Fructose 2, 6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

Biochemical Journal

Volumn 443, Issue 1, 2012, Pages 111-123

  Arden, Catherine ^a   Tudhope, Susan J ^a   Petrie, John L ^a   Al Oanzi, Ziad H ^a,b   Cullen, Kirsty S ^a   Lange, Alex J ^c   Towle, Howard C ^c   Agius, Loranne ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b JOUF UNIVERSITY   (Saudi Arabia)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Carbohydrate response element binding protein (ChREBP); Fructose 2,6 bisphosphate; Glucose 6 phosphate; Glucose 6 phosphatase; Hepatocyte

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE FRUCTOSE 2,6 BIPHOSPHATASE; ACTIVATING TRANSCRIPTION FACTOR 4; CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN; FRUCTOSE 2,6 BISPHOSPHATASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; MESSENGER RNA; SERINE; UNCLASSIFIED DRUG; XYLITOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLUCOSE METABOLISM; LIVER CELL; MALE; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELLS, CULTURED; DEOXYGLUCOSE; DIHYDROXYACETONE; FRUCTOSEDIPHOSPHATES; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE-6-PHOSPHATASE; GLYCOLYSIS; HEPATOCYTES; HEXOSAMINES; MALE; PHOSPHOFRUCTOKINASE-2; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; RATS, WISTAR; XYLITOL;

EID: 84858327557     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111280     Document Type: Article

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