Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

eLife

Volumn 5, Issue September2016, 2016, Pages

  Horlbeck, Max A ^a,b,c   Gilbert, Luke A ^a,b,c   Villalta, Jacqueline E ^a,b,c   Adamson, Britt ^a,b,c   Pak, Ryan A ^a,d   Chen, Yuwen ^a,b,c   Fields, Alexander P ^a,b,c   Park, Chong Yon ^a,d   Corn, Jacob E ^d   Kampmann, Martin ^a,b,c   Weissman, Jonathan S ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; OLIGONUCLEOTIDE; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; ENDONUCLEASE; GUIDE RNA; NUCLEOSOME;

ALGORITHM; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; FEMALE; GAIN OF FUNCTION MUTATION; GENE ACTIVATION; GENE OVEREXPRESSION; GENE REPRESSION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HUMAN CELL; LIBRARY; LINEAR REGRESSION ANALYSIS; MACHINE LEARNING; MOLECULAR GENETICS; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM; SEQUENCE ANALYSIS; ANIMAL; CHROMOSOMAL MAPPING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENE TARGETING; METABOLISM; MOUSE; NUCLEOSOME; PROCEDURES;

ANIMALS; BACTERIAL PROTEINS; CHROMOSOME MAPPING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; ENDONUCLEASES; GENE TARGETING; HUMANS; MICE; NUCLEOSOMES; RNA, GUIDE;

EID: 84994418123     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.19760     Document Type: Article

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