Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s Interaction

Cell

Volumn 167, Issue 4, 2016, Pages 1052-1066.e18

  Liu, Junli ^a   Ibi, Dorina ^a   Taniguchi, Koji ^b,c   Lee, Jaemin ^a   Herrema, Hilde ^a   Akosman, Bedia ^a   Mucka, Patrick ^a   Salazar Hernandez, Mario Andres ^a   Uyar, Muhemmet Fatih ^a   Park, Sang Won ^a   Karin, Michael ^b,c   Ozcan, Umut ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b San Diego   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

diabetes; ER stress; glucose metabolism; IKK ; inflammation; insulin resistance; obesity; unfolded protein response; UPR; XBP1s

Indexed keywords

I KAPPA B KINASE BETA; X BOX BINDING PROTEIN 1; GLUCOSE; I KAPPA B KINASE; IKBKB PROTEIN, MOUSE; XBP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; INFLAMMATION; INSULIN SENSITIVITY; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; UPREGULATION; ANIMAL; C57BL MOUSE; HOMEOSTASIS; HUMAN; LIVER; MALE; METABOLISM; MOUSE MUTANT; NON INSULIN DEPENDENT DIABETES MELLITUS; PHOSPHORYLATION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; GLUCOSE; HOMEOSTASIS; HUMANS; I-KAPPA B KINASE; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; PHOSPHORYLATION; PROTEIN STABILITY; X-BOX BINDING PROTEIN 1;

EID: 84995595712     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.10.015     Document Type: Article

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