ChREBP regulates fructose-induced glucose production independently of insulin signaling

Journal of Clinical Investigation

Volumn 126, Issue 11, 2016, Pages 4372-4386

  Kim, Mi Sung ^a   Krawczyk, Sarah A ^a   Doridot, Ludivine ^a   Fowler, Alan J ^a   Wang, Jennifer X ^b   Trauger, Sunia A ^b   Noh, Hye Lim ^c   Kang, Hee Joon ^c   Meissen, John K ^d   Blatnik, Matthew ^d   Kim, Jason K ^c   Lai, Michelle ^a   Herman, Mark A ^a,e  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CARBOHYDRATE RESPONSIVE ELEMENT BINDING PROTEIN; FRUCTOSE; GLUCOSE 6 PHOSPHATASE; HEXOSE PHOSPHATE; INSULIN; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; FOXO1 PROTEIN, MOUSE; GLUCOSE; MLXIPL PROTEIN, HUMAN; MLXIPL PROTEIN, MOUSE; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FATTY LIVER; FEMALE; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; GLYCOGENOLYSIS; HOMEOSTASIS; HUMAN; HYPERINSULINEMIA; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; LIPOGENESIS; LIVER BIOPSY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; GLYCOLYSIS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; FATTY LIVER; FEMALE; FORKHEAD BOX PROTEIN O1; FRUCTOSE; GLUCOSE; GLUCOSE INTOLERANCE; GLUCOSE-6-PHOSPHATASE; GLYCOLYSIS; HUMANS; INSULIN; INSULIN RESISTANCE; LIPOGENESIS; MALE; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84994666911     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI81993     Document Type: Article

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