메뉴 건너뛰기




Volumn 15, Issue 4, 2016, Pages 1453-1466

Simultaneous metabolite, protein, lipid extraction (SIMPLEX): A combinatorial multimolecular omics approach for systems biology

Author keywords

[No Author keywords available]

Indexed keywords

1 ACYLGLYCEROPHOSPHATE ACYLTRANSFERASE; ALPHA ACTININ 1; CERAMIDE; DIACYLGLYCEROL; FATTY ACID BINDING PROTEIN; GLUCOSE TRANSPORTER 4; GLUTATHIONE; GLYCEROLIPID; GLYCEROPHOSPHOLIPID; HISTONE H4; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDATE PHOSPHATASE; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL; PROLINE; PROTEIN; RECEPTOR INTERACTING PROTEIN 140; RIBOFLAVIN; SERINE; SPHINGOMYELIN; SUCCINIC ACID; TRYPTOPHAN;

EID: 84995387150     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M115.053702     Document Type: Article
Times cited : (108)

References (66)
  • 1
    • 84860482342 scopus 로고    scopus 로고
    • A ceramide-centric view of insulin resistance
    • Chavez, J. A., and Summers, S. A. (2012) A ceramide-centric view of insulin resistance. Cell Metabolism 15, 585-594
    • (2012) Cell Metabolism , vol.15 , pp. 585-594
    • Chavez, J.A.1    Summers, S.A.2
  • 3
    • 84871720518 scopus 로고    scopus 로고
    • Ceramide-orchestrated signalling in cancer cells
    • Morad, S. A., and Cabot, M. C. (2013) Ceramide-orchestrated signalling in cancer cells. Nature Rev. Cancer 13, 51- 65
    • (2013) Nature Rev. Cancer , vol.13 , pp. 51-65
    • Morad, S.A.1    Cabot, M.C.2
  • 6
  • 7
  • 9
    • 38149129507 scopus 로고    scopus 로고
    • Ceramide induces p38 MAPK-dependent apoptosis and Bax translocation via inhibition of Akt in HL-60 cells
    • Kim, H. J., Oh, J. E., Kim, S. W., Chun, Y. J., and Kim, M. Y. (2008)Ceramide induces p38 MAPK-dependent apoptosis and Bax translocation via inhibition of Akt in HL-60 cells. Cancer Lett. 260, 88-95
    • (2008) Cancer Lett. , vol.260 , pp. 88-95
    • Kim, H.J.1    Oh, J.E.2    Kim, S.W.3    Chun, Y.J.4    Kim, M.Y.5
  • 10
    • 61549109860 scopus 로고    scopus 로고
    • Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
    • Mukhopadhyay, A., Saddoughi, S. A., Song, P., Sultan, I., Ponnusamy, S., Senkal, C. E., Snook, C. F., Arnold, H. K., Sears, R. C., Hannun, Y. A., and Ogretmen, B. (2009) Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling. FASEB J. 23, 751-763
    • (2009) FASEB J , vol.23 , pp. 751-763
    • Mukhopadhyay, A.1    Saddoughi, S.A.2    Song, P.3    Sultan, I.4    Ponnusamy, S.5    Senkal, C.E.6    Snook, C.F.7    Arnold, H.K.8    Sears, R.C.9    Hannun, Y.A.10    Ogretmen, B.11
  • 11
    • 84902667430 scopus 로고    scopus 로고
    • Controlling low rates of cell differentiation through noise and ultrahigh feedback
    • Ahrends, R., Ota, A., Kovary, K. M., Kudo, T., Park, B. O., and Teruel, M. N. (2014) Controlling low rates of cell differentiation through noise and ultrahigh feedback. Science 344, 1384-1389
    • (2014) Science , vol.344 , pp. 1384-1389
    • Ahrends, R.1    Ota, A.2    Kovary, K.M.3    Kudo, T.4    Park, B.O.5    Teruel, M.N.6
  • 12
    • 84868155607 scopus 로고    scopus 로고
    • Consecutive positive feedback loops create a bistable switch that controls preadipocyte-toadipocyte conversion
    • Park, B. O., Ahrends, R., and Teruel, M. N. (2012) Consecutive positive feedback loops create a bistable switch that controls preadipocyte-toadipocyte conversion. Cell Rep. 2, 976-990
    • (2012) Cell Rep , vol.2 , pp. 976-990
    • Park, B.O.1    Ahrends, R.2    Teruel, M.N.3
  • 13
    • 0033083803 scopus 로고    scopus 로고
    • Crossregulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
    • Wu, Z., Rosen, E. D., Brun, R., Hauser, S., Adelmant, G., Troy, A. E., McKeon, C., Darlington, G. J., and Spiegelman, B. M. (1999) Crossregulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol. Cell 3, 151-158
    • (1999) Mol. Cell , vol.3 , pp. 151-158
    • Wu, Z.1    Rosen, E.D.2    Brun, R.3    Hauser, S.4    Adelmant, G.5    Troy, A.E.6    McKeon, C.7    Darlington, G.J.8    Spiegelman, B.M.9
  • 14
    • 34547928769 scopus 로고    scopus 로고
    • TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells
    • Buczynski, M. W., Stephens, D. L., Bowers-Gentry, R. C., Grkovich, A., Deems, R. A., and Dennis, E. A. (2007) TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells. J. Biol. Chem. 282, 22834-22847
    • (2007) J. Biol. Chem. , vol.282 , pp. 22834-22847
    • Buczynski, M.W.1    Stephens, D.L.2    Bowers-Gentry, R.C.3    Grkovich, A.4    Deems, R.A.5    Dennis, E.A.6
  • 16
    • 84915820372 scopus 로고    scopus 로고
    • Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs
    • Meierhofer, D., Weidner, C., and Sauer, S. (2014) Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs. J. Proteome Res. 13, 5592-5602
    • (2014) J. Proteome Res. , vol.13 , pp. 5592-5602
    • Meierhofer, D.1    Weidner, C.2    Sauer, S.3
  • 17
    • 18844460394 scopus 로고    scopus 로고
    • Sample preparation and digestion for proteomic analyses using spin filters
    • Manza, L. L., Stamer, S. L., Ham, A. J., Codreanu, S. G., and Liebler, D. C. (2005) Sample preparation and digestion for proteomic analyses using spin filters. Proteomics 5, 1742-1745
    • (2005) Proteomics , vol.5 , pp. 1742-1745
    • Manza, L.L.1    Stamer, S.L.2    Ham, A.J.3    Codreanu, S.G.4    Liebler, D.C.5
  • 19
    • 84922391197 scopus 로고    scopus 로고
    • Fast, efficient, and qualitycontrolled phosphopeptide enrichment from minute sample amounts using titanium dioxide
    • Dickhut, C., Radau, S., and Zahedi, R. P. (2014) Fast, efficient, and qualitycontrolled phosphopeptide enrichment from minute sample amounts using titanium dioxide. Meth. Mol. Biol. 1156, 417- 430
    • (2014) Meth. Mol. Biol. , vol.1156 , pp. 417-430
    • Dickhut, C.1    Radau, S.2    Zahedi, R.P.3
  • 20
    • 84855877960 scopus 로고    scopus 로고
    • Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MSbased proteomics
    • 22166745
    • Burkhart, J. M., Schumbrutzki, C., Wortelkamp, S., Sickmann, A., and Zahedi, R. P. (2012) Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MSbased proteomics. J. Proteomics 75, 1454-1462 22166745
    • (2012) J. Proteomics , vol.75 , pp. 1454-1462
    • Burkhart, J.M.1    Schumbrutzki, C.2    Wortelkamp, S.3    Sickmann, A.4    Zahedi, R.P.5
  • 21
    • 84866093349 scopus 로고    scopus 로고
    • TiSH-A robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC
    • Engholm-Keller, K., Birck, P., Størling, J., Pociot, F., Mandrup-Poulsen, T., and Larsen, M. R. (2012) TiSH-a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2 , SIMAC, and HILIC. J. Proteomics 75, 5749-5761
    • (2012) J. Proteomics , vol.75 , pp. 5749-5761
    • Engholm-Keller, K.1    Birck, P.2    Størling, J.3    Pociot, F.4    Mandrup-Poulsen, T.5    Larsen, M.R.6
  • 22
    • 0027305020 scopus 로고
    • Synthesis of a fluorescent derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, and its application for the analysis of hydrolysate amino acids via highperformance liquid chromatography
    • Cohen, S. A., and Michaud, D. P. (1993) Synthesis of a fluorescent derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, and its application for the analysis of hydrolysate amino acids via highperformance liquid chromatography. Anal. Biochem. 211, 279-287
    • (1993) Anal. Biochem , vol.211 , pp. 279-287
    • Cohen, S.A.1    Michaud, D.P.2
  • 23
    • 0031570789 scopus 로고    scopus 로고
    • Separation of 18 6-aminoquinolyl-carbamyl-amino acids by ionpair chromatography
    • Shindo, N., Nojima, S., Fujimura, T., Taka, H., Mineki, R., and Murayama, K. (1997) Separation of 18 6-aminoquinolyl-carbamyl-amino acids by ionpair chromatography. Anal. Biochem. 249, 79-82
    • (1997) Anal. Biochem , vol.249 , pp. 79-82
    • Shindo, N.1    Nojima, S.2    Fujimura, T.3    Taka, H.4    Mineki, R.5    Murayama, K.6
  • 24
    • 84856328361 scopus 로고    scopus 로고
    • Shotgun lipidomics on a LTQ Orbitrap mass spectrometer by successive switching between acquisition polarity modes
    • Schuhmann, K., Almeida, R., Baumert, M., Herzog, R., Bornstein, S. R., and Shevchenko, A. (2012) Shotgun lipidomics on a LTQ Orbitrap mass spectrometer by successive switching between acquisition polarity modes. J. Mass Spectrom. 47, 96-104
    • (2012) J. Mass Spectrom. , vol.47 , pp. 96-104
    • Schuhmann, K.1    Almeida, R.2    Baumert, M.3    Herzog, R.4    Bornstein, S.R.5    Shevchenko, A.6
  • 26
    • 78651516935 scopus 로고    scopus 로고
    • A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language
    • Herzog, R., Schwudke, D., Schuhmann, K., Sampaio, J. L., Bornstein, S. R., Schroeder, M., and Shevchenko, A. (2011) A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language. Genome Biol. 12, R8
    • (2011) Genome Biol. , vol.12 , pp. R8
    • Herzog, R.1    Schwudke, D.2    Schuhmann, K.3    Sampaio, J.L.4    Bornstein, S.R.5    Schroeder, M.6    Shevchenko, A.7
  • 28
    • 68049100110 scopus 로고    scopus 로고
    • Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
    • Bennett, B. D., Kimball, E. H., Gao, M., Osterhout, R., Van Dien, S. J., and Rabinowitz, J. D. (2009) Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nat. Chem. Biol. 5, 593-599
    • (2009) Nat. Chem. Biol. , vol.5 , pp. 593-599
    • Bennett, B.D.1    Kimball, E.H.2    Gao, M.3    Osterhout, R.4    Van Dien, S.J.5    Rabinowitz, J.D.6
  • 29
    • 84915751034 scopus 로고    scopus 로고
    • Novel quantitative metabolomic approach for the study of stress responses of plant root metabolism
    • Li, K., Wang, X., Pidatala, V. R., Chang, C. P., and Cao, X. (2014) Novel quantitative metabolomic approach for the study of stress responses of plant root metabolism. J. Proteome Res. 13, 5879-5887
    • (2014) J. Proteome Res. , vol.13 , pp. 5879-5887
    • Li, K.1    Wang, X.2    Pidatala, V.R.3    Chang, C.P.4    Cao, X.5
  • 30
    • 79951750784 scopus 로고    scopus 로고
    • SearchGUI: An open-source graphical user interface for simultaneous OMSSA and X!Tandem searches
    • Vaudel, M., Barsnes, H., Berven, F. S., Sickmann, A., and Martens, L. (2011)SearchGUI: An open-source graphical user interface for simultaneous OMSSA and X!Tandem searches. Proteomics 11, 996-999
    • (2011) Proteomics , vol.11 , pp. 996-999
    • Vaudel, M.1    Barsnes, H.2    Berven, F.S.3    Sickmann, A.4    Martens, L.5
  • 34
  • 36
    • 33244483352 scopus 로고    scopus 로고
    • OP9 mouse stromal cells rapidly differentiate into adipocytes: Characterization of a useful new model of adipogenesis
    • Wolins, N. E., Quaynor, B. K., Skinner, J. R., Tzekov, A., Park, C., Choi, K., and Bickel, P. E. (2006) OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis. J. Lipid Res. 47, 450-460
    • (2006) J. Lipid Res. , vol.47 , pp. 450-460
    • Wolins, N.E.1    Quaynor, B.K.2    Skinner, J.R.3    Tzekov, A.4    Park, C.5    Choi, K.6    Bickel, P.E.7
  • 37
    • 84868570014 scopus 로고    scopus 로고
    • Comprehensive lipidome profiling of isogenic primary and metastatic colon adenocarcinoma cell lines
    • Fhaner, C. J., Liu, S., Ji, H., Simpson, R. J., and Reid, G. E. (2012)Comprehensive lipidome profiling of isogenic primary and metastatic colon adenocarcinoma cell lines. Anal. Chem. 84, 8917-8926
    • (2012) Anal. Chem , vol.84 , pp. 8917-8926
    • Fhaner, C.J.1    Liu, S.2    Ji, H.3    Simpson, R.J.4    Reid, G.E.5
  • 38
    • 84860352139 scopus 로고    scopus 로고
    • A positive/ negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue
    • Yuan, M., Breitkopf, S. B., Yang, X., and Asara, J. M. (2012) A positive/ negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue. Nature Protocols 7, 872- 881
    • (2012) Nature Protocols , vol.7 , pp. 872-881
    • Yuan, M.1    Breitkopf, S.B.2    Yang, X.3    Asara, J.M.4
  • 39
    • 67349266694 scopus 로고    scopus 로고
    • Universal sample preparation method for proteome analysis
    • Wiśniewski, J. R., Zougman, A., Nagaraj, N., and Mann, M. (2009) Universal sample preparation method for proteome analysis. Nat. Methods 6, 359-362
    • (2009) Nat. Methods , vol.6 , pp. 359-362
    • Wiśniewski, J.R.1    Zougman, A.2    Nagaraj, N.3    Mann, M.4
  • 40
    • 50049096775 scopus 로고    scopus 로고
    • XCMS2: Processing tandem mass spectrometry data for metabolite identification and structural characterization
    • Benton, H. P., Wong, D. M., Trauger, S. A., and Siuzdak, G. (2008) XCMS2: Processing tandem mass spectrometry data for metabolite identification and structural characterization. Anal. Chem. 80, 6382-6389
    • (2008) Anal. Chem. , vol.80 , pp. 6382-6389
    • Benton, H.P.1    Wong, D.M.2    Trauger, S.A.3    Siuzdak, G.4
  • 41
    • 84908545013 scopus 로고    scopus 로고
    • Targeted metabolomics in cultured cells and tissues by mass spectrometry: Method development and validation
    • Abdel Rahman, A. M., Pawling, J., Ryczko, M., Caudy, A. A., and Dennis, J. W. (2014) Targeted metabolomics in cultured cells and tissues by mass spectrometry: method development and validation. Anal. Chim. Acta 845, 53-61
    • (2014) Anal. Chim. Acta , vol.845 , pp. 53-61
    • Abdel Rahman, A.M.1    Pawling, J.2    Ryczko, M.3    Caudy, A.A.4    Dennis, J.W.5
  • 42
    • 84902440103 scopus 로고    scopus 로고
    • Clinical and non-targeted metabolomic profiling of homozygous carriers of transcription factor 7-like 2 variant rs7903146
    • Wagner, R., Li, J., Kenar, E., Kohlbacher, O., Machicao, F., Häring, H. U., Fritsche, A., Xu, G., and Lehmann, R. (2014) Clinical and non-targeted metabolomic profiling of homozygous carriers of transcription factor 7-like 2 variant rs7903146. Scientific Rep. 4, 5296
    • (2014) Scientific Rep. , vol.4 , pp. 5296
    • Wagner, R.1    Li, J.2    Kenar, E.3    Kohlbacher, O.4    Machicao, F.5    Häring, H.U.6    Fritsche, A.7    Xu, G.8    Lehmann, R.9
  • 45
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification. Can
    • Bligh, E. G., and Dyer, W. J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917
    • (1959) J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 46
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch, J., Lees, M., and Sloane Stanley, G. H. (1957) A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497-509
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 50
    • 84922041416 scopus 로고    scopus 로고
    • A review of odd-chain fatty acid metabolism and the role of pentadecanoic acid (c15:0) and heptadecanoic acid (c17:0) in health and disease
    • Jenkins, B., West, J. A., and Koulman, A. (2015) A review of odd-chain fatty acid metabolism and the role of pentadecanoic acid (c15:0) and heptadecanoic acid (c17:0) in health and disease. Molecules 20, 2425-2444
    • (2015) Molecules , vol.20 , pp. 2425-2444
    • Jenkins, B.1    West, J.A.2    Koulman, A.3
  • 52
    • 84930216251 scopus 로고    scopus 로고
    • Single-cell mass spectrometry reveals small molecules that affect cell fates in the 16-cell embryo
    • Onjiko, R. M., Moody, S. A., and Nemes, P. (2015) Single-cell mass spectrometry reveals small molecules that affect cell fates in the 16-cell embryo. Proc. Natl. Acad. Sci. U.S.A. 112, 6545-6550
    • (2015) Proc. Natl. Acad. Sci. U. S. A , vol.112 , pp. 6545-6550
    • Onjiko, R.M.1    Moody, S.A.2    Nemes, P.3
  • 54
    • 34547118326 scopus 로고    scopus 로고
    • In-depth analysis of the adipocyte proteome by mass spectrometry and bioinformatics
    • Adachi, J., Kumar, C., Zhang, Y., and Mann, M. (2007) In-depth analysis of the adipocyte proteome by mass spectrometry and bioinformatics. Mol. Cell. Proteomics 6, 1257-1273
    • (2007) Mol. Cell. Proteomics , vol.6 , pp. 1257-1273
    • Adachi, J.1    Kumar, C.2    Zhang, Y.3    Mann, M.4
  • 55
    • 1942456595 scopus 로고    scopus 로고
    • Sequential gene promoter interactions by C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis
    • Tang, Q. Q., Zhang, J. W., and Daniel Lane, M. (2004) Sequential gene promoter interactions by C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis. Biochem. Biophys. Res. Commun. 318, 213-218
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 213-218
    • Tang, Q.Q.1    Zhang, J.W.2    Daniel Lane, M.3
  • 57
    • 0036236733 scopus 로고    scopus 로고
    • Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: Ahomeoviscous-longevity adaptation?
    • Pamplona, R., Barja, G., and Portero-Otín, M. (2002) Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: Ahomeoviscous-longevity adaptation? Ann. N.Y. Acad. Sci. 959, 475-490
    • (2002) Ann. N.Y. Acad. Sci. , vol.959 , pp. 475-490
    • Pamplona, R.1    Barja, G.2    Portero-Otín, M.3
  • 58
    • 67449091887 scopus 로고    scopus 로고
    • Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion
    • Lee, H., Lee, Y. J., Choi, H., Ko, E. H., and Kim, J. W. (2009) Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion. J. Biol. Chem. 284, 10601-10609
    • (2009) J. Biol. Chem. , vol.284 , pp. 10601-10609
    • Lee, H.1    Lee, Y.J.2    Choi, H.3    Ko, E.H.4    Kim, J.W.5
  • 59
    • 17644413626 scopus 로고    scopus 로고
    • Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2
    • Simon, M. F., Daviaud, D., Pradère, J. P., Grès, S., Guigné, C., Wabitsch, M., Chun, J., Valet, P., and Saulnier-Blache, J. S. (2005) Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2. J. Biol. Chem. 280, 14656-14662
    • (2005) J. Biol. Chem. , vol.280 , pp. 14656-14662
    • Simon, M.F.1    Daviaud, D.2    Pradère, J.P.3    Grès, S.4    Guigné, C.5    Wabitsch, M.6    Chun, J.7    Valet, P.8    Saulnier-Blache, J.S.9
  • 60
    • 66849089697 scopus 로고    scopus 로고
    • Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis
    • Takeuchi, K., and Reue, K. (2009) Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis. Am. J. Physiol. Endocrinol. Metabolism 296, E1195-1209
    • (2009) Am. J. Physiol. Endocrinol. Metabolism , vol.296 , pp. E1195-E1209
    • Takeuchi, K.1    Reue, K.2
  • 61
    • 33744954152 scopus 로고    scopus 로고
    • A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation
    • Gale, S. E., Frolov, A., Han, X., Bickel, P. E., Cao, L., Bowcock, A., Schaffer, J. E., and Ory, D. S. (2006) A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation. J. Biol. Chem. 281, 11082-11089
    • (2006) J. Biol. Chem. , vol.281 , pp. 11082-11089
    • Gale, S.E.1    Frolov, A.2    Han, X.3    Bickel, P.E.4    Cao, L.5    Bowcock, A.6    Schaffer, J.E.7    Ory, D.S.8
  • 63
    • 33749125215 scopus 로고    scopus 로고
    • Biophysical properties of lipids and dynamic membranes
    • Janmey, P. A., and Kinnunen, P. K. (2006) Biophysical properties of lipids and dynamic membranes. Trends Cell Biol. 16, 538-546
    • (2006) Trends Cell Biol. , vol.16 , pp. 538-546
    • Janmey, P.A.1    Kinnunen, P.K.2
  • 65
    • 2142652105 scopus 로고    scopus 로고
    • Sequential ordered fatty acid alpha oxidation and Delta9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes
    • Su, X., Han, X., Yang, J., Mancuso, D. J., Chen, J., Bickel, P. E., and Gross, R. W. (2004) Sequential ordered fatty acid alpha oxidation and Delta9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes. Biochemistry 43, 5033-5044
    • (2004) Biochemistry , vol.43 , pp. 5033-5044
    • Su, X.1    Han, X.2    Yang, J.3    Mancuso, D.J.4    Chen, J.5    Bickel, P.E.6    Gross, R.W.7
  • 66
    • 84995384901 scopus 로고    scopus 로고
    • Protein lipid modifications-More than just a greasy ballast
    • Hentschel, A., Zahedi, R. P., and Ahrends, R. (2015) Protein lipid modifications-More than just a greasy ballast. Proteomics.
    • (2015) Proteomics
    • Hentschel, A.1    Zahedi, R.P.2    Ahrends, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.