메뉴 건너뛰기




Volumn 10, Issue 10, 2015, Pages 1383-1395

The 2015 world health organization classification of tumors of the thymus continuity and changes

(13)  Marx, Alexander a   Chan, John K C b   Coindre, Jean Michel c   Detterbeck, Frank d   Girard, Nicolas e   Harris, Nancy L f   Jaffe, Elaine S g   Kurrer, Michael O h   Marom, Edith M i   Moreira, Andre L j   Mukai, Kiyoshi k   Orazi, Attilio l   Ströbel, Philipp m  


Author keywords

Adenocarcinoma; Atypical type A thymoma; Carcinoid; Classification; Combined large cell neuroendocrine carcinoma; Combined thymic carcinoma; Computed tomography; Cytology; Dendritic cell tumor; Ectopic tumor; Genetic; Germ cell tumor; Grey zone lymphoma; GTF2I; Histology; Hodgkin lymphoma; Immunohistochemistry; Immunohistology; International Thymic Malignancy Interest Group; Lymphoma; Mediastinal; Mediastinum; Metastasis; Neuroblastoma; Neuroendocrine; NUT carcinoma; Pathology; Positron emission tomography; Primary mediastinal large B cell lymphoma; Sarcoma; Staging; Thymic carcinoma; Thymoma; Thymus; World Health Organization

Indexed keywords

CD20 ANTIGEN; CD5 ANTIGEN; CYTOKERATIN 19; CYTOKERATIN 20; PROTEIN P40; PROTEIN P63; STEM CELL FACTOR RECEPTOR;

EID: 84942513697     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0000000000000654     Document Type: Review
Times cited : (477)

References (91)
  • 4
    • 84895069436 scopus 로고    scopus 로고
    • Corticomedullary differentiation and maturational arrest in thymomas
    • Ströbel P, Hartmann E, Rosenwald A, et al. Corticomedullary differentiation and maturational arrest in thymomas. Histopathology 2014;64:557-566.
    • (2014) Histopathology , vol.64 , pp. 557-566
    • Ströbel, P.1    Hartmann, E.2    Rosenwald, A.3
  • 5
    • 84895786399 scopus 로고    scopus 로고
    • ITMIG consensus statement on the use of the WHO histological classifcation of thymoma and thymic carcinoma: Refned defnitions, histological criteria, and reporting
    • Marx A, Ströbel P, Badve SS, et al. ITMIG consensus statement on the use of the WHO histological classifcation of thymoma and thymic carcinoma: refned defnitions, histological criteria, and reporting. J Thorac Oncol 2014;9:596-611.
    • (2014) J Thorac Oncol , vol.9 , pp. 596-611
    • Marx, A.1    Ströbel, P.2    Badve, S.S.3
  • 6
    • 84922257471 scopus 로고    scopus 로고
    • The impact of thymoma histotype on prognosis in a worldwide database
    • Weis CA, Yao X, Deng Y, et al.; Contributors to the ITMIG Retrospective Database. The impact of thymoma histotype on prognosis in a worldwide database. J Thorac Oncol 2015;10:367-372.
    • (2015) J Thorac Oncol , vol.10 , pp. 367-372
    • Weis, C.A.1    Yao, X.2    Deng, Y.3
  • 7
    • 84922295451 scopus 로고    scopus 로고
    • Thymic carcinoma outcomes and prognosis: Results of an international analysis
    • 101.e101-102
    • Ahmad U, Yao X, Detterbeck F, et al. Thymic carcinoma outcomes and prognosis: results of an international analysis. J Thorac Cardiovasc Surg 2015;149:95-100, 101.e101-102.
    • (2015) J Thorac Cardiovasc Surg , vol.149 , pp. 95-100
    • Ahmad, U.1    Yao, X.2    Detterbeck, F.3
  • 8
    • 84922284061 scopus 로고    scopus 로고
    • Development of the International Thymic Malignancy Interest Group international database: An unprecedented resource for the study of a rare group of tumors
    • Huang J, Ahmad U, Antonicelli A, et al.; International Thymic Malignancy Interest Group International Database Committee and Contributors. Development of the International Thymic Malignancy Interest Group international database: an unprecedented resource for the study of a rare group of tumors. J Thorac Oncol 2014;9:1573-1578.
    • (2014) J Thorac Oncol , vol.9 , pp. 1573-1578
    • Huang, J.1    Ahmad, U.2    Antonicelli, A.3
  • 9
    • 84922271035 scopus 로고    scopus 로고
    • Outcome of primary neu-roendocrine tumors of the thymus: A joint analysis of the International Thymic Malignancy Interest Group and the European Society of Thoracic Surgeons databases
    • Filosso PL, Ya o X, Ahmad U, et al.; European Society of Thoracic Surgeons Thymic Group Steering Committee. Outcome of primary neu-roendocrine tumors of the thymus: a joint analysis of the International Thymic Malignancy Interest Group and the European Society of Thoracic Surgeons databases. J Thorac Cardiovasc Surg 2015;149:103-109.e2.
    • (2015) J Thorac Cardiovasc Surg , vol.149 , pp. 103e2-103e2
    • Filosso, P.L.1    Yao, X.2    Ahmad, U.3
  • 12
    • 79959817595 scopus 로고    scopus 로고
    • The Masaoka-Koga stage classifcation for thymic malignancies: Classifcation and defnition of terms
    • Detterbeck FC, Nicholson AG, Kondo K, Van Schil P, Moran C. The Masaoka-Koga stage classifcation for thymic malignancies: classifcation and defnition of terms. J Thorac Oncol 2011;6(7 Suppl 3):S1710-1716.
    • (2011) J Thorac Oncol , vol.6 , Issue.7 , pp. S1710-1716
    • Detterbeck, F.C.1    Nicholson, A.G.2    Kondo, K.3    Van Schil, P.4    Moran, C.5
  • 13
  • 15
  • 16
    • 84938293501 scopus 로고    scopus 로고
    • Modifed Masaoka stage and size are independent prognostic predictors in thymoma and modifed Masaoka stage is superior to histopathologic classifcations
    • Roden AC, Yi ES, Jenkins SM, et al. Modifed Masaoka stage and size are independent prognostic predictors in thymoma and modifed Masaoka stage is superior to histopathologic classifcations. J Thorac Oncol 2015;10:691-700.
    • (2015) J Thorac Oncol , vol.10 , pp. 691-700
    • Roden, A.C.1    Yi, E.S.2    Jenkins, S.M.3
  • 17
    • 44249107050 scopus 로고    scopus 로고
    • Histologic classifcation of thymoma: The World Health Organization and beyond
    • Suster S, Moran CA. Histologic classifcation of thymoma: the World Health Organization and beyond. Hematol Oncol Clin North Am 2008;22:381-392.
    • (2008) Hematol Oncol Clin North Am , vol.22 , pp. 381-392
    • Suster, S.1    Moran, C.A.2
  • 18
    • 33646839773 scopus 로고    scopus 로고
    • Clinical value of the WHO classifcation system of thy-moma
    • Detterbeck FC. Clinical value of the WHO classifcation system of thy-moma. Ann Thorac Surg 2006;81:2328-2334.
    • (2006) Ann Thorac Surg , vol.81 , pp. 2328-2334
    • Detterbeck, F.C.1
  • 19
    • 84859247108 scopus 로고    scopus 로고
    • Thymomas I: A clinicopath-ologic correlation of 250 cases with emphasis on the World Health Organization schema
    • Moran CA, Weissferdt A, Kalhor N, et al. Thymomas I: a clinicopath-ologic correlation of 250 cases with emphasis on the World Health Organization schema. Am J Clin Pathol 2012;137:444-450.
    • (2012) Am J Clin Pathol , vol.137 , pp. 444-450
    • Moran, C.A.1    Weissferdt, A.2    Kalhor, N.3
  • 20
    • 2342510977 scopus 로고    scopus 로고
    • Tumor recurrence and survival in patients treated for thymomas and thymic squamous cell carcinomas: A retrospective analysis
    • Ströbel P, Bauer A, Puppe B, et al. Tumor recurrence and survival in patients treated for thymomas and thymic squamous cell carcinomas: a retrospective analysis. J Clin Oncol 2004;22:1501-1509.
    • (2004) J Clin Oncol , vol.22 , pp. 1501-1509
    • Ströbel, P.1    Bauer, A.2    Puppe, B.3
  • 21
    • 84923286173 scopus 로고    scopus 로고
    • Mutations of epigenetic regulatory genes are common in thymic carcinomas
    • Wang Y, Thomas A, Lau C, et al. Mutations of epigenetic regulatory genes are common in thymic carcinomas. Sci Rep 2014;4:7336.
    • (2014) Sci Rep , vol.4 , pp. 7336
    • Wang, Y.1    Thomas, A.2    Lau, C.3
  • 22
    • 84905577590 scopus 로고    scopus 로고
    • A specifc missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors
    • Petrini I, Meltzer PS, Kim IK, et al. A specifc missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. Nat Genet 2014;46:844-849.
    • (2014) Nat Genet , vol.46 , pp. 844-849
    • Petrini, I.1    Meltzer, P.S.2    Kim, I.K.3
  • 23
    • 72549108625 scopus 로고    scopus 로고
    • Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas
    • Girard N, Shen R, Guo T, et al. Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas. Clin Cancer Res 2009;15:6790-6799.
    • (2009) Clin Cancer Res , vol.15 , pp. 6790-6799
    • Girard, N.1    Shen, R.2    Guo, T.3
  • 24
    • 84877094253 scopus 로고    scopus 로고
    • Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors
    • Petrini I, Wang Y, Zucali PA, et al. Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors. Clin Cancer Res 2013;19:1960-1971.
    • (2013) Clin Cancer Res , vol.19 , pp. 1960-1971
    • Petrini, I.1    Wang, Y.2    Zucali, P.A.3
  • 25
    • 67449090048 scopus 로고    scopus 로고
    • Aberrant DNA methylation in thymic epithelial tumors
    • Chen C, Yin B, Wei Q, et al. Aberrant DNA methylation in thymic epithelial tumors. Cancer Invest 2009;27:582-591.
    • (2009) Cancer Invest , vol.27 , pp. 582-591
    • Chen, C.1    Yin, B.2    Wei, Q.3
  • 26
    • 84892377382 scopus 로고    scopus 로고
    • Anti-apoptotic signature in thymic squamous cell carcinomas-functional relevance of anti-apoptotic BIRC3 expression in the thymic carcinoma cell line 1889c
    • Huang B, Belharazem D, Li L, et al. Anti-apoptotic signature in thymic squamous cell carcinomas-functional relevance of anti-apoptotic BIRC3 expression in the thymic carcinoma cell line 1889c. Front Oncol 2013;3:316.
    • (2013) Front Oncol , vol.3 , pp. 316
    • Huang, B.1    Belharazem, D.2    Li, L.3
  • 27
    • 84964316165 scopus 로고    scopus 로고
    • State of the art of genetic alterations in thy-mic epithelial tumors
    • Rajan A, Girard N, Marx A. State of the art of genetic alterations in thy-mic epithelial tumors. J Thorac Oncol 2014;9(9 Suppl 2):S131-S136.
    • (2014) J Thorac Oncol , vol.9 , Issue.9 , pp. S131-S136
    • Rajan, A.1    Girard, N.2    Marx, A.3
  • 28
    • 84927164071 scopus 로고    scopus 로고
    • Molecular profling and targeted therapy for advanced thoracic malignancies: A biomarker-derived, multi-arm, multihistology phase II basket trial
    • Lopez-Chavez A, Thomas A, Rajan A, et al. Molecular profling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multi-arm, multihistology phase II basket trial. J Clin Oncol 2015;33:1000-1007.
    • (2015) J Clin Oncol , vol.33 , pp. 1000-1007
    • Lopez-Chavez, A.1    Thomas, A.2    Rajan, A.3
  • 29
    • 84921873062 scopus 로고    scopus 로고
    • Sunitinib in thymic carcinoma: Enigmas still unresolved
    • Marx A, Weis CA. Sunitinib in thymic carcinoma: enigmas still unresolved. Lancet Oncol 2015;16:124-125.
    • (2015) Lancet Oncol , vol.16 , pp. 124-125
    • Marx, A.1    Weis, C.A.2
  • 30
    • 84926671440 scopus 로고    scopus 로고
    • Type A and AB thymomas: His-tological features associated with increased stage
    • Green AC, Marx A, Strobel P, et al. Type A and AB thymomas: his-tological features associated with increased stage. Histopathology 2015;66:884-891.
    • (2015) Histopathology , vol.66 , pp. 884-891
    • Green, A.C.1    Marx, A.2    Strobel, P.3
  • 31
    • 34347358583 scopus 로고    scopus 로고
    • Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms
    • Nonaka D, Henley JD, Chiriboga L, et al. Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms. Am J Surg Pathol 2007;31:1038-1044.
    • (2007) Am J Surg Pathol , vol.31 , pp. 1038-1044
    • Nonaka, D.1    Henley, J.D.2    Chiriboga, L.3
  • 32
    • 84881316778 scopus 로고    scopus 로고
    • The role of histology in predicting recurrence of type A thymomas: A clinico-pathologic correlation of 23 cases
    • Vladislav IT, Gokmen-Polar Y, Kesler KA, Loehrer PJ, Sr, Badve S. The role of histology in predicting recurrence of type A thymomas: a clinico-pathologic correlation of 23 cases. Mod Pathol 2013;26:1059-1064.
    • (2013) Mod Pathol , vol.26 , pp. 1059-1064
    • Vladislav, I.T.1    Gokmen-Polar, Y.2    Kesler, K.A.3    Loehrer, P.J.4    Badve, S.5
  • 33
    • 84916896496 scopus 로고    scopus 로고
    • Lung squamous cell carcinomas with basaloid histology represent a specifc molecular entity
    • Brambilla C, Laffaire J, Lantuejoul S, et al. Lung squamous cell carcinomas with basaloid histology represent a specifc molecular entity. Clin Cancer Res 2014;20:5777-5786.
    • (2014) Clin Cancer Res , vol.20 , pp. 5777-5786
    • Brambilla, C.1    Laffaire, J.2    Lantuejoul, S.3
  • 34
    • 68249094405 scopus 로고    scopus 로고
    • Thymic basaloid carcinoma: A clinicopathologic study of 12 cases, with a general discussion of basaloid carcinoma and its relationship with adenoid cystic carcinoma
    • Brown JG, Familiari U, Papotti M, et al. Thymic basaloid carcinoma: a clinicopathologic study of 12 cases, with a general discussion of basaloid carcinoma and its relationship with adenoid cystic carcinoma. Am J Surg Pathol 2009;33:1113-1124.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1113-1124
    • Brown, J.G.1    Familiari, U.2    Papotti, M.3
  • 35
    • 0035148970 scopus 로고    scopus 로고
    • Thymic epithelial tumors can develop along two different pathogenetic pathways
    • Zhou R, Zettl A, Ströbel P, et al. Thymic epithelial tumors can develop along two different pathogenetic pathways. Am J Pathol 2001;159:1853-1860.
    • (2001) Am J Pathol , vol.159 , pp. 1853-1860
    • Zhou, R.1    Zettl, A.2    Ströbel, P.3
  • 36
    • 0037313331 scopus 로고    scopus 로고
    • T(11;19)(q21;p13) translocation in muco-epidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
    • Tonon G, Modi S, Wu L, et al. t(11;19)(q21;p13) translocation in muco-epidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nat Genet 2003;33:208-213.
    • (2003) Nat Genet , vol.33 , pp. 208-213
    • Tonon, G.1    Modi, S.2    Wu, L.3
  • 37
    • 67349263518 scopus 로고    scopus 로고
    • Mammalian mastermind like 2 11q21 gene rearrangement in bronchopulmonary mucoepidermoid carcinoma
    • Achcar Rde O, Nikiforova MN, Dacic S, et al. Mammalian mastermind like 2 11q21 gene rearrangement in bronchopulmonary mucoepidermoid carcinoma. Human pathology 2009;40:854-860.
    • (2009) Human Pathology , vol.40 , pp. 854-860
    • Achcar Rde, O.1    Nikiforova, M.N.2    Dacic, S.3
  • 38
    • 84888057919 scopus 로고    scopus 로고
    • Analysis of MAML2 rearrangement in mucoepidermoid carcinoma of the thymus
    • Roden AC, Erickson-Johnson MR, Yi ES, et al. Analysis of MAML2 rearrangement in mucoepidermoid carcinoma of the thymus. Hum Pathol 2013;44:2799-2805.
    • (2013) Hum Pathol , vol.44 , pp. 2799-2805
    • Roden, A.C.1    Erickson-Johnson, M.R.2    Yi, E.S.3
  • 39
    • 34547641362 scopus 로고    scopus 로고
    • Thymic tumor with adenoid cystic carcinoma like features: A clinicopathologic study of 4 cases
    • Di Tommaso L, Kuhn E, Kurrer M, et al. Thymic tumor with adenoid cystic carcinoma like features: a clinicopathologic study of 4 cases. Am J Surg Pathol 2007;31:1161-1167.
    • (2007) Am J Surg Pathol , vol.31 , pp. 1161-1167
    • Di Tommaso, L.1    Kuhn, E.2    Kurrer, M.3
  • 40
    • 84925944599 scopus 로고    scopus 로고
    • Adenocarcinoma of the thymus, enteric type: Report of 2 cases, and proposal for a novel subtype of thymic carcinoma
    • Moser B, Schiefer AI, Janik S, et al. Adenocarcinoma of the thymus, enteric type: report of 2 cases, and proposal for a novel subtype of thymic carcinoma. Am J Surg Pathol 2015;39:541-548.
    • (2015) Am J Surg Pathol , vol.39 , pp. 541-548
    • Moser, B.1    Schiefer, A.I.2    Janik, S.3
  • 41
    • 84905484015 scopus 로고    scopus 로고
    • NSD3-NUT fusion oncoprotein in NUT midline carcinoma: Implications for a novel oncogenic mechanism
    • French CA, Rahman S, Walsh EM, et al. NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism. Cancer Discov 2014;4:928-941.
    • (2014) Cancer Discov , vol.4 , pp. 928-941
    • French, C.A.1    Rahman, S.2    Walsh, E.M.3
  • 42
    • 84867539506 scopus 로고    scopus 로고
    • Clinicopathologic features and long-term outcomes of NUT midline carcinoma
    • Bauer DE, Mitchell CM, Strait KM, et al. Clinicopathologic features and long-term outcomes of NUT midline carcinoma. Clin Cancer Res 2012;18:5773-5779.
    • (2012) Clin Cancer Res , vol.18 , pp. 5773-5779
    • Bauer, D.E.1    Mitchell, C.M.2    Strait, K.M.3
  • 43
    • 84924352610 scopus 로고    scopus 로고
    • Histologic classifcation of thymoma: A practical guide for routine cases
    • den Bakker MA, Roden AC, Marx A, Marino M. Histologic classifcation of thymoma: a practical guide for routine cases. J Thorac Oncol 2014;9(9 Suppl 2):S125-S130.
    • (2014) J Thorac Oncol , vol.9 , Issue.9 , pp. S125-S130
    • Den Bakker, M.A.1    Roden, A.C.2    Marx, A.3    Marino, M.4
  • 44
    • 84874722920 scopus 로고    scopus 로고
    • Thymic epithelial tumours: From basic principles to individualised treatment strategies
    • Girard N. Thymic epithelial tumours: from basic principles to individualised treatment strategies. Eur Respir Rev 2013;22:75-87.
    • (2013) Eur Respir Rev , vol.22 , pp. 75-87
    • Girard, N.1
  • 45
    • 84921841165 scopus 로고    scopus 로고
    • Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: An open-label phase 2 trial
    • Thomas A, Rajan A, Berman A, et al. Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial. Lancet Oncol 2015;16:177-186.
    • (2015) Lancet Oncol , vol.16 , pp. 177-186
    • Thomas, A.1    Rajan, A.2    Berman, A.3
  • 46
    • 84908689205 scopus 로고    scopus 로고
    • A phase I/II trial of belinostat in combination with cisplatin, doxorubicin, and cyclophosphamide in thymic epithelial tumors: A clinical and translational study
    • Thomas A, Rajan A, Szabo E, et al. A phase I/II trial of belinostat in combination with cisplatin, doxorubicin, and cyclophosphamide in thymic epithelial tumors: a clinical and translational study. Clin Cancer Res 2014;20:5392-5402.
    • (2014) Clin Cancer Res , vol.20 , pp. 5392-5402
    • Thomas, A.1    Rajan, A.2    Szabo, E.3
  • 47
    • 84892991988 scopus 로고    scopus 로고
    • Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: A multicentre, open-label, phase 2 trial
    • Rajan A, Carter CA, Berman A, et al. Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial. Lancet Oncol 2014;15:191-200.
    • (2014) Lancet Oncol , vol.15 , pp. 191-200
    • Rajan, A.1    Carter, C.A.2    Berman, A.3
  • 48
    • 1342332358 scopus 로고    scopus 로고
    • Octreotide alone or with predni-sone in patients with advanced thymoma and thymic carcinoma: An Eastern Cooperative Oncology Group Phase II Trial
    • Loehrer PJ, Sr., Wang W, Johnson DH, Aisner SC, Ettinger DS; Eastern Cooperative Oncology Group Phase II Trial. Octreotide alone or with predni-sone in patients with advanced thymoma and thymic carcinoma: an Eastern Cooperative Oncology Group Phase II Trial. J Clin Oncol 2004;22:293-299.
    • (2004) J Clin Oncol , vol.22 , pp. 293-299
    • Loehrer, P.J.1    Wang, W.2    Johnson, D.H.3    Aisner, S.C.4    Ettinger, D.S.5
  • 49
    • 84894594808 scopus 로고    scopus 로고
    • NUT midline carcinoma
    • French C. NUT midline carcinoma. Nat Rev Cancer 2014;14:149-150.
    • (2014) Nat Rev Cancer , vol.14 , pp. 149-150
    • French, C.1
  • 50
    • 84904403713 scopus 로고    scopus 로고
    • Tumor genetics and survival of thymic neuroendocrine neoplasms: A multi-institutional clinicopathologic study
    • Ströbel P, Zettl A, Shilo K, et al. Tumor genetics and survival of thymic neuroendocrine neoplasms: a multi-institutional clinicopathologic study. Genes Chromosomes Cancer 2014;53:738-749.
    • (2014) Genes Chromosomes Cancer , vol.53 , pp. 738-749
    • Ströbel, P.1    Zettl, A.2    Shilo, K.3
  • 51
    • 84942526016 scopus 로고    scopus 로고
    • Thymic neuroendocrine neoplasms (T-NENs) with CTNNB1 (beta-catenin) gene mutation show components of well-differentiated tumor and poorly-differentiated carcinoma, challenging the concept of secondary high-grade neuroendocrine carcinoma
    • (#1956)
    • Pelosi G, Bimbatti M, Fabbri A, et al. Thymic neuroendocrine neoplasms (T-NENs) with CTNNB1 (beta-catenin) gene mutation show components of well-differentiated tumor and poorly-differentiated carcinoma, challenging the concept of secondary high-grade neuroendocrine carcinoma. Mod Pathol 2015;28 (Suppl 2):487A(#1956).
    • (2015) Mod Pathol , vol.28 , pp. 487A
    • Pelosi, G.1    Bimbatti, M.2    Fabbri, A.3
  • 52
    • 0034100321 scopus 로고    scopus 로고
    • Thymic neuroendocrine carcinomas with combined features ranging from well-differentiated (carcinoid) to small cell carcinoma. A clinicopathologic and immunohistochemical study of 11 cases
    • Moran CA, Suster S. Thymic neuroendocrine carcinomas with combined features ranging from well-differentiated (carcinoid) to small cell carcinoma. A clinicopathologic and immunohistochemical study of 11 cases. Am J Clin Pathol 2000;113:345-350.
    • (2000) Am J Clin Pathol , vol.113 , pp. 345-350
    • Moran, C.A.1    Suster, S.2
  • 53
    • 84889090162 scopus 로고    scopus 로고
    • Comparative immunohis-tochemical analysis of pulmonary and thymic neuroendocrine carcinomas using PAX8 and TTF-1
    • Weissferdt A, Tang X, Wistuba, II, Moran CA. Comparative immunohis-tochemical analysis of pulmonary and thymic neuroendocrine carcinomas using PAX8 and TTF-1. Mod Pathol 2013;26:1554-1560.
    • (2013) Mod Pathol , vol.26 , pp. 1554-1560
    • Weissferdt, A.1    Tang, X.2    Wistuba, I.I.3    Moran, C.A.4
  • 54
    • 42949173880 scopus 로고    scopus 로고
    • Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications
    • de Jong J, Stoop H, Gillis AJ, et al. Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications. J Pathol 2008;215:21-30.
    • (2008) J Pathol , vol.215 , pp. 21-30
    • De Jong, J.1    Stoop, H.2    Gillis, A.J.3
  • 55
    • 0037547198 scopus 로고    scopus 로고
    • POU5F1 (OCT3/4) identifes cells with pluripotent potential in human germ cell tumors
    • Looijenga LH, Stoop H, de Leeuw H P, et al. POU5F1 (OCT3/4) identifes cells with pluripotent potential in human germ cell tumors. Cancer Res 2003;63:2244-2250.
    • (2003) Cancer Res , vol.63 , pp. 2244-2250
    • Looijenga, L.H.1    Stoop, H.2    De Leeuw, H.P.3
  • 57
    • 27144435095 scopus 로고    scopus 로고
    • Expression of TP73L is a helpful diagnostic marker of primary mediasti-nal large B-cell lymphomas
    • Zamo A, Malpeli G, Scarpa A, Doglioni C, Chilosi M, Menestrina F. Expression of TP73L is a helpful diagnostic marker of primary mediasti-nal large B-cell lymphomas. Mod Pathol 2005;18:1448-1453.
    • (2005) Mod Pathol , vol.18 , pp. 1448-1453
    • Zamo, A.1    Malpeli, G.2    Scarpa, A.3    Doglioni, C.4    Chilosi, M.5    Menestrina, F.6
  • 58
    • 34247846174 scopus 로고    scopus 로고
    • Expression of p63 in thymomas and normal thymus
    • Dotto J, Pelosi G, Rosai J. Expression of p63 in thymomas and normal thymus. Am J Clin Pathol 2007;127:415-420.
    • (2007) Am J Clin Pathol , vol.127 , pp. 415-420
    • Dotto, J.1    Pelosi, G.2    Rosai, J.3
  • 59
    • 0041853151 scopus 로고    scopus 로고
    • Constitutive expression of DeltaN-p63alpha isoform in human thymus and thymic epithelial tumours
    • Chilosi M, Zamò A, Brighenti A, et al. Constitutive expression of DeltaN-p63alpha isoform in human thymus and thymic epithelial tumours. Virchows Arch 2003;443:175-183.
    • (2003) Virchows Arch , vol.443 , pp. 175-183
    • Chilosi, M.1    Zamò, A.2    Brighenti, A.3
  • 60
    • 0141672946 scopus 로고    scopus 로고
    • Molecular diagnosis of primary mediastinal B cell lymphoma identifes a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
    • Rosenwald A, Wright G, Leroy K, et al. Molecular diagnosis of primary mediastinal B cell lymphoma identifes a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med 2003;198:851-862.
    • (2003) J Exp Med , vol.198 , pp. 851-862
    • Rosenwald, A.1    Wright, G.2    Leroy, K.3
  • 61
    • 84897530680 scopus 로고    scopus 로고
    • Genomic rearrangements involving programmed death ligands are recurrent in primary mediastinal large B-cell lymphoma
    • Twa DD, Chan FC, Ben-Neriah S, et al. Genomic rearrangements involving programmed death ligands are recurrent in primary mediastinal large B-cell lymphoma. Blood 2014;123:2062-2065.
    • (2014) Blood , vol.123 , pp. 2062-2065
    • Twa, D.D.1    Chan, F.C.2    Ben-Neriah, S.3
  • 62
    • 79952816655 scopus 로고    scopus 로고
    • MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
    • Steidl C, Shah S P, Woolcock B W, et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature 2011;471:377-381.
    • (2011) Nature , vol.471 , pp. 377-381
    • Steidl, C.1    Shah, S.P.2    Woolcock, B.W.3
  • 63
    • 84914695751 scopus 로고    scopus 로고
    • Expression of programmed cell death 1 ligand 2 (PD-L2) is a distinguishing feature of primary medias-tinal (thymic) large B-cell lymphoma and associated with PDCD1LG2 copy gain
    • Shi M, Roemer MG, Chapuy B, et al. Expression of programmed cell death 1 ligand 2 (PD-L2) is a distinguishing feature of primary medias-tinal (thymic) large B-cell lymphoma and associated with PDCD1LG2 copy gain. Am J Surg Pathol 2014;38:1715-1723.
    • (2014) Am J Surg Pathol , vol.38 , pp. 1715-1723
    • Shi, M.1    Roemer, M.G.2    Chapuy, B.3
  • 64
    • 84855919042 scopus 로고    scopus 로고
    • Characterization of chromosomal aberrations in thymic MALT lymphoma
    • Kominato S, Nakayama T, Sato F, et al. Characterization of chromosomal aberrations in thymic MALT lymphoma. Pathol Int 2012;62:93-98.
    • (2012) Pathol Int , vol.62 , pp. 93-98
    • Kominato, S.1    Nakayama, T.2    Sato, F.3
  • 65
    • 80052892884 scopus 로고    scopus 로고
    • Thymic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue: A clini-copathological and genetic analysis of six cases
    • Go H, Cho HJ, Paik JH, et al. Thymic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue: a clini-copathological and genetic analysis of six cases. Leuk Lymphoma 2011;52:2276-2283.
    • (2011) Leuk Lymphoma , vol.52 , pp. 2276-2283
    • Go, H.1    Cho, H.J.2    Paik, J.H.3
  • 66
    • 84885019279 scopus 로고    scopus 로고
    • Absence of terminal deoxynucleo-tidyl transferase expression identifes a subset of high-risk adult T-lymphoblastic leukemia/lymphoma
    • Zhou Y, Fan X, Routbort M, et al. Absence of terminal deoxynucleo-tidyl transferase expression identifes a subset of high-risk adult T-lymphoblastic leukemia/lymphoma. Mod Pathol 2013;26:1338-1345.
    • (2013) Mod Pathol , vol.26 , pp. 1338-1345
    • Zhou, Y.1    Fan, X.2    Routbort, M.3
  • 67
    • 84879149485 scopus 로고    scopus 로고
    • Incidence and prognostic relevance of genetic variations in T-cell lymphoblastic lymphoma in childhood and adolescence
    • Bonn BR, Rohde M, Zimmermann M, et al. Incidence and prognostic relevance of genetic variations in T-cell lymphoblastic lymphoma in childhood and adolescence. Blood 2013;121:3153-3160.
    • (2013) Blood , vol.121 , pp. 3153-3160
    • Bonn, B.R.1    Rohde, M.2    Zimmermann, M.3
  • 68
    • 58749095816 scopus 로고    scopus 로고
    • Early T-cell precursor leukaemia: A subtype of very high-risk acute lymphoblastic leukaemia
    • Coustan-Smith E, Mullighan CG, Onciu M, et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol 2009;10:147-156.
    • (2009) Lancet Oncol , vol.10 , pp. 147-156
    • Coustan-Smith, E.1    Mullighan, C.G.2    Onciu, M.3
  • 69
    • 84863975116 scopus 로고    scopus 로고
    • Clinical impact of NOTCH1 and/or FBXW7 mutations, FLASH deletion, and TCR status in pediatric T-cell lymphoblastic lymphoma
    • Callens C, Baleydier F, Lengline E, et al. Clinical impact of NOTCH1 and/or FBXW7 mutations, FLASH deletion, and TCR status in pediatric T-cell lymphoblastic lymphoma. J Clin Oncol 2012;30:1966-1973.
    • (2012) J Clin Oncol , vol.30 , pp. 1966-1973
    • Callens, C.1    Baleydier, F.2    Lengline, E.3
  • 70
    • 33746158950 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 6q14-q24 is associated with poor outcome in children and adolescents with T-cell lymphoblastic lymphoma
    • Burkhardt B, Bruch J, Zimmermann M, et al. Loss of heterozygosity on chromosome 6q14-q24 is associated with poor outcome in children and adolescents with T-cell lymphoblastic lymphoma. Leukemia 2006;20:1422-1429.
    • (2006) Leukemia , vol.20 , pp. 1422-1429
    • Burkhardt, B.1    Bruch, J.2    Zimmermann, M.3
  • 71
    • 84875334036 scopus 로고    scopus 로고
    • New insights in the biology of Hodgkin lymphoma
    • Küppers R. New insights in the biology of Hodgkin lymphoma. Hematology Am Soc Hematol Educ Program 2012;2012:328-334.
    • (2012) Hematology Am Soc Hematol Educ Program , vol.2012 , pp. 328-334
    • Küppers, R.1
  • 72
    • 84891535219 scopus 로고    scopus 로고
    • Defning characteristics of classical Hodgkin lymphoma microenvironment T-helper cells
    • Greaves P, Clear A, Owen A, et al. Defning characteristics of classical Hodgkin lymphoma microenvironment T-helper cells. Blood 2013;122:2856-2863.
    • (2013) Blood , vol.122 , pp. 2856-2863
    • Greaves, P.1    Clear, A.2    Owen, A.3
  • 73
    • 84868587140 scopus 로고    scopus 로고
    • Gene expression profling of microdis-sected Hodgkin Reed-Sternberg cells correlates with treatment outcome in classical Hodgkin lymphoma
    • Steidl C, Diepstra A, Lee T, et al. Gene expression profling of microdis-sected Hodgkin Reed-Sternberg cells correlates with treatment outcome in classical Hodgkin lymphoma. Blood 2012;120:3530-3540.
    • (2012) Blood , vol.120 , pp. 3530-3540
    • Steidl, C.1    Diepstra, A.2    Lee, T.3
  • 74
    • 77949345555 scopus 로고    scopus 로고
    • Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
    • Steidl C, Lee T, Shah S P, et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med 2010;362:875-885.
    • (2010) N Engl J Med , vol.362 , pp. 875-885
    • Steidl, C.1    Lee, T.2    Shah, S.P.3
  • 75
    • 79953879650 scopus 로고    scopus 로고
    • Methylation profling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma
    • Eberle FC, Rodriguez-Canales J, Wei L, et al. Methylation profling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma. Haematologica 2011;96:558-566.
    • (2011) Haematologica , vol.96 , pp. 558-566
    • Eberle, F.C.1    Rodriguez-Canales, J.2    Wei, L.3
  • 76
    • 82555167094 scopus 로고    scopus 로고
    • Gray zone lymphoma: Chromosomal aberrations with immunophenotypic and clinical correlations
    • Eberle FC, Salaverria I, Steidl C, et al. Gray zone lymphoma: chromosomal aberrations with immunophenotypic and clinical correlations. Mod Pathol 2011;24:1586-1597.
    • (2011) Mod Pathol , vol.24 , pp. 1586-1597
    • Eberle, F.C.1    Salaverria, I.2    Steidl, C.3
  • 77
    • 33749072515 scopus 로고    scopus 로고
    • Relationship between classic Hodgkin lymphoma and overlapping large cell lymphoma investigated by comparative expressed sequence hybridization expression profling
    • Vanhentenrijk V, Vanden Bempt I, Dierickx D, Verhoef G, Wlodarska I, De Wolf-Peeters C. Relationship between classic Hodgkin lymphoma and overlapping large cell lymphoma investigated by comparative expressed sequence hybridization expression profling. J Pathol 2006;210:155-162.
    • (2006) J Pathol , vol.210 , pp. 155-162
    • Vanhentenrijk, V.1    Vanden Bempt, I.2    Dierickx, D.3    Verhoef, G.4    Wlodarska, I.5    De Wolf-Peeters, C.6
  • 78
    • 84928701065 scopus 로고    scopus 로고
    • Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): An open-label, randomised, non-inferiority trial
    • Behringer K, Goergen H, Hitz F, et al.; German Hodgkin Study Group; Swiss Group for Clinical Cancer Research; Arbeitsgemeinschaft Medikamentöse Tumortherapie. Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial. Lancet 2015;385:1418-1427.
    • (2015) Lancet , vol.385 , pp. 1418-1427
    • Behringer, K.1    Goergen, H.2    Hitz, F.3
  • 79
    • 84875962936 scopus 로고    scopus 로고
    • Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma
    • Dunleavy K, Pittaluga S, Maeda LS, et al. Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma. N Engl J Med 2013;368:1408-1416.
    • (2013) N Engl J Med , vol.368 , pp. 1408-1416
    • Dunleavy, K.1    Pittaluga, S.2    Maeda, L.S.3
  • 80
    • 84984870459 scopus 로고    scopus 로고
    • Risk of second malignancies in patients with early-stage classical Hodgkin's lym-phoma treated in a modern era
    • LeMieux MH, Solanki AA, Mahmood U, Chmura SJ, Koshy M. Risk of second malignancies in patients with early-stage classical Hodgkin's lym-phoma treated in a modern era. Cancer Med 2015 4:513-518.
    • (2015) Cancer Med , vol.4 , pp. 513-518
    • LeMieux, M.H.1    Solanki, A.A.2    Mahmood, U.3    Chmura, S.J.4    Koshy, M.5
  • 81
    • 84876498502 scopus 로고    scopus 로고
    • Dramatic effcacy of vemu-rafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation
    • Haroche J, Cohen-Aubart F, Emile JF, et al. Dramatic effcacy of vemu-rafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation. Blood 2013;121:1495-1500.
    • (2013) Blood , vol.121 , pp. 1495-1500
    • Haroche, J.1    Cohen-Aubart, F.2    Emile, J.F.3
  • 82
    • 84908153532 scopus 로고    scopus 로고
    • Thymoma with loss of keratin expression (and giant cells): A potential diagnostic pitfall
    • Adam P, Hakroush S, Hofmann I, Reidenbach S, Marx A, Ströbel P. Thymoma with loss of keratin expression (and giant cells): a potential diagnostic pitfall. Virchows Archiv 2014;465:313-320.
    • (2014) Virchows Archiv , vol.465 , pp. 313-320
    • Adam, P.1    Hakroush, S.2    Hofmann, I.3    Reidenbach, S.4    Marx, A.5    Ströbel, P.6
  • 83
    • 84873096886 scopus 로고    scopus 로고
    • Identifcation of recurrent NAB2-STAT6 gene fusions in solitary fbrous tumor by integra-tive sequencing
    • Robinson DR, Wu YM, Kalyana-Sundaram S, et al. Identifcation of recurrent NAB2-STAT6 gene fusions in solitary fbrous tumor by integra-tive sequencing. Nat Genet 2013;45:180-185.
    • (2013) Nat Genet , vol.45 , pp. 180-185
    • Robinson, D.R.1    Wu, Y.M.2    Kalyana-Sundaram, S.3
  • 84
    • 84869884642 scopus 로고    scopus 로고
    • High frequency of MYC gene amplif-cation is a common feature of radiation-induced sarcomas. Further results from EORTC STBSG TL 01/01
    • Käcker C, Marx A, Mössinger K, et al. High frequency of MYC gene amplif-cation is a common feature of radiation-induced sarcomas. Further results from EORTC STBSG TL 01/01. Genes Chromosomes Cancer 2013;52:93-98.
    • (2013) Genes Chromosomes Cancer , vol.52 , pp. 93-98
    • Käcker, C.1    Marx, A.2    Mössinger, K.3
  • 85
    • 73949155854 scopus 로고    scopus 로고
    • MYC high level gene amplifcation is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema
    • Manner J, Radlwimmer B, Hohenberger P, et al. MYC high level gene amplifcation is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema. Am J Pathol 2010;176:34-39.
    • (2010) Am J Pathol , vol.176 , pp. 34-39
    • Manner, J.1    Radlwimmer, B.2    Hohenberger, P.3
  • 86
    • 84866857954 scopus 로고    scopus 로고
    • Thymic neuroblastoma within a thymic cyst in an adult
    • Ueda Y, Omasa M, Taki T, et al. Thymic neuroblastoma within a thymic cyst in an adult. Case Rep Oncol 2012;5:459-463.
    • (2012) Case Rep Oncol , vol.5 , pp. 459-463
    • Ueda, Y.1    Omasa, M.2    Taki, T.3
  • 88
    • 84922332274 scopus 로고    scopus 로고
    • Detection of human polyomavi-rus 7 in human thymic epithelial tumors
    • Rennspiess D, Pujari S, Keijzers M, et al. Detection of human polyomavi-rus 7 in human thymic epithelial tumors. J Thorac Oncol 2015;10:360-366.
    • (2015) J Thorac Oncol , vol.10 , pp. 360-366
    • Rennspiess, D.1    Pujari, S.2    Keijzers, M.3
  • 89
    • 43049101092 scopus 로고    scopus 로고
    • Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma
    • Ehemann V, Kern MA, Breinig M, et al. Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma. Int J Cancer 2008;122:2719-2725.
    • (2008) Int J Cancer , vol.122 , pp. 2719-2725
    • Ehemann, V.1    Kern, M.A.2    Breinig, M.3
  • 90
    • 84868568119 scopus 로고    scopus 로고
    • Establishment and characterization of a novel cell line derived from human thymoma AB tumor
    • Gökmen-Polar Y, Sanders KL, Goswami C P, et al. Establishment and characterization of a novel cell line derived from human thymoma AB tumor. Lab Invest 2012;92:1564-1573.
    • (2012) Lab Invest , vol.92 , pp. 1564-1573
    • Gökmen-Polar, Y.1    Sanders, K.L.2    Goswami, C.P.3
  • 91
    • 84939427681 scopus 로고    scopus 로고
    • Thymoma related myas-thenia gravis in humans and potential animal models
    • Marx A, Porubsky S, Belharazem D, et al. Thymoma related myas-thenia gravis in humans and potential animal models. Exp Neurol 2015;270:55-65.
    • (2015) Exp Neurol , vol.270 , pp. 55-65
    • Marx, A.1    Porubsky, S.2    Belharazem, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.