Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis

Molecular Psychiatry

Volumn 16, Issue 1, 2011, Pages 67-75

  Fusar Poli, P ^a   Howes, O D ^a,b   Allen, P ^a   Broome, M ^a   Valli, I ^a   Asselin, M C ^b   Montgomery, A J ^b   Grasby, P M ^b   McGuire, P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

At Risk Mental State; dopamine; fMRI; PET; prodromal psychosis; verbal fluency

Indexed keywords

DOPAMINE; FLUORO LEVODOPA F 18; RADIOISOTOPE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRAIN FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOPAMINERGIC SYSTEM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIGH RISK POPULATION; HUMAN; MALE; MENTAL HEALTH; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; PSYCHOSIS; STRIATE CORTEX;

ADULT; BRAIN MAPPING; CASE-CONTROL STUDIES; DOPAMINE; EARLY DIAGNOSIS; EXECUTIVE FUNCTION; HUMANS; MAGNETIC RESONANCE IMAGING; NEOSTRIATUM; POSITRON-EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRESYNAPTIC TERMINALS; REFERENCE VALUES; RISK FACTORS; SCHIZOPHRENIA; VERBAL BEHAVIOR;

EID: 78650512465     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2009.108     Document Type: Article

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