Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

Science

Volumn 350, Issue 6257, 2015, Pages 207-211

  Van Allen, Eliezer M ^a,b   Miao, Diana ^a,b   Schilling, Bastian ^c,d   Shukla, Sachet A ^a,b   Blank, Christian ^e   Zimmer, Lisa ^c,d   Sucker, Antje ^c,d   Hillen, Uwe ^c,d   Foppen, Marnix H Geukes ^e   Goldinger, Simone M ^f   Utikal, Jochen ^d,g   Hassel, Jessica C ^h   Weide, Benjamin ⁱ   Kaehler, Katharina C ^j   Loquai, Carmen ^k   Mohr, Peter ^l   Gutzmer, Ralf ^m   Dummer, Reinhard ^f   Gabriel, Stacey ^b   Wu, Catherine J ^a,b   Schadendorf, Dirk ^c,d   Garraway, Levi A ^a,b,c   more..

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e NETHERLANDS CANCER INSTITUTE   (Netherlands)

^f UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^g UNIVERSITY OF HEIDELBERG   (Germany)

^h UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

ⁱ UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^j UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^k UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^l Elbe Kliniken   (Germany)

^m HANNOVER MEDICAL SCHOOL   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IPILIMUMAB; TRANSCRIPTOME; HLA ANTIGEN; MONOCLONAL ANTIBODY; PHARMACOLOGICAL BIOMARKER; TUMOR ANTIGEN;

ANTIBODY; COHORT ANALYSIS; CYTOGENETICS; DISEASE RESISTANCE; GENE EXPRESSION; GENOMICS; IMMUNE RESPONSE; IMMUNE SYSTEM; MUTATION; PEPTIDE; TUMOR;

AMINO ACID SEQUENCE; ARTICLE; CORRELATION ANALYSIS; CYTOLYSIS; GENE MUTATION; GENOMICS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; METASTATIC MELANOMA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TREATMENT RESPONSE; TUMOR BIOPSY; TUMOR MICROENVIRONMENT; ADULT; AGED; ANTAGONISTS AND INHIBITORS; CELL CYCLE CHECKPOINT; COHORT ANALYSIS; DRUG EFFECTS; DRUG RESISTANCE; EXOME; FEMALE; GENETICS; IMMUNOLOGY; MALE; MELANOMA; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; SECONDARY; SKIN NEOPLASMS; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BIOMARKERS, PHARMACOLOGICAL; CELL CYCLE CHECKPOINTS; COHORT STUDIES; CTLA-4 ANTIGEN; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, NEOPLASM; EXOME; FEMALE; GENOMICS; HLA ANTIGENS; HUMANS; MALE; MELANOMA; MIDDLE AGED; MUTATION; SKIN NEOPLASMS; TUMOR MICROENVIRONMENT; YOUNG ADULT;

EID: 84943516465     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad0095     Document Type: Article

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