emamian, E.S., AKT/GSK3 signaling pathway and schizophrenia. Front Mol Neurosci, 5, 2012, 33.
    • (2012) Front Mol Neurosci , vol.5 , pp. 33
    • Emamian, E.S.1
  • 75
    • 79952032110 scopus 로고    scopus 로고
    • The physiology, signaling, and pharmacology of dopamine receptors
    • 75 Beaulieu, J.-M., Gainetdinov, R.R., The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev 63 (2011), 182–217.
    • (2011) Pharmacol Rev , vol.63 , pp. 182-217
    • Beaulieu, J.-M.1    Gainetdinov, R.R.2
  • 76
    • 54249166128 scopus 로고    scopus 로고
    • Gene-environment interactions in schizophrenia: Review of epidemiological findings and future directions
    • 76 van Os, J., Rutten, B.P., Poulton, R., Gene-environment interactions in schizophrenia: Review of epidemiological findings and future directions. Schizophr Bull 34 (2008), 1066–1082.
    • (2008) Schizophr Bull , vol.34 , pp. 1066-1082
    • van Os, J.1    Rutten, B.P.2    Poulton, R.3
  • 77
    • 9744272427 scopus 로고    scopus 로고
    • Confirmation of synergy between urbanicity and familial liability in the causation of psychosis
    • 77 van Os, J., Pedersen, C.B., Mortensen, P.B., Confirmation of synergy between urbanicity and familial liability in the causation of psychosis. Am J Psychiatry 161 (2004), 2312–2314.
    • (2004) Am J Psychiatry , vol.161 , pp. 2312-2314
    • van Os, J.1    Pedersen, C.B.2    Mortensen, P.B.3
  • 78
    • 0029913969 scopus 로고    scopus 로고
    • Morbid risk of schizophrenia in first-degree relatives of white and African-Caribbean patients with psychosis
    • 78 Hutchinson, G., Takei, N., Fahy, T.A., Bhugra, D., Gilvarry, C., Moran, P., et al. Morbid risk of schizophrenia in first-degree relatives of white and African-Caribbean patients with psychosis. Br J Psychiatry 169 (1996), 776–780.
    • (1996) Br J Psychiatry , vol.169 , pp. 776-780
    • Hutchinson, G.1    Takei, N.2    Fahy, T.A.3    Bhugra, D.4    Gilvarry, C.5    Moran, P.6
  • 80
    • 36849013646 scopus 로고    scopus 로고
    • Striatal dopamine synthesis in first-degree relatives of patients with schizophrenia
    • 80 Huttunen, J., Heinimaa, M., Svirskis, T., Nyman, M., Kajander, J., Forsback, S., et al. Striatal dopamine synthesis in first-degree relatives of patients with schizophrenia. Biol Psychiatry 63 (2008), 114–177.
    • (2008) Biol Psychiatry , vol.63 , pp. 114-177
    • Huttunen, J.1    Heinimaa, M.2    Svirskis, T.3    Nyman, M.4    Kajander, J.5    Forsback, S.6
  • 82
    • 20144388474 scopus 로고    scopus 로고
    • Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia
    • 82 Hirvonen, J., van Erp, T.G.M., Huttunen, J., Aalto, S., Någren, K., Huttunen, M., et al. Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia. Arch Gen Psychiatry 62 (2005), 371–378.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 371-378
    • Hirvonen, J.1    van Erp, T.G.M.2    Huttunen, J.3    Aalto, S.4    Någren, K.5    Huttunen, M.6
  • 83
    • 48749114285 scopus 로고    scopus 로고
    • Loss of asymmetry in D2 receptors of putamen in unaffected family members at increased genetic risk for schizophrenia
    • 83 Lee, K.J., Lee, J.S., Kim, S.J., Correll, C.U., Wee, H., Yoo, S.Y., et al. Loss of asymmetry in D2 receptors of putamen in unaffected family members at increased genetic risk for schizophrenia. Acta Psychiatr Scand 118 (2008), 200–208.
    • (2008) Acta Psychiatr Scand , vol.118 , pp. 200-208
    • Lee, K.J.1    Lee, J.S.2    Kim, S.J.3    Correll, C.U.4    Wee, H.5    Yoo, S.Y.6
  • 84
    • 49649124127 scopus 로고    scopus 로고
    • Schizophrenia and 22q11.2 deletion syndrome
    • 84 Bassett, A.S., Chow, E.W.C., Schizophrenia and 22q11.2 deletion syndrome. Curr Psychiatry Rep 10 (2008), 148–157.
    • (2008) Curr Psychiatry Rep , vol.10 , pp. 148-157
    • Bassett, A.S.1    Chow, E.W.C.2
  • 86
    • 8444233260 scopus 로고    scopus 로고
    • The catechol-O-methyltransferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes
    • 86 Bilder, R.M., Volavka, J., Lachman, H.M., Grace, A.A., The catechol-O-methyltransferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology 29 (2004), 1943–1961.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1943-1961
    • Bilder, R.M.1    Volavka, J.2    Lachman, H.M.3    Grace, A.A.4
  • 87
    • 47749122607 scopus 로고    scopus 로고
    • COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET
    • 87 Slifstein, M., Kolachana, B., Simpson, E.H., Tabares, P., Cheng, B., Duvall, M., et al. COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET. Mol Psychiatry 13 (2008), 821–827.
    • (2008) Mol Psychiatry , vol.13 , pp. 821-827
    • Slifstein, M.1    Kolachana, B.2    Simpson, E.H.3    Tabares, P.4    Cheng, B.5    Duvall, M.6
  • 88
  • 89
    • 84879064248 scopus 로고    scopus 로고
    • COMT Val158Met genotype selectively alters prefrontal [18F]fallypride displacement and subjective feelings of stress in response to a psychosocial stress challenge
    • 89 Hernaus, D., Collip, D., Lataster, J., Ceccarini, J., Kenis, G., Booij, L., et al. COMT Val158Met genotype selectively alters prefrontal [18F]fallypride displacement and subjective feelings of stress in response to a psychosocial stress challenge. PLoS One, 8, 2013, e65662.
    • (2013) PLoS One , vol.8 , pp. e65662
    • Hernaus, D.1    Collip, D.2    Lataster, J.3    Ceccarini, J.4    Kenis, G.5    Booij, L.6
  • 90
    • 66249129704 scopus 로고    scopus 로고
    • Stress signalling pathways that impair prefrontal cortex structure and function
    • 90 Arnsten, A.F., Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci 10 (2010), 410–422.
    • (2010) Nat Rev Neurosci , vol.10 , pp. 410-422
    • Arnsten, A.F.1
  • 91
    • 84866333146 scopus 로고    scopus 로고
    • The COMT Val158Met polymorphism modulates working memory performance under acute stress
    • 91 Buckert, M., Kudielka, B.M., Reuter, M., Fiebach, C.J., The COMT Val158Met polymorphism modulates working memory performance under acute stress. Psychoneuroendocrinology 37 (2012), 1810–1821.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1810-1821
    • Buckert, M.1    Kudielka, B.M.2    Reuter, M.3    Fiebach, C.J.4
  • 92
    • 84864446489 scopus 로고    scopus 로고
    • The effect of moderate acute psychological stress on working memory-related neural activity is modulated by a genetic variation in catecholaminergic function in humans
    • 92 Qin, S., Cousijn, H., Rijpkema, M., Luo, J., Franke, B., Hermans, E.J., Fernández, G., The effect of moderate acute psychological stress on working memory-related neural activity is modulated by a genetic variation in catecholaminergic function in humans. Front Integr Neurosci, 6, 2012, 16.
    • (2012) Front Integr Neurosci , vol.6 , pp. 16
    • Qin, S.1    Cousijn, H.2    Rijpkema, M.3    Luo, J.4    Franke, B.5    Hermans, E.J.6    Fernández, G.7
  • 93
    • 84904561107 scopus 로고    scopus 로고
    • Additive gene-environment effects on hippocampal structure in healthy humans
    • 93 Rabl, U., Meyer, B.M., Diers, K., Bartova, L., Berger, A., Mandorfer, D., et al. Additive gene-environment effects on hippocampal structure in healthy humans. J Neurosci 34 (2014), 9917–9926.
    • (2014) J Neurosci , vol.34 , pp. 9917-9926
    • Rabl, U.1    Meyer, B.M.2    Diers, K.3    Bartova, L.4    Berger, A.5    Mandorfer, D.6
  • 94
    • 79955782889 scopus 로고    scopus 로고
    • Stress-related methylation of the catechol-O-methyltransferase Val158 allele predicts human prefrontal cognition and activity
    • 94 Ursini, G., Bollati, V., Fazio, L., Porcelli, A., Iacovelli, L., Catalani, A., et al. Stress-related methylation of the catechol-O-methyltransferase Val158 allele predicts human prefrontal cognition and activity. J Neurosci 31 (2011), 6692–6698.
    • (2011) J Neurosci , vol.31 , pp. 6692-6698
    • Ursini, G.1    Bollati, V.2    Fazio, L.3    Porcelli, A.4    Iacovelli, L.5    Catalani, A.6
  • 95
    • 84899478067 scopus 로고    scopus 로고
    • Valence-specific effects of BDNF Val66Met polymorphism on dopaminergic stress and reward processing in humans
    • 95 Pecina, M., Martinez-Jauand, M., Love, T., Heffernan, J., Montoya, P., Hodgkinson, C., et al. Valence-specific effects of BDNF Val66Met polymorphism on dopaminergic stress and reward processing in humans. J Neurosci 34 (2014), 5874–5881.
    • (2014) J Neurosci , vol.34 , pp. 5874-5881
    • Pecina, M.1    Martinez-Jauand, M.2    Love, T.3    Heffernan, J.4    Montoya, P.5    Hodgkinson, C.6
  • 97
    • 84875252257 scopus 로고    scopus 로고
    • DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience
    • 97 Peciña, M., Mickey, B.J., Love, T., Wang, H., Langenecker, S.A., Hodgkinson, C., et al. DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience. Cortex 49 (2013), 877–890.
    • (2013) Cortex , vol.49 , pp. 877-890
    • Peciña, M.1    Mickey, B.J.2    Love, T.3    Wang, H.4    Langenecker, S.A.5    Hodgkinson, C.6
  • 98
    • 84867617568 scopus 로고    scopus 로고
    • Early postnatal experience and DRD2 genotype affect dopamine receptor expression in the rat ventral striatum
    • 98 Lovic, V., Belay, H., Walker, C.-D., Burton, C.L., Meaney, M.J., Sokolowski, M., Fleming, A.S., Early postnatal experience and DRD2 genotype affect dopamine receptor expression in the rat ventral striatum. Behav Brain Res 237 (2013), 278–282.
    • (2013) Behav Brain Res , vol.237 , pp. 278-282
    • Lovic, V.1    Belay, H.2    Walker, C.-D.3    Burton, C.L.4    Meaney, M.J.5    Sokolowski, M.6    Fleming, A.S.7
  • 99
    • 39749200988 scopus 로고    scopus 로고
    • A network of dopaminergic gene variations implicated as risk factors for schizophrenia
    • 99 Talkowski, M.E., Kirov, G., Bamne, M., Georgieva, L., Torres, G., Mansour, H., et al. A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Hum Mol Genet 17 (2008), 747–758.
    • (2008) Hum Mol Genet , vol.17 , pp. 747-758
    • Talkowski, M.E.1    Kirov, G.2    Bamne, M.3    Georgieva, L.4    Torres, G.5    Mansour, H.6
  • 100
    • 24344508546 scopus 로고    scopus 로고
    • Mutation in the vesicular monoamine gene, SLC18A1, associated with schizophrenia
    • 100 Bly, M., Mutation in the vesicular monoamine gene, SLC18A1, associated with schizophrenia. Schizophr Res 78 (2005), 337–338.
    • (2005) Schizophr Res , vol.78 , pp. 337-338
    • Bly, M.1
  • 102
    • 33745221854 scopus 로고    scopus 로고
    • A review of disrupted-in-schizophrenia-1 (DISC1): Neurodevelopment, cognition, and mental conditions
    • 102 Ishizuka, K., Paek, M., Kamiya, A., Sawa, A., A review of disrupted-in-schizophrenia-1 (DISC1): Neurodevelopment, cognition, and mental conditions. Biol Psychiatry 59 (2006), 1189–1197.
    • (2006) Biol Psychiatry , vol.59 , pp. 1189-1197
    • Ishizuka, K.1    Paek, M.2    Kamiya, A.3    Sawa, A.4
  • 103
    • 79955884485 scopus 로고    scopus 로고
    • Modelling schizophrenia using human induced pluripotent stem cells
    • 103 Brennand, K.J., Simone, A., Jou, J., Gelboin-Burkhart, C., Tran, N., Sangar, S., et al. Modelling schizophrenia using human induced pluripotent stem cells. Nature 473 (2011), 221–225.
    • (2011) Nature , vol.473 , pp. 221-225
    • Brennand, K.J.1    Simone, A.2    Jou, J.3    Gelboin-Burkhart, C.4    Tran, N.5    Sangar, S.6
  • 105
    • 84872443390 scopus 로고    scopus 로고
    • Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids
    • 105 Niwa, M., Jaaro-Peled, H., Tankou, S., Seshadri, S., Hikida, T., Matsumoto, Y., et al. Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science339, 2013, 335–339.
    • (2013) Science339 , pp. 335-339
    • Niwa, M.1    Jaaro-Peled, H.2    Tankou, S.3    Seshadri, S.4    Hikida, T.5    Matsumoto, Y.6
  • 106
    • 27944502874 scopus 로고    scopus 로고
    • DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
    • 106 Millar, J.K., Pickard, B.S., Mackie, S., James, R., Christie, S., Buchanan, S.R., et al. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 310 (2005), 1187–1191.
    • (2005) Science , vol.310 , pp. 1187-1191
    • Millar, J.K.1    Pickard, B.S.2    Mackie, S.3    James, R.4    Christie, S.5    Buchanan, S.R.6
  • 108
    • 84890213480 scopus 로고    scopus 로고
    • Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction
    • 108 Gamo, N.J., Duque, A., Paspalas, C.D., Kata, A., Fine, R., Boven, L., et al. Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction. Transl Psychiatry, 3, 2013, e328.
    • (2013) Transl Psychiatry , vol.3 , pp. e328
    • Gamo, N.J.1    Duque, A.2    Paspalas, C.D.3    Kata, A.4    Fine, R.5    Boven, L.6
  • 109
    • 84920646061 scopus 로고    scopus 로고
    • Genetic risk for schizophrenia: Convergence on synaptic pathways involved in plasticity
    • 109 Hall, J., Trent, S., Thomas, K.L., O'Donovan, M.C., Owen, M.J., Genetic risk for schizophrenia: Convergence on synaptic pathways involved in plasticity. Biol Psychiatry 77 (2014), 52–58.
    • (2014) Biol Psychiatry , vol.77 , pp. 52-58
    • Hall, J.1    Trent, S.2    Thomas, K.L.3    O'Donovan, M.C.4    Owen, M.J.5
  • 110
    • 84922233431 scopus 로고    scopus 로고
    • Glutamate and dopamine in schizophrenia : An update for the 21st century
    • 110 Howes, O., McCutcheon, R., Stone, J., Glutamate and dopamine in schizophrenia : An update for the 21st century. J Psychopharmacol 29 (2015), 97–115.
    • (2015) J Psychopharmacol , vol.29 , pp. 97-115
    • Howes, O.1    McCutcheon, R.2    Stone, J.3
  • 111
    • 84875694512 scopus 로고    scopus 로고
    • Vulnerability to psychotogenic effects of ketamine is associated with elevated D2/3-receptor availability
    • 111 Vernaleken, I., Klomp, M., Moeller, O., Raptis, M., Nagels, A., Rösch, F., et al. Vulnerability to psychotogenic effects of ketamine is associated with elevated D2/3-receptor availability. Int J Neuropsychopharmacol 16 (2013), 745–754.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 745-754
    • Vernaleken, I.1    Klomp, M.2    Moeller, O.3    Raptis, M.4    Nagels, A.5    Rösch, F.6
  • 112
    • 2942537881 scopus 로고    scopus 로고
    • NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex
    • 112 Jackson, M.E., Homayoun, H., Moghaddam, B., NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Proc Natl Acad Sci U S A 101 (2004), 8467–8472.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8467-8472
    • Jackson, M.E.1    Homayoun, H.2    Moghaddam, B.3
  • 114
    • 84908030684 scopus 로고    scopus 로고
    • Human iPSC neurons display activity-dependent neurotransmitter secretion: Aberrant catecholamine levels in schizophrenia neurons
    • 114 Hook, V., Brennand, K.J., Kim, Y., Toneff, T., Funkelstein, L., Lee, K.C., et al. Human iPSC neurons display activity-dependent neurotransmitter secretion: Aberrant catecholamine levels in schizophrenia neurons. Stem Cell Reports 3 (2014), 531–538.
    • (2014) Stem Cell Reports , vol.3 , pp. 531-538
    • Hook, V.1    Brennand, K.J.2    Kim, Y.3    Toneff, T.4    Funkelstein, L.5    Lee, K.C.6
  • 115
    • 84155160658 scopus 로고    scopus 로고
    • The stressed synapse: The impact of stress and glucocorticoids on glutamate transmission
    • 115 Popoli, M., Yan, Z., McEwen, B.S., Sanacora, G., The stressed synapse: The impact of stress and glucocorticoids on glutamate transmission. Nat Rev Neurosci 13 (2012), 22–37.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 22-37
    • Popoli, M.1    Yan, Z.2    McEwen, B.S.3    Sanacora, G.4
  • 116
    • 84930520305 scopus 로고    scopus 로고
    • Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia
    • 116 Pocklington, A.J., Rees, E., Walters, J.T., Han, J., Kavanagh, D.H., Chambert, K.D., et al. Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia. Neuron 86 (2015), 1203–1214.
    • (2015) Neuron , vol.86 , pp. 1203-1214
    • Pocklington, A.J.1    Rees, E.2    Walters, J.T.3    Han, J.4    Kavanagh, D.H.5    Chambert, K.D.6
  • 117
    • 84870168817 scopus 로고    scopus 로고
    • Rolel of dopamine D(2) receptors for antipsychotic activity
    • 117 Ginovart, N., Kapur, S., Rolel of dopamine D(2) receptors for antipsychotic activity. Handb Exp Pharmacol 212 (2012), 27–52.
    • (2012) Handb Exp Pharmacol , vol.212 , pp. 27-52
    • Ginovart, N.1    Kapur, S.2
  • 118
    • 84868591380 scopus 로고    scopus 로고
    • Dopamine synthesis capacity in patients with treatment-resistant schizophrenia
    • 118 Demjaha, A., Murray, R.M., McGuire, P.K., Kapur, S., Howes, O.D., Dopamine synthesis capacity in patients with treatment-resistant schizophrenia. Am J Psychiatry 169 (2012), 1203–1210.
    • (2012) Am J Psychiatry , vol.169 , pp. 1203-1210
    • Demjaha, A.1    Murray, R.M.2    McGuire, P.K.3    Kapur, S.4    Howes, O.D.5
  • 119
    • 84862116186 scopus 로고    scopus 로고
    • Evidence-based pharmacotherapy of post-traumatic stress disorder (PTSD)
    • 119 Ipser, J.C., Stein, D.J., Evidence-based pharmacotherapy of post-traumatic stress disorder (PTSD). Int J Neuropsychopharmacol 15 (2012), 825–840.
    • (2012) Int J Neuropsychopharmacol , vol.15 , pp. 825-840
    • Ipser, J.C.1    Stein, D.J.2
  • 120
    • 84936945435 scopus 로고    scopus 로고
    • Meta-analysis of efficacy of mirtazapine as an adjunctive treatment of negative symptoms in schizophrenia
    • 120 Vidal, C., Reese, C., Fischer, B.A., Chiapelli, J., Himelhoch, S., Meta-analysis of efficacy of mirtazapine as an adjunctive treatment of negative symptoms in schizophrenia. Clin Schizophr Relat Psychoses 9 (2015), 88–95.
    • (2015) Clin Schizophr Relat Psychoses , vol.9 , pp. 88-95
    • Vidal, C.1    Reese, C.2    Fischer, B.A.3    Chiapelli, J.4    Himelhoch, S.5
  • 121
    • 84881176306 scopus 로고    scopus 로고
    • Striatal dopamine release in schizophrenia comorbid with substance dependence
    • 121 Thompson, J.L., Urban, N., Slifstein, M., Xu, X., Kegeles, L.S., Girgis, R.R., et al. Striatal dopamine release in schizophrenia comorbid with substance dependence. Mol Psychiatry 18 (2013), 909–915.
    • (2013) Mol Psychiatry , vol.18 , pp. 909-915
    • Thompson, J.L.1    Urban, N.2    Slifstein, M.3    Xu, X.4    Kegeles, L.S.5    Girgis, R.R.6
  • 122
    • 84894479797 scopus 로고    scopus 로고
    • Dopaminergic function in cannabis users and its relationship to cannabis-induced psychotic symptoms
    • 122 Bloomfield, M.A., Morgan, C.J., Egerton, A., Kapur, S., Curran, H.V., Howes, O.D., Dopaminergic function in cannabis users and its relationship to cannabis-induced psychotic symptoms. Biol Psychiatry 75 (2014), 470–478.
    • (2014) Biol Psychiatry , vol.75 , pp. 470-478
    • Bloomfield, M.A.1    Morgan, C.J.2    Egerton, A.3    Kapur, S.4    Curran, H.V.5    Howes, O.D.6
  • 125
    • 84906736005 scopus 로고    scopus 로고
    • Positive symptoms in first-episode psychosis patients experiencing low maternal care and stressful life events: A pilot study to explore the role of the COMT gene
    • 125 Ira, E., De Santi, K., Lasalvia, A., Bonetto, C., Zanatta, G., Cristofalo, D., et al. Positive symptoms in first-episode psychosis patients experiencing low maternal care and stressful life events: A pilot study to explore the role of the COMT gene. Stress 17 (2014), 410–415.
    • (2014) Stress , vol.17 , pp. 410-415
    • Ira, E.1    De Santi, K.2    Lasalvia, A.3    Bonetto, C.4    Zanatta, G.5    Cristofalo, D.6
  • 126
    • 34548185207 scopus 로고    scopus 로고
    • Clinical involvement of catechol-O-methyltransferase polymorphisms in schizophrenia spectrum disorders: Influence on the severity of psychotic symptoms and on the response to neuroleptic treatment
    • 126 Molero, P., Ortuño, F., Zalacain, M., Patiño-García, A., Clinical involvement of catechol-O-methyltransferase polymorphisms in schizophrenia spectrum disorders: Influence on the severity of psychotic symptoms and on the response to neuroleptic treatment. Pharmacogenomics J 7 (2007), 418–426.
    • (2007) Pharmacogenomics J , vol.7 , pp. 418-426
    • Molero, P.1    Ortuño, F.2    Zalacain, M.3    Patiño-García, A.4
  • 128
    • 37849038622 scopus 로고    scopus 로고
    • Evidence that the COMT(Val158Met) polymorphism moderates sensitivity to stress in psychosis: An experience-sampling study
    • 128 van Winkel, R., Henquet, C., Rosa, A., Papiol, S., Fananás, L., De Hert, M., et al. Evidence that the COMT(Val158Met) polymorphism moderates sensitivity to stress in psychosis: An experience-sampling study. Am J Med Genet Part B Neuropsychiatr Genet 147B (2008), 10–17.
    • (2008) Am J Med Genet Part B Neuropsychiatr Genet , vol.147B , pp. 10-17
    • van Winkel, R.1    Henquet, C.2    Rosa, A.3    Papiol, S.4    Fananás, L.5    De Hert, M.6
  • 129
    • 16344372645 scopus 로고    scopus 로고
    • Cortical inhibitory neurons and schizophrenia
    • 129 Lewis, D.A., Hashimoto, T., Volk, D.W., Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 6 (2005), 312–324.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 312-324
    • Lewis, D.A.1    Hashimoto, T.2    Volk, D.W.3
  • 130
  • 131
    • 77956934157 scopus 로고    scopus 로고
    • Altered relationship between hippocampal glutamate levels and striatal dopamine function in subjects at ultra high risk of psychosis
    • Elsevier Inc.599–602
    • 131 Stone, J.M., Howes, O.D., Egerton, A., Kambeitz, J., Allen, P., Lythgoe, D.J., et al. Altered relationship between hippocampal glutamate levels and striatal dopamine function in subjects at ultra high risk of psychosis. Biol Psychiatry, 68, 2010 Elsevier Inc.599–602.
    • (2010) Biol Psychiatry , vol.68
    • Stone, J.M.1    Howes, O.D.2    Egerton, A.3    Kambeitz, J.4    Allen, P.5    Lythgoe, D.J.6
  • 132
    • 2342471341 scopus 로고    scopus 로고
    • Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide
    • 132 Abi-Dargham, A., Kegeles, L.S., Zea-Ponce, Y., Mawlawi, O., Martinez, D., Mitropoulou, V., et al. Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide. Biol Psychiatry 55 (2004), 1001–1006.
    • (2004) Biol Psychiatry , vol.55 , pp. 1001-1006
    • Abi-Dargham, A.1    Kegeles, L.S.2    Zea-Ponce, Y.3    Mawlawi, O.4    Martinez, D.5    Mitropoulou, V.6
  • 134
    • 75449091144 scopus 로고    scopus 로고
    • Increased left striatal dopamine transmission in unaffected siblings of schizophrenia patients in response to acute metabolic stress
    • 134 Brunelin, J., d'Amato, T., Van Os, J., Costes, N., Suaud Chagny, M.-F., Saoud, M., Increased left striatal dopamine transmission in unaffected siblings of schizophrenia patients in response to acute metabolic stress. Psychiatry Res 181 (2010), 130–135.
    • (2010) Psychiatry Res , vol.181 , pp. 130-135
    • Brunelin, J.1    d'Amato, T.2    Van Os, J.3    Costes, N.4    Suaud Chagny, M.-F.5    Saoud, M.6
  • 135
    • 33144461109 scopus 로고    scopus 로고
    • Striatal dopamine D1 and D2 receptor balance in twins at increased genetic risk for schizophrenia
    • 135 Hirvonen, J., van Erp, T.G.M., Huttunen, J., Någren, K., Huttunen, M., Aalto, S., et al. Striatal dopamine D1 and D2 receptor balance in twins at increased genetic risk for schizophrenia. Psychiatry Res 146 (2006), 13–20.
    • (2006) Psychiatry Res , vol.146 , pp. 13-20
    • Hirvonen, J.1    van Erp, T.G.M.2    Huttunen, J.3    Någren, K.4    Huttunen, M.5    Aalto, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.