-
1
-
-
17144378367
-
Tumours of the thymus: Introduction
-
In. M.D. Travis, E. Brambilla, H.K. Müller-Hermelink. & C.C. Harris, Eds. IARC Press. Lyon.
-
Müller-Hermelink, H.K., P. Engel, et al. 2004. Tumours of the thymus: introduction. In World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Lung, Thymus and Heart. M.D. Travis, E. Brambilla, H.K. Müller-Hermelink & C.C. Harris, Eds 145 151. IARC Press. Lyon.
-
(2004)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Lung, Thymus and Heart.
, pp. 145-151
-
-
Müller-Hermelink, H.K.1
Engel, P.2
-
2
-
-
0032609983
-
From basic immunobiology to the upcoming who-classification of tumors of the thymus. the second conference on biological and clinical aspects of thymic epithelial tumors and related recent developments
-
&
-
Marx, A. & H.K. Muller-Hermelink. 1999. From basic immunobiology to the upcoming who-classification of tumors of the thymus. The second conference on biological and clinical aspects of thymic epithelial tumors and related recent developments. Pathol. Res. Pract. 195 : 515 533.
-
(1999)
Pathol. Res. Pract.
, vol.195
, pp. 515-533
-
-
Marx, A.1
Muller-Hermelink, H.K.2
-
3
-
-
0031771052
-
CD40 ligand and autoantigen are involved in the pathogenesis of low- grade B-cell lymphomas of mucosa-associated lymphoid tissue
-
Greiner, A., C. Knorr, et al. 1998. CD40 ligand and autoantigen are involved in the pathogenesis of low- grade B-cell lymphomas of mucosa-associated lymphoid tissue. Dev. Immunol. 6 : 187 195.
-
(1998)
Dev. Immunol.
, vol.6
, pp. 187-195
-
-
Greiner, A.1
Knorr, C.2
-
4
-
-
0036792519
-
Chromosome 6 suffers frequent and multiple aberrations in thymoma
-
Inoue, M., A. Marx, et al. 2002. Chromosome 6 suffers frequent and multiple aberrations in thymoma. Am. J. Pathol. 161 : 1507 1513.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1507-1513
-
-
Inoue, M.1
Marx, A.2
-
5
-
-
0034551737
-
Thymomas alter the T-cell subset composition in the blood: A potential mechanism for thymoma-associated autoimmune disease
-
Hoffacker, V., A. Schultz, et al. 2000. Thymomas alter the T-cell subset composition in the blood: a potential mechanism for thymoma-associated autoimmune disease. Blood 96 : 3872 3879.
-
(2000)
Blood
, vol.96
, pp. 3872-3879
-
-
Hoffacker, V.1
Schultz, A.2
-
6
-
-
0034957184
-
Mature, long-lived CD4+ and CD8+ t cells are generated by the thymoma in myasthenia gravis
-
Buckley, C., D. Douek, et al. 2001. Mature, long-lived CD4+ and CD8+ t cells are generated by the thymoma in myasthenia gravis. Ann. Neurol. 50 : 64 72.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 64-72
-
-
Buckley, C.1
Douek, D.2
-
7
-
-
0036227429
-
Diversity in MHC class II antigen presentation
-
&
-
Robinson, J.H. & A.A. Delvig. 2002. Diversity in MHC class II antigen presentation. Immunology 105 : 252 262.
-
(2002)
Immunology
, vol.105
, pp. 252-262
-
-
Robinson, J.H.1
Delvig, A.A.2
-
8
-
-
0029835390
-
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
-
Laufer, T.M., J. DeKoning, et al. 1996. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 383 : 81 85.
-
(1996)
Nature
, vol.383
, pp. 81-85
-
-
Laufer, T.M.1
Dekoning, J.2
-
9
-
-
0035660748
-
Evidence for distinct mechanisms in the shaping of the CD4 T cell repertoire in histologically distinct myasthenia gravis-associated thymomas
-
Strobel, P., M. Helmreich, et al. 2001. Evidence for distinct mechanisms in the shaping of the CD4 T cell repertoire in histologically distinct myasthenia gravis-associated thymomas. Dev. Immunol. 8 : 279 290.
-
(2001)
Dev. Immunol.
, vol.8
, pp. 279-290
-
-
Strobel, P.1
Helmreich, M.2
-
10
-
-
0028985957
-
Accumulation of immature CD3-CD4+CD8- single-positive cells that lack CD69 in epithelial cell tumors of the human thymus
-
Takeuchi, Y., Y. Fujii, et al. 1995. Accumulation of immature CD3-CD4+CD8- single-positive cells that lack CD69 in epithelial cell tumors of the human thymus. Cell. Immunol. 161 : 181 187.
-
(1995)
Cell. Immunol.
, vol.161
, pp. 181-187
-
-
Takeuchi, Y.1
Fujii, Y.2
-
11
-
-
0037528761
-
Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells
-
Waldburger, J.M., S. Rossi, et al. 2003. Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells. Blood 101 : 3550 3559.
-
(2003)
Blood
, vol.101
, pp. 3550-3559
-
-
Waldburger, J.M.1
Rossi, S.2
-
12
-
-
0030949011
-
Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA
-
Muhlethaler-Mottet, A., L.A. Otten, et al. 1997. Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA. Embo. J. 16 : 2851 2860.
-
(1997)
Embo. J.
, vol.16
, pp. 2851-2860
-
-
Muhlethaler-Mottet, A.1
Otten, L.A.2
-
13
-
-
0037080190
-
Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III
-
Holling, T.M., N. van der Stoep, et al. 2002. Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III. J. Immunol. 168 : 763 770.
-
(2002)
J. Immunol.
, vol.168
, pp. 763-770
-
-
Holling, T.M.1
Van Der Stoep, N.2
-
14
-
-
0036839169
-
Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: Identification of a novel regulatory region in the 5'-untranslated region and an important role for camp-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes
-
van der Stoep, N., E. Quinten, et al. 2002. Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5'-untranslated region and an important role for camp-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes. J. Immunol. 169 : 5061 5071.
-
(2002)
J. Immunol.
, vol.169
, pp. 5061-5071
-
-
Van Der Stoep, N.1
Quinten, E.2
-
15
-
-
0032908350
-
Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta
-
Piskurich, J.F., M.W. Linhoff, et al. 1999. Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta. Mol. Cell. Biol. 19 : 431 440.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 431-440
-
-
Piskurich, J.F.1
Linhoff, M.W.2
-
16
-
-
0032703084
-
Differential selectivity of CIITA promoter activation by IFN-gamma and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-alpha
-
Nikcevich, K.M., J.F. Piskurich, et al. 1999. Differential selectivity of CIITA promoter activation by IFN-gamma and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-alpha. J. Neuroimmunol. 99 : 195 204.
-
(1999)
J. Neuroimmunol.
, vol.99
, pp. 195-204
-
-
Nikcevich, K.M.1
Piskurich, J.F.2
-
17
-
-
0033590981
-
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
-
Heino, M., P. Peterson, et al. 1999. Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem. Biophys. Res. Commun. 257 : 821 825.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.257
, pp. 821-825
-
-
Heino, M.1
Peterson, P.2
-
18
-
-
0242536432
-
Mutations in the AIRE gene: Effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis- ectodermal dystrophy protein
-
Bjorses, P., M. Halonen, et al. 2000. Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein. Am. J. Hum. Genet. 66 : 378 392.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 378-392
-
-
Bjorses, P.1
Halonen, M.2
-
19
-
-
23844558032
-
The cellular mechanism of AIRE control of T cell tolerance
-
Anderson, M.S., E.S. Venanzi, et al. 2005. The cellular mechanism of AIRE control of T cell tolerance. Immunity 23 : 227 239.
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
-
20
-
-
32944474710
-
Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator
-
Ramsey, C., S. Hassler, et al. 2006. Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator. Eur. J. Immunol. 36 : 305 317.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 305-317
-
-
Ramsey, C.1
Hassler, S.2
-
21
-
-
0034662906
-
Normal thymic architecture and negative selection are associated with aire expression, the gene defective in the autoimmune-polyendocrinopathy- candidiasis-ectodermal dystrophy (APECED)
-
Zuklys, S., G. Balciunaite, et al. 2000. Normal thymic architecture and negative selection are associated with aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J. Immunol. 165 : 1976 1983.
-
(2000)
J. Immunol.
, vol.165
, pp. 1976-1983
-
-
Zuklys, S.1
Balciunaite, G.2
-
22
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
Liston, A., S. Lesage, et al. 2003. Aire regulates negative selection of organ-specific T cells. Nat. Immunol. 4 : 350 354.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
-
23
-
-
0141836774
-
Immunohistochemical analysis of B-cell lymphoma using tissue microarrays identifies particular phenotypic profiles of B-cell lymphomas
-
Zettl, A., S. Meister, et al. 2003. Immunohistochemical analysis of B-cell lymphoma using tissue microarrays identifies particular phenotypic profiles of B-cell lymphomas. Histopathology 43 : 209 219.
-
(2003)
Histopathology
, vol.43
, pp. 209-219
-
-
Zettl, A.1
Meister, S.2
-
24
-
-
0023858019
-
Pathogenesis of myasthenia gravis. Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors
-
Kirchner, T., S. Tzartos, et al. 1988. Pathogenesis of myasthenia gravis. Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors. Am. J. Pathol. 130 : 268 280.
-
(1988)
Am. J. Pathol.
, vol.130
, pp. 268-280
-
-
Kirchner, T.1
Tzartos, S.2
-
25
-
-
0027377043
-
Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer. Computer-assisted image analysis (qic score) vs. Subjective grading (irs)
-
&
-
Remmele, W. & K.H. Schicketanz. 1993. Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer. Computer-assisted image analysis (qic score) vs. Subjective grading (irs). Pathol. Res. Pract. 189 : 862 866.
-
(1993)
Pathol. Res. Pract.
, vol.189
, pp. 862-866
-
-
Remmele, W.1
Schicketanz, K.H.2
-
26
-
-
0033939699
-
RNA and protein expression of the murine autoimmune regulator gene (aire) in normal, RelB-deficient and in NOD mouse
-
Heino, M., P. Peterson, et al. 2000. RNA and protein expression of the murine autoimmune regulator gene (aire) in normal, RelB-deficient and in NOD mouse. Eur. J. Immunol. 30 : 1884 1893.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1884-1893
-
-
Heino, M.1
Peterson, P.2
-
27
-
-
0037742216
-
Correlating genetic aberrations with world health organization-defined histology and stage across the spectrum of thymomas
-
Inoue, M., P. Starostik, et al. 2003. Correlating genetic aberrations with world health organization-defined histology and stage across the spectrum of thymomas. Cancer Res. 63 : 3708 3715.
-
(2003)
Cancer Res.
, vol.63
, pp. 3708-3715
-
-
Inoue, M.1
Starostik, P.2
-
29
-
-
0031590672
-
Quantification of cytokine mrna expression by RT PCR in samples of previously frozen blood
-
Kruse, N., M. Pette, et al. 1997. Quantification of cytokine mrna expression by RT PCR in samples of previously frozen blood. J. Immunol. Methods 210 : 195 203.
-
(1997)
J. Immunol. Methods
, vol.210
, pp. 195-203
-
-
Kruse, N.1
Pette, M.2
-
30
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
-
Frommer, M., L.E. McDonald, et al. 1992. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl. Acad. Sci. U. S. A. 89 : 1827 1831.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
-
31
-
-
0033789216
-
Lack of CIITA expression is central to the absence of antigen presentation functions of trophoblast cells and is caused by methylation of the IFN-gamma inducible promoter (pIV) of CIITA
-
van den Elsen, P.J., N. van der Stoep, et al. 2000. Lack of CIITA expression is central to the absence of antigen presentation functions of trophoblast cells and is caused by methylation of the IFN-gamma inducible promoter (pIV) of CIITA. Hum. Immunol. 61 : 850 862.
-
(2000)
Hum. Immunol.
, vol.61
, pp. 850-862
-
-
Van Den Elsen, P.J.1
Van Der Stoep, N.2
-
32
-
-
0034655297
-
Methylation of class II trans-activator promoter IV: A novel mechanism of MHC class II gene control
-
Morris, A.C., W.E. Spangler, et al. 2000. Methylation of class II trans-activator promoter IV: a novel mechanism of MHC class II gene control. J. Immunol. 164 : 4143 4149.
-
(2000)
J. Immunol.
, vol.164
, pp. 4143-4149
-
-
Morris, A.C.1
Spangler, W.E.2
-
33
-
-
0036274018
-
Kinetics of a gamma interferon response: Expression and assembly of CIITA promoter IV and inhibition by methylation
-
Morris, A.C., G.W. Beresford, et al. 2002. Kinetics of a gamma interferon response: expression and assembly of CIITA promoter IV and inhibition by methylation. Mol. Cell. Biol. 22 : 4781 4791.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4781-4791
-
-
Morris, A.C.1
Beresford, G.W.2
-
34
-
-
0036466853
-
Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines
-
van der Stoep, N., P. Biesta, et al. 2002. Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines. Int. J. Cancer 97 : 501 507.
-
(2002)
Int. J. Cancer
, vol.97
, pp. 501-507
-
-
Van Der Stoep, N.1
Biesta, P.2
-
35
-
-
0027464928
-
Immune response in mice that lack the interferon-gamma receptor
-
Huang, S., W. Hendriks, et al. 1993. Immune response in mice that lack the interferon-gamma receptor. Science 259 : 1742 1745.
-
(1993)
Science
, vol.259
, pp. 1742-1745
-
-
Huang, S.1
Hendriks, W.2
-
36
-
-
0032780361
-
A minimal level of MHC class II expression is sufficient to abrogate autoreactivity
-
de Bont, E.S., C.R. Reilly, et al. 1999. A minimal level of MHC class II expression is sufficient to abrogate autoreactivity. Int. Immunol. 11 : 1295 1306.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1295-1306
-
-
De Bont, E.S.1
Reilly, C.R.2
-
38
-
-
0037222541
-
Self-specific MHC class II-restricted CD4-CD8- T cells that escape deletion and lack regulatory activity
-
&
-
Viret, C. & C.A. Janeway, Jr. 2003. Self-specific MHC class II-restricted CD4-CD8- T cells that escape deletion and lack regulatory activity. J. Immunol. 170 : 201 209.
-
(2003)
J. Immunol.
, vol.170
, pp. 201-209
-
-
Viret, C.1
Janeway Jr., C.A.2
-
39
-
-
0031779306
-
Abnormal thymocyte development and generation of autoreactive T cells in mixed and cortical thymomas
-
Nenninger, R., A. Schultz, et al. 1998. Abnormal thymocyte development and generation of autoreactive T cells in mixed and cortical thymomas. Lab. Invest. 78 : 743 753.
-
(1998)
Lab. Invest.
, vol.78
, pp. 743-753
-
-
Nenninger, R.1
Schultz, A.2
-
40
-
-
0025045510
-
Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells
-
Sommer, N., N. Willcox, et al. 1990. Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells. Ann. Neurol. 28 : 312 319.
-
(1990)
Ann. Neurol.
, vol.28
, pp. 312-319
-
-
Sommer, N.1
Willcox, N.2
-
41
-
-
9644255923
-
Selective loss of regulatory T cells in thymomas
-
Strobel, P., A. Rosenwald, et al. 2004. Selective loss of regulatory T cells in thymomas. Ann. Neurol. 56 : 901 904.
-
(2004)
Ann. Neurol.
, vol.56
, pp. 901-904
-
-
Strobel, P.1
Rosenwald, A.2
-
42
-
-
0036239887
-
Genetic control of MHC class II expression
-
&
-
Ting, J.P. & J. Trowsdale. 2002. Genetic control of MHC class II expression. Cell. 109 : S21 33.
-
(2002)
Cell.
, vol.109
-
-
Ting, J.P.1
Trowsdale, J.2
-
43
-
-
0031906211
-
Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene
-
Piskurich, J.F., Y. Wang, et al. 1998. Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene. J. Immunol. 160 : 233 240.
-
(1998)
J. Immunol.
, vol.160
, pp. 233-240
-
-
Piskurich, J.F.1
Wang, Y.2
-
44
-
-
0042361884
-
Class II transactivator (CIITA) promoter methylation does not correlate with silencing of CIITA transcription in trophoblasts
-
Holtz, R., J.C. Choi, et al. 2003. Class II transactivator (CIITA) promoter methylation does not correlate with silencing of CIITA transcription in trophoblasts. Biol. Reprod. 69 : 915 924.
-
(2003)
Biol. Reprod.
, vol.69
, pp. 915-924
-
-
Holtz, R.1
Choi, J.C.2
-
45
-
-
0033934538
-
Altered T cell development in human thymoma is related to impairment of mhc class II transactivator expression induced by interferon-gamma (IFN-gamma)
-
Kadota, Y., M. Okumura, et al. 2000. Altered T cell development in human thymoma is related to impairment of mhc class II transactivator expression induced by interferon-gamma (IFN-gamma). Clin. Exp. Immunol. 121 : 59 68.
-
(2000)
Clin. Exp. Immunol.
, vol.121
, pp. 59-68
-
-
Kadota, Y.1
Okumura, M.2
-
46
-
-
33947694597
-
Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1)
-
Strobel, P., A. Murumagi, et al. 2007. Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1). J. Pathol. 211 : 563 571.
-
(2007)
J. Pathol.
, vol.211
, pp. 563-571
-
-
Strobel, P.1
Murumagi, A.2
-
47
-
-
34248598295
-
Selection of FOXP3+ regulatory T cells specific for self antigen expressed and presented by AIRE+ medullary thymic epithelial cells
-
Aschenbrenner, K., L.M. D'Cruz, et al. 2007. Selection of FOXP3+ regulatory T cells specific for self antigen expressed and presented by AIRE+ medullary thymic epithelial cells. Nat. Immunol. 8 : 351 358.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 351-358
-
-
Aschenbrenner, K.1
D'Cruz, L.M.2
-
48
-
-
0036659920
-
Paraneoplastic myasthenia gravis correlates with generation of mature naive CD4(+) T cells in thymomas
-
Strobel, P., M. Helmreich, et al. 2002. Paraneoplastic myasthenia gravis correlates with generation of mature naive CD4(+) T cells in thymomas. Blood 100 : 159 166.
-
(2002)
Blood
, vol.100
, pp. 159-166
-
-
Strobel, P.1
Helmreich, M.2
-
49
-
-
25444484922
-
A CTLA4high genotype is associated with myasthenia gravis in thymoma patients
-
Chuang, W., P. Strobel, et al. 2005. A CTLA4high genotype is associated with myasthenia gravis in thymoma patients. Ann. Neurol. 58 : 644 648.
-
(2005)
Ann. Neurol.
, vol.58
, pp. 644-648
-
-
Chuang, W.1
Strobel, P.2
-
50
-
-
0027400726
-
Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
-
Dalton, D.K., S. Pitts-Meek, et al. 1993. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 259 : 1739 1742.
-
(1993)
Science
, vol.259
, pp. 1739-1742
-
-
Dalton, D.K.1
Pitts-Meek, S.2
-
51
-
-
0028984182
-
IFN-gamma receptor-deficient mice are hypersensitive to the anti-CD3-induced cytokine release syndrome and thymocyte apoptosis. Protective role of endogenous nitric oxide
-
Matthys, P., G. Froyen, et al. 1995. IFN-gamma receptor-deficient mice are hypersensitive to the anti-CD3-induced cytokine release syndrome and thymocyte apoptosis. Protective role of endogenous nitric oxide. J. Immunol. 155 : 3823 3829.
-
(1995)
J. Immunol.
, vol.155
, pp. 3823-3829
-
-
Matthys, P.1
Froyen, G.2
|