Intrathecal Injections in Children with Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience

Journal of Child Neurology

Volumn 31, Issue 7, 2016, Pages 899-906

  Haché, Manon ^a   Swoboda, Kathryn J ^b   Sethna, Navil ^c   Farrow Gillespie, Alan ^d   Khandji, Alexander ^e   Xia, Shuting ^f   Bishop, Kathie M ^f  

^a NewYork Presbyterian Hospital   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f ISIS PHARMACEUTICALS   (United States)

Author keywords

antisense oligonucleotide; drug delivery; lumbar puncture; spinal muscular atrophy

Indexed keywords

CAFFEINE CITRATE; IBUPROFEN; NUSINERSEN; PARACETAMOL; MUSCLE RELAXANT AGENT; OLIGONUCLEOTIDE;

ADOLESCENT; ANTISENSE THERAPY; ARTICLE; BACKACHE; BED REST; BLOOD PATCH; CEREBROSPINAL FLUID; CHILD; CLINICAL ARTICLE; CONSERVATIVE TREATMENT; DEHYDRATION; DRUG DOSE ESCALATION; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FLUOROSCOPY; HUMAN; HYPOTENSION; INJECTION SITE PAIN; LIMB PAIN; LUMBAR PUNCTURE; MALE; NAUSEA; OPEN STUDY; PARESTHESIA; PHASE 1 CLINICAL TRIAL; POSTDURAL PUNCTURE HEADACHE; PRESCHOOL CHILD; PRIORITY JOURNAL; RADIATION EXPOSURE; SCOLIOSIS; SPINAL MUSCULAR ATROPHY; VOMITING; CLINICAL TRIAL; INTRASPINAL DRUG ADMINISTRATION;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INJECTIONS, SPINAL; MALE; MUSCULAR ATROPHY, SPINAL; NEUROMUSCULAR AGENTS; OLIGONUCLEOTIDES; SPINAL PUNCTURE;

EID: 84969287518     PISSN: 08830738     EISSN: 17088283     Source Type: Journal    
DOI: 10.1177/0883073815627882     Document Type: Article

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