Alternative lengthening of human telomeres is a conservative DNA replication process with features of break-induced replication

EMBO Reports

Volumn 17, Issue 12, 2016, Pages 1731-1737

  Roumelioti, Fani Marlen ^a   Sotiriou, Sotirios K ^b   Katsini, Vasiliki ^a   Chiourea, Maria ^a   Halazonetis, Thanos D ^b   Gagos, Sarantis ^a  

^a BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

alternative lengthening of telomeres; break induced replication; PolD3; PolD4; telomere length regulation

Indexed keywords

DNA DIRECTED DNA POLYMERASE DELTA; DNA POLYMERASE DELTA 3; DNA POLYMERASE DELTA 4; PEPTIDE NUCLEIC ACID; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE GAMMA; DNA POLYMERASE DELTA P12 SUBUNIT, HUMAN; POL32 PROTEIN, S CEREVISIAE; POLD3 PROTEIN, HUMAN; SACCHAROMYCES CEREVISIAE PROTEIN; TELOMERASE;

ALTERNATIVE LENGTHENING OF TELOMERE; ARTICLE; BREAK INDUCED REPLICATION; CHROMOSOME; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TELOMERE HOMEOSTASIS; TELOMERE LENGTH; U2OS CELL LINE; DEFICIENCY; DNA REPAIR; GENETICS; HOMOLOGOUS RECOMBINATION; METABOLISM; NEOPLASM; PHYSIOLOGY; TELOMERE SHORTENING; YEAST;

DNA BREAKS, DOUBLE-STRANDED; DNA POLYMERASE III; DNA REPAIR; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HOMOLOGOUS RECOMBINATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; NEOPLASMS; SACCHAROMYCES CEREVISIAE PROTEINS; TELOMERASE; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING; YEASTS;

EID: 84995475204     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201643169     Document Type: Article

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