메뉴 건너뛰기




Volumn 37, Issue 12, 2016, Pages 1029-1044

All Roads Lead to the miRNome: miRNAs Have a Central Role in the Molecular Pathophysiology of Psychiatric Disorders

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 132; MICRORNA 137; RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 84995748218     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2016.10.004     Document Type: Review
Times cited : (55)

References (125)
  • 1
    • 84959334398 scopus 로고    scopus 로고
    • Molecular biomarkers of depression
    • 1 Gururajan, A., et al. Molecular biomarkers of depression. Neurosci. Biobehav. Rev. 64 (2016), 101–133.
    • (2016) Neurosci. Biobehav. Rev. , vol.64 , pp. 101-133
    • Gururajan, A.1
  • 2
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • 2 Krol, J., et al. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11 (2010), 597–610.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 597-610
    • Krol, J.1
  • 3
    • 84892821162 scopus 로고    scopus 로고
    • Transcriptome-wide discovery of microRNA binding sites in human brain
    • 3 Boudreau, R.L., et al. Transcriptome-wide discovery of microRNA binding sites in human brain. Neuron 81 (2014), 294–305.
    • (2014) Neuron , vol.81 , pp. 294-305
    • Boudreau, R.L.1
  • 4
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • 4 Lee, R.C., et al. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75 (1993), 843–854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1
  • 5
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • 5 Wightman, B., et al. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75 (1993), 855–862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1
  • 6
    • 77958474656 scopus 로고    scopus 로고
    • Functional shifts in insect microRNA evolution
    • 6 Marco, A., et al. Functional shifts in insect microRNA evolution. Genome Biol. Evol. 2 (2010), 686–696.
    • (2010) Genome Biol. Evol. , vol.2 , pp. 686-696
    • Marco, A.1
  • 7
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • 7 Krichevsky, A.M., et al. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9 (2003), 1274–1281.
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1
  • 8
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissue-specific microRNAs from mouse
    • 8 Lagos-Quintana, M., et al. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12 (2002), 735–739.
    • (2002) Curr. Biol. , vol.12 , pp. 735-739
    • Lagos-Quintana, M.1
  • 9
    • 79251577674 scopus 로고    scopus 로고
    • MicroRNA expression profiling of the porcine developing brain
    • 9 Podolska, A., et al. MicroRNA expression profiling of the porcine developing brain. PLoS One, 6, 2011, e14494.
    • (2011) PLoS One , vol.6 , pp. e14494
    • Podolska, A.1
  • 10
    • 84954068135 scopus 로고    scopus 로고
    • Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation
    • 10 Brites, D., Fernandes, A., Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation. Front. Cell. Neurosci., 9, 2015, 476.
    • (2015) Front. Cell. Neurosci. , vol.9 , pp. 476
    • Brites, D.1    Fernandes, A.2
  • 11
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • 11 Friedman, R.C., et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19 (2009), 92–105.
    • (2009) Genome Res. , vol.19 , pp. 92-105
    • Friedman, R.C.1
  • 12
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • 12 Ebert, M.S., Sharp, P.A., Roles for microRNAs in conferring robustness to biological processes. Cell 149 (2012), 515–524.
    • (2012) Cell , vol.149 , pp. 515-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 13
    • 84923225744 scopus 로고    scopus 로고
    • The biological functions of miRNAs: lessons from in vivo studies
    • 13 Vidigal, J.A., Ventura, A., The biological functions of miRNAs: lessons from in vivo studies. Trends Cell Biol. 25 (2014), 137–147.
    • (2014) Trends Cell Biol. , vol.25 , pp. 137-147
    • Vidigal, J.A.1    Ventura, A.2
  • 14
    • 2142708114 scopus 로고    scopus 로고
    • A short history of a short RNA
    • 14 Lee, R., et al. A short history of a short RNA. Cell 116 (2004), S89–S92.
    • (2004) Cell , vol.116 , pp. S89-S92
    • Lee, R.1
  • 15
    • 84925448484 scopus 로고    scopus 로고
    • Determining the role of microRNAs in psychiatric disorders
    • 15 Issler, O., Chen, A., Determining the role of microRNAs in psychiatric disorders. Nat. Rev. Neurosci. 16 (2015), 201–212.
    • (2015) Nat. Rev. Neurosci. , vol.16 , pp. 201-212
    • Issler, O.1    Chen, A.2
  • 16
    • 34848821559 scopus 로고    scopus 로고
    • Dicer expression and localization in post-mitotic neurons
    • 16 Barbato, C., et al. Dicer expression and localization in post-mitotic neurons. Brain Res. 1175 (2007), 17–27.
    • (2007) Brain Res. , vol.1175 , pp. 17-27
    • Barbato, C.1
  • 17
    • 34548537573 scopus 로고    scopus 로고
    • A microRNA feedback circuit in midbrain dopamine neurons
    • 17 Kim, J., et al. A microRNA feedback circuit in midbrain dopamine neurons. Science 317 (2007), 1220–1224.
    • (2007) Science , vol.317 , pp. 1220-1224
    • Kim, J.1
  • 18
    • 34447261382 scopus 로고    scopus 로고
    • Cerebellar neurodegeneration in the absence of microRNAs
    • 18 Schaefer, A., et al. Cerebellar neurodegeneration in the absence of microRNAs. J. Exp. Med. 204 (2007), 1553–1558.
    • (2007) J. Exp. Med. , vol.204 , pp. 1553-1558
    • Schaefer, A.1
  • 19
    • 18244385475 scopus 로고    scopus 로고
    • MicroRNAs regulate brain morphogenesis in zebrafish
    • 19 Giraldez, A.J., et al. MicroRNAs regulate brain morphogenesis in zebrafish. Science 308 (2005), 833–838.
    • (2005) Science , vol.308 , pp. 833-838
    • Giraldez, A.J.1
  • 20
    • 63649138643 scopus 로고    scopus 로고
    • miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
    • 20 Cheng, L.C., et al. miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat. Neurosci. 12 (2009), 399–408.
    • (2009) Nat. Neurosci. , vol.12 , pp. 399-408
    • Cheng, L.C.1
  • 21
    • 77950565107 scopus 로고    scopus 로고
    • Cross talk between microRNA and epigenetic regulation in adult neurogenesis
    • 21 Szulwach, K.E., et al. Cross talk between microRNA and epigenetic regulation in adult neurogenesis. J. Cell Biol. 189 (2010), 127–141.
    • (2010) J. Cell Biol. , vol.189 , pp. 127-141
    • Szulwach, K.E.1
  • 22
    • 30344449514 scopus 로고    scopus 로고
    • Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila
    • 22 Ashraf, S.I., et al. Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. Cell 124 (2006), 191–205.
    • (2006) Cell , vol.124 , pp. 191-205
    • Ashraf, S.I.1
  • 23
    • 51649130773 scopus 로고    scopus 로고
    • Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain
    • 23 Lugli, G., et al. Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain. J. Neurochem. 106 (2008), 650–661.
    • (2008) J. Neurochem. , vol.106 , pp. 650-661
    • Lugli, G.1
  • 24
    • 31144479591 scopus 로고    scopus 로고
    • A brain-specific microRNA regulates dendritic spine development
    • 24 Schratt, G.M., et al. A brain-specific microRNA regulates dendritic spine development. Nature 439 (2006), 283–289.
    • (2006) Nature , vol.439 , pp. 283-289
    • Schratt, G.M.1
  • 25
    • 66949168048 scopus 로고    scopus 로고
    • A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
    • 25 Siegel, G., et al. A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat. Cell Biol. 11 (2009), 705–716.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 705-716
    • Siegel, G.1
  • 26
    • 84903593412 scopus 로고    scopus 로고
    • Identification of differentially expressed microRNAs across the developing human brain
    • 26 Ziats, M.N., Rennert, O.M., Identification of differentially expressed microRNAs across the developing human brain. Mol. Psychiatry 19 (2014), 848–852.
    • (2014) Mol. Psychiatry , vol.19 , pp. 848-852
    • Ziats, M.N.1    Rennert, O.M.2
  • 27
    • 84894589405 scopus 로고    scopus 로고
    • Neurodevelopmental and neuropsychiatric disorders represent an interconnected molecular system
    • 27 Cristino, A.S., et al. Neurodevelopmental and neuropsychiatric disorders represent an interconnected molecular system. Mol. Psychiatry 19 (2014), 294–301.
    • (2014) Mol. Psychiatry , vol.19 , pp. 294-301
    • Cristino, A.S.1
  • 28
    • 84896314887 scopus 로고    scopus 로고
    • Novel primate miRNAs coevolved with ancient target genes in germinal zone-specific expression patterns
    • 28 Arcila, M.L., et al. Novel primate miRNAs coevolved with ancient target genes in germinal zone-specific expression patterns. Neuron 81 (2014), 1255–1262.
    • (2014) Neuron , vol.81 , pp. 1255-1262
    • Arcila, M.L.1
  • 29
    • 77249128400 scopus 로고    scopus 로고
    • Evolution of an X-linked primate-specific micro RNA cluster
    • 29 Li, J., et al. Evolution of an X-linked primate-specific micro RNA cluster. Mol. Biol. Evol. 27 (2010), 671–683.
    • (2010) Mol. Biol. Evol. , vol.27 , pp. 671-683
    • Li, J.1
  • 30
    • 84958919986 scopus 로고    scopus 로고
    • Human and primate-specific microRNAs in cancer: evolution, and significance in comparison with more distantly-related research models: the great potential of evolutionary young microRNA in cancer research
    • 30 Koufaris, C., Human and primate-specific microRNAs in cancer: evolution, and significance in comparison with more distantly-related research models: the great potential of evolutionary young microRNA in cancer research. Bioessays 38 (2016), 286–294.
    • (2016) Bioessays , vol.38 , pp. 286-294
    • Koufaris, C.1
  • 31
    • 64949159019 scopus 로고    scopus 로고
    • Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers
    • 31 Zhou, R., Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology 34 (2009), 1395–1405.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1395-1405
    • Zhou, R.1
  • 32
    • 77956677763 scopus 로고    scopus 로고
    • miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants
    • 32 Baudry, A., et al. miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants. Science 329 (2010), 1537–1541.
    • (2010) Science , vol.329 , pp. 1537-1541
    • Baudry, A.1
  • 33
    • 82055164291 scopus 로고    scopus 로고
    • Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16
    • 33 Launay, J.M., et al. Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16. Transl. Psychiatry, 1, 2011, e56.
    • (2011) Transl. Psychiatry , vol.1 , pp. e56
    • Launay, J.M.1
  • 34
    • 84904368019 scopus 로고    scopus 로고
    • MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity
    • 34 Issler, O., et al. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity. Neuron 83 (2014), 344–360.
    • (2014) Neuron , vol.83 , pp. 344-360
    • Issler, O.1
  • 35
    • 84923168061 scopus 로고    scopus 로고
    • β-catenin mediates stress resilience through Dicer1/microRNA regulation
    • 35 Dias, C., et al. β-catenin mediates stress resilience through Dicer1/microRNA regulation. Nature 516 (2014), 51–55.
    • (2014) Nature , vol.516 , pp. 51-55
    • Dias, C.1
  • 36
    • 84931263814 scopus 로고    scopus 로고
    • Dopamine receptor D2 and associated microRNAs are involved in stress susceptibility and resistance to escitalopram treatment
    • 36 Zhang, Y., et al. Dopamine receptor D2 and associated microRNAs are involved in stress susceptibility and resistance to escitalopram treatment. Int. J. Neuropsychopharmacol., 18, 2015, pyv025.
    • (2015) Int. J. Neuropsychopharmacol. , vol.18 , pp. pyv025
    • Zhang, Y.1
  • 37
    • 84979093801 scopus 로고    scopus 로고
    • Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: relevance to depression pathophysiology
    • 37 Dwivedi, Y., et al. Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: relevance to depression pathophysiology. Transl. Psychiatry, 5, 2015, e682.
    • (2015) Transl. Psychiatry , vol.5 , pp. e682
    • Dwivedi, Y.1
  • 38
    • 84929660426 scopus 로고    scopus 로고
    • Differential and converging molecular mechanisms of antidepressants’ action in the hippocampal dentate gyrus
    • 38 Patricio, P., et al. Differential and converging molecular mechanisms of antidepressants’ action in the hippocampal dentate gyrus. Neuropsychopharmacology 40 (2015), 338–349.
    • (2015) Neuropsychopharmacology , vol.40 , pp. 338-349
    • Patricio, P.1
  • 39
    • 84942025337 scopus 로고    scopus 로고
    • miR-182 (microRNA-182) suppression in the hippocampus evokes antidepressant-like effects in rats
    • 39 Li, Y., et al. miR-182 (microRNA-182) suppression in the hippocampus evokes antidepressant-like effects in rats. Prog. Neuropsychopharmacol. Biol. Psychiatry 65 (2016), 96–103.
    • (2016) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.65 , pp. 96-103
    • Li, Y.1
  • 40
    • 84949871278 scopus 로고    scopus 로고
    • MicroRNA-155 deletion reduces anxiety- and depressive-like behaviors in mice
    • 40 Fonken, L.K., et al. MicroRNA-155 deletion reduces anxiety- and depressive-like behaviors in mice. Psychoneuroendocrinology 63 (2016), 362–369.
    • (2016) Psychoneuroendocrinology , vol.63 , pp. 362-369
    • Fonken, L.K.1
  • 41
    • 84877935103 scopus 로고    scopus 로고
    • Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation
    • 41 Rodgers, A.B., et al. Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation. J. Neurosci. 33 (2013), 9003–9012.
    • (2013) J. Neurosci. , vol.33 , pp. 9003-9012
    • Rodgers, A.B.1
  • 42
    • 84946594595 scopus 로고    scopus 로고
    • Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress
    • 42 Rodgers, A.B., et al. Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), 13699–13704.
    • (2015) Proc. Natl. Acad. Sci. U. S. A. , vol.112 , pp. 13699-13704
    • Rodgers, A.B.1
  • 43
    • 84899632427 scopus 로고    scopus 로고
    • Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice
    • 43 Gapp, K., et al. Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice. Nat. Neurosci. 17 (2014), 667–669.
    • (2014) Nat. Neurosci. , vol.17 , pp. 667-669
    • Gapp, K.1
  • 44
    • 77956499084 scopus 로고    scopus 로고
    • Glutamatergic modulators: the future of treating mood disorders?
    • 44 Zarate, C. Jr., et al. Glutamatergic modulators: the future of treating mood disorders?. Harv. Rev. Psychiatry 18 (2010), 293–303.
    • (2010) Harv. Rev. Psychiatry , vol.18 , pp. 293-303
    • Zarate, C.1
  • 45
    • 1442264398 scopus 로고    scopus 로고
    • An open-label trial of riluzole in patients with treatment-resistant major depression
    • 45 Zarate, C.A., et al. An open-label trial of riluzole in patients with treatment-resistant major depression. Am. J. Psychiatry 161 (2004), 171–174.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 171-174
    • Zarate, C.A.1
  • 46
    • 18144375955 scopus 로고    scopus 로고
    • Clinical and cost-effectiveness of electroconvulsive therapy for depressive illness, schizophrenia, catatonia and mania: systematic reviews and economic modelling studies
    • 46 Greenhalgh, J., et al. Clinical and cost-effectiveness of electroconvulsive therapy for depressive illness, schizophrenia, catatonia and mania: systematic reviews and economic modelling studies. Health Technol. Assess. 9 (2005), 1–156.
    • (2005) Health Technol. Assess. , vol.9 , pp. 1-156
    • Greenhalgh, J.1
  • 47
    • 84882939097 scopus 로고    scopus 로고
    • microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus
    • 47 O'Connor, R.M., et al. microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus. Int. J. Neuropsychopharmacol. 16 (2013), 1885–1892.
    • (2013) Int. J. Neuropsychopharmacol. , vol.16 , pp. 1885-1892
    • O'Connor, R.M.1
  • 48
    • 79953166373 scopus 로고    scopus 로고
    • Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
    • 48 Li, N., et al. Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol. Psychiatry 69 (2011), 754–761.
    • (2011) Biol. Psychiatry , vol.69 , pp. 754-761
    • Li, N.1
  • 49
    • 84928881628 scopus 로고    scopus 로고
    • 7-Chlorokynurenic acid (7-CTKA) produces rapid antidepressant-like effects: through regulating hippocampal microRNA expressions involved in TrkB–ERK/Akt signaling pathways in mice exposed to chronic unpredictable mild stress
    • 49 Liu, B.B., et al. 7-Chlorokynurenic acid (7-CTKA) produces rapid antidepressant-like effects: through regulating hippocampal microRNA expressions involved in TrkB–ERK/Akt signaling pathways in mice exposed to chronic unpredictable mild stress. Psychopharmacology 232 (2014), 541–550.
    • (2014) Psychopharmacology , vol.232 , pp. 541-550
    • Liu, B.B.1
  • 50
    • 80053634170 scopus 로고    scopus 로고
    • MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34
    • 50 Haramati, S., et al. MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34. J. Neurosci. 31 (2011), 14191–14203.
    • (2011) J. Neurosci. , vol.31 , pp. 14191-14203
    • Haramati, S.1
  • 51
    • 84977520803 scopus 로고    scopus 로고
    • Hippocampal MicroRNA-124 enhances chronic stress resilience in mice
    • 51 Higuchi, F., Hippocampal MicroRNA-124 enhances chronic stress resilience in mice. J. Neurosci. 36 (2016), 7253–7267.
    • (2016) J. Neurosci. , vol.36 , pp. 7253-7267
    • Higuchi, F.1
  • 52
    • 84908353532 scopus 로고    scopus 로고
    • Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients
    • 52 Fan, H.M., et al. Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients. J. Psychiatr. Res. 59 (2014), 45–52.
    • (2014) J. Psychiatr. Res. , vol.59 , pp. 45-52
    • Fan, H.M.1
  • 53
    • 84878707685 scopus 로고    scopus 로고
    • Circulating microRNAs: a novel class of potential biomarkers for diagnosing and prognosing central nervous system diseases
    • 53 Jin, X.F., et al. Circulating microRNAs: a novel class of potential biomarkers for diagnosing and prognosing central nervous system diseases. Cell. Mol. Neurobiol. 33 (2013), 601–613.
    • (2013) Cell. Mol. Neurobiol. , vol.33 , pp. 601-613
    • Jin, X.F.1
  • 54
    • 84959440273 scopus 로고    scopus 로고
    • Multimarker analysis suggests the involvement of BDNF signaling and microRNA biosynthesis in suicidal behavior
    • 54 Pulay, A.J., Rethelyi, J.M., Multimarker analysis suggests the involvement of BDNF signaling and microRNA biosynthesis in suicidal behavior. Am. J. Med. Genet. B Neuropsychiatr. Genet. 171 (2016), 763–776.
    • (2016) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.171 , pp. 763-776
    • Pulay, A.J.1    Rethelyi, J.M.2
  • 55
    • 84949255504 scopus 로고    scopus 로고
    • DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression
    • 55 Wingo, A.P., DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nat. Commu., 6, 2015, 10106.
    • (2015) Nat. Commu. , vol.6 , pp. 10106
    • Wingo, A.P.1
  • 56
    • 84968879671 scopus 로고    scopus 로고
    • Peripheral whole blood microRNA alterations in major depression and bipolar disorder
    • 56 Maffioletti, E., et al. Peripheral whole blood microRNA alterations in major depression and bipolar disorder. J. Affect. Disord. 200 (2016), 250–258.
    • (2016) J. Affect. Disord. , vol.200 , pp. 250-258
    • Maffioletti, E.1
  • 57
    • 84927716490 scopus 로고    scopus 로고
    • MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression
    • 57 Maheu, M., et al. MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression. Transl. Psychiatry, 5, 2015, e511.
    • (2015) Transl. Psychiatry , vol.5 , pp. e511
    • Maheu, M.1
  • 58
    • 84869756304 scopus 로고    scopus 로고
    • Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode
    • 58 Belzeaux, R., et al. Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode. Transl. Psychiatry, 2, 2012, e185.
    • (2012) Transl. Psychiatry , vol.2 , pp. e185
    • Belzeaux, R.1
  • 59
    • 84928178273 scopus 로고    scopus 로고
    • Coordinated messenger RNA/microRNA changes in fibroblasts of patients with major depression
    • 59 Garbett, K.A., et al. Coordinated messenger RNA/microRNA changes in fibroblasts of patients with major depression. Biol. Psychiatry 77 (2014), 256–265.
    • (2014) Biol. Psychiatry , vol.77 , pp. 256-265
    • Garbett, K.A.1
  • 60
    • 84878393663 scopus 로고    scopus 로고
    • Rapid effects of deep brain stimulation for treatment-resistant major depression
    • 60 Schlaepfer, T.E., et al. Rapid effects of deep brain stimulation for treatment-resistant major depression. Biol. Psychiatry 73 (2013), 1204–1212.
    • (2013) Biol. Psychiatry , vol.73 , pp. 1204-1212
    • Schlaepfer, T.E.1
  • 61
    • 84876435649 scopus 로고    scopus 로고
    • Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation–induced splicing changes that classify brain region transcriptomes
    • 61 Soreq, L., et al. Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation–induced splicing changes that classify brain region transcriptomes. Front. Mol. Neurosci., 6, 2013, 10.
    • (2013) Front. Mol. Neurosci. , vol.6 , pp. 10
    • Soreq, L.1
  • 62
    • 84904045942 scopus 로고    scopus 로고
    • miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment
    • 62 Lopez, J.P., et al. miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. Nat. Med. 20 (2014), 764–768.
    • (2014) Nat. Med. , vol.20 , pp. 764-768
    • Lopez, J.P.1
  • 63
    • 84982728594 scopus 로고    scopus 로고
    • MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c
    • 63 Gururajan, A., MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c. Transl. Psychiatry, 6, 2016, e862.
    • (2016) Transl. Psychiatry , vol.6 , pp. e862
    • Gururajan, A.1
  • 64
    • 80055010224 scopus 로고    scopus 로고
    • MicroRNA expression in rat brain exposed to repeated inescapable shock: differential alterations in learned helplessness vs. non-learned helplessness
    • 64 Smalheiser, N.R., et al. MicroRNA expression in rat brain exposed to repeated inescapable shock: differential alterations in learned helplessness vs. non-learned helplessness. Int. J. Neuropsychopharmacol. 14 (2011), 1315–1525.
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 1315-1525
    • Smalheiser, N.R.1
  • 65
    • 84895522921 scopus 로고    scopus 로고
    • Enoxacin elevates microRNA levels in rat frontal cortex and prevents learned helplessness
    • 65 Smalheiser, N.R., et al. Enoxacin elevates microRNA levels in rat frontal cortex and prevents learned helplessness. Front. Psychiatry, 5, 2014, 6.
    • (2014) Front. Psychiatry , vol.5 , pp. 6
    • Smalheiser, N.R.1
  • 66
    • 79952717616 scopus 로고    scopus 로고
    • Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
    • 66 Melo, S., et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 4394–4399.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 4394-4399
    • Melo, S.1
  • 67
    • 49449096792 scopus 로고    scopus 로고
    • A small molecule enhances RNA interference and promotes microRNA processing
    • 67 Shan, G., et al. A small molecule enhances RNA interference and promotes microRNA processing. Nat. Biotechnol. 26 (2008), 933–940.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 933-940
    • Shan, G.1
  • 68
    • 84857970678 scopus 로고    scopus 로고
    • MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects
    • 68 Smalheiser, N.R., et al. MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects. PLoS One, 7, 2012, e33201.
    • (2012) PLoS One , vol.7 , pp. e33201
    • Smalheiser, N.R.1
  • 69
    • 84920669681 scopus 로고    scopus 로고
    • Convergence of advances in genomics, team science, and repositories as drivers of progress in psychiatric genomics
    • 69 Lehner, T., et al. Convergence of advances in genomics, team science, and repositories as drivers of progress in psychiatric genomics. Biol. Psychiatry 77 (2015), 6–14.
    • (2015) Biol. Psychiatry , vol.77 , pp. 6-14
    • Lehner, T.1
  • 70
    • 78149357726 scopus 로고    scopus 로고
    • A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform
    • 70 Xu, Y., et al. A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform. J. Affect. Disord. 127 (2010), 332–336.
    • (2010) J. Affect. Disord. , vol.127 , pp. 332-336
    • Xu, Y.1
  • 71
    • 84930650455 scopus 로고    scopus 로고
    • Genetic variants in the promoters of let-7 family are associated with an increased risk of major depressive disorder
    • 71 Liang, Y., et al. Genetic variants in the promoters of let-7 family are associated with an increased risk of major depressive disorder. J. Affect. Disord. 183 (2015), 295–299.
    • (2015) J. Affect. Disord. , vol.183 , pp. 295-299
    • Liang, Y.1
  • 72
    • 84893795698 scopus 로고    scopus 로고
    • The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders
    • 72 Jensen, K.P., et al. The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders. Am. J. Med. Genet. B Neuropsychiatr. Genet. 165B (2014), 175–183.
    • (2014) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.165B , pp. 175-183
    • Jensen, K.P.1
  • 73
    • 84884562308 scopus 로고    scopus 로고
    • Therapeutic action of fluoxetine is associated with a reduction in prefrontal cortical miR–1971 expression levels in a mouse model of posttraumatic stress disorder
    • 73 Schmidt, U., et al. Therapeutic action of fluoxetine is associated with a reduction in prefrontal cortical miR–1971 expression levels in a mouse model of posttraumatic stress disorder. Front. Psychiatry, 4, 2013, 66.
    • (2013) Front. Psychiatry , vol.4 , pp. 66
    • Schmidt, U.1
  • 74
    • 84899896406 scopus 로고    scopus 로고
    • A preliminary analysis of association between the down-regulation of microRNA-181b expression and symptomatology improvement in schizophrenia patients before and after antipsychotic treatment
    • 74 Song, H.T., et al. A preliminary analysis of association between the down-regulation of microRNA-181b expression and symptomatology improvement in schizophrenia patients before and after antipsychotic treatment. J. Psychiatr. Res. 54 (2014), 134–140.
    • (2014) J. Psychiatr. Res. , vol.54 , pp. 134-140
    • Song, H.T.1
  • 75
    • 41849133938 scopus 로고    scopus 로고
    • Dysregulation of miRNA 181b in the temporal cortex in schizophrenia
    • 75 Beveridge, N.J., et al. Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum. Mol. Genet. 17 (2008), 1156–1168.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 1156-1168
    • Beveridge, N.J.1
  • 76
    • 34249736846 scopus 로고    scopus 로고
    • microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder
    • 76 Perkins, D.O., et al. microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol., 8, 2007, R27.
    • (2007) Genome Biol. , vol.8 , pp. R27
    • Perkins, D.O.1
  • 77
    • 84886296689 scopus 로고    scopus 로고
    • Replication in a Japanese population that a MIR30E gene variation is associated with schizophrenia
    • 77 Watanabe, Y., et al. Replication in a Japanese population that a MIR30E gene variation is associated with schizophrenia. Schizophr. Res. 150 (2013), 596–597.
    • (2013) Schizophr. Res. , vol.150 , pp. 596-597
    • Watanabe, Y.1
  • 78
    • 77952670366 scopus 로고    scopus 로고
    • MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia
    • 78 Xu, Y., et al. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. Schizophr. Res. 119 (2010), 219–227.
    • (2010) Schizophr. Res. , vol.119 , pp. 219-227
    • Xu, Y.1
  • 79
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • 79 Schizophrenia Psychiatric Genome-Wide Association Study Consortium. Genome-wide association study identifies five new schizophrenia loci. Nat. Genet. 43 (2011), 969–976.
    • (2011) Nat. Genet. , vol.43 , pp. 969-976
  • 80
    • 84880134983 scopus 로고    scopus 로고
    • Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex
    • 80 Guella, I., et al. Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex. J. Psychiatr. Res. 47 (2013), 1215–1221.
    • (2013) J. Psychiatr. Res. , vol.47 , pp. 1215-1221
    • Guella, I.1
  • 81
    • 84926139786 scopus 로고    scopus 로고
    • MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene sets
    • 81 Strazisar, M., et al. MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene sets. Mol. Psychiatry, 2014, 472–481.
    • (2014) Mol. Psychiatry , pp. 472-481
    • Strazisar, M.1
  • 82
    • 84871058700 scopus 로고    scopus 로고
    • Mood congruent psychotic symptoms and specific cognitive deficits in carriers of the novel schizophrenia risk variant at MIR-137
    • 82 Cummings, E., et al. Mood congruent psychotic symptoms and specific cognitive deficits in carriers of the novel schizophrenia risk variant at MIR-137. Neurosci. Lett. 532 (2013), 33–38.
    • (2013) Neurosci. Lett. , vol.532 , pp. 33-38
    • Cummings, E.1
  • 83
    • 84879410405 scopus 로고    scopus 로고
    • Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia
    • 83 Green, M.J., et al. Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia. Mol. Psychiatry 18 (2013), 774–780.
    • (2013) Mol. Psychiatry , vol.18 , pp. 774-780
    • Green, M.J.1
  • 84
    • 84875466500 scopus 로고    scopus 로고
    • The genome-wide supported microRNA-137 variant predicts phenotypic heterogeneity within schizophrenia
    • 84 Lett, T.A., et al. The genome-wide supported microRNA-137 variant predicts phenotypic heterogeneity within schizophrenia. Mol. Psychiatry 18 (2013), 443–450.
    • (2013) Mol. Psychiatry , vol.18 , pp. 443-450
    • Lett, T.A.1
  • 85
    • 84904504311 scopus 로고    scopus 로고
    • The impact of MIR137 on dorsolateral prefrontal-hippocampal functional connectivity in healthy subjects
    • 85 Liu, B., et al. The impact of MIR137 on dorsolateral prefrontal-hippocampal functional connectivity in healthy subjects. Neuropsychopharmacology, 2014, 2153–2160.
    • (2014) Neuropsychopharmacology , pp. 2153-2160
    • Liu, B.1
  • 86
    • 84867576049 scopus 로고    scopus 로고
    • Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder
    • 86 Whalley, H.C., et al. Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder. Neuropsychopharmacology 37 (2012), 2720–2729.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2720-2729
    • Whalley, H.C.1
  • 87
    • 84871270974 scopus 로고    scopus 로고
    • Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets
    • 87 Kwon, E., et al. Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets. Mol. Psychiatry 18 (2013), 11–12.
    • (2013) Mol. Psychiatry , vol.18 , pp. 11-12
    • Kwon, E.1
  • 88
    • 84865985475 scopus 로고    scopus 로고
    • Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137
    • 88 Kim, A.H., et al. Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137. Schizophr. Res. 141 (2012), 60–64.
    • (2012) Schizophr. Res. , vol.141 , pp. 60-64
    • Kim, A.H.1
  • 89
    • 84959496426 scopus 로고    scopus 로고
    • The schizophrenia risk gene MIR137 acts as a hippocampal gene network node orchestrating the expression of genes relevant to nervous system development and function
    • Published online February 27, 2016
    • 89 Olde Loohuis, N.F., et al. The schizophrenia risk gene MIR137 acts as a hippocampal gene network node orchestrating the expression of genes relevant to nervous system development and function. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2016, 10.1016/j.pnpbp.2016.02.009 Published online February 27, 2016.
    • (2016) Prog. Neuropsychopharmacol. Biol. Psychiatry
    • Olde Loohuis, N.F.1
  • 90
    • 84899835835 scopus 로고    scopus 로고
    • Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells
    • 90 Tamim, S., et al. Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells. PLoS One, 9, 2014, e85591.
    • (2014) PLoS One , vol.9 , pp. e85591
    • Tamim, S.1
  • 91
    • 84906808322 scopus 로고    scopus 로고
    • MicroRNA-137 regulates a glucocorticoid receptor-dependent signalling network: implications for the etiology of schizophrenia
    • 91 Valles, A., et al. MicroRNA-137 regulates a glucocorticoid receptor-dependent signalling network: implications for the etiology of schizophrenia. J. Psychiatry Neurosci., 39, 2014, 130269.
    • (2014) J. Psychiatry Neurosci. , vol.39 , pp. 130269
    • Valles, A.1
  • 92
    • 84857419568 scopus 로고    scopus 로고
    • MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function
    • 92 Miller, B.H., et al. MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 3125–3130.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 3125-3130
    • Miller, B.H.1
  • 93
    • 48249095979 scopus 로고    scopus 로고
    • An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP
    • 93 Wayman, G.A., et al. An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 9093–9098.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 9093-9098
    • Wayman, G.A.1
  • 94
    • 84897529575 scopus 로고    scopus 로고
    • MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway
    • 128–113
    • 94 Xiao, J., et al. MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway. Neuroscience, 268, 2014 128–113.
    • (2014) Neuroscience , vol.268
    • Xiao, J.1
  • 95
    • 58049147045 scopus 로고    scopus 로고
    • Neurobiological substrates for the dark side of compulsivity in addiction
    • 95 Koob, G.F., Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology 56:Suppl. 1 (2009), 18–31.
    • (2009) Neuropharmacology , vol.56 , pp. 18-31
    • Koob, G.F.1
  • 96
    • 84959552558 scopus 로고    scopus 로고
    • Corticostriatal microRNAs in addiction
    • 96 Heyer, M.P., Kenny, P.J., Corticostriatal microRNAs in addiction. Brain Res. 1628 (2015), 2–16.
    • (2015) Brain Res. , vol.1628 , pp. 2-16
    • Heyer, M.P.1    Kenny, P.J.2
  • 97
    • 84869079253 scopus 로고    scopus 로고
    • Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs
    • 97 Jonkman, S., Kenny, P.J., Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs. Neuropsychopharmacology 38 (2013), 198–211.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 198-211
    • Jonkman, S.1    Kenny, P.J.2
  • 98
    • 33748371601 scopus 로고    scopus 로고
    • Neural mechanisms of addiction: the role of reward-related learning and memory
    • 98 Hyman, S.E., et al. Neural mechanisms of addiction: the role of reward-related learning and memory. Ann. Rev. Neurosci. 29 (2006), 565–598.
    • (2006) Ann. Rev. Neurosci. , vol.29 , pp. 565-598
    • Hyman, S.E.1
  • 100
    • 34249819336 scopus 로고    scopus 로고
    • MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
    • 100 Tsang, J., et al. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol. Cell 26 (2007), 753–767.
    • (2007) Mol. Cell , vol.26 , pp. 753-767
    • Tsang, J.1
  • 101
    • 18744361871 scopus 로고    scopus 로고
    • Enhancement of cellular memory by reducing stochastic transitions
    • 101 Acar, M., et al. Enhancement of cellular memory by reducing stochastic transitions. Nature 435 (2005), 228–232.
    • (2005) Nature , vol.435 , pp. 228-232
    • Acar, M.1
  • 102
    • 38049062478 scopus 로고    scopus 로고
    • Posttranscriptional control of neuronal development by microRNA networks
    • 102 Gao, F.B., Posttranscriptional control of neuronal development by microRNA networks. Trends Neurosci. 31 (2008), 20–26.
    • (2008) Trends Neurosci. , vol.31 , pp. 20-26
    • Gao, F.B.1
  • 103
    • 41349096445 scopus 로고    scopus 로고
    • Gene regulation by transcription factors and microRNAs
    • 103 Hobert, O., Gene regulation by transcription factors and microRNAs. Science 319 (2008), 1785–1786.
    • (2008) Science , vol.319 , pp. 1785-1786
    • Hobert, O.1
  • 104
    • 77956252381 scopus 로고    scopus 로고
    • Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction
    • 104 Schaefer, A., et al. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. J. Exp. Med. 207 (2010), 1843–1851.
    • (2010) J. Exp. Med. , vol.207 , pp. 1843-1851
    • Schaefer, A.1
  • 105
    • 70449530430 scopus 로고    scopus 로고
    • microRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticity
    • 105 Chandrasekar, V., Dreyer, J.L., microRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticity. Mol. Cell. Neurosci. 42 (2009), 350–362.
    • (2009) Mol. Cell. Neurosci. , vol.42 , pp. 350-362
    • Chandrasekar, V.1    Dreyer, J.L.2
  • 106
    • 79954588293 scopus 로고    scopus 로고
    • Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference
    • 106 Chandrasekar, V., Dreyer, J.L., Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference. Neuropsychopharmacology 36 (2011), 1149–1164.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1149-1164
    • Chandrasekar, V.1    Dreyer, J.L.2
  • 107
    • 79960463343 scopus 로고    scopus 로고
    • microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs
    • 107 Eipper-Mains, J.E., et al. microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs. RNA 17 (2011), 1529–1543.
    • (2011) RNA , vol.17 , pp. 1529-1543
    • Eipper-Mains, J.E.1
  • 108
    • 77954510708 scopus 로고    scopus 로고
    • Striatal microRNA controls cocaine intake through CREB signalling
    • 108 Hollander, J.A., et al. Striatal microRNA controls cocaine intake through CREB signalling. Nature 466 (2010), 197–202.
    • (2010) Nature , vol.466 , pp. 197-202
    • Hollander, J.A.1
  • 109
    • 77956141295 scopus 로고    scopus 로고
    • MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212
    • 109 Im, H.I., et al. MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. Nat. Neurosci. 13 (2010), 1120–1127.
    • (2010) Nat. Neurosci. , vol.13 , pp. 1120-1127
    • Im, H.I.1
  • 110
    • 84883520165 scopus 로고    scopus 로고
    • MicroRNAs and drug addiction
    • 110 Bali, P., Kenny, P.J., MicroRNAs and drug addiction. Front Genet., 4, 2013, 43.
    • (2013) Front Genet. , vol.4 , pp. 43
    • Bali, P.1    Kenny, P.J.2
  • 111
    • 84927712962 scopus 로고    scopus 로고
    • Distinct miRNA expression in dorsal striatal subregions is associated with risk for addiction in rats
    • 111 Quinn, R.K., et al. Distinct miRNA expression in dorsal striatal subregions is associated with risk for addiction in rats. Transl. Psychiatry, 5, 2015, e503.
    • (2015) Transl. Psychiatry , vol.5 , pp. e503
    • Quinn, R.K.1
  • 112
    • 47749120244 scopus 로고    scopus 로고
    • Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol
    • 112 Pietrzykowski, A.Z., et al. Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol. Neuron 59 (2008), 274–287.
    • (2008) Neuron , vol.59 , pp. 274-287
    • Pietrzykowski, A.Z.1
  • 113
    • 84892707133 scopus 로고    scopus 로고
    • Integration of miRNA and protein profiling reveals coordinated neuroadaptations in the alcohol-dependent mouse brain
    • 113 Gorini, G., et al. Integration of miRNA and protein profiling reveals coordinated neuroadaptations in the alcohol-dependent mouse brain. PLoS One, 8, 2013, e82565.
    • (2013) PLoS One , vol.8 , pp. e82565
    • Gorini, G.1
  • 114
    • 84880329046 scopus 로고    scopus 로고
    • Striatal modulation of BDNF expression using microRNA124a-expressing lentiviral vectors impairs ethanol-induced conditioned-place preference and voluntary alcohol consumption
    • 114 Bahi, A., Dreyer, J.L., Striatal modulation of BDNF expression using microRNA124a-expressing lentiviral vectors impairs ethanol-induced conditioned-place preference and voluntary alcohol consumption. Eur. J. Neurosci. 38 (2013), 2328–2337.
    • (2013) Eur. J. Neurosci. , vol.38 , pp. 2328-2337
    • Bahi, A.1    Dreyer, J.L.2
  • 115
    • 84902385488 scopus 로고    scopus 로고
    • A genetic variant in the microRNA-146a gene is associated with susceptibility to alcohol use disorders
    • 115 Novo-Veleiro, I., et al. A genetic variant in the microRNA-146a gene is associated with susceptibility to alcohol use disorders. Eur. Psychiatry 29 (2014), 288–292.
    • (2014) Eur. Psychiatry , vol.29 , pp. 288-292
    • Novo-Veleiro, I.1
  • 116
    • 84859005549 scopus 로고    scopus 로고
    • Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression
    • 116 O'Connor, R.M., et al. Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression. Mol. Psychiatry 17 (2012), 359–376.
    • (2012) Mol. Psychiatry , vol.17 , pp. 359-376
    • O'Connor, R.M.1
  • 117
    • 83755205460 scopus 로고    scopus 로고
    • Interactions between antidepressants and P-glycoprotein at the blood–brain barrier: clinical significance of in vitro and in vivo findings
    • 117 O'Brien, F.E., et al. Interactions between antidepressants and P-glycoprotein at the blood–brain barrier: clinical significance of in vitro and in vivo findings. Br. J. Pharmacol. 165 (2012), 289–312.
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 289-312
    • O'Brien, F.E.1
  • 118
    • 84884222342 scopus 로고    scopus 로고
    • P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents
    • 118 O'Brien, F.E., et al. P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents. Neuropsychopharmacology 38 (2013), 2209–2219.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 2209-2219
    • O'Brien, F.E.1
  • 119
    • 84862286848 scopus 로고    scopus 로고
    • Intranasal treatment of neurodegenerative diseases and stroke
    • 119 Gomez, D., et al. Intranasal treatment of neurodegenerative diseases and stroke. Front. Biosci. 4 (2012), 74–89.
    • (2012) Front. Biosci. , vol.4 , pp. 74-89
    • Gomez, D.1
  • 120
    • 84969287518 scopus 로고    scopus 로고
    • Intrathecal injections in children with spinal muscular atrophy: Nusinersen Clinical Trial Experience
    • 120 Hache, M., et al. Intrathecal injections in children with spinal muscular atrophy: Nusinersen Clinical Trial Experience. J. Child. Neurol. 31 (2016), 899–906.
    • (2016) J. Child. Neurol. , vol.31 , pp. 899-906
    • Hache, M.1
  • 121
    • 77950843538 scopus 로고    scopus 로고
    • The dicey role of Dicer: implications for RNAi therapy
    • 121 Merritt, W.M., et al. The dicey role of Dicer: implications for RNAi therapy. Cancer Res. 70 (2010), 2571–2574.
    • (2010) Cancer Res. , vol.70 , pp. 2571-2574
    • Merritt, W.M.1
  • 122
    • 74249112787 scopus 로고    scopus 로고
    • Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
    • 122 Lanford, R.E., et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327 (2010), 198–201.
    • (2010) Science , vol.327 , pp. 198-201
    • Lanford, R.E.1
  • 123
    • 84907484544 scopus 로고    scopus 로고
    • Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients
    • 123 van der Ree, M.H., et al. Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients. Antiviral Res. 111 (2014), 53–59.
    • (2014) Antiviral Res. , vol.111 , pp. 53-59
    • van der Ree, M.H.1
  • 124
    • 44849140430 scopus 로고    scopus 로고
    • Gene therapy of inherited diseases
    • 124 Fischer, A., Cavazzana-Calvo, M., Gene therapy of inherited diseases. Lancet 371 (2008), 2044–2047.
    • (2008) Lancet , vol.371 , pp. 2044-2047
    • Fischer, A.1    Cavazzana-Calvo, M.2
  • 125
    • 84861577379 scopus 로고    scopus 로고
    • An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
    • 125 Lehmann, S.M., et al. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat. Neurosci. 15 (2012), 827–835.
    • (2012) Nat. Neurosci. , vol.15 , pp. 827-835
    • Lehmann, S.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.