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Volumn 59, Issue 12, 2006, Pages 1189-1197

A Review of Disrupted-in-Schizophrenia-1 (disc1): Neurodevelopment, Cognition, and Mental Conditions

Author keywords

DISC1; knockout mice; neurodevelopment; schizophrenia; transgenic mice

Indexed keywords

CYCLIC AMP; DYNEIN ADENOSINE TRIPHOSPHATASE; ISOPROTEIN; MESSENGER RNA; TAMOXIFEN; TETRACYCLINE;

EID: 33745221854     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2006.03.065     Document Type: Review
Times cited : (170)

References (64)
  • 1
    • 0030827595 scopus 로고    scopus 로고
    • Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex
    • Anton E.S., Marchionni M.A., Lee K.F., and Rakic P. Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex. Development 124 (1997) 3501-3510
    • (1997) Development , vol.124 , pp. 3501-3510
    • Anton, E.S.1    Marchionni, M.A.2    Lee, K.F.3    Rakic, P.4
  • 2
    • 0442292274 scopus 로고    scopus 로고
    • Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development
    • Austin C.P., Ky B., Ma L., Morris J.A., and Shughrue P.J. Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development. Neuroscience 124 (2004) 3-10
    • (2004) Neuroscience , vol.124 , pp. 3-10
    • Austin, C.P.1    Ky, B.2    Ma, L.3    Morris, J.A.4    Shughrue, P.J.5
  • 3
    • 0037560038 scopus 로고    scopus 로고
    • DISC1 (Disrupted in Schizophrenia-1) is expressed in limbic regions of the primate brain
    • Austin C.P., Ma L., Ky B., Morris J.A., and Shughrue P.J. DISC1 (Disrupted in Schizophrenia-1) is expressed in limbic regions of the primate brain. Neuroreport 14 (2003) 951-954
    • (2003) Neuroreport , vol.14 , pp. 951-954
    • Austin, C.P.1    Ma, L.2    Ky, B.3    Morris, J.A.4    Shughrue, P.J.5
  • 4
    • 0344395644 scopus 로고    scopus 로고
    • RNAi reveals doublecortin is required for radial migration in rat neocortex
    • Bai J., Ramos R.L., Ackman J.B., Thomas A.M., Lee R.V., and LoTurco J.J. RNAi reveals doublecortin is required for radial migration in rat neocortex. Nat Neurosci 6 (2003) 1277-1283
    • (2003) Nat Neurosci , vol.6 , pp. 1277-1283
    • Bai, J.1    Ramos, R.L.2    Ackman, J.B.3    Thomas, A.M.4    Lee, R.V.5    LoTurco, J.J.6
  • 5
    • 0034927864 scopus 로고    scopus 로고
    • Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes. Clinical and P300 findings in a family
    • Blackwood D.H., Fordyce A., Walker M.T., St Clair D.M., Porteous D.J., and Muir W.J. Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes. Clinical and P300 findings in a family. Am J Hum Genet 69 (2001) 428-433
    • (2001) Am J Hum Genet , vol.69 , pp. 428-433
    • Blackwood, D.H.1    Fordyce, A.2    Walker, M.T.3    St Clair, D.M.4    Porteous, D.J.5    Muir, W.J.6
  • 6
    • 10744229990 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex. Implications for schizophrenia and other major neurological disorders
    • Brandon N.J., Handford E.J., Schurov I., Rain J.C., Pelling M., Duran-Jimeniz B., et al. Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex. Implications for schizophrenia and other major neurological disorders. Mol Cell Neurosci 25 (2004) 42-55
    • (2004) Mol Cell Neurosci , vol.25 , pp. 42-55
    • Brandon, N.J.1    Handford, E.J.2    Schurov, I.3    Rain, J.C.4    Pelling, M.5    Duran-Jimeniz, B.6
  • 10
    • 27744554247 scopus 로고    scopus 로고
    • Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory
    • Cannon T.D., Hennah W., van Erp T.G., Thompson P.M., Lonnqvist J., Huttunen M., et al. Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Arch Gen Psychiatry 62 (2005) 1205-1213
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1205-1213
    • Cannon, T.D.1    Hennah, W.2    van Erp, T.G.3    Thompson, P.M.4    Lonnqvist, J.5    Huttunen, M.6
  • 11
    • 12444256025 scopus 로고    scopus 로고
    • Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q
    • Curtis D., Kalsi G., Brynjolfsson J., McInnis M., O'Neill J., Smyth C., et al. Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q. Psychiatr Genet 13 (2003) 77-84
    • (2003) Psychiatr Genet , vol.13 , pp. 77-84
    • Curtis, D.1    Kalsi, G.2    Brynjolfsson, J.3    McInnis, M.4    O'Neill, J.5    Smyth, C.6
  • 12
    • 13044281675 scopus 로고    scopus 로고
    • A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2
    • Detera-Wadleigh S.D., Badner J.A., Berrettini W.H., Yoshikawa T., Goldin L.R., Turner G., et al. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci U S A 96 (1999) 5604-5609
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5604-5609
    • Detera-Wadleigh, S.D.1    Badner, J.A.2    Berrettini, W.H.3    Yoshikawa, T.4    Goldin, L.R.5    Turner, G.6
  • 13
    • 0034941967 scopus 로고    scopus 로고
    • Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder
    • Devon R.S., Anderson S., Teague P.W., Burgess P., Kipari T.M., Semple C.A., et al. Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder. Psychiatr Genet 11 (2001) 71-78
    • (2001) Psychiatr Genet , vol.11 , pp. 71-78
    • Devon, R.S.1    Anderson, S.2    Teague, P.W.3    Burgess, P.4    Kipari, T.M.5    Semple, C.A.6
  • 16
    • 25844501532 scopus 로고    scopus 로고
    • Genome wide linkage scan in schizoaffective disorder. Significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
    • Hamshere M., Bennett P., Williams N., Segurado R., Cardno A., Norton N., et al. Genome wide linkage scan in schizoaffective disorder. Significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Arch Gen Psychiatry 62 (2005) 1081-1088
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1081-1088
    • Hamshere, M.1    Bennett, P.2    Williams, N.3    Segurado, R.4    Cardno, A.5    Norton, N.6
  • 17
    • 20144374692 scopus 로고    scopus 로고
    • Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1
    • Hayashi M.A., Portaro F.C., Bastos M.F., Guerreiro J.R., Oliveira V., Gorrao S.S., et al. Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1. Proc Natl Acad Sci U S A 102 (2005) 3828-3833
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3828-3833
    • Hayashi, M.A.1    Portaro, F.C.2    Bastos, M.F.3    Guerreiro, J.R.4    Oliveira, V.5    Gorrao, S.S.6
  • 18
    • 32844455739 scopus 로고    scopus 로고
    • A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia
    • Hennah W., Tuulio-Henriksson A., Paunio T., Ekelund J., Varilo T., Partonen T., et al. A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia. Mol Psychiatry 10 (2005) 1097-1103
    • (2005) Mol Psychiatry , vol.10 , pp. 1097-1103
    • Hennah, W.1    Tuulio-Henriksson, A.2    Paunio, T.3    Ekelund, J.4    Varilo, T.5    Partonen, T.6
  • 19
    • 0345530985 scopus 로고    scopus 로고
    • Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects
    • Hennah W., Varilo T., Kestila M., Paunio T., Arajarvi R., Haukka J., et al. Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects. Hum Mol Genet 12 (2003) 3151-3159
    • (2003) Hum Mol Genet , vol.12 , pp. 3151-3159
    • Hennah, W.1    Varilo, T.2    Kestila, M.3    Paunio, T.4    Arajarvi, R.5    Haukka, J.6
  • 20
    • 6344255274 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 (DISC1). Association with schizophrenia, schizoaffective disorder, and bipolar disorder
    • Hodgkinson C.A., Goldman D., Jaeger J., Persaud S., Kane J.M., Lipsky R.H., et al. Disrupted in Schizophrenia 1 (DISC1). Association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am J Hum Genet 75 (2004) 862-872
    • (2004) Am J Hum Genet , vol.75 , pp. 862-872
    • Hodgkinson, C.A.1    Goldman, D.2    Jaeger, J.3    Persaud, S.4    Kane, J.M.5    Lipsky, R.H.6
  • 21
    • 0037953124 scopus 로고    scopus 로고
    • Linkage of schizophrenia with chromosome 1q loci in Taiwanese families
    • Hwu H.G., Liu C.M., Fann C.S., Ou-Yang W.C., and Lee S.F. Linkage of schizophrenia with chromosome 1q loci in Taiwanese families. Mol Psychiatry 8 (2003) 445-452
    • (2003) Mol Psychiatry , vol.8 , pp. 445-452
    • Hwu, H.G.1    Liu, C.M.2    Fann, C.S.3    Ou-Yang, W.C.4    Lee, S.F.5
  • 22
    • 2342539835 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria
    • James R., Adams R.R., Christie S., Buchanan S.R., Porteous D.J., and Millar J.K. Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria. Mol Cell Neurosci 26 (2004) 112-122
    • (2004) Mol Cell Neurosci , vol.26 , pp. 112-122
    • James, R.1    Adams, R.R.2    Christie, S.3    Buchanan, S.R.4    Porteous, D.J.5    Millar, J.K.6
  • 23
    • 28544453286 scopus 로고    scopus 로고
    • A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
    • Kamiya A., Kubo K., Tomoda T., Takaki M., Youn R., Ozeki Y., et al. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol 7 (2005) 1067-1078
    • (2005) Nat Cell Biol , vol.7 , pp. 1067-1078
    • Kamiya, A.1    Kubo, K.2    Tomoda, T.3    Takaki, M.4    Youn, R.5    Ozeki, Y.6
  • 24
    • 33745214802 scopus 로고    scopus 로고
    • Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, Roberts RC (in press): DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. J Comp Neurol
  • 25
    • 4444315059 scopus 로고    scopus 로고
    • Association study of polymorphisms in the 5' upstream region of human DISC1 gene with schizophrenia
    • Kockelkorn T.T., Arai M., Matsumoto H., Fukuda N., Yamada K., Minabe Y., et al. Association study of polymorphisms in the 5' upstream region of human DISC1 gene with schizophrenia. Neurosci Lett 368 (2004) 41-45
    • (2004) Neurosci Lett , vol.368 , pp. 41-45
    • Kockelkorn, T.T.1    Arai, M.2    Matsumoto, H.3    Fukuda, N.4    Yamada, K.5    Minabe, Y.6
  • 26
    • 33644871334 scopus 로고    scopus 로고
    • Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice
    • Koike H., Kvajo M., Karayiorgou M., and Gogos J.A. Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice. Proc Natl Acad Sci U S A 103 10 (2006) 3693-3697
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.10 , pp. 3693-3697
    • Koike, H.1    Kvajo, M.2    Karayiorgou, M.3    Gogos, J.A.4
  • 27
    • 16344372645 scopus 로고    scopus 로고
    • Cortical inhibitory neurons and schizophrenia
    • Lewis D.A., Hashimoto T., and Volk D.W. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 6 (2005) 312-324
    • (2005) Nat Rev Neurosci , vol.6 , pp. 312-324
    • Lewis, D.A.1    Hashimoto, T.2    Volk, D.W.3
  • 28
    • 0036308284 scopus 로고    scopus 로고
    • Schizophrenia as a disorder of neurodevelopment
    • Lewis D.A., and Levitt P. Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci 25 (2002) 409-432
    • (2002) Annu Rev Neurosci , vol.25 , pp. 409-432
    • Lewis, D.A.1    Levitt, P.2
  • 29
    • 0041854263 scopus 로고    scopus 로고
    • Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)
    • Li W., Zhang Q., Oiso N., Novak E.K., Gautam R., O'Brien E.P., et al. Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Nat Genet 35 (2003) 84-89
    • (2003) Nat Genet , vol.35 , pp. 84-89
    • Li, W.1    Zhang, Q.2    Oiso, N.3    Novak, E.K.4    Gautam, R.5    O'Brien, E.P.6
  • 31
    • 12244278574 scopus 로고    scopus 로고
    • Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1)
    • Ma L., Liu Y., Ky B., Shughrue P.J., Austin C.P., and Morris J.A. Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1). Genomics 80 (2002) 662-672
    • (2002) Genomics , vol.80 , pp. 662-672
    • Ma, L.1    Liu, Y.2    Ky, B.3    Shughrue, P.J.4    Austin, C.P.5    Morris, J.A.6
  • 32
    • 11244302487 scopus 로고    scopus 로고
    • A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42
    • Macgregor S., Visscher P.M., Knott S.A., Thomson P., Porteous D.J., Millar J.K., et al. A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42. Mol Psychiatry 9 (2004) 1083-1090
    • (2004) Mol Psychiatry , vol.9 , pp. 1083-1090
    • Macgregor, S.1    Visscher, P.M.2    Knott, S.A.3    Thomson, P.4    Porteous, D.J.5    Millar, J.K.6
  • 33
    • 0038614937 scopus 로고    scopus 로고
    • Genome-wide scan of bipolar disorder in 65 pedigrees. Supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12
    • McInnis M.G., Lan T.H., Willour V.L., McMahon F.J., Simpson S.G., Addington A.M., et al. Genome-wide scan of bipolar disorder in 65 pedigrees. Supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12. Mol Psychiatry 8 (2003) 288-298
    • (2003) Mol Psychiatry , vol.8 , pp. 288-298
    • McInnis, M.G.1    Lan, T.H.2    Willour, V.L.3    McMahon, F.J.4    Simpson, S.G.5    Addington, A.M.6
  • 34
    • 17744391567 scopus 로고    scopus 로고
    • Genomic structure and localization within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia
    • Millar J.K., Christie S., Anderson S., Lawson D., Hsiao-Wei Loh D., Devon R.S., et al. Genomic structure and localization within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia. Mol Psychiatry 6 (2001) 173-178
    • (2001) Mol Psychiatry , vol.6 , pp. 173-178
    • Millar, J.K.1    Christie, S.2    Anderson, S.3    Lawson, D.4    Hsiao-Wei Loh, D.5    Devon, R.S.6
  • 35
    • 0242437914 scopus 로고    scopus 로고
    • Yeast two-hybrid screens implicate DISC1 in brain development and function
    • Millar J.K., Christie S., and Porteous D.J. Yeast two-hybrid screens implicate DISC1 in brain development and function. Biochem Biophys Res Commun 311 (2003) 1019-1025
    • (2003) Biochem Biophys Res Commun , vol.311 , pp. 1019-1025
    • Millar, J.K.1    Christie, S.2    Porteous, D.J.3
  • 36
    • 27944502874 scopus 로고    scopus 로고
    • DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
    • Millar J.K., Pickard B.S., Mackie S., James R., Christie S., Buchanan S.R., et al. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 310 (2005) 1187-1191
    • (2005) Science , vol.310 , pp. 1187-1191
    • Millar, J.K.1    Pickard, B.S.2    Mackie, S.3    James, R.4    Christie, S.5    Buchanan, S.R.6
  • 39
    • 0042622356 scopus 로고    scopus 로고
    • Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth
    • Miyoshi K., Honda A., Baba K., Taniguchi M., Oono K., Fujita T., et al. Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol Psychiatry 8 (2003) 685-694
    • (2003) Mol Psychiatry , vol.8 , pp. 685-694
    • Miyoshi, K.1    Honda, A.2    Baba, K.3    Taniguchi, M.4    Oono, K.5    Fujita, T.6
  • 40
    • 0037766786 scopus 로고    scopus 로고
    • DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL. Regulation and loss of interaction with mutation
    • Morris J.A., Kandpal G., Ma L., and Austin C.P. DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL. Regulation and loss of interaction with mutation. Hum Mol Genet 12 (2003) 1591-1608
    • (2003) Hum Mol Genet , vol.12 , pp. 1591-1608
    • Morris, J.A.1    Kandpal, G.2    Ma, L.3    Austin, C.P.4
  • 41
    • 8444250206 scopus 로고    scopus 로고
    • Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia
    • Numakawa T., Yagasaki Y., Ishimoto T., Okada T., Suzuki T., Iwata N., et al. Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Hum Mol Genet 13 (2004) 2699-2708
    • (2004) Hum Mol Genet , vol.13 , pp. 2699-2708
    • Numakawa, T.1    Yagasaki, Y.2    Ishimoto, T.3    Okada, T.4    Suzuki, T.5    Iwata, N.6
  • 42
    • 0031443561 scopus 로고    scopus 로고
    • Neuregulin-beta induces expression of an NMDA-receptor subunit
    • Ozaki M., Sasner M., Yano R., Lu H.S., and Buonanno A. Neuregulin-beta induces expression of an NMDA-receptor subunit. Nature 390 (1997) 691-694
    • (1997) Nature , vol.390 , pp. 691-694
    • Ozaki, M.1    Sasner, M.2    Yano, R.3    Lu, H.S.4    Buonanno, A.5
  • 43
    • 0037422609 scopus 로고    scopus 로고
    • Disrupted-in-Schizophrenia-1 (DISC-1). Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth
    • Ozeki Y., Tomoda T., Kleiderlein J., Kamiya A., Bord L., Fujii K., et al. Disrupted-in-Schizophrenia-1 (DISC-1). Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc Natl Acad Sci U S A 100 (2003) 289-294
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 289-294
    • Ozeki, Y.1    Tomoda, T.2    Kleiderlein, J.3    Kamiya, A.4    Bord, L.5    Fujii, K.6
  • 44
    • 0030425881 scopus 로고    scopus 로고
    • Conditional mutagenesis in mice. The Cre/loxP recombination system
    • Pluck A. Conditional mutagenesis in mice. The Cre/loxP recombination system. Int J Exp Pathol 77 (1996) 269-278
    • (1996) Int J Exp Pathol , vol.77 , pp. 269-278
    • Pluck, A.1
  • 45
    • 0031943325 scopus 로고    scopus 로고
    • Schizophrenia as a developmental disorder of the cerebral cortex
    • Raedler T.J., Knable M.B., and Weinberger D.R. Schizophrenia as a developmental disorder of the cerebral cortex. Curr Opin Neurobiol 8 (1998) 157-161
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 157-161
    • Raedler, T.J.1    Knable, M.B.2    Weinberger, D.R.3
  • 46
    • 0030750450 scopus 로고    scopus 로고
    • Neuregulin and erbB receptors play a critical role in neuronal migration
    • Rio C., Rieff H.I., Qi P., Khurana T.S., and Corfas G. Neuregulin and erbB receptors play a critical role in neuronal migration. Neuron 19 (1997) 39-50
    • (1997) Neuron , vol.19 , pp. 39-50
    • Rio, C.1    Rieff, H.I.2    Qi, P.3    Khurana, T.S.4    Corfas, G.5
  • 47
    • 23744517093 scopus 로고    scopus 로고
    • A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder
    • Sachs N.A., Sawa A., Holmes S.E., Ross C.A., Delisi L.E., and Margolis R.L. A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Mol Psychiatry 10 (2005) 758-764
    • (2005) Mol Psychiatry , vol.10 , pp. 758-764
    • Sachs, N.A.1    Sawa, A.2    Holmes, S.E.3    Ross, C.A.4    Delisi, L.E.5    Margolis, R.L.6
  • 48
    • 0141789635 scopus 로고    scopus 로고
    • Elucidating the pathogenesis of schizophrenia
    • Sawa A., and Kamiya A. Elucidating the pathogenesis of schizophrenia. BMJ 327 (2003) 632-633
    • (2003) BMJ , vol.327 , pp. 632-633
    • Sawa, A.1    Kamiya, A.2
  • 49
    • 2542507335 scopus 로고    scopus 로고
    • Neuron-glia interactions clarify genetic-environmental links in mental illness
    • Sawa A., Pletnikov M.V., and Kamiya A. Neuron-glia interactions clarify genetic-environmental links in mental illness. Trends Neurosci 27 (2004) 294-297
    • (2004) Trends Neurosci , vol.27 , pp. 294-297
    • Sawa, A.1    Pletnikov, M.V.2    Kamiya, A.3
  • 50
    • 0037177552 scopus 로고    scopus 로고
    • Schizophrenia. Diverse approaches to a complex disease
    • Sawa A., and Snyder S.H. Schizophrenia. Diverse approaches to a complex disease. Science 296 (2002) 692-695
    • (2002) Science , vol.296 , pp. 692-695
    • Sawa, A.1    Snyder, S.H.2
  • 51
    • 27944502891 scopus 로고    scopus 로고
    • Genetics. Two genes link two distinct psychoses
    • Sawa A., and Snyder S.H. Genetics. Two genes link two distinct psychoses. Science 310 (2005) 1128-1129
    • (2005) Science , vol.310 , pp. 1128-1129
    • Sawa, A.1    Snyder, S.H.2
  • 52
    • 12844265300 scopus 로고    scopus 로고
    • A form of DISC1 enriched in nucleus. Altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse
    • Sawamura N., Sawamura-Yamamoto T., Ozeki Y., Ross C.A., and Sawa A. A form of DISC1 enriched in nucleus. Altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proc Natl Acad Sci U S A 102 (2005) 1187-1192
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 1187-1192
    • Sawamura, N.1    Sawamura-Yamamoto, T.2    Ozeki, Y.3    Ross, C.A.4    Sawa, A.5
  • 53
    • 11244277000 scopus 로고    scopus 로고
    • Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment
    • Schurov I.L., Handford E.J., Brandon N.J., and Whiting P.J. Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment. Mol Psychiatry 9 (2004) 1100-1110
    • (2004) Mol Psychiatry , vol.9 , pp. 1100-1110
    • Schurov, I.L.1    Handford, E.J.2    Brandon, N.J.3    Whiting, P.J.4
  • 54
    • 5144228139 scopus 로고    scopus 로고
    • Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning
    • Shu T., Ayala R., Nguyen M.D., Xie Z., Gleeson J.G., and Tsai L.H. Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning. Neuron 44 (2004) 263-277
    • (2004) Neuron , vol.44 , pp. 263-277
    • Shu, T.1    Ayala, R.2    Nguyen, M.D.3    Xie, Z.4    Gleeson, J.G.5    Tsai, L.H.6
  • 56
    • 0035804770 scopus 로고    scopus 로고
    • Efficient in utero gene transfer system to the developing mouse brain using electroporation. Visualization of neuronal migration in the developing cortex
    • Tabata H., and Nakajima K. Efficient in utero gene transfer system to the developing mouse brain using electroporation. Visualization of neuronal migration in the developing cortex. Neuroscience 103 (2001) 865-872
    • (2001) Neuroscience , vol.103 , pp. 865-872
    • Tabata, H.1    Nakajima, K.2
  • 57
    • 2342512304 scopus 로고    scopus 로고
    • Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia
    • Talbot K., Eidem W.L., Tinsley C.L., Benson M.A., Thompson E.W., Smith R.J., et al. Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. J Clin Invest 113 (2004) 1353-1363
    • (2004) J Clin Invest , vol.113 , pp. 1353-1363
    • Talbot, K.1    Eidem, W.L.2    Tinsley, C.L.3    Benson, M.A.4    Thompson, E.W.5    Smith, R.J.6
  • 59
    • 0037289166 scopus 로고    scopus 로고
    • Evolutionary constraints on the disrupted in schizophrenia locus
    • Taylor M.S., Devon R.S., Millar J.K., and Porteous D.J. Evolutionary constraints on the disrupted in schizophrenia locus. Genomics 81 (2003) 67-77
    • (2003) Genomics , vol.81 , pp. 67-77
    • Taylor, M.S.1    Devon, R.S.2    Millar, J.K.3    Porteous, D.J.4
  • 61
    • 0033582171 scopus 로고    scopus 로고
    • Failure of spinal cord oligodendrocyte development in mice lacking neuregulin
    • Vartanian T., Fischbach G., and Miller R. Failure of spinal cord oligodendrocyte development in mice lacking neuregulin. Proc Natl Acad Sci U S A 96 (1999) 731-735
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 731-735
    • Vartanian, T.1    Fischbach, G.2    Miller, R.3
  • 62
    • 0042329506 scopus 로고    scopus 로고
    • Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration
    • Xie Z., Sanada K., Samuels B.A., Shih H., and Tsai L.H. Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. Cell 114 (2003) 469-482
    • (2003) Cell , vol.114 , pp. 469-482
    • Xie, Z.1    Sanada, K.2    Samuels, B.A.3    Shih, H.4    Tsai, L.H.5
  • 64
    • 26844476910 scopus 로고    scopus 로고
    • Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population
    • Zhang X., Tochigi M., Ohashi J., Maeda K., Kato T., Okazaki Y., et al. Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population. Schizophr Res 79 (2005) 175-180
    • (2005) Schizophr Res , vol.79 , pp. 175-180
    • Zhang, X.1    Tochigi, M.2    Ohashi, J.3    Maeda, K.4    Kato, T.5    Okazaki, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.