메뉴 건너뛰기




Volumn 9, Issue 2, 2015, Pages 88-95

Meta-analysis of efficacy of mirtazapine as an adjunctive treatment of negative symptoms in schizophrenia

Author keywords

Meta analysis; Mirtazapine; Negative symptoms; Schizophrenia

Indexed keywords

HALOPERIDOL; MIRTAZAPINE; PLACEBO; MIANSERIN; NEUROLEPTIC AGENT; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 84936945435     PISSN: 19351232     EISSN: 19412010     Source Type: Journal    
DOI: 10.3371/CSRP.VIRE.030813     Document Type: Review
Times cited : (15)

References (32)
  • 2
    • 77958184946 scopus 로고    scopus 로고
    • Periods of recovery in deficit syndrome schizophrenia: A 20-year multi-follow-up longitudinal study
    • Strauss GP, Harrow M, Grossman LS, Rosen C. Periods of recovery in deficit syndrome schizophrenia: a 20-year multi-follow-up longitudinal study. Schizophr Bull 2010;36(4):788-799.
    • (2010) Schizophr Bull , vol.36 , Issue.4 , pp. 788-799
    • Strauss, G.P.1    Harrow, M.2    Grossman, L.S.3    Rosen, C.4
  • 3
    • 0028293198 scopus 로고
    • Antecedents, symptom progression, and long-term outcome of the deficit syndrome in schizophrenia
    • Fenton WS, McGlashan TH. Antecedents, symptom progression, and long-term outcome of the deficit syndrome in schizophrenia. Am J Psychiatry 1994;151(3):351-356.
    • (1994) Am J Psychiatry , vol.151 , Issue.3 , pp. 351-356
    • Fenton, W.S.1    McGlashan, T.H.2
  • 4
    • 33750625280 scopus 로고    scopus 로고
    • Pharmacological treatment of primary negative symptoms in schizophrenia: A systematic review
    • Murphy BP, Chung YC, Park TW, McGorry PD. Pharmacological treatment of primary negative symptoms in schizophrenia: a systematic review. Schizophr Res 2006;88(1-3):5-25.
    • (2006) Schizophr Res , vol.88 , Issue.1-3 , pp. 5-25
    • Murphy, B.P.1    Chung, Y.C.2    Park, T.W.3    McGorry, P.D.4
  • 5
    • 34249323746 scopus 로고    scopus 로고
    • The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: A double-blind, placebo-controlled study
    • Zoccali R, Muscatello MR, Bruno A, Cambria R, Mico U, Spina E, et al. The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: a double-blind, placebo-controlled study. Schizophr Res 2007;93(1-3);109-116.
    • (2007) Schizophr Res , vol.93 , Issue.1-3 , pp. 109-116
    • Zoccali, R.1    Muscatello, M.R.2    Bruno, A.3    Cambria, R.4    Mico, U.5    Spina, E.6
  • 6
    • 48749112603 scopus 로고    scopus 로고
    • N-acetyl cysteine as a glutathione precursor for schizophrenia - A double-blind, randomized, placebo-controlled trial
    • Berk M, Copolov D, Dean O, Lu K, Jeavons S, Schapkaitz I, et al. N-acetyl cysteine as a glutathione precursor for schizophrenia - a double-blind, randomized, placebo-controlled trial. Biol Psychiatry 2008;64(5):361-368.
    • (2008) Biol Psychiatry , vol.64 , Issue.5 , pp. 361-368
    • Berk, M.1    Copolov, D.2    Dean, O.3    Lu, K.4    Jeavons, S.5    Schapkaitz, I.6
  • 8
    • 0028080521 scopus 로고
    • Biochemical findings of negative symptoms in schizophrenia and their putative relevance to pharmacologic treatment. A review
    • Rao ML, Moller HJ. Biochemical findings of negative symptoms in schizophrenia and their putative relevance to pharmacologic treatment. A review. Neuropsychobiology 1994;30(4):160-172.
    • (1994) Neuropsychobiology , vol.30 , Issue.4 , pp. 160-172
    • Rao, M.L.1    Moller, H.J.2
  • 9
    • 0033845691 scopus 로고    scopus 로고
    • Fluvoxamine augmentation of antipsychotics improves negative symptoms in psychotic chronic schizophrenic patients: A placebo-controlled study
    • Silver H, Barash I, Aharon N, Kaplan A, Poyurovsky M. Fluvoxamine augmentation of antipsychotics improves negative symptoms in psychotic chronic schizophrenic patients: a placebo-controlled study. Int Clin Psychopharmacol 2000;15(5):257-261.
    • (2000) Int Clin Psychopharmacol , vol.15 , Issue.5 , pp. 257-261
    • Silver, H.1    Barash, I.2    Aharon, N.3    Kaplan, A.4    Poyurovsky, M.5
  • 10
    • 0037345841 scopus 로고    scopus 로고
    • The onset and time course of response of negative symptoms to add-on fluvoxamine treatment
    • Silver H, Nassar A, Aharon N, Kaplan A. The onset and time course of response of negative symptoms to add-on fluvoxamine treatment. Int Clin Psychopharmacol 2003;18(2):87-92.
    • (2003) Int Clin Psychopharmacol , vol.18 , Issue.2 , pp. 87-92
    • Silver, H.1    Nassar, A.2    Aharon, N.3    Kaplan, A.4
  • 12
    • 0008762402 scopus 로고    scopus 로고
    • A double-blind study of adjunctive sertraline in haloperidol-stabilized patients with chronic schizophrenia
    • Lee MS, Kim YK, Lee SK, Suh KY. A double-blind study of adjunctive sertraline in haloperidol-stabilized patients with chronic schizophrenia. J Clin Psychopharmacol 1998;18(5):399-403.
    • (1998) J Clin Psychopharmacol , vol.18 , Issue.5 , pp. 399-403
    • Lee, M.S.1    Kim, Y.K.2    Lee, S.K.3    Suh, K.Y.4
  • 13
    • 9844253332 scopus 로고    scopus 로고
    • Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: An add-on, double-blind, placebo-controlled study
    • Hayashi T, Yokota N, Takahashi T, Tawara Y, Nishikawa T, Yano T, et al. Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study. Int Clin Psychopharmacol 1997;12(4):199-205.
    • (1997) Int Clin Psychopharmacol , vol.12 , Issue.4 , pp. 199-205
    • Hayashi, T.1    Yokota, N.2    Takahashi, T.3    Tawara, Y.4    Nishikawa, T.5    Yano, T.6
  • 15
    • 34247538931 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor (SSRI) add-on therapy for the negative symptoms of schizophrenia: A meta-analysis
    • Sepehry AA, Potvin S, Elie R, Stip E. Selective serotonin reuptake inhibitor (SSRI) add-on therapy for the negative symptoms of schizophrenia: a meta-analysis. J Clin Psychiatry 2007;68(4):604-610.
    • (2007) J Clin Psychiatry , vol.68 , Issue.4 , pp. 604-610
    • Sepehry, A.A.1    Potvin, S.2    Elie, R.3    Stip, E.4
  • 16
    • 77956864079 scopus 로고    scopus 로고
    • Efficacy of antidepressants in treating the negative symptoms of chornic schizophrenia: Meta-analysis
    • Singh SP, Singh V, Kar N, Chan K. Efficacy of antidepressants in treating the negative symptoms of chornic schizophrenia: meta-analysis. Br J Psychiatry 2010;197(3):174-179.
    • (2010) Br J Psychiatry , vol.197 , Issue.3 , pp. 174-179
    • Singh, S.P.1    Singh, V.2    Kar, N.3    Chan, K.4
  • 17
    • 73949137552 scopus 로고    scopus 로고
    • The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements
    • Buchanan RW, Kreyenbuhl J, Kelly DL, Noel JM, Boggs DL, Fischer BA, et al. The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements. Schizophr Bull 2010;36(1):71-93.
    • (2010) Schizophr Bull , vol.36 , Issue.1 , pp. 71-93
    • Buchanan, R.W.1    Kreyenbuhl, J.2    Kelly, D.L.3    Noel, J.M.4    Boggs, D.L.5    Fischer, B.A.6
  • 18
    • 80053330201 scopus 로고    scopus 로고
    • Adjunct mirtazapine for negative symptoms of schizophrenia
    • Phan SV, Kreys TJ. Adjunct mirtazapine for negative symptoms of schizophrenia. Pharmacotherapy 2011;31(10):1017-1030.
    • (2011) Pharmacotherapy , vol.31 , Issue.10 , pp. 1017-1030
    • Phan, S.V.1    Kreys, T.J.2
  • 19
    • 77956569105 scopus 로고    scopus 로고
    • More evidence on additive antipsychotic effect of adjunctive mirtazapine in schizophrenia: An extension phase of a randomized controlled trial
    • Terevnikov V, Stenberf JH, Joffe M, Tiihonen J, Burkin M, Tchoukhine E, et al. More evidence on additive antipsychotic effect of adjunctive mirtazapine in schizophrenia: an extension phase of a randomized controlled trial. Human Psychopharmacol 2010;25(6):431-438.
    • (2010) Human Psychopharmacol , vol.25 , Issue.6 , pp. 431-438
    • Terevnikov, V.1    Stenberf, J.H.2    Joffe, M.3    Tiihonen, J.4    Burkin, M.5    Tchoukhine, E.6
  • 21
    • 1542286227 scopus 로고    scopus 로고
    • The effect of mirtazapine augmentation of clozapine in the treatment of negative symptoms of schizophrenia: A double-blind, placebo-controlled study
    • Zoccali R, Muscatello MR, Cedro C, Neri P, La Torre D, Spina E, et al. The effect of mirtazapine augmentation of clozapine in the treatment of negative symptoms of schizophrenia: a double-blind, placebo-controlled study. Int Clin Psychopharmacol 2004;19(2):71-76.
    • (2004) Int Clin Psychopharmacol , vol.19 , Issue.2 , pp. 71-76
    • Zoccali, R.1    Muscatello, M.R.2    Cedro, C.3    Neri, P.4    La Torre, D.5    Spina, E.6
  • 22
    • 77953540588 scopus 로고    scopus 로고
    • Effects of add-on mirtazapine on neurocognition in schizophrenia: A double-blind, randomized, placebo-controlled study
    • Stenberg JH, Terevnikov V, Joffe M, Tiihonen J, Tchoukhine E, Burkin M, et al. Effects of add-on mirtazapine on neurocognition in schizophrenia: a double-blind, randomized, placebo-controlled study. Int J Neuropsychopharmacol 2010;13(4):433-441.
    • (2010) Int J Neuropsychopharmacol , vol.13 , Issue.4 , pp. 433-441
    • Stenberg, J.H.1    Terevnikov, V.2    Joffe, M.3    Tiihonen, J.4    Tchoukhine, E.5    Burkin, M.6
  • 23
    • 78650943515 scopus 로고    scopus 로고
    • Mirtazapine augmentation enhances cognitive and reduces negative symptoms in schizophrenia patients treated with risperidone: A randomized controlled trial
    • Cho SJ, Yook K, Kim B, Choi TK, Lee KS, Kim YW, et al. Mirtazapine augmentation enhances cognitive and reduces negative symptoms in schizophrenia patients treated with risperidone: a randomized controlled trial. Prog Neuropsychopharmacol Biol Psychiatry 2011;35(1):208-211.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , Issue.1 , pp. 208-211
    • Cho, S.J.1    Yook, K.2    Kim, B.3    Choi, T.K.4    Lee, K.S.5    Kim, Y.W.6
  • 24
    • 74449083580 scopus 로고    scopus 로고
    • The effect of mirtazapine add on therapy to risperidone in the treatment of schizophrenia: A double-blind randomized placebo-controlled trial
    • Abbasi SH, Behpournia H, Ghoreshi A, Salehi B, Raznahan M, Rezazadeh SA, et al. The effect of mirtazapine add on therapy to risperidone in the treatment of schizophrenia: a double-blind randomized placebo-controlled trial. Schizophr Res 2010;116(2-3):101-106.
    • (2010) Schizophr Res , vol.116 , Issue.2-3 , pp. 101-106
    • Abbasi, S.H.1    Behpournia, H.2    Ghoreshi, A.3    Salehi, B.4    Raznahan, M.5    Rezazadeh, S.A.6
  • 25
    • 67649723855 scopus 로고    scopus 로고
    • Mirtazapine add-on therapy in the treatment of schizophrenia with atypical antipsychotics: A double-blind, randomised, placebo-controlled clinical trial
    • Berk M, Gama CS, Sundram S, Hustig H, Koopowitz L, D'Souza R, et al. Mirtazapine add-on therapy in the treatment of schizophrenia with atypical antipsychotics: a double-blind, randomised, placebo-controlled clinical trial. Hum Psychopharmacol 2009;24(3):233-238.
    • (2009) Hum Psychopharmacol , vol.24 , Issue.3 , pp. 233-238
    • Berk, M.1    Gama, C.S.2    Sundram, S.3    Hustig, H.4    Koopowitz, L.5    D'Souza, R.6
  • 26
    • 60249102800 scopus 로고    scopus 로고
    • Add-on mirtazapine enhances antipsychotic effect of first generation antipsychotics in schizophrenia: A double-blind, randomized, placebo-controlled trial
    • Joffe G, Terevnikov V, Joffe M, Stenberg JH, Burkin M, Tiihonen J. Add-on mirtazapine enhances antipsychotic effect of first generation antipsychotics in schizophrenia: a double-blind, randomized, placebo-controlled trial. Schizophr Res 2009;108(1-3):245-251.
    • (2009) Schizophr Res , vol.108 , Issue.1-3 , pp. 245-251
    • Joffe, G.1    Terevnikov, V.2    Joffe, M.3    Stenberg, J.H.4    Burkin, M.5    Tiihonen, J.6
  • 27
    • 0035116237 scopus 로고    scopus 로고
    • Efficacy of mirtazapine add on therapy to haloperidol in the treatment of the negative symptoms of schizophrenia: A double-blind randomized placebo-controlled study
    • Berk M, Ichim C, Brook S. Efficacy of mirtazapine add on therapy to haloperidol in the treatment of the negative symptoms of schizophrenia: a double-blind randomized placebo-controlled study. Int Clin Psychopharmacol 2001;16(2):87-92.
    • (2001) Int Clin Psychopharmacol , vol.16 , Issue.2 , pp. 87-92
    • Berk, M.1    Ichim, C.2    Brook, S.3
  • 28
    • 0034082008 scopus 로고    scopus 로고
    • Differential efficacy of olanzapine for deficit and nondeficit negative symptoms in schizophrenia
    • Kopelowicz A, Zarate R, Tripodis K, Gonzalez V, Mintz J. Differential efficacy of olanzapine for deficit and nondeficit negative symptoms in schizophrenia. Am J Psychiatry 2000;157(6):987-993.
    • (2000) Am J Psychiatry , vol.157 , Issue.6 , pp. 987-993
    • Kopelowicz, A.1    Zarate, R.2    Tripodis, K.3    Gonzalez, V.4    Mintz, J.5
  • 30
    • 79955063321 scopus 로고    scopus 로고
    • Mirtazapine in combination with perospirone synergistically enhances dopamine release in the rat prefrontal cortex via 5-HT1A receptor activation
    • Morita M, Nakayama K. Mirtazapine in combination with perospirone synergistically enhances dopamine release in the rat prefrontal cortex via 5-HT1A receptor activation. Psychiatry Clin Neurosci 2011;65(3):246-253.
    • (2011) Psychiatry Clin Neurosci , vol.65 , Issue.3 , pp. 246-253
    • Morita, M.1    Nakayama, K.2
  • 32
    • 0024321406 scopus 로고
    • Cholinergic hyperactivity and negative schizophrenic symptoms. A model of cholinergic/dopaminergic interactions in schizophrenia
    • Tandon R, Greden JF. Cholinergic hyperactivity and negative schizophrenic symptoms. A model of cholinergic/dopaminergic interactions in schizophrenia. Arch Gen Psychiatry 1989;46(8):745-753.
    • (1989) Arch Gen Psychiatry , vol.46 , Issue.8 , pp. 745-753
    • Tandon, R.1    Greden, J.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.