Modulation of inflammatory immune reactions by low-dose ionizing radiation: Molecular mechanisms and clinical application

Current Medicinal Chemistry

Volumn 19, Issue 12, 2012, Pages 1741-1750

  Rodel F ^a   Frey, B ^b   Gaipl, U ^b   Keilholz, L ^c   Fournier, C ^d   Manda, K ^e   Schollnberger H ^f   Hildebrandt, G ^e   Rodel C ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c Clinical Center Bayreuth   (Germany)

^d GSI Helmholtz für Schwerionenforschung ^*  (Germany)

^e UNIVERSITY OF ROSTOCK   (Germany)

^f INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Biphasic dose response; Discontinuous dose dependency; Immune modulation; Inflammation; Ionizing radiation; Low dose radiation therapy

Indexed keywords

DEATH RECEPTOR; DOUBLE STRANDED DNA; EARLY GROWTH RESPONSE FACTOR 1; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; L SELECTIN; LIPOPOLYSACCHARIDE; LYMPHOTOXIN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE B; PROTEIN P50; PROTEIN P52; PROTEIN P53; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; ATAXIA TELANGIECTASIA; BASOPHIL; DENDRITIC CELL; DNA BINDING; EOSINOPHIL; GAMMA IRRADIATION; HUMAN; IMMUNITY; IMMUNOREGULATION; INFLAMMATION; IONIZING RADIATION; LEUKOCYTE ADHERENCE; MOLECULAR MECHANICS; NEUTROPHIL; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMORPHONUCLEAR CELL; RADIATION DOSE; RADIATION EXPOSURE; RADIOSENSITIVITY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; X IRRADIATION;

APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, RADIATION; E-SELECTIN; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MODELS, GENETIC; MODELS, IMMUNOLOGICAL; RADIATION, IONIZING; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84860520670     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712800099866     Document Type: Article

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