-
1
-
-
4143141823
-
The immunobiology of cancer immunosurveillance and immunoediting
-
Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity. 2004;21:137-148.
-
(2004)
Immunity.
, vol.21
, pp. 137-148
-
-
Dunn, G.P.1
Old, L.J.2
Schreiber, R.D.3
-
2
-
-
84880706152
-
Oncology meets immunology: The cancer-immunity cycle
-
Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013;39:1-10.
-
(2013)
Immunity.
, vol.39
, pp. 1-10
-
-
Chen, D.S.1
Mellman, I.2
-
3
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012;12: 252-264.
-
(2012)
Nat Rev Cancer.
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
4
-
-
84255197842
-
Cancer immunotherapy comes of age
-
Mellman I, Coukos G, Dranoff G. Cancer immunotherapy comes of age. Nature. 2011;480:480-489.
-
(2011)
Nature.
, vol.480
, pp. 480-489
-
-
Mellman, I.1
Coukos, G.2
Dranoff, G.3
-
5
-
-
52449102477
-
Long-term survival for patients with non-small-cell lung cancer with intratumoral lymphoid structures
-
Dieu-Nosjean M-C, Antoine M, Danel C, et al. Long-term survival for patients with non-small-cell lung cancer with intratumoral lymphoid structures. J Clin Oncol. 2008;26:4410-4417.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 4410-4417
-
-
Dieu-Nosjean, M.-C.1
Antoine, M.2
Danel, C.3
-
6
-
-
84897391372
-
Presence of B cells in tertiary lymphoid structures is associated with a protective immunity in patients with lung cancer
-
Germain C, Gnjatic S, Tamzalit F, et al. Presence of B cells in tertiary lymphoid structures is associated with a protective immunity in patients with lung cancer. Am J Respir Crit Care Med. 2014;189:832-844.
-
(2014)
Am J Respir Crit Care Med.
, vol.189
, pp. 832-844
-
-
Germain, C.1
Gnjatic, S.2
Tamzalit, F.3
-
7
-
-
33846465547
-
Immunos-timulatory monoclonal antibodies for cancer therapy
-
Melero I, Hervas-Stubbs S, Glennie M, et al. Immunos-timulatory monoclonal antibodies for cancer therapy. Nat Rev Cancer. 2007;7:95-106.
-
(2007)
Nat Rev Cancer.
, vol.7
, pp. 95-106
-
-
Melero, I.1
Hervas-Stubbs, S.2
Glennie, M.3
-
8
-
-
65349119978
-
CD28 and CTLA-4 coreceptor expression and signal transduction
-
Rudd CE, Taylor A, Schneider H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol Rev. 2009;229:12-26.
-
(2009)
Immunol Rev.
, vol.229
, pp. 12-26
-
-
Rudd, C.E.1
Taylor, A.2
Schneider, H.3
-
9
-
-
0042470540
-
Does the immune system see tumors as foreign or self?
-
Pardoll D. Does the immune system see tumors as foreign or self? Annu Rev Immunol. 2003;21:807-839.
-
(2003)
Annu Rev Immunol.
, vol.21
, pp. 807-839
-
-
Pardoll, D.1
-
10
-
-
84923197176
-
Immune escape mechanisms as a guide for cancer immunotherapy
-
Beatty GL, Gladney WL. Immune escape mechanisms as a guide for cancer immunotherapy. Clin Cancer Res. 2015;21:687-692.
-
(2015)
Clin Cancer Res.
, vol.21
, pp. 687-692
-
-
Beatty, G.L.1
Gladney, W.L.2
-
11
-
-
84863594742
-
Cellular constituents of immune escape within the tumor microenvironment
-
Kerkar SP, Restifo NP. Cellular constituents of immune escape within the tumor microenvironment. Cancer Res. 2012;72:3125-3130.
-
(2012)
Cancer Res.
, vol.72
, pp. 3125-3130
-
-
Kerkar, S.P.1
Restifo, N.P.2
-
12
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014;515: 563-567.
-
(2014)
Nature.
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
-
13
-
-
84904024273
-
Association of PD-1 PD-1 ligands and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
-
Taube JM, Klein A, Brahmer JR, et al. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res. 2014;20:5064-5074.
-
(2014)
Clin Cancer Res.
, vol.20
, pp. 5064-5074
-
-
Taube, J.M.1
Klein, A.2
Brahmer, J.R.3
-
14
-
-
84960080350
-
Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: A potential issue for anti-PD-L1 therapeutic strategies
-
Ilie M, Long-Mira E, Bence C, et al. Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies. Ann Oncol. 2016;27:147-153.
-
(2016)
Ann Oncol.
, vol.27
, pp. 147-153
-
-
Ilie, M.1
Long-Mira, E.2
Bence, C.3
-
15
-
-
85010777933
-
Quantitative assessment of the heterogeneity of PD-L1 expression in non-small-cell lung cancer
-
McLaughlin J, Han G, Schalper KA, et al. Quantitative assessment of the heterogeneity of PD-L1 expression in non-small-cell lung cancer. JAMA Oncol. 2016;2:46-54.
-
(2016)
JAMA Oncol.
, vol.2
, pp. 46-54
-
-
McLaughlin, J.1
Han, G.2
Schalper, K.A.3
-
16
-
-
84926678589
-
PD-L1 expression in melanoma shows marked heterogeneity within and between patients: Implications for anti-PD-1/PD-L1 clinical trials
-
Madore J, Vilain RE, Menzies AM, et al. PD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trials. Pigment Cell Melanoma Res. 2015;28: 245-253.
-
(2015)
Pigment Cell Melanoma Res.
, vol.28
, pp. 245-253
-
-
Madore, J.1
Vilain, R.E.2
Menzies, A.M.3
-
17
-
-
84937629331
-
PD-L1 expression and tumor-infiltrating lymphocytes define different subsets of MAPK inhibitor-treated melanoma patients
-
Kakavand H, Wilmott JS, Menzies AM, et al. PD-L1 expression and tumor-infiltrating lymphocytes define different subsets of MAPK inhibitor-treated melanoma patients. Clin Cancer Res. 2015;21:3140-3148.
-
(2015)
Clin Cancer Res.
, vol.21
, pp. 3140-3148
-
-
Kakavand, H.1
Wilmott, J.S.2
Menzies, A.M.3
-
18
-
-
84956607290
-
Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer
-
Sheng J, Fang W, Yu J, et al. Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer. Sci Rep. 2016;6:20090.
-
(2016)
Sci Rep.
, vol.6
, pp. 20090
-
-
Sheng, J.1
Fang, W.2
Yu, J.3
-
19
-
-
84884271914
-
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma
-
Simpson TR, Li F, Montalvo-Ortiz W, et al. Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma. J Exp Med. 2013;210:1695-1710.
-
(2013)
J Exp Med.
, vol.210
, pp. 1695-1710
-
-
Simpson, T.R.1
Li, F.2
Montalvo-Ortiz, W.3
-
20
-
-
84928917822
-
Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma
-
Schadendorf D, Hodi FS, Robert C, et al. Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma. J Clin Oncol. 2015;33:1889-1894.
-
(2015)
J Clin Oncol.
, vol.33
, pp. 1889-1894
-
-
Schadendorf, D.1
Hodi, F.S.2
Robert, C.3
-
21
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366:2443-2454.
-
(2012)
N Engl J Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
22
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013;369:134-144.
-
(2013)
N Engl J Med.
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
-
23
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
Garon EB, Rizvi NA, Hui R, et al. Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med. 2015;372:2018-2028.
-
(2015)
N Engl J Med.
, vol.372
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
-
24
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366:2455-2465.
-
(2012)
N Engl J Med.
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
25
-
-
84951279998
-
Antibody-dependent cellular cytotoxicity activity of a novel anti-PD-L1 antibody avelumab (MSB0010718C) on human tumor cells
-
Boyerinas B, Jochems C, Fantini M, et al. Antibody-dependent cellular cytotoxicity activity of a novel anti-PD-L1 antibody avelumab (MSB0010718C) on human tumor cells. Cancer Immunol Res. 2015;3:1148-1157.
-
(2015)
Cancer Immunol Res.
, vol.3
, pp. 1148-1157
-
-
Boyerinas, B.1
Jochems, C.2
Fantini, M.3
-
26
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013;369:122-133.
-
(2013)
N Engl J Med.
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
27
-
-
84959133719
-
Combination cancer immunotherapies tailored to the tumour microenviron-ment
-
Smyth MJ, Ngiow SF, Ribas A, et al. Combination cancer immunotherapies tailored to the tumour microenviron-ment. Nat Rev Clin Oncol. 2016;13:143-158.
-
(2016)
Nat Rev Clin Oncol.
, vol.13
, pp. 143-158
-
-
Smyth, M.J.1
Ngiow, S.F.2
Ribas, A.3
-
28
-
-
84933678156
-
Adjuvant ipilimumab versus placebo after complete resec-tion of high-risk stage III melanoma (EORTC 18071): A randomised, double-blind, phase 3 trial
-
Eggermont AM, Chiarion-Sileni V, Grob JJ, et al. Adjuvant ipilimumab versus placebo after complete resec-tion of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial. Lancet Oncol. 2015;16:522-530.
-
(2015)
Lancet Oncol.
, vol.16
, pp. 522-530
-
-
Eggermont, A.M.1
Chiarion-Sileni, V.2
Grob, J.J.3
-
29
-
-
84926525215
-
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
-
Twyman-Saint Victor C, Rech AJ, Maity A, et al. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature. 2015;520:373-377.
-
(2015)
Nature.
, vol.520
, pp. 373-377
-
-
Twyman-Saint Victor, C.1
Rech, A.J.2
Maity, A.3
-
31
-
-
84923307798
-
Small cell lung cancer: Where do we go from here?
-
Byers LA, Rudin CM. Small cell lung cancer: where do we go from here? Cancer. 2015;121:664-672.
-
(2015)
Cancer.
, vol.121
, pp. 664-672
-
-
Byers, L.A.1
Rudin, C.M.2
-
32
-
-
70649099227
-
Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: Disappointing results
-
Oze I, Hotta K, Kiura K, et al. Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results. PLoS One. 2009;4:e7835.
-
(2009)
PLoS One.
, vol.4
, pp. e7835
-
-
Oze, I.1
Hotta, K.2
Kiura, K.3
-
33
-
-
84941986957
-
Small cell lung cancer: Will recent progress lead to improved outcomes?
-
Pietanza MC, Byers LA, Minna JD, Rudin CM. Small cell lung cancer: will recent progress lead to improved outcomes? Clin Cancer Res. 2015;21:2244-2255.
-
(2015)
Clin Cancer Res.
, vol.21
, pp. 2244-2255
-
-
Pietanza, M.C.1
Byers, L.A.2
Minna, J.D.3
Rudin, C.M.4
-
34
-
-
84964580823
-
A DLL3-targeted adc, rovalpituzumab tesirine, demonstrates substantial activity in a phase i study in relapsed and refractory SCLC
-
Rudin CM, Pietanza MC, Spigel DR, et al. A DLL3-targeted adc, rovalpituzumab tesirine, demonstrates substantial activity in a phase I study in relapsed and refractory SCLC. J Thorac Oncol. 2015;10(suppl 2): S192 S193.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. S192-S193
-
-
Rudin, C.M.1
Pietanza, M.C.2
Spigel, D.R.3
-
35
-
-
84876412243
-
Rationale for chemotherapy, immunotherapy, and checkpoint blockade in SCLC: Beyond traditional treatment approaches
-
Spigel DR, Socinski MA. Rationale for chemotherapy, immunotherapy, and checkpoint blockade in SCLC: beyond traditional treatment approaches. J Thorac Oncol. 2013;8:587 598.
-
(2013)
J Thorac Oncol.
, vol.8
, Issue.587
, pp. 598
-
-
Spigel, D.R.1
Socinski, M.A.2
-
36
-
-
84946592868
-
Plasticity beyond cancer cells and the "immunosuppressive switch"
-
Granot Z, Fridlender ZG. Plasticity beyond cancer cells and the "immunosuppressive switch" Cancer Res. 2015;75:4441-4445.
-
(2015)
Cancer Res.
, vol.75
, pp. 4441-4445
-
-
Granot, Z.1
Fridlender, Z.G.2
-
37
-
-
84884151496
-
Tumor associated macrophages and neutrophils in cancer
-
Galdiero MR, Bonavita E, Barajon I, et al. Tumor associated macrophages and neutrophils in cancer. Immunobiology. 2013;218:1402-1410.
-
(2013)
Immunobiology.
, vol.218
, pp. 1402-1410
-
-
Galdiero, M.R.1
Bonavita, E.2
Barajon, I.3
-
38
-
-
84925872136
-
Tumor-infiltrating dendritic cells in cancer pathogenesis
-
Tran Janco JM, Lamichhane P, Karyampudi L, et al. Tumor-infiltrating dendritic cells in cancer pathogenesis. J Immunol. 2015;194:2985 2991.
-
(2015)
J Immunol.
, vol.194
, Issue.2985
, pp. 2991
-
-
Tran Janco, J.M.1
Lamichhane, P.2
Karyampudi, L.3
-
39
-
-
84946541822
-
Paving the road to tumor development and spreading: Myeloid-derived suppressor cells are ruling the fate
-
Meirow Y, Kanterman J, Baniyash M. Paving the road to tumor development and spreading: myeloid-derived suppressor cells are ruling the fate. Front Immunol. 2015;6:523.
-
(2015)
Front Immunol.
, vol.6
, pp. 523
-
-
Meirow, Y.1
Kanterman, J.2
Baniyash, M.3
-
40
-
-
84944392614
-
Regulatory B cell: New member of immunosuppressive cell club
-
Ding T, Yan F, Cao S, et al. Regulatory B cell: new member of immunosuppressive cell club. Hum Immunol. 2015;76:615 621.
-
(2015)
Hum Immunol.
, vol.76
, Issue.615
, pp. 621
-
-
Ding, T.1
Yan, F.2
Cao, S.3
-
41
-
-
84923686879
-
The interplay of effector and regulatory T cells in cancer
-
Roychoudhuri R, Eil RL, Restifo NP. The interplay of effector and regulatory T cells in cancer. Curr Opin Immunol. 2015;33:101-111.
-
(2015)
Curr Opin Immunol.
, vol.33
, pp. 101-111
-
-
Roychoudhuri, R.1
Eil, R.L.2
Restifo, N.P.3
-
42
-
-
84885468442
-
Inactivation of tumor-specific CD8∗CTLs by tumor-infiltrating tolerogenic dendritic cells
-
Harimoto H, Shimizu M, Nakagawa Y, et al. Inactivation of tumor-specific CD8∗CTLs by tumor-infiltrating tolerogenic dendritic cells. Immunol Cell Biol. 2013;91:545-555.
-
(2013)
Immunol Cell Biol.
, vol.91
, pp. 545-555
-
-
Harimoto, H.1
Shimizu, M.2
Nakagawa, Y.3
-
43
-
-
84946552670
-
Critical role of tumor microenvironment in shaping NK cell functions: Implication of hypoxic stress
-
Hasmim M, Messai Y, Ziani L, et al. Critical role of tumor microenvironment in shaping NK cell functions: implication of hypoxic stress. Front Immunol. 2015;6:482.
-
(2015)
Front Immunol.
, vol.6
, pp. 482
-
-
Hasmim, M.1
Messai, Y.2
Ziani, L.3
-
44
-
-
84901008789
-
Control of the immune response by pro- A ngiogenic factors
-
Voron T, Marcheteau E, Pernot S, et al. Control of the immune response by pro- A ngiogenic factors. Front Oncol. 2014;4:70.
-
(2014)
Front Oncol.
, vol.4
, pp. 70
-
-
Voron, T.1
Marcheteau, E.2
Pernot, S.3
-
45
-
-
84867902940
-
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
-
Huang Y, Yuan J, Righi E, et al. Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proc Natl Acad Sci USA. 2012;109:17561 17566.
-
(2012)
Proc Natl Acad Sci USA.
, vol.109
, pp. 17561-17566
-
-
Huang, Y.1
Yuan, J.2
Righi, E.3
-
46
-
-
84877870613
-
Vascular normalization as an emerging strategy to enhance cancer immunotherapy
-
Huang Y, Goel S, Duda DG, et al. Vascular normalization as an emerging strategy to enhance cancer immunotherapy. Cancer Res. 2013;73:2943 2948.
-
(2013)
Cancer Res.
, vol.73
, Issue.2943
, pp. 2948
-
-
Huang, Y.1
Goel, S.2
Duda, D.G.3
-
47
-
-
0034124299
-
A high number of tumor-infiltrating lymphocytes are associated with a small tumor size, low tumor stage, and a favorable prognosis in operated small cell lung carcinoma
-
Eerola AK, Soini Y, Pääkkö P. A high number of tumor-infiltrating lymphocytes are associated with a small tumor size, low tumor stage, and a favorable prognosis in operated small cell lung carcinoma. Clin Cancer Res. 2000;6:1875 1881.
-
(2000)
Clin Cancer Res.
, vol.6
, Issue.1875
, pp. 1881
-
-
Eerola, A.K.1
Soini, Y.2
Pääkkö, P.3
-
48
-
-
84871966745
-
Histologic assessment of tumor- A ssociated CD45(+) cell numbers is an independent predictor of prognosis in small cell lung cancer
-
Wang W, Hodkinson P, McLaren F, et al. Histologic assessment of tumor- A ssociated CD45(+) cell numbers is an independent predictor of prognosis in small cell lung cancer. Chest. 2013;143:146-151.
-
(2013)
Chest.
, vol.143
, pp. 146-151
-
-
Wang, W.1
Hodkinson, P.2
McLaren, F.3
-
49
-
-
84864130225
-
Small cell lung cancer tumour cells induce regulatory T lymphocytes, and patient survival correlates negatively with FOXP3+ cells in tumour infiltrate
-
Wang W, Hodkinson P, McLaren F. Small cell lung cancer tumour cells induce regulatory T lymphocytes, and patient survival correlates negatively with FOXP3+ cells in tumour infiltrate. Int J Cancer. 2012;131:E928-E937.
-
(2012)
Int J Cancer.
, vol.131
, pp. E928-E937
-
-
Wang, W.1
Hodkinson, P.2
McLaren, F.3
-
50
-
-
58149234402
-
Reciprocal CD4+ T-cell balance of effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ regulatory T cells in small cell lung cancer reflects disease stage
-
Koyama K, Kagamu H, Miura S, et al. Reciprocal CD4+ T-cell balance of effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ regulatory T cells in small cell lung cancer reflects disease stage. Clin Cancer Res. 2008;14:6770-6779.
-
(2008)
Clin Cancer Res.
, vol.14
, pp. 6770-6779
-
-
Koyama, K.1
Kagamu, H.2
Miura, S.3
-
51
-
-
0028270578
-
Peripheral blood lymphocyte subsets and survival in small-cell lung cancer
-
Studnicka M, Wirnsberger R, Neumann M, et al. Peripheral blood lymphocyte subsets and survival in small-cell lung cancer. Chest. 1994;105:1673-1678.
-
(1994)
Chest.
, vol.105
, pp. 1673-1678
-
-
Studnicka, M.1
Wirnsberger, R.2
Neumann, M.3
-
52
-
-
84864022729
-
Increased numbers but functional defects of CD56+CD3+ cells in lung cancer
-
Al Omar SY, Marshall E, Middleton D, et al. Increased numbers but functional defects of CD56+CD3+ cells in lung cancer. Int Immunol. 2012;24:409-415.
-
(2012)
Int Immunol.
, vol.24
, pp. 409-415
-
-
Al Omar, S.Y.1
Marshall, E.2
Middleton, D.3
-
53
-
-
77949266099
-
CD8+CD28-cells and CD4+CD25+ regulatory Tcells in the peripheral blood of advanced stage lung cancer patients
-
Karagöz B, Bilgi O, Gümüs M, et al. CD8+CD28-cells and CD4+CD25+ regulatory Tcells in the peripheral blood of advanced stage lung cancer patients. Med Oncol. 2010;27:29-33.
-
(2010)
Med Oncol.
, vol.27
, pp. 29-33
-
-
Karagöz, B.1
Bilgi, O.2
Gümüs, M.3
-
54
-
-
84918828514
-
Genetic basis for clinical response to CTLA-4 blockade in melanoma
-
Snyder A, Makarov V, Merghoub T, et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med. 2014;371:2189-2199.
-
(2014)
N Engl J Med.
, vol.371
, pp. 2189-2199
-
-
Snyder, A.1
Makarov, V.2
Merghoub, T.3
-
55
-
-
84943516465
-
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
-
Van Allen EM, Miao D, Schilling B, et al. Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science. 2015;350:207-211.
-
(2015)
Science.
, vol.350
, pp. 207-211
-
-
Van Allen, E.M.1
Miao, D.2
Schilling, B.3
-
56
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
Le DT, Uram JN, Wang H, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015;372:2509-2520.
-
(2015)
N Engl J Med.
, vol.372
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
-
57
-
-
84928761118
-
Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
Rizvi NA, Hellmann MD, Snyder A, et al. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science. 2015;348:124-128.
-
(2015)
Science.
, vol.348
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
-
58
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher TN, Schreiber RD. Neoantigens in cancer immunotherapy. Science. 2015;348:69-74.
-
(2015)
Science.
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
59
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, et al. Signatures of mutational processes in human cancer. Nature. 2013;500:415-421.
-
(2013)
Nature.
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
-
61
-
-
40749109846
-
Paraneoplastic syndromes of the CNS
-
Dalmau J, Rosenfeld MR. Paraneoplastic syndromes of the CNS. Lancet Neurol. 2008;7:327-340.
-
(2008)
Lancet Neurol.
, vol.7
, pp. 327-340
-
-
Dalmau, J.1
Rosenfeld, M.R.2
-
62
-
-
77956383370
-
Paraneoplastic syndromes: An approach to diagnosis and treatment
-
Pelosof LC, Gerber DE. Paraneoplastic syndromes: an approach to diagnosis and treatment. Mayo Clin Proc. 2010;85:838-854.
-
(2010)
Mayo Clin Proc.
, vol.85
, pp. 838-854
-
-
Pelosof, L.C.1
Gerber, D.E.2
-
63
-
-
0030792989
-
Anti-Hu antibodies in patients with small-cell lung cancer: Association with complete response to therapy and improved survival
-
Graus F, Dalmou J, Reñé R, et al. Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival. J Clin Oncol. 1997;15:2866-2872.
-
(1997)
J Clin Oncol.
, vol.15
, pp. 2866-2872
-
-
Graus, F.1
Dalmou, J.2
Reñé, R.3
-
64
-
-
35649005489
-
Neurological course of long-term surviving patients with SCLC and anti-Hu syndrome
-
Poepel A, Jarius S, Heukamp LC, et al. Neurological course of long-term surviving patients with SCLC and anti-Hu syndrome. J Neurol Sci. 2007;263:145-148.
-
(2007)
J Neurol Sci.
, vol.263
, pp. 145-148
-
-
Poepel, A.1
Jarius, S.2
Heukamp, L.C.3
-
65
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non small-cell lung cancer
-
Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus docetaxel in advanced nonsquamous non small-cell lung cancer. N Engl J Med. 2015;373:1627-1639.
-
(2015)
N Engl J Med.
, vol.373
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
-
66
-
-
84942867600
-
Programmed death-ligand 1 immunohistochemistry in lung cancer: In what state is this art?
-
Kerr KM, Tsao MS, Nicholson AG, et al. Programmed death-ligand 1 immunohistochemistry in lung cancer: in what state is this art? J Thorac Oncol. 2015;10: 985-989.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. 985-989
-
-
Kerr, K.M.1
Tsao, M.S.2
Nicholson, A.G.3
-
67
-
-
84926421308
-
Significance of programmed cell death-ligand 1 expression and its as-sociation with survival in patients with small cell lung cancer
-
Ishii H, Azuma K, Kawahara A, et al. Significance of programmed cell death-ligand 1 expression and its as-sociation with survival in patients with small cell lung cancer. J Thorac Oncol. 2015;10:426-430.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. 426-430
-
-
Ishii, H.1
Azuma, K.2
Kawahara, A.3
-
68
-
-
84938743950
-
PD-L1 expression in small cell lung cancer
-
Komiya T, Madan R. PD-L1 expression in small cell lung cancer. Eur J Cancer. 2015;51:1853 1855.
-
(2015)
Eur J Cancer.
, vol.51
, Issue.1853
, pp. 1855
-
-
Komiya, T.1
Madan, R.2
-
69
-
-
84922502823
-
PD-L1 expression in small cell neuroendocrine carcinomas
-
Schultheis AM, Scheel AH, Ozretic L, et al. PD-L1 expression in small cell neuroendocrine carcinomas. Eur J Cancer. 2015;51:421-426.
-
(2015)
Eur J Cancer.
, vol.51
, pp. 421-426
-
-
Schultheis, A.M.1
Scheel, A.H.2
Ozretic, L.3
-
70
-
-
85030372059
-
Association of expression of PD-L1 with the tumor immune microenvironment in small cell lung cancer
-
Yu H, Badzio A, Boyle TA, et al. Association of expression of PD-L1 with the tumor immune microenvironment in small cell lung cancer. J Thorac Oncol. 2015;10 (suppl 2):S222 S223.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. S222-S223
-
-
Yu, H.1
Badzio, A.2
Boyle, T.A.3
-
71
-
-
85006224689
-
Programmed cell death protein 1 and programmed death-ligand 1 are expressed on the surface of some small-cell lung cancer lines
-
Yamane H, Isozaki H, Takeyama M, et al. Programmed cell death protein 1 and programmed death-ligand 1 are expressed on the surface of some small-cell lung cancer lines. Am J Cancer Res. 2015;5: 1553-1557.
-
(2015)
Am J Cancer Res.
, vol.5
, pp. 1553-1557
-
-
Yamane, H.1
Isozaki, H.2
Takeyama, M.3
-
72
-
-
84957426059
-
Predictive biomarkers for programmed death-1/programmed death ligand immune checkpoint inhibitors in non small cell lung cancer
-
Remon J, Chaput N, Planchard D. Predictive biomarkers for programmed death-1/programmed death ligand immune checkpoint inhibitors in non small cell lung cancer. Curr Opin Oncol. 2016;28:122 129.
-
(2016)
Curr Opin Oncol.
, vol.28
, Issue.122
, pp. 129
-
-
Remon, J.1
Chaput, N.2
Planchard, D.3
-
73
-
-
84871532643
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: Results from a randomized, double-blind, multicenter phase 2 trial
-
Reck M, Bondarenko I, Luft A, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial. Ann Oncol. 2013;24:75-83.
-
(2013)
Ann Oncol.
, vol.24
, pp. 75-83
-
-
Reck, M.1
Bondarenko, I.2
Luft, A.3
-
74
-
-
84962289972
-
A novel phase II trial of ipilimumab, carboplatin and etoposide (ICE) for the first line treatment of extensive stage small cell lung cancer (SCLC)
-
Ottensmeier CHH, Galea I, Cross N, et al. A novel phase II trial of ipilimumab, carboplatin and etoposide (ICE) for the first line treatment of extensive stage small cell lung cancer (SCLC). Ann Oncol. 2014;25 (suppl 4):iv511-iv516.
-
(2014)
Ann Oncol.
, vol.25
, pp. iv511-iv516
-
-
Chh, O.1
Galea, I.2
Cross, N.3
-
75
-
-
84964580830
-
Pembrolizumab for ED SCLC: Efficacy and relationship with PD-L1 expression
-
Ott PA, Elez E, Hiret S, et al. Pembrolizumab for ED SCLC: efficacy and relationship with PD-L1 expression. J Thorac Oncol. 2015;10(suppl 2):S193.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. S193
-
-
Ott, P.A.1
Elez, E.2
Hiret, S.3
-
76
-
-
84986880621
-
Nivolumab monotherapy or in combination with ipilimumab for treatment of recurrent small cell lung cancer (SCLC)
-
Calvo E, López-Martin JA, Bendell J, et al. Nivolumab monotherapy or in combination with ipilimumab for treatment of recurrent small cell lung cancer (SCLC). Eur J Cancer. 2015;5(suppl 3):S633.
-
(2015)
Eur J Cancer.
, vol.5
, pp. S633
-
-
Calvo, E.1
López-Martin, J.A.2
Bendell, J.3
-
77
-
-
84939518267
-
Phase I/II study of nivolumab with or without ipilimumab for treatment of recurrent small cell lung cancer (SCLC): CA209-032
-
Antonia SJ, Bendell J, Taylor M, et al. Phase I/II study of nivolumab with or without ipilimumab for treatment of recurrent small cell lung cancer (SCLC): CA209-032. J Clin Oncol. 2015;33(suppl):7503.
-
(2015)
J Clin Oncol.
, vol.33
, pp. 7503
-
-
Antonia, S.J.1
Bendell, J.2
Taylor, M.3
-
78
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
-
Wolchok JD, Hoos A, O'Day S, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009;15:7412-7420.
-
(2009)
Clin Cancer Res.
, vol.15
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O'Day, S.3
-
79
-
-
84863911486
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-celllung cancer: Results from a randomized, double-blind, multicenter phase II study
-
Lynch TJ, Bondarenko I, Luft A, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-celllung cancer: results from a randomized, double-blind, multicenter phase II study. J Clin Oncol. 2012;30:2046-2054.
-
(2012)
J Clin Oncol.
, vol.30
, pp. 2046-2054
-
-
Lynch, T.J.1
Bondarenko, I.2
Luft, A.3
-
80
-
-
84995953435
-
-
U.S. National Institutes of Health. ClinicalTrials.gov Accessed March 31, 2016
-
U.S. National Institutes of Health. ClinicalTrials.gov. https://clinicaltrials.gov/ct2/home. Accessed March 31, 2016.
-
-
-
-
81
-
-
84893362995
-
Incorporating immune-checkpoint inhibitors into systemic therapy of NSCLC
-
Champiat S, Ileana E, Giaccone G, et al. Incorporating immune-checkpoint inhibitors into systemic therapy of NSCLC. J Thorac Oncol. 2014;9:144-153.
-
(2014)
J Thorac Oncol.
, vol.9
, pp. 144-153
-
-
Champiat, S.1
Ileana, E.2
Giaccone, G.3
-
82
-
-
84860520670
-
Modulation of inflammatory immune reactions by low-dose ionizing radia-tion: Molecular mechanisms and clinical application
-
Rödel F, Frey B, Gaipl U, et al. Modulation of inflammatory immune reactions by low-dose ionizing radia-tion: molecular mechanisms and clinical application. Curr Med Chem. 2012;19:1741-1750.
-
(2012)
Curr Med Chem.
, vol.19
, pp. 1741-1750
-
-
Rödel, F.1
Frey, B.2
Gaipl, U.3
-
83
-
-
84925852186
-
CD8+CD103+tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients
-
Djenidi F, Adam J, Goubar A, et al. CD8+CD103+tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients. J Immunol. 2015;194: 3475-3486.
-
(2015)
J Immunol.
, vol.194
, pp. 3475-3486
-
-
Djenidi, F.1
Adam, J.2
Goubar, A.3
-
84
-
-
84860589522
-
Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas
-
Travis WD. Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas. Mod Pathol. 2012;25 (suppl 1):S18-S30.
-
(2012)
Mod Pathol.
, vol.25
, pp. S18-S30
-
-
Travis, W.D.1
-
85
-
-
0026741321
-
Latent period for malignant mesothelioma of occupational origin
-
Lanphear BP, Buncher CR. Latent period for malignant mesothelioma of occupational origin. J Occup Med. 1992;34:718-721.
-
(1992)
J Occup Med.
, vol.34
, pp. 718-721
-
-
Lanphear, B.P.1
Buncher, C.R.2
-
86
-
-
26444458845
-
Advances in malignant meso-thelioma
-
Robinson BW, Lake RA. Advances in malignant meso-thelioma. N Engl J Med. 2005;353:1591-1603.
-
(2005)
N Engl J Med.
, vol.353
, pp. 1591-1603
-
-
Robinson, B.W.1
Lake, R.A.2
-
88
-
-
84942416855
-
Survival patterns in lung and pleural cancer in Europe 1999-2007: Results from the EUROCARE-5 study [E-pub ahead of print]
-
accessed July 12, 2016
-
Francisci S, Minicozzi P, Pierannunzio D, et al. Survival patterns in lung and pleural cancer in Europe 1999-2007: results from the EUROCARE-5 study [E-pub ahead of print]. Eur J Cancer. http://dx.doi.org/10.1016/j. ejca.2015.07.033, accessed July 12, 2016.
-
Eur J Cancer
-
-
Francisci, S.1
Minicozzi, P.2
Pierannunzio, D.3
-
89
-
-
84951085442
-
Bevacizumab for newly diagnosed pleural mesothelioma in the Me-sothelioma Avastin Cisplatin Pemetrexed Study (MAPS): A randomised, controlled, open-label, phase 3 trial
-
Zalcman G, Mazieres J, Margery J, et al. Bevacizumab for newly diagnosed pleural mesothelioma in the Me-sothelioma Avastin Cisplatin Pemetrexed Study (MAPS): a randomised, controlled, open-label, phase 3 trial. Lancet. 2016;387:1405-1414.
-
(2016)
Lancet.
, vol.387
, pp. 1405-1414
-
-
Zalcman, G.1
Mazieres, J.2
Margery, J.3
-
90
-
-
84941660341
-
Immunity, inflammation, and cancer: An eternal fight between good and evil
-
Shalapour S, Karin M. Immunity, inflammation, and cancer: an eternal fight between good and evil. J Clin Invest. 2015;125:3347-3355.
-
(2015)
J Clin Invest.
, vol.125
, pp. 3347-3355
-
-
Shalapour, S.1
Karin, M.2
-
91
-
-
84875133954
-
New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas
-
Mossman BT, Shukla A, Heintz NH, et al. New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas. Am J Pathol. 2013;182:1065-1077.
-
(2013)
Am J Pathol.
, vol.182
, pp. 1065-1077
-
-
Mossman, B.T.1
Shukla, A.2
Heintz, N.H.3
-
92
-
-
84948716649
-
Complexity in the tumour microenvironment: Cancer associated fibroblast gene expression patterns identify both common and unique features of tumour-stroma crosstalk across cancer types
-
Gandellini P, Andriani F, Merlino G, et al. Complexity in the tumour microenvironment: Cancer associated fibroblast gene expression patterns identify both common and unique features of tumour-stroma crosstalk across cancer types. Semin Cancer Biol. 2015;35:96-106.
-
(2015)
Semin Cancer Biol.
, vol.35
, pp. 96-106
-
-
Gandellini, P.1
Andriani, F.2
Merlino, G.3
-
93
-
-
84995890745
-
T-cell inflamed phenotype and PDL1 expression in malignant mesothe-lioma [abstract]
-
5s
-
Kindler HL, Zuo Z, Khattri A, et al. T-cell inflamed phenotype and PDL1 expression in malignant mesothe-lioma [abstract]. J Clin Oncol. 2014;32:5s(suppl):7589.
-
(2014)
J Clin Oncol.
, vol.32
, pp. 7589
-
-
Kindler, H.L.1
Zuo, Z.2
Khattri, A.3
-
94
-
-
84995905249
-
Immune escape correlates with an inflamed phenotype in malignant mesothelioma [abstract]
-
Khattri A, Zuo Z, Husain AN, et al. Immune escape correlates with an inflamed phenotype in malignant mesothelioma [abstract]. J Clin Oncol. 2015;33 (suppl):7566.
-
(2015)
J Clin Oncol.
, vol.33
, pp. 7566
-
-
Khattri, A.1
Zuo, Z.2
Husain, A.N.3
-
95
-
-
84944458839
-
The tumoral and stromal immune microenvironment in malignant pleural mesothelioma: A comprehensive analysis reveals prognostic immune markers
-
Ujiie H, Kadota K, Nitadori JI, et al. The tumoral and stromal immune microenvironment in malignant pleural mesothelioma: A comprehensive analysis reveals prognostic immune markers. Oncoimmunology. 2015;4:e1009285.
-
(2015)
Oncoimmunology.
, vol.4
, pp. e1009285
-
-
Ujiie, H.1
Kadota, K.2
Nitadori, J.I.3
-
96
-
-
84925004185
-
Analysis of expression of programmed cell death 1 ligand 1 (PD-L1) in malignant pleural mesothelioma (MPM)
-
Cedrés S, Ponce-Aix S, Zugazagoitia J, et al. Analysis of expression of programmed cell death 1 ligand 1 (PD-L1) in malignant pleural mesothelioma (MPM). PLoS One. 2015;10:e0121071.
-
(2015)
PLoS One.
, vol.10
, pp. e0121071
-
-
Cedrés, S.1
Ponce-Aix, S.2
Zugazagoitia, J.3
-
97
-
-
84902522051
-
B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis
-
Mansfield AS, Roden AC, Peikert T, et al. B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis. J Thorac Oncol. 2014;9:1036-1040.
-
(2014)
J Thorac Oncol.
, vol.9
, pp. 1036-1040
-
-
Mansfield, A.S.1
Roden, A.C.2
Peikert, T.3
-
98
-
-
84962129362
-
Immune biomarkers PD-1/PD-L1 and TLR3 in malignant pleural mesotheliomas
-
Combaz-Lair C, Galateau-Sallé F, McLeer-Florin A, et al. Immune biomarkers PD-1/PD-L1 and TLR3 in malignant pleural mesotheliomas. Hum Pathol. 2016;52:9-18.
-
(2016)
Hum Pathol.
, vol.52
, pp. 9-18
-
-
Combaz-Lair, C.1
Galateau-Sallé, F.2
McLeer-Florin, A.3
-
99
-
-
84884703526
-
Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: An open-label, single- A rm, phase 2 trial
-
Calabrò L, Morra A, Fonsatti E, et al. Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single- A rm, phase 2 trial. Lancet Oncol. 2013;14:1104-1111.
-
(2013)
Lancet Oncol.
, vol.14
, pp. 1104-1111
-
-
Calabrò, L.1
Morra, A.2
Fonsatti, E.3
-
100
-
-
84926418972
-
Efficacy and safety of an intensified schedule of tremelimumab for chemotherapy-resistant malignant mesothelioma: An open-label, single- A rm, phase 2 study
-
Calabrò L, Morra A, Fonsatti E, et al. Efficacy and safety of an intensified schedule of tremelimumab for chemotherapy-resistant malignant mesothelioma: an open-label, single- A rm, phase 2 study. Lancet Respir Med. 2015;3:301-309.
-
(2015)
Lancet Respir Med.
, vol.3
, pp. 301-309
-
-
Calabrò, L.1
Morra, A.2
Fonsatti, E.3
-
101
-
-
1342267614
-
Modified RECIST criteria for assessment of response in malignant pleural mesothe-lioma
-
Byrne MJ, Nowak AK. Modified RECIST criteria for assessment of response in malignant pleural mesothe-lioma. Ann Oncol. 2004;15:257-260.
-
(2004)
Ann Oncol.
, vol.15
, pp. 257-260
-
-
Byrne, M.J.1
Nowak, A.K.2
-
102
-
-
84995890752
-
-
AstraZeneca. AstraZeneca reports top-line result of trem-elimumab monotherapy trial in mesothelioma Accessed July 12, 2016
-
AstraZeneca. AstraZeneca reports top-line result of trem-elimumab monotherapy trial in mesothelioma. https://www.astrazeneca.com/our-company/media-centre/press-releases/2016/astrazeneca-reports-top-line-result-of-tremelimumab-monotherapy-trial-in-mesothelioma-29022 016.html. Accessed July 12, 2016.
-
-
-
-
103
-
-
84975179144
-
Clinical safety and efficacy of pembrolizumab (MK-3475) in patients with malignant pleural mesothelioma: Preliminary results from KEYNOTE-028
-
Alley EW, Molife LR, Santoro A, et al. Clinical safety and efficacy of pembrolizumab (MK-3475) in patients with malignant pleural mesothelioma: Preliminary results from KEYNOTE-028. Cancer Res. 2015;75:CT103.
-
(2015)
Cancer Res.
, vol.75
, pp. CT103
-
-
Alley, E.W.1
Molife, L.R.2
Santoro, A.3
-
104
-
-
84975231262
-
Single- A Gent pembrolizumab for patients with malignant pleural mesothelioma (MPM)
-
Alley EW, Schellens JHM, Santoro A, et al. Single- A gent pembrolizumab for patients with malignant pleural mesothelioma (MPM). J Thorac Oncol. 2015;10(suppl 2):S195.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. S195
-
-
Alley, E.W.1
Jhm, S.2
Santoro, A.3
-
105
-
-
85030371583
-
Safety and clinical activity of avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with advanced, unresectable mesothelioma: A phase Ib trial
-
Hassan R, Thomas A, Patel MR, et al. Safety and clinical activity of avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with advanced, unresectable mesothelioma: a phase Ib trial. Eur J Cancer. 2015;51 (suppl 3):S639.
-
(2015)
Eur J Cancer.
, vol.51
, pp. S639
-
-
Hassan, R.1
Thomas, A.2
Patel, M.R.3
-
107
-
-
84953874197
-
Radiation and checkpoint blockade immunotherapy: Radio-sensitisation and potential mechanisms of synergy
-
Sharabi AB, Lim M, DeWeese TL, et al. Radiation and checkpoint blockade immunotherapy: radio-sensitisation and potential mechanisms of synergy. Lancet Oncol. 2015;16:e498-e509.
-
(2015)
Lancet Oncol.
, vol.16
, pp. e498-e509
-
-
Sharabi, A.B.1
Lim, M.2
DeWeese, T.L.3
-
108
-
-
84929145540
-
Immune checkpoint inhibitors in melanoma provide the cornerstones for curative therapies
-
Eggermont AM, Maio M, Robert C. Immune checkpoint inhibitors in melanoma provide the cornerstones for curative therapies. Semin Oncol. 2015;42:429-435.
-
(2015)
Semin Oncol.
, vol.42
, pp. 429-435
-
-
Eggermont, A.M.1
Maio, M.2
Robert, C.3
-
109
-
-
84948467165
-
Nuclear FAK controls chemokine transcription Tregs and evasion of anti-tumor immunity
-
Serrels A, Lund T, Serrels B, et al. Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity. Cell. 2015;163:160-173.
-
(2015)
Cell.
, vol.163
, pp. 160-173
-
-
Serrels, A.1
Lund, T.2
Serrels, B.3
-
110
-
-
84928062583
-
Immune checkpoint blockade: A common denominator approach to cancer therapy
-
Topalian SL, Drake CG, Pardoll DM. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell. 2015;27:450-461.
-
(2015)
Cancer Cell.
, vol.27
, pp. 450-461
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
111
-
-
33947223664
-
Prospect of targeting the CD40 pathway for cancer therapy
-
Vonderheide RH. Prospect of targeting the CD40 pathway for cancer therapy. Clin Cancer Res. 2007;13: 1083-1088.
-
(2007)
Clin Cancer Res.
, vol.13
, pp. 1083-1088
-
-
Vonderheide, R.H.1
-
112
-
-
84924369766
-
The efficacy of tumor debulking surgery is improved by adjuvant immunotherapy using imiquimod and anti-CD40
-
Khong A, Cleaver AL, Fahmi Alatas M, et al. The efficacy of tumor debulking surgery is improved by adjuvant immunotherapy using imiquimod and anti-CD40. BMC Cancer. 2014;14:969.
-
(2014)
BMC Cancer.
, vol.14
, pp. 969
-
-
Khong, A.1
Cleaver, A.L.2
Fahmi Alatas, M.3
-
113
-
-
84949936992
-
A phase 1b clinical trial of the CD40- A ctivating antibody CP-870, 893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma
-
Nowak AK, Cook AM, McDonnell AM, et al. A phase 1b clinical trial of the CD40- A ctivating antibody CP-870, 893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma. Ann Oncol. 2015;26:2483-2490.
-
(2015)
Ann Oncol.
, vol.26
, pp. 2483-2490
-
-
Nowak, A.K.1
Cook, A.M.2
McDonnell, A.M.3
-
114
-
-
84964314846
-
Alterations of the immune system in thymic malignancies
-
Weksler B, Lu B. Alterations of the immune system in thymic malignancies. J Thorac Oncol. 2014;9 (suppl 2):S137-S142.
-
(2014)
J Thorac Oncol.
, vol.9
, pp. S137-S142
-
-
Weksler, B.1
Lu, B.2
-
115
-
-
84962574871
-
Thymic epithelial tumor- A ssociated cytopenia: A 10-year observational study in France
-
Mar
-
Rivoisy C, Besse B, Girard N, et al. Thymic epithelial tumor- A ssociated cytopenia: a 10-year observational study in france. J Thorac Oncol. 2016 Mar;11: 391-399.
-
(2016)
J Thorac Oncol.
, vol.11
, pp. 391-399
-
-
Rivoisy, C.1
Besse, B.2
Girard, N.3
-
116
-
-
84922257471
-
The impact of thymoma histotype on prognosis in a worldwide database
-
Weis CA, Yao X, Deng Y, et al. The impact of thymoma histotype on prognosis in a worldwide database. J Thorac Oncol. 2015;10:367-372.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. 367-372
-
-
Weis, C.A.1
Yao, X.2
Deng, Y.3
-
117
-
-
34347333453
-
Paraneoplastic diseases associated with thymoma
-
Evoli A, Minicuci GM, Vitaliani R, et al. Paraneoplastic diseases associated with thymoma. J Neurol. 2007;254: 756-762.
-
(2007)
J Neurol.
, vol.254
, pp. 756-762
-
-
Evoli, A.1
Minicuci, G.M.2
Vitaliani, R.3
-
118
-
-
84965117190
-
Myasthenia gravis with thymic epithelial tumour: A retrospective analysis of a Japanese database
-
Nakajima J, Okumura M, Yano M, et al. Myasthenia gravis with thymic epithelial tumour: a retrospective analysis of a Japanese database. Eur J Cardiothorac Surg. 2016;49:1510-1515.
-
(2016)
Eur J Cardiothorac Surg.
, vol.49
, pp. 1510-1515
-
-
Nakajima, J.1
Okumura, M.2
Yano, M.3
-
119
-
-
0035496231
-
Lymphostromal interactions in thymic development and function
-
Anderson G, Jenkinson EJ. Lymphostromal interactions in thymic development and function. Nat Rev Immunol. 2001;1:31-40.
-
(2001)
Nat Rev Immunol.
, vol.1
, pp. 31-40
-
-
Anderson, G.1
Jenkinson, E.J.2
-
121
-
-
45249094990
-
Common cellular and diverse genetic basis of thymoma- A ssociated myasthenia gravis: Role of MHC class II and AIRE genes and genetic polymorphisms
-
Ströbel P, Chuang WY, Chuvpilo S, et al. Common cellular and diverse genetic basis of thymoma- A ssociated myasthenia gravis: role of MHC class II and AIRE genes and genetic polymorphisms. Ann N Y Acad Sci. 2008;1132:143-156.
-
(2008)
Ann N y Acad Sci.
, vol.1132
, pp. 143-156
-
-
Ströbel, P.1
Chuang, W.Y.2
Chuvpilo, S.3
-
122
-
-
33947694597
-
Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1)
-
Ströbel P, Murumägi A, Klein R, et al. Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1). J Pathol. 2007;211:563-571.
-
(2007)
J Pathol.
, vol.211
, pp. 563-571
-
-
Ströbel, P.1
Murumägi, A.2
Klein, R.3
-
123
-
-
34547899524
-
Expression of autoimmune regulator gene (AIRE) and T regulatory cells in human thymomas
-
Scarpino S, Di Napoli A, Stoppacciaro A, et al. Expression of autoimmune regulator gene (AIRE) and T regulatory cells in human thymomas. Clin Exp Immunol. 2007;149:504-512.
-
(2007)
Clin Exp Immunol.
, vol.149
, pp. 504-512
-
-
Scarpino, S.1
Di Napoli, A.2
Stoppacciaro, A.3
-
124
-
-
0031779306
-
Abnormal thymocyte development and generation of autoreactive T cells in mixed and cortical thymomas
-
Nenninger R, Schultz A, Hoffacker V, et al. Abnormal thymocyte development and generation of autoreactive T cells in mixed and cortical thymomas. Lab Invest. 1998;78:743-753.
-
(1998)
Lab Invest.
, vol.78
, pp. 743-753
-
-
Nenninger, R.1
Schultz, A.2
Hoffacker, V.3
-
125
-
-
77957583341
-
Thymoma and thymic carcinoma: Molecular pathology and targeted therapy
-
Ströbel P, Hohenberger P, Marx A. Thymoma and thymic carcinoma: molecular pathology and targeted therapy. J Thorac Oncol. 2010;5(suppl 4):S286-S290.
-
(2010)
J Thorac Oncol.
, vol.5
, pp. S286-S290
-
-
Ströbel, P.1
Hohenberger, P.2
Marx, A.3
-
126
-
-
11144354401
-
WHO histo-logic classification is a prognostic indicator in thymoma
-
Kondo K, Yoshizawa K, Tsuyuguchi M, et al. WHO histo-logic classification is a prognostic indicator in thymoma. Ann Thorac Surg. 2004;77:1183-1188.
-
(2004)
Ann Thorac Surg.
, vol.77
, pp. 1183-1188
-
-
Kondo, K.1
Yoshizawa, K.2
Tsuyuguchi, M.3
-
127
-
-
84942513697
-
The 2015 World Health Organization classification of tumors of the thymus: Continuity and changes
-
Marx A, Chan JK, Coindre JM, et al. The 2015 World Health Organization classification of tumors of the thymus: continuity and changes. J Thorac Oncol. 2015;10:1383-1395.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. 1383-1395
-
-
Marx, A.1
Chan, J.K.2
Coindre, J.M.3
-
128
-
-
80053633053
-
Prognostic effect of stromal lymphocyte infiltration in thymic carcinoma
-
Shim HS, Byun CS, Bae MK, et al. Prognostic effect of stromal lymphocyte infiltration in thymic carcinoma. Lung Cancer. 2011;74:338-343.
-
(2011)
Lung Cancer.
, vol.74
, pp. 338-343
-
-
Shim, H.S.1
Byun, C.S.2
Bae, M.K.3
-
129
-
-
0037307930
-
Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
-
Brown JA, Dorfman DM, Ma FR, et al. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J Immunol. 2003;170:1257-1266.
-
(2003)
J Immunol.
, vol.170
, pp. 1257-1266
-
-
Brown, J.A.1
Dorfman, D.M.2
Ma, F.R.3
-
130
-
-
84926420934
-
Diffuse high intensity PD-L1 staining in thymic epithelial tumors
-
Padda SK, Riess JW, Schwartz EJ, et al. Diffuse high intensity PD-L1 staining in thymic epithelial tumors. J Thorac Oncol. 2015;10:500-508.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. 500-508
-
-
Padda, S.K.1
Riess, J.W.2
Schwartz, E.J.3
-
131
-
-
84926419179
-
Immunohisto-chemical status of PD-L1 in thymoma and thymic carcinoma
-
Katsuya Y, Fujita Y, Horinouchi H, et al. Immunohisto-chemical status of PD-L1 in thymoma and thymic carcinoma. Lung Cancer. 2015;88:154-159.
-
(2015)
Lung Cancer.
, vol.88
, pp. 154-159
-
-
Katsuya, Y.1
Fujita, Y.2
Horinouchi, H.3
-
132
-
-
84961217846
-
Clinicopathologic and prognostic implications of Programmed Death Ligand 1 expression in thymoma
-
Yokoyama S, Miyoshi H, Nishi T, et al. Clinicopathologic and prognostic implications of Programmed Death Ligand 1 expression in thymoma. Ann Thorac Surg. 2016;101:1361-1369.
-
(2016)
Ann Thorac Surg.
, vol.101
, pp. 1361-1369
-
-
Yokoyama, S.1
Miyoshi, H.2
Nishi, T.3
-
133
-
-
84962438570
-
The clini-copathological significance of PD-L1 expression in thymoma
-
Takumi Y, Osoegawa A, Hashimoto T, et al. The clini-copathological significance of PD-L1 expression in thymoma. J Thorac Oncol. 2015;10(suppl 2):S510-S511.
-
(2015)
J Thorac Oncol.
, vol.10
, pp. S510-S511
-
-
Takumi, Y.1
Osoegawa, A.2
Hashimoto, T.3
-
134
-
-
84962386194
-
Defining the immu-nologic phenotype of thymic epithelial tumors [abstract]
-
Naidoo J, Steele K, Sima CS, et al. Defining the immu-nologic phenotype of thymic epithelial tumors [abstract]. J Clin Oncol. 2015;33(suppl):7516.
-
(2015)
J Clin Oncol.
, vol.33
, pp. 7516
-
-
Naidoo, J.1
Steele, K.2
Sima, C.S.3
-
135
-
-
84929077760
-
Available evidence and new biological perspectives on medical treatment of advanced thymic epithelial tumors
-
Serpico D, Trama A, Haspinger ER, et al. Available evidence and new biological perspectives on medical treatment of advanced thymic epithelial tumors. Ann Oncol. 2015;26:838-847.
-
(2015)
Ann Oncol.
, vol.26
, pp. 838-847
-
-
Serpico, D.1
Trama, A.2
Haspinger, E.R.3
-
136
-
-
84921841165
-
Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: An open-label phase 2 trial
-
Thomas A, Rajan A, Berman A, et al. Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial. Lancet Oncol. 2015;16:177-186.
-
(2015)
Lancet Oncol.
, vol.16
, pp. 177-186
-
-
Thomas, A.1
Rajan, A.2
Berman, A.3
-
137
-
-
84995896486
-
Phase II study of pembrolizumab in patients with recurrent thymic carcinoma
-
March 21-21, 2016; Washington, DC
-
Giaccone G, Thompson J, Crawford J, et al. Phase II study of pembrolizumab in patients with recurrent thymic carcinoma. Presentation O5.5. at the 14th Target Anticancer Therapies Congress. March 21-21, 2016; Washington, DC.
-
Presentation O5.5. at the 14th Target Anticancer Therapies Congress
-
-
Giaccone, G.1
Thompson, J.2
Crawford, J.3
-
138
-
-
84953309212
-
Immune-related adverse events with immune checkpoint blockade: A comprehensive review
-
Michot JM, Bigenwald C, Champiat S, et al. Immune-related adverse events with immune checkpoint blockade: a comprehensive review. Eur J Cancer. 2016;54:139-148.
-
(2016)
Eur J Cancer.
, vol.54
, pp. 139-148
-
-
Michot, J.M.1
Bigenwald, C.2
Champiat, S.3
|