On the Potential Origins of the High Stability of Reconstructed Ancestral Proteins

Molecular Biology and Evolution

Volumn 33, Issue 10, 2016, Pages 2633-2641

  Trudeau, Devin L ^a   Kaltenbach, Miriam ^a   Tawfik, Dan S ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

ancestral inference; consensus effect; protein evolution; protein stability; serum paraoxonase (PON); thermostability

Indexed keywords

ARYLDIALKYLPHOSPHATASE; ARYLESTERASE; BACTERIAL PROTEIN; CARBOXYLESTERASE;

AMINO ACID SEQUENCE; ARTICLE; ENVIRONMENTAL TEMPERATURE; ESCHERICHIA COLI; IONIZING RADIATION; MOLECULAR EVOLUTION; NONHUMAN; OXIDATIVE STRESS; PHYLOGENETIC TREE; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN STABILITY; THERMOSTABILITY; ANIMAL; BLOOD; ENZYME STABILITY; GENETICS; HEAT; HUMAN; METABOLISM; PHYLOGENY; PROCEDURES; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; ARYLDIALKYLPHOSPHATASE; BACTERIAL PROTEINS; CARBOXYLIC ESTER HYDROLASES; ENZYME STABILITY; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; HOT TEMPERATURE; HUMANS; PHYLOGENY; PROTEIN STABILITY; SEQUENCE ALIGNMENT;

EID: 84994130151     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msw138     Document Type: Article

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