-
1
-
-
78149435151
-
Telomeric strategies: means to an end
-
Jain D., Cooper J.P. Telomeric strategies: means to an end. Annu. Rev. Genet. 2010, 44:243-269.
-
(2010)
Annu. Rev. Genet.
, vol.44
, pp. 243-269
-
-
Jain, D.1
Cooper, J.P.2
-
2
-
-
71149093724
-
How telomeres solve the end-protection problem
-
de Lange T. How telomeres solve the end-protection problem. Science 2009, 326:948-952.
-
(2009)
Science
, vol.326
, pp. 948-952
-
-
de Lange, T.1
-
3
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
Benetti R., et al. Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat. Genet. 2007, 39:243-250.
-
(2007)
Nat. Genet.
, vol.39
, pp. 243-250
-
-
Benetti, R.1
-
4
-
-
0025201982
-
Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription
-
Gottschling D.E., et al. Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 1990, 63:751-762.
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
-
5
-
-
0035874977
-
Telomere position effect in human cells
-
Baur J.A., et al. Telomere position effect in human cells. Science 2001, 292:2075-2077.
-
(2001)
Science
, vol.292
, pp. 2075-2077
-
-
Baur, J.A.1
-
6
-
-
37349043972
-
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
-
Azzalin C.M., et al. Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 2007, 318:798-801.
-
(2007)
Science
, vol.318
, pp. 798-801
-
-
Azzalin, C.M.1
-
7
-
-
38849111756
-
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
-
Schoeftner S., Blasco M.A. Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II. Nat. Cell Biol. 2008, 10:228-236.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 228-236
-
-
Schoeftner, S.1
Blasco, M.A.2
-
8
-
-
84860210469
-
Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast
-
Greenwood J., Cooper J.P. Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast. Nucleic Acids Res. 2012, 40:2956-2963.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 2956-2963
-
-
Greenwood, J.1
Cooper, J.P.2
-
9
-
-
84860176464
-
The telomeric transcriptome of Schizosaccharomyces pombe
-
Bah A., et al. The telomeric transcriptome of Schizosaccharomyces pombe. Nucleic Acids Res. 2012, 40:2995-3005.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 2995-3005
-
-
Bah, A.1
-
10
-
-
55949106494
-
The Rat1p 5' to 3' exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae
-
Luke B., et al. The Rat1p 5' to 3' exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae. Mol. Cell 2008, 32:465-477.
-
(2008)
Mol. Cell
, vol.32
, pp. 465-477
-
-
Luke, B.1
-
11
-
-
73249117060
-
CpG-island promoters drive transcription of human telomeres
-
Nergadze S.G., et al. CpG-island promoters drive transcription of human telomeres. RNA 2009, 15:2186-2194.
-
(2009)
RNA
, vol.15
, pp. 2186-2194
-
-
Nergadze, S.G.1
-
12
-
-
78049386911
-
Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways
-
Porro A., et al. Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways. Mol. Cell. Biol. 2010, 30:4808-4817.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4808-4817
-
-
Porro, A.1
-
13
-
-
84864041566
-
TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends
-
Pfeiffer V., Lingner J. TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends. PLoS Genet. 2012, 8:e1002747.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002747
-
-
Pfeiffer, V.1
Lingner, J.2
-
14
-
-
84866115963
-
Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1alpha
-
Arnoult N., et al. Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1alpha. Nat. Struct. Mol. Biol. 2012, 19:948-956.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 948-956
-
-
Arnoult, N.1
-
15
-
-
84860491777
-
Telomerase efficiently elongates highly transcribing telomeres in human cancer cells
-
Farnung B.O., et al. Telomerase efficiently elongates highly transcribing telomeres in human cancer cells. PLoS ONE 2012, 7:e35714.
-
(2012)
PLoS ONE
, vol.7
, pp. e35714
-
-
Farnung, B.O.1
-
16
-
-
84896708650
-
Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes
-
Lee M., et al. Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes. Nucleic Acids Res. 2014, 42:1733-1746.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 1733-1746
-
-
Lee, M.1
-
17
-
-
84868534644
-
A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection
-
Deng Z., et al. A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. EMBO J. 2012, 31:4165-4178.
-
(2012)
EMBO J.
, vol.31
, pp. 4165-4178
-
-
Deng, Z.1
-
18
-
-
79957983472
-
Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast
-
Iglesias N., et al. Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast. EMBO Rep. 2011, 12:587-593.
-
(2011)
EMBO Rep.
, vol.12
, pp. 587-593
-
-
Iglesias, N.1
-
19
-
-
0027988467
-
Transcription of a yeast telomere alleviates telomere position effect without affecting chromosome stability
-
Sandell L.L., et al. Transcription of a yeast telomere alleviates telomere position effect without affecting chromosome stability. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:12061-12065.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 12061-12065
-
-
Sandell, L.L.1
-
20
-
-
0036682516
-
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants
-
Maringele L., Lydall D. EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev. 2002, 16:1919-1933.
-
(2002)
Genes Dev.
, vol.16
, pp. 1919-1933
-
-
Maringele, L.1
Lydall, D.2
-
21
-
-
77957243987
-
The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
-
Redon S., et al. The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res. 2010, 38:5797-5806.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 5797-5806
-
-
Redon, S.1
-
22
-
-
78650153788
-
TERRA transcripts are bound by a complex array of RNA-binding proteins
-
de Silanes I.L., et al. TERRA transcripts are bound by a complex array of RNA-binding proteins. Nat. Commun. 2010, 1:1-9.
-
(2010)
Nat. Commun.
, vol.1
, pp. 1-9
-
-
de Silanes, I.L.1
-
23
-
-
84886051117
-
A three-state model for the regulation of telomerase by TERRA and hnRNPA1
-
Redon S., et al. A three-state model for the regulation of telomerase by TERRA and hnRNPA1. Nucleic Acids Res. 2013, 41:9117-9128.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 9117-9128
-
-
Redon, S.1
-
24
-
-
84884564107
-
Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres
-
Cusanelli E., et al. Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres. Mol. Cell 2013, 51:780-791.
-
(2013)
Mol. Cell
, vol.51
, pp. 780-791
-
-
Cusanelli, E.1
-
25
-
-
35748941663
-
Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast
-
Arneric M., Lingner J. Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast. EMBO Rep. 2007, 8:1080-1085.
-
(2007)
EMBO Rep.
, vol.8
, pp. 1080-1085
-
-
Arneric, M.1
Lingner, J.2
-
26
-
-
34547731434
-
Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae
-
Sabourin M., et al. Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol. Cell 2007, 27:550-561.
-
(2007)
Mol. Cell
, vol.27
, pp. 550-561
-
-
Sabourin, M.1
-
27
-
-
34548269900
-
Tel1p preferentially associates with short telomeres to stimulate their elongation
-
Hector R.E., et al. Tel1p preferentially associates with short telomeres to stimulate their elongation. Mol. Cell 2007, 27:851-858.
-
(2007)
Mol. Cell
, vol.27
, pp. 851-858
-
-
Hector, R.E.1
-
28
-
-
77955757670
-
Evolution of CST function in telomere maintenance
-
Price C.M., et al. Evolution of CST function in telomere maintenance. Cell Cycle 2010, 9:3157-3165.
-
(2010)
Cell Cycle
, vol.9
, pp. 3157-3165
-
-
Price, C.M.1
-
29
-
-
84865263603
-
The human CST complex is a terminator of telomerase activity
-
Chen L.Y., et al. The human CST complex is a terminator of telomerase activity. Nature 2012, 488:540-544.
-
(2012)
Nature
, vol.488
, pp. 540-544
-
-
Chen, L.Y.1
-
30
-
-
79953033701
-
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA
-
Flynn R.L., et al. TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA. Nature 2011, 471:532-536.
-
(2011)
Nature
, vol.471
, pp. 532-536
-
-
Flynn, R.L.1
-
31
-
-
76249110370
-
How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA
-
Nandakumar J., et al. How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:651-656.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 651-656
-
-
Nandakumar, J.1
-
32
-
-
84860456242
-
Removal of shelterin reveals the telomere end-protection problem
-
Sfeir A., de Lange T. Removal of shelterin reveals the telomere end-protection problem. Science 2012, 336:593-597.
-
(2012)
Science
, vol.336
, pp. 593-597
-
-
Sfeir, A.1
de Lange, T.2
-
33
-
-
34548317418
-
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
-
Denchi E.L., de Lange T. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 2007, 448:1068-1071.
-
(2007)
Nature
, vol.448
, pp. 1068-1071
-
-
Denchi, E.L.1
de Lange, T.2
-
34
-
-
84896730316
-
TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres
-
Porro A., et al. TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres. Cell Rep. 2014, 6:765-776.
-
(2014)
Cell Rep.
, vol.6
, pp. 765-776
-
-
Porro, A.1
-
35
-
-
68949198783
-
TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres
-
Deng Z., et al. TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol. Cell 2009, 35:403-413.
-
(2009)
Mol. Cell
, vol.35
, pp. 403-413
-
-
Deng, Z.1
-
36
-
-
84858634824
-
Transcription regulates telomere dynamics in human cancer cells
-
Arora R., et al. Transcription regulates telomere dynamics in human cancer cells. RNA 2012, 18:684-693.
-
(2012)
RNA
, vol.18
, pp. 684-693
-
-
Arora, R.1
-
37
-
-
57049132043
-
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
-
Dimitrova N., et al. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 2008, 456:524-528.
-
(2008)
Nature
, vol.456
, pp. 524-528
-
-
Dimitrova, N.1
-
38
-
-
62849108417
-
Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy
-
Wang X., et al. Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy. Epigenetics Chromatin 2008, 1:4.
-
(2008)
Epigenetics Chromatin
, vol.1
, pp. 4
-
-
Wang, X.1
-
39
-
-
32944458421
-
The human RNA surveillance factor UPF1 is required for S phase progression and genome stability
-
Azzalin C.M., Lingner J. The human RNA surveillance factor UPF1 is required for S phase progression and genome stability. Curr. Biol. 2006, 16:433-439.
-
(2006)
Curr. Biol.
, vol.16
, pp. 433-439
-
-
Azzalin, C.M.1
Lingner, J.2
-
40
-
-
0037381155
-
A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed
-
Reichenbach P., et al. A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed. Curr. Biol. 2003, 13:568-574.
-
(2003)
Curr. Biol.
, vol.13
, pp. 568-574
-
-
Reichenbach, P.1
-
41
-
-
2942572923
-
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells
-
Brumbaugh K.M., et al. The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol. Cell 2004, 14:585-598.
-
(2004)
Mol. Cell
, vol.14
, pp. 585-598
-
-
Brumbaugh, K.M.1
-
42
-
-
80053615725
-
Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication
-
Chawla R., et al. Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication. EMBO J. 2011, 30:4047-4058.
-
(2011)
EMBO J.
, vol.30
, pp. 4047-4058
-
-
Chawla, R.1
-
43
-
-
34548353924
-
Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation
-
Tarpey P.S., et al. Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation. Nat. Genet. 2007, 39:1127-1133.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1127-1133
-
-
Tarpey, P.S.1
-
44
-
-
84887053583
-
The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening
-
Pfeiffer V., et al. The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening. EMBO J. 2013, 32:2861-2871.
-
(2013)
EMBO J.
, vol.32
, pp. 2861-2871
-
-
Pfeiffer, V.1
-
45
-
-
84885429957
-
Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence
-
Balk B., et al. Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence. Nat. Struct. Mol. Biol. 2013, 20:1199-1205.
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1199-1205
-
-
Balk, B.1
-
46
-
-
84860338675
-
R loops: from transcription byproducts to threats to genome stability
-
Aguilera A., Garcia-Muse T. R loops: from transcription byproducts to threats to genome stability. Mol. Cell 2012, 46:115-124.
-
(2012)
Mol. Cell
, vol.46
, pp. 115-124
-
-
Aguilera, A.1
Garcia-Muse, T.2
-
47
-
-
77951133257
-
Alternative lengthening of telomeres: models, mechanisms and implications
-
Cesare A.J., Reddel R.R. Alternative lengthening of telomeres: models, mechanisms and implications. Nat. Rev. Genet. 2010, 11:319-330.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 319-330
-
-
Cesare, A.J.1
Reddel, R.R.2
-
48
-
-
0027266758
-
An alternative pathway for yeast telomere maintenance rescues est1- senescence
-
Lundblad V., Blackburn E.H. An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell 1993, 73:347-360.
-
(1993)
Cell
, vol.73
, pp. 347-360
-
-
Lundblad, V.1
Blackburn, E.H.2
-
49
-
-
84859895605
-
Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans
-
Lackner D.H., et al. Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans. EMBO J. 2012, 31:2024-2033.
-
(2012)
EMBO J.
, vol.31
, pp. 2024-2033
-
-
Lackner, D.H.1
-
50
-
-
62549122535
-
Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription
-
Ng L.J., et al. Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription. Nucleic Acids Res. 2009, 37:1152-1159.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 1152-1159
-
-
Ng, L.J.1
-
51
-
-
84899017741
-
Alternative lengthening of telomeres is characterized by reduced compaction of telomeric chromatin
-
Episkopou H., et al. Alternative lengthening of telomeres is characterized by reduced compaction of telomeric chromatin. Nucleic Acids Res. 2014, 42:4391-4405.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 4391-4405
-
-
Episkopou, H.1
-
52
-
-
50849099769
-
Hypomethylation of subtelomeric regions in ICF syndrome is associated with abnormally short telomeres and enhanced transcription from telomeric regions
-
Yehezkel S., et al. Hypomethylation of subtelomeric regions in ICF syndrome is associated with abnormally short telomeres and enhanced transcription from telomeric regions. Hum. Mol. Genet. 2008, 17:2776-2789.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 2776-2789
-
-
Yehezkel, S.1
-
53
-
-
77954165748
-
SiRNA-mediated methylation of Arabidopsis telomeres
-
Vrbsky J., et al. siRNA-mediated methylation of Arabidopsis telomeres. PLoS Genet. 2010, 6:e1000986.
-
(2010)
PLoS Genet.
, vol.6
, pp. e1000986
-
-
Vrbsky, J.1
-
54
-
-
84889056254
-
A quantitative telomeric chromatin isolation protocol identifies different telomeric states
-
Grolimund L., et al. A quantitative telomeric chromatin isolation protocol identifies different telomeric states. Nat. Commun. 2013, 4:2848.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2848
-
-
Grolimund, L.1
|