Involvement of transcription factor XBP1s in the resistance of HDAC6 inhibitor Tubastatin A to superoxidation via acetylation-mediated proteasomal degradation

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 433-439

  Zhang, Yue ^a,b   Liu, Chang Mei ^a,b   Cao, Xian Cao ^a,b   Zang, Yi ^b   Zhou, Yu Bo ^b   Li, Jia ^a,b  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

HDAC6; Oxidative stress; Transcription regulation; Tubastatin A; XBP1s

Indexed keywords

HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 6 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; PROTEASOME; TUBASTATIN A; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ACETYLATION; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL GROWTH; CELL PROTECTION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RAT; TRANSCRIPTION REGULATION; UPREGULATION;

HDAC6; OXIDATIVE STRESS; TRANSCRIPTION REGULATION; TUBASTATIN A; XBP1S;

ACETYLATION; ANIMALS; DNA-BINDING PROTEINS; DRUG RESISTANCE; HEK293 CELLS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; INDOLES; PC12 CELLS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84904768641     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.05.134     Document Type: Article

References (33)

1. Y. Zhang, S. Kwon, T. Yamaguchi, F. Cubizolles, S. Rousseaux, M. Kneissel, C. Cao, N. Li, H.L. Cheng, K. Chua, D. Lombard, A. Mizeracki, G. Matthias, F.W. Alt, S. Khochbin, and P. Matthias Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally Mol. Cell. Biol. 28 2008 1688 1701
2. C. Hubbert, A. Guardiola, R. Shao, Y. Kawaguchi, A. Ito, A. Nixon, M. Yoshida, X.F. Wang, and T.P. Yao HDAC6 is a microtubule-associated deacetylase Nature 417 2002 455 458
3. X. Zhang, Z. Yuan, Y. Zhang, S. Yong, A. Salas-Burgos, J. Koomen, N. Olashaw, J.T. Parsons, X.J. Yang, S.R. Dent, T.P. Yao, W.S. Lane, and E. Seto HDAC6 modulates cell motility by altering the acetylation level of cortactin Mol. Cell 27 2007 197 213
4. J.J. Kovacs, P.J. Murphy, S. Gaillard, X. Zhao, J.T. Wu, C.V. Nicchitta, M. Yoshida, D.O. Toft, W.B. Pratt, and T.P. Yao HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor Mol. Cell 18 2005 601 607
5. X. Tang, J.S. Gao, Y.J. Guan, K.E. McLane, Z.L. Yuan, B. Ramratnam, and Y.E. Chin Acetylation-dependent signal transduction for type I interferon receptor Cell 131 2007 93 105
6. R.B. Parmigiani, W.S. Xu, G. Venta-Perez, H. Erdjument-Bromage, M. Yaneva, P. Tempst, and P.A. Marks HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation Proc. Natl. Acad. Sci. USA 105 2008 9633 9638
7. C. d'Ydewalle, E. Bogaert, and L. Van Den Bosch HDAC6 at the intersection of neuroprotection and neurodegeneration Traffic 13 2012 771 779
8. G. Li, H. Jiang, M. Chang, H. Xie, and L. Hu HDAC6 alpha-tubulin deacetylase: a potential therapeutic target in neurodegenerative diseases J. Neurol. Sci. 304 2011 1 8
9. K.J. Barnham, C.L. Masters, and A.I. Bush Neurodegenerative diseases and oxidative stress Nat. Rev. Drug Discovery 3 2004 205 214
10. K.V. Butler, J. Kalin, C. Brochier, G. Vistoli, B. Langley, and A.P. Kozikowski Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, Tubastatin A J. Am. Chem. Soc. 132 2010 10842 10846
11. Y.M. Ma, Y.B. Zhou, C.M. Xie, D.M. Chen, and J. Li Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells Acta Pharmacol. Sin. 33 2012 407 417
12. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402 408
13. T. Kamitani, K. Kito, H.P. Nguyen, and E.T. Yeh Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein J. Biol. Chem. 272 1997 28557 28562
14. H. Sha, Y. He, H. Chen, C. Wang, A. Zenno, H. Shi, X. Yang, X. Zhang, and L. Qi The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis Cell Metab. 9 2009 556 564
15. D.P. Gelain, R.J. Dalmolin, V.L. Belau, J.C. Moreira, F. Klamt, and M.A. Castro A systematic review of human antioxidant genes Front. Biosci. 14 2009 4457 4463
16. D. Acosta-Alvear, Y. Zhou, A. Blais, M. Tsikitis, N.H. Lents, C. Arias, C.J. Lennon, Y. Kluger, and B.D. Dynlacht XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks Mol. Cell 27 2007 53 66
17. B. Tirosh, N.N. Iwakoshi, L.H. Glimcher, and H.L. Ploegh Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response J. Biol. Chem. 281 2006 5852 5860
18. S. Cenci, A. Mezghrani, P. Cascio, G. Bianchi, F. Cerruti, A. Fra, H. Lelouard, S. Masciarelli, L. Mattioli, L. Oliva, A. Orsi, E. Pasqualetto, P. Pierre, E. Ruffato, L. Tagliavacca, and R. Sitia Progressively impaired proteasomal capacity during terminal plasma cell differentiation EMBO J. 25 2006 1104 1113
19. C. Caron, C. Boyault, and S. Khochbin Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability BioEssays 27 2005 408 415
20. P.A. Wade, D. Pruss, and A.P. Wolffe Histone acetylation: chromatin in action Trends Biochem. Sci. 22 1997 128 132
21. J. Luo, F. Su, D. Chen, A. Shiloh, and W. Gu Deacetylation of p53 modulates its effect on cell growth and apoptosis Nature 408 2000 377 381
22. C. Choudhary, C. Kumar, F. Gnad, M.L. Nielsen, M. Rehman, T.C. Walther, J.V. Olsen, and M. Mann Lysine acetylation targets protein complexes and co-regulates major cellular functions Science 325 2009 834 840
23. Y.L. Deribe, P. Wild, A. Chandrashaker, J. Curak, M.H. Schmidt, Y. Kalaidzidis, N. Milutinovic, I. Kratchmarova, L. Buerkle, M.J. Fetchko, P. Schmidt, S. Kittanakom, K.R. Brown, I. Jurisica, B. Blagoev, M. Zerial, I. Stagljar, and I. Dikic Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6 Sci. Signal. 2 2009 ra84
24. P. Penela, V. Lafarga, O. Tapia, V. Rivas, L. Nogues, E. Lucas, R. Vila-Bedmar, C. Murga, and F. Mayor Jr. Roles of GRK2 in cell signaling beyond GPCR desensitization: GRK2-HDAC6 interaction modulates cell spreading and motility Sci. Signal. 5 2012 pt3
25. M.T. Riolo, Z.A. Cooper, M.P. Holloway, Y. Cheng, C. Bianchi, E. Yakirevich, L. Ma, Y.E. Chin, and R.A. Altura Histone deacetylase 6 (HDAC6) deacetylates survivin for its nuclear export in breast cancer J. Biol. Chem. 287 2012 10885 10893
26. S. Kahali, B. Sarcar, A. Prabhu, E. Seto, and P. Chinnaiyan Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response FASEB J. 26 2012 2437 2445
27. Y. Liu, X. Zhang, Y. Liang, H. Yu, X. Chen, T. Zheng, B. Zheng, L. Wang, L. Zhao, C. Shi, and S. Zhao Targeting X box-binding protein-1 (XBP1) enhances sensitivity of glioma cells to oxidative stress Neuropathol. Appl. Neurobiol. 37 2011 395 405
28. Y. Zhong, J. Li, J.J. Wang, C. Chen, J.T. Tran, A. Saadi, Q. Yu, Y.Z. Le, M.N. Mandal, R.E. Anderson, and S.X. Zhang X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium PLoS ONE 7 2012 e38616
29. M. Dokmanovic, C. Clarke, and P.A. Marks Histone deacetylase inhibitors: overview and perspectives Mol. Cancer Res. 5 2007 981 989
30. F.M. Wang, Y.J. Chen, and H.J. Ouyang Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation Biochem. J. 433 2011 245 252
31. N. Gurvich, O.M. Tsygankova, J.L. Meinkoth, and P.S. Klein Histone deacetylase is a target of valproic acid-mediated cellular differentiation Cancer Res. 64 2004 1079 1086
32. Y. Tang, W. Zhao, Y. Chen, Y. Zhao, and W. Gu Acetylation is indispensable for p53 activation Cell 133 2008 612 626
33. H. Geng, Q. Liu, C. Xue, L.L. David, T.M. Beer, G.V. Thomas, M.S. Dai, and D.Z. Qian HIF1alpha protein stability is increased by acetylation at lysine 709 J. Biol. Chem. 287 2012 35496 35505