Prognostic effect of stromal lymphocyte infiltration in thrymic carcinoma

Lung Cancer

Volumn 74, Issue 2, 2011, Pages 338-343

  Shim, Hyo Sup ^a   Byun, Chun Sung ^b   Bae, Mi Kyung ^b   Lee, Chang Young ^b   Park, In Kyu ^b   Kim, Dae Joon ^b   Chung, Kyung Young ^b   Lee, Jin Gu ^b  

^a Ewha Womans University School of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

CD20+; CD4+; CD8+; Lymphocyte; Thymic carcinoma

Indexed keywords

CD20 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER SURGERY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MALE; PRIORITY JOURNAL; PROGNOSIS; THYMUS CANCER; TUMOR ASSOCIATED LEUKOCYTE;

ADULT; AGED; ANTIGENS, CD; CARCINOMA; CELL COUNT; CELL MOVEMENT; CONNECTIVE TISSUE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; PROGNOSIS; THYMECTOMY; THYMUS NEOPLASMS; TUMOR ESCAPE; TUMOR MICROENVIRONMENT;

EID: 80053633053     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2011.03.008     Document Type: Article

References (25)

1. Wick M.R., Weiland L.H., Scheithauer B.W., Bernatz P.E. Primary thymic carcinomas. Am J Surg Pathol 1982, 6:451-470.
2. Hsu C.P., Chen C.Y., Chen C.L., Lin C.T., Hsu N.Y., Wang J.H., et al. Thymic carcinoma. J Thorac Cardiovasc Surg 1994, 107:615-620.
3. Underwood J.C. Lymphoreticular infiltration in human tumours: prognostic and biological implications: a review. Br J Cancer 1974, 30:538-548.
4. de Visser K.E., Eichten A., Coussens L.M. Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 2006, 6:24-37.
5. O'Garra A., Arai N. The molecular basis of T helper 1 and T helper 2 cell differentiation. Trends Cell Biol 2000, 10:542-550.
6. Gilboa E. The promise of cancer vaccines. Nat Rev Cancer 2004, 4:401-411.
7. Naito Y., Saito K., Shiiba K., Ohuchi A., Saigenji K., Nagura H., et al. CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res 1998, 58:3491-3494.
8. Schumacher K., Haensch W., Roefzaad C., Schlag P.M. Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas. Cancer Res 2001, 61:3932-3936.
9. Fukunaga A., Miyamoto M., Cho Y., Murakami S., Kawarada Y., Oshikiri T., et al. CD8+ tumor infiltrating lymphocytes together with CD4+ tumor-infiltrating lymphocytes and dendritic cells improve the prognosis of patients with pancreatic adenocarcinoma. Pancreas 2004, 28:e26-e31.
10. Al-Shibli K.I., Donnem T., Al-Saad S., Persson M., Bremnes R.M., Busund L.T. Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small lung cancer. Clin Cancer Res 2008, 14(16):5220-5227.
11. Dunn G.P., Bruce A.T., Ikeda H., Old L.J., Schreiber R.D. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol 2002, 3:991-998.
12. Mukai S., Kjaergaard J., Shu S., Plautz G.E. Infiltration of tumors by systemically transferred tumor-reactive T lymphocytes is required for antitumor efficacy. Cancer Res 1999, 59:5245-5249.
13. Costello R.T., Gastaut J.A., Olive D. Tumor escape from immune surveillance. Arch Immunol Ther Exp (Warsz) 1999, 47:83-88.
14. Enarsson K., Lundin B.S., Johnsson E., Brezicka T., Quiding-Jarbrink M. CD4+ CD25 high regulatory T cells reduce T cell transendothelial migration in cancer patients. Eur J Immunol 2007, 37:28291.
15. Wakabayashi O., Yamazaki K., Oizumi S., Hommura F., Kinoshita I., Ogura S., et al. CD4+ T cells in cancer stroma, not CD8+ Tcells in cancer cell nests, are associated with favorable prognosis in human non-small cell lung cancers. Cancer Sci 2003, 94:1003-1009.
16. Blankenstein T. The role of tumor stroma in the interaction between tumor and immune system. Curr Opin Immunol 2005, 17:180-186.
17. Toes R.E., Ossendorp F., Offringa R., Melief C.J. CD4 T cells and their role in antitumor immune responses. J Exp Med 1999, 189:753-756.
18. Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000, 101:455-458.
19. Hiraoka K., Miyamoto M., Cho Y., Suzuoki M., Oshikiri T., Nakakubo Y., et al. Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma. Br J Cancer 2006, 94:275-280.
20. Nakamura H., Saji H., Ogata A., Hosaka M., Hagiwara M., Kawasaki N., et al. Immunologic parameters as significant prognostic factors in lung cancer. Lung Cancer 2002, 37:161-169.
21. Pelletier M.P., Edwardes M.D., Michel R.P., Halwani F., Morin J.E. Prognostic markers in resectable non-small cell lung cancer: a multivariate analysis. Can J Surg 2001, 44:180-188.
22. Bourgeois C., Veiga-Fernandes H., Joret A.M., Rocha B., Tanchot C. CD8 lethargy in the absence of CD4 help. Eur J Immunol 2002, 32:2199-2207.
23. Kurts C., Carbone F.R., Barnden M., Blanas E., Allison J., Heath W.R., et al. CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity. J Exp Med 1997, 186:2057-2062.
24. Bevan M.J. Helping the CD8(+) T-cell response. Nat Rev Immunol 2004, 4:595-602.
25. DiLillo D.J., Yanaba K., Tedder T.F. B cells are required for optimal CD4+ and CD8+ T cell rumor immunity: therapeutic B cell depletion enhances B16 melanoma growth in mice. J Immunol 2010, 184:4006-4016.