Novel mechanism of positive versus negative regulation by thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver

Journal of Biological Chemistry

Volumn 289, Issue 3, 2014, Pages 1313-1328

  Ramadoss, Preeti ^a   Abraham, Brian J ^b   Tsai, Linus ^a   Zhou, Yiming ^a   Costa E Sousa, Ricardo H ^a   Ye, Felix ^a   Bilban, Martin ^c   Zhao, Keji ^b   Hollenberg, Anthony N ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

GENOME-WIDE PROFILING; KNOWN TARGET GENES; METABOLIC PROCESS; MOUSE LIVER; NUCLEAR RECEPTORS; STRONG CORRELATION; THYROID HORMONE RECEPTOR; TRANSCRIPTIONAL REGULATION;

ENDOCRINOLOGY; GENE EXPRESSION;

HORMONES;

DEATH RECEPTOR 4; LIOTHYRONINE; THYROID HORMONE RECEPTOR BETA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE TARGETING; GENETIC ASSOCIATION; GENOME ANALYSIS; IN VIVO STUDY; LIVER; MALE; MOUSE; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MOTIF; TRANSCRIPTION REGULATION; TRB1 GENE; ANIMAL; CELL LINE; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; CELL LINE; GENE EXPRESSION REGULATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LIVER; MICE; MICE, TRANSGENIC; RESPONSE ELEMENTS; THYROID HORMONE RECEPTORS BETA; TRANSCRIPTION, GENETIC; TRIIODOTHYRONINE;

EID: 84892660787     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.521450     Document Type: Article

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