메뉴 건너뛰기




Volumn 38, Issue 2, 2013, Pages 98-106

Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive tasks

Author keywords

[No Author keywords available]

Indexed keywords

CANNABIS; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; NAXAGOLIDE; TRACER; DOPAMINE RECEPTOR STIMULATING AGENT; OXAZINE DERIVATIVE;

EID: 84874335378     PISSN: 11804882     EISSN: 14882434     Source Type: Journal    
DOI: 10.1503/jpn.110181     Document Type: Article
Times cited : (32)

References (63)
  • 1
    • 0028983794 scopus 로고
    • No elevated D2 dopamine receptors in neuroleptic-naive schizophrenic patients revealed by positron emission tomography and [11C]N-methyl-spiperone
    • Nordström AL, Farde L, Eriksson L, et al. No elevated D2 dopamine receptors in neuroleptic-naive schizophrenic patients revealed by positron emission tomography and [11C]N-methyl-spiperone. Psychiatry Res 1995;61:67-83.
    • (1995) Psychiatry Res , vol.61 , pp. 67-83
    • Nordström, A.L.1    Farde, L.2    Eriksson, L.3
  • 2
    • 0027787426 scopus 로고
    • Dopamine D2 receptor density estimates in schizophrenia: A positron emission tomography study with 11C-N-methylspiperone
    • Tune LE, Wong DF, Pearlson G, et al. Dopamine D2 receptor density estimates in schizophrenia: a positron emission tomography study with 11C-N-methylspiperone. Psychiatry Res 1993;49:219-37.
    • (1993) Psychiatry Res , vol.49 , pp. 219-237
    • Tune, L.E.1    Wong, D.F.2    Pearlson, G.3
  • 3
    • 0028167490 scopus 로고
    • Striatal D2 dopamine receptor characteristics in neuroleptic-naive schizophrenic patients studied with positron emission tomography
    • Hietala J, Syvalahti E, Vuorio K, et al. Striatal D2 dopamine receptor characteristics in neuroleptic-naive schizophrenic patients studied with positron emission tomography. Arch Gen Psychiatry 1994;51:116-23.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 116-123
    • Hietala, J.1    Syvalahti, E.2    Vuorio, K.3
  • 4
    • 0034774737 scopus 로고    scopus 로고
    • Dopamine receptors in the brains of schizophrenia patients: A meta-analysis of the findings
    • Kestler LP, Walker E, Vega EM. Dopamine receptors in the brains of schizophrenia patients: a meta-analysis of the findings. Behav Pharmacol 2001;12:355-71.
    • (2001) Behav Pharmacol , vol.12 , pp. 355-371
    • Kestler, L.P.1    Walker, E.2    Vega, E.M.3
  • 5
    • 0031791214 scopus 로고    scopus 로고
    • Imaging dopamine transmission in schizophrenia. A review and meta-analysis
    • Laruelle M. Imaging dopamine transmission in schizophrenia. A review and meta-analysis. Q J Nucl Med 1998;42:211-21.
    • (1998) Q J Nucl Med , vol.42 , pp. 211-221
    • Laruelle, M.1
  • 6
    • 0023027609 scopus 로고
    • Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics
    • Wong DF, Wagner HN Jr, Tune LE, et al. Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics. Science 1986;234:1558-63.
    • (1986) Science , vol.234 , pp. 1558-1563
    • Wong, D.F.1    Wagner Jr., H.N.2    Tune, L.E.3
  • 7
    • 20044378114 scopus 로고    scopus 로고
    • Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis
    • Seeman P, Weinshenker D, Quirion R, et al. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proc Natl Acad Sci U S A 2005;102:3513-8.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3513-3518
    • Seeman, P.1    Weinshenker, D.2    Quirion, R.3
  • 8
    • 20444379220 scopus 로고    scopus 로고
    • Radiosynthesis and evaluation of [11C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2Hnaphtho[1,2-b][1,4]oxazin-9-ol as a potential radiotracer for in vivo imaging of the dopamine D2 high-affinity state with positron emission tomography
    • Wilson AA, McCormick P, Kapur S, et al. Radiosynthesis and evaluation of [11C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2Hnaphtho[1,2-b][1,4]oxazin-9-ol as a potential radiotracer for in vivo imaging of the dopamine D2 high-affinity state with positron emission tomography. J Med Chem 2005;48:4153-60.
    • (2005) J Med Chem , vol.48 , pp. 4153-4160
    • Wilson, A.A.1    McCormick, P.2    Kapur, S.3
  • 9
    • 33344454906 scopus 로고    scopus 로고
    • High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C] (+)-PHNO
    • Willeit M, Ginovart N, Kapur S, et al. High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C] (+)-PHNO. Biol Psychiatry 2006;59:389-94.
    • (2006) Biol Psychiatry , vol.59 , pp. 389-394
    • Willeit, M.1    Ginovart, N.2    Kapur, S.3
  • 10
    • 77955710668 scopus 로고    scopus 로고
    • Imaging dopamine D3 receptors in the human brain with positron emission tomography, [11C]PHNO, and a selective D3 receptor antagonist
    • Searle G, Beaver JD, Comley RA, et al. Imaging dopamine D3 receptors in the human brain with positron emission tomography, [11C]PHNO, and a selective D3 receptor antagonist. Biol Psychiatry 2010;68:392-9.
    • (2010) Biol Psychiatry , vol.68 , pp. 392-399
    • Searle, G.1    Beaver, J.D.2    Comley, R.A.3
  • 11
    • 77957949636 scopus 로고    scopus 로고
    • Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy
    • Tziortzi AC, Searle GE, Tzimopoulou S, et al. Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy. Neuroimage 2011;54:264-77.
    • (2011) Neuroimage , vol.54 , pp. 264-277
    • Tziortzi, A.C.1    Searle, G.E.2    Tzimopoulou, S.3
  • 12
    • 84862802562 scopus 로고    scopus 로고
    • Affinity and selectivity of [(11) C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo
    • Gallezot JD, Beaver JD, Gunn RN, et al. Affinity and selectivity of [(11) C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo. Synapse 2012;66:489-500.
    • (2012) Synapse , vol.66 , pp. 489-500
    • Gallezot, J.D.1    Beaver, J.D.2    Gunn, R.N.3
  • 13
    • 68049134258 scopus 로고    scopus 로고
    • In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice
    • Rabiner EA, Slifstein M, Nobrega J, et al. In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice. Synapse 2009; 63:782-93.
    • (2009) Synapse , vol.63 , pp. 782-793
    • Rabiner, E.A.1    Slifstein, M.2    Nobrega, J.3
  • 14
    • 81555213468 scopus 로고    scopus 로고
    • Dopamine agonist radioligand binds to both D2High and D2Low receptors, explaining why alterations in D2High are not detected in human brain scans
    • Seeman P. Dopamine agonist radioligand binds to both D2High and D2Low receptors, explaining why alterations in D2High are not detected in human brain scans. Synapse 2012;66:88-93.
    • (2012) Synapse , vol.66 , pp. 88-93
    • Seeman, P.1
  • 15
    • 0027185464 scopus 로고
    • Dopamine receptors labeled by PHNO
    • Seeman P, Ulpian C, Larsen RD, et al. Dopamine receptors labeled by PHNO. Synapse 1993;14:254-62.
    • (1993) Synapse , vol.14 , pp. 254-262
    • Seeman, P.1    Ulpian, C.2    Larsen, R.D.3
  • 16
    • 0028357693 scopus 로고
    • Dopamine D2 receptors mapped in rat brain with [3H](+)PHNO
    • Nobrega JN, Seeman P. Dopamine D2 receptors mapped in rat brain with [3H](+)PHNO. Synapse 1994;17:167-72.
    • (1994) Synapse , vol.17 , pp. 167-172
    • Nobrega, J.N.1    Seeman, P.2
  • 17
    • 37349028845 scopus 로고    scopus 로고
    • Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo
    • McCormick PN, Kapur S, Seeman P, et al. Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo. Nucl Med Biol 2008;35:11-7.
    • (2008) Nucl Med Biol , vol.35 , pp. 11-17
    • McCormick, P.N.1    Kapur, S.2    Seeman, P.3
  • 18
    • 84855342146 scopus 로고    scopus 로고
    • Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans
    • Shotbolt P, Tziortzi AC, Searle GE, et al. Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans. J Cereb Blood Flow Metab 2012;32:127-36.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 127-136
    • Shotbolt, P.1    Tziortzi, A.C.2    Searle, G.E.3
  • 19
    • 59949098994 scopus 로고    scopus 로고
    • The dopamine D2 receptors in high-affinity state and D3 receptors in schizophrenia: A clinical [11C]-(+)-PHNO PET study
    • Graff-Guerrero A, Mizrahi R, Agid O, et al. The dopamine D2 receptors in high-affinity state and D3 receptors in schizophrenia: a clinical [11C]-(+)-PHNO PET study. Neuropsychopharmacology 2009;34:1078-86.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1078-1086
    • Graff-Guerrero, A.1    Mizrahi, R.2    Agid, O.3
  • 20
    • 61349189549 scopus 로고    scopus 로고
    • Dopamine release in the human striatum: Motor and cognitive tasks revisited
    • Lappin JM, Reeves SJ, Mehta MA, et al. Dopamine release in the human striatum: motor and cognitive tasks revisited. J Cereb Blood Flow Metab 2009;29:554-64.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 554-564
    • Lappin, J.M.1    Reeves, S.J.2    Mehta, M.A.3
  • 21
    • 0031799667 scopus 로고    scopus 로고
    • Increased striatal dopamine transmission in schizophrenia: Confirmation in a second cohort
    • Abi-Dargham A, Gil R, Krystal J, et al. Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort. Am J Psychiatry 1998;155:761-7.
    • (1998) Am J Psychiatry , vol.155 , pp. 761-767
    • Abi-Dargham, A.1    Gil, R.2    Krystal, J.3
  • 22
    • 0032987267 scopus 로고    scopus 로고
    • Increased dopamine transmission in schizophrenia: Relationship to illness phases
    • Laruelle M, Abi-Dargham A, Gil R, et al. Increased dopamine transmission in schizophrenia: relationship to illness phases. Biol Psychiatry 1999;46:56-72.
    • (1999) Biol Psychiatry , vol.46 , pp. 56-72
    • Laruelle, M.1    Abi-Dargham, A.2    Gil, R.3
  • 23
    • 34547627697 scopus 로고    scopus 로고
    • North American Prodrome Longitudinal Study: A collaborative multisite approach to prodromal schizophrenia research
    • Addington J, Cadenhead KS, Cannon TD, et al. North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research. Schizophr Bull 2007;33:665-72.
    • (2007) Schizophr Bull , vol.33 , pp. 665-672
    • Addington, J.1    Cadenhead, K.S.2    Cannon, T.D.3
  • 24
    • 38049108277 scopus 로고    scopus 로고
    • Prediction of psychosis in youth at high clinical risk: A multisite longitudinal study in North America
    • Cannon TD, Cadenhead K, Cornblatt B, et al. Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch Gen Psychiatry 2008;65:28-37.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 28-37
    • Cannon, T.D.1    Cadenhead, K.2    Cornblatt, B.3
  • 25
    • 84857633601 scopus 로고    scopus 로고
    • Increased stress-induced dopamine release in psychosis
    • Mizrahi R, Addington J, Rusjan PM, et al. Increased stress-induced dopamine release in psychosis. Biol Psychiatry 2012;71:561-7.
    • (2012) Biol Psychiatry , vol.71 , pp. 561-567
    • Mizrahi, R.1    Addington, J.2    Rusjan, P.M.3
  • 26
    • 0036241144 scopus 로고    scopus 로고
    • Prospective diagnosis of the initial prodrome for schizophrenia based on the Structured Interview for Prodromal Syndromes: Preliminary evidence of interrater reliability and predictive validity
    • Miller TJ, McGlashan TH, Rosen JL, et al. Prospective diagnosis of the initial prodrome for schizophrenia based on the Structured Interview for Prodromal Syndromes: preliminary evidence of interrater reliability and predictive validity. Am J Psychiatry 2002;159:863-5.
    • (2002) Am J Psychiatry , vol.159 , pp. 863-865
    • Miller, T.J.1    McGlashan, T.H.2    Rosen, J.L.3
  • 28
    • 0003412410 scopus 로고
    • Rockville (MD): U.S. Dept. of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute of Mental Health, Psychopharmacology Research Branch, Division of Extramural Research Programs
    • Guy W. ECDEU assessment manual for psychopharmacology. Rockville (MD): U.S. Dept. of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute of Mental Health, Psychopharmacology Research Branch, Division of Extramural Research Programs; 1976.
    • (1976) ECDEU Assessment Manual For Psychopharmacology
    • Guy, W.1
  • 29
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987;13:261-76.
    • (1987) Schizophr Bull , vol.13 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 30
    • 1642315257 scopus 로고    scopus 로고
    • Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: A positron emission tomography study using [11C]raclopride
    • Pruessner JC, Champagne F, Meaney MJ, et al. Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: a positron emission tomography study using [11C]raclopride. J Neurosci 2004;24:2825-31.
    • (2004) J Neurosci , vol.24 , pp. 2825-2831
    • Pruessner, J.C.1    Champagne, F.2    Meaney, M.J.3
  • 31
    • 0034840454 scopus 로고    scopus 로고
    • Imaging human mesolimbic dopamine transmission with positron emission tomography: I. Accuracy and precision of D(2) receptor parameter measurements in ventral striatum
    • Mawlawi O, Martinez D, Slifstein M, et al. Imaging human mesolimbic dopamine transmission with positron emission tomography: I. Accuracy and precision of D(2) receptor parameter measurements in ventral striatum. J Cereb Blood Flow Metab 2001;21:1034-57.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1034-1057
    • Mawlawi, O.1    Martinez, D.2    Slifstein, M.3
  • 32
    • 0037342436 scopus 로고    scopus 로고
    • Imaging human mesolimbic dopamine transmission with positron emission tomography. Part II: Amphetamine-induced dopamine release in the functional subdivisions of the striatum
    • Martinez D, Slifstein M, Broft A, et al. Imaging human mesolimbic dopamine transmission with positron emission tomography. Part II: amphetamine-induced dopamine release in the functional subdivisions of the striatum. J Cereb Blood Flow Metab 2003;23:285-300.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 285-300
    • Martinez, D.1    Slifstein, M.2    Broft, A.3
  • 33
    • 33746008824 scopus 로고    scopus 로고
    • An automated method for the extraction of regional data from PET images
    • Rusjan P, Mamo D, Ginovart N, et al. An automated method for the extraction of regional data from PET images. Psychiatry Res 2006;147:79-89.
    • (2006) Psychiatry Res , vol.147 , pp. 79-89
    • Rusjan, P.1    Mamo, D.2    Ginovart, N.3
  • 34
    • 0030468875 scopus 로고    scopus 로고
    • Simplified reference tissue model for PET receptor studies
    • Lammertsma AA, Hume SP. Simplified reference tissue model for PET receptor studies. Neuroimage 1996;4:153-8.
    • (1996) Neuroimage , vol.4 , pp. 153-158
    • Lammertsma, A.A.1    Hume, S.P.2
  • 35
    • 33947537467 scopus 로고    scopus 로고
    • Positron emission tomography quantification of [11C]-(+)-PHNO binding in the human brain
    • Ginovart N, Willeit M, Rusjan P, et al. Positron emission tomography quantification of [11C]-(+)-PHNO binding in the human brain. J Cereb Blood Flow Metab 2007;27:857-71.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 857-871
    • Ginovart, N.1    Willeit, M.2    Rusjan, P.3
  • 36
    • 0036898646 scopus 로고    scopus 로고
    • Positron emission tomography compartmental models: A basis pursuit strategy for kinetic modeling
    • Gunn RN, Gunn SR, Turkheimer FE, et al. Positron emission tomography compartmental models: a basis pursuit strategy for kinetic modeling. J Cereb Blood Flow Metab 2002;22:1425-39.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1425-1439
    • Gunn, R.N.1    Gunn, S.R.2    Turkheimer, F.E.3
  • 37
    • 0024251009 scopus 로고
    • Workshop on schizophrenia, PET, and dopamine D2 receptors in the human neostriatum
    • Andreasen NC, Carson R, Diksic M, et al. Workshop on schizophrenia, PET, and dopamine D2 receptors in the human neostriatum. Schizophr Bull 1988;14:471-84.
    • (1988) Schizophr Bull , vol.14 , pp. 471-484
    • Andreasen, N.C.1    Carson, R.2    Diksic, M.3
  • 38
    • 0025194556 scopus 로고
    • D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride
    • Farde L, Wiesel FA, Stone-Elander S, et al. D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride. Arch Gen Psychiatry 1990;47:213-9.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 213-219
    • Farde, L.1    Wiesel, F.A.2    Stone-Elander, S.3
  • 39
    • 0032554885 scopus 로고    scopus 로고
    • Evidence for striatal dopamine release during a video game
    • Koepp MJ, Gunn RN, Lawrence AD, et al. Evidence for striatal dopamine release during a video game. Nature 1998;393:266-8.
    • (1998) Nature , vol.393 , pp. 266-268
    • Koepp, M.J.1    Gunn, R.N.2    Lawrence, A.D.3
  • 40
    • 0034608753 scopus 로고    scopus 로고
    • Increased baseline occupancy of D2 receptors by dopamine in schizophrenia
    • Abi-Dargham A, Rodenhiser J, Printz D, et al. Increased baseline occupancy of D2 receptors by dopamine in schizophrenia. Proc Natl Acad Sci U S A 2000;97:8104-9.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8104-8109
    • Abi-Dargham, A.1    Rodenhiser, J.2    Printz, D.3
  • 41
    • 0020641659 scopus 로고
    • Dopamine receptor binding on intact cells. Absence of a high-affinity agonist-receptor binding state
    • Sibley DR, Mahan LC, Creese I. Dopamine receptor binding on intact cells. Absence of a high-affinity agonist-receptor binding state. Mol Pharmacol 1983;23:295-302.
    • (1983) Mol Pharmacol , vol.23 , pp. 295-302
    • Sibley, D.R.1    Mahan, L.C.2    Creese, I.3
  • 42
    • 40449143083 scopus 로고    scopus 로고
    • Dopamine D2(High) receptors on intact cells
    • Seeman P. Dopamine D2(High) receptors on intact cells. Synapse 2008;62:314-8.
    • (2008) Synapse , vol.62 , pp. 314-318
    • Seeman, P.1
  • 43
    • 25644454408 scopus 로고    scopus 로고
    • Measurement of the proportion of D2 receptors configured in state of high affinity for agonists in vivo: A positron emission tomography study using [11C]N-propyl-norapomorphine and [11C]raclopride in baboons
    • Narendran R, Hwang DR, Slifstein M, et al. Measurement of the proportion of D2 receptors configured in state of high affinity for agonists in vivo: a positron emission tomography study using [11C]N-propyl-norapomorphine and [11C]raclopride in baboons. J Pharmacol Exp Ther 2005;315:80-90.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 80-90
    • Narendran, R.1    Hwang, D.R.2    Slifstein, M.3
  • 44
    • 33646078787 scopus 로고    scopus 로고
    • Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography
    • Ginovart N, Galineau L, Willeit M, et al. Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography. J Neurochem 2006;97:1089-103.
    • (2006) J Neurochem , vol.97 , pp. 1089-1103
    • Ginovart, N.1    Galineau, L.2    Willeit, M.3
  • 45
    • 2342595176 scopus 로고    scopus 로고
    • In vivo vulnerability to competition by endogenous dopamine: Comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C] raclopride
    • Narendran R, Hwang DR, Slifstein M, et al. In vivo vulnerability to competition by endogenous dopamine: Comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C] raclopride. Synapse 2004;52:188-208.
    • (2004) Synapse , vol.52 , pp. 188-208
    • Narendran, R.1    Hwang, D.R.2    Slifstein, M.3
  • 46
    • 33144467375 scopus 로고    scopus 로고
    • Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: A comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride
    • Seneca N, Finnema SJ, Farde L, et al. Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride. Synapse 2006;59:260-9.
    • (2006) Synapse , vol.59 , pp. 260-269
    • Seneca, N.1    Finnema, S.J.2    Farde, L.3
  • 47
    • 36949036673 scopus 로고    scopus 로고
    • First human evidence of damphetamine induced displacement of a D(2/3) agonist radioligand: A [(11)C]-(+)-PHNO positron emission tomography study
    • Willeit M, Ginovart N, Graff A, et al. First human evidence of damphetamine induced displacement of a D(2/3) agonist radioligand: a [(11)C]-(+)-PHNO positron emission tomography study. Neuropsychopharmacology 2008;33:279-89.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 279-289
    • Willeit, M.1    Ginovart, N.2    Graff, A.3
  • 48
    • 77951088919 scopus 로고    scopus 로고
    • A comparative evaluation of the dopamine D(2/3) agonist radiotracer [11C](-)-Npropyl-norapomorphine and antagonist [11C]raclopride to measure amphetamine-induced dopamine release in the human striatum
    • Narendran R, Mason NS, Laymon CM, et al. A comparative evaluation of the dopamine D(2/3) agonist radiotracer [11C](-)-Npropyl-norapomorphine and antagonist [11C]raclopride to measure amphetamine-induced dopamine release in the human striatum. J Pharmacol Exp Ther 2010;333:533-539.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 533-539
    • Narendran, R.1    Mason, N.S.2    Laymon, C.M.3
  • 49
    • 66049089990 scopus 로고    scopus 로고
    • Dopamine D(2/3) receptor occupancy of apomorphine in the nonhuman primate brain-a comparative PET study with [11C]raclopride and [11C]MNPA
    • Finnema SJ, Halldin C, Bang-Andersen B, et al. Dopamine D(2/3) receptor occupancy of apomorphine in the nonhuman primate brain-a comparative PET study with [11C]raclopride and [11C]MNPA. Synapse 2009;63:378-89.
    • (2009) Synapse , vol.63 , pp. 378-389
    • Finnema, S.J.1    Halldin, C.2    Bang-Andersen, B.3
  • 50
    • 0023371177 scopus 로고
    • No D2 receptor increase in PET study of schizophrenia
    • Farde L, Wiesel FA, Hall H, et al. No D2 receptor increase in PET study of schizophrenia. Arch Gen Psychiatry 1987;44:671-2.
    • (1987) Arch Gen Psychiatry , vol.44 , pp. 671-672
    • Farde, L.1    Wiesel, F.A.2    Hall, H.3
  • 51
    • 33745375661 scopus 로고    scopus 로고
    • D2/D3 dopamine receptor binding with [F-18]fallypride in thalamus and cortex of patients with schizophrenia
    • Buchsbaum MS, Christian BT, Lehrer DS, et al. D2/D3 dopamine receptor binding with [F-18]fallypride in thalamus and cortex of patients with schizophrenia. Schizophr Res 2006;85:232-44.
    • (2006) Schizophr Res , vol.85 , pp. 232-244
    • Buchsbaum, M.S.1    Christian, B.T.2    Lehrer, D.S.3
  • 52
    • 67349219375 scopus 로고    scopus 로고
    • Dopamine D2 receptor levels in striatum, thalamus, substantia nigra, limbic regions, and cortex in schizophrenic subjects
    • Kessler RM, Woodward ND, Riccardi P, et al. Dopamine D2 receptor levels in striatum, thalamus, substantia nigra, limbic regions, and cortex in schizophrenic subjects. Biol Psychiatry 2009;65:1024-31.
    • (2009) Biol Psychiatry , vol.65 , pp. 1024-1031
    • Kessler, R.M.1    Woodward, N.D.2    Riccardi, P.3
  • 53
    • 2942615018 scopus 로고    scopus 로고
    • Low dopamine d(2) receptor binding in subregions of the thalamus in schizophrenia
    • Yasuno F, Suhara T, Okubo Y, et al. Low dopamine d(2) receptor binding in subregions of the thalamus in schizophrenia. Am J Psychiatry 2004;161:1016-22.
    • (2004) Am J Psychiatry , vol.161 , pp. 1016-1022
    • Yasuno, F.1    Suhara, T.2    Okubo, Y.3
  • 54
    • 77956937214 scopus 로고    scopus 로고
    • Striatal and extrastriatal dopamine D2/D3 receptors in schizophrenia evaluated with [18F]fallypride positron emission tomography
    • Kegeles LS, Slifstein M, Xu X, et al. Striatal and extrastriatal dopamine D2/D3 receptors in schizophrenia evaluated with [18F]fallypride positron emission tomography. Biol Psychiatry 2010;68:634-41.
    • (2010) Biol Psychiatry , vol.68 , pp. 634-641
    • Kegeles, L.S.1    Slifstein, M.2    Xu, X.3
  • 55
    • 33748741284 scopus 로고    scopus 로고
    • Frontal dopamine D(2/3) receptor binding in drug-naive first-episode schizophrenic patients correlates with positive psychotic symptoms and gender
    • Glenthoj BY, Mackeprang T, Svarer C, et al. Frontal dopamine D(2/3) receptor binding in drug-naive first-episode schizophrenic patients correlates with positive psychotic symptoms and gender. Biol Psychiatry 2006;60:621-9.
    • (2006) Biol Psychiatry , vol.60 , pp. 621-629
    • Glenthoj, B.Y.1    Mackeprang, T.2    Svarer, C.3
  • 56
    • 0742288285 scopus 로고    scopus 로고
    • Decreased thalamic D2/D3 receptor binding in drug-naive patients with schizophrenia: A PET study with [11C]FLB 457
    • Talvik M, Nordstrom AL, Olsson H, et al. Decreased thalamic D2/D3 receptor binding in drug-naive patients with schizophrenia: a PET study with [11C]FLB 457. Int J Neuropsychopharmacol 2003;6:361-70.
    • (2003) Int J Neuropsychopharmacol , vol.6 , pp. 361-370
    • Talvik, M.1    Nordstrom, A.L.2    Olsson, H.3
  • 57
    • 0028805490 scopus 로고
    • Presynaptic dopamine func-tion in striatum of neuroleptic-naive schizophrenic patients
    • Hietala J, Syvalahti E, Vuorio K, et al. Presynaptic dopamine func-tion in striatum of neuroleptic-naive schizophrenic patients. Lancet 1995;346:1130-1.
    • (1995) Lancet , vol.346 , pp. 1130-1131
    • Hietala, J.1    Syvalahti, E.2    Vuorio, K.3
  • 58
    • 0032802997 scopus 로고    scopus 로고
    • Increased dopamine synthesis rate in medial prefrontal cortex and striatum in schizophrenia indicated by L-(beta-11C) DOPA and PET
    • Lindström LH, Gefvert O, Hagberg G, et al. Increased dopamine synthesis rate in medial prefrontal cortex and striatum in schizophrenia indicated by L-(beta-11C) DOPA and PET. Biol Psychiatry 1999;46:681-8.
    • (1999) Biol Psychiatry , vol.46 , pp. 681-688
    • Lindström, L.H.1    Gefvert, O.2    Hagberg, G.3
  • 59
    • 0028072691 scopus 로고
    • Elevated dopa decarboxylase activity in living brain of patients with psychosis
    • Reith J, Benkelfat C, Sherwin A, et al. Elevated dopa decarboxylase activity in living brain of patients with psychosis. Proc Natl Acad Sci U S A 1994;91:11651-4.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11651-11654
    • Reith, J.1    Benkelfat, C.2    Sherwin, A.3
  • 60
    • 17544386853 scopus 로고    scopus 로고
    • Presynaptic dopaminergic function in the striatum of schizophrenic patients
    • Dao-Castellana MH, Paillere-Martinot ML, Hantraye P, et al. Presynaptic dopaminergic function in the striatum of schizophrenic patients. Schizophr Res 1997;23:167-74.
    • (1997) Schizophr Res , vol.23 , pp. 167-174
    • Dao-Castellana, M.H.1    Paillere-Martinot, M.L.2    Hantraye, P.3
  • 61
    • 58149489347 scopus 로고    scopus 로고
    • Elevated striatal dopamine function linked to prodromal signs of schizophrenia
    • Howes OD, Montgomery AJ, Asselin MC, et al. Elevated striatal dopamine function linked to prodromal signs of schizophrenia. Arch Gen Psychiatry 2009;66:13-20.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 13-20
    • Howes, O.D.1    Montgomery, A.J.2    Asselin, M.C.3
  • 62
    • 80052068381 scopus 로고    scopus 로고
    • Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: A PET study
    • Howes O, Bose S, Turkheimer F, et al. Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study. Mol Psychiatry 2011;16:885-6.
    • (2011) Mol Psychiatry , vol.16 , pp. 885-886
    • Howes, O.1    Bose, S.2    Turkheimer, F.3
  • 63
    • 80051787669 scopus 로고    scopus 로고
    • Effects of antipsychotics on D3 receptors: A clinical PET study in first episode antipsychotic naive patients with schizophrenia using [(11)C]-(+)-PHNO
    • Mizrahi R, Agid O, Borlido C, et al. Effects of antipsychotics on D3 receptors: a clinical PET study in first episode antipsychotic naive patients with schizophrenia using [(11)C]-(+)-PHNO. Schizophr Res 2011;131:63-8.
    • (2011) Schizophr Res , vol.131 , pp. 63-68
    • Mizrahi, R.1    Agid, O.2    Borlido, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.